From 0109374694cdfc1cecac4c6eb56bfd70d2925903 Mon Sep 17 00:00:00 2001 From: Sandy Rogers Date: Mon, 29 Jan 2024 10:17:16 +0000 Subject: [PATCH] Feature/ebi search dump migration (#332) This PR: * adds management commands to dump XML dumps of Studies ("projects") and Analyses ("runs") for EBI Search indexing. * updates the schema of the dumps. In particular, we no longer separately index samples; instead the relevant sample metadata is dumped onto the analyses listing. A sample may appear twice, if there are multiple analyses of it, but this is acceptable. * updates a few mongo queries, by introducing lazy references. By default these do not fetch the other side of references fields (e.g. the description of an interpro identifier found in an analysis). Instead, they just return the PK. * Since the PKs for these fields are usually all we need to xref annotations to the foreign db (e.g., interpro), and are adequate for a user to search for (e.g., by searching an IPRxxxx accession), this is a fine optimisation to make the search dump run in reasonable time. * makes (at least some) last_updated fields be auto-nows. This is so that if the object changes, it'll be included in the next incremental EBI Search indexing. Co-authored-by: Martin Beracochea --- .dockerignore | 30 + .github/workflows/test.yml | 4 + .gitignore | 18 +- .../commands/ebi_search_analysis_dump.py | 216 + .../commands/ebi_search_study_dump.py | 108 + ...5_last_updates_on_ebi_searchable_models.py | 33 + emgapi/migrations/0016_auto_20240117_1757.py | 22 + emgapi/models.py | 78 +- emgapi/serializers.py | 4 +- .../templates/ebi_search/analyses-deletes.xml | 8 + emgapi/templates/ebi_search/analyses.xml | 11 + emgapi/templates/ebi_search/analysis.xml | 89 + .../ebi_search/example_MGYA00238154.xml | 17205 +++++++++++ .../ebi_search/example_MGYA00374984.xml | 24630 ++++++++++++++++ .../templates/ebi_search/projects-deletes.xml | 8 + emgapi/templates/ebi_search/projects.xml | 40 + emgapianns/models.py | 113 +- emgapianns/utils.py | 25 + emgcli/__init__.py | 2 +- emgcli/settings.py | 15 +- pyproject.toml | 2 +- tests/api/test_study.py | 16 +- tests/test_utils/emg_fixtures.py | 2 +- 23 files changed, 42623 insertions(+), 56 deletions(-) create mode 100644 .dockerignore create mode 100644 emgapi/management/commands/ebi_search_analysis_dump.py create mode 100644 emgapi/management/commands/ebi_search_study_dump.py create mode 100644 emgapi/migrations/0015_last_updates_on_ebi_searchable_models.py create mode 100644 emgapi/migrations/0016_auto_20240117_1757.py create mode 100644 emgapi/templates/ebi_search/analyses-deletes.xml create mode 100644 emgapi/templates/ebi_search/analyses.xml create mode 100644 emgapi/templates/ebi_search/analysis.xml create mode 100644 emgapi/templates/ebi_search/example_MGYA00238154.xml create mode 100644 emgapi/templates/ebi_search/example_MGYA00374984.xml create mode 100644 emgapi/templates/ebi_search/projects-deletes.xml create mode 100644 emgapi/templates/ebi_search/projects.xml create mode 100644 emgapianns/utils.py diff --git a/.dockerignore b/.dockerignore new file mode 100644 index 000000000..bbd25333e --- /dev/null +++ b/.dockerignore @@ -0,0 +1,30 @@ +.DS_Store +db.sqlite3 +__pycache__ +*.pyc +var +dist +.eggs +emgcli.egg-info/ +.pytest_cache/ + +staticfiles/ +media/ +venv/ +database/ +results/ +fixtures/*.sig + +.vscode/ + +# IntelliJ project structure files +*.iml +.idea/ + +.coverage +/build/ + +loglockdir +logs + +secret.key \ No newline at end of file diff --git a/.github/workflows/test.yml b/.github/workflows/test.yml index 99fcb913d..49e075edb 100644 --- a/.github/workflows/test.yml +++ b/.github/workflows/test.yml @@ -38,6 +38,10 @@ jobs: pip install install .[tests] pip freeze + - name: Check for unmigrated code changes + run: | + python emgcli/manage.py makemigrations --noinput --check --dry-run + - name: ๐Ÿงช - Testing run: | cat $EMG_CONFIG diff --git a/.gitignore b/.gitignore index 10dc9625f..14cd294c5 100644 --- a/.gitignore +++ b/.gitignore @@ -8,7 +8,6 @@ dist emgcli.egg-info/ .pytest_cache/ - staticfiles/ media/ venv/ @@ -20,7 +19,6 @@ fixtures/*.sig # IntelliJ project structure files *.iml -*.xml .idea/ .coverage @@ -29,4 +27,18 @@ fixtures/*.sig loglockdir logs -secret.key \ No newline at end of file +secret.key + +dumps + +/config/*.yml +/config/*.yaml +!/config/*local* + +/config/*.yml +/config/*.yaml +!/config/*local* + +/config/*.yml +/config/*.yaml +!/config/*local* \ No newline at end of file diff --git a/emgapi/management/commands/ebi_search_analysis_dump.py b/emgapi/management/commands/ebi_search_analysis_dump.py new file mode 100644 index 000000000..39d9fd12d --- /dev/null +++ b/emgapi/management/commands/ebi_search_analysis_dump.py @@ -0,0 +1,216 @@ +#!/usr/bin/env python +# -*- coding: utf-8 -*- + +# Copyright 2017-2023 EMBL - European Bioinformatics Institute +# +# Licensed under the Apache License, Version 2.0 (the "License"); +# you may not use this file except in compliance with the License. +# You may obtain a copy of the License at +# http://www.apache.org/licenses/LICENSE-2.0 +# +# Unless required by applicable law or agreed to in writing, software +# distributed under the License is distributed on an "AS IS" BASIS, +# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. +# See the License for the specific language governing permissions and +# limitations under the License. + +import logging +import pathlib +from datetime import timedelta +from typing import Optional + +from django.core.management import BaseCommand +from django.core.paginator import Paginator +from django.db.models import QuerySet +from django.template.loader import render_to_string +from django.utils import timezone + +from emgapi.models import AnalysisJob +from emgapianns.models import ( + AnalysisJobTaxonomy, + AnalysisJobGoTerm, + AnalysisJobInterproIdentifier, +) + +logger = logging.getLogger(__name__) + + +class Command(BaseCommand): + help = "Generate the XML dump of analyses for EBI Search." + + def add_arguments(self, parser): + super(Command, self).add_arguments(parser) + parser.add_argument( + "--full", + action="store_true", + help="Create a full snapshot rather than incremental.", + ) + parser.add_argument("-o", "--output", help="Output dir for xml files", required=True) + parser.add_argument("-c", "--chunk", help="Number of analyses per chunk", default=100, nargs='?', type=int) + parser.add_argument("-m", "--max_pages", help="Max number of pages to dump", default=-1, type=int) + + def get_analysis_context(self, analysis: AnalysisJob): + try: + analysis_taxonomy: Optional[AnalysisJobTaxonomy] = AnalysisJobTaxonomy.objects.get( + pk=str(analysis.job_id) + ) + except AnalysisJobTaxonomy.DoesNotExist: + logger.debug(f"Could not find analysis job taxonomy for {analysis.job_id}") + analysis_taxonomy = None + + try: + go_annotation: Optional[AnalysisJobGoTerm] = AnalysisJobGoTerm.objects.get( + pk=str(analysis.job_id) + ) + except AnalysisJobGoTerm.DoesNotExist: + logger.debug(f"Could not find go terms for {analysis.job_id}") + go_annotation = None + + try: + ips_annotation: Optional[AnalysisJobInterproIdentifier] = AnalysisJobInterproIdentifier.objects.get( + pk=str(analysis.job_id) + ) + except AnalysisJobInterproIdentifier.DoesNotExist: + logger.debug(f"Could not find IPS terms for {analysis.job_id}") + ips_annotation = None + + biome_list = analysis.study.biome.lineage.split(":")[1:] or ['root'] + # to ensure there are no empty hierarchical fields + + taxonomy_lists = [] + if analysis_taxonomy: + taxonomy_attributes = [ + analysis_taxonomy.taxonomy, + analysis_taxonomy.taxonomy_ssu, + analysis_taxonomy.taxonomy_lsu, + analysis_taxonomy.taxonomy_itsonedb, + analysis_taxonomy.taxonomy_itsunite, + ] + for taxonomy_attribute in taxonomy_attributes: + if taxonomy_attribute: + for tax in taxonomy_attribute: + tax_lineage_list = list(filter(None, tax.organism.pk.split('|')[0].split(":"))) + if len(tax_lineage_list) > 1: + taxonomy_lists.append( + tax_lineage_list + ) + + sample_numeric_fields_to_index = { + "temperature": "temperature", + "pH": "pH", + "altitude": "altitude", + "depth": "depth", + "elevation": "elevation", + "geographic location (elevation)": "elevation", + "geographic location (depth)": "depth", + "salinity": "salinity", + "longitude start": "longitudeStart", + "latitude start": "latitudeStart", + "longitude end": "longitudeEnd", + "latitude end": "latitudeEnd", + } + + sample_text_annotations_to_index = { + "sequencing method": "sequencing_method", + "geographic location (region and locality)": "location_name", + "geographic location (country and/or sea,region)": "location_name", + "disease status": "disease_status", + "phenotype": "phenotype", + } + + sample_annotations_to_index = sample_numeric_fields_to_index.copy() + sample_annotations_to_index.update(sample_text_annotations_to_index) + + sample_metadata = {} + for sample_metadata_entry in analysis.sample.metadata.all(): + if (vn := sample_metadata_entry.var.var_name) in sample_annotations_to_index: + indexable_name = sample_annotations_to_index[vn] + indexable_value = sample_metadata_entry.var_val_ucv + + if indexable_name in sample_numeric_fields_to_index.values(): + try: + indexable_value = float(indexable_value.strip()) + except ValueError: + logger.debug( + f"Could not float-parse supposedly numeric field {indexable_name} : {indexable_value}") + continue + sample_metadata[ + indexable_name + ] = indexable_value + + if 'location_name' not in sample_metadata and analysis.sample.geo_loc_name: + sample_metadata['location_name'] = analysis.sample.geo_loc_name + return { + "analysis": analysis, + "analysis_biome": biome_list, + "analysis_taxonomies": taxonomy_lists, + "analysis_go_entries": [go.go_term.pk for go in go_annotation.go_terms] if go_annotation else [], + "analysis_ips_entries": [ipr.interpro_identifier.pk for ipr in ips_annotation.interpro_identifiers] if ips_annotation else [], + # .pk ensures the IPR and GO documents are not queried on mongo, which would have a big performance hit + "sample_metadata": sample_metadata, + } + + @staticmethod + def write_without_blank_lines(fp, string): + fp.write( + "\n".join( + filter( + str.strip, + string.splitlines() + ) + ) + ) + + def handle(self, *args, **options): + """Dump EBI Search XML file of analyses""" + is_full_snapshot: str = options["full"] + output_dir: str = options["output"] + chunk_size: int = options["chunk"] + + pathlib.Path(output_dir).mkdir(parents=True, exist_ok=True) + + analyses: QuerySet = AnalysisJob.objects_dump.available(None) + + if not is_full_snapshot: + analyses = AnalysisJob.objects_for_indexing.to_add() + + removals = AnalysisJob.objects_for_indexing.to_delete() + + # produce incremental deletion file + deletions_file = pathlib.Path(output_dir) / pathlib.Path('analyses-deletes.xml') + with open(deletions_file, 'w') as d: + self.write_without_blank_lines(d, + render_to_string( + "ebi_search/analyses-deletes.xml", + { + "removals": removals + } + ) + ) + + paginated_analyses = Paginator(analyses, chunk_size) + + for page in paginated_analyses: + if (mp := options["max_pages"]) >= 0: + if page.number > mp: + logger.warning("Skipping remaining pages") + break + logger.info(f"Dumping {page.number = }/{paginated_analyses.num_pages}") + additions_file = pathlib.Path(output_dir) / pathlib.Path(f'analyses_{page.number:04}.xml') + with open(additions_file, 'w') as a: + self.write_without_blank_lines(a, + render_to_string( + "ebi_search/analyses.xml", + { + "additions": (self.get_analysis_context(analysis) for analysis in page), + "count": len(page) + } + ) + ) + nowish = timezone.now() + timedelta(minutes=1) + # Small buffer into the future so that the indexing time remains ahead of auto-now updated times. + + for analysis in page: + analysis.last_indexed = nowish + + AnalysisJob.objects.bulk_update(page, fields=["last_indexed"]) diff --git a/emgapi/management/commands/ebi_search_study_dump.py b/emgapi/management/commands/ebi_search_study_dump.py new file mode 100644 index 000000000..888529262 --- /dev/null +++ b/emgapi/management/commands/ebi_search_study_dump.py @@ -0,0 +1,108 @@ +#!/usr/bin/env python +# -*- coding: utf-8 -*- + +# Copyright 2017-2023 EMBL - European Bioinformatics Institute +# +# Licensed under the Apache License, Version 2.0 (the "License"); +# you may not use this file except in compliance with the License. +# You may obtain a copy of the License at +# http://www.apache.org/licenses/LICENSE-2.0 +# +# Unless required by applicable law or agreed to in writing, software +# distributed under the License is distributed on an "AS IS" BASIS, +# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. +# See the License for the specific language governing permissions and +# limitations under the License. + +import logging +import pathlib +from datetime import timedelta + +from django.core.management import BaseCommand +from django.db.models import QuerySet +from django.template.loader import render_to_string +from django.utils import timezone + +from emgapi.models import Study + +logger = logging.getLogger(__name__) + + +class Command(BaseCommand): + help = "Generate the XML dump of studies for EBI Search." + + def add_arguments(self, parser): + super(Command, self).add_arguments(parser) + parser.add_argument( + "--full", + action="store_true", + help="Create a full snapshot rather than incremental.", + ) + parser.add_argument("-o", "--output", help="Output dir for xml files", required=True) + + + @staticmethod + def write_without_blank_lines(fp, string): + fp.write( + "\n".join( + filter( + str.strip, + string.splitlines() + ) + ) + ) + + @staticmethod + def get_study_context(study: Study): + biome_list = study.biome.lineage.split(":")[1:] or ['root'] + + return { + "study": study, + "biome_list": biome_list + } + + def handle(self, *args, **options): + """Dump EBI Search XML file of studies/projects""" + is_full_snapshot: str = options["full"] + output_dir: str = options["output"] + + pathlib.Path(output_dir).mkdir(parents=True, exist_ok=True) + + studies: QuerySet = Study.objects.available(None) + + if not is_full_snapshot: + studies = Study.objects_for_indexing.to_add() + + removals = Study.objects_for_indexing.to_delete() + + # produce incremental deletion file + deletions_file = pathlib.Path(output_dir) / pathlib.Path('projects-deletes.xml') + with open(deletions_file, 'w') as d: + self.write_without_blank_lines(d, + render_to_string( + "ebi_search/projects-deletes.xml", + { + "removals": removals + } + ) + ) + + additions_file = pathlib.Path(output_dir) / pathlib.Path('projects.xml') + with open(additions_file, 'w') as a: + self.write_without_blank_lines(a, + render_to_string( + "ebi_search/projects.xml", + { + "additions": (self.get_study_context(study) for study in studies), + "count": studies.count() + } + ) + ) + + nowish = timezone.now() + timedelta(minutes=1) + # Small buffer into the future so that the indexing time remains ahead of auto-now updated times. + + for study in studies: + study.last_indexed = nowish + + Study.objects.bulk_update(studies, fields=["last_indexed"]) diff --git a/emgapi/migrations/0015_last_updates_on_ebi_searchable_models.py b/emgapi/migrations/0015_last_updates_on_ebi_searchable_models.py new file mode 100644 index 000000000..ce0b239ac --- /dev/null +++ b/emgapi/migrations/0015_last_updates_on_ebi_searchable_models.py @@ -0,0 +1,33 @@ +# Generated by Django 3.2.18 on 2023-11-10 13:29 + +from django.db import migrations, models + + +class Migration(migrations.Migration): + + dependencies = [ + ('emgapi', '0014_suppression_reason_ancestor_suppressed'), + ] + + operations = [ + migrations.AddField( + model_name='analysisjob', + name='last_indexed', + field=models.DateTimeField(blank=True, db_column='LAST_INDEXED', help_text='Date at which this model was last included in an EBI Search initial/incremental index.', null=True), + ), + migrations.AddField( + model_name='analysisjob', + name='last_update', + field=models.DateTimeField(auto_now=True, db_column='LAST_UPDATE'), + ), + migrations.AddField( + model_name='study', + name='last_indexed', + field=models.DateTimeField(blank=True, db_column='LAST_INDEXED', help_text='Date at which this model was last included in an EBI Search initial/incremental index.', null=True), + ), + migrations.AlterField( + model_name='study', + name='last_update', + field=models.DateTimeField(auto_now=True, db_column='LAST_UPDATE'), + ), + ] diff --git a/emgapi/migrations/0016_auto_20240117_1757.py b/emgapi/migrations/0016_auto_20240117_1757.py new file mode 100644 index 000000000..17f1520b1 --- /dev/null +++ b/emgapi/migrations/0016_auto_20240117_1757.py @@ -0,0 +1,22 @@ +# Generated by Django 3.2.23 on 2024-01-17 17:57 + +from django.db import migrations + + +class Migration(migrations.Migration): + + dependencies = [ + ('emgapi', '0015_last_updates_on_ebi_searchable_models'), + ] + + operations = [ + migrations.AlterModelOptions( + name='blacklistedstudy', + options={'managed': False, 'verbose_name': 'blacklisted study', 'verbose_name_plural': 'blacklisted studies'}, + ), + migrations.RenameField( + model_name='analysisjob', + old_name='analysis_summary_json', + new_name='analysis_summary', + ), + ] diff --git a/emgapi/models.py b/emgapi/models.py index e51921928..9d0830c04 100644 --- a/emgapi/models.py +++ b/emgapi/models.py @@ -18,9 +18,10 @@ from django.apps import apps from django.conf import settings +from django.core.exceptions import FieldDoesNotExist from django.db import models from django.db.models import (CharField, Count, OuterRef, Prefetch, Q, - Subquery, Value, QuerySet) + Subquery, Value, QuerySet, F) from django.db.models.functions import Cast, Concat from django.utils import timezone @@ -278,6 +279,67 @@ class Meta: abstract = True +class EbiSearchIndexQueryset(models.QuerySet): + """ + to_delete: Objects that have been suppressed since they were last indexed, + or that have been indexed but updated since. + + to_add: Objects that have never been indexed, + or that have been indexed but updated since. + """ + def to_delete(self): + updated_after_indexing = Q(last_update__gte=F("last_indexed"), last_indexed__isnull=False) + + try: + self.model._meta.get_field("suppressed_at") + except FieldDoesNotExist: + return self.filter( + updated_after_indexing + ) + else: + return self.filter( + Q(suppressed_at__gte=F("last_indexed")) | updated_after_indexing + ) + + def to_add(self): + updated_after_indexing = Q(last_update__gte=F("last_indexed"), last_indexed__isnull=False) + never_indexed = Q(last_indexed__isnull=True) + + try: + self.model._meta.get_field("is_suppressed") + except FieldDoesNotExist: + not_suppressed = Q() + else: + not_suppressed = Q(is_suppressed=False) + + try: + self.model._meta.get_field("is_private") + except FieldDoesNotExist: + not_private = Q() + else: + not_private = Q(is_private=False) + + return self.filter(never_indexed | updated_after_indexing, not_suppressed, not_private) + + +class EbiSearchIndexedModel(models.Model): + last_update = models.DateTimeField( + db_column='LAST_UPDATE', + auto_now=True + ) + last_indexed = models.DateTimeField( + db_column='LAST_INDEXED', + null=True, + blank=True, + help_text="Date at which this model was last included in an EBI Search initial/incremental index." + ) + + objects_for_indexing = EbiSearchIndexQueryset.as_manager() + + class Meta: + abstract = True + + class BaseQuerySet(models.QuerySet): """Auth mechanism to filter private / suppressed models """ @@ -964,7 +1026,7 @@ def mydata(self, request): return self.get_queryset().mydata(request) -class Study(ENASyncableModel): +class Study(ENASyncableModel, EbiSearchIndexedModel): suppressible_descendants = ['samples', 'runs', 'assemblies', 'analyses'] def __init__(self, *args, **kwargs): @@ -999,7 +1061,7 @@ def _custom_pk(self): author_name = models.CharField( db_column='AUTHOR_NAME', max_length=100, blank=True, null=True) last_update = models.DateTimeField( - db_column='LAST_UPDATE') + db_column='LAST_UPDATE', auto_now=True) submission_account_id = models.CharField( db_column='SUBMISSION_ACCOUNT_ID', max_length=15, blank=True, null=True) @@ -1626,7 +1688,14 @@ def available(self, request): return self.get_queryset().available(request) -class AnalysisJob(SuppressibleModel, PrivacyControlledModel): +class AnalysisJobDumpManager(AnalysisJobManager): + def get_queryset(self): + return AnalysisJobQuerySet(self.model, using=self._db) \ + .select_related( + 'analysis_status','experiment_type', 'assembly', 'pipeline', 'run', 'sample', 'study') + + +class AnalysisJob(SuppressibleModel, PrivacyControlledModel, EbiSearchIndexedModel): def __init__(self, *args, **kwargs): super(AnalysisJob, self).__init__(*args, **kwargs) setattr(self, 'accession', @@ -1699,6 +1768,7 @@ def downloads(self): objects = AnalysisJobManager() objects_admin = models.Manager() + objects_dump = AnalysisJobDumpManager() class Meta: db_table = 'ANALYSIS_JOB' diff --git a/emgapi/serializers.py b/emgapi/serializers.py index f55f71401..0079a0c66 100644 --- a/emgapi/serializers.py +++ b/emgapi/serializers.py @@ -1020,7 +1020,8 @@ class Meta: 'secondary_accession', 'is_suppressed', 'suppressed_at', - 'suppression_reason' + 'suppression_reason', + 'last_indexed' ) @@ -1409,6 +1410,7 @@ class Meta: 'is_suppressed', 'suppression_reason', 'suppressed_at', + 'last_indexed', ) diff --git a/emgapi/templates/ebi_search/analyses-deletes.xml b/emgapi/templates/ebi_search/analyses-deletes.xml new file mode 100644 index 000000000..a8ae25841 --- /dev/null +++ b/emgapi/templates/ebi_search/analyses-deletes.xml @@ -0,0 +1,8 @@ + + EMG_run + + {% for entry in removals %} + + {% endfor %} + + diff --git a/emgapi/templates/ebi_search/analyses.xml b/emgapi/templates/ebi_search/analyses.xml new file mode 100644 index 000000000..c90e395a1 --- /dev/null +++ b/emgapi/templates/ebi_search/analyses.xml @@ -0,0 +1,11 @@ + + EMG_run + EMG Analysis runs โ€“ samples analysed by MGnify pipelines + {% now "Y-m-d" %} + {{ count }} + + {% for a in additions %} + {% include "ebi_search/analysis.xml" with analysis=a.analysis analysis_biome=a.analysis_biome analysis_taxonomies=a.analysis_taxonomies analysis_go_entries=a.analysis_go_entries analysis_ips_entries=a.analysis_ips_entries sample_metadata=a.sample_metadata only %} + {% endfor %} + + diff --git a/emgapi/templates/ebi_search/analysis.xml b/emgapi/templates/ebi_search/analysis.xml new file mode 100644 index 000000000..3ca50375e --- /dev/null +++ b/emgapi/templates/ebi_search/analysis.xml @@ -0,0 +1,89 @@ + + + {{ analysis.accession }} + + + + + + + {{ analysis.experiment_type.experiment_type }} + {{ analysis.pipeline.release_version }} + {{ analysis.sample.sample_name | escape }} + {{ analysis.sample.sample_desc | escape }} + {{ analysis.study.study_name | escape }} + {{ analysis.study.biome.biome_name | escape }} + + {% if analysis.sample.species %} + {{ analysis.sample.species | escape }} + {% endif %} + + {% if analysis.sample.environment_feature %} + {{ analysis.sample.environment_feature | escape }} + {% endif %} + + {% if analysis.sample.environment_material %} + {{ analysis.sample.environment_material | escape }} + {% endif %} + + {{ analysis.sample.sample_alias | escape }} + {{ analysis.study.study_name | escape }} + + + {% for biome_element in analysis_biome %} + {% if forloop.first %} + {{ biome_element | escape }} + {% else %} + {{ biome_element | escape }} + {% endif %} + {% endfor %} + + + {% for metadata_key, metadata_value in sample_metadata.items %} + {{ metadata_value | escape }} + {% endfor %} + + {% for taxonomy_lineage_elements in analysis_taxonomies %} + + {% for taxonomy_element in taxonomy_lineage_elements %} + {% if forloop.first %} + {{ taxonomy_element | escape }} + {% else %} + {{ taxonomy_element | escape }} + {% endif %} + {% endfor %} + + {% endfor %} + + + + + + {# biosample #} + {% if analysis.sample.primary_accession %} + + {% endif %} + + {# INSDC sample like DRSxx, ERSxx, SRSxx #} + {% if analysis.sample.accession and analysis.sample.accession|slice:"1:3" == "RS"%} + + {% endif %} + + {# Assembly analysis #} + {% if analysis.assembly %} + + {% endif %} + + {# WGS/Amplicon analysis #} + {% if analysis.run %} + + {% endif %} + + {% for go in analysis_go_entries %} + + {% endfor %} + {% for ips in analysis_ips_entries %} + + {% endfor %} + + \ No newline at end of file diff --git a/emgapi/templates/ebi_search/example_MGYA00238154.xml b/emgapi/templates/ebi_search/example_MGYA00238154.xml new file mode 100644 index 000000000..e4fe8b45e --- /dev/null +++ b/emgapi/templates/ebi_search/example_MGYA00238154.xml @@ -0,0 +1,17205 @@ + + MGYA00238154 + + + + + + assembly + 4.1 + Gp0206847 + EMG produced TPA metagenomics assembly of the Chrysochromulina tobin associated microbial communities from unialgal haptophyte culture, Washington, USA - P5_4mM MetaG metagenome (mixed culture metagenome) data set. + Brackish + + Environmental + Aquatic + Lentic + Brackish + + oxidation-reduction process + metabolic process + transmembrane transport + protein phosphorylation + regulation of transcription, DNA-templated + proteolysis + transport + translation + carbohydrate metabolic process + ion transport + microtubule-based movement + biosynthetic process + protein folding + DNA repair + signal transduction + cell redox homeostasis + DNA recombination + protein ubiquitination + lipid metabolic process + tRNA aminoacylation for protein translation + DNA integration + phosphorelay signal transduction system + RNA processing + protein glycosylation + intracellular protein transport + DNA replication + potassium ion transport + transcription, DNA-templated + nucleobase-containing compound metabolic process + pseudouridine synthesis + protein peptidyl-prolyl isomerization + cation transport + tRNA processing + RNA modification + cellular protein modification process + ubiquitin-dependent protein catabolic process + vesicle-mediated transport + glycolytic process + nitrogen compound metabolic process + dephosphorylation + methylation + phosphorylation + rRNA processing + protein ADP-ribosylation + protein deubiquitination + cellular amino acid metabolic process + fatty acid biosynthetic process + metal ion transport + intracellular signal transduction + ATP synthesis coupled proton transport + DNA topological change + carbohydrate transport + photosynthesis + tricarboxylic acid cycle + tRNA modification + protein transport + magnesium ion transport + DNA-templated transcription, initiation + fatty acid metabolic process + tRNA aminoacylation + potassium ion transmembrane transport + cyclic nucleotide biosynthetic process + peptidyl-amino acid modification + histidine biosynthetic process + nucleoside metabolic process + response to stress + lipid biosynthetic process + protein secretion + drug transmembrane transport + response to oxidative stress + base-excision repair + mismatch repair + translational initiation + cellular aromatic compound metabolic process + sodium ion transport + isoprenoid biosynthetic process + pathogenesis + nucleotide-excision repair + transposition, DNA-mediated + lysine biosynthetic process via diaminopimelate + glucose metabolic process + DNA methylation + porphyrin-containing compound biosynthetic process + ammonium transport + proteolysis involved in cellular protein catabolic process + DNA replication initiation + cytochrome complex assembly + amino acid transmembrane transport + Mo-molybdopterin cofactor biosynthetic process + sulfate transport + ATP hydrolysis coupled proton transport + purine nucleotide biosynthetic process + phospholipid biosynthetic process + tetrapyrrole biosynthetic process + cobalamin biosynthetic process + translational elongation + microtubule-based process + aromatic amino acid family biosynthetic process + riboflavin biosynthetic process + protein metabolic process + protein catabolic process + ribosome biogenesis + 'de novo' pyrimidine nucleobase biosynthetic process + translational termination + SRP-dependent cotranslational protein targeting to membrane + proton transport + protein import + aromatic compound catabolic process + carboxylic acid metabolic process + phosphatidylinositol phosphorylation + telomere maintenance + galactose metabolic process + ubiquinone biosynthetic process + superoxide metabolic process + iron-sulfur cluster assembly + electron transport chain + bacterial-type flagellum-dependent cell motility + gluconeogenesis + 'de novo' IMP biosynthetic process + cysteine biosynthetic process from serine + ATP synthesis coupled electron transport + trehalose biosynthetic process + DNA metabolic process + arginine biosynthetic process + glutathione catabolic process + terpenoid biosynthetic process + phosphatidylinositol metabolic process + intermembrane lipid transfer + nucleosome assembly + mRNA processing + glutathione biosynthetic process + cell adhesion + aerobic respiration + aromatic amino acid family metabolic process + nucleotide catabolic process + ER to Golgi vesicle-mediated transport + vesicle docking involved in exocytosis + negative regulation of transcription, DNA-templated + mRNA splicing, via spliceosome + pyrimidine nucleotide biosynthetic process + tryptophan metabolic process + regulation of pH + vacuolar transport + methionine biosynthetic process + leucine biosynthetic process + lipid A biosynthetic process + folic acid-containing compound biosynthetic process + molybdate ion transport + peptide transport + heme transport + coenzyme A biosynthetic process + guanosine tetraphosphate metabolic process + nitrate assimilation + tRNA threonylcarbamoyladenosine modification + glycerol-3-phosphate metabolic process + nucleoside diphosphate phosphorylation + GTP biosynthetic process + UTP biosynthetic process + CTP biosynthetic process + DNA modification + glycyl-tRNA aminoacylation + glutamate biosynthetic process + protein targeting + cell cycle + queuosine biosynthetic process + cellular amino acid biosynthetic process + branched-chain amino acid biosynthetic process + purine nucleobase biosynthetic process + thiamine biosynthetic process + peptidoglycan biosynthetic process + regulation of ARF protein signal transduction + ATP metabolic process + protein targeting to Golgi + fructose metabolic process + valyl-tRNA aminoacylation + proline biosynthetic process + L-serine biosynthetic process + calcium ion transport + phosphate ion transport + G-protein coupled receptor signaling pathway + NAD biosynthetic process + polysaccharide transport + virion assembly + regulation of Rho protein signal transduction + cell division + ammonium transmembrane transport + polysaccharide biosynthetic process + glycerol metabolic process + (1->3)-beta-D-glucan biosynthetic process + glyoxylate cycle + transcription initiation from RNA polymerase II promoter + arginyl-tRNA aminoacylation + isoleucyl-tRNA aminoacylation + methionine metabolic process + heme biosynthetic process + phosphate-containing compound metabolic process + chloride transport + amino acid transport + microtubule nucleation + regulation of cell shape + peptidoglycan catabolic process + protein secretion by the type II secretion system + pantothenate biosynthetic process + carotenoid biosynthetic process + photosynthesis, light reaction + respiratory electron transport chain + protein refolding + cellular metabolic process + protein insertion into membrane + protein homooligomerization + chromosome organization + cilium assembly + calcium ion transmembrane transport + organic substance metabolic process + carbohydrate derivative metabolic process + microtubule cytoskeleton organization + cell morphogenesis + mannose metabolic process + regulation of transcription from RNA polymerase II promoter + tRNA splicing, via endonucleolytic cleavage and ligation + alanyl-tRNA aminoacylation + phenylalanyl-tRNA aminoacylation + glutamine biosynthetic process + glycine catabolic process + L-phenylalanine catabolic process + polyamine biosynthetic process + steroid biosynthetic process + cytoskeleton organization + cell communication + lipoate biosynthetic process + nucleotide metabolic process + nucleoside triphosphate catabolic process + nucleotide biosynthetic process + chromate transport + lipid catabolic process + protein processing + histone deacetylation + chromosome condensation + tRNA methylation + retrograde transport, endosome to Golgi + pteridine-containing compound metabolic process + poly-hydroxybutyrate biosynthetic process + glycerol-3-phosphate catabolic process + tetrahydrofolate metabolic process + Golgi vesicle transport + DNA ligation involved in DNA repair + rRNA base methylation + protein maturation by iron-sulfur cluster transfer + regulation of cyclin-dependent protein serine/threonine kinase activity + pentose-phosphate shunt + purine nucleotide metabolic process + inosine salvage + dTMP biosynthetic process + DNA-dependent DNA replication + DNA catabolic process + DNA-templated transcription, termination + methionyl-tRNA aminoacylation + signal peptide processing + N-terminal protein amino acid methylation + GPI anchor biosynthetic process + glutamine metabolic process + tyrosine metabolic process + glycerol ether metabolic process + heme a biosynthetic process + anion transport + chemotaxis + immune response + small GTPase mediated signal transduction + isoleucine biosynthetic process + thiamine diphosphate biosynthetic process + phosphoenolpyruvate-dependent sugar phosphotransferase system + response to heat + SOS response + photosynthetic electron transport chain + negative regulation of centrosome duplication + carbon utilization + histone acetylation + tryptophan catabolic process to kynurenine + lipid glycosylation + regulation of actin filament polymerization + regulation of DNA-templated transcription, elongation + Arp2/3 complex-mediated actin nucleation + peptide biosynthetic process + primary metabolic process + formaldehyde catabolic process + chorismate metabolic process + N-4 methylation of cytosine + sulfate assimilation + rRNA modification + selenocysteine incorporation + tRNA wobble uridine modification + fructose 2,6-bisphosphate metabolic process + ethanol oxidation + pyruvate metabolic process + GMP biosynthetic process + double-strand break repair via nonhomologous end joining + glutamyl-tRNA aminoacylation + leucyl-tRNA aminoacylation + lysyl-tRNA aminoacylation + prolyl-tRNA aminoacylation + seryl-tRNA aminoacylation + threonyl-tRNA aminoacylation + tryptophanyl-tRNA aminoacylation + translational frameshifting + protein N-linked glycosylation + protein O-linked glycosylation + arginine metabolic process + sphingolipid metabolic process + ceramide metabolic process + one-carbon metabolic process + heme oxidation + cellular iron ion homeostasis + retrograde vesicle-mediated transport, Golgi to ER + intra-Golgi vesicle-mediated transport + autophagy + multicellular organism development + pyridoxine biosynthetic process + pentose-phosphate shunt, non-oxidative branch + branched-chain amino acid metabolic process + threonine biosynthetic process + L-phenylalanine biosynthetic process + lipopolysaccharide biosynthetic process + glycolipid biosynthetic process + DNA restriction-modification system + photosynthetic electron transport in photosystem II + response to metal ion + chlorophyll biosynthetic process + carbohydrate catabolic process + RNA metabolic process + peroxisome fission + poly(A)+ mRNA export from nucleus + cell wall macromolecule catabolic process + antibiotic biosynthetic process + pyrroloquinoline quinone biosynthetic process + acetyl-CoA biosynthetic process from acetate + aerobic electron transport chain + cellulose catabolic process + molybdopterin cofactor biosynthetic process + phosphate ion transmembrane transport + lipoprotein biosynthetic process + photosystem II stabilization + proteasome-mediated ubiquitin-dependent protein catabolic process + proteasome assembly + cellular respiration + positive regulation of translational elongation + positive regulation of translational termination + response to antibiotic + carbohydrate phosphorylation + phytochelatin biosynthetic process + glucose 6-phosphate metabolic process + nuclear-transcribed mRNA catabolic process, nonsense-mediated decay + allantoin catabolic process + mitotic cell cycle + trehalose metabolic process + fructose 6-phosphate metabolic process + acetyl-CoA biosynthetic process from pyruvate + dTDP biosynthetic process + DNA replication, synthesis of RNA primer + regulation of DNA replication + double-strand break repair + chromatin remodeling + transcription from RNA polymerase II promoter + cysteinyl-tRNA aminoacylation + histidyl-tRNA aminoacylation + tyrosyl-tRNA aminoacylation + C-terminal protein methylation + cysteine metabolic process + S-adenosylmethionine biosynthetic process + protein import into nucleus + protein retention in ER lumen + tetrahydrobiopterin biosynthetic process + ATP biosynthetic process + folic acid-containing compound metabolic process + regulation of nitrogen utilization + oligopeptide transport + cellular amino acid catabolic process + biotin biosynthetic process + peptidoglycan turnover + deoxyribonucleotide catabolic process + DNA mediated transformation + GDP-mannose biosynthetic process + regulation of signal transduction + phospholipid transport + coenzyme A metabolic process + protein arginylation + protein flavinylation + peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase + peptidyl-pyrromethane cofactor linkage + methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione + isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway + pyridine nucleotide biosynthetic process + glycine decarboxylation via glycine cleavage system + L-lysine catabolic process to acetate + glutamate catabolic process to 2-oxoglutarate + 3,4-dihydroxybenzoate catabolic process + GDP-mannose metabolic process + pyrimidine nucleobase biosynthetic process + actin filament polymerization + cellular phosphate ion homeostasis + rRNA methylation + response to ATP + galactose catabolic process via UDP-galactose + copper ion transmembrane transport + arginine biosynthetic process via ornithine + regulation of GTPase activity + proton-transporting ATP synthase complex assembly + 'de novo' UMP biosynthetic process + cellular biosynthetic process + negative regulation of phosphate metabolic process + inositol phosphate dephosphorylation + heme O biosynthetic process + dimethylallyl diphosphate biosynthetic process + barbed-end actin filament capping + cofactor biosynthetic process + protein tetramerization + DNA biosynthetic process + cation transmembrane transport + tRNA-guanine transglycosylation + DNA damage checkpoint + tryptophan biosynthetic process + double-strand break repair via homologous recombination + DNA catabolic process, endonucleolytic + RNA methylation + tRNA wobble adenosine to inosine editing + glucose catabolic process + D-ribose metabolic process + inositol biosynthetic process + amino sugar metabolic process + isocitrate metabolic process + fumarate metabolic process + malate metabolic process + regulation of carbohydrate metabolic process + mitochondrial electron transport, NADH to ubiquinone + mitochondrial electron transport, ubiquinol to cytochrome c + guanine catabolic process + purine ribonucleoside salvage + regulation of DNA repair + chromatin assembly or disassembly + transcription elongation from RNA polymerase II promoter + 7-methylguanosine mRNA capping + transcription from RNA polymerase III promoter + mRNA catabolic process + regulation of translational fidelity + protein complex assembly + N-terminal protein amino acid acetylation + protein methylation + dolichol-linked oligosaccharide biosynthetic process + alanine metabolic process + glycine biosynthetic process + threonine metabolic process + tryptophan catabolic process + tyrosine biosynthetic process + thiamine metabolic process + phosphorus metabolic process + polyphosphate biosynthetic process + nitric oxide biosynthetic process + mitochondrial pyruvate transport + endocytosis + peroxisome organization + mitotic sister chromatid cohesion + mitotic chromosome condensation + protein kinase C-activating G-protein coupled receptor signaling pathway + spermidine biosynthetic process + RNA splicing + coenzyme biosynthetic process + purine ribonucleotide biosynthetic process + ribonucleoside monophosphate biosynthetic process + menaquinone biosynthetic process + protein lipoylation + Entner-Doudoroff pathway through 6-phosphogluconate + nitrogen fixation + toxin biosynthetic process + pyridoxal 5'-phosphate salvage + putrescine biosynthetic process + 7-methylguanosine RNA capping + detection of visible light + flavonoid biosynthetic process + cytidine deamination + response to organic substance + photosystem II assembly + monovalent inorganic cation transport + polyamine transport + formate oxidation + carbon fixation + chlorophyll catabolic process + cellular component organization + carbohydrate biosynthetic process + attachment of GPI anchor to protein + histone modification + protein-heme linkage + peptidyl-glutamic acid carboxylation + peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid + protein prenylation + modulation by virus of host morphology or physiology + response to pheromone + UDP-N-acetylgalactosamine biosynthetic process + inositol catabolic process + siroheme biosynthetic process + allantoin biosynthetic process + removal of superoxide radicals + L-methionine salvage from methylthioadenosine + organic phosphonate catabolic process + actin cytoskeleton organization + regulation of mitotic metaphase/anaphase transition + protein import into mitochondrial matrix + cellulose biosynthetic process + beta-lactam antibiotic catabolic process + mRNA 3'-end processing + arabinan metabolic process + regulation of DNA-templated transcription, termination + regulation of TOR signaling + alanine transport + DNA duplex unwinding + ion transmembrane transport + mitochondrial respiratory chain complex III assembly + iron ion transmembrane transport + intraciliary transport + mature ribosome assembly + cellular modified amino acid biosynthetic process + L-alanine catabolic process + lipoprotein transport + negative regulation of apoptotic process + positive regulation of catalytic activity + Gram-negative-bacterium-type cell outer membrane assembly + urea catabolic process + maintenance of CRISPR repeat elements + RNA polyadenylation + regulation of phosphoprotein phosphatase activity + protein transport by the Tat complex + AMP salvage + bacterial-type flagellum assembly + bacterial-type flagellum organization + glycerolipid biosynthetic process + protein targeting to ER + extracellular polysaccharide biosynthetic process + positive regulation of Notch signaling pathway + positive regulation of transcription, DNA-templated + dUTP metabolic process + 2-keto-3-deoxygluconate transport + tetrahydrofolate biosynthetic process + intracellular transport + vesicle fusion with Golgi apparatus + cell motility + chromosome separation + defense response to virus + copper ion homeostasis + membrane organization + cell wall organization + membrane assembly + alpha-tubulin acetylation + carbohydrate derivative biosynthetic process + p-aminobenzoyl-glutamate transmembrane transport + autophagosome assembly + negative regulation of transcription from RNA polymerase II promoter + spliceosomal complex assembly + peptidoglycan metabolic process + deadenylation-dependent decapping of nuclear-transcribed mRNA + response to reactive oxygen species + generation of catalytic spliceosome for second transesterification step + spliceosomal snRNP assembly + maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) + cleavage involved in rRNA processing + conjugation + regulation of neurotransmitter levels + tRNA 5'-leader removal + polysaccharide metabolic process + monosaccharide metabolic process + fucose metabolic process + UDP-glucose metabolic process + chitin metabolic process + N-acetylglucosamine metabolic process + glucuronate catabolic process + organic acid metabolic process + citrate metabolic process + purine nucleobase metabolic process + IMP biosynthetic process + pyrimidine nucleobase metabolic process + pyrimidine nucleoside metabolic process + uracil salvage + dUTP biosynthetic process + plasmid maintenance + mRNA splice site selection + mRNA cleavage + RNA catabolic process + asparaginyl-tRNA aminoacylation + aspartyl-tRNA aminoacylation + regulation of translational initiation + protein dephosphorylation + arginine catabolic process + asparagine biosynthetic process + glycine metabolic process + threonine catabolic process + spermine biosynthetic process + protein targeting to mitochondrion + phospholipid metabolic process + galactosylceramide catabolic process + NADPH regeneration + NADP biosynthetic process + NADP catabolic process + glutathione metabolic process + sulfur compound metabolic process + copper ion transport + iron ion transport + neurotransmitter transport + lipid transport + exocytosis + nucleocytoplasmic transport + defense response + cellular response to DNA damage stimulus + tubulin complex assembly + post-chaperonin tubulin folding pathway + mitotic spindle assembly checkpoint + regulation of exit from mitosis + reciprocal meiotic recombination + Notch signaling pathway + peptidyl-lysine modification to peptidyl-hypusine + catabolic process + nucleoside catabolic process + purine ribonucleoside monophosphate biosynthetic process + nucleotide-sugar metabolic process + phage shock + amine metabolic process + oligosaccharide biosynthetic process + 2'-deoxyribonucleotide metabolic process + gamma-aminobutyric acid metabolic process + gamma-aminobutyric acid catabolic process + response to toxic substance + photosynthetic electron transport in photosystem I + nodulation + phytochromobilin biosynthetic process + phenylacetate catabolic process + negative regulation of phosphatase activity + ferrous iron transport + organic phosphonate transport + galactose transport + glucose transport + choline transport + siderophore transport + formate metabolic process + rRNA catabolic process + sterol metabolic process + protein-phycocyanobilin linkage + peptidyl-diphthamide biosynthetic process from peptidyl-histidine + viral DNA genome packaging + viral genome replication + glycine betaine biosynthetic process from choline + isopentenyl diphosphate biosynthetic process, mevalonate pathway + cysteine biosynthetic process via cystathionine + dolichol metabolic process + sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) + sulfur oxidation + sulfate reduction + histidine catabolic process to glutamate and formamide + mannitol metabolic process + urea metabolic process + organic phosphonate metabolic process + NAD metabolic process + lipid storage + bacteriocin immunity + protein secretion by the type IV secretion system + prenylcysteine catabolic process + cytoplasmic microtubule organization + anaphase-promoting complex-dependent catabolic process + posttranslational protein targeting to membrane, translocation + glycine betaine transport + cardiolipin biosynthetic process + regulation of barrier septum assembly + inositol trisphosphate metabolic process + positive regulation of transcription elongation from RNA polymerase II promoter + fatty acid beta-oxidation using acyl-CoA dehydrogenase + gamma-tubulin complex localization + mitochondrial respiratory chain complex IV assembly + D-galactonate catabolic process + carbohydrate transmembrane transport + microtubule anchoring + U6 snRNA 3'-end processing + histone lysine methylation + gluconate transmembrane transport + regulation of protein catabolic process + vitamin B6 biosynthetic process + pyridoxal phosphate biosynthetic process + ATP-dependent chromatin remodeling + purine-containing compound salvage + negative regulation of cysteine-type endopeptidase activity involved in apoptotic process + regulation of ATPase activity + benzoate catabolic process + cellular carbohydrate metabolic process + sodium-dependent phosphate transport + [2Fe-2S] cluster assembly + protein neddylation + regulation of angiogenesis + xanthine metabolic process + glycolate biosynthetic process + L-arabinose metabolic process + viral entry into host cell + viral procapsid maturation + replication fork protection + protein stabilization + regulation of sequence-specific DNA binding transcription factor activity + protein oligomerization + kinetochore assembly + regulation of cell cycle + vacuolar proton-transporting V-type ATPase complex assembly + tRNA seleno-modification + DNA-templated transcriptional preinitiation complex assembly + 'de novo' L-methionine biosynthetic process + urea transmembrane transport + conversion of methionyl-tRNA to N-formyl-methionyl-tRNA + mRNA methylation + selenocysteinyl-tRNA(Sec) biosynthetic process + negative regulation of bacterial-type flagellum assembly + mitotic recombination-dependent replication fork processing + membrane + integral component of membrane + cytoplasm + intracellular + ribosome + nucleus + myosin complex + outer membrane-bounded periplasmic space + Golgi membrane + dynein complex + extracellular region + small ribosomal subunit + large ribosomal subunit + chromosome + outer membrane + photosystem II + proteasome core complex + nucleosome + plasma membrane + ATP-binding cassette (ABC) transporter complex + endoplasmic reticulum + membrane coat + proton-transporting ATP synthase complex, catalytic core F(1) + proton-transporting ATP synthase complex, coupling factor F(o) + microtubule + voltage-gated potassium channel complex + photosystem I + clathrin adaptor complex + integral component of plasma membrane + photosystem II oxygen evolving complex + kinesin complex + intracellular ribonucleoprotein complex + proton-transporting two-sector ATPase complex, proton-transporting domain + nuclear pore + glycerol-3-phosphate dehydrogenase complex + extrinsic component of membrane + COPII vesicle coat + small-subunit processome + cell outer membrane + acetyl-CoA carboxylase complex + proton-transporting V-type ATPase, V0 domain + signal recognition particle + 1,3-beta-D-glucan synthase complex + transcription factor complex + microtubule organizing center + beta-galactosidase complex + type II protein secretion system complex + mediator complex + phosphopyruvate hydratase complex + spindle pole + mitochondrial inner membrane + HslUV protease complex + chloroplast + photosystem I reaction center + proteasome core complex, alpha-subunit complex + MCM complex + periplasmic space + spliceosomal complex + nucleolus + mitochondrion + integral component of peroxisomal membrane + endoplasmic reticulum membrane + eukaryotic translation initiation factor 3 complex + Arp2/3 protein complex + DNA polymerase III complex + Golgi transport complex + viral capsid + MKS complex + thylakoid membrane + cytochrome complex + ubiquitin ligase complex + core TFIIH complex + chromosome, centromeric region + cytosol + exodeoxyribonuclease VII complex + excinuclease repair complex + photosystem II reaction center + actin cytoskeleton + molybdopterin synthase complex + COPI vesicle coat + retromer complex + proton-transporting V-type ATPase, V1 domain + BBSome + intracellular membrane-bounded organelle + WASH complex + protein phosphatase type 2A complex + origin recognition complex + extracellular space + cell wall + mitochondrial outer membrane + signal peptidase complex + voltage-gated calcium channel complex + protein kinase CK2 complex + glycine cleavage complex + F-actin capping protein complex + peptidoglycan-based cell wall + 3-isopropylmalate dehydratase complex + riboflavin synthase complex + cytochrome b6f complex + thylakoid + prefoldin complex + clathrin coat of trans-Golgi network vesicle + clathrin coat of coated pit + GPI-anchor transamidase complex + oxoglutarate dehydrogenase complex + pyruvate dehydrogenase complex + nuclear chromosome + condensin complex + DNA replication factor C complex + DNA-directed RNA polymerase III complex + transcription factor TFIID complex + anaphase-promoting complex + mitochondrial respiratory chain complex III + mitochondrial ribosome + peroxisome + signal recognition particle, endoplasmic reticulum targeting + proteasome activator complex + formate dehydrogenase complex + polyphosphate kinase complex + Holliday junction helicase complex + bacterial-type flagellum basal body, distal rod, L ring + bacterial-type flagellum basal body, distal rod, P ring + bacterial-type flagellum basal body, MS ring + photosystem + Cdc73/Paf1 complex + TRAPP complex + checkpoint clamp complex + extracellular matrix + Ctf18 RFC-like complex + motile cilium + tRNA (m1A) methyltransferase complex + tricarboxylic acid cycle enzyme complex + succinate dehydrogenase complex + histone acetyltransferase complex + exocyst + ribonuclease MRP complex + nuclear exosome (RNase complex) + vacuolar proton-transporting V-type ATPase, V1 domain + mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) + mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) + THO complex part of transcription export complex + proteasome complex + gamma-tubulin complex + proteinaceous extracellular matrix + nuclear origin of replication recognition complex + DNA-directed RNA polymerase II, core complex + transcription factor TFIIA complex + transcription factor TFIIF complex + U1 snRNP + small nucleolar ribonucleoprotein complex + mitochondrial envelope + mitochondrial outer membrane translocase complex + mitochondrial inner membrane presequence translocase complex + mitochondrial respiratory chain complex IV + mitochondrial intermembrane space + mitochondrial matrix + signal recognition particle receptor complex + endoplasmic reticulum lumen + Golgi apparatus + fatty acid synthase complex + cytoskeleton + microtubule associated complex + gamma-tubulin ring complex + Gram-negative-bacterium-type cell wall + bacterial-type flagellum hook + bacterial-type flagellum basal body, distal rod + vacuolar proton-transporting V-type ATPase complex + viral envelope + CCR4-NOT complex + integral component of Golgi membrane + integral component of endoplasmic reticulum membrane + protein phosphatase 4 complex + ribonuclease P complex + preribosome, small subunit precursor + bacterial-type flagellum basal body, rod + Smc5-Smc6 complex + glutamyl-tRNA(Gln) amidotransferase complex + intraciliary transport particle A + BLOC-1 complex + Sec62/Sec63 complex + integral component of thylakoid membrane + cullin-RING ubiquitin ligase complex + ribonuclease H2 complex + SMN complex + proton-transporting two-sector ATPase complex, catalytic domain + Mpp10 complex + SMN-Sm protein complex + SAGA-type complex + FANCM-MHF complex + Ragulator complex + U2AF + ATG1/ULK1 kinase complex + CST complex + protein binding + ATP binding + catalytic activity + oxidoreductase activity + calcium ion binding + nucleic acid binding + DNA binding + protein kinase activity + hydrolase activity + zinc ion binding + RNA binding + structural constituent of ribosome + ATPase activity + transcription factor activity, sequence-specific DNA binding + GTP binding + transporter activity + ion channel activity + methyltransferase activity + metal ion binding + flavin adenine dinucleotide binding + microtubule motor activity + nucleotide binding + hydrolase activity, hydrolyzing O-glycosyl compounds + microtubule binding + pyridoxal phosphate binding + transferase activity, transferring glycosyl groups + ubiquitin-protein transferase activity + GTPase activity + electron carrier activity + heme binding + serine-type endopeptidase activity + aminoacyl-tRNA ligase activity + N-acetyltransferase activity + oxidoreductase activity, acting on the CH-CH group of donors + NAD binding + iron-sulfur cluster binding + iron ion binding + magnesium ion binding + metalloendopeptidase activity + sequence-specific DNA binding + NAD+ ADP-ribosyltransferase activity + transferase activity + 2 iron, 2 sulfur cluster binding + peptidyl-prolyl cis-trans isomerase activity + serine-type peptidase activity + pseudouridine synthase activity + transferase activity, transferring acyl groups other than amino-acyl groups + motor activity + hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds + phosphatidylinositol binding + ATPase activity, coupled to transmembrane movement of substances + DNA-directed 5'-3' RNA polymerase activity + metallopeptidase activity + transferase activity, transferring phosphorus-containing groups + kinase activity + voltage-gated potassium channel activity + oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor + peptidase activity + FMN binding + oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen + transferase activity, transferring acyl groups + lyase activity + transaminase activity + thiol-dependent ubiquitinyl hydrolase activity + 4 iron, 4 sulfur cluster binding + FAD binding + aspartic-type endopeptidase activity + receptor activity + coenzyme binding + ice binding + NAD(P)+-protein-arginine ADP-ribosyltransferase activity + NADP binding + cysteine-type peptidase activity + protein dimerization