Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Include all transcripts in report and genes overview. #363

Open
northwestwitch opened this issue Sep 30, 2024 · 3 comments
Open

Include all transcripts in report and genes overview. #363

northwestwitch opened this issue Sep 30, 2024 · 3 comments
Labels
Enhancement New feature or request question Further information is requested

Comments

@northwestwitch
Copy link
Member

northwestwitch commented Sep 30, 2024

When I originally started developing chanjo2 I kind of copied the behavior of chanjo -> Include in stats onlt transcripts associated with mRNA. For instance the POT gene has several transcripts:

image

But only the first 2 will be used in the report/genes overview:

image

Now I wonder if it's case to change and include all transcripts. This will slow down reports, especially those with many genes, but they'll be more informative for sure

NOTE that all transcripts are included when creating the gene overview page

@northwestwitch northwestwitch added the question Further information is requested label Sep 30, 2024
@Jakob37
Copy link
Collaborator

Jakob37 commented Oct 1, 2024

Just speaking for Lund. I don't think the geneticists here in Lund generally would be interested in all transcripts. The reverse, I think they would (generally) prefer just the MANE transcript subset, to focus computational time and attention on what matters for them.

But might be a good idea for others!

What do you think about having this somehow configurable? Such that a user can select which set of transcripts is of interest.

@northwestwitch
Copy link
Member Author

What do you think about having this somehow configurable? Such that a user can select which set of transcripts is of interest.

That's a good idea. I'll ask our clinicians this week and we'll see. But perhaps we keep this for next release. I'd really like to have the upcoming one ready and out after merging #361, so we'll something usable in production.

@Jakob37
Copy link
Collaborator

Jakob37 commented Oct 1, 2024

What do you think about having this somehow configurable? Such that a user can select which set of transcripts is of interest.

That's a good idea. I'll ask our clinicians this week and we'll see. But perhaps we keep this for next release. I'd really like to have the upcoming one ready and out after merging #361, so we'll something usable in production.

Sounds very good 👌

@northwestwitch northwestwitch added the Enhancement New feature or request label Oct 1, 2024
Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
Enhancement New feature or request question Further information is requested
Projects
None yet
Development

No branches or pull requests

2 participants