These are the scripts specific to the Frontiers in Cellular Neuroscience publication:

Title: Inhibiting presynaptic calcium channel motility in the auditory cortex suppresses synchronized input processing

Authors: Katrina E. Deane, Ruslan Klymentiev, Jennifer Heck, Frank W. Ohl, Martin Heine, Max F. K. Happel

https://www.frontiersin.org/articles/10.3389/fncel.2024.1369047

Please cite us if you use these scripts

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Necessary to run:

Raw data for this project can be found at: https://figshare.com/s/5000eeb8946f1b8fd33e Animal raw data (e.g "KIC01_0001.mat") should be placed in ../Deane_etal_2024/Raw;

Order to run and summary of steps:

If animal raw data files are placed correctly in \Deane_etal_2022\Raw, running the Pipeline01_MatLab.m script will produce

• single CSD figures
• group average CSD figures
• Data structure per animal with all measurement data (lfp, csd, avrec, relres, absres)
• single AVREC and layer traces
• single trial peak detection csv per animal (to be compiled into AVRECPeakCLST.csv and AVRECPeakAMST.csv)
• group average AVREC and layer traces

If AVRECPeakCLST.csv and AVRECPeakAMST.csv is in \Deane_etal_2022\Data\PeakDataCSV, running Pipeline02_LMM.R will produce

• LMM html files in \Deane_etal_2022\Data\LMMstats
• NOTE: these master files need to be manually compiled by copying data from per-subject single trial peak data output of Deane_etal_2022\Scripts\MatLab\ChangeInAvrecSTperAnimal, run from the Pipeline01_MatLab script (can be run independantly if data already exists from previous runs)

Then running Pipeline03_Julia.jl will produce

• cohen's d and student's t test graphs and data output

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Please raise an issue in this repository if something is not running. Thank you!