activity + RNA methyltransferase activity + unfolded protein binding + protein tyrosine/serine/threonine phosphatase activity + cation transmembrane transporter activity + 3'-5' exonuclease activity + sulfuric ester hydrolase activity + nucleotidyltransferase activity + hydrolase activity, acting on ester bonds + protein tyrosine phosphatase activity + phosphoric diester hydrolase activity + cofactor binding + nuclease activity + NADH dehydrogenase (ubiquinone) activity + protein disulfide oxidoreductase activity + isomerase activity + sugar:proton symporter activity + phosphorelay sensor kinase activity + transmembrane transporter activity + endonuclease activity + galactosyltransferase activity + transferase activity, transferring alkyl or aryl (other than methyl) groups + magnesium ion transmembrane transporter activity + solute:proton antiporter activity + carbohydrate binding + structural molecule activity + copper ion binding + translation initiation factor activity + DNA-directed DNA polymerase activity + calcium-dependent cysteine-type endopeptidase activity + phosphorus-oxygen lyase activity + nucleobase-containing compound kinase activity + acyl-CoA dehydrogenase activity + cytochrome-c oxidase activity + potassium channel activity + sulfotransferase activity + hydrogen ion transmembrane transporter activity + RNA polymerase II transcription factor activity, sequence-specific DNA binding + DNA helicase activity + damaged DNA binding + helicase activity + protein transporter activity + rRNA binding + 3-hydroxyacyl-CoA dehydrogenase activity + small protein activating enzyme activity + drug transmembrane transporter activity + antiporter activity + tRNA dihydrouridine synthase activity + translation elongation factor activity + peptide-methionine (S)-S-oxide reductase activity + oxidoreductase activity, acting on NAD(P)H + sigma factor activity + mismatched DNA binding + metal ion transmembrane transporter activity + aminopeptidase activity + transposase activity + phosphotransferase activity, alcohol group as acceptor + ligase activity, forming aminoacyl-tRNA and related compounds + threonine-type endopeptidase activity + GTPase activator activity + N-methyltransferase activity + ammonium transmembrane transporter activity + oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor + oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen + serine-type carboxypeptidase activity + sialyltransferase activity + proton-transporting ATP synthase activity, rotational mechanism + actin binding + DNA topoisomerase type II (ATP-hydrolyzing) activity + protein serine/threonine kinase activity + signal transducer activity + sulfate transmembrane transporter activity + intramolecular transferase activity, phosphotransferases + tRNA binding + 3',5'-cyclic-nucleotide phosphodiesterase activity + extracellular ligand-gated ion channel activity + transferase activity, transferring pentosyl groups + phosphatase activity + manganese ion binding + peptide-methionine (R)-S-oxide reductase activity + metallocarboxypeptidase activity + phosphogluconate dehydrogenase (decarboxylating) activity + intramolecular transferase activity + NAD+ binding + DNA topoisomerase activity + acetyl-CoA carboxylase activity + thiol-dependent ubiquitin-specific protease activity + oxidoreductase activity, acting on CH-OH group of donors + transferase activity, transferring hexosyl groups + ligase activity + histone-lysine N-methyltransferase activity + chaperone binding + DNA ligase (ATP) activity + adenylate kinase activity + monooxygenase activity + ATP-dependent helicase activity + amino acid transmembrane transporter activity + molybdenum ion binding + cation binding + translation release factor activity + mannosyl-oligosaccharide 1,2-alpha-mannosidase activity + antioxidant activity + oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor + oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor + nucleoside-triphosphate diphosphatase activity + recombinase activity + glucose-6-phosphate dehydrogenase activity + glutathione peroxidase activity + phosphoglycerate mutase activity + tRNA (guanine-N7-)-methyltransferase activity + metalloexopeptidase activity + CoA-transferase activity + fatty-acyl-CoA binding + aminoacyl-tRNA editing activity + acid phosphatase activity + carbonate dehydratase activity + MAP kinase activity + calcium-dependent phospholipid binding + acetylglucosaminyltransferase activity + nickel cation binding + phosphatidylinositol phosphate kinase activity + phosphotransferase activity, phosphate group as acceptor + dipeptidase activity + racemase and epimerase activity, acting on carbohydrates and derivatives + thiamine pyrophosphate binding + intermembrane lipid transfer activity + glutamate-ammonia ligase activity + penicillin binding + oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor + phosphotransferase activity, for other substituted phosphate groups + hydrolase activity, hydrolyzing N-glycosyl compounds + nitronate monooxygenase activity + substrate-specific transmembrane transporter activity + ATP-dependent DNA helicase activity + endopeptidase activity + superoxide dismutase activity + hydrolase activity, acting on glycosyl bonds + cobalamin binding + transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer + mannosyltransferase activity + DNA-(apurinic or apyrimidinic site) lyase activity + ATP-dependent peptidase activity + inorganic diphosphatase activity + pyruvate kinase activity + scavenger receptor activity + 7S RNA binding + Ran GTPase binding + rRNA methyltransferase activity + oxidoreductase activity, acting on the CH-NH2 group of donors + hydroxymethyl-, formyl- and related transferase activity + potassium ion binding + glutathione hydrolase activity + quinone binding + ATPase activator activity + NAD+ kinase activity + coproporphyrinogen oxidase activity + glutathione synthase activity + RNA-DNA hybrid ribonuclease activity + exonuclease activity + nucleoside diphosphate kinase activity + glycine-tRNA ligase activity + phenylalanine-tRNA ligase activity + ARF guanyl-nucleotide exchange factor activity + Rho guanyl-nucleotide exchange factor activity + structural constituent of cell wall + inorganic phosphate transmembrane transporter activity + ferric iron binding + inositol-1,4,5-trisphosphate 3-kinase activity + S-adenosylmethionine-dependent methyltransferase activity + molybdate ion transmembrane transporter activity + hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides + deaminase activity + double-stranded DNA binding + single-stranded DNA binding + 3-hydroxyisobutyryl-CoA hydrolase activity + 6-phosphofructo-2-kinase activity + DNA primase activity + DNA topoisomerase type I activity + RNA-directed 5'-3' RNA polymerase activity + aminoacyl-tRNA hydrolase activity + peroxidase activity + phosphoglycerate kinase activity + triose-phosphate isomerase activity + valine-tRNA ligase activity + transcription factor binding + heme-copper terminal oxidase activity + heme transporter activity + glutamate synthase activity + hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances + ribosome binding + peroxiredoxin activity + uridylyltransferase activity + RNA polymerase II transcription cofactor activity + chromatin binding + 1,3-beta-D-glucan synthase activity + 3-deoxy-7-phosphoheptulonate synthase activity + N-acetyl-gamma-glutamyl-phosphate reductase activity + UDP-glucose 4-epimerase activity + ferrochelatase activity + fructose-bisphosphate aldolase activity + hydroxymethylbilane synthase activity + malate synthase activity + methylenetetrahydrofolate reductase (NAD(P)H) activity + ribonuclease activity + beta-galactosidase activity + ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor + arginine-tRNA ligase activity + isoleucine-tRNA ligase activity + uroporphyrinogen decarboxylase activity + voltage-gated chloride channel activity + lipid binding + fucosyltransferase activity + sodium:proton antiporter activity + P-P-bond-hydrolysis-driven protein transmembrane transporter activity + amino acid binding + carboxyl- or carbamoyltransferase activity + hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides + carboxy-lyase activity + carbon-sulfur lyase activity + ubiquitin protein ligase binding + ribonuclease T2 activity + protein homodimerization activity + serine-type exopeptidase activity + carbohydrate derivative binding + adenyl-nucleotide exchange factor activity + 1-alkyl-2-acetylglycerophosphocholine esterase activity + DNA ligase activity + catalase activity + glycerol-3-phosphate dehydrogenase [NAD+] activity + histone acetyltransferase activity + ribonuclease III activity + alpha-mannosidase activity + beta-N-acetylhexosaminidase activity + pantothenate kinase activity + phosphopyruvate hydratase activity + phosphoribosylamine-glycine ligase activity + thiosulfate sulfurtransferase activity + alanine-tRNA ligase activity + structural constituent of cytoskeleton + calcium:sodium antiporter activity + ATP:ADP antiporter activity + SNAP receptor activity + sarcosine oxidase activity + ferrous iron binding + 5'-nucleotidase activity + holo-[acyl-carrier-protein] synthase activity + excinuclease ABC activity + chromate transmembrane transporter activity + oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen + sulfurtransferase activity + hydro-lyase activity + protein kinase binding + fructose 1,6-bisphosphate 1-phosphatase activity + peptidoglycan binding + gamma-tubulin binding + actin filament binding + transcription cofactor activity + protein disulfide isomerase activity + 3-beta-hydroxy-delta5-steroid dehydrogenase activity + ATP phosphoribosyltransferase activity + CTP synthase activity + DNA ligase (NAD+) activity + IMP cyclohydrolase activity + adenylosuccinate synthase activity + aspartate kinase activity + dephospho-CoA kinase activity + diacylglycerol O-acyltransferase activity + tetrahydrofolylpolyglutamate synthase activity + glycerol-3-phosphate dehydrogenase activity + guanylate kinase activity + histone deacetylase activity + homogentisate 1,2-dioxygenase activity + indole-3-glycerol-phosphate synthase activity + malate dehydrogenase (decarboxylating) (NAD+) activity + methylenetetrahydrofolate dehydrogenase (NADP+) activity + orotidine-5'-phosphate decarboxylase activity + phosphoenolpyruvate carboxykinase activity + phosphoenolpyruvate carboxykinase (ATP) activity + phosphoribosylaminoimidazolecarboxamide formyltransferase activity + poly(ADP-ribose) glycohydrolase activity + ribose-5-phosphate isomerase activity + tRNA (guanine-N2-)-methyltransferase activity + methionine-tRNA ligase activity + galactose binding + O-methyltransferase activity + dipeptidyl-peptidase activity + 3,4-dihydroxy-2-butanone-4-phosphate synthase activity + methionine synthase activity + exodeoxyribonuclease VII activity + alternative oxidase activity + chlorophyllide a oxygenase [overall] activity + ion transmembrane transporter activity + symporter activity + site-specific DNA-methyltransferase (cytosine-N4-specific) activity + translation release factor activity, codon specific + oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor + hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides + hydrolase activity, acting on acid anhydrides + endodeoxyribonuclease activity, producing 5'-phosphomonoesters + purine nucleotide binding + cation-transporting ATPase activity + enzyme regulator activity + phosphoric ester hydrolase activity + ADP binding + electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity + IMP 5'-nucleotidase activity + ADP-dependent NAD(P)H-hydrate dehydratase activity + 3'-5'-exoribonuclease activity + rRNA (adenine-N6,N6-)-dimethyltransferase activity + DNA replication origin binding + transcription corepressor activity + double-stranded RNA binding + lysozyme activity + beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity + 2-isopropylmalate synthase activity + 3-dehydroquinate dehydratase activity + 3-dehydroquinate synthase activity + 3-isopropylmalate dehydratase activity + 6-phosphofructokinase activity + GMP synthase (glutamine-hydrolyzing) activity + UDP-glucose:glycoprotein glucosyltransferase activity + acetolactate synthase activity + acetate-CoA ligase activity + adenosylhomocysteinase activity + aspartate carbamoyltransferase activity + branched-chain-amino-acid transaminase activity + carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity + dihydrolipoyl dehydrogenase activity + 3-oxoacyl-[acyl-carrier-protein] synthase activity + galactokinase activity + glucokinase activity + glucose-6-phosphate isomerase activity + glucosylceramidase activity + glutamate N-acetyltransferase activity + glycine dehydrogenase (decarboxylating) activity + heme oxygenase (decyclizing) activity + histidinol dehydrogenase activity + hydroxymethylglutaryl-CoA reductase (NADPH) activity + methylmalonyl-CoA mutase activity + N,N-dimethylaniline monooxygenase activity + phosphoribosylaminoimidazolesuccinocarboxamide synthase activity + phosphoribosylanthranilate isomerase activity + phosphoribosylformylglycinamidine synthase activity + polygalacturonase activity + porphobilinogen synthase activity + prephenate dehydratase activity + protein histidine kinase activity + ribose phosphate diphosphokinase activity + shikimate 3-dehydrogenase (NADP+) activity + sulfate adenylyltransferase (ATP) activity + thioredoxin-disulfide reductase activity + L-threonine ammonia-lyase activity + thymidine kinase activity + glutamate-tRNA ligase activity + leucine-tRNA ligase activity + lysine-tRNA ligase activity + proline-tRNA ligase activity + serine-tRNA ligase activity + threonine-tRNA ligase activity + tryptophan-tRNA ligase activity + tryptophan synthase activity + uracil DNA N-glycosylase activity + uroporphyrinogen-III synthase activity + calcium channel activity + binding + 5S rRNA binding + UDP-glucose:hexose-1-phosphate uridylyltransferase activity + ubiquinol-cytochrome-c reductase activity + 3-hydroxyisobutyrate dehydrogenase activity + riboflavin kinase activity + potassium-transporting ATPase activity + 1-deoxy-D-xylulose-5-phosphate synthase activity + 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity + 5-amino-6-(5-phosphoribosylamino)uracil reductase activity + diaminopimelate decarboxylase activity + diaminopimelate epimerase activity + 4-hydroxy-tetrahydrodipicolinate reductase + formate dehydrogenase (NAD+) activity + [glutamate-ammonia-ligase] adenylyltransferase activity + leucyltransferase activity + lipid-A-disaccharide synthase activity + phospho-N-acetylmuramoyl-pentapeptide-transferase activity + polyphosphate kinase activity + four-way junction helicase activity + potassium ion transmembrane transporter activity + AMP binding + acetyltransferase activity + octanoyltransferase activity + oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors + glutathione gamma-glutamylcysteinyltransferase activity + hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines + hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines + aldehyde-lyase activity + acid-amino acid ligase activity + thiol oxidase activity + S-formylglutathione hydrolase activity + guanyl nucleotide binding + protein phosphatase regulator activity + polysaccharide binding + thiamine binding + cysteine desulfurase activity + G-protein beta/gamma-subunit complex binding + ubiquitin-ubiquitin ligase activity + identical protein binding + ATP-dependent 3'-5' DNA helicase activity + nutrient reservoir activity + violaxanthin de-epoxidase activity + oleate hydratase activity + S-(hydroxymethyl)glutathione dehydrogenase activity + NADPH binding + starch binding + succinate dehydrogenase activity + imidazoleglycerol-phosphate synthase activity + purinergic nucleotide receptor activity + mRNA binding + gamma-glutamylcyclotransferase activity + 1-pyrroline-5-carboxylate dehydrogenase activity + 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity + 3-methyl-2-oxobutanoate hydroxymethyltransferase activity + 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity + acetylglutamate kinase activity + adenylylsulfate kinase activity + amidophosphoribosyltransferase activity + argininosuccinate synthase activity + argininosuccinate lyase activity + arginyltransferase activity + aspartate-semialdehyde dehydrogenase activity + biotin synthase activity + chorismate synthase activity + citrate (Si)-synthase activity + cytidylate kinase activity + dihydrolipoyllysine-residue succinyltransferase activity + dihydroneopterin aldolase activity + 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity + fumarylacetoacetase activity + glutamate dehydrogenase (NAD+) activity + glutamate-cysteine ligase activity + glycerone kinase activity + glycylpeptide N-tetradecanoyltransferase activity + histidinol-phosphate transaminase activity + homoserine kinase activity + hydroxyacylglutathione hydrolase activity + hydroxymethylglutaryl-CoA synthase activity + imidazoleglycerol-phosphate dehydratase activity + phosphatidylinositol phospholipase C activity + isocitrate dehydrogenase (NADP+) activity + isocitrate lyase activity + ketol-acid reductoisomerase activity + methionine adenosyltransferase activity + endodeoxyribonuclease activity + alpha,alpha-trehalase activity + alpha-galactosidase activity + oligosaccharyl transferase activity + oxoglutarate dehydrogenase (succinyl-transferring) activity + pantoate-beta-alanine ligase activity + phosphatidylserine decarboxylase activity + phosphoribosyl-AMP cyclohydrolase activity + phosphoribosyl-ATP diphosphatase activity + phosphoserine phosphatase activity + O-phospho-L-serine:2-oxoglutarate aminotransferase activity + protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity + pyrroline-5-carboxylate reductase activity + pyruvate dehydrogenase (acetyl-transferring) activity + dihydrolipoyllysine-residue acetyltransferase activity + thiamine diphosphokinase activity + thiamine-phosphate diphosphorylase activity + thymidylate kinase activity + thymidylate synthase activity + triglyceride lipase activity + cysteine-tRNA ligase activity + histidine-tRNA ligase activity + tyrosine-tRNA ligase activity + tryptophan 2,3-dioxygenase activity + ureidoglycolate hydrolase activity + extracellular ATP-gated cation channel activity + GDP-dissociation inhibitor activity + inward rectifier potassium channel activity + voltage-gated calcium channel activity + copper ion transmembrane transporter activity + phospholipid binding + DNA-dependent ATPase activity + galactoside 2-alpha-L-fucosyltransferase activity + 4-alpha-hydroxytetrahydrobiopterin dehydratase activity + tRNA methyltransferase activity + protein methyltransferase activity + calcium- and calmodulin-responsive adenylate cyclase activity + 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity + CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity + GDP-mannose 4,6-dehydratase activity + RNA ligase activity + queuine tRNA-ribosyltransferase activity + protoheme IX farnesyltransferase activity + acetyl-CoA transporter activity + DNA-3-methyladenine glycosylase activity + N-acetylmuramoyl-L-alanine amidase activity + UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity + UDP-N-acetylmuramate dehydrogenase activity + cellulase activity + dTDP-4-dehydrorhamnose 3,5-epimerase activity + 4-hydroxy-tetrahydrodipicolinate synthase + inositol monophosphate 1-phosphatase activity + phosphomethylpyrimidine kinase activity + Type I site-specific deoxyribonuclease activity + hydrogen-translocating pyrophosphatase activity + polysaccharide transmembrane transporter activity + peptide transporter activity + N-acyltransferase activity + pyrophosphatase activity + glutaminyl-peptide cyclotransferase activity + oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor + oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water + magnesium chelatase activity + ligase activity, forming carbon-nitrogen bonds + phosphatase activator activity + protein kinase regulator activity + protein domain specific binding + 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity + heat shock protein binding + lipoyl(octanoyl) transferase activity + DNA polymerase activity + racemase activity, acting on amino acids and derivatives + 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity + alpha-L-arabinofuranosidase activity + transition metal ion binding + ER retention sequence binding + proton-transporting ATPase activity, rotational mechanism + undecaprenyl-diphosphatase activity + 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity + cobalt ion binding + 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity + serine-type aminopeptidase activity + cytidylyltransferase activity + palmitoyl hydrolase activity + phosphorelay response regulator activity + tRNA-intron endonuclease activity + alanine dehydrogenase activity + 6,7-dimethyl-8-ribityllumazine synthase activity + DNA clamp loader activity + 3-hydroxybutyrate dehydrogenase activity + 3-isopropylmalate dehydrogenase activity + 3-phosphoshikimate 1-carboxyvinyltransferase activity + 4-hydroxyphenylpyruvate dioxygenase activity + 5-aminolevulinate synthase activity + D-arabinono-1,4-lactone oxidase activity + methylated-DNA-[protein]-cysteine S-methyltransferase activity + FMN adenylyltransferase activity + GTP cyclohydrolase I activity + GTP cyclohydrolase II activity + IMP dehydrogenase activity + NAD+ synthase (glutamine-hydrolyzing) activity + UDP-N-acetylglucosamine diphosphorylase activity + aconitate hydratase activity + adenosine deaminase activity + phospholipid-translocating ATPase activity + adenosylmethionine decarboxylase activity + N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity + aminomethyltransferase activity + arylformamidase activity + biotin-[acetyl-CoA-carboxylase] ligase activity + cholinesterase activity + cystathionine beta-lyase activity + cysteine synthase activity + cytidine deaminase activity + diacylglycerol kinase activity + dihydrofolate reductase activity + dihydroorotase activity + dihydroorotate dehydrogenase activity + dihydroxy-acid dehydratase activity + dUTP diphosphatase activity + formate-tetrahydrofolate ligase activity + fumarate hydratase activity + glutaminase activity + glutamine-fructose-6-phosphate transaminase (isomerizing) activity + histidinol-phosphatase activity + holocytochrome-c synthase activity + isopentenyl-diphosphate delta-isomerase activity + phosphogluconate dehydratase activity + lactoylglutathione lyase activity + mannose-6-phosphate isomerase activity + mRNA guanylyltransferase activity + methylmalonate-semialdehyde dehydrogenase (acylating) activity + inositol-3-phosphate synthase activity + nicotinate-nucleotide diphosphorylase (carboxylating) activity + nitric-oxide synthase activity + ribonuclease P activity + deoxyribonuclease activity + alpha-L-fucosidase activity + dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity + orotate phosphoribosyltransferase activity + pantetheine-phosphate adenylyltransferase activity + phosphoglycerate dehydrogenase activity + phosphoribosylformylglycinamidine cyclo-ligase activity + phosphoribosylglycinamide formyltransferase activity + polynucleotide adenylyltransferase activity + prenyltransferase activity + prephenate dehydrogenase (NADP+) activity + protein-arginine deiminase activity + calmodulin-dependent protein kinase activity + protein-L-isoaspartate (D-aspartate) O-methyltransferase activity + pyridoxamine-phosphate oxidase activity + ribokinase activity + transketolase activity + protein phosphatase inhibitor activity + endopeptidase inhibitor activity + signal recognition particle binding + guanyl-nucleotide exchange factor activity + Rab GDP-dissociation inhibitor activity + hormone activity + iron ion transmembrane transporter activity + monovalent cation:proton antiporter activity + calmodulin binding + chitin binding + tRNA-specific adenosine deaminase activity + protein prenyltransferase activity + pyridoxal kinase activity + gamma-glutamyl carboxylase activity + oxidized purine nucleobase lesion DNA N-glycosylase activity + 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity + 2-dehydropantoate 2-reductase activity + 4-hydroxy-2-oxovalerate aldolase activity + AMP nucleosidase activity + D-alanine-D-alanine ligase activity + UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity + UDP-N-acetylglucosamine 2-epimerase activity + UDP-N-acetylmuramate-L-alanine ligase activity + UDP-N-acetylmuramoylalanine-D-glutamate ligase activity + UDP-galactopyranose mutase activity + acetaldehyde dehydrogenase (acetylating) activity + alanine racemase activity + arsenate reductase (glutaredoxin) activity + beta-lactamase activity + cobalamin 5'-phosphate synthase activity + crossover junction endodeoxyribonuclease activity + dCTP deaminase activity + formyltetrahydrofolate deformylase activity + guanine deaminase activity + malate dehydrogenase (quinone) activity + nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity + prephenate dehydrogenase (NAD+) activity + serine O-acetyltransferase activity + serine-type D-Ala-D-Ala carboxypeptidase activity + tRNA nucleotidyltransferase activity + tetraacyldisaccharide 4'-kinase activity + urease activity + blue light photoreceptor activity + galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity + calcium:proton antiporter activity + p-aminobenzoyl-glutamate uptake transmembrane transporter activity + 2-keto-3-deoxygluconate:proton symporter activity + alanine:sodium symporter activity + chlorophyll binding + tRNA (cytosine-5-)-methyltransferase activity + rRNA (adenine) methyltransferase activity + malate dehydrogenase activity + protochlorophyllide reductase activity + oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor + oxidoreductase activity, acting on single donors with incorporation of molecular oxygen + oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen + oxidoreductase activity, oxidizing metal ions + transferase activity, transferring selenium-containing groups + triphosphoric monoester hydrolase activity + oxo-acid-lyase activity + carbon-nitrogen ligase activity, with glutamine as amido-N-donor + lipoate synthase activity + 6-phosphogluconolactonase activity + acetoacetyl-CoA reductase activity + protocatechuate 3,4-dioxygenase activity + glucosamine-1-phosphate N-acetyltransferase activity + tubulin N-acetyltransferase activity + cellulose binding + kynureninase activity + U5 snRNA binding + endoplasmic reticulum signal peptide binding + protein complex scaffold activity + pyridoxine 5'-phosphate synthase activity + inositol pentakisphosphate 2-kinase activity + cyclic-di-GMP binding + phosphate ion binding + histone binding + lipoprotein transporter activity + precorrin-2 dehydrogenase activity + molybdopterin cofactor binding + acyl-phosphate glycerol-3-phosphate acyltransferase activity + macromolecular complex binding + chalcone isomerase activity + UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity + chlorophyllase activity + inositol oxygenase activity + N-carbamoylputrescine amidase activity + ureidoglycolate lyase activity + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity + thymidylate synthase (FAD) activity + adenosylcobinamide-GDP ribazoletransferase activity + D-aminoacyl-tRNA deacylase activity + tRNA (guanine(37)-N(1))-methyltransferase activity + peptidase activity, acting on L-amino acid peptides + Lys48-specific deubiquitinase activity + 3-hydroxyanthranilate 3,4-dioxygenase activity + RNA 7-methylguanosine cap binding + RNA polymerase II transcription corepressor activity + galactosylceramide sulfotransferase activity + nucleoside binding + transcription coactivator activity + 1-acylglycerol-3-phosphate O-acyltransferase activity + 4-aminobutyrate transaminase activity + 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity + deoxyribodipyrimidine photo-lyase activity + alkylbase DNA N-glycosylase activity + DNA photolyase activity + GTP cyclohydrolase activity + L-serine ammonia-lyase activity + NADH dehydrogenase activity + UTP:glucose-1-phosphate uridylyltransferase activity + adenosine kinase activity + ATP-dependent RNA helicase activity + allantoicase activity + anthranilate phosphoribosyltransferase activity + anthranilate synthase activity + arginase activity + asparagine synthase (glutamine-hydrolyzing) activity + chorismate mutase activity + cyclic-nucleotide phosphodiesterase activity + cystathionine beta-synthase activity + L-seryl-tRNASec selenium transferase activity + 4-alpha-glucanotransferase activity + deoxyribose-phosphate aldolase activity + dihydropteroate synthase activity + dimethylallyltranstransferase activity + diphosphomevalonate decarboxylase activity + diphthine synthase activity + cysteine-type endopeptidase activity + fatty acid synthase activity + [acyl-carrier-protein] S-malonyltransferase activity + galactosylceramidase activity + glucosamine-6-phosphate deaminase activity + glutamate 5-kinase activity + glutamate-5-semialdehyde dehydrogenase activity + glutathione-disulfide reductase activity + hypoxanthine phosphoribosyltransferase activity + malic enzyme activity + methionyl-tRNA formyltransferase activity + mevalonate kinase activity + phenylalanine 4-monooxygenase activity + deoxyribonuclease II activity + dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity + phosphoadenylyl-sulfate reductase (thioredoxin) activity + phosphatidate cytidylyltransferase activity + phosphomannomutase activity + phosphoribosylaminoimidazole carboxylase activity + phosphorylase activity + polynucleotide 5'-phosphatase activity + polyribonucleotide nucleotidyltransferase activity + DNA-dependent protein kinase activity + phosphoprotein phosphatase activity + oxygen-dependent protoporphyrinogen oxidase activity + thyroxine 5'-deiodinase activity + aspartate-tRNA ligase activity + asparagine-tRNA ligase activity + uracil phosphoribosyltransferase activity + G-protein coupled receptor activity + histamine receptor activity + Rho GDP-dissociation inhibitor activity + cytokine activity + lipid transporter activity + neurotransmitter:sodium symporter activity + nucleoside transmembrane transporter activity + galactose transmembrane transporter activity + glucose transmembrane transporter activity + folic acid binding + beta-catenin binding + enzyme activator activity + primary amine oxidase activity + glycogen phosphorylase activity + RNA-dependent ATPase activity + tRNA guanylyltransferase activity + peptidyl-dipeptidase activity + secondary active sulfate transmembrane transporter activity + O-acyltransferase activity + 5'-3' exonuclease activity + 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity + dTDP-glucose 4,6-dehydratase activity + DNA topoisomerase (ATP-hydrolyzing) inhibitor activity + 2-dehydro-3-deoxygalactonokinase activity + 3-deoxy-manno-octulosonate cytidylyltransferase activity + L-aspartate oxidase activity + NAD(P)+ transhydrogenase activity + [protein-PII] uridylyltransferase activity + acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity + adenosylhomocysteine nucleosidase activity + alkyl hydroperoxide reductase activity + arginine N-succinyltransferase activity + choline dehydrogenase activity + cob(I)yrinic acid a,c-diamide adenosyltransferase activity + diaminohydroxyphosphoribosylaminopyrimidine deaminase activity + ethanolamine ammonia-lyase activity + glucose-1-phosphate thymidylyltransferase activity + glutamate racemase activity + glutamyl-tRNA reductase activity + isochorismatase activity + isochorismate synthase activity + mannonate dehydratase activity + methylthioadenosine nucleosidase activity + lytic transglycosylase activity + nitrite reductase [NAD(P)H] activity + phosphatidylglycerophosphatase activity + phosphoenolpyruvate carboxylase activity + phosphoglucosamine mutase activity + phosphoglycolate phosphatase activity + phosphopentomutase activity + phosphoribulokinase activity + protein-N(PI)-phosphohistidine-sugar phosphotransferase activity + protein-glutamate methylesterase activity + quinolinate synthetase A activity + rRNA (guanine-N2-)-methyltransferase activity + succinate-semialdehyde dehydrogenase [NAD(P)+] activity + succinyl-diaminopimelate desuccinylase activity + N-succinylarginine dihydrolase activity + thiamine-phosphate kinase activity + uridylate kinase activity + plastoquinol--plastocyanin reductase activity + L,L-diaminopimelate aminotransferase activity + disulfide oxidoreductase activity + ferrous iron transmembrane transporter activity + gluconate transmembrane transporter activity + carbohydrate transmembrane transporter activity + urea transmembrane transporter activity + sodium-dependent phosphate transmembrane transporter activity + polyamine-transporting ATPase activity + ATPase-coupled sulfate transmembrane transporter activity + toxic substance binding + urocanate hydratase activity + nitrogenase activity + small conductance calcium-activated potassium channel activity + lipase activity + tRNA (adenine-N1-)-methyltransferase activity + copper chaperone activity + cyclin-dependent protein serine/threonine kinase regulator activity + galactonolactone dehydrogenase activity + oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor + oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor + oxidoreductase activity, acting on the CH-NH group of donors + oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor + oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen + carotene 7,8-desaturase activity + oxidoreductase activity, acting on iron-sulfur proteins as donors + cellulose synthase (UDP-forming) activity + phosphotransferase activity, carboxyl group as acceptor + thiolester hydrolase activity + ammonia-lyase activity + racemase and epimerase activity, acting on amino acids and derivatives + intramolecular lyase activity + oxidoreductase activity, acting on the aldehyde or oxo group of donors + ribulose-bisphosphate carboxylase activity + precorrin-8X methylmutase activity + precorrin-6A reductase activity + TBP-class protein binding + U6 snRNA binding + nucleoside-diphosphatase activity + phosphatidylinositol N-acetylglucosaminyltransferase activity + catechol 2,3-dioxygenase activity + 4-hydroxybenzoate 3-monooxygenase activity + nitrile hydratase activity + muconate cycloisomerase activity + chloromuconate cycloisomerase activity + DNA N-glycosylase activity + polyamine binding + phosphatase binding + syntaxin binding + protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity + L-malate dehydrogenase activity + DNA polymerase processivity factor activity + snoRNA binding + trans-aconitate 2-methyltransferase activity + translation initiation factor binding + L-ascorbic acid binding + nucleosome binding + choline binding + preQ1 synthase activity + UMP kinase activity + ribonuclease D activity + mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity + hydroxyisourate hydrolase activity + glutamate-1-semialdehyde 2,1-aminomutase activity + adenosylcobinamide kinase activity + coenzyme F420-0 gamma-glutamyl ligase activity + precorrin-6A synthase (deacetylating) activity + tRNA 2-selenouridine synthase activity + acireductone synthase activity + crotonyl-CoA reductase activity + antisigma factor binding + lycopene beta cyclase activity + magnesium protoporphyrin IX methyltransferase activity + oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor + methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity + inositol tetrakisphosphate 1-kinase activity + cholestenol delta-isomerase activity + mRNA 5'-UTR binding + monosaccharide binding + threonine-phosphate decarboxylase activity + beta-tubulin binding + malonyl-CoA decarboxylase activity + pyruvate, phosphate dikinase activity + nitrous-oxide reductase activity + thiaminase activity + undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity + glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity + S-(hydroxymethyl)glutathione synthase activity + inositol-1,3,4-trisphosphate 6-kinase activity + inositol-1,3,4-trisphosphate 5-kinase activity + glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group + 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity + coenzyme F420 binding + nucleotide phosphatase activity, acting on free nucleotides + EF-Hand 1, calcium-binding site + EF-hand domain + Armadillo-like helical + Ankyrin repeat-containing domain + Tetratricopeptide-like helical domain + WD40/YVTN repeat-like-containing domain + Zinc finger, RING/FYVE/PHD-type + Protein kinase domain + Winged helix-turn-helix DNA-binding domain + Alpha/Beta hydrolase fold + Leucine-rich repeat + Immunoglobulin-like fold + Leucine-rich repeat domain, L domain-like + Serine/threonine-protein kinase, active site + Protein kinase, ATP binding site + WD40 repeat + Nucleotide-diphospho-sugar transferases + FAD/NAD(P)-binding domain + Aldolase-type TIM barrel + RmlC-like jelly roll fold + ABC transporter-like + WD40 repeat, conserved site + DnaJ domain + Ribonuclease H-like domain + Ion transport domain + Armadillo + Helicase, C-terminal + Pectin lyase fold + Ankyrin repeat + Short-chain dehydrogenase/reductase SDR + Rossmann-like alpha/beta/alpha sandwich fold + Methyltransferase FkbM + Pyridoxal phosphate-dependent transferase, subdomain 2 + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + HAD-like domain + Major facilitator superfamily + PH domain-like + DEAD/DEAH box helicase domain + Kinesin motor domain + Metallo-dependent phosphatase-like + Oxoglutarate/iron-dependent dioxygenase + ABC transporter, conserved site + ATPase, AAA-type, core + SAP domain + WW domain + Six-bladed beta-propeller, TolB-like + Galactose-binding domain-like + SET domain + C2 domain + Endonuclease/exonuclease/phosphatase + U box domain + GNAT domain + Histidine kinase-like ATPase, C-terminal domain + Mitochondrial carrier domain + AP2/ERF domain + RNA recognition motif domain + Kelch-type beta propeller + Mitochondrial substrate/solute carrier + Cyclic nucleotide-binding domain + Filamin/ABP280 repeat-like + ShKT domain + FKBP-type peptidyl-prolyl cis-trans isomerase domain + PPM-type phosphatase domain + Leucine rich repeat 5 + Calcineurin-like phosphoesterase domain, ApaH type + G-protein beta WD-40 repeat + Thiolase-like + AMP-dependent synthetase/ligase + Zinc finger, RING-type + Sel1-like repeat + Zinc finger C2H2-type + Small GTP-binding protein domain + Short-chain dehydrogenase/reductase, conserved site + Thioredoxin domain + Histidine phosphatase superfamily + MORN motif + Exostosin-like + Lysine methyltransferase + HSP20-like chaperone + Chlorophyll a/b binding protein domain + ABC transporter type 1, transmembrane domain MetI-like + Nucleotide-diphospho-sugar transferase + Alpha/beta hydrolase fold-1 + IPT domain + SNF2-related, N-terminal domain + Chlorophyll A-B binding protein + NADP-dependent oxidoreductase domain + Chromo domain + Alkaline phosphatase-like, alpha/beta/alpha + EGF-like, conserved site + SANT/Myb domain + Serine-threonine/tyrosine-protein kinase, catalytic domain + Cyclophilin-like domain + PDZ domain + Acyl-CoA dehydrogenase/oxidase, N-terminal + Signal transduction response regulator, receiver domain + Isopenicillin N synthase-like + Protein-tyrosine phosphatase-like + Zinc finger, RING-type, conserved site + Phytanoyl-CoA dioxygenase + von Willebrand factor, type A + Metallo-beta-lactamase + Zinc finger, CCCH-type + Poly(ADP-ribose) polymerase, catalytic domain + Acyl-CoA dehydrogenase/oxidase C-terminal + Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain + Ubiquitin-conjugating enzyme/RWD-like + Ribosomal protein S5 domain 2-type fold, subgroup + Beta-grasp domain + IQ motif, EF-hand binding site + Integrase-like, catalytic domain + Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase + Regulator of chromosome condensation, RCC1 + Aldehyde dehydrogenase domain + Phox homologous domain + Potassium channel domain + Aminotransferase, class I/classII + Histidine phosphatase superfamily, clade-1 + Aldehyde dehydrogenase N-terminal domain + Class I glutamine amidotransferase-like + Toll/interleukin-1 receptor homology (TIR) domain + Myosin head, motor domain + Sugar phosphate transporter domain + Zinc finger, PHD-type, conserved site + ABC transporter type 1, transmembrane domain + FAD dependent oxidoreductase + Glycosyltransferase 61 + NAD(P)-binding domain + Acyl-CoA oxidase/dehydrogenase, central domain + Ubiquitin domain + ATP-grasp fold, subdomain 1 + DnaJ domain, conserved site + CRAL-TRIO lipid binding domain + GTP binding domain + Kinesin motor domain, conserved site + Pleckstrin homology domain + Glutathione S-transferase, N-terminal + Tubulin-tyrosine ligase/Tubulin polyglutamylase + 6-phosphogluconate dehydrogenase, domain 2 + Crotonase superfamily + Sperm-tail PG-rich repeat + Zinc finger, CCHC-type + Ubiquitin-conjugating enzyme E2 + Forkhead-associated (FHA) domain + Pentatricopeptide repeat + UbiB domain + Nucleophile aminohydrolases, N-terminal + Zinc finger, PHD-finger + START-like domain + Tetratricopeptide repeat + Amidohydrolase-related + High mobility group box domain + Reverse transcriptase, RNA-dependent DNA polymerase + Methyltransferase type 11 + NUDIX hydrolase domain + AMP-binding, conserved site + Zinc finger, RanBP2-type + P22 tailspike C-terminal domain-like + PAS domain + GAF domain-like + Amino acid transporter, transmembrane domain + Transcription factor, GTP-binding domain + EamA domain + BTB/POZ domain + Peptidase C19, ubiquitin carboxyl-terminal hydrolase + Aspartic peptidase domain + Pseudouridine synthase, RsuA/RluB/C/D/E/F + DHS-like NAD/FAD-binding domain + Antifreeze protein, type I + PIN domain-like + tRNA (guanine-N1-)-methyltransferase, N-terminal + K Homology domain, type 1 + Small GTPase superfamily + Radical SAM + NAD:arginine ADP-ribosyltransferase, ART + Ubiquitin-associated domain + ATPase, AAA-type, conserved site + TonB-dependent receptor, beta-barrel + Tryptophan synthase beta subunit-like PLP-dependent enzyme + Alcohol dehydrogenase, C-terminal + Ribokinase-like + Rhodanese-like domain + Methyltransferase domain + BRCT domain + OTU domain + Sulfatase, N-terminal + CS domain + ATP-dependent RNA helicase DEAD-box, conserved site + Dual specificity phosphatase, catalytic domain + NAD-dependent epimerase/dehydratase + Aminotransferase class-III + Rieske [2Fe-2S] iron-sulphur domain + Alcohol dehydrogenase, N-terminal + FAD-binding domain + Solute-binding protein family 5 domain + Bestrophin/UPF0187 + Integrase, catalytic core + LysR, substrate-binding + P-type ATPase, cytoplasmic domain N + Cytochrome b5-like heme/steroid binding domain + Thioredoxin, conserved site + AMP-binding enzyme, C-terminal domain + Cytochrome c-like domain + Receptor L-domain + Amine oxidase + Glycosyl transferase, family 8 + Potassium channel, voltage-dependent, EAG/ELK/ERG + TonB-dependent receptor, plug domain + Alpha-ketoglutarate-dependent dioxygenase AlkB-like + Nucleotide-sugar transporter + Signal transduction histidine kinase-related protein, C-terminal + Glycosyltransferase 2-like + WWE domain + Metal-dependent hydrolase, composite domain + Rab-GTPase-TBC domain + Sterile alpha motif domain + Heat shock protein 70 family + Palmitoyltransferase, DHHC domain + Metallopeptidase, catalytic domain + Protein-tyrosine phosphatase, active site + Aldo/keto reductase + Peptidase S8/S53 domain + Major facilitator, sugar transporter-like + Fatty acid desaturase domain + Ribosomal protein L2 domain 2 + ADF-H/Gelsolin-like domain + Oxidoreductase FAD/NAD(P)-binding + P-type ATPase + Homeobox domain + Glycosyltransferase, DXD sugar-binding motif + FMN-binding split barrel + JmjC domain + Aminoacyl-tRNA synthetase, class I, conserved site + Aminoglycoside phosphotransferase + DNA methylase, N-6 adenine-specific, conserved site + Glycosyl transferase, family 31 + Transcription regulator HTH, LysR + Mitochondrial carrier protein + Aminoacyl-tRNA synthetase, class Ia + Cyclic nucleotide-binding, conserved site + Dynein heavy chain domain + Mpv17/PMP22 + Calycin + Sodium/calcium exchanger membrane region + Biotin/lipoyl attachment + Beta-lactamase-related + Cyclin-like + LVIVD + Cation/H+ exchanger + Polycystin cation channel, PKD1/PKD2 + Glutathione S-transferase, C-terminal + RNA-binding S4 domain + ABC transporter, FecCD/TroCD-like + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain + F-box domain + Peptidase M20 + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 + Aminoacyl-tRNA synthetase, class Ia, anticodon-binding + Phosphopantetheine binding ACP domain + C-type lectin-like/link domain + 2Fe-2S ferredoxin-type iron-sulfur binding domain + Magnesium transporter NIPA + Histone deacetylase domain + Voltage-dependent L-type calcium channel, IQ-associated domain + tRNA/rRNA methyltransferase, SpoU type + Kelch repeat type 1 + Dynein heavy chain, ATP-binding dynein motor region D5 + PUB domain + NHL repeat + Ubiquitin + Serine aminopeptidase, S33 + Bromodomain + Peptidase C2, calpain, catalytic domain + Adenylyl cyclase class-3/4/guanylyl cyclase + Adenylate kinase/UMP-CMP kinase + CBS domain + Aspartyl/asparaginy/proline hydroxylase + Ubiquitin specific protease, conserved site + SAM-dependent methyltransferase RsmB/NOP2-type + Glycosyl transferase, family 1 + Zinc finger, CXXC-type + Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase + Thiolase, N-terminal + Chromo domain, conserved site + P-type ATPase, phosphorylation site + Beta-ketoacyl synthase, N-terminal + Two pore domain potassium channel + Sugar transporter, conserved site + UVR domain + RNA (C5-cytosine) methyltransferase + TRAM/LAG1/CLN8 homology domain + Fungal lipase-like domain + Signal transduction histidine kinase, dimerisation/phosphoacceptor domain + Zinc finger, MYND-type + Dynein heavy chain, AAA module D4 + Glycosyl hydrolase, five-bladed beta-propellor domain + OmpA-like domain + 3'-5' exonuclease domain + Dynein heavy chain, domain-2 + Dynein heavy chain, hydrolytic ATP-binding dynein motor region D1 + Small GTPase superfamily, ARF/SAR type + Zn(2)-C6 fungal-type DNA-binding domain + Beta-ketoacyl synthase, C-terminal + Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain + Peptidase C1A, papain C-terminal + Tetratricopeptide repeat 2 + Nucleoside diphosphate kinase-like domain + Carbohydrate kinase PfkB + Glyoxalase/fosfomycin resistance/dioxygenase domain + Acyl-CoA dehydrogenase, conserved site + BTB/Kelch-associated + K homology domain-like, alpha/beta + Chaperonin Cpn60/TCP-1 family + Aquaporin-like + Agenet-like domain + Peptidase M16, N-terminal + Flavoprotein-like domain + Multi antimicrobial extrusion protein + THIF-type NAD/FAD binding fold + ABC transporter, permease + EGF-like domain, extracellular + Lipopolysaccharide-modifying protein + Dynein heavy chain, coiled coil stalk + Acriflavin resistance protein + Aminotransferase class V domain + Macrocin-O-methyltransferase + Hexapeptide repeat + tRNA-dihydrouridine synthase + Tr-type G domain, conserved site + CoA-transferase family III domain + CobW/HypB/UreG, nucleotide-binding domain + DNA-binding HTH domain, TetR-type + Peptide methionine sulphoxide reductase MsrA + Cysteine peptidase, cysteine active site + CAP Gly-rich domain + S1 domain + HECT domain + Alpha/beta hydrolase fold-3 + FAS1 domain + Fatty acid hydroxylase + Streptococcal non-M secreted SibA + Heat shock protein 70, conserved site + Thiolase, C-terminal + Peptidase S54, rhomboid domain + PAN/Apple domain + HAD hydrolase, subfamily IA + Adenylate kinase, conserved site + Thioesterase domain + Rubisco LSMT, substrate-binding domain + 3-hydroxyacyl-CoA dehydrogenase, NAD binding + Calponin homology domain + S-adenosyl-L-methionine-dependent methyltransferase + PLP-binding barrel + Galactose oxidase, beta-propeller + FG-GAP repeat + Isoprenoid synthase domain + Polyketide cyclase SnoaL-like domain + GroEL-like equatorial domain + FAD/NAD-linked reductase, dimerisation domain + 4Fe-4S ferredoxin, iron-sulphur binding, conserved site + Zinc finger, CW-type + Glycoside hydrolase-type carbohydrate-binding + Ammonium transporter AmtB-like domain + Helicase-associated domain + Phosphoglycerate/bisphosphoglycerate mutase, active site + NUDIX hydrolase, conserved site + Tubulin/FtsZ, GTPase domain + Crontonase, C-terminal + Dynamin superfamily + CoA-transferase family III + Peptidase S9, prolyl oligopeptidase, catalytic domain + Proteasome, subunit alpha/beta + Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site + Anoctamin + Transmembrane protein TauE-like + Glycoside hydrolase, family 7 + Glycoside hydrolase, family 5 + Glutamine amidotransferase + PLC-like phosphodiesterase, TIM beta/alpha-barrel domain + Glycoside hydrolase, family 3, N-terminal + ABC-2 type transporter + Reverse transcriptase domain + ATPase, dynein-related, AAA domain + Aldehyde dehydrogenase, cysteine active site + Zinc finger, RING-CH-type + Enolase C-terminal domain-like + Leucine-binding protein domain + SGNH hydrolase-type esterase domain + Glycosyl transferase family 29 + CUB domain + Peptidase M20, dimerisation domain + Fumarylacetoacetase, C-terminal-related + Cytochrome P450 + Carbon-nitrogen hydrolase + NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit + Ferritin-related + Peptidase S10, serine carboxypeptidase + Phosphopantetheine attachment site + DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site + Plastid lipid-associated protein/fibrillin conserved domain + Hemolysin-type calcium-binding conserved site + HIT-like domain + VPS9 domain + Pentapeptide repeat + ADP-ribosylation factor-like 2-binding protein, domain + Histone deacetylase superfamily + SNARE associated Golgi protein + Dynein heavy chain, domain-1 + Aspartic peptidase, active site + Transketolase-like, pyrimidine-binding domain + Inosine triphosphate pyrophosphatase-like + SPRY domain + TauD/TfdA-like domain + Actin family + Endoribonuclease L-PSP/chorismate mutase-like + Cold-shock protein, DNA-binding + Peptidase C2, calpain family + Arf GTPase activating protein + Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal + Thiolase + Flavoprotein pyridine nucleotide cytochrome reductase + Hedgehog protein, Hint domain + Glycoside hydrolase family 3 C-terminal domain + Formin, FH2 domain + Tyrosine-protein kinase ephrin type A/B receptor-like + Phospholipase/carboxylesterase/thioesterase + Transmembrane protein TqsA-like + Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain + SLC26A/SulP transporter domain + 2Fe-2S ferredoxin, iron-sulphur binding site + Thioredoxin-like fold + C-type lectin-like + RNA polymerase sigma-70 region 2 + Choline transporter-like + Phosphoglycolate phosphatase, domain 2 + AsnC-type HTH domain + Aldehyde dehydrogenase, glutamic acid active site + ADP ribosyltransferase + TOPRIM domain + Peptidase M24 + Peptide methionine sulphoxide reductase MrsB + Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II + 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain + Beta-L-arabinofuranosidase, GH127 + Protein of unknown function DUF4326) + Neurotransmitter-gated ion-channel ligand-binding domain + Translation elongation factor EFTu-like, domain 2 + Enoyl-CoA hydratase/isomerase, conserved site + Isochorismatase-like + Exonuclease, phage-type/RecB, C-terminal + Peptidase S8, subtilisin, Ser-active site + Ubiquitin conserved site + PNPase/RNase PH domain + Aldo/keto reductase, conserved site + Sirtuin family + Phospholipid/glycerol acyltransferase + 50S ribosomal protein L30e-like + ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain + Integrase, catalytic domain + CbxX/CfqX + MCM domain + Amidase signature domain + OmpR/PhoB-type DNA-binding domain + Peptidase M16, C-terminal + Helicase/UvrB, N-terminal + Glycosyltransferase 34 + Glycine cleavage T-protein-like, N-terminal + Nucleotidyl transferase domain + Luciferase-like domain + 3-hydroxyacyl-CoA dehydrogenase, C-terminal + tRNA-dihydrouridine synthase, conserved site + Fibronectin type III + Nonaspanin (TM9SF) + RNA polymerase sigma-70 like domain + Chaperone DnaJ, C-terminal + FAD-binding, type 2, subdomain 1 + Haemolysin-type calcium-binding repeat + 6-phosphogluconate dehydrogenase, NADP-binding + ACT domain + Transcription factor CBF/NF-Y/archaeal histone domain + Polyketide synthase, ketoreductase domain + 4Fe-4S ferredoxin-type, iron-sulphur binding domain + FAD linked oxidase, N-terminal + Peptidase S1C + UBX domain + Glutaredoxin + Cyclin, N-terminal + Molybdopterin oxidoreductase + Integrase/recombinase, N-terminal + ENTH/VHS + Peptidase M14, carboxypeptidase A + Phosphoribosyltransferase domain + RecF/RecN/SMC, N-terminal + Bordetella uptake gene + GHMP kinase, C-terminal domain + Peptidase M3A/M3B catalytic domain + Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like + Peptidase M48 + Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding + Zinc/iron permease + PWWP domain + Peptidyl-prolyl cis-trans isomerase, PpiC-type + Helix-turn-helix, base-excision DNA repair, C-terminal + Alanine racemase/group IV decarboxylase, C-terminal + Transcription regulator AsnC/Lrp, ligand binding domain + Biotin carboxylase-like, N-terminal domain + Cation efflux protein + Tetracycline resistance protein TetA/multidrug resistance protein MdtG + D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain + PPM-type phosphatase, divalent cation binding + Histone-lysine N-methyltransferase DOT1 domain + Protein of unknown function UPF0301 + Elongation factor EFG, domain V-like + Cytochrome c oxidase-like, subunit I domain + Phosphatidylinositol 3-/4-kinase, catalytic domain + Oxidoreductase, N-terminal + Glutamine synthetase/guanido kinase, catalytic domain + Transcription regulator FadR/GntR, C-terminal + Pyrrolo-quinoline quinone repeat + FERM/acyl-CoA-binding protein, 3-helical bundle + Inositol monophosphatase-like + RING-type zinc-finger, LisH dimerisation motif + Patatin-like phospholipase domain + Amino acid/polyamine transporter I + GAF domain + Pentacotripeptide-repeat region of PRORP + DNA helicase Pif1-like + Aspartate/glutamate/uridylate kinase + Glycosyl transferase, family 25 + Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding + Saccharopine dehydrogenase, NADP binding domain + GroEL-like apical domain + Polyadenylate-binding protein/Hyperplastic disc protein + Mur ligase, central + PC-Esterase + Acetyl-CoA carboxylase + Pyridine nucleotide-disulphide oxidoreductase, class I, active site + Glycoside hydrolase family 47 + Homeobox, conserved site + IBR domain + Dehydrogenase, E1 component + Glycoside hydrolase family 31 + FYVE zinc finger + Dihydroxy-acid/6-phosphogluconate dehydratase + MarR-type HTH domain + UAA transporter + DNA methylase N-4/N-6 + LSM domain, eukaryotic/archaea-type + STAS domain + Band 7 domain + Glycine cleavage T-protein, C-terminal barrel domain + GDP-fucose protein O-fucosyltransferase + Cytidyltransferase-like domain + Mannose-6-phosphate receptor binding domain + Zinc finger, C2H2, APLF-like + Peptidase S24/S26A/S26B/S26C + Tubulin/FtsZ, 2-layer sandwich domain + Peptide chain release factor class I/class II + Protein of unknown function DUF3431 + Glutathione peroxidase + Antibiotic biosynthesis monooxygenase domain + Diacylglycerol acyltransferase + Sulfotransferase domain + Thiolase, conserved site + ClpA/B family + Voltage-gated potassium channel + Oxidoreductase, FAD-binding domain + Biotin carboxylase, C-terminal + TRAP transporter solute receptor DctP/TeaA + Anticodon-binding + Folate-biopterin transporter + ABC-transporter extension domain + DNA photolyase, N-terminal + Clp protease proteolytic subunit /Translocation-enhancing protein TepA + GntR, C-terminal + Aminotransferases, class-I, pyridoxal-phosphate-binding site + GYF-like domain + Heat shock protein 70kD, peptide-binding domain + Heat shock protein 70kD, C-terminal domain + NYN domain, limkain-b1-type + SecA DEAD-like, N-terminal + Cytochrome P450, conserved site + Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) + PUA domain + Gelsolin-like domain + Cytochrome b5, heme-binding site + Myb domain, plants + Proteasome component (PCI) domain + Sulfatase, conserved site + Beta-ketoacyl synthase, active site + tRNA (guanine-N-7) methyltransferase, Trmb type + Zinc finger, C3HC4 RING-type + Adenylate kinase, active site lid domain + Pseudouridine synthase, RluC/RluD, conserved site + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site + Transcription regulator HTH, GntR + Clp ATPase, C-terminal + Coenzyme A transferase family I + 2-oxo acid dehydrogenase, lipoyl-binding site + Heavy metal-associated domain, HMA + Tetrapyrrole methylase, subdomain 1 + Peptidase family A1 domain + Peptidase S28 + Carbonic anhydrase + Enolase N-terminal domain-like + WGR domain + Exonuclease, RNase T/DNA polymerase III + Nitroreductase-like + Alcohol dehydrogenase, zinc-type, conserved site + Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant + Dpy-30 motif + Tail specific protease + Pectinacetylesterase/NOTUM + Aspartic peptidase A1 family + Fibronectin type III-like domain + Aromatic-ring-hydroxylating dioxygenase, alpha subunit + Tetratricopeptide repeat 1 + MerR-type HTH domain + Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal + NADH:flavin oxidoreductase/NADH oxidase, N-terminal + Transketolase, C-terminal domain + Ubiquitin-conjugating enzyme, active site + Phosphatidylinositol-4-phosphate 5-kinase, core + HhH-GPD domain + Glycoside hydrolase, family 27 + Restriction/modification DNA-methylase + OB-fold nucleic acid binding domain, AA-tRNA synthetase-type + Peptidase S8, subtilisin-related + GPS motif + Adenylate kinase subfamily + DNA methylase, C-5 cytosine-specific, active site + FAD-linked oxidoreductase-like + Cro/C1-type helix-turn-helix domain + Mitogen-activated protein (MAP) kinase, conserved site + YjgF/YER057c/UK114 family + HRDC domain + Glucose-methanol-choline oxidoreductase, C-terminal + ATP-dependent Clp protease proteolytic subunit + Sulfotransferase + MobA-like NTP transferase + Histone H2A/H2B/H3 + Annexin repeat + Pyruvate carboxyltransferase + Anaphase-promoting complex subunit 4, WD40 domain + Ulp1 protease family, C-terminal catalytic domain + Acyl-CoA-binding protein, ACBP + Haem oxygenase-like, multi-helical + Lon, substrate-binding domain + ParB/Sulfiredoxin + Glycolipid transfer protein domain + L,D-transpeptidase catalytic domain + FCP1 homology domain + Pseudouridine synthase I, TruA, C-terminal + Cysteine peptidase, histidine active site + Cysteine peptidase, asparagine active site + Hexapeptide transferase, conserved site + DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal + Cys/Met metabolism, pyridoxal phosphate-dependent enzyme + SCP2 sterol-binding domain + C-5 cytosine methyltransferase + AIR synthase-related protein, C-terminal domain + Tubby, C-terminal + Nitronate monooxygenase + RNA polymerase sigma-70 + Orn/DAP/Arg decarboxylase 2, C-terminal + TRAP C4-dicarboxylate transport system permease DctM subunit + Protein of unknown function DUF3645 + Flavodoxin/nitric oxide synthase + Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site + Peptidase S26A, signal peptidase I + Ribosomal RNA methyltransferase FtsJ domain + Cytochrome c oxidase subunit I + Vacuolar protein sorting-associated protein 13, N-terminal domain + Sugar/inositol transporter + Phosphatidylinositol-4-phosphate 5-kinase, C-terminal + Domain of unknown function DUF1605 + Thiolase, active site + Penicillin-binding protein, transpeptidase + Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains + Fumarate lyase, N-terminal + Trypanosoma cruzi ribosomal protein P2-like + Glycosyl transferase, family 20 + Membrane associated eicosanoid/glutathione metabolism-like domain + Resolvase, N-terminal catalytic domain + Regulator of K+ conductance, N-terminal + 5'-Nucleotidase, C-terminal + Transglutaminase-like + Fumarate lyase, conserved site + UbiA prenyltransferase family + Glycoside hydrolase family 2, catalytic domain + Sec63 domain + Non-haem dioxygenase N-terminal domain + Solute carrier family 13 + DNA ligase, ATP-dependent, central + UvrD-like DNA helicase, C-terminal + Aminoacyl-tRNA synthetase, class II (D/K/N) + Zinc finger, PARP-type + RNA binding activity-knot of a chromodomain + Glutamine synthetase, catalytic domain + ATPase, alpha/beta subunit, nucleotide-binding domain, active site + Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain + Synaptobrevin + Cytidine and deoxycytidylate deaminase domain + Carotenoid oxygenase + Glucose-6-phosphate dehydrogenase, C-terminal + Major intrinsic protein + Conserved hypothetical protein CHP02466 + Peptidoglycan binding-like + Polyprenyl synthetase + GIY-YIG nuclease superfamily + Tetrapyrrole methylase + Methyltransferase small domain + Serine carboxypeptidase, serine active site + Exoribonuclease, phosphorolytic domain 1 + Transposase IS3/IS911family + BSD domain + Clathrin/coatomer adaptor, adaptin-like, N-terminal + Protein of unknown function DUF3638 + Integral membrane protein TerC + Glucose-methanol-choline oxidoreductase, N-terminal + Dienelactone hydrolase + Carboxylesterase, type B + Phosphoglycerate mutase 1 + GHMP kinase N-terminal domain + Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain + 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain + Aminotransferase class IV + (Uracil-5)-methyltransferase family + Orn/DAP/Arg decarboxylase 2, N-terminal + Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 + O-GlcNAc transferase, C-terminal + Fumarase/histidase, N-terminal + Macro domain + 3'5'-cyclic nucleotide phosphodiesterase + Alpha crystallin/Hsp20 domain + AhpD-like + DNA mismatch repair protein MutS, C-terminal + Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead + Glycosyltransferase subfamily 4-like, N-terminal domain + Threonyl/alanyl tRNA synthetase, SAD + Iron/zinc purple acid phosphatase-like C-terminal domain + Polyprenyl synthetase, conserved site + DSBA-like thioredoxin domain + Pyridine nucleotide-disulphide oxidoreductase, class-II + DENN domain + Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain + Flavin reductase like domain + Cupredoxin + Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain + Succinyl-CoA synthetase-like + RND efflux pump, membrane fusion protein, barrel-sandwich domain + Vacuolar protein sorting-associated protein 13, second N-terminal domain + Creatinase/Aminopeptidase P/Spt16, N-terminal + DNA helicase, ATP-dependent, RecQ type + PAS fold + Cupin 2, conserved barrel + Glycosyl hydrolase family 30, TIM-barrel domain + Peptidase M23 + FAD-dependent oxidoreductase 2, FAD binding domain + Transcription regulator IclR, N-terminal + Fumarate lyase family + Tic22-like + Uracil-DNA glycosylase-like + Phosphatidic acid phosphatase type 2/haloperoxidase + Phosphoesterase + G-patch domain + CDP-alcohol phosphatidyltransferase + Sec1-like protein + RNA polymerase Rpb1, domain 1 + Serine hydrolase FSH + Acyltransferase ChoActase/COT/CPT + Ubiquitin system component Cue + Nitroreductase + Peptidase C2, calpain, large subunit, domain III + BolA protein + UmuC domain + Ribonucleotide reductase large subunit, C-terminal + MHCK/EF2 kinase + Probable zinc-binding domain + Kinesin light chain + Outer membrane protein/outer membrane enzyme PagP, beta-barrel + Tetrapyrrole methylase, subdomain 2 + Glycosyl transferase, family 14 + Epoxide hydrolase-like + Aminotransferase, class-II, pyridoxal-phosphate binding site + Glucosamine/galactosamine-6-phosphate isomerase + Cold-shock conserved site + Superoxide dismutase, copper/zinc binding domain + DJ-1/PfpI + Phosphatidylinositol-4-phosphate 5-kinase, N-terminal domain + Domain of unknown function DUF1995 + Zeta toxin domain + NUDIX hydrolase + Nucleoside phosphorylase domain + Chaperonin TCP-1, conserved site + Pseudouridine synthase, RsuA/RluB/E/F, conserved site + Alkaline phosphatase D-related + Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain + PQ-loop repeat + RlpA-like protein, double-psi beta-barrel domain + Methylthiotransferase, N-terminal + tRNA-binding domain + Polymerase, nucleotidyl transferase domain + UspA + TLDc domain + DNA binding HTH domain, AraC-type + Chaperone tailless complex polypeptide 1 (TCP-1) + Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site + Cathepsin propeptide inhibitor domain (I29) + EH domain + FAD-linked oxidase, C-terminal + Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 + Rad60/SUMO-like domain + 2-oxoacid dehydrogenase acyltransferase, catalytic domain + PurM-like, N-terminal domain + Amino acid ABC transporter, permease protein, 3-TM domain + Peptidase S49 + Guanylate-binding protein, N-terminal + Glutamine amidotransferase type 2 domain + DNA topoisomerase, type IA, central + Gamma-glutamyltranspeptidase + HAD-superfamily hydrolase, subfamily IIA + Transketolase, N-terminal + RelA/SpoT + Cryptochrome/DNA photolyase, FAD-binding domain + Radical SAM, alpha/beta horseshoe + Tubulin, conserved site + Phenylacetic acid degradation-related domain + Peptidase M41 + Peptidase M16, zinc-binding site + BEACH domain + Phospholipid methyltransferase + HD domain + MaoC-like domain + HAT, C-terminal dimerisation domain + Peptidase M1, alanyl aminopeptidase, C-terminal + Cation efflux protein, cytoplasmic domain + AP complex, mu/sigma subunit + DNA topoisomerase, type IIA + V-ATPase proteolipid subunit C-like domain + MoaB/Mog domain + Methylglyoxal synthase-like domain + RNA polymerase Rpb1, domain 5 + AdipoR/Haemolysin-III-related + Snf7 family + Solute-binding protein family 3/N-terminal domain of MltF + Importin-beta, N-terminal domain + Peptidase M17, leucyl aminopeptidase, C-terminal + Fe-S cluster assembly domain + R3H domain + NADH:ubiquinone oxidoreductase intermediate-associated protein 30 + Pyruvate kinase, barrel + Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein + Domain of unknown function DUF4339 + RAP domain + PIH1 domain + Proprotein convertase, P + Carbohydrate/puine kinase, PfkB, conserved site + tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related + Tripartite ATP-independent periplasmic transporter, DctQ component + Heat shock factor (HSF)-type, DNA-binding + Adaptor protein ClpS, core + RNA polymerase Rpb1, domain 3 + Serine carboxypeptidases, histidine active site + Transcription factor IIS, N-terminal + Branched-chain amino acid ATP-binding cassette transporter, C-terminal + tRNA-guanine(15) transglycosylase-like + Peptidase M17, leucine aminopeptidase/peptidase B + DHBP synthase RibB-like alpha/beta domain + Hemingway/KIAA1430 + DNA-binding recombinase domain + Transposase, Tn5-like, core + Domain of unknown function DUF218 + DNA polymerase, Y-family, little finger domain + Membrane transport protein + [2Fe-2S]-binding + Pirin, N-terminal domain + DNA binding HTH domain, Fis-type + Phospholipase D-like domain + Cation-transporting P-type ATPase, N-terminal + HNH endonuclease + Coenzyme Q-binding protein COQ10, START domain + Glutamine synthetase, glycine-rich site + Alanine racemase, N-terminal + Transcription regulator HTH, AsnC-type, conserved site + JAB1/MPN/MOV34 metalloenzyme domain + Adenosine/AMP deaminase domain + Oxidoreductase, molybdopterin-binding domain + Protein of unknown function DUF1295 + Pistil-specific extensin-like protein + Bacteriophage lambda, GpA + Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site + Vacuolar protein sorting-associated protein 13, C-terminal + Semialdehyde dehydrogenase, NAD-binding + DapA-like + DNA-directed DNA polymerase, family A, palm domain + Crp-type HTH domain + Carboxylesterase type B, active site + UvrD/AddA helicase, N-terminal + DNA topoisomerase, type IIA, subunit A/C-terminal + Nucleoside diphosphate kinase + DNA-directed DNA polymerase, family B, multifunctional domain + Redoxin + Sulfatase-modifying factor enzyme + RNA polymerase Rpb2, domain 2 + ADC synthase + Aldose 1-/Glucose-6-phosphate 1-epimerase + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 + Putative 5-3 exonuclease + Peptidase S16, Lon proteolytic domain + Pyruvate kinase + Acetyl-CoA carboxylase, central domain + Maf-like protein + NADP transhydrogenase beta-like domain + Inorganic polyphosphate/ATP-NAD kinase, domain 1 + Inositol polyphosphate kinase + TSP type-3 repeat + Signal recognition particle, SRP54 subunit, GTPase domain + CAAX amino terminal protease + Formyl transferase, N-terminal + RNA polymerase, alpha subunit + Glycosyl transferase, family 51 + Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal + Glyceraldehyde/Erythrose phosphate dehydrogenase family + Domain of unknown function DUF21 + von Hippel-Lindau disease tumour suppressor, beta domain + Cytochrome b561, bacterial/Ni-hydrogenase + Transcriptional regulator MarR-type, conserved site + Acyl transferase + Phosphorylated CTD interacting factor 1, WW domain + Sigma-54 interaction domain, ATP-binding site 1 + Transposase DDE domain + E3-binding domain + Histidine triad (HIT) protein + Peptidase M16, middle/third domain + Sec7 domain + Peroxiredoxin-like FAM213/AAED1 + ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain + Biotin-binding site + Glycoside hydrolase, family 79 + Dbl homology (DH) domain + DNA topoisomerase, type IIA, central domain + DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta + Glutamyl/glutaminyl-tRNA synthetase + Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site + ClpA/B, conserved site 2 + SOUL haem-binding protein + Transcription regulator IclR, C-terminal + Ribonuclease H domain + GRIP domain + ATP-citrate lyase/succinyl-CoA ligase + APOBEC/CMP deaminase, zinc-binding + 6-phosphofructo-2-kinase + Doublecortin domain + Isopropylmalate dehydrogenase-like domain + Ornithine/DAP/Arg decarboxylase + Serine/threonine dehydratase, pyridoxal-phosphate-binding site + HEAT repeat + DNA topoisomerase, type IIA, subunit B, domain 2 + RND efflux pump, membrane fusion protein + Heavy-metal-associated, conserved site + Integration host factor (IHF)-like DNA-binding domain + Triosephosphate isomerase + Vesicle transport protein, Got1/SFT2-like + SLC41 divalent cation transporters, integral membrane domain + Peptide chain release factor + Ccc1 family + Outer membrane protein, bacterial + Glycosyl transferase, family 3 + Cytochrome P450, E-class, group I + RNA-dependent RNA polymerase, eukaryotic-type + Triosephosphate isomerase, active site + YqgF/RNase H-like domain + Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB + Thiolase, acyl-enzyme intermediate active site + Sec7 domain, alpha orthogonal bundle + Hedgehog signalling/DD-peptidase zinc-binding domain + Lupus La protein + Polyketide synthase, dehydratase domain + Proton-dependent oligopeptide transporter family + Arginine repressor C-terminal-like domain + Complex 1 LYR protein + NADH:cytochrome b5 reductase (CBR) + HD/PDEase domain + Peptidase S33 + Eukaryotic molybdopterin oxidoreductase + CHAT domain + GGDEF domain + Homoserine dehydrogenase, catalytic + Regulator of K+ conductance, C-terminal + Transcription regulator LuxR, C-terminal + Activator of Hsp90 ATPase, N-terminal + Clp, N-terminal + Bax inhibitor 1-related + ClpA/B, conserved site 1 + Flavodoxin-like + Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain + Chloride channel, core + Alpha-D-phosphohexomutase, conserved site + UDPGP family + Glycerophosphodiester phosphodiesterase domain + Zinc finger, GRF-type + Phosphoglycerate kinase + Peptidase M8, leishmanolysin + Protein of unknown function DUF2924 + Arc-type ribbon-helix-helix + Aspartyl/Asparaginyl-tRNA synthetase, class IIb + Alpha-D-phosphohexomutase, alpha/beta/alpha domain I + Ppx/GppA phosphatase + Peptidase S9A, prolyl oligopeptidase + TerB-like + DNA-directed RNA polymerase, subunit 2, domain 6 + Endoplasmic reticulum vesicle transporter, C-terminal + Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 + Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type + Citrate transporter-like domain + La-type HTH domain + MIT + Peptidase M1, membrane alanine aminopeptidase, N-terminal + Histone-like DNA-binding protein + ATP synthase subunit alpha-like domain + ArgE/DapE/ACY1/CPG2/YscS, conserved site + Methionyl/Leucyl tRNA synthetase + HTH ArsR-type DNA-binding domain + Fringe-like + Vacuolar protein sorting-associated protein 13, SHR-binding domain + Glyceraldehyde-3-phosphate dehydrogenase, type I + Phage portal protein, lambda family + Glyceraldehyde 3-phosphate dehydrogenase, active site + WD40-like Beta Propeller + EAL domain + Exoribonuclease, phosphorolytic domain 2 + SWEET sugar transporter + Uncharacterised protein family UPF0061 + HpcH/HpaI aldolase/citrate lyase domain + Putative RNA methylase domain + Cytochrome c oxidase-like subunit III + Formate/nitrite transporter + RNA polymerase sigma factor 54 interaction domain + YbaK/aminoacyl-tRNA synthetase-associated domain + GTP cyclohydrolase II + Pseudouridine synthase I, TruA, alpha/beta domain + Capsular polysaccharide synthesis + Phosphoglycerate kinase, N-terminal + DNA ligase, ATP-dependent, C-terminal + DNA ligase, ATP-dependent, N-terminal + RGS domain + Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type + Aminoacyl-tRNA synthetase, class Ic + C-type lectin, conserved site + XPG-I domain + XPG/Rad2 endonuclease + ADP-ribosylation/Crystallin J1 + Mur ligase, C-terminal + Tubulin + Type IIA DNA topoisomerase subunit A, alpha-helical domain + Ribosomal protein L4 domain + Methylthiotransferase + DNA glycosylase/AP lyase, H2TH DNA-binding + Glycoside hydrolase family 20, catalytic domain + Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain + COMM domain + Membrane insertase OXA1/ALB3/YidC + Ribonuclease T2-like + Peptidase C65, otubain + Aconitase/3-isopropylmalate dehydratase, swivel + Chloride channel, voltage gated + FATC domain + Bacterial surface antigen (D15) + Peptidase C69, dipeptidase A + Domain of unknown function DUF2431 + Electron transfer flavoprotein, alpha/beta-subunit, N-terminal + Glutaredoxin active site + S-adenosylmethionine-dependent methyltransferase + Peptidase S9A, N-terminal domain + Zinc finger, ZZ-type + Zinc finger, A20-type + Valine-tRNA ligase + Outer membrane protein beta-barrel + Ribosomal protein L5 domain + Glutaredoxin subgroup + Glucose-6-phosphate dehydrogenase, active site + Peptidase A8, signal peptidase II + Methylthiotransferase, conserved site + JmjN domain + Bacteriophage phiJL001, Gp84, N-terminal + Ribosomal protein L7Ae/L30e/S12e/Gadd45 + Oligopeptide/dipeptide ABC transporter, C-terminal + Ribosomal protein L3 + Malate synthase + WHEP-TRS domain + Paired amphipathic helix + MCM OB domain + NodB homology domain + Mur ligase, N-terminal catalytic domain + PIN domain + Protein ENHANCED DISEASE RESISTANCE 2, C-terminal + Protein of unknown function DUF393 + D-galactarate/Altronate dehydratase, C-terminal + SsuA/THI5-like + Cytochrome b561/ferric reductase transmembrane + Cytochrome c assembly protein + Ammonium transporter, conserved site + Pirin, C-terminal domain + Methylthioribose-1-phosphate isomerase-like, N-terminal domain + Protein of unknown function DUF4336 + Glutamate synthase domain + Squalene/phytoene synthase + Carbamoyl-phosphate synthase large subunit, CPSase domain + Strawberry notch, helicase C domain + Sugar isomerase (SIS) + RWD domain + Ergosterol biosynthesis ERG4/ERG24 + Ribosomal protein L1/ribosomal biogenesis protein + Peptidase S26A, signal peptidase I, lysine active site + Tip attachment protein J + Ubiquitin interacting motif + RNA polymerase sigma-70 region 3 + Glutathione peroxidase conserved site + TatD family + Ribosomal protein L10P + Ribulose-phosphate 3-epimerase-like + Zinc finger, Sec23/Sec24-type + Sec23/Sec24, trunk domain + Domain of unknown function DUF4116 + GTA TIM-barrel-like domain + Aspartate/ornithine carbamoyltransferase + TGS + Aconitase family, 4Fe-4S cluster binding site + Glucose-6-phosphate dehydrogenase + Inorganic pyrophosphatase + Adrenodoxin + Glutamate/acetylglutamate kinase + RNA polymerase Rpb2, domain 3 + ClpP, histidine active site + Chorismate-utilising enzyme, C-terminal + Sodium/solute symporter + UDP-glucose/GDP-mannose dehydrogenase, N-terminal + Ferrochelatase + Glucose-6-phosphate dehydrogenase, NAD-binding + Purple acid phosphatase, N-terminal + FeS cluster biogenesis + Cobalamin (vitamin B12)-binding domain + Ubiquitin fusion degradation protein Ufd1-like + Translation elongation factor, KOW-like + tRNA methyltransferase TRMD/TRM10-type domain + Alpha-D-phosphohexomutase, alpha/beta/alpha domain III + Alpha-D-phosphohexomutase, C-terminal + DNA topoisomerase, type IIA, conserved site + CLASP N-terminal domain + Transcription termination factor, mitochondrial/chloroplastic + Amidohydrolase + Signal transduction histidine kinase, phosphotransfer (Hpt) domain + E2F/DP family, winged-helix DNA-binding domain + Glucose/Sorbosone dehydrogenase + UDP-glucose 4-epimerase + Lactate/malate dehydrogenase, C-terminal + Pseudouridine synthase, TruD + Thiamine phosphate synthase/TenI + Helix-hairpin-helix motif + Potassium channel tetramerisation-type BTB domain + DNA methylase, adenine-specific + Pyrroline-5-carboxylate reductase, catalytic, N-terminal + Target SNARE coiled-coil homology domain + Alpha-mannosyltransferase + Carbohydrate kinase, FGGY, N-terminal + Carbohydrate kinase, FGGY, C-terminal + Chaperonin Cpn60 + ATP synthase, F1 complex, gamma subunit + Amidohydrolase 3 + Ribosomal protein L11, C-terminal + Phosphatidylinositol 3/4-kinase, conserved site + Na+/H+ exchanger + Methylenetetrahydrofolate reductase + Protein of unknown function DUF1538 + Peptidase C19, ubiquitin-specific peptidase, DUSP domain + Tex-like domain + K Homology domain, type 2 + Protein of unknown function DUF1499 + Protein of unknown function DUF1501 + Glutathione-dependent formaldehyde-activating enzyme/centromere protein V + DNA mismatch repair protein MutS, N-terminal + Cullin, N-terminal + Pseudouridine synthase, RsuA/RluB/E/F + ELO family + SHOCT domain + Vanillyl-alcohol oxidase, C-terminal subdomain 2 + Outer membrane efflux protein + Protein of unknown function DUF1275 + DNA recombination and repair protein Rad51-like, C-terminal + Glycosyl transferase, family 48 + Domain of unknown function DUF305 + Vps16, C-terminal + SWAP/Surp + RNA polymerase sigma-70 region 4 + AAA domain + Amino acid exporter protein, LeuE-type + Zinc finger, LIM-type + Uroporphyrinogen decarboxylase (URO-D) + Phospholipase B-like + Copper chaperone SCO1/SenC + Xylanase inhibitor, N-terminal + Translation elongation factor EFTu/EF1A, C-terminal + Adenosylhomocysteinase-like + 3-oxoacid CoA-transferase, subunit A + Isoleucine-tRNA ligase + Glycosyl transferase family 10 + SMCs flexible hinge + Variant SH3 domain + Inositol monophosphatase, metal-binding site + XPG N-terminal + Ribosomal protein L14P + Beta-hexosaminidase + ThiamineS/Molybdopterin converting factor subunit 1 + Sporulation-related domain + TonB-dependent receptor, conserved site + ATP-dependent DNA helicase RecQ, zinc-binding domain + EEIG1/EHBP1 N-terminal domain + Signal recognition particle, SRP54 subunit, M-domain + Integrase, DNA-binding domain + Metalloenzyme + Bacterial DNA polymerase III, alpha subunit + AP endonuclease 1 + Porphobilinogen deaminase, N-terminal + Proteasome beta-type subunit, conserved site + DNA ligase, ATP-dependent, conserved site + Gdt1 family + MotA/TolQ/ExbB proton channel + Enolase + NRAMP family + NAD/GMP synthase + SUI1 domain + Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal + Hemimethylated DNA-binding domain + Membrane transport protein MMPL domain + Ribosomal Proteins L2, RNA binding domain + Ribosomal protein L2, C-terminal + Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain + DNA mismatch repair protein MutS-like, N-terminal + DNA mismatch repair protein MutS, core + Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal + Nucleosome assembly protein (NAP) + Protein of unknown function DUF2460 + GTP1/OBG domain + Histone H2A + Transglycosylase SLT domain 1 + Transaldolase/Fructose-6-phosphate aldolase + PKD/REJ-like domain + Ribosomal protein S8 + RmlD-like substrate binding domain + CobQ/CobB/MinD/ParA nucleotide binding domain + Peptidase A22B, signal peptide peptidase + Inosine/uridine-preferring nucleoside hydrolase domain + Zn-dependent metallo-hydrolase, RNA specificity domain + Nitrite/Sulfite reductase ferredoxin-like domain + uDENN domain + 4'-phosphopantetheinyl transferase superfamily + PEP-utilising enzyme, mobile domain + Proline dehydrogenase domain + DegT/DnrJ/EryC1/StrS aminotransferase + Acyltransferase 3 + Cytochrome b/b6-like domain + Molybdenum cofactor sulfurase, C-terminal + Calcineurin-like phosphoesterase domain, lpxH type + Thymidylate synthase/dCMP hydroxymethylase domain + Polyketide cyclase/dehydrase + NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain + Peroxidase, active site + Heat shock protein Hsp90 family + Cytochrome P450, E-class, group IV + ClpP, Ser active site + Ribosomal protein S10 domain + LETM1-like + Signal recognition particle, SRP54 subunit, helical bundle + DNA topoisomerase, type IA, central region, subdomain 2 + Translation Initiation factor eIF- 4e-like + RNA polymerase sigma-70 region 1.2 + Na-Ca exchanger/integrin-beta4 + Surfeit locus 4 + HAMP domain + Cell division protein FtsZ, conserved site + Transporter-associated domain + Protein of unknown function DUF3110 + GrpE nucleotide exchange factor, coiled-coil + ENTH domain + Phosphoadenosine phosphosulphate reductase + DTW + Translation initiation factor IF- 2, domain 3 + Tyrosine/serine-protein phosphatase IphP-type + SRCR domain + Flagellar basal body rod protein, N-terminal + Decaprenyl diphosphate synthase-like + SUF system FeS cluster assembly, SufBD + UDP-glucose/GDP-mannose dehydrogenase, dimerisation + PEP-utilising enzyme, C-terminal + TRAF-like + ATPase, AFG1-like + Putative esterase + Notch domain + Ricin B, lectin domain + GATS-like ACT domain + Saccharopine dehydrogenase, C-terminal + Glycoside hydrolase family 1 + Ham1-like protein + Aconitase A/isopropylmalate dehydratase small subunit, swivel domain + Ribosomal protein S9 + Glycoside hydrolase family 16 + Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 + Syntaxin/epimorphin, conserved site + Protein of unknown function DUF2793 + Histone H3/CENP-A + Replication factor-A protein 1, N-terminal + FAD dependent oxidoreductase, central domain + Inositol monophosphatase, conserved site + Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 + Zinc finger, NHR/GATA-type + BRO1 domain + Peptidase S26A, signal peptidase I, conserved site + Zinc finger, CHC2-type + Glutathione synthase + Oligopeptide transport permease C-like, N-terminal domain + Thiosulphate sulfurtransferase, conserved site + Mu homology domain + Thiaminase-2/PQQC + Ribosomal protein L6, alpha-beta domain + Threonine synthase, N-terminal + PBP domain + DNA-directed RNA polymerase, RpoA/D/Rpb3-type + NADH:ubiquinone oxidoreductase + Methylmalonyl-CoA mutase, alpha/beta chain, catalytic + Translation elongation factor EFG/EF2, domain IV + Glutamine synthetase, beta-Grasp domain + Sec23/Sec24 beta-sandwich + Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding + Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain + Histidine phosphatase superfamily, clade-2 + Sodium/calcium exchanger protein + Pyridoxamine kinase/Phosphomethylpyrimidine kinase + Pterin-binding domain + Herpesvirus/Caudovirus protease domain + AIG1-type guanine nucleotide-binding (G) domain + Cryptochrome/DNA photolyase class 1 + Ribosomal protein L13 + GTP-binding protein, ribosome biogenesis, YsxC + NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site + Mib-herc2 + RNA polymerase, beta subunit, protrusion + RNA polymerase Rpb2, domain 7 + ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast + Carboxymuconolactone decarboxylase-like + Selenoprotein Sep15/SelM + Protein of unknown function DUF1800 + Pyridoxal phosphate-dependent decarboxylase + Domain of unknown function DUF814 + Peptidase M24, methionine aminopeptidase + CarD-like/TRCF domain + Ribosomal protein L18e/L15P + CDC48 domain 2-like + Ribonuclease III domain + Tyrosyl-DNA phosphodiesterase I + Axonemal dynein light chain + HAD-superfamily hydrolase, subfamily IIB + Ribosomal protein L2, domain 3 + Aspartate/homoserine dehydrogenase, NAD-binding + Development/cell death domain + Coagulation factor 5/8 C-terminal domain + Proteasome alpha-subunit, N-terminal domain + Initiation factor 2B-related + Phenylalanyl-tRNA synthetase + Alpha-D-phosphohexomutase, alpha/beta/alpha domain II + Alpha-D-phosphohexomutase superfamily + Mini-chromosome maintenance, conserved site + ADP/ATP carrier protein + Leucine rich repeat 4 + Diacylglycerol kinase, catalytic domain + Nucleoside phosphatase GDA1/CD39 + Villin/Gelsolin + RNA polymerase, beta subunit, conserved site + Peptide deformylase + Glycosyl hydrolase family 92 + CRIB domain + Transaldolase, active site + Ubiquitin-activating enzyme, catalytic cysteine domain + Homocysteine-binding domain + Hydantoinase/oxoprolinase + Brix domain + Trehalose-phosphatase + Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal + Glycosyl transferase, family 15 + SEC-C motif + Soluble ligand binding domain + Ribosomal protein S2 + Ribonuclease HII/HIII domain + Glycoside hydrolase family 27/36, conserved site + Mandelate racemase/muconate lactonizing enzyme, N-terminal domain + Cytochrome c oxidase, subunit III, 4-helical bundle + Nucleoporin FG repeat + Enolpyruvate transferase domain + Ribosomal protein S15 + Creatinase, N-terminal + DNA mismatch repair protein MutS, connector domain + Enolase, C-terminal TIM barrel domain + Enolase, N-terminal + Histone-like DNA-binding protein, conserved site + Sigma-54 interaction domain, conserved site + Ribosomal protein S10 + Chromate transporter + GrpE nucleotide exchange factor, head + Transcription elongation factor S-II, central domain + Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit + ATPase, F1/V1 complex, beta/alpha subunit, C-terminal + Cleft lip and palate transmembrane 1 + PAS fold-3 + SMP-30/Gluconolactonase/LRE-like region + Gamma-tubulin complex component protein + Mce/MlaD + Bacteriophage phiJL001, Gp84 + NADPH-dependent FMN reductase-like + Impact, N-terminal + IMP dehydrogenase/GMP reductase + Tyrosyl-DNA phosphodiesterase C-terminal domain + Histone H1-like nucleoprotein HC2 + MT-A70-like + Transmembrane Fragile-X-F-associated protein + Glycosyl transferase, family 28, C-terminal + Biopolymer transport protein ExbD/TolR + GrpE nucleotide exchange factor + Pyridoxamine 5'-phosphate oxidase, putative + LysM domain + Dihydrofolate reductase-like domain + Cobalamin (vitamin B12)-dependent enzyme, catalytic + Methyltransferase Ppm1/Ppm2/Tcmp + CCB3/YggT + Platelet-activating factor acetylhydrolase-like + Ribosomal RNA small subunit methyltransferase H + DNA-directed RNA polymerase, insert domain + Haem peroxidase, plant/fungal/bacterial + SbmA/BacA-like + Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain + Arginyl-tRNA synthetase, catalytic core domain + Endopeptidase, NLPC/P60 domain + Ribosomal protein L5, C-terminal + Pyruvate kinase, C-terminal + Alanyl-tRNA synthetase, class IIc, N-terminal + Cell division protein FtsZ, C-terminal + NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain + Xylanase inhibitor, C-terminal + Histidine biosynthesis + Citrate synthase active site + Gcp-like domain + Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain + Sialidases + Chaperonin Cpn60, conserved site + Phosphoribulokinase/uridine kinase + Poly(ADP-ribose) polymerase, regulatory domain + Protein of unknown function DUF1415 + IMP-specific 5-nucleotidase + DNA polymerase, palm domain + Glycoside hydrolase, family 76 + Basic-leucine zipper domain + Manganese/iron superoxide dismutase, C-terminal + Manganese/iron superoxide dismutase, binding site + Manganese/iron superoxide dismutase, N-terminal + Orotidine 5'-phosphate decarboxylase domain + Ribosomal protein L9, N-terminal + tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal + Ribosomal protein S19, superfamily + Thioredoxin + Glycoside hydrolase family 38, central domain + Ribosomal protein S15, bacterial-type + Putative transposase IS4/IS5 family + Ribosomal protein L22/L17 + Ribosomal protein L31 + Guanylate kinase/L-type calcium channel beta subunit + Multicopper oxidase, type 2 + Multicopper oxidase, type 3 + MIF4G-like, type 3 + Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site + Elongation factor P, C-terminal + Ribosomal protein L20 + Phage capsid + Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich + Ribosomal protein L4/L1e + Glycosyl hydrolases family 2, sugar binding domain + Ribokinase/fructokinase + Protein-tyrosine phosphatase, SIW14-like + Ubiquitin-activating enzyme E1, Cys active site + Molybdate-anion transporter + Golgi apparatus membrane protein TVP15 + AP endonuclease 1, binding site + Flagellar calcium-binding protein calflagin + Zinc finger, DksA/TraR C4-type + Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain + PITH domain + Ribosomal protein S2, bacteria/mitochondria/plastid + Homogentisate 1,2-dioxygenase + Lactonase, 7-bladed beta propeller + Clathrin adaptor, mu subunit + Dynamin central domain + Ribosomal protein S11 + Dephospho-CoA kinase + Peptidogalycan biosysnthesis/recognition + Sporulation stage V, protein S + Translation elongation factor EF1B/ribosomal protein S6 + Amino acid permease/ SLC12A domain + DHHA1 domain + NiFe hydrogenase-like + Neurolysin/Thimet oligopeptidase, N-terminal + ATP-dependent (S)-NAD(P)H-hydrate dehydratase + Myc-type, basic helix-loop-helix (bHLH) domain + Ribosomal protein S20 + Threonine synthase-like + Ribosomal protein S5, C-terminal + GRAM domain + Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B + N2227-like + Aminotransferase class-V, pyridoxal-phosphate binding site + DNA mismatch repair protein, C-terminal + Ribonucleotide reductase large subunit, N-terminal + Ribosomal protein S4/S9, N-terminal + Domain of unknown function DUF971 + W2 domain + Fido domain + Capsule polysaccharide biosynthesis + Ribonuclease T2, His active site 1 + Kringle + ABC-2 transporter + Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain + Batten's disease protein Cln3 + Acylneuraminate cytidylyltransferase + Cytochrome c, class IA/ IB + ApaG domain + Tubulin binding cofactor C-like domain + PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase + Porphobilinogen deaminase + 3-hydroxyacyl-CoA dehydrogenase, conserved site + Mitochondrial 18kDa protein + PPPDE putative peptidase domain + Zinc finger, UBR-type + WH2 domain + Ribosomal protein L7/L12, C-terminal + ATP phosphoribosyltransferase, catalytic domain + GTP-binding protein, orthogonal bundle domain + Ribosomal protein L7/L12, oligomerisation + Molybdopterin dehydrogenase, FAD-binding + Protein of unknown function DUF2358 + WHIM2 domain + ATP-dependent RNA helicase Ski2, C-terminal + Endonuclease III-like, conserved site-2 + KOW + Enolase, conserved site + Ribosome recycling factor domain + Phosphoenolpyruvate carboxykinase, ATP-utilising + Ribosomal protein L1, 3-layer alpha/beta-sandwich + FeS cluster insertion protein + TsaA-like domain + Phosphate acetyl/butaryl transferase + Sodium:dicarboxylate symporter + Phenylalanyl-tRNA synthetase, B3/B4 + Chorismate mutase, type II + N6 adenine-specific DNA methyltransferase, N-terminal domain + Endoplasmic reticulum oxidoreductin 1 + GYF domain + Ribosomal protein L21-like + YqaJ viral recombinase + Methioninyl-tRNA synthetase core domain + Mrp, conserved site + Prohead protease + Phospholipase D, N-terminal + TspO/MBR-related protein + GTP-binding protein LepA, C-terminal + Type II secretion system protein E + Histone deacetylase + Heat shock protein Hsp90, N-terminal + DNA gyrase B subunit, C-terminal + Carbamoyl-phosphate synthetase, large subunit oligomerisation domain + MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal + Aspartate kinase domain + Villin headpiece + S-adenosyl-L-homocysteine hydrolase, NAD binding domain + START domain + Ribosomal protein S12/S23 + Ureohydrolase + Pheophorbide a oxygenase + Peptidyl-tRNA hydrolase + Ribosomal protein L5, N-terminal + Peptidase S26A, signal peptidase I, serine active site + Adenylosuccinate synthetase + AICARFT/IMPCHase bienzyme + Aspartate/other aminotransferase + Uroporphiryn-III C-methyltransferase, conserved site + tRNA methyltransferase, Trm1 + Citrate synthase + Putative pre-16S rRNA nuclease + Class II aldolase/adducin N-terminal + Mechanosensitive ion channel MscS + Histidine triad, conserved site + FMN-dependent dehydrogenase + Ribosomal protein S17/S11 + FAD-dependent glycerol-3-phosphate dehydrogenase + 3-beta hydroxysteroid dehydrogenase/isomerase + GTP1/OBG, conserved site + Protein of unknown function DUF952 + Ribosomal protein S13 + Formamidopyrimidine-DNA glycosylase, catalytic domain + Exportin-1/Importin-beta-like + Protein of unknown function DUF3489 + Protein of unknown function DUF839 + UbiA prenyltransferase conserved site + 3-hydroxyisobutyrate dehydrogenase-related, conserved site + SecY/SEC61-alpha family + Polycystic kidney disease type 2 protein + Transcription regulator MerR, DNA binding + Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain + NIF system FeS cluster assembly, NifU, C-terminal + Ribosomal protein L25/L23 + Domain of unknown function DUF933 + Domain of unknown function DUF1214 + MCM N-terminal domain + EXS, C-terminal + Alpha-N-methyltransferase NTM1 + Squalene/phytoene synthase, conserved site + Cyclin PHO80-like + Protein of unknown function DUF900, hydrolase-like + Ribosomal RNA small subunit methyltransferase E + Smr domain + Ribosomal protein L13, bacterial-type + Glycosyltransferase family 92 + Translation elongation factor P/YeiP, central + Ribosomal protein L10e/L16 + DNA primase, catalytic core, N-terminal + DNA mismatch repair, conserved site + Ribonuclease T2, His active site 2 + Carbonic anhydrase, prokaryotic-like, conserved site + SH3 domain + ROK family + Thioesterase + RNA methyltransferase TrmA, active site + RNA methyltransferase TrmA, conserved site + Restriction endonuclease, type I, HsdR, N-terminal + GxGYxYP putative glycoside hydrolase, C-terminal + Ribosomal protein S7 domain + Parallel beta-helix repeat-2 + FIST domain, N-terminal + Peptidase C12, ubiquitin carboxyl-terminal hydrolase + Rho GTPase-activating protein domain + Histone H2A conserved site + Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase + Ribosomal protein L2, conserved site + Double-stranded RNA-binding domain + Actin-depolymerising factor homology domain + CO dehydrogenase flavoprotein, C-terminal + MacB-like periplasmic core domain + Tyrosine-protein kinase, active site + SOS response associated peptidase (SRAP) + Aromatic amino acid beta-eliminating lyase/threonine aldolase + 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB + Alanine-tRNA ligase, class IIc + Cytochrome c oxidase, subunit I, copper-binding site + Hydantoinase B/oxoprolinase + Domain of unknown function DUF2470 + Acetyl-CoA dehydrogenase-like C-terminal domain + L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase + Phosphate transporter + Ribosomal protein S14 + Syntaxin 6, N-terminal + Indoleamine 2,3-dioxygenase + Haem-binding uptake, Tiki superfamily, ChaN + Alpha-isopropylmalate/homocitrate synthase, conserved site + Deoxyribonuclease, TatD-related, conserved site + Hydantoinaseoxoprolinase, N-terminal + Poly(ADP-ribose) glycohydrolase + NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding + B3/B4 tRNA-binding domain + Beta-Casp domain + Phenol hydroxylase reductase + Kae1/TsaD family + Ribosomal protein S30Ae/sigma 54 modulation protein + Multicopper oxidase, copper-binding site + Disulphide bond formation protein DsbB-like domain + Ribosomal protein L2, bacterial/organellar-type + Alternative oxidase + PsbP family + DALR anticodon binding + CinA, C-terminal + UDP-glucose/GDP-mannose dehydrogenase + Copper type II, ascorbate-dependent monooxygenase-like, C-terminal + ABC transporter permease protein domain + Cytochrome C biogenesis protein, transmembrane domain + MIP18 family-like + Guanylate kinase + Metalloprotease TldD/PmbA + Manganese/iron superoxide dismutase + CTP synthase, N-terminal + NB-ARC + GTP-binding protein Obg/CgtA + Galactokinase galactose-binding domain + Peptidase S26 + Zinc finger, double-stranded RNA binding + Carbohydrate kinase, FGGY, conserved site + Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal + HTH-like domain + Coproporphyrinogen III oxidase, aerobic + NADH:ubiquinone oxidoreductase, 30kDa subunit + XK-related protein + Vps4 oligomerisation, C-terminal + Sulphur transport domain + Ribosomal protein S5, N-terminal + Acetyl-coenzyme A synthetase, N-terminal domain + APC10/DOC domain + Ribosomal protein S19/S15 + Cytochrome P450, B-class + Flavin amine oxidase + RNA polymerase Rpb1, domain 4 + Ribosomal protein L11, N-terminal + Chorismate mutase + PAS fold-4 + Mitochondrial inner membrane translocase subunit Tim17/Tim22/Tim23/peroxisomal protein PMP24 + NlpC/P60 family, putative phage cell wall peptidase + Transposase, IS4-like + FAD-binding, type 1 + Glycosyltransferase family 28, N-terminal domain + AICAR transformylase domain + Dynein light chain, type 1/2 + PIK-related kinase, FAT + Domain of unknown function DUF1601 + Thiamine pyrophosphate enzyme, C-terminal TPP-binding + Type II secretion system F domain + Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal + Serine-tRNA synthetase, type1, N-terminal + ATP synthase, F0 complex, subunit A + Fructose-bisphosphate aldolase, class-I + DNA polymerase A + NnrU domain + NusB/RsmB/TIM44 + Phosphoribosylglycinamide synthetase, C-domain + Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain + Transport-associated OB, type 2 + Domain of unknown function DUF1736 + ABC-type glycine betaine transport system, substrate-binding domain + Helitron helicase-like domain + tRNA synthetases class I, catalytic domain + DNA photolyase class 2, conserved site + YVTN beta-propeller repeat + DAHP synthetase, class II + SPX domain + Peptidase, FtsH + DNA methylase, N-4 cytosine-specific, conserved site + Domain of unknown function DUF1330 + Xanthine/uracil/vitamin C permease + Chalcone/stilbene synthase, C-terminal + Meckelin + ArgJ-like domain + Paraquat-inducible protein A + DNA methylase, C-5 cytosine-specific, conserved site + Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain + Kelch repeat type 2 + TPMT family + Oxidoreductase, C-terminal + Glycoside hydrolase family 31, N-terminal domain + Magnesium chelatase ChlI domain + Ribosomal protein S6 + Indole-3-glycerol phosphate synthase + CoA-binding + COX15/CtaA family + Protein arginine methyltransferase NDUFAF7 + P-type ATPase, subfamily IB + Bicarbonate transporter, C-terminal + GHMP kinase, ATP-binding, conserved site + Bromodomain, conserved site + Cation-transporting P-type ATPase, C-terminal + Malic enzyme, N-terminal domain + Malic enzyme, NAD-binding + Methyltransferase type 12 + DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat + HAD-superfamily phosphatase, subfamily IIIC + Translation initiation factor 3, C-terminal + Isocitrate/isopropylmalate dehydrogenase, conserved site + Flagellar basal-body/hook protein, C-terminal domain + NADH dehydrogenase ubiquinone Fe-S protein 4, mitochondrial + Membrane insertase YidC/Oxa1, C-terminal + Major intrinsic protein, conserved site + RNA-polymerase II-associated protein 3-like, C-terminal domain + G8 domain + Translation elongation factor EFTs/EF1B + Non-canonical purine NTP phosphatase/PRRC1 + Glutamate-ammonia ligase adenylyltransferase, repeated domain + 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III + Staphylococcal nuclease (SNase-like), OB-fold + MgtC/SapB/SrpB/YhiD family + Zinc finger, TRAF-type + UDP-glucose:Glycoprotein Glucosyltransferase + Hydroxyacylglutathione hydrolase, C-terminal domain + Ribosomal protein L15, bacterial-type + Ribosomal protein L14P, bacterial-type + ATP synthase, F1 complex, alpha subunit + Phosphoenolpyruvate carboxykinase, C-terminal + RNA-binding protein AU-1/Ribonuclease E/G + DEAD2 + Methionyl-tRNA synthetase + Periplasmic solute binding protein, ZnuA-like + Folylpolyglutamate synthetase, conserved site + Ribosomal S11, conserved site + Semialdehyde dehydrogenase, dimerisation domain + ATP:guanido phosphotransferase, catalytic domain + Porphobilinogen deaminase, C-terminal + Ribosome-binding factor A + Haem oxygenase-like + ERV/ALR sulfhydryl oxidase domain + ACT-like domain + Malate/L-lactate dehydrogenase-like + dUTPase-like + Domain of unknown function DUF892 + Transcription regulator Rrf2-type + Dihydroorotate dehydrogenase domain + DNA-directed RNA polymerase, beta subunit, external 1 domain + XPC-binding domain + Xylose isomerase-like, TIM barrel domain + Protein-export membrane protein SecD/SecF, bacterial + Protein of unknown function DUF4231 + Heat shock protein Hsp33 + Histone H4 + CSN8/PSMD8/EIF3K + Digestive organ expansion factor, predicted + Vps72/YL1, C-terminal + Mitochondrial fission protein ELM1-like + Adrenodoxin, iron-sulphur binding site + Thiamine pyrophosphate enzyme, central domain + Ribosomal protein L33 + Protein O-mannosyl-transferase, C-terminal four TM domain + Ribosomal protein S3, bacterial + Ribosomal protein L1, bacterial-type + Bromo adjacent homology (BAH) domain + Translation elongation factor EFTs/EF1B, dimerisation + DDT domain + Phosphodiester glycosidase + Leucyl/phenylalanyl-tRNA-protein transferase + UDP-glucuronosyl/UDP-glucosyltransferase + Glycerol-3-phosphate dehydrogenase, NAD-dependent + Pyridine nucleotide-disulphide oxidoreductase, class-II, active site + Renal dipeptidase family + Uncharacterised protein family Ycf49 + Calreticulin/calnexin + Actinin-type actin-binding domain, conserved site + Beta-hexosaminidase, eukaryotic type, N-terminal + Protein translocase subunit SecA + Peptidase M1, alanyl aminopeptidase, Ig-like fold + Oleate hydratase + Cytochrome ubiquinol oxidase subunit 1 + Orotidine 5'-phosphate decarboxylase, active site + Ribonucleotide reductase small subunit family + HORMA domain + Prefoldin alpha-like + Electron transfer flavoprotein, alpha subunit, C-terminal + Peptidase M24A, methionine aminopeptidase, subfamily 1 + Helicase-associated + Uncharacterised domain UPF0126 + MoeA, C-terminal, domain IV + Cytochrome c oxidase assembly protein CtaG/Cox11, domain + Somatomedin B domain + Pyrroline-5-carboxylate reductase, dimerisation domain + Transcriptional regulator TACO1-like + MOSC, N-terminal beta barrel + Uncharacterised protein family UPF0753 + Ribosomal protein L27 + Uncharacterised domain YOR215C, mitochondrial + KDPG/KHG aldolase + Flavodoxin-like fold + CidB/LrgB family + SAICAR synthetase, conserved site + VDE lipocalin domain + Phosphoglucose isomerase, conserved site + RQC domain + MnmE, helical domain + Phosphoenolpyruvate carboxykinase, N-terminal + Lactate/malate dehydrogenase, N-terminal + APOBEC-like, N-terminal + Arginine biosynthesis protein ArgJ + Tetrahydrofolate dehydrogenase/cyclohydrolase + Glucosidase II beta subunit, N-terminal + Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain + TerD domain + Threonine-tRNA ligase, class IIa + Small protein B + Roadblock/LAMTOR2 domain + Phosphatidylethanolamine-binding protein + UDP-glucose/GDP-mannose dehydrogenase, C-terminal + tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG + XPG conserved site + Fe-S metabolism associated domain, SufE-like + Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site + Glutamate synthase, central-N + TRAP transporter solute receptor, TAXI family + Bacteriophage phiJL001, Gp84, C-terminal + O-acyltransferase WSD1, C-terminal + DNA polymerase beta, thumb domain + Histone acetyltransferase Rtt109/CBP + Serine hydroxymethyltransferase, pyridoxal phosphate binding site + FeS cluster insertion, C-terminal, conserved site + NusG, N-terminal + Glycosyl transferase family 39/83 + 5-formyltetrahydrofolate cyclo-ligase + Penicillin/GL-7-ACA/AHL/aculeacin-A acylase + UbiE/COQ5 methyltransferase + Folylpolyglutamate synthetase + Ribosomal protein S18 + Translation elongation factor Ts, conserved site + Rpn11/EIF3F, C-terminal + CTLH/CRA C-terminal to LisH motif domain + LacI-type HTH domain + Dihydrodipicolinate reductase, N-terminal + MutL, C-terminal, dimerisation + Sterol-sensing domain + N-formylglutamate amidohydrolase + Vesicle transport v-SNARE, N-terminal + Dihydroorotase, conserved site + Pyruvate phosphate dikinase, PEP/pyruvate-binding + NmrA-like domain + Protein of unknown function with TPD sequence-motif + Arginine-tRNA ligase + Vitamin B12-dependent methionine synthase, activation domain + Ribosomal protein L19 + ATP synthase, F0 complex, subunit C + Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ + Integrase, N-terminal zinc-binding domain-like + Ribosomal protein S16 domain + Domain of unknown function DUF4457 + Pseudouridine synthase II, N-terminal + Protein of unknown function DUF2009 + 1,3-beta-glucan synthase subunit FKS1-like, domain-1 + DNAJ-containing protein, X-domain + DDH domain + AAA+ ATPase domain + Phenazine biosynthesis PhzF protein + ATPase, OSCP/delta subunit + Glycosyl transferase, family 4 + Transketolase binding site + Octanoyltransferase, conserved site + Ribosomal protein L6, conserved site + 50S ribosomal protein uL4 + Ferric reductase transmembrane component-like domain + Piwi domain + tRNA dimethylallyltransferase + Uncharacterised protein family UPF0047 + Zinc finger, UBP-type + Scaffold protein Nfu/NifU, N-terminal + 1, 4-beta cellobiohydrolase + Bacteriophage lambda, GpH, tail tape measure, C-terminal + Fructose-bisphosphate aldolase, class-II + Putative phage-type endonuclease + Elongation factor 4 + Galactosyltransferase, C-terminal + Uracil-DNA glycosylase family 1 + Bacterial bifunctional deaminase-reductase, C-terminal + Carbohydrate binding module family 20 + Citrate synthase-like, small alpha subdomain + Citrate synthase-like, large alpha subdomain + Domain of unknown function DUF3883 + Ferritin/DPS protein domain + Ribosomal protein S12, bacterial-type + tRNA-specific 2-thiouridylase + TadE-like + Topoisomerase C-terminal repeat + 3-dehydroquinate synthase domain + Bulb-type lectin domain + O-methyltransferase, family 3 + Sec23/Sec24, helical domain + ABC transporter Uup, C-terminal + Universal stress protein A + Ribosomal protein L18 + DNA polymerase, helix-hairpin-helix motif + FdhE-like + Moybdenum cofactor oxidoreductase, dimerisation + GLE1-like + IMP dehydrogenase / GMP reductase, conserved site + S-adenosyl-L-homocysteine hydrolase, conserved site + YABBY protein + GTPase Der, C-terminal KH-domain-like + Phosphoribosylglycinamide synthetase, conserved site + Amidase, conserved site + Histidinol dehydrogenase + ABA DEFICIENT 4-like + ATP-dependent helicase, C-terminal + Flavin monooxygenase-like + ABC transporter periplasmic binding domain + TGS-like domain + Prenylated rab acceptor PRA1 + Ribose-phosphate diphosphokinase + F1F0 ATP synthase OSCP/delta subunit, N-terminal domain + Translation elongation factor EFG/EF2 + Translation elongation factor EFTu/EF1A, bacterial/organelle + Major sperm protein (MSP) domain + V-ATPase proteolipid subunit + ATP synthase, alpha subunit, C-terminal + Protein of unknown function DUF1350 + Nuclear control of ATP synthase 2 + Peptidase M41, FtsH extracellular + 3-hydroxyisobutyrate dehydrogenase + Scramblase + Peptidase M50 + NADH-quinone oxidoreductase, subunit D + Glycoside hydrolase family 30 + Peptidyl-tRNA hydrolase, conserved site + Ribosome biogenesis protein BMS1/TSR1, C-terminal + Succinylglutamate desuccinylase/aspartoacylase + 5'-3' exonuclease, alpha-helical arch, N-terminal + 5'-3' exonuclease, C-terminal domain + LOG family + Guanylate kinase, conserved site + MnmG-related, conserved site + Ribosomal RNA adenine methylase transferase, conserved site + Cytochrome b/b6, C-terminal + Cytochrome b/b6, N-terminal + YrdC-like domain + THUMP domain + S-formylglutathione hydrolase + Protein kinase, C-terminal + Ribosomal protein L11, bacterial-type + Restriction endonuclease, type I, HsdS + Zinc finger, AN1-type + Phosphotyrosine protein phosphatase I superfamily + RNA polymerase, alpha subunit, C-terminal + ATP-dependent protease, HslV subunit + Superoxide dismutase, copper/zinc, binding site + Cyclin, C-terminal domain + LMBR1-like membrane protein + Methyltransferase TRM13 + Ribosomal protein L7/L12 + Zinc finger, RING-H2-type + NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal + Ribosomal protein L9, C-terminal + Longin domain + Carbamoyl-phosphate synthase, small subunit + Ribonuclease II/R, conserved site + Aminotransferase, class IV, conserved site + Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal + Methylmalonyl-CoA mutase, alpha chain, catalytic + SsrA-binding protein + Beta-propeller repeat + DNA-directed DNA polymerase, family B, exonuclease domain + Tetratricopeptide TPR-4 + Ribosomal protein S2, conserved site + RNA polymerase subunit, RPB6/omega + Domain of unknown function DUF861, cupin-3 + 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal + Tetrapyrrole biosynthesis, uroporphyrinogen III synthase + Disulphide bond formation protein DsbB/BdbC + Dihydrolipoamide dehydrogenase + Aspartate carbamoyltransferase + Dihydroprymidine dehydrogenase domain II + Peptidase M24, C-terminal domain + Sodium/potassium/calcium exchanger + Zinc ribbon, NADH pyrophosphatase + Poly-beta-hydroxybutyrate polymerase, N-terminal domain + Domain of unknown function DUF4217 + MutY, C-terminal + Glycosyl hydrolase family 30, beta sandwich domain + Ornithine decarboxylase + Bacteriophage/Gene transfer agent portal protein + Glycosyl hydrolases family 1, N-terminal conserved site + DNA topoisomerase, type IA, zn finger + Ribosomal RNA adenine methyltransferase KsgA/Erm + Delta-aminolevulinic acid dehydratase + Ribosomal protein L17 + Glycoside hydrolase family 38, N-terminal domain + Glutathione synthase, alpha-helical, eukaryotic + Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase + Ubiquitin conjugation factor E4, core + Rieske iron-sulphur protein, C-terminal + Orn/DAP/Arg decarboxylase 2, conserved site + Ribosomal protein L28 + Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal + Xaa-Pro dipeptidyl-peptidase-like domain + Zinc finger, FPG/IleRS-type + Protein of unknown function DUF2237 + 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase + 5'-Nucleotidase/apyrase + SecA preprotein, cross-linking domain + TRAM domain + Transcriptional regulator TACO1-like, domain 3 + Ribosomal protein L28/L24 + Deoxyxylulose-5-phosphate synthase + Cleavage/polyadenylation specificity factor, A subunit, C-terminal + Shikimate dehydrogenase substrate binding, N-terminal + 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain + Bacteriophage VT1-Sakai, H0018 + Phosphoribosyl-ATP pyrophosphohydrolase-like + Zinc finger, TAZ-type + Ribosomal protein L1, conserved site + Guanine nucleotide binding protein (G-protein), alpha subunit + ABC transporter permease MalE + Beta galactosidase small chain/ domain 5 + Septin-type guanine nucleotide-binding (G) domain + Protein of unknown function DUF465 + SecA Wing/Scaffold + Ribosomal protein L27, conserved site + HELP + Trigger factor, ribosome-binding, bacterial + DNA topoisomerase, type IA, active site + Nucleotide sugar epimerase + Peptidase S16, active site + SAICAR synthetase/ADE2, N-terminal + Glycosyl transferase, family 17 + Sec-independent protein translocase protein TatA/B/E + Poly A polymerase, head domain + Serine-tRNA ligase, type1 + Galactose-1-phosphate uridyl transferase, N-terminal + GPI mannosyltransferase + Ribosomal protein L3, conserved site + NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H + Peptidase M28 + Ribosome maturation factor RimP, C-terminal + Hedgehog/Intein (Hint) domain + WLM domain + Tim44-like domain + S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA + Carbamoyl-phosphate synthase small subunit, N-terminal domain + Riboflavin kinase domain + Ferrodoxin-fold anticodon-binding domain + Domain of unknown function DUF4203 + ATP synthase, F1 complex, gamma subunit conserved site + Protein-export membrane protein SecD/SecF, archaeal and bacterial + Protein of unknown function DUF268, Caenorhabditis species + Nucleoid-associated protein YbaB/EbfC family + Penicillin-binding protein, dimerisation domain + Copper type II, ascorbate-dependent monooxygenase, N-terminal + Amino acid/polyamine transporter 2 + TM2 domain + B9 domain + Dual-specificity RNA methyltransferase RlmN + Ribosomal protein S5, N-terminal, conserved site + Transcription factor 25 + Arginyl tRNA synthetase N-terminal domain + Zinc finger, TFIIS-type + Molybdopterin cofactor biosynthesis C (MoaC) domain + Protein of unknown function DUF112, transmembrane + Protein of unknown function DUF924 + Ribosomal protein S7, conserved site + Harbinger transposase-derived nuclease domain + Adenine nucleotide alpha hydrolase-like domains + mRNA (guanine-N(7))-methyltransferase domain + Ceramidase + Vacuolar protein sorting-associated protein 35 + Tricarboxylate/iron carrier + NAD(P) transhydrogenase, alpha subunit, C-terminal + Ribosomal protein S16 + Diaminopimelate epimerase, DapF + Protein of unknown function DUF411 + PLAC8 motif-containing protein + Glucokinase + Phosphotransferase KptA/Tpt1 + N-(5'phosphoribosyl) anthranilate isomerase (PRAI) + Condensation domain + Argininosuccinate lyase, C-terminal + Ribosomal protein L16 + ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type + Dynamin GTPase effector + Molybdopterin dinucleotide-binding domain + NAD-dependent DNA ligase, adenylation + PH-BEACH domain + Ribosomal protein L14P, conserved site + Gamma interferon inducible lysosomal thiol reductase GILT + Putative zinc- or iron-chelating domain containing protein + Uncharacterised domain NUC173 + Phosphoglucose isomerase (PGI) + Probable peptidoglycan glycosyltransferase FtsW/RodA + Glycosyl transferase family 3, N-terminal domain + Diaminopimelate decarboxylase, LysA + Phytochelatin synthase + Cilia/flagella-associated protein 20/WDR90/C3orf67 + Ubiquinone biosynthesis protein Coq4 + DNA mismatch repair protein MutS, clamp + GroES chaperonin family + Trigger