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Hi. I'm doing TAD calling using Chromosome.find_tad on two samples that have 5kb resolution. At first I did the calling with add_experiment(..., resolution=5000), but that resulted in very small TADs. After that, I tried with resolution=40000 and the TADs look good (see figure below)
However, there are still two chromosomes that have very small TADs, chr13 for example:
I tried to re-run those chromosomes with 20k and 80k resolution to no avail, it still results in small TADs.
I'm running pytadbit v1.0.1 (pytadbit.version says v1.1 though) and this is my code:
Hi. I'm doing TAD calling using
Chromosome.find_tad
on two samples that have 5kb resolution. At first I did the calling withadd_experiment(..., resolution=5000)
, but that resulted in very small TADs. After that, I tried with resolution=40000 and the TADs look good (see figure below)However, there are still two chromosomes that have very small TADs, chr13 for example:
I tried to re-run those chromosomes with 20k and 80k resolution to no avail, it still results in small TADs.
I'm running pytadbit v1.0.1 (pytadbit.version says v1.1 though) and this is my code:
Any insight would be appreciated, thank you.
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