All nf-core pipelines have been successfully configured for the use on the HPC (griffin) at Cancer Research UK Manchester Institute.
To use, run the pipeline with -profile crukmi
. This will download and launch the crukmi.config
which has been pre-configured with a setup suitable for the Griffin HPC. Using this profile, Apptainer/Singularity images will be downloaded to run on the cluster and stored in a centralised location.
Before running the pipeline you will need to load Nextflow using the environment module system, for example via:
## Load Nextflow environment modules
module purge
module load apps/nextflow
The pipeline should always be executed inside a workspace on the /scratch/
system. All of the intermediate files required to run the pipeline will be stored in the work/
directory. It is recommended to delete this directory after the pipeline has finished successfully because it can get quite large.