factor, C-terminal + Transmembrane protein 65 + Sigma-54 interaction domain, ATP-binding site 2 + Thymidine kinase + NADH:ubiquinone oxidoreductase, subunit 1, conserved site + Carboxylase, conserved domain + Ribosome-binding ATPase YchF/Obg-like ATPase 1 + DNA/pantothenate metabolism flavoprotein, C-terminal + Phage portal protein, HK97 + Galactokinase + 30s ribosomal protein S13, C-terminal + Vacuolar protein sorting-associated protein 54, N-terminal + Flavoprotein + Protein of unknown function DUF3119 + Protein patched/dispatched + Terminase large subunit, Lambdalikevirus-type + Kringle, conserved site + Beta-adaptin appendage, C-terminal subdomain + NTP pyrophosphohydrolase MazG, putative catalytic core + Polyribonucleotide nucleotidyltransferase, RNA-binding domain + Peptidase C13, legumain + Anoctamin, dimerisation domain + Smooth muscle protein/calponin + Fructose-2,6-bisphosphatase + Cytochrome c oxidase assembly protein CtaG/Cox11 + Initiation factor eIF-4 gamma, MA3 + PAP/25A-associated + Permease LptG/LptF-related + GidA associated domain 3 + Translation initiation factor aIF-2, bacterial-like + Acetate-CoA ligase + Ribosomal protein S4, conserved site + Carbohydrate-binding domain, family 9 + Molybdenum cofactor synthesis C-terminal + UvrC family homology region + Riboflavin kinase domain, bacterial/eukaryotic + Lipocalin/cytosolic fatty-acid binding domain + DNA topoisomerase, type IIA, subunit B + Glycoside hydrolase, family 28 + Glycoside hydrolase 38/57, N-terminal domain + Phosphoribosylglycinamide synthetase, N-terminal + Proline racemase family + ATP-grasp fold, succinyl-CoA synthetase-type + Ribosomal protein S3, C-terminal + Catalase core domain + Ribosomal protein L3, bacterial/organelle-type + Shikimate kinase/gluconokinase + Acyl-CoA dehydrogenase, N-terminal, bacteria + NET domain + Glutamate synthase, alpha subunit, C-terminal + PWI domain + Ferric-uptake regulator + SAC3/GANP/THP3 + 26S proteasome regulatory subunit P45-like + 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal + PHB de-polymerase, C-terminal + Wilm's tumour protein + Anthranilate synthase/para-aminobenzoate synthase like domain + Cupin 1 + Flagellar motor switch protein FliG, alpha-helical + ATP synthase, F1 complex, delta/epsilon subunit, N-terminal + Alcohol dehydrogenase class III + YCII-related + tRNA threonylcarbamoyl adenosine modification protein TsaE + Molybdopterin biosynthesis MoaE + Alpha-glycerophosphate oxidase, C-terminal + Transglycosylase SLT domain 2 + Ribosomal protein S19 conserved site + Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding + Galactokinase, conserved site + Glutathione S-transferases, class Zeta + Thiamin pyrophosphokinase, vitamin B1-binding domain + Ribosomal protein L21 + UvrB, YAD/RRR-motif-containing domain + Ribosomal protein L20 C-terminal domain + SAF domain + Ribosomal RNA adenine dimethylase + Nitrite/sulphite reductase 4Fe-4S domain + Ribose 5-phosphate isomerase, type A + P-type ATPase, C-terminal + Translation initiation factor 3, N-terminal + 3-oxoacid CoA-transferase, subunit B + Ribosomal protein L34 + Thiazole synthase ThiG + Tryptophan-tRNA ligase + Leucine-tRNA ligase + Ribose-phosphate pyrophosphokinase, N-terminal domain + Glycine cleavage system P protein + TonB, C-terminal + Gamma-glutamylcyclotransferase, AIG2-like + Peroxisomal biogenesis factor 11 + Integrase, SAM-like, N-terminal + Prephenate dehydratase + Phosphofructokinase domain + Alpha-L-rhamnosidase, six-hairpin glycosidase domain + DNA-binding protein Dps + Calreticulin/calnexin, conserved site + Transcription regulator Rrf2-type, conserved site + Rho GDP-dissociation inhibitor domain + Domain of unknown function DUF4200 + RNA methyltransferase RlmH + Queuosine precursor transporter + D-galactoside/L-rhamnose binding SUEL lectin domain + Ketoacyl-synthetase, C-terminal extension + Polyhydroxyalkanoate depolymerase + Plasmid maintenance toxin/Cell growth inhibitor + Queuosine biosynthesis protein QueC + CH-like domain in sperm protein + C-terminal of Roc (COR) domain + Inositol monophosphatase, SuhB + Type III secretion system inner membrane P protein + Phosphoribosyl-ATP pyrophosphohydrolase + Barrier- to-autointegration factor, BAF + Histidine biosynthesis, HisF + S-adenosylmethionine synthetase, central domain + S-adenosylmethionine synthetase, N-terminal + Anthranilate synthase component I-like + Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y + Arginine-tRNA-protein transferase, C-terminal + NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site + Zf-FLZ domain + Transient receptor potential channel, canonical + Heavy metal-associated domain, copper ion-binding + Protein of unknown function DUF778 + Glycoside hydrolase, family 2, active site + rRNA small subunit methyltransferase G + tRNA-guanine transglycosylase + DNA polymerase III, alpha subunit + HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase + Ras GTPase-activating protein + Porphobilinogen deaminase, dipyrromethane cofactor binding site + 3-keto-5-aminohexanoate cleavage enzyme + Intradiol ring-cleavage dioxygenase, core + Malic enzyme, conserved site + Molybdenum cofactor biosynthesis protein A + Fagellar hook-basal body protein, FlgE/F/G + Protein of unknown function DUF885 + Adenylyl-sulfate kinase + Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal + DNA mismatch repair protein family + Domain of unknown function DUF4476 + Ribosomal protein L22, bacterial/chloroplast-type + Na+/H+ antiporter NhaA + Translation Initiation factor eIF- 4e + Protein-export membrane protein SecD/SecF/SecDF, conserved site + DNA polymerase family X + Asp/Glu/hydantoin racemase + Glycine-tRNA ligase, beta subunit + WASH complex, subunit strumpellin + Thymidylate synthase + Small multidrug resistance protein family + Alkaline phosphatase + SAM-dependent methyltransferase TRM5/TYW2-type + Copper chaperone PCuAC + Cytochrome c-type biogenesis protein CcmC + Glycoside hydrolase, family 2 + Cell division protein ZapA-like + Zinc finger/thioredoxin putative + Adenylyl cyclase class-4/guanylyl cyclase, conserved site + Cytochrome c oxidase subunit II-like C-terminal + VPLPA-CTERM protein sorting domain + Exportin/Importin, Cse1-like + COQ9 + 3-dehydroquinate synthase AroB + ABC transporter, TroCD-like + Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like + Ribosomal protein L35, non-mitochondrial + Bacterial protein export chaperone SecB + Ketopantoate hydroxymethyltransferase + NADAR + AAA C-terminal domain + Ribosomal protein S4, bacterial-type + Restriction endonuclease, type I, HsdR + IstB-like ATP-binding protein + PLAT/LH2 domain + Flagellin, D0/D1 domain + Dihydrodipicolinate reductase, C-terminal + Type III pantothenate kinase + Phosphatidate cytidylyltransferase + Cytidylyltransferase IspD/TarI + Zinc-finger binding domain of transposase IS66 + D-alanine--D-alanine ligase, N-terminal domain + Ribosomal protein S14, conserved site + Ku70/Ku80 beta-barrel domain + ERCC4 domain + Diacylglycerol glucosyltransferase, N-terminal + Type II/III secretion system + 14-3-3 domain + Zinc knuckle CX2CX3GHX4C + Protein of unknown function DUF3387 + tRNA N6-adenosine threonylcarbamoyltransferase, TsaD + FMN-dependent alpha-hydroxy acid dehydrogenase, active site + Protein of unknown function DUF2505 + NAD-glutamate dehydrogenase + Pantoate-beta-alanine ligase + IrrE N-terminal-like domain + Protein of unknown function DUF1013 + Anthranilate synthase component I, N-terminal + UbiE/COQ5 methyltransferase, conserved site + RimM protein + Ribosomal protein L32p + Amidophosphoribosyltransferase + Galactose-1-phosphate uridyl transferase, C-terminal + Uracil-DNA glycosylase, active site + Glycoside hydrolase, family 5, conserved site + Sterol reductase, conserved site + Prokaryotic N-terminal methylation site + DNA topoisomerase I, catalytic core, eukaryotic-type + La protein, RNA-binding domain + Cell wall hydrolase, SleB + Guanine nucleotide exchange factor, N-terminal + GDP-mannose 4,6-dehydratase + Protohaem IX farnesyltransferase + Uroporphyrinogen decarboxylase HemE + Orotidine 5'-phosphate decarboxylase + Biosynthetic peptidoglycan transglycosylase + MoeA, N-terminal and linker domain + Store-operated calcium entry regulator STIMATE/YPL162C + PROCN domain + Chromosomal replication initiator protein DnaA + Acetyl-CoA carboxylase carboxyl transferase, beta subunit + tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY + Replication factor C, C-terminal + Bile acid:sodium symporter/arsenical resistance protein Acr3 + Tyrosine-tRNA ligase + Importin-alpha, importin-beta-binding domain + 3-isopropylmalate dehydratase, small subunit + Glycoside hydrolase, family 45 + DXP reductoisomerase C-terminal domain + Hydroxymethylglutaryl-coenzyme A synthase, N-terminal + Glycoside hydrolase, family 42, N-terminal + dTDP-4-dehydrorhamnose 3,5-epimerase-related + P2X purinoreceptor + Galactose-1-phosphate uridyl transferase, class I + Glutathione-specific gamma-glutamylcyclotransferase + Calcium-dependent channel, 7TM region, putative phosphate + GTP-binding protein Era + Cobalamin biosynthesis protein CobT VWA domain + Cobalamin (vitamin B12)-binding module, cap domain + PepSY domain + tRNA-splicing ligase, RtcB + KH domain, NusA-like + Pheromone shutdown, TraB + Thymidine kinase, conserved site + Magnesium transporter, MgtE intracellular domain + Translation initiation factor IF-2, N-terminal + Arsenate reductase-like + FAM91, N-terminal domain + Cytochrome c1 + PEP-utilising enzyme, conserved site + Diaminopimelate epimerase, active site + Uncharacterised protein family CoxE-like + Peptidase S8, subtilisin, His-active site + FANCL C-terminal domain + Peroxidases heam-ligand binding site + Ubiquinone biosynthesis protein COQ9 + Cysteinyl-tRNA synthetase/mycothiol ligase + Radial spokehead-like protein + Fatty acid synthesis PlsX protein + Pseudouridine synthase I, TruA + Carbohydrate-binding WSC + Spermidine synthase, tetramerisation domain + Formate dehydrogenase accessory protein + Zinc finger, DNL-type + Cell shape determining protein MreB + Protein SCAI + Protein of unknown function DUF4170 + GTP cyclohydrolase N-terminal + ATP-dependent RNA helicase HrpB, C-terminal + Dehydroquinase, class II + Thiamine phosphate synthase + Ribosomal protein L36 + Peptidyl-tRNA hydrolase, PTH2 + THO complex, subunitTHOC2, C-terminal + SprT-like + GcrA cell cycle regulator + Glycosyl hydrolase family 38, C-terminal + S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain + Na/H antiporter domain + 3'5'-cyclic nucleotide phosphodiesterase, conserved site + Vacuolar protein sorting-associate protein Vta1/Callose synthase, N-terminal domain + Argininosuccinate lyase + CCAAT-binding factor + WHIM1 domain + Ornithine/putrescine carbamoyltransferase + rRNA-processing arch domain + SH3-like domain, bacterial-type + Indole-3-glycerol phosphate synthase, conserved site + ATP synthase, F1 complex, delta/epsilon subunit + Annexin + ATP-citrate lyase/succinyl-CoA ligase, active site + Surfeit locus 1/Shy1 + Undecaprenyl-diphosphatase UppP + 1-deoxy-D-xylulose 5-phosphate reductoisomerase + Ribosomal protein L7Ae/L8/Nhp2 family + Twin-arginine translocation pathway, signal sequence, bacterial/archaeal + CRC domain + GMP synthase, glutamine amidotransferase + PRP8 domain IV core + Aromatic amino acid hydroxylase + D-serine dehydratase-like domain + Ribosomal protein L29/L36 + Domain of unknown function DUF2828 + Chorismate synthase + N-acetyl-gamma-glutamyl-phosphate reductase, type 2 + Imidazole glycerol phosphate synthase, subunit H + Mre11, DNA-binding + Endonuclease V + Na+/H+ antiporter, NhaC-like, C-terminal + Quinone oxidoreductase/zeta-crystallin, conserved site + DNA recombination-mediator protein A + Chaperone DnaK + Chaperone DnaJ + RUN domain + PHP domain + Glycoside hydrolase, family 37 + Ribosomal protein L15, conserved site + Metalloprotease TldD/PmbA, N-terminal domain + Ribosomal protein L16, conserved site + Selenoprotein, Rdx type + GMP phosphodiesterase, delta subunit + CDC48, N-terminal subdomain + Protein of unknown function DUF229 + 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal + Isoprenylcysteine carboxyl methyltransferase + Sphingolipid delta4-desaturase, N-terminal + NAD(P)H-quinone oxidoreductase subunit D/H + Glutamine synthetase, N-terminal conserved site + MmgE/PrpD + Protein DA1-like + Ribosomal protein L18, bacterial-type + Domain of unknown function DUF2263 + Biotin synthase/Biotin biosynthesis bifunctional protein BioAB + 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK + Pyrimidine 5'-nucleotidase, eukaryotic + GTP-binding protein TypA + Replication termination factor 2, RING-finger + Peptidase S46 + Peptide chain release factor 3, C-terminal + PTR2 family proton/oligopeptide symporter, conserved site + Dynein regulatory complex protein 1, C-terminal + YcnI-like + Protein of unknown function DUF2141 + Peptidoglycan biosynthesis protein MurJ + Adenine deaminase C-terminal domain + Casein kinase II, regulatory subunit, alpha-helical + NADH dehydrogenase, subunit C + TNFR/NGFR cysteine-rich region + Aspartate kinase, conserved site + Orthogonal Bundle domain in ATP12 + Methyladenine glycosylase + Serine incorporator/TMS membrane protein + Arp2/3 complex subunit 2/4 + Potassium channel, inwardly rectifying, Kir + NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site + HemN, C-terminal + Biotin and thiamin synthesis-associated domain + Ubiquinone biosynthesis O-methyltransferase + SUF system FeS cluster assembly, SufB + FeS cluster assembly SUF system, ATPase SufC + Exonuclease VII, large subunit, C-terminal + Cytochrome c-type biogenesis protein CcmF, C-terminal + NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 + Syntaxin, N-terminal domain + Protein FAM221A/B + Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain + 4-hydroxy-tetrahydrodipicolinate synthase, DapA + Uncharacterised protein family UPF0093 + Putative sodium bile acid cotransporter + Transcription elongation factor, GreA/GreB, N-terminal + Phosphorylated adapter RNA export protein, RNA-binding domain + Ureidoglycolate lyase domain + Prohibitin + Nicotinate phosphoribosyltransferase family + Transport protein particle (TRAPP) component + Glycosyl hydrolase family 63, C-terminal + UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal + 2-oxoglutarate dehydrogenase E1 component + KDPG/KHG aldolase, active site 2 + 3-oxoacyl-[acyl-carrier-protein] synthase 2 + HTH domain AraC-type, conserved site + Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain + Tex-like protein, HTH domain + Uncharacterised domain CHP00451 + Glutamate-tRNA ligase, bacterial/mitochondrial + Phenylalanyl-tRNA synthetase, class IIc, alpha subunit + SPOC-like, C-terminal domain + Transposase, IS111A/IS1328/IS1533, N-terminal + UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal + Acyl-CoA desaturase + Domain of unknown function DUF547 + P-type trefoil domain + DeoC/FbaB/ lacD aldolase + Transcription termination factor NusA, C-terminal duplication + Root UVB sensitive family + Glutaminyl-peptide cyclotransferase + DNA polymerase family X, beta-like + 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site + Cysteine oxygenase/2-aminoethanethiol dioxygenase + Conserved hypothetical protein CHP02302, transmembrane + Protein of unknown function DUF760 + Putative S-adenosyl-L-methionine-dependent methyltransferase + NAD-dependent DNA ligase, OB-fold + 4-hydroxy-3-methylbut-2-enyl diphosphate reductase + Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase A + Phosphoribosyl-AMP cyclohydrolase domain + V-type ATPase, V0 complex, 116kDa subunit family + Phosphoserine phosphatase, domain 2 + 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site + Phosphate transport system protein PhoU + Proline iminopeptidase + Lumazine-binding domain + Putative membrane protein insertion efficiency factor + Triacylglycerol lipase + DHHA2 domain + Solute-binding family 1 + NADH-quinone oxidoreductase subunit E-like + Sugar fermentation stimulation protein + Armet protein + Heat shock protein DnaJ, cysteine-rich domain + Lipin/Ned1/Smp2 (LNS2) + Inner membrane protein YebE + Bystin + Cobalt chelatase, CobT subunit + P-type ATPase, subfamily IIIA + TPM domain + Ribosomal protein L5, conserved site + Bacteriophage SPP1, head-tail adaptor + Ferrochelatase, active site + Galactose-1-phosphate uridyl transferase, class I His-active site + RST domain of plant C-terminal + Heat shock protein Hsp90, conserved site + Histone H4, conserved site + Type II pantothenate kinase + Proteinase inhibitor I78 + 60S ribosomal protein L6E + tRNA pseudouridylate synthase B, C-terminal + Ribosomal protein L9, bacteria/chloroplast + DAHP synthetase I/KDSA + 2-oxoglutarate dehydrogenase E1 component, N-terminal domain + ATP synthase, F0 complex, subunit A, active site + Integral membrane protein TerC, riboswitch-linked + Valyl-tRNA synthetase, tRNA-binding arm + Protein-lysine N-methyltransferase Efm5 + Ribonucleotide reductase, class I , alpha subunit + Acetyl-coenzyme A transporter 1 + Actin/actin-like conserved site + GxGYxYP putative glycoside hydrolase, N-terminal + Phosphotyrosyl phosphatase activator, PTPA + Aspartate-semialdehyde dehydrogenase, beta-type + Domain of unknown function DUF304 + Sialate O-acetylesterase domain + Domain of unknown function DUF306, Meta/HslJ + 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type + MgsA AAA+ ATPase C-terminal + Argininosuccinate synthase + Protein of unknown function DUF1517 + Plant ascorbate peroxidase + Carbamoyl-phosphate synthase, large subunit + Hydroxymethylglutaryl-CoA reductase, class I/II + Sarcosine oxidase subunit beta + Sarcosine oxidase, delta subunit, heterotetrameric + Glutamate/phenylalanine/leucine/valine dehydrogenase + Senescence marker protein-30 (SMP-30) + Glycosyl transferase, family 13 + Transposase InsH, N-terminal + Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain + Polyphosphate kinase N-terminal domain + Succinate dehydogenase/fumarate reductase N-terminal + Domain of unknown function DUF5127 + Myo-inositol-1-phosphate synthase, GAPDH-like + Sec39 domain + RNA polymerase sigma factor 70, region 4 type 2 + PurE domain + Cytochrome c-type biogenesis protein CcmF + Cytochrome c-type biogenesis protein + Hypoxia induced protein, domain + NADH-ubiquinone oxidoreductase, 20 Kd subunit + NADH:ubiquinone oxidoreductase-like, 20kDa subunit + Conserved hypothetical protein CHP02058 + Plus-3 domain + Peptidase T1A, proteasome beta-subunit + Peptidase T2, asparaginase 2 + Translation initiation factor 3 + ATP-citrate lyase/succinyl-CoA ligase, conserved site + Transcriptional coactivator/pterin dehydratase + GTP-binding protein TrmE, N-terminal + Transmembrane secretion effector + Pyridoxal phosphate homeostasis protein + Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex + Isocitrate lyase + Dihydrolipoamide succinyltransferase + Cytochrome c, class IC + Cation transporter + DNA polymerase type-Y, HhH motif + Atypical Arm repeat + Succinate dehydrogenase/fumarate reductase iron-sulphur protein + NADH pyrophosphatase-like, N-terminal + Fumarylacetoacetase, N-terminal + Transposase-like, Mu, C-terminal + Ribosomal protein L24/L26, conserved site + Acetylglutamate kinase + Thymidylate kinase, conserved site + S-adenosylmethionine synthetase, C-terminal + S-adenosylmethionine synthetase, conserved site + Ribosomal protein S13, bacterial-type + Ribosomal protein S11, bacterial-type + Peptidase M18 + Ubiquitin/SUMO-activating enzyme E1 + Transcriptional regulator PAI 2-type + RNA polymerase, subunit omega/K/RPB6 + FUN14 + Mandelate racemase/muconate lactonizing enzyme, conserved site + Caudovirus, tape measure, N-terminal + Methyl-CpG DNA binding + XdhC- CoxI + Tim10/FAM136A-like domain + CENP-T/Histone H4, histone fold + Terminase, large subunit gp17-like + DNA ligase, ATP-dependent + Fumarate reductase/succinate dehydrogenase, FAD-binding site + Ribosomal protein S19, bacterial-type + UDP-3-O-acyl N-acetylglucosamine deacetylase + CTP synthase + Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 + Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site + Tetratricopeptide repeat-like domain + MoaA/nifB/pqqE, iron-sulphur binding, conserved site + Virulence factor BrkB + Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ + 3-oxoacyl-(acyl-carrier-protein) reductase + Cytochrome C oxidase subunit II, transmembrane domain + Type III secretion system FHIPEP + Transposase, IS66 + Peptidase S49, N-terminal proteobacteria + Carbohydrate kinase, predicted, conserved site + ATP:cob(I)alamin adenosyltransferase, PduO-type + Phospholipase C, phosphatidylinositol-specific, Y domain + PhoH-like protein + Polysaccharide export protein + OsmC/Ohr family + Ribosomal protein L35 + Intradiol ring-cleavage dioxygenase, C-terminal + Protein of unknown function DUF938 + Exopolysaccharide biosynthesis protein YbjH + Glutathione peroxidase active site + Histone H2A, C-terminal domain + Phosphoglucose isomerase, C-terminal + Metalloprotease catalytic domain, predicted + Ribosomal protein S7, bacterial/organellar-type + Ribosomal protein S5, bacterial-type + Concentrative nucleoside transporter N-terminal domain + Histidinol-phosphate aminotransferase family + NADH-quinone oxidoreductase, chain I + YjeF N-terminal domain + Thymidylate kinase + Phosphoglycerate kinase, conserved site + RarD protein + Ammonium transporter + Protein translocase complex, SecE/Sec61-gamma subunit + GTPase HflX + Transglycosylase-associated protein + 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal + Potassium channel, inwardly rectifying, Kir, cytoplasmic + Translation elongation factor, IF5A C-terminal + Rho termination factor, RNA-binding domain + Rho termination factor, N-terminal + Ribosomal protein L33, conserved site + Ribosomal protein L35, conserved site + Ribosomal protein S10, conserved site + Ribosomal protein S13, conserved site + Josephin domain + Dihydroneopterin aldolase/epimerase domain + Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase + Domain of unknown function DUF1279 + GspD/PilQ family + Domain of unknown function DUF155 + Allosteric substrate binding domain + Guanylate-binding protein, C-terminal + Small-subunit processome, Utp12 + DNA polymerase beta, palm domain + Reductase, C-terminal + Protein-tyrosine phosphatase SIW14-like, eukaryotic + ELMO domain + Twin-arginine translocation protein TatB-like + RTX secretion protein D, Gram-negative bacteria + Glycyl-tRNA synthetase + Domain of unknown function DUF4033 + Prephenate dehydratase, conserved site + Flavin transferase ApbE + Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A + Thiamin pyrophosphokinase, catalytic domain + Putative fluoride ion transporter CrcB + Transcription elongation factor, GreA/GreB, C-terminal + Ubiquinol-cytochrome c reductase, iron-sulphur subunit + Cobalamin-dependent methionine synthase + Palmitoyl protein thioesterase + Inositol phosphatase + Ribosomal protein L24 + Domain of unknown function DUF4205 + Leucyl-tRNA synthetase, editing domain + Transposase, mutator type + Polyphosphate kinase-2-related + RNA polymerase sigma factor 70, region 1.1 + Schiff base-forming aldolase, active site + Schiff base-forming aldolase, conserved site + C-terminal-processing peptidase S41A + Nitrogen regulatory protein P-II, urydylation site + Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain + Ribosomal protein L6, bacterial-type + Protein of unknown function DUF2254, membrane + CobN/magnesium chelatase + Oligosaccharyl transferase, STT3 subunit + Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site + Putative phage terminase, small subunit, P27 family + Phosphatidylserine decarboxylase-related + Argininosuccinate synthase, conserved site + RNA-binding domain, S1, IF1 type + Ureohydrolase, manganese-binding site + ATP phosphoribosyltransferase, conserved site + Putative GTP-binding controlling metal-binding domain + ATP-cone domain + Glycine cleavage system H-protein/Simiate + 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase + Ribulose bisphosphate carboxylase, large subunit, C-terminal + Copper type II ascorbate-dependent monooxygenase, C-terminal + Protein of unknown function DUF616 + EH domain-containing protein, N-terminal + GTP cyclohydrolase I domain + rRNA adenine dimethylase-like + HI0933 insert-like domain + P25-alpha + Nop domain + TRAP transporter permease protein + Pyrroline-5-carboxylate reductase + 14-3-3 protein + Peptidase M16C associated + Endonuclease III-like, iron-sulphur cluster loop motif + Hydroxyacylglutathione hydrolase + DEK, C-terminal + Glycosyl transferase, family 19 + GDP dissociation inhibitor + Translin-associated factor X-interacting protein 1, N-terminal + Peptidase M75, Imelysin + Cullin protein, neddylation domain + EVE domain + Protein of unknown function DUF1917 + Anthrax toxin, edema factor, central + Tim10-like + Tryptophan 2,3-dioxygenase + Prokaryotic glutathione synthetase, ATP-binding + Acetyl-CoA biotin carboxyl carrier + Phosphoribosylglycinamide synthetase + C-methyltransferase + Esterase, PHB depolymerase + PA domain + Tryptophan synthase, beta chain, conserved site + Tryptophan synthase, beta chain + Glycosyl transferase, family 11 + DNA-directed RNA polymerase, alpha subunit + FtsK gamma domain + DhaK domain + GPN-loop GTPase + GMP synthase, C-terminal + Methylmalonyl-CoA mutase, C-terminal + NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 + Sulphate adenylyltransferase catalytic domain + POTRA domain, BamA/TamA-like + Glycine cleavage system H-protein, subgroup + Nitrogen regulatory protein PII + Lumazine/riboflavin synthase + Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site + Protein of unknown function DUF3593 + Ribosomal protein L30, ferredoxin-like fold domain + ER lumen protein retaining receptor + Acyl-CoA dehydrogenase, C-terminal domain + Ctr copper transporter + cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain + ER membrane protein complex subunit 1, C-terminal + Endoplasmic reticulum resident protein 29, C-terminal + ATP12, ATP synthase F1-assembly protein + AP180 N-terminal homology (ANTH) domain + PepSY-associated TM protein + Formyl transferase, C-terminal + Protein Iojap/ribosomal silencing factor RsfS + Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase + Pyrophosphate-energised proton pump + Casein kinase II, regulatory subunit + RNA polymerase Rpb7, N-terminal + UvrD-like helicase C-terminal domain + Glycosyltransferase WbsX + Autophagy-related protein 27 + YHYH domain + Peptidase M17, leucyl aminopeptidase, N-terminal + tRNA-dihydrouridine synthase, putative, C-terminal + RNA 2-O ribose methyltransferase, substrate binding + Concentrative nucleoside transporter C-terminal domain + Cdc37, C-terminal + Peptide chain release factor 2 + PLAA family ubiquitin binding, PFU + Phosphoribosylaminoimidazole-succinocarboxamide synthase + RidA, conserved site + Octanoyltransferase + Ferredoxin [2Fe-2S], plant + Domain of unknown function DUF676, lipase-like + Acyl carrier protein (ACP) + Intracellular septation protein A + Protein of unknown function DUF45 + HNH endonuclease 5 + Parkin co-regulated protein + Dipeptide/tripeptide permease + Protein of unknown function DUF3141 + Heat shock protein Hsp33, N-terminal + DNA polymerase alpha/epsilon, subunit B + Peptidase M10 serralysin, C-terminal + Translation elongation factor P/YeiP, conserved site + Uroporphyrin-III C-methyltransferase + Phytase-like domain + Ribbon-helix-helix domain + PhoU domain + Uncharacterised conserved protein UCP032146 + Molybdenum cofactor biosynthesis, conserved site + D-alanine--D-alanine ligase/VANA/B/C, conserved site + Glycine-tRNA ligase, alpha subunit + YgfZ/GcvT conserved site + NADH-quinone oxidoreductase, chain M/4 + Yip1 domain + Voltage-dependent calcium channel, alpha-1 subunit + Neurotransmitter-gated ion-channel transmembrane domain + Imidazoleglycerol-phosphate dehydratase, conserved site + Peptidyl-tRNA hydrolase II domain + NADH-plastoquinone oxidoreductase, chain 5 subgroup + Cryptochrome/DNA photolyase class 1, conserved site, C-terminal + Cell division protein FtsZ + Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain + Argininosuccinate synthetase, catalytic/multimerisation domain body + CsbD-like domain + Neutral/alkaline non-lysosomal ceramidase, N-terminal + Myotubularin-like phosphatase domain + Imidazoleglycerol-phosphate dehydratase + Glutathione synthase, substrate-binding, eukaryotic + Coproporphyrinogen III oxidase, oxygen-independent related + Peptidase A22A, presenilin + Histidine-tRNA ligase + Cysteine-tRNA ligase + Acetohydroxy acid isomeroreductase C-terminal + Cysteine desulfurase, SufS + Uncharacterised protein family Ycf20 + Pseudouridine synthase, RluC/RluD + Protein of unknown function DUF1468 + Domain of unknown function DUF4965 + Glycosyl hydrolase, family 13, catalytic domain + Endoribonuclease YbeY, conserved site + Chorismate synthase, conserved site + Enkurin domain + Molybdenum cofactor biosynthesis C + SAC domain + DC1 + Lysine-specific demethylase-like domain + Methyltransferase putative zinc binding domain + PFTB repeat + Stress responsive alpha-beta barrel + RNA polymerase sigma factor 70, non-essential domain + SecY conserved site + GTP-binding protein, middle domain + SecA conserved site + CAP domain + Ribosomal protein L34, conserved site + Ribosomal protein L25 + Sarcosine oxidase, gamma subunit + CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase + Lumazine-binding protein + ABC transporter, FecCD-like + Chorismate mutase, bacteria + NADH ubiquinone oxidoreductase, F subunit + Glycoside hydrolase family 36 + Disulphide isomerase + ATP-dependent 6-phosphofructokinase + Endoribonuclease YbeY + Sec-independent periplasmic protein translocase TatC + Prepilin type IV endopeptidase, peptidase domain + Helix-turn-helix motif + Electron transfer flavoprotein, beta-subunit, conserved site + Coatomer, WD associated region + Outer membrane protein, OmpA-like, conserved site + Spindle pole body-associated protein Vik1/Cik1, microtubule binding domain + P-type ATPase, N-terminal + Tex protein, YqgF-like domain + ThiS, thiamine-biosynthesis + Molybdopterin converting factor, subunit 1 + Domain of unknown function DUF3506 + Solute-binding protein family 5, conserved site + Cytochrome c oxidase, subunit IV, bacterial aa3 type + Lysyl-tRNA synthetase, class II, C-terminal + Surfeit locus protein 2 + Homoserine dehydrogenase, conserved site + Carboxylesterase type B, conserved site + tRNA(Ile)-lysidine synthase, N-terminal + PB1 domain + YHS domain + Peptidase M12A + Phosphatidylinositol-specific phospholipase C, X domain + Ribosomal protein L25, beta domain + PRC-barrel domain + XdhC Rossmann domain + ATP-sulfurylase PUA-like domain + Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain + Fructose-1-6-bisphosphatase class I, N-terminal + Nitrate/nitrite sensing protein + Peptidase M15A, C-terminal + Lipoprotein SmpA/OmlA + SEP domain + Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal + PADR1 domain + Phosphoserine aminotransferase, Methanosarcina-type + Crossover junction endodeoxyribonuclease RuvC + AMP nucleosidase + Malate dehydrogenase, type 3 + Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent + Ribosomal protein L30, bacterial-type + Inosine-5'-monophosphate dehydrogenase + Heat shock protein Hsp33, helix hairpin bin domain + Glycine zipper 2TM domain + Glycosyl hydrolases 36 + Stealth protein CR2, conserved region 2 + Polyphosphate kinase + Dihydroorotate dehydrogenase, conserved site + Phytochrome + Protein of unknown function DUF167 + Glycoside hydrolase, family 6, conserved site + Nudix hydrolase 6-like + Chloroquine-resistance transporter-like + Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter + tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain + TonB box, conserved site + Aconitase/Iron-responsive element-binding protein 2 + Chromosomal replication control, initiator DnaA, conserved site + Solute-binding protein family 3, conserved site + Protein of unknown function DUF4838 + Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A + Intimal thickness related receptor, IRP + Clathrin, heavy chain, linker, core motif + CBF1-interacting co-repressor CIR, N-terminal domain + Ribonuclease E/G + 3-oxoacyl-[acyl-carrier-protein] synthase 3 + Biotin-protein ligase, N-terminal + ABC-type uncharacterised transport system + Dihydrofolate reductase + ALIX V-shaped domain + Protein of unknown function DUF445 + Ribosomal RNA large subunit methyltransferase J + Membrane fusogenic activity + Pilus assembly, Flp-type CpaB + Sucrose-phosphatase-like, N-terminal + Glycine-rich domain-containing protein-like + Lipin, N-terminal + Alpha 1,4-glycosyltransferase domain + Adhesin B + BPG-independent PGAM, N-terminal + Glycoside hydrolase, family 2, conserved site + UvrABC system, subunit B + Actin-related protein 2/3 complex subunit 4 + Archaeal/bacterial/fungal rhodopsins + Lipase, GDXG, putative serine active site + Tail completion protein + Phospholipid biosynthesis protein, PlsX-like + Quinolinate phosphoribosyl transferase, N-terminal + Protein of unknown function DUF846, eukaryotic + Protein of unknown function DUF847 + Bacterial alpha-L-rhamnosidase N-terminal + Xaa-Pro dipeptidyl-peptidase, C-terminal + Transcription factor NusA, N-terminal + Segregation and condensation protein A + Exonuclease VII, small subunit + ABC transporter substrate-binding protein PnrA-like + NMD3 + Protein phosphatase inhibitor 2 (IPP-2) + Septum formation initiator FtsL/DivIC + Ada-like domain + Pre-mRNA processing factor 4 (PRP4)-like + Ribosomal RNA large subunit methyltransferase F-like + NADH-plastoquinone oxidoreductase, chain 5 + Ribonuclease PH, conserved site + Rab3 GTPase-activating protein catalytic subunit + Ketopantoate reductase, C-terminal domain + ATP synthase, F1 complex, beta subunit + Proline-tRNA ligase, class IIa, archaeal-type + Heat shock protein HslU + Adenylosuccinate lyase C-terminal + Quinolinate phosphoribosyl transferase, C-terminal + Urease accessory protein UreF + Peptidase S53, activation domain + Succinyl-CoA ligase, alpha subunit + Histone H5 + Ribosomal protein L34Ae + Alkylhydroperoxidase AhpD core + Putative exonuclease, DNA ligase-associated + TPP-binding enzyme, conserved site + Ring-hydroxylating dioxygenase beta subunit + Phosphatidylglycerol lysyltransferase, C-terminal + Phosphoribosylformylglycinamidine synthase subunit PurQ + BFD-like [2Fe-2S]-binding domain + S-adenosylmethionine synthetase + Molybdate transporter 1/2 + 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site + Phosphatidylinositol 3-kinase, C2 domain + Adenylosuccinate synthase, active site + Flp/Fap pilin component + Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase + Protein CHAPERONE-LIKE PROTEIN OF POR1-like + Domain of unknown function DUF1747 + Protein-(glutamine-N5) methyltransferase, release factor-specific + Glycoside hydrolase family 9 + RNA ligase domain, REL/Rln2 + GTP cyclohydrolase II, RibA + FANCI solenoid 2 domain + Protein of unknown function DUF2842 + Structure-specific recognition protein + Thiol:disulfide interchange protein DsbD, N-terminal domain + Ubiquitin-activating enzyme E1, four-helix bundle + Domain of unknown function DUF4496 + Ribonuclease II/ribonuclease R + ComEC/Rec2-related protein + Ribonucleotide reductase class II vitamin B12-dependent, N-terminal domain + Frag1/DRAM/Sfk1 + GTPase HflX, N-terminal + Phosphotransferase system, HPr histidine phosphorylation site + Ribosomal protein L25, long-form + Dihydrodipicolinate reductase, conserved site + Aconitase B, swivel + Ribosomal protein S24e + Nodulin-like + Putative member of DMT superfamily + 2-phosphoglycolate phosphatase, eukaryotic + DNA helicase, DnaB-like, N-terminal + DNA helicase, DnaB-like, C-terminal + DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type + Domain of unknown function DUF4470 + 3-hydroxybutyrate dehydrogenase + GRIM-19 + Ribosomal protein S18, conserved site + PEP-utilising enzyme, active site + Transthyretin/hydroxyisourate hydrolase, superfamily + OB-fold nucleic acid binding domain + tRNA (C5-cytosine) methyltransferase, NCL1 + Ketopantoate reductase, N-terminal domain + Nucleotidyl transferase AbiEii toxin, Type IV TA system + Proline dehydrogenase PutA, domain II + Proteasome activator pa28, C-terminal domain + D-arabinono-1,4-lactone oxidase + Ribosomal protein L24e-related + Cilia BBSome complex subunit 10 + 4Fe4S-binding SPASM domain + Holo-[acyl carrier protein] synthase + Myo-inositol-1-phosphate synthase + CYTH domain + Phage gp6-like head-tail connector protein + Ribosomal protein L22e + Cysteine synthase CysK + Glucosamine-fructose-6-phosphate aminotransferase, isomerising + Cysteine synthase + DNA polymerase III, beta chain + CofG family + Peptidase S58, DmpA + Peptidase S51 + Protein of unknown function DUF308, membrane + Zinc finger, MIZ-type + Drug resistance transporter EmrB/QacA subfamily + Acetylornithine/Succinylornithine transaminase family + GTP-binding protein EngA + PHA accumulation regulator DNA-binding, N-terminal + Ribosomal protein S21 + Major spike protein G + Transcription factor DP, C-terminal + Sulphur oxidation protein SoxZ + VRR-NUC domain + Signal transduction histidine kinase, HWE region + HPr kinase/phosphorylase, C-terminal + Protein SirB1, N-terminal + Sirohaem synthase, N-terminal + Translation elongation factor P + Protein of unknown function DUF983 + Dim1 family + Preprotein translocase YajC + Uncharacterised protein family UPF0060 + Ribosomal protein L19, conserved site + Adenosine deaminase/editase + Transcription-repair-coupling factor, C-terminal domain + Protein of unknown function DUF3422 + Transcription antitermination protein, NusG + USP8 dimerisation domain + DNA-directed DNA polymerase, family B, conserved site + Ribosomal protein S17e + Leu/Phe/Val dehydrogenases active site + Protein of unknown function DUF4586 + GAD domain + DNA polymerase beta-like, N-terminal domain + PspA/IM30 + Domain of unknown function DUF35, OB-fold, C-terminal + Pyridoxamine 5'-phosphate oxidase + Protein of unknown function DUF974 + Sulphate adenylyltransferase + Protein of unknown function DUF4432 + DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type + Domain of unknown function DUF1993 + ParB/RepB/Spo0J partition protein family + MOB kinase activator family + Azospirillum phage Cd, Gp10 + Ribosome maturation factor RimP, N-terminal + Zinc-ribbon domain + Phosphohydrolase-associated domain + Death on curing protein + Domain of unknown function DUF4040 + Ribosomal RNA methyltransferase, Spb1, C-terminal + Bacterial DNA recombination protein RuvA + Photosystem I PsaD + Adenylosuccinate synthase, GTP-binding site + General secretory system II, protein E, N-terminal + GTP cyclohydrolase I, conserved site + AP endonuclease 1, conserved site + Cobaltochelatase subunit CobS N-terminal domain + 26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 + Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding + Na+/H+ antiporter subunit G + Serine dehydratase-like, alpha subunit + K+/H+ exchanger + Costars domain + tRNA threonylcarbamoyl adenosine modification protein TsaB + Glutamine synthetase type III N-terminal + Chromosomal replication initiator, DnaA C-terminal + Ribosomal protein L37ae/L37e + Spo11/DNA topoisomerase VI subunit A + Phosphomethylpyrimidine synthase + Transglutaminase-like cysteine peptidase, predicted + Autophagy-related protein 3 + Magnesium transporter MgtE + 10TM putative phosphate transporter, cytosolic domain + Cytochrome c oxidase, subunit I bacterial type + Arginine-tRNA-protein transferase, N-terminal + UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal + ABC transporter, haem export, CcmA + Zinc finger, DksA/TraR C4-type conserved site + Recombination protein RecR, C4-type zinc finger + AGR-C-984p-like domain + Zinc finger, CHY-type + Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit + Tensin phosphatase, C2 domain + Stc1 domain + DnaA N-terminal domain + DNA replication/recombination mediator RecO, N-terminal + Orn/Lys/Arg decarboxylase, major domain + Ribosomal protein S17, conserved site + AARP2CN + Domain of unknown function DUF1730 + Calcium/calmodulin-dependent protein kinase II, association-domain + MINDY deubiquitinase domain + Programmed cell death protein 2, C-terminal + Thymidylate synthase ThyX + RadC protein + Penicillin-binding protein 2 + Fibronectin, type II, collagen-binding + TFIID subunit TAF5, NTD2 domain + Adhesion lipoprotein + Adenosylcobinamide-GDP ribazoletransferase + Domain of unknown function DUF202 + Sodium/solute symporter, conserved site + Protein-tyrosine phosphatase-like, PTPLA + Secretory protein YscJ/FliF + rRNA-processing protein Fcf1/Utp23 + TRAP transporter, 4TM/12TM fusion protein + DnaJ homologue, subfamily C, member 28, conserved domain + Domain of unknown function DUF1990 + VTC domain + Ubiquitin-activating enzyme E1, C-terminal + Phasin + Potassium channel, voltage dependent, Kv3.3 + Malate dehydrogenase, active site + Mannose-6-phosphate isomerase, type I + TMEM70 family + Domain of unknown function DUF3333 + CbxX/CfqX, monofunctional + KDPG/KHG aldolase, active site 1 + PDCD5-related protein + TIP49, C-terminal + Bacterial virulence + Peptidase S8, subtilisin, Asp-active site + SWIB/MDM2 domain + 6-pyruvoyl tetrahydropterin synthase/QueD family protein + Transposase, IS116/IS110/IS902 + Heat-inducible transcription repressor HrcA, C-terminal + Bacterial lipid A biosynthesis acyltransferase + ATPase, V1 complex, subunit D + Photosystem II Psb28, class 1 + CcmH/CycL/Ccl2/NrfF family + Nucleolar complex protein 2 + Preprotein translocase SecG subunit + Inhibitor of growth protein, N-terminal histone-binding + Histidine acid phosphatase active site + Domain of unknown function DUF2147 + Protein of unknown function DUF2155 + Acetolactate synthase, small subunit, C-terminal + Endonuclease III, iron-sulphur binding site + Ribosomal protein L7Ae conserved site + Nitric oxide synthase, N-terminal + Prolipoprotein diacylglyceryl transferase + Sodium:alanine symporter + Phosphoribosyl pyrophosphate synthetase, conserved site + SRCR-like domain + Tudor domain + Formate dehydrogenase iron-sulphur subunit, Proteobacteria + Formate dehydrogenase, gamma subunit + Kynurenine formamidase + Probable epoxyqueuosine reductase QueH + tRNA wybutosine-synthesizing protein + Colicin V production, CvpA + Glycoside hydrolase, family 24 + LD-carboxypeptidase A, C-terminal domain + Uncharacterised protein family, transmembrane-17 + Ribokinase + Succinate dehydrogenase, cytochrome b subunit, conserved site + SLC12A transporter, C-terminal + Multiple antibiotic resistance (MarC)-related + DNA/RNA-binding protein Alba-like + Prefoldin beta-like + B domain of TMEM189, localisation domain + Potentiating neddylation domain + Bifunctional kinase-pyrophosphorylase + Organic solute transporter subunit alpha/Transmembrane protein 184 + Phosphoribosylformylglycinamidine cyclo-ligase + DNA polymerase lambda, fingers domain + Polyphosphate kinase C-terminal domain + Domain of unknown function DUF2062 + ABC transporter phosphate permease PstC, N-terminal domain + Sec7, C-terminal + NADH-quinone oxidoreductase, chain G, C-terminal + Formate/nitrite transporter, conserved site + ATP:guanido phosphotransferase, N-terminal + Acetohydroxy acid isomeroreductase, NADPH-binding domain + FAD-binding 8 + Phenylalanine-tRNA ligase, class II, N-terminal + NOT2/NOT3/NOT5 + PAZ domain + BAG domain + SRA-YDG + Beta-galactosidase trimerisation + DNA sulphur modification protein DndB + UbiC transcription regulator-associated + Acetaldehyde dehydrogenase + Bacterial sugar transferase + Acetoacetate decarboxylase beta barrel domain + N-acetylmuramoyl-L-alanine amidase domain + Kre9/Knh1 family + DNA-directed RNA polymerase, RBP11-like dimerisation domain + Protein of unknown function DUF1153 + Flavinator of succinate dehydrogenase + Inner centromere protein, ARK-binding domain + SF-assemblin + Glycine oxidase ThiO + Alanine racemase + Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype + Protein of unknown function DUF882 + MYCBP-associated protein + ATP synthase, F0 complex, subunit C, DCCD-binding site + Protein of unknown function DUF1476 + Histone acetyltransferase domain, MYST-type + Nascent polypeptide-associated complex NAC domain + FF domain + D-alanine--D-alanine ligase, C-terminal + Domain of unknown function DUF1977, DnaJ-like + SurA N-terminal + Guanylyl cyclase + Autophagy protein Atg8 ubiquitin-like + Acetaldehyde dehydrogenase, C-terminal + Kynureninase + Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain + Transcription initiation factor TAFII31 + Penicillin-binding protein, OB-like domain + Reticulon + Myxococcus cysteine-rich repeat + Conserved hypothetical protein CHP02231 + CbbQ/NirQ/NorQ, C-terminal + Ysc84 actin-binding domain + Bardet-Biedl syndrome 5 protein + YEATS + Pre-mRNA-splicing factor 38 + Catalase, mono-functional, haem-containing + Spindle assembly abnormal protein 6, N-terminal + Asn/Gln amidotransferase + P2X purinoreceptor extracellular domain + Ribonuclease PH, bacterial-type + Intraflagellar transport complex B protein 46 + KIF-1 binding protein + ARID DNA-binding domain + Conserved hypothetical protein CHP02186-related, transmembrane + Glycosyltransferase, GlcNAc + Phosphate-selective porin O/P + Inositol 1,4,5-trisphosphate/ryanodine receptor + Formate-tetrahydrofolate ligase, FTHFS + Histone H2B + NDUFAF3/Mth938 domain-containing protein + SWIRM domain + Zinc finger, HIT-type + Periplasmic copper-binding protein NosD, beta helix domain + Protein of unknown function DUF1285 + 5'(3')-deoxyribonucleotidase + 2-keto-3-deoxygluconate permease + DNA helicase, ATP-dependent, RecQ type, bacterial + Protein of unknown function DUF1491 + Coatomer beta subunit, appendage platform domain + NudC N-terminal domain + Protein of unknown function DUF2849 + RyR/IP3R Homology associated domain + Phage conserved hypothetical protein + Ureidoglycolate lyase + Peptidase M10, metallopeptidase + Biotin protein ligase, C-terminal + Stealth protein CR3, conserved region 3 + Stealth protein CR1, conserved region 1 + DNA helicase, Holliday junction RuvA type, domain I, bacterial + LIS1 homology motif + CheW-like domain + FtsK domain + Di-haem oxidoreductase, putative peroxidase + NADH-ubiquinone reductase complex 1 MLRQ subunit + YMGG-like Gly-zipper + DOMON domain + Nitrogen fixation protein FixH + DNA topoisomerase I, DNA binding, eukaryotic-type + CocE/Serine esterase + Fumarate hydratase, class II + 6-phosphogluconolactonase, DevB-type + Phosphate transport system permease protein 1 + D-alanine--D-alanine ligase + DNA repair protein RadA + Oligopeptide transporter, OPT superfamily + D-alanyl-D-alanine dipeptidase + Diacylglycerol kinase, accessory domain + Ribosomal protein L47, mitochondrial + Probable protein kinase UbiB + Protein of unknown function DUF4402 + H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 + 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal + Aconitase X catalytic domain, putative + Ribosomal protein S9, conserved site + Sigma 54 modulation/S30EA ribosomal protein, C-terminal + Metal-dependent protein hydrolase + Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site + Uncharacterised protein family UPF0324, prokaryote + Domain of unknown function DUF2083,transcriptional regulator + Uncharacterised domain SAYSvFN + FAE1/Type III polyketide synthase-like protein + Origin recognition complex, subunit 2 + Rod shape-determining protein MreC + Exonuclease VII, large subunit + TolB, N-terminal + Outer membrane protein assembly factor BamA + NusB antitermination factor + BRK domain + Lytic murein transglycosylase + Uncharacterised protein family UPF0149 + Tetraacyldisaccharide 4'-kinase + SAM-dependent methyltransferase RsmI, conserved site + Ubiquitin activating enzyme, alpha domain + Fructose-1,6-bisphosphatase + Peptidase C45 + Uncharacterised conserved protein UCP030820 + Toxic anion resistance + N-acetyltransferase RimI/Ard1 + Chloroplast protein import component Tic20 + Aspartate-tRNA ligase, type 1 + Toxin-antitoxin system, RelE/ParE toxin family + Cell morphogenesis protein N-terminal + Protein of unknown function DUF3754 + Transcription initiation factor TFIID subunit 1, domain of unknown function + Glu-tRNAGln amidotransferase C subunit + Glycoside hydrolase, family 39 + Cytochrome c/c1 haem-lyase + Catalase active site + Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase + Methionine biosynthesis MetW + Transcription termination factor NusA + Domain of unknown function DUF559 + Molybdopterin oxidoreductase, 4Fe-4S domain + Vitamin K-dependent gamma-carboxylase + Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like + Potassium uptake protein TrkA + Asparaginase/glutaminase-like + Ubiquinone biosynthesis protein Coq7 + D-Tyr tRNAtyr deacylase-like domain + RNase L inhibitor RLI, possible metal-binding domain + Photosystem II cytochrome b559, N-terminal + U1-C, C2H2-type zinc finger + ABC transport permease subunit MlaE, Proteobacteria + Uncharacterised protein family UPF0592 + Protein of unknown function DUF463, YcjX-like protein + Nrap protein, domain 4 + Deoxynucleoside kinase domain + Sodium/sulphate symporter, conserved site + Thymidylate synthase, active site + NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 + Legume-like lectin + CcmE/CycJ protein + Uncharacterised protein family UPF0012, conserved site + Foie gras liver health family 1 + LPS export ABC transporter permease LptG + N-carbamoylputrescine amidase + Cytochrome c oxidase, subunit II + p-Aminobenzoyl-glutamate transport protein AbgT + Poly(A) polymerase, central domain + Organic solvent tolerance protein, C-terminal + D-3-phosphoglycerate dehydrogenase + TH1 protein + Malate:quinone-oxidoreductase + Pilus formation protein, N-terminal + Alpha-N-acetylglucosaminidase, tim-barrel domain + Tryptophan synthase, alpha chain + Protein of unknown function DUF92, TMEM19 + DNA polymerase III epsilon subunit, exonuclease domain + Predicted integral membrane protein DUF2189 + UvrABC system, subunit C + Isocitrate dehydrogenase NADP-dependent + Conserved hypothetical protein CHP00275, flavoprotein HI0933-like + Calcium/proton exchanger CAX + Protein of unknown function DUF3578 + Clathrin, heavy chain, linker + DDHD domain + THO complex, subunit 5 + Peptidase M76, ATP23 + Conserved hypothetical protein CHP02096 + Protein of unknown function DUF3011 + Domain of unknown function DUF4130 + Organic hydroperoxide resistance protein famiy + LPS-assembly lipoprotein LptE + P-type ATPase, subfamily IV + Acyl-CoA thioester hydrolase YbgC/YbaW family + C-terminal associated domain of TOPRIM + GTP binding protein, second domain + AMP-activated protein kinase, glycogen-binding domain + Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain + Signal transduction histidine kinase, internal region + Domain of unknown function DUF1126 + Holliday junction DNA helicase ruvB, N-terminal + DNA helicase, Holliday junction RuvB type, C-terminal + Aromatic amino acid hydroxylase, C-terminal + Flagellar basal body rod protein, conserved site + F-actin capping protein, beta subunit, conserved site + Vesicle tethering protein Uso1/P115-like , head domain + Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal + RadC-like JAB domain + UDP-N-acetylglucosamine 2-epimerase WecB-like + Cellulose/chitin-binding protein, N-terminal + Glycoside hydrolase, family 3, active site + Protocatechuate 3,4-dioxygenase, beta subunit + RNA polymerase-binding transcription factor DksA + Phosphopantetheine-protein transferase domain + Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ + Outer membrane lipoprotein carrier protein LolA-like + Apolipoprotein N-acyltransferase + Acylphosphatase-like domain + Dihydrofolate reductase domain + NADH:ubiquinone oxidoreductase chain 4, N-terminal + Ancestral coatomer element 1, Sec16/Sec31 + Mg chelatase-related protein, C-terminal domain + Deoxyuridine triphosphate nucleotidohydrolase + Ribonucleotide reductase regulator NrdR-like + Eukaryotic porin/Tom40 + DHAP synthase, class 1 + Blood group Rhesus C/E/D polypeptide + Photosystem II cytochrome b559, conserved site + Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic + Vacuolar protein sorting-associated protein 62 + Ribosomal protein S8e/ribosomal biogenesis NSA2 + ATP-dependent DNA ligase, PP_1105 family + FIST, C-domain + Dense granule Gra7 protein + Protein of unknown function DUF227 + Chalcone/stilbene synthase, N-terminal + Acetyl-CoA carboxylase, alpha subunit + 30S ribosomal protein + Haemerythrin-like + Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal + Domain of unknown function DUF4483 + Archaeophage PsiM2, terminase large subunit + Proteasome component Ecm29 + Protein of unknown function DUF583 + Helicase/SANT-associated domain + Cytidylate kinase domain + Mon2, dimerisation and cyclophilin-binding domain + Thioredoxin reductase + Chromosome segregation/condensation protein ScpB + Translation initiation factor IF-1 + ROSMUCR transcriptional regulator + RHD3/Sey1 + Phosphatidylserine decarboxylase, archaeal-type + Protein LOW PSII ACCUMULATION 1-like + Zinc finger, DPH-type + Transport and Golgi organisation protein 2 + DNA recombination and repair protein RecA + Large-conductance mechanosensitive channel, conserved site + Ribosomal protein L32e + Glycoside hydrolase, family 29 + Photosystem antenna protein-like + Outer membrane protein assembly factor BamD + DNA ligase, OB-like domain + Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein + Torus domain + Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain + GCR1-cAMP receptor + Protein C10 + Ceramide glucosyltransferase + Alanine dehydrogenase + DNA translocase FtsK, 4TM region + Mannose-6-phosphate isomerase + Ketol-acid reductoisomerase + Isopentenyl-diphosphate delta-isomerase, type 1 + Uncharacterised protein family UPF0193 + Phosphocarrier protein HPr-like + Protein of unknown function DUF1217 + Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain + Coatomer beta subunit, C-terminal + TB2/DP1/HVA22-related protein + Oxidoreductase, molybdopterin binding site + Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain + Putative sensory transduction regulator YbjN + S-adenosylmethionine decarboxylase, core + Proline-tRNA ligase, class II, C-terminal + Nitrogen regulatory protein PII, conserved site + Nuclear transcription factor Y subunit A + Photosystem I PsaA/PsaB + Photosynthetic reaction centre, L/M + Haem exporter protein D (CcmD) + Peptidase U32 + Protein of unknown function DUF1810 + Ion channel regulatory protein, UNC-93 + Protein of unknown function DUF901 + Tetracycline transcriptional regulator, TetR-related, C-terminal + Alanine racemase, C-terminal + Lanthionine synthetase C-like + Rad4/PNGase transglutaminase-like fold + Formin, FH3 domain + Protein prenyltransferase, alpha subunit + MATH/TRAF domain + Ubiquitin-activating enzyme E1, FCCH domain + Leucine zipper transcription factor-like protein 1 + UDP-N-acetylmuramate--L-alanine ligase + Endonuclease III + UDP-N-acetylglucosamine 1-carboxyvinyltransferase + Ribosomal protein L26/L24, eukaryotic/archaeal + Clp protease, ATP-binding subunit ClpX + Monothiol glutaredoxin-related + Mg chelatase-related protein + Photosystem II PsbO, manganese-stabilising + DNA polymerase III, beta chain, central + DNA polymerase III, beta chain, N-terminal + DNA polymerase III, beta chain, C-terminal + 30S ribosomal protein S17 + Translation initiation factor IF2/IF5, N-terminal + NLE + RecG, wedge domain + Zinc finger, ClpX C4-type + 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 1 + Flagella basal body P-ring formation protein FlgA, C-terminal + Ribonuclease toxin, BrnT, of type II toxin-antitoxin system + Domain of unknown function DUF448 + Peptidyl-arginine deiminase, Porphyromonas-type + Methylmalonate-semialdehyde dehydrogenase + Cytochrome c-type biogenesis protein CcmB + RNA polymerase Rpb2, domain 4 + RNA polymerase Rpb2, domain 5 + 6-phosphogluconate dehydrogenase, C-terminal + DNA polymerase V + Flp pilus assembly protein RcpC/CpaB domain + Domain of unknown function DUF4704 + DNA repair protein MmcB-like + MRG domain + Ribonuclease CAF1 + Drug resistance transporter Bcr/CmlA subfamily + Formyltetrahydrofolate deformylase + RelA/SpoT family + Lon protease, bacterial/eukaryotic-type + NAD-dependent DNA ligase, conserved site + Protein of unknown function DUF3445 + DNA replication factor RFC1, C-terminal + UDP-galactopyranose mutase, C-terminal + DDE domain + Replication protein A, OB domain + Carboxyltransferase domain, subdomain A and B + Large ribosomal RNA subunit accumulation protein YceD + Endolytic murein transglycosylase + Polysaccharide biosynthesis protein, C-terminal domain + L-lactate/malate dehydrogenase + Copper homeostasis CutC domain + Trafficking protein particle complex subunit 2 + Phosphodiesterase MJ0936/Vps29 + Glycosyl hydrolase family 36, N-terminal + Glycosyl hydrolase family 36, C-terminal + Protein of unknown function DUF1009 + Yjdj-type Gcn5-related N-acetyltransferase + Katanin p80 subunit, C-terminal + DNA topoisomerase I, bacterial-type + DNA topoisomerase IV, subunit B, Gram-negative + Tumour necrosis factor-like domain + Riboflavin kinase, bacterial + Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal + SecE subunit of protein translocation complex + Succinate--CoA synthetase, beta subunit + Phosphoribosylglycinamide formyltransferase + DNA helicase, Holliday junction RuvB type + UvrABC system subunit A + rRNA small subunit methyltransferase I + Beta-lactamase, class-A active site + XPA C- terminal + GxxExxY protein + Integral membrane protein YjbE + Protein of unknown function DUF2892 + Coiled-coil domain-containing protein 22 + Nuclear pore localisation protein Npl4, ubiquitin-like domain + Complement Clr-like EGF domain + Intramolecular chaperone auto-processing domain + Transposase TnpC, homeodomain + Double Cache domain 1 + Protein of unknown function DUF454 + LexA-binding, inner membrane-associated putative hydrolase + Transcription elongation factor GreA + Glutathione synthase domain + Phospho-N-acetylmuramoyl-pentapeptide transferase + DNA-directed DNA polymerase, family B + Urease, gamma/gamma-beta subunit + Succinate dehydrogenase, flavoprotein subunit + Acetoacetyl-CoA reductase + Ribosomal protein S3, conserved site + Transketolase, bacterial-like + RNA 3'-terminal phosphate cyclase domain + Nuclear pore localisation protein NPL4, C-terminal + Rhodanase, C-terminal + Membrane bound O-acyl transferase, MBOAT + Protein of unknown function DUF819 + Domain of unknown function DUF815 + DEAD/H associated + Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site + Urease active site + Ketopantoate reductase ApbA/PanE + DNA-directed RNA polymerase, omega subunit + Phage shock protein, PspC, N-terminal + Aconitase X swivel domain, putative + Cholinesterase + L-asparaginase II + Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase + Dihydroorotate dehydrogenase, class 2 + GH3 family + Reduced folate carrier + Ribosome recycling factor + Urease accessory protein UreD + Single-stranded DNA-binding protein + UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase + Domain of unknown function DUF4062 + Myristoyl-CoA:protein N-myristoyltransferase, N-terminal + RNA methyltransferase TrmH family + EGF-like calcium-binding, conserved site + Acetolactate synthase, large subunit, biosynthetic + Conserved hypothetical protein CHP02300, FYDLN acid + Pyridoxine kinase + Potassium-transporting ATPase A chain + Cofactor assembly of complex C subunit B, CCB2/CCB4 + Pseudouridine-5'-phosphate glycosidase + Spo11/DNA topoisomerase VI, subunit A, N-terminal + Invasion protein B + MlaA lipoprotein + Peptidase family S66 + Meiosis-expressed gene 1 protein + UV excision repair protein Rad23 + Holliday junction DNA helicase RuvA, C-terminal + 4-hydroxybenzoate polyprenyltransferase + Histidinol-phosphate phosphatase, putative, inositol monophosphatase + Phosphoribosylformylglycinamidine synthase subunit PurS + Polysaccharide chain length determinant N-terminal domain + Potassium transporter + Ribosomal protein L22/L17, conserved site + Alpha tubulin + Transcription factor, MADS-box + Glycosyl transferase, ALG6/ALG8 + 14-3-3 protein, conserved site + DNA recombination and repair protein RecA, C-terminal + Ornithine cyclodeaminase, N-terminal + DNA helicase, DnaB type + Cytoplasmic FMR1-interacting + NUC153 + tRNA-specific adenosine deaminase + Glycosyl hydrolase family 32, C-terminal + D-aminoacyl-tRNA deacylase DTD + Multi-copper polyphenol oxidoreductase + Ribosomal protein S3Ae + Alpha-2-macroglobulin + DGQHR-containing domain + PhnA protein, C-terminal + Ribosomal L28e/Mak16 + Rab5-interacting protein family + Primosome PriB/single-strand DNA-binding + Protein of unknown function DUF350 + Sas10/Utp3/C1D + N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase + Cwf19-like protein, C-terminal domain-2 + Gtr1/RagA G protein + Fumarase C, C-terminal + Cwf19-like, C-terminal domain-1 + Oxysterol-binding protein + NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site + Histone chaperone ASF1-like + tRNA (guanine-N1-)-methyltransferase, bacteria + Lysine-tRNA ligase, class II + Proline-tRNA ligase, class IIa + Urease, alpha subunit + Ribosomal protein S12 methylthiotransferase RimO + Di-trans-poly-cis-decaprenylcistransferase-like, conserved site + Host attachment protein + Formate dehydrogenase, transmembrane + Anhydro-N-acetylmuramic acid kinase + Tctex-1 + Mitochondrial pyruvate carrier + RapZ-like family + Phosphatase PHOSPHO-type + Cobalt transporter subunit CbtA, putative + Cobalt transporter subunit CbtB, putative + Histidinol dehydrogenase, conserved site + F-actin-capping protein subunit beta + Glucosidase II beta subunit-like + Activator of Hsp90 ATPase homologue 1-like + Starch synthase, catalytic domain + 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 + Lipoyl synthase + NAD(+) synthetase + ASCH domain + Sulfur carrier protein FdhD + Regulatory protein RecX + HTH-type transcriptional regulator AraC-type, N-terminal + Condensin complex subunit 1, C-terminal + ABC-2 family transporter protein + Phosphotransferase system, enzyme I-like + Domain of unknown function DUF2382 + Clathrin adaptor, mu subunit, conserved site + Peptidase S9, serine active site + Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family + Glyoxalase-like domain + SIMIBI class G3E GTPase, ArgK/MeaB + Hydroxymethylglutaryl-CoA reductase, N-terminal + Domain of unknown function DUF4201 + Polyphosphate kinase 2, PA0141 + CDK5 regulatory subunit-associated protein 3 + Protein of unknown function DUF3089 + Integral membrane protein EMC3/TMCO1-like + 4-hydroxy-2-oxovalerate aldolase + Alanine racemase, pyridoxal-phosphate attachment site + Formate-tetrahydrofolate ligase, FTHFS, conserved site + Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase + Putative Flp pilus-assembly TadG-like, N-terminal + Transcription factor zinc-finger + FKBP12-rapamycin binding domain + Condensin complex subunit 2/barren + Dihydroxy-acid dehydratase + Biotin--acetyl-CoA-carboxylase ligase + ATPase MipZ + Inner membrane protein YedI + Sulphotransferase Stf0, domain + Pyridoxamine 5'-phosphate oxidase, Alr4036 family, FMN-binding domain + PhnB-like + Vitamin K epoxide reductase + DNA recombination protein RecR + Flagellar M-ring C-terminal + RNA cap guanine-N2 methyltransferase + GPI mannosyltransferase 2 + Small-subunit processome, Utp21 + Protein of unknown function DUF4419 + BCS1, N-terminal + Glutamate--cysteine ligase, GCS2 + Thioredoxin/glutathione reductase selenoprotein + Glycerol-3-phosphate acyltransferase, PlsY + Rhodopsin, retinal binding site + Inositol oxygenase + LexA repressor, DNA-binding domain + Peptidase S24, LexA-like + Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal + Ragulator complex protein LAMTOR3 + tRNA synthetase, B5-domain + eRF1 domain 3 + eRF1 domain 2 + eRF1 domain 1/Pelota-like + Adenylosuccinate lyase + Homoserine/serine acetyltransferase MetX-like + MetA family + Anion-transporting ATPase-like domain + Domain of unknown function DUF4172 + Protein of unknown function DUF3703 + Glycosyl hydrolase family 32, N-terminal + Ubiquinol-cytochrome c chaperone/UPF0174 + SRP-independent targeting protein 3 + Photosystem I PsaE, reaction centre subunit IV + Cytosolic fatty-acid binding + Peptidase S49, serine-peptidase prokaryotes + Survival protein SurE-like phosphatase/nucleotidase + Protein-L-isoaspartate(D-aspartate) O-methyltransferase + Succinyl-CoA synthetase, beta subunit, conserved site + Serine acetyltransferase, N-terminal + Conserved oligomeric Golgi complex subunit 6 + tRNA intron endonuclease, catalytic domain-like + Lipoyl synthase, N-terminal + UDP-N-acetylglucosamine 2-epimerase domain + TMEM144 + Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase + Ribonuclease H1, N-terminal + Replication protein A, C-terminal + DWNN domain + SMc04008-like domain + Protein of unknown function DUF1118 + Alpha-L-rhamnosidase, concanavalin-like domain + Ubiquitin-fold modifier 1 + TRAP transporter solute receptor, DctP family + Ferredoxin, C-terminal + Peptidase M1, alanyl aminopeptidase + Diphthamide synthesis DPH1/DPH2 + Initiation factor 2 associated domain, bacterial + RNA ligase T4 Rnl1, N-terminal + Homoserine kinase + Beta-lactamase, class-A + Domain of unknown function DUF1793 + CWC16 protein + tRNA pseudouridine synthase II, TruB + AsmA + Electron transfer flavoprotein subunit alpha, conserved site + Tryptophan synthase, alpha chain, active site + Pyruvate kinase, active site + L-asparaginase, N-terminal + Protein-only RNase P, C-terminal + Murein tetrapeptide carboxypeptidase, N-terminal domain + Superoxide dismutase, Nickel-type + Tex-like protein, N-terminal + Protein of unknown function DUF1997 + DEAD/DEAH-box helicase, putative + Na+/H+ antiporter MnhB subunit-related protein + Desulfoferrodoxin, ferrous iron-binding domain + Ku70/Ku80, N-terminal alpha/beta + PhoPQ-activated pathogenicity-related protein, PqaA type + Prokaryotic glutathione synthetase, N-terminal + FAM227 Protein + Purine-cytosine permease + GUCT + Rrp44-like cold shock domain + Exosome complex exonuclease RRP44, S1 domain + NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 + VIT domain + Hydroxymethylglutaryl-CoA synthase, eukaryotic + Succinate dehydrogenase, cytochrome b556 subunit + Guanine deaminase + Molybdopterin oxidoreductase, prokaryotic, conserved site + Arsenate reductase + CobB/CobQ-like glutamine amidotransferase + Peptidase C26 + RNA polymerase Rpb2, OB-fold + Nicotinate-nucleotide pyrophosphorylase + 4-diphosphocytidyl-2C-methyl-D-erythritol kinase + Protein of unknown function DUF1285, beta-roll domain + GOLD domain + Domain of unknown function DUF262 + Yippee/Mis18/Cereblon + SLIDE domain + Translation elongation factor SelB, winged helix, type 2 + WYL domain + Vacuolar protein sorting protein 26 related + Microcystin LR degradation protein MlrC, N-terminal + Uncharacterised hydrolase TatD-type + Luciferase family oxidoreductase, group 1 + NOP5, N-terminal + Actin, conserved site + DhaL domain + Alcohol dehydrogenase, iron-type + Large-conductance mechanosensitive channel + Citron homology (CNH) domain + DNA recombination RmuC + Alkyl sulfatase dimerisation domain + Alkyl sulfatase, C-terminal + Phosphopantetheine adenylyltransferase + Polyphosphate kinase middle domain + Protein of unknown function DUF192 + Extensin-like, C-terminal + Profilin + Bacteriophage/plasmid primase, P4, C-terminal + Aminopeptidase P, N-terminal + Growth factor receptor domain 4 + Phytoene desaturase + Carotenoid/retinoid oxidoreductase + Di-haem cytochrome c peroxidase + ABC-type transport auxiliary lipoprotein component + Rhamnose/fucose mutarotase + DNA gyrase inhibitor YacG + Protein of unknown function DUF72 + Intra-flagellar transport protein 57 + DNA repair metallo-beta-lactamase + DNA polymerase III, gamma subunit, domain III + AMP nucleoside phosphorylase, N-terminal + Phosphoinositide 3-kinase, accessory (PIK) domain + Ferroporti-1 + YhhN-like + Vps54-likeVacuolar protein sorting-associated protein 54, C-terminal + Dihydroorotase homodimeric type + Chalcone isomerase, 3-layer sandwich + Nitrilase/cyanide hydratase, conserved site + Limonene-1,2-epoxide hydrolase + Lycopene cyclase, beta/epsilon + Nucleolar protein 14 + YTH domain + Epoxyqueuosine reductase QueG + Lipoxygenase, C-terminal + TPX2 central domain + Heat-inducible transcription repressor HrcA + Penicillin amidase type, domain1 + Lysozyme domain + Haem-degrading + Signal-recognition particle receptor FtsY + RNA methyltransferase, RsmD + Capsule synthesis protein, CapA + Carbonic anhydrase, cadmium-binding + HNH nuclease + Formate dehydrogenase, delta subunit + PRMT5 arginine-N-methyltransferase + DREV methyltransferase + ATPase, OSCP/delta subunit, conserved site + SUF system FeS cluster assembly associated + Tol-Pal system, TolQ + Glutathione synthetase, prokaryotic + Protein DJ-1 + Peptidoglycan-associated lipoprotein + Alpha/beta-hydrolase, N-terminal domain + Post-segregation antitoxin CcdA + Ig-like SoxY domain + Primosomal protein N' + PdxA family + O-acyltransferase, WSD1, N-terminal + Bud13 + Phosphotransferase system, mannose-type IIA component + Ran binding domain + EGF-type aspartate/asparagine hydroxylation site + Cof family + Homeobox KN domain + Male sterility, NAD-binding + Ferric reductase, NAD binding domain + Putative rhamnosyl transferase + Vps52 + Nuclear pore protein 84/107 + UDP-N-acetylenolpyruvoylglucosamine reductase + Mo25-like + Protein of unknown function DUF1761 + Uncharacterised protein family C20orf85 + Urate oxidase N-terminal + Lipid droplet-associated hydrolase + Lipoprotein-releasing system transmembrane protein LolC/E + Down-regulated-in-metastasis protein + Protein phosphatase 2A, regulatory B subunit, B56 + Glycosyl transferase, family 43 + Sjoegren syndrome/scleroderma autoantigen 1 + Protein of unknown function DUF1178 + G-protein, beta subunit + DNA-directed RNA polymerase, N-terminal + Methylated-DNA-[protein]-cysteine S-methyltransferase, active site + Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase + Clathrin, heavy chain/VPS, 7-fold repeat + Flagellar motor protein MotA, conserved site + Prephenate dehydrogenase + Catalase-peroxidase haem + DNA-directed RNA polymerase beta subunit, bacterial-type + Glycoside hydrolase, family 25 + Ribonuclease E inhibitor RraA/RraA-like protein + Leucine-rich glioma-inactivated , EPTP repeat + Twin-arginine translocation protein TatB + Uracil-DNA glycosylase family 4 + C-type lysozyme inhibitor + Protein of unknown function DUF2125 + Heat shock protein Hsp33, C-terminal + Chlorophyllase + DNA metabolism protein, putative + Trafficking protein particle complex subunit + DNA repair protein Rad52/59/22 + Glutaredoxin, GrxC + Ubiquitin-activating enzyme E1 + Cyclic nucleotide-regulated ion channel, N-terminal domain + Cardiolipin synthase N-terminal + Ribosomal protein L29, conserved site + Erythromycin esterase + RNA-binding protein Hfq + Uncharacterised conserved protein UCP032025 + Histidine-specific methyltransferase, SAM-dependent + Alpha-L-arabinofuranosidase B, catalytic + Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family + Protein-export membrane protein SecF, bacterial + dTDP-4-dehydrorhamnose reductase family + Phenylalanine-tRNA ligase, class IIc, beta subunit + Selenophosphate synthetase + Transcription activator GCR1-like domain + Heparinase II/III-like + Protein of unknown function DUF3987) + Growth arrest-specific protein 8 + FAD synthetase + Transcription antitermination protein, NusG, bacteria, conserved site + 7-carboxy-7-deazaguanine synthase, Cx14CxxC-type + Alpha-N-acetylglucosaminidase, N-terminal + NSF attachment protein + EGF-like domain + VCBS repeat + Protein of unknown function DUF501 + Nuclear transport factor 2 + Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site + Trigger factor + Protein of unknown function DUF2071 + Protein of unknown function DUF3553 + Urease alpha-subunit, N-terminal domain + Isopropylmalate dehydrogenase + Methylmalonyl-CoA epimerase + Gcn5-related N-acetyltransferase (GNAT) domain, ATAT-type + PSP, proline-rich + Clan AA aspartic peptidase, C-terminal + 16S rRNA processing protein RimM + DNA-binding protein Dps, conserved site + Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 + Rab GDI protein + Transposase IS66, Orf2 + Uncharacterised conserved protein UCP016719 + Integration host factor, alpha subunit + Delta-1-pyrroline-5-carboxylate dehydrogenase 3 + HEAT repeat associated with sister chromatid cohesion protein + Beta-lactamase hydrolase-like + Modification methylase HemK + Lsm14-like, N-terminal + Aromatic amino acid lyase + NECAP, PHear domain + Protein of unknown function DUF4079 + Alpha-N-acetylglucosaminidase, C-terminal + Frataxin/CyaY + Optic atrophy 3-like + HopJ type III effector protein + Aromatic-L-amino-acid decarboxylase + Glycine cleavage system T protein + Hyaluronan-mediated motility receptor, C-terminal + Protein of unknown function DUF1467 + Replication factor A, C-terminal + Polynucleotide kinase 3 phosphatase + Domain of unknown function DUF4964 + Co-chaperone DjlA, N-terminal + NTP pyrophosphohydrolase MazG + V-ATPase proteolipid subunit C, eukaryotic + Glutamate--cysteine ligase, plant-type + Quinone oxidoreductase PIG3 + Uncharacterised protein family UPF0758, conserved site + Fructose-1,6-bisphosphatase, active site + Urease, beta subunit + Proteasome/cyclosome repeat + Metallophosphoesterase, YmdB-like + Toxin HigB-like + Cofactor assembly of complex C subunit B, CCB1 + Zinc-finger, NAD-dependent DNA ligase C4-type + mRNA capping enzyme, catalytic domain + Domain of unknown function DUF4136 + RecQ mediated genome instability protein, N-terminal + Glutaredoxin 2, C-terminal + LytTR DNA-binding domain + Protein of unknown function DUF3572 + HAD-superfamily hydrolase,subfamily IIIA + BCCT transporter family + Flagellar M-ring protein FliF + Delta-aminolevulinic acid dehydratase, active site + Protein of unknown function DUF3576 + Glutathione synthase, N-terminal, eukaryotic + Chromate transporter, long chain + Domain of unknown function DUF1115 + Dullard phosphatase domain, eukaryotic + Steroid delta5-4-isomerase + CDC50/LEM3 family + Pyridoxamine 5'-phosphate oxidase, conserved site + 4-hydroxyphenylpyruvate dioxygenase + Lipid/polyisoprenoid-binding, YceI-like + Headcase protein + Pyrrolo-quinoline quinone-like domain + Urease nickel binding site + Calcium release-activated calcium channel protein + Translation initiation factor IF2/IF5 + Flagellar P-ring protein + Cellulose-binding domain, fungal + Flagellar L-ring protein + Lumazine synthase + Protocatechuate 3,4-dioxygenase beta subunit, N-terminal + Enhancer of rudimentary + Citrate synthase, type I + Flagellar C1a complex subunit C1a-32 + Translation initiation factor, beta propellor-like domain + G protein alpha subunit, helical insertion + Branched-chain amino acid aminotransferase I + Threonine dehydratase, biosynthetic + Branched-chain amino acid aminotransferase II + Mut7-C RNAse domain + Glycoside hydrolase, family 8 + Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA + Major capsid protein GpE + Protein of unknown function DUF2171 + 6-phosphogluconate dehydratase + Signal recognition particle protein Ffh + Acetolactate synthase, small subunit + ABC transporter, ATP-binding protein, ChvD + Coenzyme A transferase binding site + Ataxin-10 domain + Protein of unknown function DUF3035 + Domain of unknown function DUF4167 + Domain of unknown function DUF5110 + Ornithine cyclodeaminase/mu-crystallin + Protein of unknown function DUF721/UPF0232 + Dihydrodipicolinate reductase + PilZ domain + DNA-directed DNA polymerase, family A, conserved site + Translation elongation factor, IF5A, hypusine site + Light-dependent protochlorophyllide reductase + DmpG-like communication + Glyoxalase I, conserved site + Peptide chain release factor 1 + Replication factor A protein 1 + Splicing factor, RBM39-like + Zinc finger, CCCH-type, TRM13 + BLUF domain + Copper centre Cu(A) + Wax synthase domain + DoxX family + Nucleotide exchange factor Fes1 + FO synthase, subunit 2 + Udp N-acetylglucosamine O-acyltransferase, C-terminal + Photosystem I PsaA/PsaB, conserved site + DNA recombination/repair protein RecA, conserved site + 3-phosphoshikimate 1-carboxyvinyltransferase + Cytidine deaminase, homotetrameric + dNTP triphosphohydrolase + UDP-N-acetylmuramoylalanine-D-glutamate ligase + Inositol-pentakisphosphate 2-kinase + ATPase, AAA-3 + Domain of unknown function DUF625 + Nucleoside diphosphate kinase, active site + Membrane insertase YidC, N-terminal + Phosphotransferase system, enzyme I N-terminal + Translation elongation factor IF5A + EGF-like calcium-binding domain + Domain of unknown function DUF3385, target of rapamycin protein + Translocation and assembly module TamB + DNA polymerase III chi subunit, HolC + DNA primase, phage/plasmid + Alpha-L-rhamnosidase C-terminal domain + MltA-interacting MipA + Succinate dehydrogenase/fumarate reductase, flavoprotein subunit + PTS EIIA type-2 domain + NatC N(alpha)-terminal acetyltransferase, Mak10 subunit + Protein of unknown function DUF4864 + Transcription factor TFIIB + Domain of unknown function DUF4456 + Protein of unknown function DUF4486 + Glycoside hydrolase, family 65, central catalytic + Glycoside hydrolase, family 65, N-terminal + U2 auxiliary factor small subunit + TATA box binding protein associated factor (TAF) + Basic leucine zipper domain, Maf-type + Vacuolar fusion protein Mon1 + Phosphoenolpyruvate carboxylase, Lys active site + Protein of unknown function DUF829, TMEM53 + Hypothetical PA1492 domain + Anaphase-promoting complex subunit 4 long domain + Ribosomal protein L15e core domain + SKP1 component, POZ domain + SKP1 component, dimerisation + Siroheme synthase, central domain + E3 ubiquitin ligase, UBR4 + F-type ATP synthase subunit B-like, membrane domain + Arsenite-resistance protein 2 + Uncharacterised membrane protein YitT + Cyclodeaminase/cyclohydrolase + RNA polymerase sigma factor 54, core-binding + Carbohydrate-selective porin OprB + DNA-directed RNA polymerase, M/15kDa subunit + IMS import disulfide relay-system, CHCH-CHCH-like Cx9C + Carbamoyltransferase, C-terminal + Condensin-2 complex subunit H2, C-terminal + TRAPP II complex, Trs120 + Small-subunit processome, Utp13 + RNA polymerase II-associated protein 1, N-terminal + TATA-binding protein interacting (TIP20) + E2 binding + Photosystem I PsaB + Glycoside hydrolase, family 43 + Photosystem II cytochrome b559, beta subunit + 3(2),5 -bisphosphate nucleotidase, bacterial + Photosystem I PsaA + Protein kinase C-like, phorbol ester/diacylglycerol-binding domain + GWT1 + Protein of unknown function DUF1077, TMEM85 + L-seryl-tRNA selenium transferase-like + Lipopolysaccharide assembly protein A domain + WD repeat protein mio, zinc-ribbon like domain + Alginate lyase domain + Intron-binding protein aquarius, N-terminal + DNA mismatch repair protein MutS + Archease domain + PTHB1, C-terminal domain + Nicastrin + SAM-dependent methyltransferase, NodS-related + Conserved oligomeric Golgi complex subunit 7 + Peroxisome biogenesis factor 1, N-terminal, psi beta-barrel fold + FAM192A/Fyv6, N-terminal + Mesoderm development candidate 2 + Organic solute carrier protein 1 + GTP-binding protein OBG, C-terminal + Cell division topological specificity factor MinE + tRNA-dihydrouridine synthase, TIM-barrel, NifR3 + Beta propeller domain-containing family + AATF leucine zipper-containing domain + ABC transporter, ATPase, putative + Transcription elognation factor Eaf, N-terminal + Gene transfer agent, major tail protein + Domain of unknown function DUF3495 + RecB family nuclease, TM0106, putative + Malate dehydrogenase, type 1 + Recombination protein RecR, conserved site + NADPH-dependent 7-cyano-7-deazaguanine reductase QueF + Uridylate kinase, bacteria + Apoptosis-antagonizing transcription factor, C-terminal + CDP-alcohol phosphatidyltransferase, C-terminal + DNA topoisomerase I, domain 1 + Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain + Rit1, N-terminal domain + Lung seven transmembrane receptor-like + Zinc finger, TFIIB-type + Uncharacterised protein family Ycf36 + DNA ligase D, 3'-phosphoesterase domain + Protein phosphatase 2A regulatory subunit PR55 + WW domain binding protein 11 + S-adenosylmethionine decarboxylase, conserved site + Putative threonine/serine exporter + Malonyl CoA-acyl carrier protein transacylase, FabD-type + 3D domain + Pescadillo + ALG11 mannosyltransferase, N-terminal + Phosphoribosylformylglycinamidine subunit PurL + Amino acid adenylation domain + HAD-superfamily hydrolase, subfamily IB, SerB1-like + Phosphoribosylformylglycinamidine synthase + xxxLxxG heptad repeat + Acetophenone carboxylase beta subunit/Acetone carboxylase gamma subunit + SseB protein N-terminal domain + Type IV conjugative transfer system, protein TraL + Signal peptidase complex subunit 3 + Abnormal spindle-like microcephaly-associated protein, ASH domain + Putative TPR-like repeat + Domain of unknown function DUF775 + Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 + Photosystem II PsbY + Regulatory factor, effector binding domain + Fibrogen-binding domain 1 + Protein of unknown function DUF408 + GSKIP domain + WTAP/Mum2 family + TAP42-like protein + Zinc finger, DNA-directed DNA polymerase, family B, alpha + Glutamine synthetase type I + Translationally controlled tumour protein + tRNA pseudouridine synthase B family + ATPase, V0 complex, subunit e1/e2 + Haem oxygenase + Retinoblastoma-associated protein, A-box + Domain of unknown function DUF3456 + PAM68-like + WASH1, WAHD domain + XRN-Two Binding Domain, XTBD + C-type cytochrome, methanol metabolism-related + Fyv7/TAP26 + DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site + Surface presentation of antigen (SpoA) + Peptidase M2, peptidyl-dipeptidase A + Retrieval of early ER protein Rer1 + Protein hinderin + Cytochrome b6-f complex Fe-S subunit + Nucleoporin, Nup133/Nup155-like, N-terminal + Alpha/beta hydrolase fold-5 + Uncharacterised protein family HutD/Ves + Transcription regulator HTH, Crp-type, conserved site + Squalene cyclase + DNA-directed RNA polymerase, phage-type + Protein of unknown function DUF1058 + Proteasome assembly chaperone 4 + Coatomer subunit gamma, C-terminal + Cilia- and flagella-associated protein 61, N-terminal domain + Ribosomal protein S10, eukaryotic/archaeal + ATPase, V1 complex, subunit A + ATPase, V1 complex, subunit B + Ribosomal protein L22/L17, eukaryotic/archaeal + Phosphonate metabolism protein PhnI + Autophagy-related protein 3, C-terminal + Conserved oligomeric Golgi complex subunit 5 + WIBG family + Linker histone H1/H5, domain H15 + Protein of unknown function DUF4089 + Glycosyl hydrolase 36, catalytic domain + Ribosomal protein S8e + XPG/Rad2 endonuclease, eukaryotes + Spermidine/spermine synthases + Proliferating cell nuclear antigen, PCNA, C-terminal + Proliferating cell nuclear antigen, PCNA, N-terminal + Chemotaxis receptor methyltransferase CheR, N-terminal + Protein of unknown function DUF3253 + Putative ABC transporter periplasmic binding protein PhnD-like + Sulfite dehydrogenase SoxC + Quinoprotein dehydrogenase-associated SoxYZ-like carrier + Nucleolar 27S pre-rRNA processing, Urb2/Npa2, C-terminal + Protein of unknown function DUF2442 + RNA polymerase sigma factor 54 + FeoB-type guanine nucleotide-binding (G) domain + Chromosomal replication control, initiator DnaA + Ribosomal RNA-processing protein 7 + Condensin complex subunit 1, N-terminal + Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family + Metaxin, glutathione S-transferase domain + Protein of unknown function DUF962 + Domain of unknown function DUF1254 + RNA methyltransferase bin3, C-terminal + Nucleolar GTP-binding protein 1, Rossman-fold domain + Anti-sigma-28 factor, FlgM + Elongation factor P hydroxylase + SinI-like, DNA-binding domain + Protein phosphatase 4 core regulatory subunit R2 + Ataxin-2, C-terminal + NAD-dependent DNA ligase, active site + Peptidase HybD-like domain + RZZ complex, subunit Zw10 + Pre-mRNA-splicing factor Isy1 + Coenzyme PQQ biosynthesis protein A + Phosphate ABC transporter, substrate-binding protein PstS + Hypoxanthine phosphoribosyl transferase + GC-rich sequence DNA-binding factor domain + Dynein family light intermediate chain + 40S ribosomal protein S4, C-terminal domain + Antitoxin ParD + Phosphoenolpyruvate carboxylase, His active site + ABC transporter, substrate-binding protein, PQQ-dependent alcohol dehydrogenase system + Coenzyme PQQ synthesis D, bacteria + THO complex subunit 7/Mft1 + SRP-independent targeting protein 2/TMEM208 + Pre-mRNA splicing factor component Cdc5p/Cef1 + O-phosphoseryl-tRNA(Sec) selenium transferase + Dihydrofolate reductase conserved site + Asp/Glu racemase, active site 1 + Dynein attachment factor, N-terminal + Protein of unknown function DUF2127 + Ribosomal protein L37e + FANCI solenoid 4 domain + Glycosyl transferase family 54 + Opioid growth factor receptor (OGFr) conserved domain + CRISPR-associated protein, Cas5 + TAFII55 protein, conserved region + Uncharacterised protein family UPF0145/C2CD5 + Sortilin, C-terminal + SF3A3 domain + Chromophore lyase CpcT/CpeT + Cofactor of BRCA1 + Domain of unknown function DUF4460 + Ribosomal protein S2, eukaryotic/archaeal + Ribosomal protein S3, eukaryotic/archaeal + Exopolysaccharide synthesis protein + Photosystem I PsaJ, reaction centre subunit IX + Zinc finger, CHCC-type + Phosphoribosylaminoimidazole carboxylase, ATPase subunit + Cytochrome b6/f complex, subunit IV + FAM178 family + Nitrous-oxide reductase + Protein of unknown function DUF2889 + Arginase + Macrophage migration inhibitory factor + Conserved hypothetical protein CHP02391 + Bacterial RecJ exonuclease + Domain of unknown function DUF2241 + Domain of unknown function DUF2236 + Protein of unknown function DUF1853 + Protein of unknown function DUF1850 + Nitrile hydratase beta subunit domain + Stomatin family + Ribosomal protein L40e + Uncharacterised conserved protein UCP014543 + Pre-mRNA cleavage complex subunit Clp1 + Sugar transport protein + Uncharacterised protein family, zinc metallopeptidase putative + Protein of unknown function DUF485 + Protein of unknown function DUF481 + Domain of unknown function DUF418 + Nrap protein domain 1 + Urocanase, Rossmann-like domain + SGS domain + UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD + Type II secretion system, protein M + Nucleoporin interacting component Nup93/Nic96 + Zinc finger, C2HC5-type + Nitrogen permease regulator 2 + Protein of unknown function DUF4602 + DET1- and DDB1-associated protein 1, N-terminal + Ribosomal protein S21, conserved site + Short chain fatty acid transporter AtoE + Lipocalin, bacterial + DNA replication factor Cdt1, C-terminal + Transthyretin, conserved site + Transthyretin, thyroxine binding site + Recombinase zinc beta ribbon domain + RNA (C5-cytosine) methyltransferase, NOP2 + DNA polymerase III, subunit gamma/ tau, C-terminal + Minichromosome loss protein Mcl1, middle region + Protein of unknown function DUF810 + Protein of unknown function DUF2497 + RNA polymerase, Rpb8 + Gingipain + Periplasmic binding protein/LacI sugar binding domain + RNA polymerase III subunit RPC82-related, helix-turn-helix + ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR + Actin-related protein 2/3 complex subunit 2 + Histone deacetylase interacting domain + Precorrin-6x reductase + Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase + Ciliary BBSome complex subunit 2, C-terminal domain + DNA-directed RNA polymerase III subunit RPC4 + Adenylate cyclase-associated CAP, N-terminal + Creatininase-like domain + Prokaryotic transglycosylase, active site + Las1-like + RNAse P, Rpr2/Rpp21 subunit + Ribosome biogenesis protein, C-terminal + Minor spike protein + 26S proteasome complex ubiquitin receptor, subunit Rpn13 + SH2 domain + Bacterial general secretion pathway protein G-type pilin + FACT complex subunit POB3-like, N-terminal PH domain + Zincin-like metallopeptidase + Domain of unknown function DUF1017 + Coiled-coil domain-containing protein 124 + CASTOR/POLLUX/SYM8 ion channels + Dynein assembly factor 3, C-terminal domain + Quinohemoprotein amine dehydrogenase, gamma subunit maturation protein + Quinohemoprotein amine dehydrogenase, alpha subunit + Protein of unknown function DUF2985 + Prefoldin alpha subunit, archaea-type + TAFII28-like protein + Flagellar motor switch protein FliG, C-terminal + Histamine H3 receptor + GTP cyclohydrolase 1 type 2/Nif3 + Ubiquitin/SUMO-activating enzyme ubiquitin-like domain + Ribosomal protein L29e + Ribosomal protein L37ae + Ribosomal protein L38e + Cystathionine beta-synthase + Peroxide stress protein YaaA + DEAD box helicase DbpA/CsdA, RNA-binding domain + E2F transcription factor, CC-MB domain + 40S ribosomal protein S11, N-terminal + CCR4-NOT transcription complex subunit 1, TTP binding domain + RAWUL domain + Ubiquitin-like modifier-activating enzyme Atg7, N-terminal + CCR4-NOT transcription complex subunit 1, HEAT repeat + Domain of unknown function DUF4010 + Nitrous oxide reductase accessory protein NosL + Chitin-binding, type 1 + Glycoside hydrolase family 10 domain + Zinc finger, ZPR1-type + Domain of unknown function DUF2329 + Allantoicase domain + Cysteinyl-tRNA synthetase, class Ia, DALR + Plectin/S10, N-terminal + Uncharacterised protein family UPF0565 + Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase + Peptidase S49, protease IV + 4-aminobutyrate aminotransferase, bacterial + Uncharacterised protein family UPF0324, bacteria + Autophagy-related protein 22-like + Rad21/Rec8-like protein, C-terminal, eukaryotic + Pre-rRNA-processing protein IPI1/Testis-expressed sequence 10 protein + PI31 proteasome regulator, N-terminal + Protein of unknown function DUF2948 + Domain of unknown function DUF2428, death-receptor-like + Telomere length regulation protein, conserved domain + Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal + 8-oxoguanine DNA glycosylase, N-terminal + GPI inositol-deacylase PGAP1-like + DNA/RNA-binding protein Kin17, conserved domain + Protein of unknown function DUF866, eukaryotic + Domain of unknown function DUF427 + Septum formation inhibitor MinC, C-terminal + Microviridae F protein + Nin one binding (NOB1) Zn-ribbon-like + Cathepsin C exclusion + Protein phosphatase inhibitor + tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 + Squalene cyclase, N-terminal + Squalene cyclase, C-terminal + Cupin domain of unknown function DUF985 + Ribosomal protein L21e, conserved site + Annexin repeat, conserved site + DNA helicase + ResB-like domain + Ribosomal protein L13e, conserved site + 5'-Nucleotidase, conserved site + Secretion protein HlyD, conserved site + Dipeptidylpeptidase IV, N-terminal domain + WxcM-like, C-terminal + Intraflagellar transport protein 20 + Nitrous oxide reductase family maturation protein NosD + Circularly permuted ATP-grasp type 2 + Protein of unknown function DUF3429 + Deoxyguanosinetriphosphate triphosphohydrolase, central domain + Protein FAM135 + 4-hydroxybenzoyl-CoA thioesterase, active site + Protein of unknown function DUF2870 + G10 protein + Doubled CXXCH motif + POPLD + PRO8NT domain + PetM of cytochrome b6/f complex subunit 7 + Sulphur oxidation, SoxY + Ribosomal protein L15e + Checkpoint protein Hus1/Mec3 + LemA + SpoVT-AbrB domain + o-Succinylbenzoate synthase, MenC type 2 + Uncharacterised peroxidase-related + Ras-like guanine nucleotide exchange factor, N-terminal + Flavin-dependent halogenase + Adenine nucleotide translocator 1 + Aliphatic acid kinase, short-chain, conserved site + U6 snRNA phosphodiesterase Usb1 + Association with the SNF1 complex (ASC) domain + Ku, C-terminal + Domain of unknown function DUF4524 + SCL-interrupting locus protein + Symplekin/Pta1, N-terminal + Zinc finger domain-containing protein 24, zinc-binding domain + Protein of unknown function DUF1345 + Spt4/RpoE2 zinc finger + 3-isopropylmalate dehydratase, large subunit + 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase + Isocitrate dehydrogenase NADP-dependent, monomeric + Translation initiation factor 2, gamma subunit, C-terminal + Lytic transglycosylase MltA, domain B + Phosphomannomutase + Ribosomal biogenesis, methyltransferase, EMG1/NEP1 + Protein of unknown function DUF2306, membrane + Uncharacterised protein family Ycf55 + ATP synthase, F0 complex, subunit B/MI25 + Centromere protein Mis12 + FMN reductase, MsuE-like + Transcription factor TFIIE alpha subunit, C-terminal + Chromosome segregation in meiosis protein 3 + Signal recognition particle receptor, beta subunit + Domain of unknown function DUF2012 + Ribosome biogenesis protein Nop16 + BrnA antitoxin of type II toxin-antitoxin system + Low temperature viability protein + TIP41-like protein + Cytochrome b6/f complex, subunit 5 + Thaumatin + Ribosomal protein S21e + Flagellar assembly regulator FliX, class II + Glycoside hydrolase family 9, His active site + Flagellar biosynthesis protein FlhA + DNA polymerase 3, epsilon subunit + Sulphate adenylyltransferase, small subunit + Glycogen/starch/alpha-glucan phosphorylase + Protein of unknown function DUF963 + Cu(I)-responsive transcriptional regulator + RNA polymerase Rpc34 + MOFRL domain + Glycoside hydrolase, family 37, conserved site + Stomatal closure-related actin-binding protein, fused Ig-PH domain + AMP-dependent ligase, C-terminal + RPA-interacting protein, C-terminal domain + Menaquinone biosynthesis protein MenD, middle domain + Domain of unknown function DUF2268 + RNA polymerase Rpb1, domain 6 + U3 small nucleolar RNA-associated protein 15, C-terminal + TfoX, N-terminal + L-seryl-tRNA selenium transferase N-terminal domain + RNA polymerase Rpb1, domain 7 + RNA recognition motif, spliceosomal PrP8 + Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding + Serine dehydratase beta chain + Uncharacterised protein family UPF0114 + ATPase, V1 complex, subunit F + Chromatin target of PRMT1 protein, C-terminal + SoxAX cytochrome complex subunit A + Nucleoporin Nup54, alpha-helical domain + Motility protein B, N-terminal domain + Histone deacetylase complex subunit SAP30, Sin3 binding domain + Mediator complex, subunit Med25, von Willebrand factor type A + Transcription factor TFIIB, cyclin-like domain + Protein of unknown function DUF3054 + TAF6, C-terminal HEAT repeat domain + Protein of unknown function DUF4558 + DNA topoisomerase I, N-terminal + Muconate/chloromuconate cycloisomerase + NfeD-like, C-terminal domain + Aspartate dehydrogenase + 3-dehydroquinate synthase + Ribonuclease H2, subunit C + Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase + RNA polymerase II associated factor Paf1 + Autophagy-related protein 3, N-terminal + SHS2 domain inserted in FtsA + Uncharacterised conserved protein UCP01500 + Ribosomal protein S30 + Pex, N-terminal + JAB domain, prokaryotic + FAM91, C-terminal domain + ATPsynthase alpha/beta subunit, N-terminal extension + Cytochrome c, class II + Cytochrome f + Spermidine/putrescine ABC transporter, ATP-binding subunit + Glycine betaine transport ATP-binding subunit + Ribosomal protein L39e domain + Ribosomal protein L31e domain + Replication protein C + Xanthine phosphoribosyltransferase + Deoxyribonuclease II + Glutamyl-tRNA(Gln) amidotransferase A subunit + Nucleoside-triphosphatase, THEP1 type + ER membrane protein complex subunit 8/9 + Nitrogen permease regulator 3 + Nucleotidyltransferase, predicted + 5-bromo-4-chloroindolyl phosphate hydrolysis protein + B-box-type zinc finger + Nitrogenase component 1, conserved site + Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO + Protein of unknown function DUF2997 + Protein of unknown function DUF2993 + Glutamate 5-kinase, conserved site + Sensitivity To Red Light Reduced-like, SRR1 + Phenol hydroxylase, C-terminal dimerisation domain + Type II secretion system protein G + Ribonuclease H2, subunit B + Pilus biogenesis CpaD-related + Photosystem I PsaF, reaction centre subunit III + FHIPEP conserved site + Domain of unknown function DUF4394 + Domain of unknown function DUF4396 + FMN-binding + Phosphonate ABC transporter, substrate-binding protein + Pex19 protein + SprT-like, zinc ribbon domain + PRMT5, oligomerisation domain + Glutathione reductase, eukaryote/bacterial + Potassium-transporting ATPase C chain + GTP cyclohydrolase FolE2/MptA + ATP-grasp fold, DUF201-type + Glutamyl-tRNA reductase, conserved site + Pre-mRNA polyadenylation factor Fip1 + CHASE domain + 6-phosphogluconate dehydrogenase + AMMECR1, N-terminal + Methylmalonic aciduria and homocystinuria type C family + Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase, eukaryotic + Dihydrodipicolinate reductase, plant-type + Vasohibin + General secretion pathway protein F + Phage major tail protein TP901-1 + Iron sulphur-containing domain, CDGSH-type + DNA replication licensing factor Mcm7 + Ribonuclease P/MRP protein subunit + Na+/H+ antiporter subunit E + DNA primase, small subunit + Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain + Alpha-2-macroglobulin, thiol-ester bond-forming + Translocon Sec61/SecY, plug domain + Cellulose synthase + Ribosome biogenesis factor NIP7-like + Non-homologous end joining protein Ku, prokaryotic type + Ferredoxin thioredoxin reductase, alpha chain + mRNA triphosphatase Cet1-like + Chorismate mutase, AroQ class, eukaryotic type + Ferredoxin thioredoxin reductase catalytic beta subunit + Serine/threonine-protein kinase, C-terminal + DNA (cytosine-5)-methyltransferase 1, replication foci domain + Domain of unknown function DUF3535 + PucR C-terminal helix-turn-helix domain + Protein of unknown function DUF4169 + Serine proteases, trypsin domain + Galactose-3-O-sulfotransferase + Magnesium chelatase, subunit H, N-terminal + Ribonuclease P/MRP, subunit POP1 + SdiA-regulated + Entericidin A/B + Protein of unknown function DUF3689 + POTRA domain, FtsQ-type + Protein of unknown function DUF3082 + Tubulin-specific chaperone D, C-terminal + Alkyl hydroperoxide reductase subunit F + Nickel/cobalt homeostasis protein RcnB + Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 + ERp29, N-terminal + Formiminotransferase, N-terminal subdomain + L-fucokinase + mRNA splicing factor Cwf21 domain + Protein of unknown function DUF1045 + Dolichol-phosphate mannosyltransferase subunit 3 + Domain of unknown function DUF1713 + Protein of unknown function DUF1712, fungi + CRISPR pre-crRNA endoribonuclease Cas5d + 2-phospho-L-lactate guanylyltransferase, CofC + Piezo non-specific cation channel, R-Ras-binding domain + Fibrillarin + Neutral/alkaline non-lysosomal ceramidase, C-terminal + Alpha-L-fucosidase, C-terminal + RIH (RyR and IP3R Homology) domain + TB domain + Type II secretion system GspD + Pyrimidine-nucleoside phosphorylase, conserved site + Hydroxyisourate hydrolase + Xanthine dehydrogenase, molybdopterin binding subunit + Putative sugar-binding, N-terminal domain + Ribosome biogenesis protein Nop53/GLTSCR2 + DNA polymerase III, subunit gamma/ tau + Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site + Mad1/Cdc20-bound-Mad2 binding protein + Quinohemoprotein amine dehydrogenase, gamma subunit, structural domain + Photosystem II PsbX + Outer membrane protein, OmpW + Uncharacterised protein family FAM98 + Voltage-dependent anion channel + Cytochrome c oxidase assembly protein PET191 + PRTase ComF-like + SANT associated + Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal + Dyskerin-like + Peptidase M54, archaemetzincin + Nitrite reductase [NAD(P)H] small subunit, NirD + M-phase phosphoprotein 6 + tRNA(Met) cytidine acetyltransferase TmcA, N-terminal + Nucleoporin protein Ndc1-Nup + Ribosomal protein S27e + DEP domain + C8orf37 protein + Uncharacterised conserved protein UCP014753 + Type II secretion system protein C, N-terminal + Rhamnosyl O-methyltransferase/Cephalosporin hydroxylase + Acyclic terpene utilisation + Pseudouridine synthase TruD, conserved site + SapC + Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal + Formate dehydrogenase, alpha subunit + Proliferating cell nuclear antigen, PCNA + Lariat debranching enzyme, C-terminal + S-adenosylmethionine decarboxylase family, prokaryotic + Bacterial export protein family 3 + MAGE homology domain + Chs5p-Arf1p binding + Snapin/Pallidin/Snn1 + Nucleolar protein 12 + Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB + Integral membrane protein SYS1-related + Oxysterol-binding protein, conserved site + Tetraspanin/Peripherin + Deoxyhypusine synthase + Enhancer of polycomb-like, N-terminal + Signal recognition particle, SRP19 subunit + Tetratricopeptide, SHNi-TPR domain + PPC domain + Cytochrome C oxidase subunit IV, prokaryotes + Transaldolase type 3B/Fructose-6-phosphate aldolase + Dna2/Cas4, domain of unknown function DUF83 + Protein of unknown function DUF2783 + ChrR-like cupin domain + Nuclear condensin complex subunit 3, C-terminal domain + Sensor protein KdpD, transmembrane domain + Protein of unknown function DUF1287 + PTHB1, N-terminal domain + NIPSNAP + Tubulin binding cofactor A + Protein of unknown function DUF3108 + Zinc finger, Mcm10/DnaG-type + Sorting nexin Vps5-like, C-terminal + Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ + CCR4-Not complex, Not1 subunit, domain of unknown function DUF3819 + Ribonuclease P + Histidine biosynthesis HisG, C-terminal + FAD-binding 9, siderophore-interacting + Type I secretion outer membrane protein, TolC + Polyhydroxyalkanoate synthesis repressor PhaR + Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase + Photosystem II PsbV, cytochrome c-550 precursor + Sof1-like protein + Peptidase, C-terminal, archaeal/bacterial + Fatty acid synthase + Gas2-related domain + Coactivator CBP, KIX domain + Benzoate 1,2-dioxygenase, small subunit + PRMT5, TIM barrel domain + G patch domain-containing protein, N-terminal + Brf1, TBP-binding domain + Formiminotransferase, C-terminal subdomain + Polymorphic outer membrane protein repeat + Ribosomal RNA-processing protein 14, N-terminal + Gingipain propeptide + Protein of unknown function DUF4504 + YmcC-like domain + CRISPR-associated protein Cas1, DVULG subtype + TPX2, C-terminal + PRP1 splicing factor, N-terminal + N-acetylmuramoyl-L-alanine amidase, catalytic domain + NAD kinase + Protein of unknown function DUF1150 + Centromere protein X + Domain of unknown function DUF2007 + Ribosomal protein L10, eubacterial, conserved site + Ribosomal protein L23/L25, N-terminal + Chaperone protein Skp + BRCA2, OB1 + Quinohemoprotein amine dehydrogenase, alpha subunit domain IV + Quinohemoprotein amine dehydrogenase, alpha subunit, haem binding domain + Domain of unknown function DUF3772 + Demeter, RRM-fold domain + CEP76, C2 domain + Mannose-6-phosphate receptor + CC2D2A, N-terminal, C2 domain + Transcription termination and cleavage factor, C-terminal domain + Tellurite resistance methyltransferase TehB-like domain + T-complex protein 1, zeta subunit + T-complex protein 1, theta subunit + T-complex protein 1, eta subunit + Molybdenum cofactor biosynthesis protein B, proteobacteria + DNA-binding, RecF + Cysteine-rich domain + SKI-interacting protein SKIP, SNW domain + RPEL repeat + Phosphoinositide phospholipase C family + Ribosomal protein L10e + PDK1-type, PH domain + Type II secretion system conserved site + FAM183 family + Arylamine N-acetyltransferase + Selenoprotein SelK/SelG + C-protein + Ubiquitin-fold modifier-conjugating enzyme 1 + Cytochrome oxidase assembly protein 1 + DNA replication factor Dna2, N-terminal + Protein of unknown function DUF1479 + Saposin-like type B, region 1 + Uncharacterised conserved protein UCP037205 + TTHA1013/TTHA0281-like + V-type ATPase subunit c domain + DAMP1, SANT/Myb-like domain + CHASE2 + PHB accumulation regulatory + Chlorhexidine efflux transporter + MASE1 + SS18 family + 2-keto-3-deoxy-galactonokinase + Pre-SET domain + Origin recognition complex, subunit 5 + Protein of unknown function DUF883, ElaB + Histone-like protein H-NS, C-terminal domain + Transcription elongation factor Spt6, helix-hairpin-helix motif + Origin recognition complex subunit 4, C-terminal + Asparaginase/glutaminase, active site 1 + Cell division protein FtsA + Cytochrome c oxidase cbb3 type, accessory protein FixG + Protein of unknown function DUF1475 + Glutaredoxin, eukaryotic/virial + Tapt1 family + Toxin CcdB + SNARE-complex protein Syntaxin-18, N-terminal + Retinoblastoma-associated protein, B-box + Repressor of yield of DENV protein + Protein of unknown function DUF2585 + TniQ + Protein of unknown function DUF1116 + Generative cell specific-1, HAP2-GCS1 + Ciliary BBSome complex subunit 2, middle region + Domain of unknown function DUF1971 + Acyl-CoA dehydrogenase, C-termina, bacterial type + E3 UFM1-protein ligase 1 + Protein of unknown function DUF2043 + Protein of unknown function DUF2052, coiled-coil + Domain of unknown function DUF2040 + Domain of unknown function DUF4159 + Pyridoxamine 5-phosphate oxidase, FMN-dependent + Pectate lyase superfamily protein + SAP30-binding protein + Protein KTI12/L-seryl-tRNA(Sec) kinase + Oligopeptidase F, N-terminal domain + 2-phospho-L-lactate transferase + 116kDa U5 small nuclear ribonucleoprotein component, N-terminal + Vacuolar protein sorting 55 + Rad9/Ddc1 + Transcription factor TFIIE beta subunit, DNA-binding domain + Ferrous iron transport protein B, C-terminal + High-CO2 inducible periplasmic + Nucleoside transporter/FeoB GTPase, Gate domain + Protein of unknown function DUF1754, eukaryotic + Vacuolar import/degradation, Vid27-related + Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase + Transmembrane protein DUF1751, eukaryotic + Uncharacterised protein family, Ynq1 + Uncharacterised protein family, CD034/YQF4 + Double transmembrane domain + BCNT-C domain + BRCA1-associated 2 + Protein of unknown function DUF502 + Mitochondrial import inner membrane translocase subunit Tim21 + Transposase IS204/IS1001/IS1096/IS1165, DDE domain + Antirepressor protein, C-terminal + Ribosome maturation protein SBDS, conserved site + Organic solvent tolerance-like, N-terminal + Cdc6, C-terminal + Aspartate racemase + Peptidase M50, putative membrane-associated zinc metallopeptidase + Nucleoside diphosphate pyrophosphatase + Protein of unknown function DUF2933 + Biogenesis of lysosome-related organelles complex-1, subunit 2 + Protein of unknown function UPF0568 + Domain of unknown function DUF2272 + IGR protein motif + DNA/RNA non-specific endonuclease + CDC48, domain 2 + Conserved hypothetical protein CHP03643 + Cytochrome b-c1 complex subunit 8 + Chaperonin ClpB + Clathrin adaptor complex, small chain + Ribosomal protein S7e + Zinc finger, SWIM-type + Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal + RINT-1/Tip20 + TATA-box binding protein, conserved site + Glyceraldehyde-3-phosphate dehydrogenase, type II + Cytochrome b245, heavy chain + Cytochrome c oxidase copper chaperone + Ribosomal protein/NADH dehydrogenase domain + Ribosomal protein L49/IMG2 + Magnesium-protoporphyrin IX methyltransferase + Peptidase S8 propeptide/proteinase inhibitor I9 + Conjugal transfer, TrbG/VirB9/CagX + Photosystem II CP47 reaction centre protein + Ribonuclease D + Vps16, N-terminal + DNA primase, DnaG + tRNase Z endonuclease + Flagellum biosynthesis repressor FlbT + Laminin EGF domain + Ran GTPase + Adipokinetic hormone, conserved site + Ribonuclease P/MRP, subunit p29 + AMMECR1 domain + Bardet-Biedl syndrome 1, N-terminal + Deaminase, LmjF36.5940-like + Romo1/Mgr2 + Uncharacterised protein family UPF0573/UPF0605 + Fanconi anaemia protein FANCD2 + Exostosin , C-terminal + NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 + Protein of unknown function DUF2160, transmembrane + Protein of unknown function DUF697 + Potassium channel, calcium-activated, SK + Protein phosphatase 1 regulatory subunit 36 + Protein of unknown function DUF2855 + Kinesin-associated + Peptide Chain Release Factor eRF1/aRF1, N-terminal + Protein MM3350-like domain + Cobalamin (vitamin B12) biosynthesis CobW + Haemerythrin, metal-binding domain + Holin of 3TMs, for gene-transfer release + Carbohydrate binding module, xylan-binding domain + Dopey, N-terminal + S-adenosyl-L-methionine-dependent methyltransferase, putative + Atg6/Beclin + Autophagy-related protein 9 + GPI transamidase component Gaa1 + Nrap protein, domain 5 + GPI transamidase component PIG-T + Iron dependent repressor, metal binding and dimerisation domain + Type II secretion system protein I domain + Peptidase M61, catalytic domain + Iron hydrogenase, small subunit + PQQ-dependent membrane bound dehydrogenase + Alpha-2-macroglobulin, N-terminal 2 + BOP1, N-terminal domain + Ribosomal protein S4e, central region + mRNA capping enzyme, C-terminal + Ribosomal protein S4e, N-terminal + CASP, C-terminal + Protein of unknown function DUF991 + 5-nucleotidase + RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 + Choloylglycine hydrolase/NAAA C-terminal + Biofilm formation YgiB + Putative small multi-drug export + Protein of unknown function DUF1192 + Sodium-dependent phosphate transport protein + Peptidase S11, D-alanyl-D-alanine carboxypeptidase A + DNA topoisomerase I catalytic fragment, domain 2 + Protein of unknown function DUF3617 + SNU66/SART1 family + GUN4-like + Protein of unknown function DUF3727 + Cbb3-type cytochrome oxidase component + Pre-mRNA splicing factor + Domain of unknown function DUF4461 + Citramalate synthase + Glucose-1-phosphate thymidylyltransferase, short form + Phosphate transport system permease protein PstA + Epsilon tubulin + Prolyl-tRNA synthetase, class IIa, bacterial-type + DNA topoisomerase II, eukaryotic-type + TMC + Photosystem II Pbs27 + Helicase-associated putative binding domain + Major facilitator superfamily associated domain + Sister chromatid cohesion C-terminal domain + RNA 3'-terminal phosphate cyclase type 2 + Ribosomal protein S28e + TonB-system energizer ExbB type-1 + S-adenosylmethionine decarboxylase proenzyme + Alpha-L-arabinofuranosidase, C-terminal + Pyrimidine 5-nucleotidase + Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase + Conserved hypothetical protein CHP02001 + Manganese catalase, domain 2 + Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal + RNA polymerase II-binding domain + Type IV secretion system protein VirB11 + Timeless protein + Double-strand break repair protein AddB + DNA helicase, AddA type + D-glutamate cyclase + Transcription initiation factor TFIID, subunit 12 + FY-rich, N-terminal + FY-rich, C-terminal + Manganese catalase + Transmembrane protein family 132, middle domain + Ribosomal protein L5 eukaryotic/L18 archaeal + Sedoheptulose-1,7-bisphosphatase + Amidase, carbamoylase-type + TupA-like ATPgrasp protein + Aspartate kinase, monofunctional class + Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG + DEXH box helicase, DNA ligase-associated + Domain of unknown function DUF2087 + Phenylalanine/histidine ammonia-lyases, active site + Protein of unknown function DUF2794 + Translation initiation factor 3 complex subunit L + Retinoic acid induced 16-like protein + Proteinase inhibitor I46, leech metallocarboxypeptidase inhibitor + Cellulose synthase operon C, C-terminal + B-cell receptor-associated protein 29/31 + Sister chromatid cohesion protein Dcc1 + Exosortase EpsH-related + Signal recognition particle receptor, alpha subunit, N-terminal + Cell shape-determining protein MreD + Cytochrome c oxidase, subunit VIa + Glycine dehydrogenase (decarboxylating) + CCR4-Not complex component, Not1, C-terminal + Cdc23 + Up-frameshift suppressor 2 + Ssl1-like + Cell division control protein 73, C-terminal + Branched-chain amino acid transport, permease + Glycoside hydrolase 35, catalytic domain + Domain of unknown function DUF4942 + Cytochrome c-type biogenesis protein CcsA + RNA polymerase I specific transcription initiation factor RRN3 + Splicing factor RBM39, linker + Uncharacterised protein family 14.7kDa + Neuralized homology repeat (NHR) domain + mRNA-decapping enzyme subunit 1 + KEN domain + Cytochrome c-type biogenesis protein CcmB, bacteria + Peptidase C54 + Peptidase M74, penicillin-insensitive murein endopeptidase + Toluene tolerance Ttg2/phospholipid-binding protein MlaC + Bacterial TniB + T-complex 11 + Uncharacterised conserved protein UCP028101 + Metal-independent alpha-mannosidase + MiaB-like tRNA modifying enzyme, archaeal-type + Transcription regulator YbiH, C-terminal + Inositol-tetrakisphosphate 1-kinase + Uncharacterised conserved protein UCP025560 + Imidazolonepropionase + Agmatinase-related + Chromatin assembly factor 1 subunit A + snRNA-activating protein complex, subunit 3 + Asparagine-tRNA ligase + Aspartate-tRNA synthetase, type 2 + Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic + Elongation factor P--(R)-beta-lysine ligase + 3-deoxy-D-manno-octulosonate cytidylyltransferase + Signal recognition particle subunit SRP68 + Peptidase S8A, tripeptidyl peptidase II + Protein of unknown function DUF3752 + 2-oxoisovalerate dehydrogenase, E1 alpha subunit, N-terminal domain + NAD(P) transhydrogenase, alpha subunit + Fanconi Anaemia group E protein, C-terminal + Transcription initiation factor IIA, gamma subunit, C-terminal + Cdk-activating kinase assembly factor MAT1, centre + Uncharacterised protein family UPF0210 + Carboxyltransferase domain, subdomain C and D + Phosducin, thioredoxin-like domain + Integration host factor, beta subunit + ABC transporter, urea permease protein UrtB, bacterial-type + Atrophin-1 + SsrA-binding protein, conserved site + Poly(R)-hydroxyalkanoic acid synthase, class I + AAA ATPase, CDC48 family + Protein of unknown function DUF3611 + (5-formylfuran-3-yl)methyl phosphate synthase + Restriction endonuclease type IV, Mrr + Actin-related protein 2/3 complex subunit 5 + Peroxin-3 + Peroxisome membrane anchor protein Pex14p, N-terminal + Pinin/SDK/MemA protein + WASH complex subunit 7, N-terminal + Protein of unknown function DUF1457 + Eukaryotic translation initiation factor 3 subunit D + Putative glycogen debranching enzyme, N-terminal + Endo-1,3(4)-beta-glucanase + Glycoside hydrolase, family 85 + MOFRL-associated domain + Arf3-interacting protein 1, N-terminal domain + Protein of unknown function DUF1636 + Transcription regulator Myc, N-terminal + Uncharacterised protein family Ycf33 + MnmC-like methyltransferase + PBS lyase HEAT-like repeat + Aspartic peptidase, DDI1-type + Cytochrome c oxidase caa3-type, assembly factor CtaG-related + CCR4-Not complex component, Not N-terminal domain + Actin-related protein 2/3 complex subunit 3 + 4Fe-4S domain + Na(+)/H(+) antiporter subunit F-like + Lamin Tail Domain + Photosystem II cytochrome b559, alpha subunit, lumenal region + Replication origin-binding protein + Pre-mRNA-splicing factor 3 + Yos1-like + Protein of unknown function DUF1764, eukaryotic + Domain of unknown function DUF4392 + Nrap protein, domain 3 + Anti-sigma-28 factor FlgM, C-terminal + DMSO/Nitrate reductase chaperone + DNA primase, small subunit, eukaryotic/archaeal + Phosphate-starvation-induced PsiE-like + Addiction module antidote protein, HI1420 + Addiction module killer protein, predicted + Bacteriophage regulatory protein, Rha family + Heme D1 biosynthesis, radical SAM protein NirJ + Translation initiation factor 2, alpha subunit + Eukaryotic translation initiation factor 3-like domain + Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal + MerC mercury resistance protein + Suppressor of forked + Pyruvate/ketoisovalerate oxidoreductase, catalytic domain + Proline-specific peptidase + Succinyl-diaminopimelate desuccinylase, proteobacteria + Anthranilate phosphoribosyl transferase + U1 small nuclear ribonucleoprotein of 70kDa N-terminal + Multicopper oxidase, type 1 + Ribosomal RNA-processing protein 15 + Protein of unknown function DUF1656 + Protein of unknown function DUF1236 + Heat shock factor binding 1 + Protein of unknown function DUF3337 + Protein of unknown function DUF3342 + ATP-grasp fold, RimK-type + LPS export ABC transporter, ATP-binding protein LptB + LPS export ABC transporter permease LptF + Peptide chain release factor 3 + Acetyl-CoA carboxylase, biotin carboxylase + Prp18 + TMEM33/Pom33 family + Glucosamine-6-phosphate isomerase + Ribosomal protein S12e + Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic + ATPase, type I secretion system + Magnesium-protoporphyrin IX methyltransferase, C-terminal + Malate dehydrogenase, type 2 + LOR/SDH bifunctional enzyme, conserved domain + Poly(A) polymerase, RNA-binding domain + O-antigen ligase-related + Mediator complex, subunit Med6 + Cystathionine beta-lyase, bacterial + Cystathionine beta-lyase, eukaryotic + SF3A2 domain + FixG, C-terminal immunoglobulin-like domain + Vacuole morphology and inheritance protein 14, Fab1-binding region + U3 small nucleolar RNA-associated protein 6 + Mediator complex, subunit Med14 + RNA 3'-terminal phosphate cyclase-like, conserved site + LEM/LEM-like domain + AraC-type transcription regulator, ligand-binding domain + Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site + Bacterioferritin + CG-1 DNA-binding domain + Kinetochore protein Ndc80 + LydA-like holin + Riboflavin biosynthesis protein RibD + Centrosomal protein of 19kDa + Periplasmic protein thiol:disulphide oxidoreductase DsbE + Protein of unknown function DUF4498 + Tricorn protease, PDZ domain + Nuclear protein 96 + Splicing factor SF3a60 binding domain + Ribosomal protein S24/S35, mitochondrial, conserved domain + Fanconi anemia complex, subunit FancL, WD-repeat containing domain + K+ transporting P-type ATPase, F subunit + GSCFA + Domain of unknown function DUF4131 + Carbamoyltransferase + Gluconate transporter + mRNA interferase PemK-like + Quinolinate synthetase A + Peptidase C15, pyroglutamyl peptidase I-like + Protein of unknown function DUF535 + Stringent starvation protein B + Malonyl-CoA decarboxylase, C-terminal + Cobaltochelatase subunit CobS + Ribosomal protein L39e + Domain of unknown function DUF4982 + Deoxycytidine triphosphate deaminase, bacterial + Transcription factor IIA, beta-barrel + HemY, N-terminal + SepSecS/SepCysS family + S-adenosylmethionine decarboxylase + Bacterial glucose/galactose transporter + D-cysteine desulfhydrase + Phenylalanine-4-hydroxylase, monomeric form + Glycosyl hydrolase family 99 + Fructose-bisphosphate aldolase class-I active site + Diphosphomevalonate decarboxylase + Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site + Uncharacterised protein family Ycf35 + RNA polymerase I associated factor, A49-like + Transmembrane protein 43 family + Glutamate-cysteine ligase catalytic subunit + Acetamidase/Formamidase + Pca transcription factor PcaQ + Zinc finger, C4 DksA/TraR-type + 4-carboxymuconolactone decarboxylase + Isochorismate synthase + Copper amine oxidase + DNA-directed RNA polymerase, subunit N/Rpb10 + Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term + Nucleolar pre-ribosomal-associated protein 1, N-terminal + Gemini of Cajal bodies-associated protein 8 + Condensin-2 complex subunit G2 + Pyridoxamine 5'-phosphate oxidase-related + TFIIH subunit Tfb4/p34 + Class I myosin tail homology domain + Conjugal transfer TrbC/type IV secretion VirB2 + Protein of unknown function UPF0178 + VPS13, repeated coiled region + Nrap protein, domain 2 + RAI1-like + Mon2, C-terminal + Oligosaccharide biosynthesis protein Alg14-like + SbsA, Ig-like domain + Vacuolar membrane-associated protein Iml1 + Chromosome segregation protein Spc25 + Chromosomal replication control, initiator DnaA-like + Gamma-glutamyl phosphate reductase GPR, conserved site + Ribosomal protein S16, conserved site + Protein of unknown function DUF2271 + Tyrosinase copper-binding domain + Catalase haem-binding site + Photosystem II cytochrome b559, alpha subunit + Methionyl-tRNA formyltransferase + Tab2-like + DNA polymerase III, delta subunit + Protein translocase subunit SecD + Chaperonin GroES, conserved site + KorB, C-terminal + rRNA biogenesis protein RRP36 + RNA polymerase, Rpb5, N-terminal + RNA polymerase II, Rpb4 + Gamma-secretase subunit Aph-1 + Yif1 family + Cgr1-like + Protein of unknown function DUF4639 + N-acetyl-gamma-glutamyl-phosphate reductase, active site + Clathrin, heavy chain, propeller repeat + Ribosomal protein S23/S29, mitochondrial + DNA primase/polymerase, bifunctional, N-terminal + Histone PARylation factor 1 + PDZ-binding protein, CRIPT + Nuclear fragile X mental retardation-interacting protein 1, conserved domain + Cactin, central domain + Nuclear protein DGCR14 + Mediator complex, subunit Med10 + Mini-chromosome maintenance complex-binding protein + 3-dehydroquinate dehydratase type I + Ras guanine-nucleotide exchange factors catalytic domain + Malic oxidoreductase + RNA-binding, CRM domain + Retinoblastoma-associated protein, N-terminal + Ribonuclease, PIN domain + FANCI helical domain 2 + KHA domain + U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 + TFIIH subunit Ssl1/p44 + Free Met sulfoxide reductase conserved site + Virulence-associated E + CST complex subunit Ten1, animal and plant type + FACT complex subunit Spt16, N-terminal lobe domain + Ribosomal protein L31e + Uncharacterised protein family Ycf34 + Ribosome maturation protein Sdo1/SBDS + Cancer susceptibility candidate 1, N-terminal + HAD-superfamily phosphatase, YqeG-like + Galactonolactone dehydrogenase + Orotidine 5'-phosphate decarboxylase, type 2 + ATP11 + GPI transamidase subunit PIG-U + Domain of unknown function DUF302 + LsmAD domain + Cas1p 10 TM acyl transferase domain + Transcription elongation factor, GreA/GreB, conserved site + Glycosyltransferase, ALG3 + Glutaredoxin-like + Dicarboxylate transport + Vacuolar protein sorting protein 11, C-terminal + Domain of unknown function DUF2235 + Protein of unknown function DUF3604 + GspF/PilC family + BON domain + CHORD domain + DNA-directed RNA polymerase, 30-40kDa subunit, conserved site + Nuclear-interacting partner of ALK/Rsm1-like + Eukaryotic translation initiation factor 3 subunit J + Helicase XPB/Ssl2, N-terminal domain + Rab3-GAP regulatory subunit, N-terminal + Methanolan biosynthesis EpsI + Cyanovirin-N + Nucleoporin Nup85-like + Nucleolar complex-associated protein 3, N-terminal + Orotate phosphoribosyltransferase, bacterial + Acetyl-S-ACP:malonate ACP transferase + UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type + ATPase, V1 complex, subunit F, eukaryotic + AVL9/DENND6 domain + Aromatic amino acid hydroxylase, iron/copper binding site + Domain of unknown function DUF4520 + WASH complex subunit 7, C-terminal + WASH complex subunit 7, central domain + Domain of unknown function DUF5001 + Fis1, C-terminal tetratricopeptide repeat + DNA polymerase epsilon, catalytic subunit A, C-terminal + General secretion pathway, GspH + WHG domain + Periplasmic binding protein + Transmembrane protein 231 + WASH complex subunit 3 + PRONE domain + Vitelline membrane outer layer protein I (VOMI) + Cryptochrome DASH + DNA photolyase class 2 + Ribonuclease H2, subunit A + DNA/RNA-binding domain, Est1-type + Co-chaperone Hsc20 + Domain of unknown function DUF4126 + Domain of unknown function DUF4115 + Cellular retinaldehyde binding/alpha-tocopherol transport + O-methyltransferase, family 2 + Domain of unknown function DUF4365 + Ribosomal protein L19/L19e, domain 2 + Ribosomal protein L19/L19e, domain 3 + Arsenical pump ATPase, ArsA/GET3 + DNA helicase (DNA repair), Rad3 type + Glucan biosynthesis, periplasmic, MdoG C-terminal + SAGA complex, Sgf11 subunit + SCA7 domain + DNA-directed RNA polymerase I, subunit RPA34.5 + Uncharacterised protein family UPF0220 + RNA-binding motif protein 8 + Lipocalin-like domain + Rare lipoprotein A + Alkylbase DNA glycosidase, conserved site + Peptidase A24A, N-terminal + Domain of unknown function DUF4743 + HicB-like antitoxin of toxin-antitoxin system + MTA/SAH nucleosidase + HAD-superfamily hydrolase, subfamily IIA, CECR5 + Crotonyl-CoA reductase + Bifunctional uridylyltransferase/uridylyl-removing enzyme + Oxidoreductase alpha (molybdopterin) subunit + Peptidase A24A, prepilin type IV, bacterial + Dihydropteroate synthase + Splicing factor 3B subunit 5/RDS3 complex subunit 10 + Mutator MutT + Lipase, GDXG, putative histidine active site + Pyridoxal 5'-phosphate synthase subunit PdxT/SNO + Type III secretion system substrate exporter + Serine/threonine-protein kinase SMG1 + Chemotaxis methyl-accepting receptor + Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain + Protein of unknown function DUF4598 + Tetratricopeptide TPR-3 + RbsD-like domain + Bacteriophage lambda, GpH, tail tape measure, N-terminal + CagE, TrbE, VirB component of type IV transporter system + Aerotolerance regulator, N-terminal + PTP type protein phosphatase + Sortilin, N-terminal + Alcohol ABC transporter, permease protein + Acyl-CoA-binding protein, ACBP, conserved site + GPR domain + Protein of unknown function DUF1749 + DNA polymerase family X, binding site + EcsC protein + Translin, N-terminal + Glycoside hydrolase, family 59 + LicD family + Photosystem I PsaL, reaction centre subunit XI + Putative RNA methyltransferase + Rad1/Rec1/Rad17 + Succinylarginine dihydrolase + Mannose-6-phosphate isomerase, type II, C-terminal + Acetylserotonin O-methyltransferase, dimerisation domain + Coilin, N-terminal domain + RNA polymerase II-associated protein 1, C-terminal + Mediator complex, subunit Med20 + Protein of unknown function DUF898 + Na+-dependent bicarbonate transporter superfamily + Uncharacterised protein family CreA + Protein of unknown function DUF1003 + LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 + Small-subunit processome, Utp14 + Rad4 beta-hairpin domain 2 + Rad4 beta-hairpin domain 1 + Glucosamine-6-phosphate isomerase, conserved site + DNA polymerase 1 + Rad4 beta-hairpin domain 3 + 60S ribosomal protein L4, C-terminal domain + Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain + Anti-proliferative protein + Flagellar motor switch protein FliG, N-terminal domain + Fic/DOC N-terminal + AP-4 complex subunit epsilon-1, C-terminal + Beta-galactosidase, domain 3 + N-acetyltransferase ESCO, acetyl-transferase domain + Ribosomal protein L13, eukaryotic/archaeal + Neurochondrin + Cobalamin biosynthesis CobD/CbiB + Cobalamin-independent methionine synthase MetE, C-terminal/archaeal + Protein of unknown function DUF2373 + RNA polymerase II assembly factor Rtp1, C-terminal + BLOC-1-related complex subunit 8 + Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2 + Telomerase activating protein Est1 + GPI-GlcNAc transferase complex, PIG-H component, conserved domain + Homoserine kinase, type II + Lysosomal cystine transporter + L-aspartate oxidase + CST complex subunit Stn1, N-terminal + Transcription termination factor Rho + Borealin, N-terminal + Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX + Collagen triple helix repeat + Small nuclear RNA activating complex (SNAPc), subunit SNAP43 + Ribosomal protein L27/L41, mitochondrial + N-acetyltransferase B complex, non-catalytic subunit + Anticodon-binding domain + Photosystem II PsbH, phosphoprotein + Ribosomal protein S13/S15, N-terminal + Cytochrome c oxidase biogenesis protein Cmc1-like + LL-diaminopimelate aminotransferase + RAD3/XPD family + Glycoside hydrolase, family 35 + tRNA-splicing endonuclease, subunit Sen54, N-terminal + MOZART2 family + Nucleolar GTP-binding protein 2, N-terminal domain + Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site + tRNA 2-selenouridine synthase + Tagatose/fructose phosphokinase + Sporulation stage V, protein R + mRNA splicing factor SYF2 + Aliphatic sulfonates-binding protein + Bacteriophage HK97-gp10, putative tail-component + Type II secretion system protein H + Ribbon-helix-helix protein, CopG + ZC3H15/TMA46 family, C-terminal + Vesiculovirus matrix + Biogenesis of lysosome-related organelles complex 1 subunit 1 + Type II secretion system protein M, periplasmic domain + Ethanolamine ammonia-lyase light chain + Type II secretion system, protein N + Asp/Glu racemase, active site 2 + Domain of unknown function DUF3441 + Vacuolar protein 14 C-terminal Fig4-binding domain + Proteasome activator complex subunit 4 C-terminal domain + STAG + Two-component sensor kinase, N-terminal + Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal + Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain + Phospholipase D/Transphosphatidylase + Peptidase S26B + Phosphotriesterase + FANCI solenoid 1 domain + Intraflagellar transport protein 43 + Phosphoribosylglycinamide formyltransferase, active site + Gemin2/Brr1 + Spt6, SH2 domain + Fanconi anemia group F protein + Nucleoporin Nup186/Nup192/Nup205 + RES domain + N-terminal acetyltransferase A, auxiliary subunit + Adenosine kinase + ATP synthase, F1 complex, epsilon subunit, mitochondrial + Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein + THO complex, subunit THOC1 + RAVE subunit 2/Rogdi + Carbon monoxide dehydrogenase subunit G + Methyltransferase, Rta_06860 family + tRNA (mo5U34)-methyltransferase-like + Proteasome activator Blm10, mid region + Radical SAM, C-terminal extension + Band 7, C-terminal extension + Nucleolar pre-ribosomal-associated protein 1, C-terminal domain + ERCC3/RAD25/XPB helicase, C-terminal domain + Histone-like protein H-NS + Zinc finger, LSD1-type + Serpin, conserved site + Orotate phosphoribosyl transferase domain + Replication gene A protein + Sirohaem synthase, dimerisation domain + Peroxiredoxin, C-terminal + Transcription factor TFIID, subunit 8, C-terminal + DNA primase, DnaB-helicase binding domain + Protein of unknown function DUF4464 + Para-aminobenzoate synthase, component I + DNA recombination/repair protein RecN + Signal peptidase complex subunit 2 + Proliferating cell nuclear antigen, PCNA, conserved site + Cell morphogenesis protein C-terminal + Domain of unknown functionDUF2779 + RPGR-interacting protein 1, first C2 domain + Group 4 capsule polysaccharide formation lipoprotein GfcB + Protein of unknown function DUF4238 + Protein of unknown function DUF4239 + Aconitase B, HEAT-like domain + Ribosomal protein L13e + DeoR-type HTH domain + Mitochondrial import receptor subunit TOM7 + Protein of unknown function DUF2214, membrane + Maltose/galactoside acetyltransferase + MMS19, C-terminal + Spp2/MOS2, G-patch domain + Inhibin, beta B subunit + Asparagine synthase + Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal + Coiled-coil domain-containing protein 90-like + Glycosyl-hydrolase family 116, N-terminal + Domain of unknown function DUF2384 + DIRP domain + Putative hydrolase RBBP9/YdeN + Lipopolysaccharide assembly, LptC-related + Serine-threonine protein kinase 19 + RLI1 + Bacteriophage KVP40, Orf299 + Anaphase-promoting complex, subunit CDC26 + Phosphoglucosamine mutase, bacterial type + Polysaccharide biosynthesis protein + Domain of unknown function DUF89 + HAT (Half-A-TPR) repeat + Condensin II complex subunit H2, N-terminal + NADH:ubiquinone/plastoquinone oxidoreductase, chloroplast chain 5, C-terminal + Cytochrome c oxidase, subunit Vb + Quinohemoprotein amine dehydrogenase, alpha subunit, domain 2 + DDE superfamily endonuclease domain + Cytochrome c-550 domain + Domain of unknown function DUF4433 + Ribonuclease Zc3h12a-like, NYN domain + ATP-dependent DNA helicase RecG, C-terminal domain + Topoisomerase I C-terminal domain + Serpin domain + Cancer susceptibility candidate protein 1 + Quinoprotein dehydrogenase-associated + Transmembrane protein 131-like + Sterol methyltransferase C-terminal + Molybdate ABC transporter, substrate-binding protein + Protein of unknown function DUF2491 + Uncharacterised protein family HI1736/YgjV + P-type trefoil, conserved site + RecD helicase-like helix-hairpin-helix domain + Recombination protein O, RecO + Phosphoenolpyruvate carboxylase + Flagellar hook-length control protein-like, C-terminal + Glycoside hydrolase, chitinase active site + Translation initiation factor 3, subunit 12, N-terminal, eukaryotic + Protein of unknown function DUF3007 + Ribosomal protein L19/L19e + Ferrous iron transporter FeoA domain + Phage shock protein, PspC + ATPase, V0 complex, c/d subunit + ATPase, V1/A1 complex, subunit E + Coenzyme F420:L-glutamate ligase-like domain + Protein of unknown function DUF599 + Translin family + Clathrin light chain + Domain of unknown function DUF4787 + MAM domain + Urocanase, C-terminal domain + Urocanase, N-terminal domain + Protein of unknown function DUF1028 + Phage-integrase repeat unit + 5-histidylcysteine sulfoxide synthase + Thiaminase II + CAAX prenyl protease 1, N-terminal + SMARCC, C-terminal + Uncharacterised domain UPF0702, alpha/beta domain + Ribosomal protein S5/S7, eukaryotic/archaeal + Ribosomal protein S4/S9, eukaryotic/archaeal + Ribosomal protein S5, eukaryotic/archaeal + Photosystem II D2 protein + Photosystem II CP43 reaction centre protein + ATP synthase, F0 complex, subunit b, bacterial + Photosystem II protein D1 + DNA mismatch repair protein Mlh1, C-terminal + Ribosomal protein L23/L25, conserved site + Myristoyl-CoA:protein N-myristoyltransferase, C-terminal + Hexokinase, N-terminal + Hexokinase, C-terminal + Myristoyl-CoA:protein N-myristoyltransferase, conserved site + Peptidase C14A, caspase catalytic domain + Inosine/uridine-preferring nucleoside hydrolase, conserved site + Protein of unknown function DUF2252 + Abortive bacteriophage infection, resistance + Glycosyl transferase WecB/TagA/CpsF + Mannonate dehydratase + PhnA protein + Head decoration protein D + Glycoside hydrolase, family 13, N-terminal + 5,10-methylenetetrahydrofolate reductase + UNC-45/Cro1/She4, central domain + Protein of unknown function DUF2927 + Protein of unknown function DUF2934 + SLC26A/SulP transporter + Polyamine biosynthesis domain, conserved site + Protein of unknown function DUF484 + Coatomer, gamma subunit, appendage, Ig-like subdomain + Meiotic recombination, Spo11 + Helical and beta-bridge domain + Low temperature requirement A + Polysaccharide pyruvyl transferase + Zinc finger, C2H2, LYAR-type + Deoxyribodipyrimidine photolyase-related protein + Uncharacterised protein YjbR + Protein of unknown function DUF421 + 26S proteasome non-ATPase regulatory subunit 5 + 2-phosphoglycolate phosphatase, prokaryotic + Phosphorylase pyridoxal-phosphate attachment site + Plasmid conjugal transfer TrbL/VirB6 + Uncharacterised protein family UPF0102 + Translation initiation factor IF6 + Ran-interacting Mog1 protein + YutG/PgpA domain + Sugar-phosphate isomerase, RpiB/LacA/LacB family + Tannase/feruloyl esterase + ATPase, V1 complex, subunit C + DNA topoisomerase I, catalytic core, alpha/beta subdomain + Peptidase U32, collagenase + Phenylacetic acid degradation B + Sulphate adenylyltransferase, large subunit + Hydantoinase/dihydropyrimidinase + Magnesium chelatase, ATPase subunit I + Magnesium chelatase, ATPase subunit D + Magnesium-chelatase, subunit H + Ribonuclease R + Beta-1,4-galactosyltransferase + Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal + Ribosomal protein L27e, conserved site + Beta tubulin + Gamma tubulin + Transcription elongation factor Spt5, NGN domain + Senescence/spartin-associated + Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain + Protein of unknown function DUF1280 + Paf1 complex subunit Cdc73, N-terminal domain + Uncharacterised protein family UPF0227/Esterase YqiA + Procyclic acidic repetitive + Ribosomal protein S27e, zinc-binding domain + RNA (C5-cytosine) methyltransferase, subfamily 9 + Pre-rRNA-processing protein RIX1, N-terminal + Protein of unknown function DUF3667 + Exosome-associated factor Rrp6, N-terminal + Lipase, GDSL, active site + Misato Segment II tubulin-like domain + Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain + Hemin uptake protein HemP + Kinase associated domain 1 (KA1) + Beta-catenin-like protein 1, N-terminal + N-acetylglucosaminyl phosphatidylinositol deacetylase-related + Metal-sensitive transcriptional repressor + Pyridoxal-phosphate binding site + Raptor, N-terminal CASPase-like domain + Ubiquitin carboxyl-terminal hydrolase, C-terminal + PhnA protein, N-terminal + Phospholipase C/D + CENP-S/Mhf1 + Protein of unknown function DUF1825 + Protein of unknown function DUF1826 + Protein of unknown function DUF1824 + Cytochrome f large domain + Proline dehydrogenase PutA, domain I + Transcription initiation factor IIF, beta subunit + Small-subunit processome, Utp11 + Leo1-like protein + NADPH-dependent F420 reductase + Acyl-ACP thioesterase + Quinohemoprotein amine dehydrogenase, alpha subunit domain III + Iodothyronine deiodinase + 2',3'-cyclic-nucleotide 3'-phosphodiesterase + Tricorn protease C1 domain + Photosynthesis system II assembly factor Ycf48/Hcf136-like domain + Ciliary BBSome complex subunit 2, N-terminal + Microvirus J protein-like + Cox20/FAM36A + Ubiquitously expressed transcript protein UXT + RTX toxin determinant A + Adenylate dimethylallyltransferase + Uncharacterised protein family UPF0642 + Translocon-associated protein (TRAP), alpha subunit + Ribosomal protein S23/S25, mitochondrial + Exosortase/Archaeosortase domain + Isocitrate lyase/phosphorylmutase, conserved site + DNA/RNA non-specific endonuclease, active site + 5-methylcytosine restriction system component + tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal + Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted + Protein of unknown function DUF1365 + Lysyl oxidase + Nitrile hydratase alpha /Thiocyanate hydrolase gamma + Tetrapyrrole biosynthesis, glutamyl-tRNA reductase + Putative glutamine amidotransferase type 2 + Protein of unknown function DUF2961 + Protein of unknown function DUF3228 + TRAPP III complex, Trs85 + Rubredoxin domain + RED-like, N-terminal + Plasmid pRiA4b, Orf3 + Chromatin modification-related protein Eaf6 + SUN domain + Adenylosuccinate lyase PurB, C-terminal + PUL domain + Alpha-L-fucosidase, metazoa-type + ATP-NAD kinase, PpnK-type, all-beta + Domain of unknown function DUF3641 + Outer membrane autotransporter barrel + Dyp-type peroxidase + Sec-independent protein translocase protein TatA/E + L-threonine dehydratase biosynthetic IlvA + Mediator of RNA polymerase II transcription subunit 22 + Protein of unknown function DUF993 + Nuclear cap-binding protein subunit 3 + CDC45 family + Helicase domain + Cytochrome b6-f complex subunit 6 + Protein of unknown function DUF4804 + Mitochondrial PGP phosphatase + Deoxyribose-phosphate aldolase + Double zinc ribbon + Protein RETICULATA-related + Protein of unknown function DUF3419 + UPF3 domain + Vacuolar (H+)-ATPase G subunit + Protein of unknown function DUF3684 + Tuftelin interacting protein, N-terminal domain + Protein of unknown function DUF2723 + Protein of unknown function DUF4202 + S100/Calbindin-D9k, conserved site + Protein of unknown function DUF779 + Rho protein GDP-dissociation inhibitor + Polyamine-modulated factor 1/Kinetochore protein NNF1 + Peptidase S13, D-Ala-D-Ala carboxypeptidase C + Cyclohexanecarboxyl-CoA dehydrogenase + 2-ketocyclohexanecarboxyl-CoA hydrolase + Catechol 2,3 dioxygenase + Conserved hypothetical protein CHP03214, putative allantoin-urate catabolism protein + Formamidopyrimidine-DNA glycosylase + Nucleolar, Nop52 + Cysteine dioxygenase type I + TRP-like family + FAR-17a/AIG1-like protein + Divergent polysaccharide deacetylase + Transcription regulator HTH, AraC- type + Domain of unknown function DUF4455 + ATP synthase YMF19-like, N-terminal + Cytochrome ubiquinol oxidase subunit 2 + Trans-aconitate 2-methyltransferase, C-terminal + Urocanase + Urocanase conserved site + Co-chaperone HscB, C-terminal oligomerisation domain + Dehydroquinase, class II, conserved site + EB1, C-terminal + Urease accessory protein UreG + Peptide chain release factor eRF1/aRF1 + Glucose-fructose oxidoreductase, bacterial + Phosphatidate cytidylyltransferase, mitochondrial + Alpha-2-glucosyltransferase Alg10 + Histidine phosphotransferase ChpT, C-terminal + TFIIH subunit TTDA/Tfb5 + Kri1-like, C-terminal + Domain of unknown function DUF2846 + NADH:ubiquinone oxidoreductase, B18 subunit + HicA mRNA interferase family + Zinc finger, C3HC-like + H-type lectin domain + Eukaryotic translation initiation factor 3 subunit E, N-terminal + Vacuolar ATPase assembly integral membrane protein Vma21 + Protein of unknown function DUF2474 + Ribulose bisphosphate carboxylase small chain, domain + Transthyretin/hydroxyisourate hydrolase + Ribosomal protein S26e + Aliphatic acid kinase, short-chain + Scaffold protein D + Eukaryotic-type methylenetetrahydrofolate reductase + Ubiquinol cytochrome reductase, transmembrane domain + Non-structural maintenance of chromosome element 4, C-terminal + Helicase HerA, central domain + H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote + Adenosine/adenine deaminase + Coenzyme PQQ biosynthesis protein C + Coenzyme PQQ biosynthesis protein E, bacteria + Interferon alpha-inducible protein 6/27 + Ribosomal RNA processing protein 8 + Photosystem II PsbM + Microcystin LR degradation protein MlrC, C-terminal + Prenylcysteine lyase + Ribosomal protein S4e, N-terminal, conserved site + Tweety + Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like domain + Ribosomal protein L24e, conserved site + DNA replication licensing factor Mcm6 + DNA replication licensing factor Mcm + D-ribose pyranase RbsD/L-fucose mutarotase FucU + Endoribonuclease XendoU + RNA helicase UPF1, UPF2-interacting domain + DNA replication licensing factor Mcm2 + FGFR1 oncogene partner (FOP), N-terminal dimerisation domain + Mini-chromosome maintenance complex protein 4 + DNA replication licensing factor Mcm3 + mRNA decapping protein 2, Box A domain + Timeless C-terminal + SPARC/Testican, calcium-binding domain + Splicing factor 3B subunit 1 + Uncharacterised protein family UPF0564 + Transcription factor LuxR-like, autoinducer-binding domain + Coenzyme F420:L-glutamate ligase + Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA + Origin recognition complex, subunit 3 + PdxS/SNZ N-terminal domain + Exosome complex component, N-terminal domain + GAG-pre-integrase domain + Domain of unknown function DUF4174 + Glycoside hydrolase family 18, catalytic domain + Legume lectin domain + DBP10, C-terminal + GINS subunit, domain A + Iron-sulphur-dependent L-serine dehydratase single chain form + Helix-turn-helix, type 11 + Protein of unknown function DUF4591 + GCK + RNA polymerase II, heptapeptide repeat, eukaryotic + Type II secretion system GspE + Peptidase M22, conserved site + F-actin capping protein, alpha subunit, conserved site + 3-hydroxyanthranilic acid dioxygenase + Exocyst complex component EXOC3/Sec6 + HDIG domain + Sin3, C-terminal + MraZ domain + Ribosomal protein L6, conserved site-2 + dTDP-glucose 4,6-dehydratase + Serine O-acetyltransferase + Zinc finger, DksA/TraR C4-type, bacteria + Ribonuclease HII, helix-loop-helix cap domain + Protein of unknown function DUF1127 + Ribosomal protein S25 + Eukaryotic translation initiation factor 3 subunit C, N-terminal domain + Proteasome assembly chaperone 3 + COG complex component, COG2, C-terminal + Protein of unknown function DUF2608 + Ribosome maturation protein SBDS, N-terminal + BING4, C-terminal domain + Sde2 N-terminal domain + BP28, C-terminal domain + CPL domain + UreE urease accessory, N-terminal + Mago nashi protein + Phthalate dioxygenase reductase + Ada DNA repair, metal-binding + Transcription regulator YcdC, C-terminal + DNA polymerase subunit Cdc27 + Tafazzin + Schlafen, AAA domain + Anti-sigma factor antagonist + RelB antitoxin/Antitoxin DinJ + GTP cyclohydrolase I + Quinoprotein dehydrogenase, conserved site + Choline ABC transporter, substrate-binding protein + ABC transporter, urea, ATP-binding protein, UrtD + ABC transporter, choline, permease protein + CRM1 C-terminal domain + Urea transporter + RFT1 + Anaphase-promoting complex subunit 2, C-terminal + MiaB-like tRNA modifying enzyme + ATPase assembly factor ATP10 + HEPN domain + RNA-recognition motif (RRM) Nup35-type domain + L-asparaginase, C-terminal domain + Asparaginase/glutaminase, active site 2 + Ribulose bisphosphate carboxylase, large chain, active site + Molybdate ABC transporter, ATP-binding protein + Sulphate ABC transporter, permease protein CysT + Phosphate ABC transporter, permease protein PstC + Molybdate ABC transporter, permease protein + Sas10 C-terminal domain + Cytochrome b-c1 complex subunit 9 + Ribosome maturation protein SBDS, C-terminal + Allantoicase + Ku70/Ku80 C-terminal arm + CDKN3 domain + TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain + Wings apart-like protein + ThiC-associated domain + Cleavage stimulation factor subunit 2, hinge domain + FlgD Ig-like domain + N-acetyltransferase ESCO, zinc-finger + Micro-fibrillar-associated protein 1, C-terminal + Mitochondrial degradasome RNA helicase subunit, C-terminal domain + Protein of unknown function DUF3293 + Pre-mRNA splicing Prp18-interacting factor + Ribosomal protein S1 + Signal recognition particle, SRP72 subunit, RNA-binding + mRNA splicing factor, Cwf18 + Conserved oligomeric Golgi complex, subunit 4 + SPFH domain, YdjI-like + Type I secretion membrane fusion protein, HlyD family + Phasin, subfamily 1 + Pyruvate, phosphate dikinase + Ribonucleotide reductase, adenosylcobalamin-dependent + Domain of unknown function DUF403 + Transcription activator PspF + Succinate dehydrogenase, hydrophobic membrane anchor + Phage shock protein, PspA + Adenosine/AMP deaminase active site + Photosystem I Ycf4, assembly + Bacteriochlorophyll/chlorophyll synthetase + Phosphotransferase system, fructose-specific IIB subunit + Uncharacterised protein family UPF0066, conserved site + Uncharacterised domain, di-copper centre + Flagellar hook-associated protein 1 + ETC complex I subunit + Sec20 + Erg28 + ISWI, HAND domain + Peptide-N-glycosidase F, C-terminal + Peptide-N-glycosidase F, N-terminal + Translation elongation factor SelB, winged helix, type 3 + Phosphoenolpyruvate carboxykinase (ATP), conserved site + CofH family + Uncharacterised domain NUC130/133, N-terminal + Arginine N-succinyltransferase AstA/AruG + DNA-directed RNA polymerase, subunit beta'' + NOG, C-terminal + DNA-directed RNA polymerase, subunit beta-prime + DNA-directed RNA polymerase, subunit gamma + RNA polymerase sigma factor RpoH, proteobacteria + NAD-dependent DNA ligase + C4-type zinc-finger of DNA polymerase delta + Bacterial periplasmic spermidine/putrescine-binding protein + Thiosulfohydrolase SoxB + Sulfur oxidation c-type cytochrome SoxX + TusA-like domain + Thiosulfate oxidation carrier complex protein SoxZ + GRASP55/65 PDZ-like domain + SSRP1 domain + tRNAHis guanylyltransferase catalytic domain + Siderophore-interacting protein + Primase, C-terminal 2 + tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 + Guanine nucleotide-binding protein-like 3, N-terminal domain + Fcf2 pre-rRNA processing + SRP40, C-terminal + Urease accessory protein UreE, C-terminal domain + Hypoxia-inducible factor 1-alpha inhibitor, domain II + F-actin-capping protein subunit alpha + Maltose transport system permease protein MalF N-terminal domain + Domain of unknown function DUF4537 + Domain of unknown function DUF4515 + Ribosomal protein S6, conserved site + Zeta-carotene desaturase + Transcription factor IIA, alpha/beta subunit + Protein of unknown function DUF4505 + Diphthamide synthase domain + Uncharacterised protein family UPF0145 + Protein of unknown function DUF2452 + Bacteriophage phiNM3, A0EWY4 + Sodium:dicarboxylate symporter, conserved site + Phage tail collar domain + CCR4-NOT transcription complex subunit 1, CAF1-binding domain + Knr4/Smi1-like domain + Vacuolar protein sorting-associated protein 8, central domain + Ribosomal protein S19e + Translocation protein Sec62 + Translocation protein Sec66 + Autophagy-related, C-terminal + Chalcone isomerase + DTXR-type HTH domain + Symplekin C-terminal + Pyrimidine nucleoside phosphorylase, C-terminal + Peptidase M10A + PdxT/SNO family, conserved site + TonB-dependent siderophore receptor + Bacterial TonB-dependent receptor + Protein of unknown function DUF3131 + Protein of unknown function DUF604 + Succinate semialdehyde dehydrogenase + Citrate synthase, eukaryotic-type + N-acetylneuraminic acid synthase, N-terminal + Transmembrane adaptor Erv26 + Domain of unknown function DUF4472 + Domain of unknown function DUF1619 + Cornichon + Lipase/vitellogenin + Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain + Domain of unknown function DUF4440 + NUC194 + Helix-turn-helix, HxlR type + Protein of unknown function DUF1168 + Microsomal signal peptidase 12kDa subunit + Ribosomal protein L30, conserved site + KRR1 interacting protein 1 + Phospholipase C/P1 nuclease domain + Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain + General secretion pathway protein K + Beta-glucan synthesis-associated, SKN1 + Isochorismatase + MIF4G-like, type 1 + MIF4G-like, type 2 + Protein of unknown function DUF3775 + Flagellar motor stator, MotA + Glutamate racemase + Protein of unknown function DUF2130 + Protein of unknown function DUF2380 + Uncharacterised domain UPF0547 + Autophagy-related protein 13 + Knottin, scorpion toxin-like + Nuclease associated modular domain 3 + Domain of unknown function DUF4140 + DML1/Misato, tubulin domain + Fructosamine/Ketosamine-3-kinase + 4-hydroxybenzoate 3-monooxygenase + ATP-dependent Clp protease ATP-binding subunit ClpA + Uncharacterised protein family AroM + Occludin homology domain + GPCR, family 2, secretin-like + RNA polymerase sigma factor 70, ECF, conserved site + Delta tubulin + Asparagine synthase, glutamine-hydrolyzing + Eukaryotic translation initiation factor 3 subunit G, N-terminal + Streptogrisin prodomain + RNA polymerases, subunit N, zinc binding site + Splicing factor 1, helix-hairpin domain + UNC-50 + SUF system FeS cluster assembly regulator + Radial spoke 3 + NnrS + Arylsulfotransferase, C-terminal + Ecotin, C-terminal + DBINO domain + Lipoxygenase, conserved site + Tol-Pal system beta propeller repeat-containing protein, TolB + Thiamine-monophosphate kinase + Thiamin pyrophosphokinase + SNF5/SMARCB1/INI1 + Biopolymer transport, TolR + Alpha/beta-hydrolase, catalytic domain + Protein of unknown function DUF2451, C-terminal + Protein kinase A anchor protein, nuclear localisation signal domain + Zinc finger protein DZIP1, N-terminal + Heme-NO binding + Purine nucleoside permease + DeoR C-terminal sensor domain + RIO kinase, conserved site + PDZ-like domain + ODR-4-like + Domain of unknown function DUF1338 + Ribosome control protein 1 + Cell division cycle protein 123 + Anthranilate synthase component I, PabB-like + Protein of unknown function DUF1849 + Glycoside hydrolase, family 77 + Protein of unknown function DUF4539 + Uncharacterised domain, YlbE + Flagellar basal-body rod FlgF + Flagellar basal-body rod FlgG + Metallophosphoesterase, DNA ligase-associated + Histone RNA hairpin-binding protein, RNA-binding domain + Conserved oligomeric Golgi complex subunit 8 + Protein of unknown function DUF5309 + MD-2-related lipid-recognition domain + Ribosomal protein L6, chloroplast + PA14 domain + Coiled-coil domain-containing protein 24 + Alkyl hydroperoxide reductase subunit C + Ribosomal protein L37, mitochondrial + Cdc37, Hsp90 binding + Biotin-independent malonate decarboxylase, beta subunit + TFIIH p62 subunit, N-terminal + YAP-binding/ALF4/Glomulin + Photosystem II PsbN + Glycosyl hydrolase 94 + Clusterin-associated protein-1 + Rod shape-determining protein RodA + Chitin binding domain + Glycoside hydrolase, family 32, active site + Aldose 1-epimerase, conserved site + Phosphomannose isomerase, type I, conserved site + UPF0255 family + Photosystem II PsbU, oxygen evolving complex + TATA element modulatory factor 1 TATA binding + Lipocalin family conserved site + Beta-carotene 15,15'-monooxygenase, Brp/Blh family + Protein DPCD + Eukaryotic rRNA processing + Excalibur calcium-binding domain + Protein of unknown function DUF1823 + NolW-like + Meiotic nuclear division protein 1 + Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase + LCCL domain + Phage shock protein B + Glutamine synthetase class-I, adenylation site + Ribosomal protein L21e + Alpha carbonic anhydrase + ATPase, vacuolar ER assembly factor, Vma12 + Patatin-related protein + Transposase IS204/IS1001/IS1096/IS1165, zinc-finger + T-complex protein 1, epsilon subunit + T-complex protein 1, gamma subunit + T-complex protein 1, beta subunit + T-complex protein 1, delta subunit + T-complex protein 1, alpha subunit + Cytochrome b-c1 complex subunit 7 + Transcription initiation factor IID, subunit 13 + TATA-box binding protein + 7Fe ferredoxin + Glycosyl transferase, family 35 + Photosystem I PsaG/PsaK protein + Ribosomal RNA small subunit methyltransferase J + Uridine kinase-like + Coatomer, alpha subunit, C-terminal + Cysteine desulfurase IscS + Protein of unknown function DUF1289 + Protein of unknown function DUF1294 + Putative rRNA methylase + Glycosyl hydrolase family 95, N-terminal domain + Protein Thf1 + Photosystem I PsaK, reaction centre + Photosystem I protein PsaC + DNA ligase D, polymerase domain + Rad21/Rec8-like protein, N-terminal + DNA ligase D + Popeye protein + YppE-like domain + Nucleoporin, NSP1-like, C-terminal + Calcium permeable stress-gated cation channel 1, N-terminal transmembrane domain + N-acetylglucosaminyltransferase, MurG + CRISPR-associated protein Cas1 + FGGY carbohydrate kinase, pentulose kinase + Carbohydrate kinase, thermoresistant glucokinase + Glutamate synthase, NADH/NADPH, small subunit 2 + Flagellar FlaF + Glutathionylspermidine synthase, pre-ATP-grasp-like domain + Type IV secretion system, VirB10 / TraB / TrbI + MRN complex-interacting protein + Starter unit:ACP transacylase + Protein FAM72 + Uncharacterised conserved protein UCP028704, OpgC + Putative phosphate transport regulator + Protein of unknown function DUF2478 + Anamorsin + Pre-rRNA-processing protein TSR2 + Colon cancer-associated Mic1-like + Protein of unknown function DUF1269, membrane associated + Protein of unknown function DUF2093 + Domain of unknown function DUF2126 + Protein of unknown function DUF3734 + Protein of unknown function DUF2838 + Domain of unknown function DUF3449 + Sensor N-terminal transmembrane domain + Phosphopentomutase DeoB cap domain + Translation initiation factor 2, alpha subunit, middle domain + Translation initiation factor 2, alpha subunit, C-terminal + Sodium:neurotransmitter symporter + Branched-chain amino acid transport, AzlD + Pre-mRNA-splicing factor SPF27 + EcoEI R protein C-terminal domain + Mitochondrial inner membrane protein Mitofilin + Transcription factor IIIC, subunit 5 + Polycomb protein, VEFS-Box + Cactin, C-terminal + Cullin, conserved site + Phosphotransferase/anion transporter + VASt domain + Autophagy-related protein 5 + DNA primase large subunit, eukaryotic/archaeal + SlyX + Vps53-like, N-terminal + DNA modification/repair radical SAM protein, putative + Peptidase S59, nucleoporin + Ribosomal protein S6e + S1/P1 nuclease + Domain of unknown function DUF382 + MYND-like zinc finger, mRNA-binding + Ribosomal RNA small subunit methyltransferase F, N-terminal + Protein TIC110, chloroplastic + Cdc37, N-terminal domain + Precorrin-2 C(20)-methyltransferase domain + Ribonuclease III + Ubiquitin-activating enzyme E1, conserved site + DNA-binding, RecF, conserved site + Zinc-binding domain + Muconolactone isomerase domain + 1,2-phenylacetyl-CoA epoxidase, subunit A/C + Chromosome transmission fidelity protein 8 + Uncharacterised conserved protein UCP033924 + RIO2 kinase winged helix domain, N-terminal + Death-like domain of Spt6 + Domain of unknown function DUF2231, transmembrane + Galactosyltransferase, N-terminal + Possible tRNA binding domain + 2-isopropylmalate synthase + Sulphate ABC transporter permease protein 2 + Histone acetyltransferase ELP3 + Translation elongation factor, selenocysteine-specific + L-seryl-tRNA(Sec) selenium transferase + Haemolysin A /rRNA methyltransferase TlyA + Helicase XPB/Ssl2 + Poly-beta-hydroxybutyrate polymerase N-terminal + Mitotic-spindle organizing protein 1 + Polyadenylate binding protein, human types 1, 2, 3, 4 + Protein of unknown function DUF4345 + Glutaminase + Probable phospholipid ABC transporter-binding protein MlaD + Peptidase M24A, methionine aminopeptidase, subfamily 2 + Ribosomal biogenesis regulatory protein + Conserved hypothetical protein CHP02594 + CRISPR-associated protein Cas5, N-terminal + Colicin immunity protein/pyocin immunity protein + Photosystem II PsbZ, reaction centre + NADH:ubiquinone oxidoreductase, subunit G + ATP binding protein MinD, bacterial-type + ATP-dependent helicase HrpB + Copine + Protein of unknown function DUF543 + Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal + Mss4 + N6 adenine-specific DNA methyltransferase, D21 class + Pre-mRNA-splicing factor Cwf15/Cwc15 + PT repeat + Dolichol phosphate-mannose biosynthesis regulatory + Steroid receptor RNA activator-protein/coat protein complex II, Sec31 + Signal recognition particle, SRP14 subunit + tRNA wybutosine-synthesis + Adenylate cyclase-associated CAP, C-terminal + Protein of unknown function DUF2076 + Transferase 1, rSAM/selenodomain-associated + Coenzyme PQQ synthesis D + Oxygen-evolving enhancer protein 3 + NADH dehydrogenase subunit 5, C-terminal + DNA-directed RNA polymerase, helix hairpin domain + Protein of unknown function DUF1674 + Putative deacetylase LmbE-like domain + Lycopene cyclase + Domain of unknown function DUF1737 + DNA methyltransferase 1-associated 1 + Vanillyl-alcohol oxidase/Cytokinin dehydrogenase C-terminal domain + FR47-like + DNA polymerase delta, subunit 4 + Mitochondrial glycoprotein + Opine dehydrogenase + Malonyl-CoA decarboxylase, N-terminal + Nrap protein, domain 6 + Conserved hypothetical protein CHP03083, actinobacterial-type + Protein of unknown function DUF727 + PQQ-dependent dehydrogenase, methanol/ethanol family + Conserved hypothetical protein CHP03084 + Ribosomal protein S36, mitochondrial + Bromodomain associated domain + Glycosyltransferase 2-like, prokaryotic type + Fas apoptotic inhibitory molecule 1 + DNA replication complex GINS protein SLD5, C-terminal + Glycosyl hydrolase family 63, N-terminal + Putative L,D-transpeptidase catalytic domain + Gentisate 1,2-dioxygenase + dCTP deaminase + Centromere protein CENP-B, C-terminal domain + Proteinase inhibitor I11, ecotin domain + Ribosomal protein L44e + Ubiquinol-cytochrome C reductase hinge domain + Homospermidine synthase-like, domain + Vacuolar protein sorting-associated protein Ist1 + Luc7-related + Glucanosyltransferase + NADH-ubiquinone oxidoreductase, 21kDa subunit, N-terminal + Histone-binding protein RBBP4, N-terminal + Anaphase-promoting complex subunit 5 + 1-acyl-sn-glycerol-3-phosphate acyltransferase + Diphthine synthase + BCP1 family + Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal + Oxygen-independent coproporphyrinogen III oxidase HemN + Protein kish + Putative methionine gamma-lyase + Uncharacterised protein family, methyltransferase, Williams-Beuren syndrome + Protein of unknown function DUF3326 + Cleavage and polyadenylation specificity factor 2, C-terminal + Mannosyltransferase, DXD + Methyl-accepting chemotaxis protein (MCP) signalling domain + DNA topoisomerase VI, subunit A + Ribosomal protein L36e + Ribosomal protein S27a + Lysine-tRNA ligase + Transcriptional coactivator Hfi1/Transcriptional adapter 1 + SGF29 tudor-like domain + Hepatocellular carcinoma-associated antigen 59 + Ubiquinone biosynthesis hydroxylase UbiH/COQ6 + HflK + Mak16 protein + Nitric oxide synthase-interacting protein, zinc-finger + Protein of unknown function DUF5076 + Nitrate reductase, alpha subunit, N-terminal + Putative Actinobacterial Holin-X, holin superfamily III + FACT complex subunit Spt16p/Cdc68p + Histone deacetylation protein Rxt3 + U4/U6.U5 small nuclear ribonucleoprotein 27kDa protein + E3 ubiquitin ligase, BRE1 + CFAP91 domain + Type IV secretion system, VirB3 / TrbD / AvhB + Uncharacterised protein family UPF0114, bacteria + DNA gyrase, subunit B + Initiation factor 2B alpha/beta/delta + Transmembrane protein 18 + Frataxin conserved site + Glutathione-dependent formaldehyde-activating enzyme + Phosphotransferase system, EIIB component, type 2/3 + Gemin6 + Beta-catenin-interacting ICAT + Type III secretion system inner membrane R protein + Ferredoxin-dependent bilin reductase + Kinetochore protein Nuf2 + Cell division protein FtsQ/DivIB + Mediator complex, subunit Med7 + SMN complex, gem-associated protein 7 + Gluconate 2-dehydrogenase subunit 3 + Protein of unknown function DUF2039 + Protein of unknown function DUF2181 + Smg8/Smg9 + BAR domain + Domain of unknown function DUF1741 + siRNA-mediated silencing protein NRDE-2 + Cytochrome B561-related + Prp31 C-terminal + Peptidase M32, carboxypeptidase Taq + SDA1 domain + Protein of unknown function DUF726 + SH3-binding 5 + Glutamine synthetase, type III + Carbon catabolite-derepressing protein kinase, ubiquitin-associated domain + Protein of unknown function DUF1769 + A1 cistron-splicing factor, AAR2 + Protein of unknown function DUF541 + Ribosomal protein PSRP-3/Ycf65 + Histidinol-phosphate phosphatase + P-type ATPase, subfamily V + Kinase phosphorylation domain + RNA polymerase sigma factor 54, DNA-binding + Domain of unknown function DUF4709 + Ndc10, domain 2 + THO complex subunit 2, N-terminal domain + Putative 4-mercaptohistidine N1-methyltranferase, OvoA C-terminal domain + Flagellar hook protein FlgE + TUP1-like enhancer of split + Lipid A biosynthesis, N-terminal + Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal + DNA recombination/repair protein Rad51 + Usg-like + CAS/CSE, C-terminal + STELLO-like + Transcription initiation factor IIF, alpha subunit + Spindle assembly checkpoint component Mad1 + Tyrosine/nicotianamine aminotransferase + Fumarylacetoacetase + ATP synthase, F0 complex, subunit C, bacterial/chloroplast + Splicing factor 3A subunit 1 + RAVE complex protein Rav1 C-terminal + A-kinase anchor protein 28kDa + TUG ubiquitin-like domain + Copper amine oxidase, C-terminal + DNA-directed RNA polymerase I subunit RPA2, domain 4 + Autophagy-related protein 101 + Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site + Neprosin + MEMO1 family + FAM194 family + Ribosomal protein L7A/L8 + ERCC1/RAD10/SWI10 family + Transcription-repair coupling factor + rRNA small subunit methyltransferase B + Protoporphyrinogen oxidase + Ragulator complex protein LAMTOR5 + PAN2 domain + RNA 3'-terminal phosphate cyclase, insert domain + Domain of unknown function DUF3376 + Cyclin-dependent kinase, regulatory subunit + RNA polymerase, subunit H/Rpb5 C-terminal + MCP methyltransferase, CheR-type + Homologous-pairing protein 2 + Ecd family + NIF system FeS cluster assembly, NifU, N-terminal + XAP5 protein + Creatininase/formamide hydrolase + SHQ1 protein + DYW domain + DNA-directed RNA polymerase, 14-18kDa subunit, conserved site + Nop2p + Oxygen-dependent choline dehydrogenase + Glycogen debranching enzyme, C-terminal + Equilibrative nucleoside transporter + Transcription regulator LexA + Mevalonate kinase + Threonine dehydratase, catabolic + Transcription initiation factor TFIID, 23-30kDa subunit + Ribosomal protein L14e domain + ANTAR domain + NF-kappa-B-activating protein + Arc-like DNA binding domain + Putative nucleotidyltransferase + Solute carrier family 35 member SLC35F1/F2/F6 + Protein of unknown function DUF2177, membrane + Ribose 5-phosphate isomerase B + RNA polymerase sigma factor RpoD, C-terminal + Mannitol dehydrogenase, conserved site + F420-dependent oxidoreductase-predicted, MSMEG2249 + PQQ-dependent catabolism-associated CXXCW motif + Gamma-secretase aspartyl protease complex, presenilin enhancer-2 subunit + DNA polymerase III delta, N-terminal + Myeloid leukemia factor + ZinT domain + Coenzyme A transferase active site + Coiled-coil domain of unkwon function DUF2037 + Uncharacterised protein family FPL + Vesicle transport protein, Use1 + DDRGK domain containing protein + Protein of unknown function DUF2046 + Ribosome-assembly protein 3 + Protein of unknown function DUF3037 + Peptidase S1A, chymotrypsin family + Pumilio RNA-binding repeat + Muconolactone delta-isomerase + Cytochrome c oxidase, monohaem subunit/FixO + Polyribonucleotide nucleotidyltransferase + Mad3/Bub1 homology region 1 + Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain + LURP1-related protein domain + Protein of unknown function DUF423 + Serine-threonine protein phosphatase, N-terminal + Uncharacterised protein family UPF0311 + FkbH domain + MoaD, archaeal-type + Enolase-phosphatase E1 + Cobinamide kinase/cobinamide phosphate guanyltransferase + Protein of unknown function DUF1428 + Glycosylphosphatidylinositol-mannosyltransferase I, PIG-X/PBN1 + PPP domain + Clp1, N-terminal beta-sandwich domain + RNA polymerase III, subunit Rpc25 + Dynamin, GTPase region, conserved site + Dynein light chain, type 1/2, conserved site + Domain of unknown function DUF3598 + Cilia- and flagella-associated protein 206 + RIB43A + Seipin family + Lipase maturation factor + Domain of unknown function DUF1624 + Folate receptor-like + CagE, TrbE, VirB component of type IV transporter system, central domain + UDP-galactopyranose mutase + Mediator complex, 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Oceanospirillaceae + + + Bacteria + Proteobacteria + Gammaproteobacteria + Pseudomonadales + + + Bacteria + Proteobacteria + Gammaproteobacteria + Pseudomonadales + Moraxellaceae + Psychrobacter + + + Bacteria + Proteobacteria + Gammaproteobacteria + Thiotrichales + + + Bacteria + Proteobacteria + Gammaproteobacteria + Thiotrichales + Piscirickettsiaceae + Cycloclasticus + + + Bacteria + Proteobacteria + Gammaproteobacteria + Xanthomonadales + Xanthomonadaceae + Stenotrophomonas + + + Bacteria + Proteobacteria + Gammaproteobacteria + Xanthomonadales + Xanthomonadaceae + Stenotrophomonas + Stenotrophomonas_maltophilia + + + Bacteria + Proteobacteria + Oligoflexia + Bacteriovoracales + Halobacteriovoraceae + Halobacteriovorax + Halobacteriovorax_marinus + + + Bacteria + Spirochaetes + + + Bacteria + Spirochaetes + Spirochaetia + Spirochaetales + + + Bacteria + Tenericutes + + + Bacteria + Tenericutes + Mollicutes + Acholeplasmatales + Acholeplasmataceae + + + Bacteria + Verrucomicrobia + + + Eukaryota + Oligohymenophorea + + + Eukaryota + Spirotrichea + + + Eukaryota + Apicomplexa + Gregarinasina + Eugregarinorida + + + Eukaryota + Bacillariophyta + + + Eukaryota + Metazoa + + + Mitochondria + marine_metagenome + + Winged helix-turn-helix DNA-binding domain + Aldolase-type TIM barrel + ABC transporter-like + Rossmann-like alpha/beta/alpha sandwich fold + Immunoglobulin-like fold + Nucleotide-diphospho-sugar transferases + FAD/NAD(P)-binding domain + Tetratricopeptide-like helical domain + Pyridoxal phosphate-dependent transferase, subdomain 2 + Pyridoxal phosphate-dependent transferase, major region, subdomain 1 + 4Fe-4S ferredoxin, iron-sulphur binding, conserved site + ABC transporter, conserved site + Histidine kinase-like ATPase, C-terminal domain + Signal transduction response regulator, receiver domain + Ribonuclease H-like domain + 4Fe-4S ferredoxin-type, iron-sulphur binding domain + ABC transporter type 1, transmembrane domain MetI-like + Alpha/Beta hydrolase fold + Glycosyl transferase, family 1 + Glycosyltransferase 2-like + Radical SAM + Metallo-beta-lactamase + Alkaline phosphatase-like, alpha/beta/alpha + Integrase-like, catalytic domain + Glycosyltransferase subfamily 4-like, N-terminal domain + Galactose-binding domain-like + Class I glutamine amidotransferase-like + Short-chain dehydrogenase/reductase SDR + Pectin lyase fold + ABC transporter, FecCD/TroCD-like + Ribosomal protein S5 domain 2-type fold, subgroup + Integrase, catalytic domain + RmlC-like jelly roll fold + HAD-like domain + Signal transduction histidine kinase-related protein, C-terminal + DNA methylase, N-6 adenine-specific, conserved site + Thiolase-like + WD40/YVTN repeat-like-containing domain + AMP-dependent synthetase/ligase + PIN domain-like + DNA methylase N-4/N-6 + GNAT domain + ABC transporter, permease + Major facilitator superfamily + Metallo-dependent phosphatase-like + PAS domain + Integrase/recombinase, N-terminal + GAF domain-like + Beta-grasp domain + Helicase, C-terminal + Sulfatase, N-terminal + Signal transduction histidine kinase, dimerisation/phosphoacceptor domain + Amidohydrolase-related + ATPase, AAA-type, core + Methyltransferase type 11 + Metal-dependent hydrolase, composite domain + ATP-grasp fold, subdomain 1 + Aminotransferase, class I/classII + Oxidoreductase, N-terminal + Integrase, catalytic core + Small GTP-binding protein domain + TonB-dependent receptor, beta-barrel + Arc-type ribbon-helix-helix + NAD-dependent epimerase/dehydratase + Acyl-CoA dehydrogenase/oxidase, N-terminal + Ribokinase-like + Acyl-CoA dehydrogenase/oxidase C-terminal + RNA polymerase sigma-70 like domain + K homology domain-like, alpha/beta + RNA polymerase sigma-70 region 2 + Transposase, Tn5-like, core + Cro/C1-type helix-turn-helix domain + Tetratricopeptide repeat + 6-phosphogluconate dehydrogenase, domain 2 + Crotonase superfamily + Hexapeptide repeat + Six-bladed beta-propeller, TolB-like + DNA methylase, adenine-specific + CBS domain + Aminoacyl-tRNA synthetase, class Ia, anticodon-binding + GTP binding domain + Nucleophile aminohydrolases, N-terminal + Short-chain dehydrogenase/reductase, conserved site + HD domain + Solute-binding protein family 5 domain + Transcription factor, GTP-binding domain + Acyl-CoA oxidase/dehydrogenase, central domain + NAD(P)-binding domain + Restriction/modification DNA-methylase + Prokaryotic N-terminal methylation site + DEAD/DEAH box helicase domain + GGDEF domain + Nucleotidyl transferase domain + TRAP C4-dicarboxylate transport system permease DctM subunit + Helicase/UvrB, N-terminal + PIN domain + Acriflavin resistance protein + Succinyl-CoA synthetase-like + Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II + TTHA1013/TTHA0281-like + Flavoprotein-like domain + DegT/DnrJ/EryC1/StrS aminotransferase + Uroporphyrinogen decarboxylase (URO-D) + Xylose isomerase-like, TIM barrel domain + EamA domain + Tryptophan synthase beta subunit-like PLP-dependent enzyme + von Willebrand factor, type A + GAF domain + CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 + Carbohydrate kinase PfkB + Secretion system C-terminal sorting domain + Cobalamin (vitamin B12)-binding domain + Transposase, IS4-like + AMP-binding enzyme, C-terminal domain + AMP-binding, conserved site + Aminotransferase class-III + CoA-transferase family III domain + Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase + Aldehyde ferredoxin oxidoreductase, C-terminal + DHS-like NAD/FAD-binding domain + Polymerase, nucleotidyl transferase domain + Nitroreductase-like + Enolase C-terminal domain-like + Restriction endonuclease, type I, HsdS + Alcohol dehydrogenase, N-terminal + Transposase IS200-like + Aminoacyl-tRNA synthetase, class Ia + Integrase, SAM-like, N-terminal + Aminoacyl-tRNA synthetase, class I, conserved site + Leucine-binding protein domain + Aldehyde dehydrogenase domain + OmpR/PhoB-type DNA-binding domain + TonB-dependent receptor, plug domain + NUDIX hydrolase domain + Aminotransferase class V domain + CoA-transferase family III + Cytochrome c-like domain + Aldehyde dehydrogenase N-terminal domain + Phosphoribosyltransferase domain + Mur ligase, central + Calcineurin-like phosphoesterase domain, ApaH type + LysR, substrate-binding + Ferritin-related + Thiamine pyrophosphate enzyme, C-terminal TPP-binding + WD40-like Beta Propeller + Transcription regulator HTH, LysR + RNA-binding S4 domain + Alpha/beta hydrolase fold-1 + Glutamine amidotransferase + Alcohol dehydrogenase, C-terminal + Peptidase M20 + Molybdopterin oxidoreductase + tRNA (guanine-N1-)-methyltransferase, N-terminal + RNA polymerase sigma factor 70, region 4 type 2 + Aspartate/glutamate/uridylate kinase + AIR synthase-related protein, C-terminal domain + Nitroreductase + Oligopeptide/dipeptide ABC transporter, C-terminal + CoA-binding + Aldehyde ferredoxin oxidoreductase, N-terminal + DNA-binding HTH domain, TetR-type + FMN-binding split barrel + RNA polymerase sigma factor 54 interaction domain + Ribosomal protein L2 domain 2 + Carbon-nitrogen hydrolase + ABC transporter permease protein domain + Transcription regulator HTH, GntR + PurM-like, N-terminal domain + TRAP transporter solute receptor DctP/TeaA + TOPRIM domain + Radical SAM, alpha/beta horseshoe + Aldehyde ferredoxin oxidoreductase, domain 3 + NADP-dependent oxidoreductase domain + ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain + GIY-YIG nuclease superfamily + Thiolase, N-terminal + S1 domain + PLP-binding barrel + Crontonase, C-terminal + Transcription regulator LuxR, C-terminal + Glycosyl hydrolase, five-bladed beta-propellor domain + Aldehyde ferredoxin oxidoreductase, domain 2 + Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding + Transketolase-like, pyrimidine-binding domain + HAD hydrolase, subfamily IA + Peptidase M24 + DnaJ domain + PDZ domain + Pyrrolo-quinoline quinone repeat + Type II secretion system protein E + Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain + Anticodon-binding + FAD-binding, type 2, subdomain 1 + Twin-arginine translocation pathway, signal sequence, bacterial/archaeal + FAD dependent oxidoreductase + Cysteine-rich domain + Pyruvate/ketoisovalerate oxidoreductase, catalytic domain + Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) + Cobalamin (vitamin B12)-dependent enzyme, catalytic + ABC transporter type 1, transmembrane domain + Sugar isomerase (SIS) + Translation elongation factor EFTu-like, domain 2 + EF-Hand 1, calcium-binding site + Peptidase S8/S53 domain + Pyruvate carboxyltransferase + HDIG domain + Enolase N-terminal domain-like + Aminoacyl-tRNA synthetase, class II (D/K/N) + LysM domain + Acyl-CoA dehydrogenase, conserved site + Peptidase M20, dimerisation domain + PAS fold + Outer membrane protein/outer membrane enzyme PagP, beta-barrel + Pyridine nucleotide-disulphide oxidoreductase, class-II + Penicillin-binding protein, transpeptidase + Cupin 2, conserved barrel + DNA binding HTH domain, Fis-type + Transposase DDE domain + UvrD/AddA helicase, N-terminal + UspA + Peptidase M23 + DegV + UvrD-like DNA helicase, C-terminal + Thiolase, C-terminal + AAA domain + OmpA-like domain + Methylmalonyl-CoA mutase, alpha/beta chain, catalytic + MacB-like periplasmic core domain + Parallel beta-helix repeat-2 + Endonuclease/exonuclease/phosphatase + Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 + Trimethylamine methyltransferase + 23S rRNA-intervening sequence protein + Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal + Cytidyltransferase-like domain + Biotin/lipoyl attachment + CobQ/CobB/MinD/ParA nucleotide binding domain + Transketolase, C-terminal domain + Carbohydrate kinase, FGGY, N-terminal + Transposase IS3/IS911family + Rhodanese-like domain + FAD-dependent oxidoreductase 2, FAD binding domain + UDP-glucose/GDP-mannose dehydrogenase, N-terminal + RNA polymerase sigma-70 region 4 + Acetyl-CoA carboxylase + Tripartite ATP-independent periplasmic transporter, DctQ component + NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit + Succinyl-CoA synthetase-like, flavodoxin domain + RND efflux pump, membrane fusion protein, barrel-sandwich domain + Aspartate/ornithine carbamoyltransferase + Outer membrane efflux protein + OB-fold nucleic acid binding domain, AA-tRNA synthetase-type + PKD domain + FAD linked oxidase, N-terminal + PHP domain + Transcription regulator FadR/GntR, C-terminal + Periplasmic copper-binding protein NosD, beta helix domain + Toxin-antitoxin system, RelE/ParE toxin family + Mur ligase, C-terminal + HIT-like domain + Resolvase, N-terminal catalytic domain + Protein kinase domain + DNA binding HTH domain, AraC-type + Sodium/solute symporter + D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain + DNA methylase, N-4 cytosine-specific, conserved site + Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain + Oxidoreductase, C-terminal + DHBP synthase RibB-like alpha/beta domain + Elongation factor EFG, domain V-like + O-antigen ligase-related + NUDIX hydrolase, conserved site + Solute-binding family 1 + NiFe hydrogenase-like + Helix-turn-helix, base-excision DNA repair, C-terminal + Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains + RNA polymerase sigma-70 + Electron transfer flavoprotein, alpha/beta-subunit, N-terminal + EAL domain + 2Fe-2S ferredoxin-type iron-sulfur binding domain + ACT domain + Hexapeptide transferase, conserved site + Armadillo-like helical + Transmembrane protein TauE-like + Tr-type G domain, conserved site + Bacterial sugar transferase + Thioredoxin domain + Transposase, IS116/IS110/IS902 + Domain of unknown function DUF11 + MoaB/Mog domain + Carbohydrate kinase, FGGY, C-terminal + Peptidase S9, prolyl oligopeptidase, catalytic domain + Cyclic nucleotide-binding domain + ABC-2 type transporter + DHHA1 domain + Mechanosensitive ion channel MscS + Type II secretion system F domain + FAD/NAD-linked reductase, dimerisation domain + Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain + Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding + Sulfatase, conserved site + PAS fold-4 + GntR, C-terminal + Pseudouridine synthase, RsuA/RluB/C/D/E/F + DapA-like + RND efflux pump, membrane fusion protein + Aminoacyl-tRNA synthetase, class Ic + Tetrapyrrole methylase, subdomain 1 + Clp ATPase, C-terminal + Alcohol dehydrogenase, zinc-type, conserved site + Transposase InsH, N-terminal + Formyl transferase, N-terminal + Sigma-54 interaction domain, ATP-binding site 1 + Transcription regulator AsnC/Lrp, ligand binding domain + HTH ArsR-type DNA-binding domain + Transposase, IS111A/IS1328/IS1533, N-terminal + S-adenosyl-L-methionine-dependent methyltransferase + Molybdopterin dinucleotide-binding domain + Sigma-54 interaction domain, conserved site + Heat shock protein 70 family + SinI-like, DNA-binding domain + Fumarase/histidase, N-terminal + Soluble ligand binding domain + ParB/Sulfiredoxin + PNPase/RNase PH domain + Dihydroprymidine dehydrogenase domain II + Peptidase S24/S26A/S26B/S26C + Transketolase, N-terminal + Histidine phosphatase superfamily + UDP-glucose/GDP-mannose dehydrogenase, dimerisation + Amidohydrolase 3 + Tetrapyrrole methylase + Beta-ketoacyl synthase, N-terminal + 4Fe4S-binding SPASM domain + Polysaccharide biosynthesis protein + HicB-like antitoxin of toxin-antitoxin system + Band 7 domain + Fumarate lyase, N-terminal + Thioesterase domain + Solute-binding protein family 3/N-terminal domain of MltF + GHMP kinase, C-terminal domain + MobA-like NTP transferase + Nucleotidyl transferase AbiEii toxin, Type IV TA system + Enoyl-CoA hydratase/isomerase, conserved site + HEPN domain + HicA mRNA interferase family + ClpA/B family + Polysaccharide biosynthesis protein, C-terminal domain + PEP-utilising enzyme, mobile domain + Phospholipid/glycerol acyltransferase + Chaperonin Cpn60/TCP-1 family + Peptidase M50 + Glyoxalase/fosfomycin resistance/dioxygenase domain + Transposase, mutator type + Tetratricopeptide repeat 1 + Creatinase/Aminopeptidase P/Spt16, N-terminal + NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain + Uracil-DNA glycosylase-like + Enolpyruvate transferase domain + Branched-chain amino acid ATP-binding cassette transporter, C-terminal + Beta-lactamase-related + NADPH-dependent FMN reductase-like + UDP-glucose/GDP-mannose dehydrogenase, C-terminal + Glutamine amidotransferase type 2 domain + Histidine phosphatase superfamily, clade-1 + Nucleoside phosphorylase domain + Fido domain + HAMP domain + Aminotransferases, class-I, pyridoxal-phosphate-binding site + IstB-like ATP-binding protein + FldB/FldC dehydratase alpha/beta subunit + Sigma-54 interaction domain, ATP-binding site 2 + GroEL-like equatorial domain + Exonuclease, phage-type/RecB, C-terminal + Isoprenoid synthase domain + Transglutaminase-like + Phosphopantetheine binding ACP domain + Dinitrogenase iron-molybdenum cofactor biosynthesis + Methyltransferase domain + Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain + Fe-S cluster assembly domain + Amidase signature domain + NAD/GMP synthase + 3-hydroxyacyl-CoA dehydrogenase, NAD binding + Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain + Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding + Sugar transporter, conserved site + Cation/H+ exchanger + Oligopeptide transport permease C-like, N-terminal domain + Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain + ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain + Alpha-D-phosphohexomutase, alpha/beta/alpha domain I + Alcohol dehydrogenase, iron-type + Serine aminopeptidase, S33 + Aspartic peptidase domain + UDP-N-acetylglucosamine 2-epimerase domain + Asparagine synthase + Inosine triphosphate pyrophosphatase-like + Isopropylmalate dehydrogenase-like domain + Glutamine synthetase/guanido kinase, catalytic domain + Phospholipase D-like domain + P-type ATPase + Clp, N-terminal + Thioredoxin, conserved site + N6 adenine-specific DNA methyltransferase, N-terminal domain + Tetrapyrrole methylase, subdomain 2 + HSP20-like chaperone + 2Fe-2S ferredoxin, iron-sulphur binding site + Aconitase/3-isopropylmalate dehydratase, swivel + Pyruvate phosphate dikinase, PEP/pyruvate-binding + SpoVT-AbrB domain + Peptide chain release factor class I/class II + CDP-alcohol phosphatidyltransferase + HTH-like domain + AsnC-type HTH domain + Gcp-like domain + Pterin-binding domain + Cold-shock protein, DNA-binding + Periplasmic binding protein + Restriction modification methylase Eco57I + UbiA prenyltransferase family + Metalloenzyme + Methyl-viologen-reducing hydrogenase, delta subunit + Alanyl-tRNA synthetase, class IIc, N-terminal + Methylthiotransferase, N-terminal + N6 adenine-specific DNA methyltransferase, D21 class + UVR domain + LacI-type HTH domain + MerR-type HTH domain + Regulator of K+ conductance, N-terminal + Alanine racemase, N-terminal + Molybdopterin oxidoreductase, 4Fe-4S domain + Domain of unknown function DUF362 + PAS fold-3 + Peptidase S1C + Ribonucleotide reductase large subunit, C-terminal + Alanine racemase/group IV decarboxylase, C-terminal + NADH:flavin oxidoreductase/NADH oxidase, N-terminal + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site + Peptidase M16, C-terminal + Lamin Tail Domain + NADH:ubiquinone oxidoreductase-like, 20kDa subunit + Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 + HhH-GPD domain + Type II toxin-antitoxin system, antitoxin Phd/YefM + Universal stress protein A + Leucine-rich repeat domain, L domain-like + Metalloprotease TldD/PmbA + Cytidine and deoxycytidylate deaminase domain + Regulator of K+ conductance, C-terminal + Domain of unknown function DUF35, OB-fold, C-terminal + PEP-utilising enzyme, C-terminal + Exoribonuclease, phosphorolytic domain 1 + Alpha-D-phosphohexomutase, alpha/beta/alpha domain III + Chromosomal replication initiator, DnaA C-terminal + Alpha-D-phosphohexomutase, C-terminal + Chaperone DnaJ, C-terminal + Sulfatase-modifying factor enzyme + Schlafen, AAA domain + Carbohydrate/puine kinase, PfkB, conserved site + 3-hydroxyacyl-CoA dehydrogenase, C-terminal + Integration host factor (IHF)-like DNA-binding domain + Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal + Threonyl/alanyl tRNA synthetase, SAD + GHMP kinase N-terminal domain + Ferrous iron transporter FeoA domain + MarR-type HTH domain + Metallopeptidase, catalytic domain + Histidine biosynthesis + Peptide chain release factor + Dehydrogenase, E1 component + UDP-glucose/GDP-mannose dehydrogenase + Methionyl/Leucyl tRNA synthetase + Ferric-uptake regulator + tRNA/rRNA methyltransferase, SpoU type + FAD-linked oxidase, C-terminal + Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase + Domain of unknown function DUF4143 + Methyl-accepting chemotaxis protein (MCP) signalling domain + Peptidase M48 + Pyruvate:ferredoxin oxidoreductase, core domain II + Plasmid maintenance toxin/Cell growth inhibitor + Histone deacetylase domain + Bacterial DNA polymerase III, alpha subunit + TaqI-like C-terminal specificity domain + Heat shock protein 70, conserved site + NodB homology domain + Alpha-D-phosphohexomutase, alpha/beta/alpha domain II + Tail specific protease + ROK family + Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal + Inorganic polyphosphate/ATP-NAD kinase, domain 1 + CAAX amino terminal protease + Aminotransferase class IV + Reverse transcriptase domain + FAD-linked oxidoreductase-like + Translation elongation factor EF1B/ribosomal protein S6 + DNA topoisomerase, type IIA, subunit A/C-terminal + Fumarate lyase family + Transposase, IS66 + Coenzyme A transferase family I + APOBEC/CMP deaminase, zinc-binding + Glycoside hydrolase-type carbohydrate-binding + Glutamine synthetase, catalytic domain + NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain + Endoribonuclease L-PSP/chorismate mutase-like + ATPase, BadF/BadG/BcrA/BcrD type + MaoC-like domain + Methylthiotransferase, conserved site + 2-oxoacid dehydrogenase acyltransferase, catalytic domain + K Homology domain, type 1 + Oxidoreductase FAD/NAD(P)-binding + SNF2-related, N-terminal domain + Nucleoside transporter/FeoB GTPase, Gate domain + Histone-like DNA-binding protein + Probable peptidoglycan glycosyltransferase FtsW/RodA + YrdC-like domain + Signal recognition particle, SRP54 subunit, GTPase domain + Pyruvate formate lyase domain + Methylglyoxal synthase-like domain + Mur ligase, N-terminal catalytic domain + DNA-binding recombinase domain + RadC-like JAB domain + Domain of unknown function DUF262 + Calcineurin-like phosphoesterase domain, lpxH type + Multi antimicrobial extrusion protein + Thioredoxin-like fold + Tubulin/FtsZ, GTPase domain + Translation elongation factor EFG/EF2, domain IV + Beta-ketoacyl synthase, C-terminal + Alpha-isopropylmalate/homocitrate synthase, conserved site + PPM-type phosphatase domain + NUDIX hydrolase + Phosphoglycolate phosphatase, domain 2 + Phenylalanyl-tRNA synthetase, B3/B4 + DNA helicase, DnaB-like, C-terminal + Dihydroxy-acid/6-phosphogluconate dehydratase + Alpha crystallin/Hsp20 domain + Peptidase S8, subtilisin-related + Protein-export membrane protein SecD/SecF, archaeal and bacterial + Polyprenyl synthetase + Glycosyl transferase, family 51 + FlgD Ig-like domain + Flavin reductase like domain + mRNA interferase PemK-like + Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain + ATP synthase subunit alpha-like domain + Polysaccharide pyruvyl transferase + Vanillyl-alcohol oxidase, C-terminal subdomain 2 + Peptidase M16, N-terminal + Rubrerythrin + Hemolysin-type calcium-binding conserved site + Metalloprotease TldD/PmbA, N-terminal domain + Exoribonuclease, phosphorolytic domain 2 + Cobalamin (vitamin B12)-binding module, cap domain + Transcription regulator PadR, N-terminal + Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 + DNA topoisomerase, type IIA + Zinc finger, CHC2-type + 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal + Outer membrane protein, bacterial + Creatinase, N-terminal + Glycosyl hydrolase, family 13, catalytic domain + Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain + Glycerol-3-phosphate acyltransferase, PlsY + MotA/TolQ/ExbB proton channel + Maltose transport system permease protein MalF N-terminal domain + Peptidase S16, Lon proteolytic domain + Phosphoglycerate kinase, N-terminal + Glutathione S-transferase, N-terminal + L,D-transpeptidase catalytic domain + STAS domain + Asp/Glu/hydantoin racemase + Aconitase A/isopropylmalate dehydratase small subunit, swivel domain + Semialdehyde dehydrogenase, NAD-binding + Transglycosylase SLT domain 1 + Restriction endonuclease type IV, Mrr + Putative regulatory protein, FmdB, Zinc ribbon domain + START-like domain + Phospholipid methyltransferase + Restriction endonuclease, type I, HsdR, N-terminal + Protein of unknown function DUF86 + RNA polymerase sigma-70 region 1.2 + HNH endonuclease + Glycosyl transferase, family 4 + Histidine triad (HIT) protein + DeoC/FbaB/ lacD aldolase + Glycoside hydrolase 38/57, N-terminal domain + Amino acid exporter protein, LeuE-type + Holliday junction DNA helicase ruvB, N-terminal + ATPase, alpha/beta subunit, nucleotide-binding domain, active site + Gingipain + Clp protease proteolytic subunit /Translocation-enhancing protein TepA + Phosphoglycerate kinase + Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal + Dihydroorotate dehydrogenase domain + DDH domain + Class II aldolase/adducin N-terminal + Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD + 2-oxo acid dehydrogenase, lipoyl-binding site + Nickel-dependent hydrogenase, large subunit + CARDB domain + Glycine cleavage T-protein-like, N-terminal + Fumarylacetoacetase, C-terminal-related + RNA polymerase sigma-70 region 3 + Nitronate monooxygenase + Cys/Met metabolism, pyridoxal phosphate-dependent enzyme + ATPase, F1/V1 complex, beta/alpha subunit, C-terminal + Phosphofructokinase domain + Semialdehyde dehydrogenase, dimerisation domain + Aminoglycoside phosphotransferase + Ribbon-helix-helix protein, CopG + Alpha-D-phosphohexomutase superfamily + Methyltransferase FkbM + Fumarate lyase, conserved site + Aconitase family, 4Fe-4S cluster binding site + Tubulin/FtsZ, 2-layer sandwich domain + Peptidase S8, subtilisin, Ser-active site + Adenylyl cyclase class-3/4/guanylyl cyclase + DNA topoisomerase, type IA, central + NYN domain, limkain-b1-type + Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain + Poly A polymerase, head domain + Mandelate racemase/muconate lactonizing enzyme, N-terminal domain + DNA topoisomerase, type IIA, central domain + TGS + TRAP transporter permease protein + RecF/RecN/SMC, N-terminal + RmlD-like substrate binding domain + P-type ATPase, cytoplasmic domain N + Peptidase S54, rhomboid domain + Cyclophilin-like domain + Inositol monophosphatase-like + SNARE associated Golgi protein + Domain of unknown function DUF1080 + Zn-dependent metallo-hydrolase, RNA specificity domain + FAD-binding domain + GroEL-like apical domain + Ankyrin repeat-containing domain + ADC synthase + DnaJ domain, conserved site + tRNA-guanine(15) transglycosylase-like + Domain of unknown function DUF4976 + DNA-directed DNA polymerase, family A, palm domain + Isochorismatase-like + Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain + Serine/threonine-protein kinase, active site + AhpD-like + Putative deacetylase LmbE-like domain + DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat + DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal + Exonuclease, RNase T/DNA polymerase III + Carbohydrate kinase, FGGY, conserved site + Aspartyl/Asparaginyl-tRNA synthetase, class IIb + ATP-cone domain + TatD family + Patatin-like phospholipase domain + Protein of unknown function DUF2283 + Aminotransferase class-V, pyridoxal-phosphate binding site + Homing endonuclease + FeoB-type guanine nucleotide-binding (G) domain + Phenylalanyl-tRNA synthetase + Enolase, C-terminal TIM barrel domain + SecA DEAD-like, N-terminal + Penicillin-binding protein, dimerisation domain + tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal + Methylthiotransferase + Glutamyl/glutaminyl-tRNA synthetase + PUA domain + GroES chaperonin family + Acylphosphatase-like domain + DNA-directed RNA polymerase, subunit 2, domain 6 + Hedgehog signalling/DD-peptidase zinc-binding domain + Peptidase M24, methionine aminopeptidase + Glycoside hydrolase, family 3, N-terminal + ClpA/B, conserved site 1 + TRAM domain + Heat shock protein 70kD, peptide-binding domain + K Homology domain, type 2 + ABC-2 family transporter protein + DNA topoisomerase, type IIA, subunit B + Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain + Glycosyl transferase, family 3 + Cellulosome anchoring protein, cohesin domain + Pyrophosphate-energised proton pump + Methylthioribose-1-phosphate isomerase-like, N-terminal domain + Tetratricopeptide repeat 2 + RNA polymerase Rpb1, domain 5 + Cation efflux protein + LarA-like, N-terminal + Crp-type HTH domain + Primosome PriB/single-strand DNA-binding + 50S ribosomal protein L30e-like + ArgJ-like domain + tRNA-binding domain + Arginine repressor C-terminal-like domain + Protein-export membrane protein SecD/SecF, bacterial + Haemolysin-type calcium-binding repeat + Glutamine synthetase, beta-Grasp domain + Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal + PEP-CTERM protein-sorting domain + Transport-associated OB, type 2 + DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta + Chromosomal replication initiator protein DnaA + Methylenetetrahydrofolate reductase + Methylmalonyl-CoA mutase, C-terminal + NAD kinase + Thioredoxin + Polyprenyl synthetase, conserved site + Signal recognition particle, SRP54 subunit, helical bundle + ATP-dependent 6-phosphofructokinase + 3'-5' exonuclease domain + V-ATPase proteolipid subunit C-like domain + Dihydrofolate reductase-like domain + Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain + P-type ATPase, phosphorylation site + Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain + Protein of unknown function DUF4445 + SecY/SEC61-alpha family + PLC-like phosphodiesterase, TIM beta/alpha-barrel domain + Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead + FKBP-type peptidyl-prolyl cis-trans isomerase domain + Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal + Alpha-D-phosphohexomutase, conserved site + DAHP synthetase I/KDSA + Uncharacterised protein family UPF0047 + D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 + Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding + Thiamine pyrophosphate enzyme, central domain + KOW + Nucleotide sugar epimerase + ParB/RepB/Spo0J partition protein family + Transmembrane protein TqsA-like + ATPase, AAA-3 + 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III + General secretory system II, protein E, N-terminal + Flavoprotein + DNA mismatch repair protein MutS, C-terminal + Decaprenyl diphosphate synthase-like + Protein of unknown function DUF1559 + ABC-2 transporter + Peptidase M41 + 6-phosphogluconate dehydrogenase, NADP-binding + Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain + Cell shape determining protein MreB + Ribose-phosphate diphosphokinase + Peptidoglycan binding-like + Enolase + ATP-citrate lyase/succinyl-CoA ligase + Biopolymer transport protein ExbD/TolR + TsaA-like domain + Uncharacterised protein family UPF0758, conserved site + tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain + Polysaccharide biosynthesis protein, CapD-like domain + Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like + NusB/RsmB/TIM44 + Carbamoyl-phosphate synthase large subunit, CPSase domain + DNA recombination and repair protein RecA + Aspartate carbamoyltransferase + RNA polymerase Rpb1, domain 1 + Glyceraldehyde/Erythrose phosphate dehydrogenase family + Pseudouridine synthase, RluC/RluD, conserved site + Prolipoprotein diacylglyceryl transferase + ABC transporter periplasmic binding domain + DALR anticodon binding + HpcH/HpaI aldolase/citrate lyase domain + Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain + NusG, N-terminal + Oxidoreductase, FAD-binding domain + Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain + Adenosylhomocysteinase-like + Protein of unknown function DUF433 + Peptide deformylase + TRAP transporter solute receptor, TAXI family + ATPase, AAA-type, conserved site + DNA topoisomerase, type IIA, subunit B, domain 2 + Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 + DNA recombination-mediator protein A + 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain + Helicase HerA, central domain + Sodium/calcium exchanger membrane region + NIF system FeS cluster assembly, NifU, N-terminal + Cold-shock conserved site + Zinc-ribbon domain + Aldehyde dehydrogenase, cysteine active site + Phosphatidic acid phosphatase type 2/haloperoxidase + PhoU domain + ADP-ribosylation/Crystallin J1 + Transcriptional regulator TACO1-like + Protein kinase, ATP binding site + NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site + Ribosomal RNA small subunit methyltransferase H + Ribosomal protein L5 domain + [2Fe-2S]-binding + MmgE/PrpD + tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related + Transcription elongation factor, GreA/GreB, C-terminal + YbaK/aminoacyl-tRNA synthetase-associated domain + Type IIA DNA topoisomerase subunit A, alpha-helical domain + Adenylosuccinate synthetase + tRNA synthetases class I, catalytic domain + Orn/DAP/Arg decarboxylase 2, N-terminal + Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain + Predicted permease DUF318 + Single-stranded DNA-binding protein + Glycine cleavage T-protein, C-terminal barrel domain + MIP18 family-like + Sporulation-related domain + Glycine cleavage system P protein + Bacterial general secretion pathway protein G-type pilin + Glycoside hydrolase, family 29 + Magnesium chelatase ChlI domain + SUF system FeS cluster assembly, SufBD + Peptidoglycan biosynthesis protein MurJ + PBP domain + Triosephosphate isomerase + Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic + DNA-directed RNA polymerase, RpoA/D/Rpb3-type + Aldehyde dehydrogenase, glutamic acid active site + Transcription regulator IclR, N-terminal + Electron transfer flavoprotein, alpha subunit, C-terminal + DNA primase, catalytic core, N-terminal + Toll/interleukin-1 receptor homology (TIR) domain + Domain of unknown function DUF21 + GrpE nucleotide exchange factor + Forkhead-associated (FHA) domain + Peptidase S26A, signal peptidase I + YjgF/YER057c/UK114 family + Prismane-like, alpha/beta-sandwich + Glutamate synthase domain + RNA polymerase, alpha subunit, C-terminal + ABC transporter, FecCD-like + Methyltransferase small domain + Arginyl-tRNA synthetase, catalytic core domain + TonB, C-terminal + PurE domain + CobW/HypB/UreG, nucleotide-binding domain + NAD-dependent DNA ligase, adenylation + ATP-dependent Clp protease proteolytic subunit + UmuC domain + FtsK domain + B3/B4 tRNA-binding domain + Protein translocase subunit SecA + Gingipain, N-terminal + Tetrahydrofolate dehydrogenase/cyclohydrolase + Protein-export membrane protein SecD/SecF/SecDF, conserved site + ABC-transporter extension domain + Carboxymuconolactone decarboxylase-like + HTH domain AraC-type, conserved site + Zinc finger, RING/FYVE/PHD-type + Chorismate-utilising enzyme, C-terminal + Glycosyl transferase, family 28, C-terminal + Histone deacetylase superfamily + DNA polymerase, helix-hairpin-helix motif + Histidinol dehydrogenase + Peptidase M28 + Ribosomal RNA adenine methyltransferase KsgA/Erm + Ribosomal protein S2 + Quinolinate phosphoribosyl transferase, N-terminal + Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site + Adenylate kinase/UMP-CMP kinase + ATP-dependent (S)-NAD(P)H-hydrate dehydratase + Transcriptional regulator TACO1-like, domain 3 + N-acetylglucosaminyl phosphatidylinositol deacetylase-related + NfeD-like, C-terminal domain + Protein of unknown function DUF112, transmembrane + Peptidyl-prolyl cis-trans isomerase, PpiC-type + Methylmalonyl-CoA mutase, alpha chain, catalytic + Transcription regulator IclR, C-terminal + Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal + Transcription regulator HTH, AraC- type + Ribonuclease HII/HIII domain + Lon, substrate-binding domain + Pyridoxamine 5'-phosphate oxidase, putative + Type II/III secretion system + tRNA dimethylallyltransferase + Ribulose-phosphate 3-epimerase-like + Chaperonin Cpn60 + D12 class N6 adenine-specific DNA methyltransferase + Protein of unknown function DUF45 + Transaldolase/Fructose-6-phosphate aldolase + Flagellar basal body rod protein, N-terminal + Initiation factor 2B-related + Peptidase M42 + Mannoside phosphorylase + Ribose-phosphate pyrophosphokinase, N-terminal domain + C-5 cytosine methyltransferase + Ribosomal protein L4 domain + Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain + YjeF N-terminal domain + Beta-ketoacyl synthase, active site + Membrane insertase OXA1/ALB3/YidC + DJ-1/PfpI + Ferrous iron transport protein B, C-terminal + Enolase, N-terminal + ClpA/B, conserved site 2 + Transcription regulator Rrf2-type + RadC protein + DNA gyrase B subunit, C-terminal + YqgF/RNase H-like domain + Heat shock protein 70kD, C-terminal domain + Sirtuin family + CTP synthase, N-terminal + Methioninyl-tRNA synthetase core domain + Chromosomal replication control, initiator DnaA-like + E3-binding domain + Protein of unknown function DUF5320 + Phosphate acetyl/butaryl transferase + Fructose-bisphosphate aldolase, class-II + Ribosomal protein L6, alpha-beta domain + Nickel-dependent hydrogenase, large subunit, nickel binding site + SEC-C motif + THIF-type NAD/FAD binding fold + Quinolinate phosphoribosyl transferase, C-terminal + Zinc finger, DksA/TraR C4-type + GrpE nucleotide exchange factor, head + Proteasome assembly chaperone 2 + Cation transporter + Homocysteine-binding domain + Sec-independent protein translocase protein TatA/B/E + Ribosomal protein L13 + Gamma-glutamyltranspeptidase + Amino acid/polyamine transporter I + CinA, C-terminal + Transporter-associated domain + DNA polymerase III, beta chain, central + Amino acid ABC transporter, permease protein, 3-TM domain + RNA polymerase Rpb2, domain 2 + DNA polymerase A + Glutamate/acetylglutamate kinase + Protein of unknown function DUF72 + PilZ domain + MEMO1 family + Type I restriction enzyme R protein, N-terminal domain + tRNA-splicing ligase, RtcB + Acylphosphatase, conserved site + Peptidase S8, subtilisin, Asp-active site + Pentapeptide repeat + Transposase IS204/IS1001/IS1096/IS1165, DDE domain + Biotin carboxylase-like, N-terminal domain + 4Fe-4S domain + Translation elongation factor EFTs/EF1B, dimerisation + Sugar-phosphate isomerase, RpiB/LacA/LacB family + Pyruvate kinase, C-terminal + Stomatin family + DNA helicase, DnaB-like, N-terminal + ATPase, dynein-related, AAA domain + Formate-tetrahydrofolate ligase, FTHFS + GxxExxY protein + Ribonuclease III domain + Permease LptG/LptF-related + 4'-phosphopantetheinyl transferase superfamily + Rnf-Nqr subunit, membrane protein + SGNH hydrolase-type esterase domain + Peptidyl-tRNA hydrolase + Ribosomal protein L4/L1e + RelA/SpoT + Fatty acid synthesis PlsX protein + Ham1-like protein + Recombinase, conserved site + ATP-dependent DNA helicase RecG, C-terminal domain + Protein of unknown function DUF3795 + Molybdopterin dehydrogenase, FAD-binding + Ribosomal protein L1/ribosomal biogenesis protein + Peptidase M14, carboxypeptidase A + Threonine-tRNA ligase, class IIa + SH3-like domain, bacterial-type + Polysaccharide chain length determinant N-terminal domain + Aromatic amino acid beta-eliminating lyase/threonine aldolase + Acylneuraminate cytidylyltransferase + Kelch-type beta propeller + Orotidine 5'-phosphate decarboxylase domain + Leucine-tRNA ligase + Cytochrome c oxidase-like, subunit I domain + NAD(+) synthetase + Rieske [2Fe-2S] iron-sulphur domain + Argininosuccinate synthase + Hydroxylamine reductase/Ni-containing CO dehydrogenase + NTP pyrophosphohydrolase MazG, putative catalytic core + SAICAR synthetase/ADE2, N-terminal + 5'-3' exonuclease, alpha-helical arch, N-terminal + SecA Wing/Scaffold + Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain + ATP synthase, F1 complex, gamma subunit + Nucleoside diphosphate kinase-like domain + Staphylococcal nuclease (SNase-like), OB-fold + ThiamineS/Molybdopterin converting factor subunit 1 + GrpE nucleotide exchange factor, coiled-coil + Glycerophosphodiester phosphodiesterase domain + Ribosomal protein L18e/L15P + Translation elongation factor EFTu/EF1A, C-terminal + IMP dehydrogenase/GMP reductase + dTDP-4-dehydrorhamnose 3,5-epimerase-related + Ribosomal protein S9 + CarD-like/TRCF domain + Glutaredoxin + Tryptophan-tRNA ligase + HD/PDEase domain + Trigger factor, C-terminal + SCP2 sterol-binding domain + Ribosomal protein L14P + Membrane transport protein MMPL domain + Tyrosine-tRNA ligase + DNA topoisomerase, type IA, zn finger + tRNA methyltransferase TRMD/TRM10-type domain + LVIVD + CoA enzyme activase + Peptidase S8, subtilisin, His-active site + Asn/Gln amidotransferase + Glutamate/phenylalanine/leucine/valine dehydrogenase + OsmC/Ohr family + Ribosomal protein S8 + DeoR-type HTH domain + Iron dependent repressor, metal binding and dimerisation domain + Peptidase S49 + Ribosomal protein S30Ae/sigma 54 modulation protein + Prepilin type IV endopeptidase, peptidase domain + Peptidase HybD-like domain + Cell division protein FtsZ, C-terminal + Creatininase-like domain + Ribosome recycling factor domain + Chorismate synthase + Biotin carboxylase, C-terminal + Ribosomal protein S13 + Citrate transporter-like domain + Crossover junction endodeoxyribonuclease RuvC + Translation initiation factor IF- 2, domain 3 + Ribosomal protein S2, bacteria/mitochondria/plastid + Bacterial surface antigen (D15) + Cytochrome C biogenesis protein, transmembrane domain + Domain of unknown function DUF58 + Ribosomal protein L10e/L16 + Alanine-tRNA ligase, class IIc + ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR + Cation efflux protein, cytoplasmic domain + Flagellar basal-body/hook protein, C-terminal domain + Transcription elongation factor, GreA/GreB, N-terminal + NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H + Molybdopterin oxidoreductase, prokaryotic, conserved site + ComEC/Rec2-related protein + PEP-utilising enzyme, active site + Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain + Formyl transferase, C-terminal + Heparinase II/III-like + Phosphoenolpyruvate carboxykinase, C-terminal + Ureohydrolase + DNA-binding HTH domain, TetR-type, conserved site + Trigger factor, ribosome-binding, bacterial + TerB-like + DNA-directed RNA polymerase, insert domain + Peptidase M3A/M3B catalytic domain + Phosphoadenosine phosphosulphate reductase + LOG family + Phosphotyrosine protein phosphatase I superfamily + Pyridine nucleotide-disulphide oxidoreductase, class I, active site + Glycosyl transferase family 3, N-terminal domain + Polyketide cyclase SnoaL-like domain + AMP-dependent ligase, C-terminal + Arginine-tRNA ligase + DNA polymerase III, beta chain, C-terminal + Riboflavin kinase domain + Ribosomal protein L5, C-terminal + Isocitrate/isopropylmalate dehydrogenase, conserved site + Serine/threonine dehydratase, pyridoxal-phosphate-binding site + DNA polymerase, Y-family, little finger domain + Aldo/keto reductase + Ferritin/DPS protein domain + NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding + Ribosomal protein L11, N-terminal + ABC transporter substrate-binding protein PnrA-like + Ribosomal protein L25/L23 + Uncharacterised conserved protein UCP033563 + Metalloprotease catalytic domain, predicted + Ribosomal protein S11 + Putative esterase + Quinolinate synthetase A + Signal transduction histidine kinase, phosphotransfer (Hpt) domain + Phosphotransferase/anion transporter + Integrase, N-terminal zinc-binding domain-like + Ribosomal protein S7 domain + Thiolase + Guanylate kinase/L-type calcium channel beta subunit + Transcription factor NusA, N-terminal + Valine-tRNA ligase + ATP synthase, F0 complex, subunit A + Sialidases + RNA polymerase Rpb1, domain 3 + Dephospho-CoA kinase + MoeA, N-terminal and linker domain + SsrA-binding protein + RNA polymerase, beta subunit, protrusion + Ferrodoxin-fold anticodon-binding domain + Arginyl tRNA synthetase N-terminal domain + Ribosomal protein L11, C-terminal + Acyl transferase + Biotin-binding site + Ribosomal protein S12/S23 + ABC/ECF transporter, transmembrane component + Recombinase zinc beta ribbon domain + Ornithine/DAP/Arg decarboxylase + SLC26A/SulP transporter domain + Ribosomal protein L10P + Ribosomal protein S17/S11 + Translation elongation factor, KOW-like + Ribosomal protein S15 + Ribokinase/fructokinase + Helix-turn-helix, type 11 + Inosine/uridine-preferring nucleoside hydrolase domain + D-alanine--D-alanine ligase, C-terminal + Oxidoreductase, molybdopterin-binding domain + DNA polymerase III, beta chain, N-terminal + MoaA/nifB/pqqE, iron-sulphur binding, conserved site + ATP-dependent RNA helicase DEAD-box, conserved site + Survival protein SurE-like phosphatase/nucleotidase + ArgE/DapE/ACY1/CPG2/YscS, conserved site + Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal + Ornithine/putrescine carbamoyltransferase + BRCT domain + Aminotransferase, class-II, pyridoxal-phosphate binding site + Domain of unknown function DUF89 + MgsA AAA+ ATPase C-terminal + Endoribonuclease YbeY + Integrase, DNA-binding domain + KH domain, NusA-like + Thiolase, conserved site + N-acetylmuramoyl-L-alanine amidase, catalytic domain + Peptidase M1, membrane alanine aminopeptidase, N-terminal + NADH-quinone oxidoreductase, subunit D + Domain of unknown function DUF933 + DNA recombination and repair protein RecA, C-terminal + PTS EIIA type-2 domain + dUTPase-like + IrrE N-terminal-like domain + UbiD decarboxylyase family + Bacterial bifunctional deaminase-reductase, C-terminal + Chemotaxis methyl-accepting receptor + Aliphatic acid kinase, short-chain + HNH nuclease + Small protein B + ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast + Phenylacetic acid degradation-related domain + RNA-binding domain, S1, IF1 type + 30s ribosomal protein S13, C-terminal + Ribosomal protein L2, C-terminal + PEP-utilising enzyme, conserved site + Alcohol dehydrogenase, iron-type, conserved site + Glycosyl hydrolase family 38, C-terminal + RNA polymerase, alpha subunit + Ribosomal protein L22/L17 + Heavy metal-associated domain, HMA + Ribosomal protein S5, C-terminal + Ribosomal protein L5, N-terminal + CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel + SecA preprotein, cross-linking domain + Creatininase/formamide hydrolase + FtsK gamma domain + DNA topoisomerase, type IA, central region, subdomain 2 + Ammonium transporter AmtB-like domain + Homoserine dehydrogenase, catalytic + Putative zinc-finger + Ribosomal protein L17 + Cupredoxin + 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK + tRNA-dihydrouridine synthase + Orn/DAP/Arg decarboxylase 2, C-terminal + CheW-like domain + Kae1/TsaD family + LytTR DNA-binding domain + DnaA N-terminal domain + Ribosomal protein L7/L12, C-terminal + 5'-3' exonuclease, C-terminal domain + NIF system FeS cluster assembly, NifU, C-terminal + LexA repressor, DNA-binding domain + Diaminopimelate epimerase, DapF + UvrC family homology region + Ribosomal protein S3, C-terminal + DNA polymerase III, alpha subunit + Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal + Isoleucine-tRNA ligase + MraZ domain + NADH:ubiquinone oxidoreductase + DNA topoisomerase, type IIA, conserved site + GTP cyclohydrolase II + RNA recognition motif domain + Malic enzyme, N-terminal domain + AICARFT/IMPCHase bienzyme + Pyrroline-5-carboxylate reductase, catalytic, N-terminal + Pyrrolo-quinoline quinone-like domain + GTP1/OBG domain + Ribosomal protein L19 + DNA/pantothenate metabolism flavoprotein, C-terminal + Pseudouridine synthase I, TruA, alpha/beta domain + Serine-tRNA synthetase, type1, N-terminal + Ribosomal Proteins L2, RNA binding domain + F-type ATP synthase subunit B-like, membrane domain + Amine oxidase + Aminotransferase, class IV, conserved site + Ribosomal protein S2, conserved site + Sulphur transport domain + Ribosomal protein S6 + Cysteinyl-tRNA synthetase/mycothiol ligase + Ribosomal protein S10 domain + Thiolase, active site + Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ + Ketopantoate hydroxymethyltransferase + GspD/PilQ family + tRNA synthetase, B5-domain + rRNA adenine dimethylase-like + Acetyl-coenzyme A synthetase, N-terminal domain + AICAR transformylase domain + WD40 repeat + UbiC transcription regulator-associated + Ribosomal protein L18 + TGS-like domain + Glycosyl transferase, family 9 + Citrate synthase + Recombination protein O, RecO + FAD synthetase + Pyruvate kinase, barrel + Elongation factor P, C-terminal + GMP synthase, C-terminal + Membrane insertase YidC/Oxa1, C-terminal + Ribosomal protein S4/S9, N-terminal + Pseudouridine synthase II, N-terminal + Translation elongation factor P/YeiP, central + Malic enzyme, NAD-binding + Ribosomal protein S19, superfamily + Arginine biosynthesis protein ArgJ + Putative pre-16S rRNA nuclease + Heat shock protein DnaJ, cysteine-rich domain + Ribosomal protein S5, N-terminal + Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain + Adenylate kinase, conserved site + ABC transporter, TroCD-like + NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site + Hedgehog/Intein (Hint) domain + Thiolase, acyl-enzyme intermediate active site + Ribosomal protein S19/S15 + Prephenate dehydrogenase + Ribosomal protein S20 + NHL repeat + Phenylalanine-tRNA ligase, class II, N-terminal + Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain + Ornithine cyclodeaminase/mu-crystallin + Dihydrodipicolinate reductase, N-terminal + 2,3-bisphosphoglycerate-independent phosphoglycerate mutase + SecY conserved site + Ribosomal protein L20 C-terminal domain + Folylpolyglutamate synthetase, conserved site + Phosphopantetheine attachment site + Peptidase A31 family + Hydrolyase LeuD/HacB/DmdB + Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site + Riboflavin kinase domain, bacterial/eukaryotic + Translation initiation factor 3, C-terminal + Ribosomal protein L20 + Peptidase A8, signal peptidase II + Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain + Cytochrome c oxidase subunit I + Phosphoenolpyruvate carboxykinase, N-terminal + Mg chelatase-related protein, C-terminal domain + Leucyl-tRNA synthetase, editing domain + Domain of unknown function DUF4162 + BFD-like [2Fe-2S]-binding domain + ATP phosphoribosyltransferase, catalytic domain + Phosphate transporter + tRNA threonylcarbamoyl adenosine modification protein TsaE + Bacterial lipid A biosynthesis acyltransferase + 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type + RNA polymerase Rpb2, domain 3 + Uncharacterised protein family UPF0102 + S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA + ATP-grasp fold, succinyl-CoA synthetase-type + Argininosuccinate synthetase, catalytic/multimerisation domain body + Aquaporin-like + Ribosomal protein L21-like + 3-dehydroquinate synthase domain + S-adenosyl-L-homocysteine hydrolase, NAD binding domain + ISXO2-like transposase domain + Rho termination factor, N-terminal + Ribosomal protein L2, domain 3 + Capsule synthesis protein, CapA + Pseudouridine synthase I, TruA, C-terminal + MoeA, C-terminal, domain IV + Ribosomal protein S16 domain + RlpA-like protein, double-psi beta-barrel domain + CO dehydrogenase flavoprotein, C-terminal + Deoxyribonuclease, TatD-related, conserved site + Glycine cleavage system H-protein/Simiate + Polyribonucleotide nucleotidyltransferase, RNA-binding domain + Ribosomal protein L3 + P22 tailspike C-terminal domain-like + PEGA + Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain + Nucleoid-associated protein YbaB/EbfC family + Protein-L-isoaspartate(D-aspartate) O-methyltransferase + Ribosomal protein L16 + Ribosomal protein L24 + Dihydroorotase, conserved site + Ribosomal protein L29/L36 + Translation initiation factor 3 + S-adenosylmethionine synthetase, C-terminal + Endolytic murein transglycosylase + Zinc finger, FPG/IleRS-type + HAD-superfamily hydrolase, subfamily IIB + Double-stranded RNA-binding domain + Double zinc ribbon + Ribosomal protein S10 + Ribonucleoside-triphosphate reductase, anaerobic + Serine-tRNA ligase, type1 + Ribosomal protein L13, bacterial-type + Ribosomal protein S3, bacterial + Peptidase M24A, methionine aminopeptidase, subfamily 1 + Ribosomal protein L7/L12, oligomerisation + Acetohydroxy acid isomeroreductase, NADPH-binding domain + Citrate synthase-like, large alpha subdomain + Cytochrome c assembly protein + DNA methylase, C-5 cytosine-specific, active site + Ribosomal protein L9, C-terminal + ATP-NAD kinase, PpnK-type, all-beta + Lysyl-tRNA synthetase, class II, C-terminal + Glycoside hydrolase, family 5 + TPP-binding enzyme, conserved site + DeoR C-terminal sensor domain + Undecaprenyl-diphosphatase UppP + Phosphoenolpyruvate carboxykinase, ATP-utilising + GspF/PilC family + Amidohydrolase + Molybdenum cofactor biosynthesis, conserved site + Shikimate kinase/gluconokinase + Nucleoside diphosphate kinase + SsuA/THI5-like + AMMECR1 domain + Protein of unknown function DUF4258 + 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB + Type IV pilus assembly protein PilM + POTRA domain, BamA/TamA-like + Lumazine/riboflavin synthase + Ribosomal protein S15, bacterial-type + Transcription antitermination protein, NusG + Anthranilate synthase component I-like + DNA polymerase III, beta chain + Kynurenine formamidase + S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain + Enolase, conserved site + Pseudouridine synthase, RsuA/RluB/E/F, conserved site + AAA+ ATPase domain + 4-hydroxy-3-methylbut-2-enyl diphosphate reductase + Ribosomal RNA adenine methylase transferase, conserved site + Cytidylate kinase domain + NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal + S-adenosylmethionine synthetase, conserved site + RNA polymerase Rpb2, domain 7 + Aspartate/homoserine dehydrogenase, NAD-binding + Ribosomal protein S16 + Macro domain + Translation initiation factor IF-2, N-terminal + Rho termination factor, RNA-binding domain + Proline-tRNA ligase, class IIa + Putative zinc- or iron-chelating domain containing protein + Modification methylase HemK + Dihydroorotate dehydrogenase, conserved site + Glycosyl hydrolases family 2, sugar binding domain + Renal dipeptidase family + Ribosomal protein L27 + Alanine racemase + Adenine nucleotide alpha hydrolase-like domains + Histone-like DNA-binding protein, conserved site + SAF domain + Regulatory factor, effector binding domain + Flagellin, D0/D1 domain + Pantoate-beta-alanine ligase + Phosphomethylpyrimidine synthase + Thymidylate synthase/dCMP hydroxymethylase domain + AMMECR1, N-terminal + Domain of unknown function DUF559 + Glycine radical domain + Glycoside hydrolase family 38, N-terminal domain + Allosteric substrate binding domain + Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase + Translation initiation factor 3, N-terminal + DNA helicase, Holliday junction RuvA type, domain I, bacterial + D-Tyr tRNAtyr deacylase-like domain + Schiff base-forming aldolase, active site + Phosphopantetheine adenylyltransferase + Peptidase M17, leucyl aminopeptidase, C-terminal + YdiL-like domain + Ribosomal protein L9, N-terminal + Transposase, IS801/IS1294 + Type III pantothenate kinase + 6-pyruvoyl tetrahydropterin synthase/QueD family protein + Preprotein translocase SecG subunit + Ribosomal protein L1, 3-layer alpha/beta-sandwich + 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate + Glutathione S-transferase, C-terminal + Ribonuclease E inhibitor RraA/RraA-like protein + Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal + Protein of unknown function DUF3160 + Thymidylate synthase ThyX + Peroxiredoxin, C-terminal + D-aminoacyl-tRNA deacylase DTD + Di-trans-poly-cis-decaprenylcistransferase-like, conserved site + Acyl carrier protein (ACP) + DNA-directed RNA polymerase, beta subunit, external 1 domain + Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal + DNA mismatch repair protein MutS, core + Transcription regulator HTH, AsnC-type, conserved site + Formamidopyrimidine-DNA glycosylase, catalytic domain + DNA topoisomerase, type IA, active site + Ribosomal protein L6, bacterial-type + Thiamine phosphate synthase/TenI + WYL domain + Solute-binding protein family 5, conserved site + Prephenate dehydratase + Ribosomal protein L15, bacterial-type + Imidazoleglycerol-phosphate dehydratase + SHS2 domain inserted in FtsA + Smr domain + Helix-hairpin-helix motif + NADH:ubiquinone oxidoreductase, 30kDa subunit + DTXR-type HTH domain + Anthranilate synthase component I, N-terminal + Colicin V production, CvpA + GATS-like ACT domain + NAD-dependent DNA ligase, OB-fold + DNA helicase, Holliday junction RuvB type, C-terminal + Translation initiation factor IF-1 + Prepilin-type processing-associated H-X9-DG domain + Polyphosphate kinase-2-related + TSP type-3 repeat + Carbohydrate-binding domain, family 9 + Flagellar motor switch protein FliG, alpha-helical + Ribosomal protein S19 conserved site + S-adenosylmethionine synthetase, N-terminal + Ribosome-binding factor A + Transport-associated OB, type 1 + Sulfotransferase domain + Cell division protein FtsA + Zinc finger, NHR/GATA-type + Lumazine-binding domain + Ribosomal protein L9, bacteria/chloroplast + Glu-tRNAGln amidotransferase C subunit + Glyceraldehyde 3-phosphate dehydrogenase, active site + Ribosomal protein L21 + Peptide methionine sulphoxide reductase MsrA + Valyl-tRNA synthetase, tRNA-binding arm + Ribosomal protein L2, bacterial/organellar-type + Leucine-rich repeat + Alpha/beta hydrolase fold-3 + HpaB/PvcC/4-BUDH N-terminal + Ribosomal protein L14P, conserved site + Glycoside hydrolase family 3 C-terminal domain + NusB antitermination factor + Ribosomal protein L7/L12 + PA14 domain + Pseudouridine synthase, RsuA/RluB/E/F + Ribosomal protein L25 + Glycerol-3-phosphate dehydrogenase, NAD-dependent + Uncharacterised domain YOR215C, mitochondrial + DNA replication/recombination mediator RecO, N-terminal + DNA mismatch repair protein MutS, connector domain + Sodium:dicarboxylate symporter + Peptidase S26A, signal peptidase I, conserved site + DNA mismatch repair protein MutS, N-terminal + CAP domain + Chromosomal replication control, initiator DnaA, conserved site + 3-keto-5-aminohexanoate cleavage enzyme + Glycoside hydrolase family 2, catalytic domain + RecG, wedge domain + S-adenosyl-L-homocysteine hydrolase, conserved site + Ribosomal protein S12, bacterial-type + Maf-like protein + Biotin--acetyl-CoA-carboxylase ligase + Uracil-DNA glycosylase family 4 + ATP synthase, F1 complex, delta/epsilon subunit, N-terminal + Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich + Protein of unknown function DUF3387 + Bifunctional nuclease domain + Ribonucleotide reductase large subunit, N-terminal + DNA polymerase III delta, N-terminal + Beta-L-arabinofuranosidase, GH127 + Chloride channel, core + Protein translocase complex, SecE/Sec61-gamma subunit + R3H domain + Cation-transporting P-type ATPase, C-terminal + Transposase IS605, OrfB, C-terminal + SLC41 divalent cation transporters, integral membrane domain + Uncharacterised protein family UPF0175 + GTP cyclohydrolase I domain + Glutamine synthetase, glycine-rich site + Ribosomal protein L11, bacterial-type + 50S ribosomal protein uL4 + RNA polymerase, beta subunit, conserved site + Thymidylate kinase + Adenylate kinase, active site lid domain + Ribosomal protein L31 + DNA mismatch repair protein MutS-like, N-terminal + Zinc finger, MqsA-type + Recombination protein RecR, C4-type zinc finger + SecE subunit of protein translocation complex + Hydrogenase formation HypD protein + S-adenosylmethionine synthetase, central domain + Phage integrase SAM-like domain + Pyrroline-5-carboxylate reductase, dimerisation domain + Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit + Saccharopine dehydrogenase, C-terminal + Ribosomal protein S19, bacterial-type + Cytochrome b561, bacterial/Ni-hydrogenase + Chorismate synthase, conserved site + Flavodoxin domain + Two component regulator propeller + Mut7-C RNAse domain + Chaperonin Cpn60, conserved site + Ribosomal protein L14P, bacterial-type + Glycine-tRNA ligase, beta subunit + Triosephosphate isomerase, active site + Polysaccharide export protein + Acetyl-CoA hydrolase/transferase C-terminal domain + rRNA small subunit methyltransferase G + Ribosomal protein L18, bacterial-type + Ribonuclease Y, N-terminal + Heat-inducible transcription repressor HrcA, C-terminal + Phosphoribosylglycinamide synthetase, N-terminal + Bordetella uptake gene + Pseudouridine synthase, RluC/RluD + tRNA threonylcarbamoyl adenosine modification protein TsaB + Ribosomal protein S18 + Ribonuclease P + Ribosomal protein L16, conserved site + UDP-N-acetylglucosamine 2-epimerase WecB-like + Double Cache domain 1 + Hydantoinase/oxoprolinase + Molybdopterin cofactor biosynthesis C (MoaC) domain + Ribosomal protein L22, bacterial/chloroplast-type + LemA + ATP synthase, alpha subunit, C-terminal + Ribosomal protein S13, bacterial-type + Shikimate dehydrogenase substrate binding, N-terminal + UvrD-like helicase C-terminal domain + Potassium channel domain + Sulphur relay, DsrE/F-like protein + Periplasmic binding protein/LacI sugar binding domain + Ribosomal protein S9, conserved site + Peptidase S26A, signal peptidase I, lysine active site + TusA-like domain + HNH endonuclease 5 + Regulatory protein RecX + Ribosomal protein L25, beta domain + Uncharacterised protein family UPF0145/C2CD5 + Ribosomal protein S21 + Antibiotic biosynthesis monooxygenase domain + ATP synthase, F0 complex, subunit C + Cation-transporting P-type ATPase, N-terminal + ATPase, OSCP/delta subunit + Peptidyl-tRNA hydrolase, conserved site + Ribosomal protein S13, conserved site + Protein of unknown function DUF169 + Cytidylyltransferase IspD/TarI + 5'-Nucleotidase, C-terminal + Translation elongation factor EFG/EF2 + Phosphoribosylglycinamide synthetase, C-domain + UvrB, YAD/RRR-motif-containing domain + Dihydrodipicolinate reductase, C-terminal + Folylpolyglutamate synthetase + AmmeMemoRadiSam system radical SAM enzyme + Protein of unknown function DUF541 + PRC-barrel domain + DNA glycosylase/AP lyase, H2TH DNA-binding + Transaldolase, active site + Saccharopine dehydrogenase, NADP binding domain + Nitrogen regulatory protein PII + Translation initiation factor aIF-2, bacterial-like + Acetohydroxy acid isomeroreductase C-terminal + GTPase HflX, N-terminal + Cysteinyl-tRNA synthetase, class Ia, DALR + UbiE/COQ5 methyltransferase + Aspartate kinase, conserved site + KaiC-like domain + Pyridoxal phosphate homeostasis protein + Asp/Glu racemase, active site 2 + Ribosomal protein S7, bacterial/organellar-type + Carbamoyl-phosphate synthetase, large subunit oligomerisation domain + UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal + Glycosyl hydrolase, family 4, C-terminal + Alanine racemase, C-terminal + DNA primase, DnaB-helicase binding domain + Ornithine cyclodeaminase, N-terminal + DNA recombination/repair protein RecA, conserved site + DNA mismatch repair protein, C-terminal + MutL, C-terminal, dimerisation + Vitamin B12-dependent methionine synthase, activation domain + DhaL domain + Indole-3-glycerol phosphate synthase + Inositol monophosphatase, metal-binding site + Protein of unknown function DUF167 + Signal recognition particle, SRP54 subunit, M-domain + Glycoside hydrolase, family 42, N-terminal + Spore coat protein CotH + HRDC domain + Ribosomal protein L1, conserved site + CGCAxxGCC motif + Ribosomal protein L3, bacterial/organelle-type + Argininosuccinate synthase, conserved site + Peptidase M42, domain 2 + NADH-quinone reductase NQR2/RnfD + DNA polymerase III, gamma subunit, domain III + Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site + 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain + Aliphatic acid kinase, short-chain, conserved site + Outer membrane protein beta-barrel + Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site + Peptidase S24, LexA-like + Flavodoxin, conserved site + Nuclease associated modular domain 3 + RNA polymerase Rpb1, domain 4 + SecA conserved site + Metal-dependent hydrolase HDOD + Phosphoribulokinase/uridine kinase + Transcription-repair-coupling factor, C-terminal domain + Redoxin + Diaminopimelate decarboxylase, LysA + PhoH-like protein + Protein Iojap/ribosomal silencing factor RsfS + AP endonuclease 1 + Homing endonuclease, LAGLIDADG + Leu/Phe/Val dehydrogenases active site + Membrane transport protein + Tryptophan synthase, alpha chain + DNA recombination RmuC + SbsA, Ig-like domain + Protein of unknown function DUF583 + Nucleoside-triphosphatase, THEP1 type + DNA polymerase III, subunit gamma/ tau + Glutamate-tRNA ligase, bacterial/mitochondrial + Solute carrier family 13 + GH3 family + SAM-dependent methyltransferase RsmB/NOP2-type + Uncharacterised protein family UPF0145 + Ribonuclease III + GTP-binding protein, middle domain + Peptidase M16, zinc-binding site + Ribosomal protein L25, long-form + Zinc finger, DksA/TraR C4-type conserved site + Cell division protein FtsZ, conserved site + N-acetylneuraminic acid synthase, N-terminal + NDUFAF3/Mth938 domain-containing protein + Ribosomal protein L35 + Chloride channel, voltage gated + Sulfur carrier protein FdhD + Sec-independent periplasmic protein translocase TatC + Archease domain + Malate/L-lactate dehydrogenase-like + Ribosomal protein S4, bacterial-type + Aspartate kinase domain + Aspartic peptidase, active site + 5'-Nucleotidase/apyrase + RNA polymerase sigma factor 70, region 1.1 + FMN-binding + Methylene-tetrahydrofolate reductase C-terminal + tRNA pseudouridylate synthase B, C-terminal + Flavodoxin/nitric oxide synthase + Nitrite/sulphite reductase 4Fe-4S domain + GAD domain + Zinc/iron permease + GTPase Der, C-terminal KH-domain-like + Transcription elongation factor, GreA/GreB, conserved site + Xaa-Pro dipeptidyl-peptidase-like domain + NADH-quinone oxidoreductase subunit E-like + Pyruvate kinase + Flavin transferase ApbE + D-alanine--D-alanine ligase/VANA/B/C, conserved site + tRNA(Ile)-lysidine synthase, N-terminal + Ribosomal S11, conserved site + SsrA-binding protein, conserved site + RNA (C5-cytosine) methyltransferase + Schiff base-forming aldolase, conserved site + SAM-dependent chlorinase/fluorinase + AAA C-terminal domain + Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain + Translation elongation factor Ts, conserved site + TadE-like + WD40 repeat, conserved site + 30S ribosomal protein S17 + RTX secretion protein D, Gram-negative bacteria + DNA mismatch repair protein MutS, clamp + Methylated-DNA-[protein]-cysteine S-methyltransferase, active site + Cell division protein FtsZ + Zinc-finger, NAD-dependent DNA ligase C4-type + RNA-binding protein AU-1/Ribonuclease E/G + Periplasmic solute binding protein, ZnuA-like + Fagellar hook-basal body protein, FlgE/F/G + Chromosomal replication control, initiator DnaA + Pyridine nucleotide-disulphide oxidoreductase, class-II, active site + Adenylosuccinate synthase, GTP-binding site + Mandelate racemase/muconate lactonizing enzyme, conserved site + Adenylate kinase subfamily + DNA recombination protein RecR + Putative RNA methylase domain + Tyrosine kinase, G-rich domain + Phage capsid + Cell envelope-related transcriptional attenuator domain + Peptidase C69, dipeptidase A + Phosphohydrolase-associated domain + Exonuclease VII, large subunit, C-terminal + RNA 2',3'-cyclic phosphodiesterase + Acetolactate synthase, small subunit, C-terminal + Ribosomal protein S10, conserved site + Anion-transporting ATPase-like domain + Glycosyltransferase family 28, N-terminal domain + Acetolactate synthase, small subunit + Ribosomal RNA methyltransferase FtsJ domain + Potassium uptake protein TrkA + Amidase, conserved site + Phosphoribosyl-AMP cyclohydrolase domain + Hydantoinaseoxoprolinase, N-terminal + Hypoxanthine phosphoribosyl transferase + Tetracycline resistance protein TetA/multidrug resistance protein MdtG + Peptidase C1A, papain C-terminal + Wzt, C-terminal + EcoEI R protein C-terminal domain + Transcription regulator LexA + Luciferase-like domain + Adenine deaminase C-terminal domain + Domain of unknown function DUF4338 + HPr(Ser) kinase/phosphorylase, N-terminal domain-like + Beta-Casp domain + DEAD/DEAH-box helicase, putative + Proteasome, subunit alpha/beta + UbiB domain + Glucosamine/galactosamine-6-phosphate isomerase + Molybdopterin oxidoreductase, molybdopterin cofactor binding site + Ribosomal protein L15, conserved site + DNA alkylation repair enzyme + Rod shape-determining protein MreC + Ribosome recycling factor + Holliday junction DNA helicase RuvA, C-terminal + tRNA (guanine-N1-)-methyltransferase, bacteria + Rubredoxin domain + Sortase domain + Phosphoglucose isomerase (PGI) + DNA-directed DNA polymerase, family A, conserved site + D-alanine--D-alanine ligase, N-terminal domain + GTP-binding protein LepA, C-terminal + 4-hydroxy-tetrahydrodipicolinate synthase, DapA + Peptidase A24A, N-terminal + Fatty acid desaturase domain + 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase + Serpin domain + Peptidase S16, active site + DNA-directed RNA polymerase, alpha subunit + Dienelactone hydrolase + Imidazoleglycerol-phosphate dehydratase, conserved site + Trigger factor + Diacylglycerol kinase, catalytic domain + Sodium-dependent phosphate transport protein + Serine hydroxymethyltransferase, pyridoxal phosphate binding site + DSBA-like thioredoxin domain + Signal transduction histidine kinase, internal region + DNA polymerase III, delta subunit + Desulfoferrodoxin, ferrous iron-binding domain + N-(5'phosphoribosyl) anthranilate isomerase (PRAI) + Primosomal protein N' + Molybdenum cofactor synthesis C-terminal + Peptidase, FtsH + AmmeMemoRadiSam system protein A + Threonine synthase-like + Translation elongation factor P + Chaperonin GroES, conserved site + Deoxyxylulose-5-phosphate synthase + Bile acid:sodium symporter/arsenical resistance protein Acr3 + RNA polymerase sigma factor 70, ECF, conserved site + HpaB/PvcC/4-BUDH C-terminal + Transcriptional regulator MarR-type, conserved site + Ribosomal protein L35, non-mitochondrial + Ribosomal RNA small subunit methyltransferase E + Pilus retraction protein PilT + Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB + Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site + Protein of unknown function DUF3604 + ATP synthase, F0 complex, subunit A, active site + Peptidase U32 + Large ribosomal RNA subunit accumulation protein YceD + CoA enzyme activase, domain of unknown function DUF2229 + GTPase HflX + Protein-tyrosine phosphatase-like + Translation elongation factor P/YeiP, conserved site + Lysidine-tRNA(Ile) synthetase, C-terminal + MnmE, helical domain + TRAP transporter, 4TM/12TM fusion protein + Sel1-like repeat + Transcription termination factor NusA + Gingipain propeptide + C-terminal-processing peptidase S41A + Glutamate synthase, alpha subunit, C-terminal + Conserved hypothetical protein CHP02688 + Preprotein translocase YajC + N-acetylmuramoyl-L-alanine amidase domain + Translation elongation factor EFTs/EF1B + Domain of unknown function DUF4131 + Rhs repeat-associated core + Tryptophan synthase, beta chain, conserved site + CRISPR-associated protein Cas1 + Protein of unknown function DUF3800 + Ribosomal RNA adenine dimethylase + Dehydroquinase, class II + 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site + DNA translocase FtsK, 4TM region + Mannose-6-phosphate isomerase, type II, C-terminal + Coagulation factor 5/8 C-terminal domain + Ribosomal protein L6, conserved site + Exopolysaccharide synthesis protein + Ankyrin repeat + Pseudouridine synthase I, TruA + Chaperone tailless complex polypeptide 1 (TCP-1) + Glycoside hydrolase family 57, N-terminal domain + Phosphopantetheine-protein transferase domain + Group II intron, maturase-specific + Ribonuclease H domain + DNA mismatch repair, conserved site + Phosphoribosylglycinamide formyltransferase, active site + Hydantoinase B/oxoprolinase + PSP1, C-terminal + Glyceraldehyde-3-phosphate dehydrogenase, type I + Glycoside hydrolase, family 4 + Adenylosuccinate lyase C-terminal + Probable transposase, IS891/IS1136/IS1341 + GidA associated domain 3 + Multiple antibiotic resistance (MarC)-related + Transketolase binding site + Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal + Domain of unknown function DUF1524 + ATP-grasp fold, RimK-type + Alkylhydroperoxidase AhpD core + Acetyl-CoA hydrolase/transferase + Acetyl-CoA carboxylase carboxyl transferase, beta subunit + Protein MM3350-like domain + Ribosomal protein S3, conserved site + MCM domain + Phenol hydroxylase reductase + FemABX peptidyl transferase + Ada-like domain + ThuA-like domain + KDPG/KHG aldolase + MOFRL-associated domain + Ribosomal protein S5, bacterial-type + Phosphoribosylformylglycinamidine synthase subunit PurS + Carbamoyl-phosphate synthase small subunit, N-terminal domain + Magnesium transporter, MgtE intracellular domain + Glycyl-tRNA synthetase + TRAP transporter solute receptor, DctP family + Endoribonuclease YbeY, conserved site + Penicillin/GL-7-ACA/AHL/aculeacin-A acylase + Sortase family + Ribosomal protein S11, bacterial-type + Uncharacterised protein, DhaK domain + Carbohydrate kinase, predicted, conserved site + 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal + CobB/CobQ-like glutamine amidotransferase + Initiation factor 2B alpha/beta/delta + Peptidase M17, leucine aminopeptidase/peptidase B + DXP reductoisomerase C-terminal domain + SAICAR synthetase, conserved site + Uroporphiryn-III C-methyltransferase, conserved site + FeS cluster biogenesis + Leu/Ile/Val-binding protein + Putative phosphate transport regulator + Ribosomal protein L24/L26, conserved site + Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site + Guanylate kinase + Peptidase S9A, N-terminal domain + Co-chaperone DjlA, N-terminal + NAD-dependent DNA ligase, conserved site + Ribosomal protein L27, conserved site + DNA primase, DnaG + Virulence factor BrkB + Chorismate mutase + ABC-type glycine betaine transport system, substrate-binding domain + Lumazine synthase + Ribonuclease toxin, BrnT, of type II toxin-antitoxin system + rRNA small subunit methyltransferase I + Exosortase/Archaeosortase domain + Starch synthase, catalytic domain + Homocysteine biosynthesis enzyme, sulfur-incorporation + Glycosyl transferase, family 35 + Alpha-L-fucosidase, metazoa-type + Hydrogenase expression/formation protein, HupF/HypC + GTP cyclohydrolase I, conserved site + Phenylalanyl-tRNA synthetase, class IIc, alpha subunit + Hydrogenase nickel incorporation protein HypA/HybF + Pyrroline-5-carboxylate reductase + Sodium:neurotransmitter symporter + Ribosomal protein S4, conserved site + Glycine-tRNA ligase, alpha subunit + Bacterial DNA recombination protein RuvA + Exosortase EpsH-related + Inositol monophosphatase, conserved site + Deoxynucleoside kinase domain + Flagellar basal body rod protein, conserved site + MTH1187/YkoF-like + Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase + Carboxylase, conserved domain + DNA polymerase, palm domain + Zinc finger, HypF-type + Endonuclease NucS + DoxX family + Nitrite/Sulfite reductase ferredoxin-like domain + Putative membrane protein insertion efficiency factor + GMP synthase, glutamine amidotransferase + DNA helicase, Holliday junction RuvB type + S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal + tRNA pseudouridine synthase II, TruB + SMP-30/Gluconolactonase/LRE-like region + Histidine-tRNA ligase + Endopeptidase, NLPC/P60 domain + Dihydrodipicolinate reductase + Putative outer membrane lipoprotein-sorting protein + L-fucose isomerase, C-terminal + RagB/SusD domain + SD-repeat containing protein, B domain + Phosphoesterase, HXTX + Riboflavin biosynthesis protein RibD + Methionyl-tRNA formyltransferase + Metallophosphoesterase, YmdB-like + PdxA family + Xanthine/uracil/vitamin C permease + Chromosome segregation/condensation protein ScpB + Glycoside hydrolase, family 65, N-terminal + tRNA-specific 2-thiouridylase + Protein translocase subunit SecD + Domain of unknown function DUF4065 + Plasmid pRiA4b, Orf3 + Peptide methionine sulphoxide reductase MrsB + Dipeptidylpeptidase IV, N-terminal domain + Aromatic amino acid lyase + Ribosomal protein L1, bacterial-type + Ribosomal protein L32p + Peptidase S58, DmpA + AMMECR1 + Ribosomal protein S17, conserved site + Fibronectin type III + Mrp, conserved site + CocE/Serine esterase + Phosphoglycerate/bisphosphoglycerate mutase, active site + DNA ligase, ATP-dependent, central + Rubredoxin, iron-binding site + Glycine cleavage system H-protein, subgroup + NolW-like + Exonuclease VII, small subunit + RNA polymerase sigma factor 54 + Acyltransferase 3 + Phosphoglycerate kinase, conserved site + Ribosomal protein L30, ferredoxin-like fold domain + Protein-export membrane protein SecF, bacterial + Protein of unknown function DUF1468 + Molybdopterin biosynthesis MoaE + P-type ATPase, subfamily IB + Peptidase M15A, C-terminal + Protein-(glutamine-N5) methyltransferase, release factor-specific + Small GTPase superfamily + Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit + Ribosomal protein L5, conserved site + Sec-independent protein translocase protein TatA/E + CobN/magnesium chelatase + Argininosuccinate lyase, C-terminal + Recombination protein RecR, conserved site + Endonuclease V + ATP synthase, F0 complex, subunit C, DCCD-binding site + Uncharacterised protein family UPF0434/Trm112 + BPG-independent PGAM, N-terminal + Holo-[acyl carrier protein] synthase + Phosphodiesterase MJ0936/Vps29 + Domain of unknown function DUF3883 + 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal + Mce/MlaD + Septum formation initiator FtsL/DivIC + Transposase IS30-like HTH domain + DNA polymerase beta, thumb domain + ATP-dependent helicase, C-terminal + FMN-dependent dehydrogenase + Glutathione-dependent formaldehyde-activating enzyme/centromere protein V + Cysteine-tRNA ligase + HAD-superfamily hydrolase,subfamily IIIA + Alpha-L-rhamnosidase RhaM + Ribosome-binding factor A, conserved site + Dihydrodipicolinate reductase, conserved site + Protein of unknown function DUF488 + MOFRL domain + Queuosine biosynthesis protein QueC + Chorismate mutase, type II + Phosphoribosylglycinamide synthetase, conserved site + Histidine triad, conserved site + Nitrogen regulatory protein PII, conserved site + Protein of unknown function DUF2723 + Ribosomal protein S5, N-terminal, conserved site + DNA primase/polymerase, bifunctional, N-terminal + (Uracil-5)-methyltransferase family + Domain of unknown function DUF2007 + Toxin-antitoxin system, antidote protein, HigA + TonB-dependent outer membrane protein SusC/RagA, conserved site + MnmG-related, conserved site + CheC-like domain + RNA 2-O ribose methyltransferase, substrate binding + Transglycosylase SLT domain 2 + Glycoside hydrolase family 38, central domain + DNA helicase, DnaB type + Uncharacterised protein family UPF0251 + Major facilitator, sugar transporter-like + ATPase, V0 complex, c/d subunit + ABC transporter permease MalE + RNA polymerase Rpb2, OB-fold + EVE domain + Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site + Ribonuclease PH, bacterial-type + Aspartate racemase + Sigma 54 modulation/S30EA ribosomal protein, C-terminal + Polyribonucleotide nucleotidyltransferase + Glucose-methanol-choline oxidoreductase, C-terminal + RNA polymerase sigma factor 54, DNA-binding + Homoserine dehydrogenase, conserved site + Transposase, Rhodopirellula-type + Restriction endonuclease, type I, HsdR + Ketopantoate reductase, N-terminal domain + Serine dehydratase-like, alpha subunit + Chaperone protein Skp + Glycosyl transferase, family 20 + Nicotinate/nicotinamide nucleotide adenylyltransferase + Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like + Deoxyribose-phosphate aldolase + OB-fold nucleic acid binding domain + Diaminopimelate epimerase, active site + Argininosuccinate lyase + Terminase, large subunit gp17-like + Ribosomal protein L28/L24 + RDD + ATPase domain + Anthranilate synthase/para-aminobenzoate synthase like domain + Transcription regulator Rrf2-type, conserved site + Ribonucleotide reductase regulator NrdR-like + Ribosomal protein L13, conserved site + DDE domain + Prephenate dehydratase, conserved site + Ribosomal protein L3, conserved site + Cytochrome c oxidase, subunit III, 4-helical bundle + Citrate synthase-like, small alpha subdomain + RidA family + Ribosomal protein S14 + Peptidase S49, serine-peptidase prokaryotes + Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain + S-adenosylmethionine synthetase + Phosphoribosyl pyrophosphate synthetase, conserved site + 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate + UvrABC system, subunit C + Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site + RNA polymerase subunit, RPB6/omega + Homoaconitase/3-isopropylmalate dehydratase, large subunit + Glycosyl transferase WecB/TagA/CpsF + Glycosyl transferase, family 19 + Peptidase M17, leucyl aminopeptidase, N-terminal + Phospholipid biosynthesis protein, PlsX-like + V-type ATPase, V0 complex, 116kDa subunit family + GTP-binding protein TrmE, N-terminal + Aspartate decarboxylase + Cytidylate kinase + RNA methyltransferase, RsmD + Ketol-acid reductoisomerase + Domain of unknown function DUF218 + ATPase, V1 complex, subunit D + MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal + Guanylate kinase, conserved site + Myo-inositol-1-phosphate synthase, GAPDH-like + Dihydropteroate synthase + Radical SAM, C-terminal extension + Riboflavin kinase, bacterial + Putative heavy-metal chelation domain + FG-GAP repeat + N-acetyltransferase RimI/Ard1 + Coenzyme A biosynthesis bifunctional protein CoaBC + VanZ-like + Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 + Aspartate-tRNA ligase, type 1 + Bacteriophage/Gene transfer agent portal protein + Peptidase S9A, prolyl oligopeptidase + Formate-tetrahydrofolate ligase, FTHFS, conserved site + Ribosomal protein S7, conserved site + Domain of unknown function DUF1616 + Phenylalanine-tRNA ligase, class IIc, beta subunit + Formate/nitrite transporter + Domain of unknown function DUF4349 + Methionyl-tRNA synthetase + FecR protein + Sodium:alanine symporter + Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase + Multi-copper polyphenol oxidoreductase + Sulfotransferase + Phosphoribosylglycinamide synthetase + Coenzyme PQQ synthesis D + Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter + Flavoprotein pyridine nucleotide cytochrome reductase + Zinc-finger binding domain of transposase IS66 + BON domain + UvrABC system subunit A + Nicotinate-nucleotide pyrophosphorylase + Lumazine-binding protein + Segregation and condensation protein A + S-adenosylmethionine-dependent methyltransferase + NAD-dependent DNA ligase, active site + tRNA-dihydrouridine synthase, conserved site + Peptidase S8 propeptide/proteinase inhibitor I9 + F1F0 ATP synthase OSCP/delta subunit, N-terminal domain + Pyridoxal phosphate-dependent decarboxylase + Succinylglutamate desuccinylase/aspartoacylase + Ferrous iron transport protein B + Lipid/polyisoprenoid-binding, YceI-like + Ribose 5-phosphate isomerase B + V-type ATPase subunit c domain + Domain of unknown function DUF523 + Intein C-terminal splicing region + NAD-dependent DNA ligase + Biotin protein ligase, C-terminal + tRNA-guanine transglycosylase + Epoxide hydrolase-like + GTP-binding protein EngA + Ribosomal protein L19, conserved site + ATP-citrate lyase/succinyl-CoA ligase, active site + CHAT domain + Aconitase X catalytic domain, putative + Diphthamide synthase domain + Heavy-metal-associated, conserved site + Ribonuclease P, conserved site + EF-hand domain + MgtC/SapB/SrpB/YhiD family + Toxin HigB-like + DNA polymerase III epsilon subunit, exonuclease domain + RNA 3'-terminal phosphate cyclase domain + Protein of unknown function DUF2961 + Leucine rich repeat 4 + Putative Flp pilus-assembly TadG-like, N-terminal + Transposase zinc-binding domain + GTP-binding protein Obg/CgtA + Glucose-methanol-choline oxidoreductase, N-terminal + Organic solvent tolerance-like, N-terminal + S-layer homology domain + Protein of unknown function DUF503 + Protein of unknown function DUF1016 + Anthranilate phosphoribosyl transferase + Phosphocarrier protein HPr-like + Acetylglutamate kinase + Thymidylate kinase, conserved site + Lon protease, bacterial/eukaryotic-type + Glycosyltransferase family 87 + Competence protein ComEA, helix-hairpin-helix domain + THUMP domain + Exonuclease VII, large subunit + Transcriptional regulator MraZ + DNA topoisomerase I, bacterial-type + DNA-binding, RecF, conserved site + Queuosine precursor transporter + Surface presentation of antigen (SpoA) + Endonuclease III, iron-sulphur binding site + Immunoprotective extracellular, immunoglobulin-like domain + D-galactarate/Altronate dehydratase, C-terminal + Peptidase M41, FtsH extracellular + Delta-aminolevulinic acid dehydratase + UDP-3-O-acyl N-acetylglucosamine deacetylase + HAD-superfamily hydrolase, subfamily IIA + MCP methyltransferase, CheR-type + Translation initiation factor 3, conserved site + Phosphotransferase system, enzyme I N-terminal + Xaa-Pro dipeptidyl-peptidase, C-terminal + Gliding motility-associated, C-terminal domain + GTP cyclohydrolase 1 type 2/Nif3 + Orotidine 5'-phosphate decarboxylase, active site + Intein + Protein of unknown function DUF1385 + PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase + Adenosylcobinamide-GDP ribazoletransferase + Chaperone DnaJ + Translation elongation factor EFTu/EF1A, bacterial/organelle + Tetrapyrrole biosynthesis, uroporphyrinogen III synthase + Transposase, zinc-ribbon + CTP synthase + Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site + Lactate/malate dehydrogenase, C-terminal + Hydrogenase accessory protein HypB + DNA polymerase beta-like, N-terminal domain + Domain of unknown function DUF304 + Protein of unknown function DUF2298 + Dehydroquinase, class II, conserved site + Domain of unknown function DUF2341 + Signal-recognition particle receptor FtsY + N-acetyl-gamma-glutamyl-phosphate reductase, type 1 + 16S rRNA processing protein RimM + XdhC Rossmann domain + AP endonuclease 1, binding site + tRNA N6-adenosine threonylcarbamoyltransferase, TsaD + Domain of unknown function DUF1156 + Chaperone DnaK + DNA helicase, ATP-dependent, RecQ type + Cobalamin biosynthesis CobD/CbiB + Domain of unknown function DUF2344 + Adenylosuccinate lyase + Radical-activating enzyme, conserved site + RimM protein + Bacteriophage lambda, GpA + Ppx/GppA phosphatase + DNA methylase, C-5 cytosine-specific, conserved site + dNTP triphosphohydrolase + Ribosomal protein L30, bacterial-type + Tetraacyldisaccharide 4'-kinase + C-type lectin-like/link domain + Desulforodoxin domain + Phospho-N-acetylmuramoyl-pentapeptide transferase + Restriction system protein Mrr-like N-terminal domain + DNA integrity scanning protein, DisA, N-terminal + Peptide chain release factor 1 + RNA polymerase sigma factor 54, core-binding + Asp/Glu racemase, active site 1 + Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ + Protein of unknown function DUF192 + GTP1/OBG, conserved site + Mg chelatase-related protein + Uncharacterised protein family YtxH + TATA-box binding protein + dTDP-4-dehydrorhamnose reductase family + NTP pyrophosphohydrolase MazG + Peptidase M29 + Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like + Glucosamine-fructose-6-phosphate aminotransferase, isomerising + Sugar-binding domain, putative + 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site + Protein of unknown function DUF2206, membrane + Histidinol dehydrogenase, conserved site + Ureohydrolase, manganese-binding site + Uncharacterised protein family UPF0182 + GTP cyclohydrolase I + Electron transfer flavoprotein subunit alpha, conserved site + Ribosome-binding ATPase YchF/Obg-like ATPase 1 + 4-diphosphocytidyl-2C-methyl-D-erythritol kinase + BCCT transporter family + Group II intron reverse transcriptase/maturase + PglZ domain + Nucleoside diphosphate kinase, active site + Ribonuclease PH, conserved site + ClpP, Ser active site + Phosphoribosylformylglycinamidine cyclo-ligase + 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal + 3-oxoacyl-[acyl-carrier-protein] synthase 2 + Bacterial RecJ exonuclease + Phosphofructokinase, conserved site + Glycoside hydrolase family 31 + Molybdenum cofactor biosynthesis C + Glycoside hydrolase family 1 + PIN family, putative toxin-antitoxin system toxin component + Lactate/malate dehydrogenase, N-terminal + Protein of unknown function DUF1573 + Pyridoxamine kinase/Phosphomethylpyrimidine kinase + dTDP-glucose 4,6-dehydratase + UDP-N-acetylenolpyruvoylglucosamine reductase + GTP-binding protein Era + Alpha-glucan phosphorylase + Arsenate reductase-like + Imidazole glycerol phosphate synthase, subunit H + GyrI-like small molecule binding domain + Peptidase S11, D-alanyl-D-alanine carboxypeptidase A + HemN, C-terminal + Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic + Kelch repeat type 1 + tRNA-dihydrouridine synthase, putative, C-terminal + Transcription antitermination protein, NusG, bacteria, conserved site + UDP-N-acetylmuramoylalanine-D-glutamate ligase + Ketopantoate reductase, C-terminal domain + Phosphatidate cytidylyltransferase + Autophagy-related protein 22-like + ATP synthase, F1 complex, delta/epsilon subunit + DNA polymerase type-Y, HhH motif + Uncharacterised protein family YfhO + Transcription elongation factor GreA + Ribonucleotide reductase, adenosylcobalamin-dependent + Sulphate adenylyltransferase catalytic domain + Peptidase S49, SppA + CCB3/YggT + GHMP kinase, ATP-binding, conserved site + Dna2/Cas4, domain of unknown function DUF83 + Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain + Cobinamide kinase/cobinamide phosphate guanyltransferase + Herpesvirus/Caudovirus protease domain + Transcription termination factor Rho + Fructose-1,6-bisphosphatase, class V + Selenophosphate synthetase + Na+/H+ antiporter, NhaC-like, C-terminal + L-seryl-tRNA selenium transferase-like + ATP-dependent DNA helicase RecQ, zinc-binding domain + GtrA-like protein + Prolyl-tRNA synthetase, class IIa, bacterial-type + Transposase, putative, helix-turn-helix domain + Aerotolerance regulator, N-terminal + Type IX secretion system membrane protein, PorP/SprF family + Histidinol-phosphate aminotransferase family + PdxS/SNZ N-terminal domain + Archaeal PaREP1 + Organic radical enzyme activase + Uridylate kinase, bacteria + YerB-like + Uncharacterised protein GYD + Zinc finger C2H2-type + DRTGG + YD repeat + Succinate dehydogenase/fumarate reductase N-terminal + Peptidase M6-like, domain + 3-oxoacyl-(acyl-carrier-protein) reductase + YVTN beta-propeller repeat + ATP synthase, F0 complex, subunit C, bacterial/chloroplast + Peptide chain release factor 2 + Glutamine synthetase, N-terminal conserved site + DNA repair protein RadA + Histidine kinase, N-terminal 7TM region + Riboflavin-specific deaminase, C-terminal + Hydroxymethylglutaryl-CoA reductase, class I/II + Phosphoribosyl-ATP pyrophosphohydrolase-like + Cytochrome P450 + Tryptophan synthase, alpha chain, active site + Alpha-L-rhamnosidase, six-hairpin glycosidase domain + Adenosine/AMP deaminase domain + Putative small multi-drug export + Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG + Protein of unknown function DUF4870 + RNA polymerase, subunit omega/K/RPB6 + LexA-binding, inner membrane-associated putative hydrolase + Alanine racemase, pyridoxal-phosphate attachment site + Ribosomal protein L11, conserved site + Fatty acid hydroxylase + Membrane insertase YidC, N-terminal + ATP synthase, F1 complex, beta subunit + Prokaryotic transglycosylase, active site + Glutamate 5-kinase, conserved site + PBS lyase HEAT-like repeat + Virulence protein RhuM-like + Cell cycle, FtsW / RodA / SpoVE, conserved site + LarC/UPF0272 + Glycoside hydrolase, family 13, N-terminal + SagB-type dehydrogenase domain + C4-type zinc ribbon domain + 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site + Ribosomal protein S14, conserved site + ATPase, V1 complex, subunit F + Indole-3-glycerol phosphate synthase, conserved site + Dodecin-like + DAGK family + BlaI transcriptional regulatory family + UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region + Alkaline shock protein Asp23 + Phage shock protein, PspC, N-terminal + Lysine-tRNA ligase, class II + Glycosyl hydrolase family 92 + Methylthioribose-1-phosphate isomerase + Yip1 domain + UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase + ATPsynthase alpha/beta subunit, N-terminal extension + UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal + 3-hydroxyacyl-CoA dehydrogenase, conserved site + Na+/H+ antiporter subunit E + Domain of unknown function DUF448 + Dihydrolipoamide dehydrogenase + Zinc finger, ClpX C4-type + Ribosomal protein L28 + Purple acid phosphatase, N-terminal + Uncharacterised protein family HicB + IPT domain + PASTA domain + CDP-glycerol glycerophosphotransferase + SusD-like, N-terminal + Carbonic anhydrase + Phosphatidylethanolamine-binding protein + Winged helix-turn helix domain + Pilus assembly protein, PilO + Thiamine-monophosphate kinase + Transcription regulator, HTH DeoR-type, conserved site + Histidine biosynthesis, HisF + Virulence-associated protein D / CRISPR associated protein Cas2 + Adenylosuccinate synthase, active site + Acetyl xylan esterase + Type II secretion system protein G + Hydrogenase expression/formation protein HypE + Mitochondrial biogenesis protein AIM24 + Type II secretion system conserved site + Outer membrane protein transport protein (OMPP1/FadL/TodX) + Dodecin + Na(+)/H(+) antiporter subunit F-like + Thioredoxin reductase + Galactokinase galactose-binding domain + Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site + Transposase IS66, Orf2 + Phage tail tape measure protein + Galactokinase/homoserine kinase + Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal + Pyridoxal 5'-phosphate synthase subunit PdxT/SNO + RelA/SpoT family + Proteinase inhibitor I42, chagasin + L-asparaginase, N-terminal + Uncharacterised hydrolase TatD-type + Thiamine-binding protein + Branched-chain amino acid aminotransferase I + Glutamate-ammonia ligase adenylyltransferase, repeated domain + Cyclodeaminase/cyclohydrolase + 3D domain + Ccc1 family + ATP-grasp fold, DUF201-type + Gamma-glutamyl phosphate reductase GPR, conserved site + Phenazine biosynthesis PhzF protein + Protein of unknown function DUF499 + Helix-turn-helix, HxlR type + Tex-like domain + Porphobilinogen deaminase, N-terminal + DNA mismatch repair protein family + CRISPR-associated endonuclease Cas2 + Peptidase C45 + NADH-ubiquinone oxidoreductase, 20 Kd subunit + CRISPR type III-associated RAMP protein + ATP synthase, F1 complex, gamma subunit conserved site + Glycosyl hydrolase family 32, N-terminal + Protein of unknown function DUF721/UPF0232 + Transmembrane secretion effector + Heparin-sulfate lyase, N-terminal + Thiamine phosphate synthase + Succinyl-CoA synthetase, beta subunit, conserved site + Methyladenine glycosylase + Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal + DNA polymerase 1 + Geranylgeranyl reductase family + Formamidopyrimidine-DNA glycosylase + NADH:ubiquinone oxidoreductase, subunit 1, conserved site + DNA-binding transcriptional activator AlpA + FAS1 domain + DinB-like domain + UvrABC system, subunit B + Sortilin, N-terminal + Fimbrial assembly PilN + Na+/H+ antiporter subunit G + POTRA domain, FtsQ-type + Protein of unknown function DUF2851 + Ammonium transporter, conserved site + Phosphate transport system protein PhoU + Sialate O-acetylesterase domain + Transcriptional regulator, AbiEi antitoxin + Type III secretion system FHIPEP + Alpha-2-macroglobulin + Phosphatidylserine decarboxylase-related + Malonyl CoA-acyl carrier protein transacylase, FabD-type + DEAD box helicase DbpA/CsdA, RNA-binding domain + Ribonuclease Y + 3-hydroxyisobutyrate dehydrogenase-related, conserved site + ATP synthase, F1 complex, alpha subunit + YicC-like, N-terminal + AMP-binding + Peptidase M50, putative membrane-associated zinc metallopeptidase + Chemotaxis receptor methyltransferase CheR, N-terminal + Conserved hypothetical protein CHP00275, flavoprotein HI0933-like + Collagen triple helix repeat + Cytochrome c oxidase, subunit I, copper-binding site + SIMIBI class G3E GTPase, ArgK/MeaB + 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase + Di-haem cytochrome c peroxidase + ATP-sulfurylase PUA-like domain + UbiE/COQ5 methyltransferase, conserved site + Probable zinc-binding domain + Alpha-2-macroglobulin, N-terminal + Sirohaem synthase, N-terminal + Domain of unknown function DUF5060 + Daunorubicin resistance ABC transporter ATP-binding subunit DrrA + LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 + Endonuclease III-like, conserved site-2 + Formate dehydrogenase, alpha subunit + Thil, AANH domain + D-alanine--D-alanine ligase + ABC transporter, substrate-binding protein + CCA-adding enzyme, C-terminal + N-acetyl-gamma-glutamyl-phosphate reductase, active site + Haemerythrin-like + Domain of unknown function DUF302 + Acetyl-CoA biotin carboxyl carrier + Cytochrome c oxidase-like subunit III + GTP cyclohydrolase II, RibA + DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site + Protein of unknown function DUF1232 + Domain of unknown function DUF4040 + Protein of unknown function DUF1566 + PPC domain + Fic/DOC N-terminal + Acetyl-CoA carboxylase, alpha subunit + Type III secretion system substrate exporter + UDP-N-acetylglucosamine 1-carboxyvinyltransferase + XdhC- CoxI + Uncharacterised protein family UPF0261 + Opine dehydrogenase + Protein of unknown function DUF885 + SAP domain + Polyketide cyclase/dehydrase + IMP dehydrogenase / GMP reductase, conserved site + Shikimate dehydrogenase + Acetolactate synthase, large subunit, biosynthetic + Galactose-1-phosphate uridyl transferase, N-terminal + Nitrogen regulatory protein P-II, urydylation site + AsmA-like, C-terminal + Na+/H+ antiporter MnhB subunit-related protein + CYTH domain + Beta-galactosidase trimerisation + ClpP, histidine active site + L-lactate/malate dehydrogenase + Trehalose-phosphatase + Thymidine kinase + Dihydroorotase + Octanoyltransferase + Methylmalonyl-CoA epimerase + tRNA-specific adenosine deaminase + Urocanase, Rossmann-like domain + 5-formyltetrahydrofolate cyclo-ligase + Fibronectin type III-like domain + ATP-citrate lyase/succinyl-CoA ligase, conserved site + UDP-N-acetylmuramate--L-alanine ligase + Peptidase M29, N-terminal + Regulator of chromosome condensation, RCC1 + Protein-tyrosine phosphatase, low molecular weight + Octanoyltransferase, conserved site + tRNA (guanine-N-7) methyltransferase, Trmb type + Bacteriophage/plasmid primase, P4, C-terminal + Toxin HigB-1 + Protein of unknown function DUF1501 + Udp N-acetylglucosamine O-acyltransferase, C-terminal + Lipopolysaccharide kinase + AMIN domain + RNA-directed DNA polymerase (reverse transcriptase), msDNA + ABC transporter Uup, C-terminal + Uncharacterised protein family UPF0236 + Curli production assembly/transport component CsgG + Type IV secretion system coupling protein TraD, DNA-binding domain + Aldose 1-/Glucose-6-phosphate 1-epimerase + RNA methyltransferase TrmA, active site + Roadblock/LAMTOR2 domain + Tryptophan synthase, beta chain + Large-conductance mechanosensitive channel + Pyrimidine nucleoside phosphorylase, C-terminal + Shikimate kinase, conserved site + Protein of unknown function DUF763 + RsgA GTPase domain + 3-oxoacyl-[acyl-carrier-protein] synthase 3 + Zincin-like metallopeptidase + Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase + G-protein beta WD-40 repeat + NrfD family + AF2212-like domain + CO dehydrogenase/acetyl-CoA synthase complex beta subunit + Membrane bound O-acyl transferase, MBOAT + Urocanase, C-terminal domain + Domain of unknown function DUF1732 + Conserved hypothetical protein CHP04076 + NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 + Cyclic nucleotide-binding, conserved site + Transposase IS204/IS1001/IS1096/IS1165, zinc-finger + dCTP deaminase + Domain of unknown function DUF4382 + RQC domain + Bacterial transcriptional activator domain + RNA polymerase sigma factor RpoD, C-terminal + UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal + Jag, N-terminal + 6-phosphogluconate dehydrogenase, C-terminal + DNA mismatch endonuclease vsr + ATPase, V1/A1 complex, subunit E + Ribosomal protein L2, conserved site + Twin-arginine translocation protein TatB-like + Glucose/Sorbosone dehydrogenase + HipA-like, C-terminal + DNA-directed RNA polymerase, subunit beta-prime + Outer membrane protein beta-barrel domain + Thiol:disulfide interchange protein DsbD, N-terminal domain + DNA-binding, RecF + Protein of unknown function DUF123 + Transcription regulator TrmB, N-terminal + Cysteine peptidase, cysteine active site + Orotidine 5'-phosphate decarboxylase, type 2 + Domain of unknown function DUF128 + Ethanolamine utilization protein EutN/carboxysome structural protein Ccml + Ferrochelatase + Domain of unknown function DUF4213 + Endonuclease III-like, iron-sulphur cluster loop motif + Heat-inducible transcription repressor HrcA + Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit + Domain of unknown function DUF2520 + NIL domain + RHS repeat + Glycine cleavage system T protein + Adenylyl-sulfate kinase + 3-dehydroquinate synthase AroB + Ribosomal protein L33 + Flavodoxin-like fold + Putative auto-transporter adhesin, head GIN domain + Uncharacterised protein family CoxE-like + 6-phosphogluconate dehydrogenase + 1-deoxy-D-xylulose 5-phosphate reductoisomerase + KAP family P-loop domain + Protein of unknown function DUF1127 + Nuclease-related domain, NERD + S-adenosylmethionine decarboxylase, core + Serpin, conserved site + Urocanase, N-terminal domain + Lipoyl synthase + UDP-glucose 4-epimerase + Phosphate ABC transporter, permease protein PstC + Glutamyl-tRNA(Gln) amidotransferase A subunit + Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA + Protein of unknown function DUF4838 + Uroporphyrin-III C-methyltransferase + Integral membrane protein 1906 + Conserved TM helix + FeS cluster insertion protein + YutG/PgpA domain + Dual-specificity RNA methyltransferase RlmN + NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 + Methane oxygenase PmoA + DNA primase, phage/plasmid + Glycoside hydrolase family 20, catalytic domain + Phosphotransferase system, HPr histidine phosphorylation site + Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B + Formylmethanofuran dehydrogenase, subunit E domain + Aspartate-semialdehyde dehydrogenase, conserved site + Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain + Outer membrane lipoprotein carrier protein LolA-like + Aspartate-semialdehyde dehydrogenase, beta-type + DNA-directed DNA polymerase, family B, multifunctional domain + Protein of unknown function DUF2892 + Copper chaperone SCO1/SenC + Carbamoyl-phosphate synthase, small subunit + DnaD-like domain + Galactokinase + Capsule polysaccharide biosynthesis + Porphobilinogen deaminase + Sulfolobus virus STSV1, Orf64 + Protein MutL + RNA-binding protein, predicted + Proline-tRNA ligase, class II, C-terminal + UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase + Protein of unknown function DUF465 + 7Fe ferredoxin + Beta-hexosaminidase, bacteial type, N-terminal + Amidophosphoribosyltransferase + Cysteine synthase + Putative LytR/CpsA/Psr regulator, C-terminal domain + Phosphoribosylformylglycinamidine synthase subunit PurQ + Polyphosphate kinase C-terminal domain + Elongation factor 4 + Helix-turn-helix protein RpiR + Nitrogenase/oxidoreductase, component 1 + TonB-dependent outer membrane protein, SusC/RagA + Crossover junction endodeoxyribonuclease, RusA-like + Domain of unknown function DUF1638 + Ion transport domain + ATP:cob(I)alamin adenosyltransferase, PduO-type + Carbamoyltransferase + AP endonuclease, family 2, C-terminal + Cardiolipin synthase N-terminal + Coproporphyrinogen III oxidase, oxygen-independent related + Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain + Hydrogenase assembly chaperone, conserved site + GPR domain + Two component regulator three Y + 5'-Nucleotidase, conserved site + Protein of unknown function DUF917 + Magnesium transporter MgtE + Aerotolerance-related protein BatD + N-formylglutamate amidohydrolase + LPS export ABC transporter, ATP-binding protein LptB + Domain of unknown function DUF1214 + Methylthioadenosine phosphorylase (MTAP) + Protein of unknown function DUF502 + Peptidase M56 + Dihydroneopterin aldolase/epimerase domain + Tubulin, conserved site + Anhydro-N-acetylmuramic acid kinase + Sporulation stage II protein D, amidase enhancer LytB N-terminal + Protein of unknown function DUF1670 + MutY, C-terminal + 3-phosphoshikimate 1-carboxyvinyltransferase + ADP-glucose pyrophosphorylase, conserved site + Cytochrome b/b6-like domain + Metal-dependent phosphohydrolase, 7TM extracellular domain + Monomethylamine methyltransferase MtmB + Orotate phosphoribosyl transferase domain + Intron endonuclease, group I + Glucose-6-phosphate dehydrogenase, C-terminal + Citrate synthase active site + Methionyl-tRNA synthetase, beta subunit, C-terminal + Succinyl-CoA ligase, alpha subunit + DNA mismatch repair protein MutS + Ribosomal protein L10, eubacterial, conserved site + Metal-dependent phosphohydrolase, 7TM intracellular domain + Domain of unknown function DUF4145 + Intramolecular chaperone auto-processing domain + AP endonuclease 2, zinc binding site + Type III secretion system substrate exporter, C-terminal + Peptidase S13, D-Ala-D-Ala carboxypeptidase C + Signal recognition particle protein Ffh + Carbohydrate-binding, CenC-like + Penicillin-binding protein 2 + S-adenosylmethionine decarboxylase family, prokaryotic + Protein of unknown function DUF3048, C-terminal domain + CAAX prenyl protease 1, N-terminal + Ribosomal protein L23/L25, conserved site + Protease PrsW + Glucose-6-phosphate dehydrogenase, NAD-binding + DNA gyrase, subunit B + Helicase HerA-like C-terminal + Molybdenum cofactor biosynthesis protein A + CstA, N-terminal domain + Ribonucleotide reductase small subunit family + Listeria/Bacterioides repeat + Domain of unknown function DUF1730 + Aldo/keto reductase, conserved site + Deoxyuridine triphosphate nucleotidohydrolase + Protein of unknown function DUF2207, membrane + Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ + Domain of unknown function DUF255 + Mycobacterial 4 TMS phage holin, superfamily IV + Purine phosphorylase, family 2, conserved site + Ribosomal protein L35, conserved site + Domain of unknown function DUF4070 + N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase + NADH-quinone oxidoreductase, chain M/4 + GLUG + Domain of unknown function DUF4268 + RNA methyltransferase RlmH + Glycoside hydrolase, family 43 + CxxC-x17-CxxC domain + Intein N-terminal splicing region + Na-Ca exchanger/integrin-beta4 + Pectate lyase superfamily protein + Phosphate transport system permease protein PstA + Cell shape-determining protein MreD + Cyclin-like + Ribulose bisphosphate carboxylase, large subunit, C-terminal + Bacterial antitoxin of type II TA system, VapB + Asparagine synthase, glutamine-hydrolyzing + Phosphoribosylaminoimidazole-succinocarboxamide synthase + ASPIC/UnbV + Translocation and assembly module TamB + Cell division protein ZapA-like + Phosphoglucose isomerase, conserved site + Heat shock protein Hsp90 family + DNA polymerase family X, beta-like + Clp protease, ATP-binding subunit ClpX + Phosphoribosylglycinamide formyltransferase + Domain of unknown function DUF820 + HTH-type transcriptional regulator AraC-type, N-terminal + FAD-dependent glycerol-3-phosphate dehydrogenase + Ribosome biogenesis GTPase RsgA + Histidinol-phosphate phosphatase + Transcription-repair coupling factor + Ribose 5-phosphate isomerase, type A + Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent + Solute-binding protein family 3, conserved site + Ribosome maturation factor RimP, N-terminal + Protein of unknown function DUF3048, N-terminal + Formiminotransferase, N-terminal subdomain + Probable epoxyqueuosine reductase QueH + Glycoside hydrolase, family 77 + Phosphate-selective porin O/P + Zinc finger, SWIM-type + Reductive dehalogenase domain + ATP-dependent DNA helicase RecG + Outer membrane protein assembly factor BamD + Translin, N-terminal + Lipopolysaccharide assembly, LptC-related + Putative glycohydrolase domain DUF4038 + SOS response associated peptidase (SRAP) + RNA methyltransferase TrmH family + Domain of unknown function DUF4405 + Protein of unknown function DUF401 + Glutamate racemase + GDP-mannose 4,6-dehydratase + Flagellar P-ring protein + Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 + Protein of unknown function DUF3467 + ResB-like domain + Isocitrate dehydrogenase NADP-dependent, monomeric + Motility protein B, N-terminal domain + Pheromone shutdown, TraB + tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG + Glutamate synthase, central-N + Domain of unknown function DUF4159 + Flavin prenyltransferase UbiX/Pad1 + SAM-dependent methyltransferase RsmI, conserved site + Thiosulphate sulfurtransferase, conserved site + Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 + Domain of unknown function DUF4091 + ATP synthase, F0 complex, subunit b, bacterial + Protein of unknown function DUF2924 + PA domain + WbqC-like protein family + Ribosomal protein L34 + Thiazole synthase ThiG + Phospholipase/carboxylesterase/thioesterase + Ribonuclease E/G + ABC-type uncharacterised transport system + Intradiol ring-cleavage dioxygenase, core + Glycoside hydrolase, family 2 + DnaD domain + Peroxide stress protein YaaA + Na/H antiporter domain + Protein of unknown function DUF3108 + YbhB/YbcL + Alpha-2-macroglobulin, N-terminal 2 + Phage terminase large subunit, N-terminal + KilA-N, DNA-binding domain + Transposase TnpC, homeodomain + RapZ-like family + Tex-like protein, N-terminal + NurA domain + Peptidase C26 + RnfC Barrel sandwich hybrid domain + Copper amine oxidase-like, N-terminal + Phosphoribosyl-ATP pyrophosphohydrolase + Neurolysin/Thimet oligopeptidase, N-terminal + Epoxyqueuosine reductase QueG + Peptidase, C-terminal, archaeal/bacterial + Protein of unknown function DUF3368 + Anaerobic ribonucleoside-triphosphate reductase activating protein + Peptidase S9, serine active site + MTH538 TIR-like domain + Protein of unknown function DUF2791 + Glycosyltransferase WbsX + Essential recombination function protein + Domain of unknown function DUF4342 + TonB-dependent receptor, conserved site + Putative transposase IS4/IS5 family + Na+/H+ antiporter NhaA + Lactonase, 7-bladed beta propeller + NAD-glutamate dehydrogenase + Prohead protease + Cytochrome c-type biogenesis protein CcmF, C-terminal + Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain + Organic solvent tolerance protein, C-terminal + Glycoside hydrolase, family 3, active site + Apolipoprotein N-acyltransferase + Pyridoxamine 5'-phosphate oxidase-related + Transcription regulator MerR, DNA binding + Inorganic pyrophosphatase + Putative neutral zinc metallopeptidase + Aconitase X swivel domain, putative + Protein of unknown function DUF917, N-terminal + Three-Cys-motif partner protein + MT-A70-like + BioY protein + Tex protein, YqgF-like domain + Thymidylate synthase + Sodium/solute symporter, conserved site + L-fucose isomerase, N-terminal-1 + Double Cache domain 2 + Orn/DAP/Arg decarboxylase 2, conserved site + ATP synthase delta/epsilon subunit, C-terminal domain + Domain of unknown function DUF814 + Ribosome maturation factor RimP, C-terminal + Protein CR006, P-loop domain + SPFH domain, YdjI-like + Bacterial periplasmic spermidine/putrescine-binding protein + Protein of unknown function DUF4012 + Phosphotransferase system, mannose-type IIA component + ECF transporter, substrate-specific component + RidA, conserved site + Porphobilinogen deaminase, C-terminal + Adaptor protein ClpS, core + NRAMP family + CopG antitoxin + Cytochrome c, class IA/ IB + Cobalamin (vitamin B12) biosynthesis CbiM family + Domain of unknown function DUF2062 + NADH:cytochrome b5 reductase (CBR) + Oligopeptidase F, N-terminal domain + Isoprenylcysteine carboxyl methyltransferase + Alpha-galactosidase, NEW3 domain + Voltage-gated potassium channel + Conserved hypothetical protein CHP00725 + Agmatinase-related + Asparaginase/glutaminase-like + Acyl-CoA thioester hydrolase YbgC/YbaW family + Restriction endonuclease, type II, TdeIII + DsrE2-like family + Arsenical pump ATPase, ArsA/GET3 + Formate/nitrite transporter, conserved site + DNA-directed RNA polymerase, omega subunit + Abortive bacteriophage infection, resistance + Mannonate dehydratase + CRISPR-associated Cas3-HD domain + Metal-sensitive transcriptional repressor + Fumarase C, C-terminal + Dihydroxy-acid dehydratase + Flagellar motor switch protein FliG + Anti-sigma factor antagonist + MiaB-like tRNA modifying enzyme + Penicillin amidase type, domain1 + Domain of unknown function DUF3786 + Protein of unknown function DUF917, C-terminal + Peptidase M32, carboxypeptidase Taq + Histidine kinase CheA-like, homodimeric domain + NADPH-dependent 7-cyano-7-deazaguanine reductase QueF + Glucose-1-phosphate thymidylyltransferase, short form + Protein of unknown function DUF5131 + Glutaredoxin active site + Doubled CXXCH motif + Formiminotransferase, C-terminal subdomain + Protein of unknown function DUF2085, transmembrane + Putative peptidoglycan binding domain + Uncharacterised protein family UPF0066, conserved site + AbiEi antitoxin C-terminal domain + Orotidine 5'-phosphate decarboxylase + Uncharacterised conserved protein UCP016719 + Domain of unknown function DUF1254 + Leucyl/phenylalanyl-tRNA-protein transferase + Cytochrome ubiquinol oxidase subunit 1 + Type IV secretion system protein TraG/VirD4 + Portal protein + GTP cyclohydrolase FolE2/MptA + Pirin, N-terminal domain + Phosphate transport system permease protein 1 + Tex-like protein, HTH domain + Cell division protein FtsQ/DivIB + Glycosyl hydrolase 36, catalytic domain + Next to BRCA1, central domain + Succinate--CoA synthetase, beta subunit + RNA methyltransferase TrmA, conserved site + AP endonuclease 2 + Carbamoyltransferase, HypF-type + DNA sulphur modification protein DndB + AsmA + Protein of unknown function DUF3489 + Electron transfer flavoprotein, beta-subunit, conserved site + LUD domain + Sodium ion-translocating decarboxylase + Ribonuclease R winged-helix domain + DGQHR-containing domain + Uncharacterised protein family UPF0165 + PdxT/SNO family, conserved site + Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site + Putative Ig + Haem-degrading + Glycosyl hydrolase 94 + Cyclic nucleotide-regulated ion channel, N-terminal domain + Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain + DNA ligase, ATP-dependent, C-terminal + Manganese/iron superoxide dismutase, C-terminal + Domain of unknown function DUF1801 + Glycoside hydrolase, family 25 + Thiazole biosynthetic enzyme Thi4 family + 2TM domain + CHASE2 + Domain of unknown function DUF1330 + Domain of unknown function DUF4129 + UbiA prenyltransferase conserved site + SMCs flexible hinge + Peptidase A24A, prepilin type IV, bacterial + Vancomycin resistance VanW + Tricorn protease C1 domain + 5-methylcytosine restriction system component + Phosphotransferase system, enzyme I-like + Peptidase M22, conserved site + Delta-aminolevulinic acid dehydratase, active site + Sulphur transfer protein DsrC/TusE + Adenosine specific kinase + DNA mismatch repair MutH/Restriction endonuclease, type II + Heat shock protein Hsp90, N-terminal + Arm, DNA-binding domain + Sodium/potassium/calcium exchanger + Pseudouridine synthase, TruD + Prokaryotic glutathione synthetase, ATP-binding + Peptidase S26 + Haem oxygenase-like, multi-helical + AdipoR/Haemolysin-III-related + Ribosomal protein L29, conserved site + Fructose-1-6-bisphosphatase class I, N-terminal + Lipopolysaccharide assembly protein A domain + Glutaredoxin subgroup + Malic enzyme, conserved site + Serine proteases, trypsin domain + Transaldolase type 3B/Fructose-6-phosphate aldolase + Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type + Membrane associated eicosanoid/glutathione metabolism-like domain + MvaI/BcnI restriction endonuclease + Peptidase T2, asparaginase 2 + Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain + Domain of unknown function DUF4332 + Glycosyl hydrolase-like 10 + Succinate dehydrogenase/fumarate reductase iron-sulphur protein + Ribonuclease J + Translation elongation factor SelB, winged helix, type 3 + Chromate transporter + Deoxyguanosinetriphosphate triphosphohydrolase, C-terminal domain + Electron transport complex, subunit RnfC/RsxC + Ribosomal protein L34, conserved site + Glyoxalase I, conserved site + Cytidine deaminase, homotetrameric + Flagellin + Protein of unknown function DUF2442 + Protein of unknown function DUF354 + Glycogen phosphorylase, domain of unknown function DUF3417 + LPS-assembly lipoprotein LptE + ATP-dependent protease, HslV subunit + Tagaturonate epimerase + Flp pilus assembly protein RcpC/CpaB domain + Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal + Peptidase S26B + NADP transhydrogenase beta-like domain + TraD/TraG, TraM recognition site + Acetyl-CoA dehydrogenase-like C-terminal domain + L-asparaginase, C-terminal domain + Phosphotransferase system, EIIB component, type 2/3 + Polyphosphate kinase middle domain + Impact, N-terminal + Protein of unknown function DUF3987) + Proline racemase family + CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase + Glycoside hydrolase family 36 + YHS domain + 3Fe-4S ferredoxin + Pilus assembly, Flp-type CpaB + NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site + Glutamine synthetase type I + BolA protein + SAM-dependent methyltransferase TRM5/TYW2-type + Peptidase M54, archaemetzincin + Double transmembrane domain + Peptidase C11, clostripain + TPM domain + Threonine synthase, N-terminal + Carbamoyl-phosphate synthase, large subunit + GTP-binding protein, ribosome biogenesis, YsxC + Glycosyl-hydrolase family 116, N-terminal + Protein of unknown function DUF1006 + Isopropylmalate dehydrogenase + Divergent polysaccharide deacetylase + Domain of unknown function DUF4388 + Manganese/iron superoxide dismutase + DNA-directed RNA polymerase beta subunit, bacterial-type + Glycosyl hydrolase family 95, N-terminal domain + Diacylglycerol/lipid kinase + HflK + Haem peroxidase, plant/fungal/bacterial + DNA recombination and repair protein Rad51-like, C-terminal + L-arabinose isomerase + Serine dehydratase beta chain + Cytochrome c-552/4 + FAD dependent oxidoreductase, central domain + Acetamidase/Formamidase + Dihydrofolate reductase domain + Domain of unknown function DUF306, Meta/HslJ + Cytochrome P450, conserved site + Lysine-2,3-aminomutase/glutamate 2,3-aminomutase + Ribosomal protein S12 methylthiotransferase RimO + Cytidylate kinase-like family + AraC-type arabinose-binding/dimerisation domain + Urocanase conserved site + Glutamate synthase (NADPH), homotetrameric + COX15/CtaA family + Manganese/iron superoxide dismutase, N-terminal + Uncharacterised domain CGGC-dom + Flp/Fap pilin component + Bacterial protein export chaperone SecB + Ribosomal protein S18, conserved site + Alkaline phosphatase D-related + Uncharacterised protein family UPF0012, conserved site + Stage II sporulation protein M-like + Sugar fermentation stimulation protein + Bax inhibitor 1-related + Domain of unknown function DUF4115 + Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain + Oxoglutarate/iron-dependent dioxygenase + Oligosaccharyl transferase, STT3 subunit + Outer membrane protein, OmpA-like, conserved site + Domain of unknown function DUF1624 + 3-oxoacid CoA-transferase, subunit A + Flagellar basal body-associated protein FliL + CRISPR-associated protein, Cas5 + Glycosyl-hydrolase family 116, catalytic region + Glycerate kinase + Biotin and thiamin synthesis-associated domain + HipA, N-terminal subdomain 1 + Formate C-acetyltransferase glycine radical, conserved site + Glucose-6-phosphate dehydrogenase + Ribosomal protein L22/L17, conserved site + Transcription factor zinc-finger + DhaK domain + YhhN-like + Phage portal protein, lambda family + Transcription factor TFIIB + Uncharacterised protein family UPF0061 + SHOCT domain + Competence-induced protein CinA + Carbamoyltransferase, C-terminal + Phosphosugar isomerase, KdsD/KpsF-type + Proline dehydrogenase domain + Thrombospondin, type 3-like repeat + Domain of unknown function DUF2179 + Glycoside hydrolase family 16 + Cytochrome c-type biogenesis protein + Ketopantoate reductase ApbA/PanE + Peptidase family S66 + Phosphoenolpyruvate synthase + Condensation domain + Aminopeptidase P, N-terminal + PepSY-associated TM protein + ATPase, OSCP/delta subunit, conserved site + GWxTD domain + Type III secretion system inner membrane R protein + Beta-hexosaminidase + Uronate isomerase + Phosphoribosylformylglycinamidine subunit PurL + Conserved hypothetical protein CHP04255 + Cysteine synthase CysK + Acetylornithine/Succinylornithine transaminase family + Protein of unknown function DUF429 + Protein of unknown function DUF4198 + Molybdenum cofactor sulfurase, C-terminal + Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ + Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase + G5 domain + Purine nucleoside phosphorylase + Glucokinase + Protein of unknown function DUF3096 + Domain of unknown function DUF234, DEXX-box ATPase C-terminal + CRISPR-associated protein Cas5, N-terminal + SprB repeat + Type III secretion system inner membrane P protein + Sialic acid O-acyltransferase NeuD-like + Conserved hypothetical protein CHP02391 + Methylpurine-DNA glycosylase (MPG) + Cyclic-di-AMP receptor + Transcription factor TFIIB, cyclin-like domain + Mannitol dehydrogenase, C-terminal + NADH-plastoquinone oxidoreductase, chain 5 subgroup + Aromatic-ring-hydroxylating dioxygenase, alpha subunit + Peptidase M55, D-aminopeptidase + VIT domain + Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic + Putative nitroreductase TM1586 + Acetate-CoA ligase + Lipopolysaccharide export system protein LptC + RNA 3'-terminal phosphate cyclase, insert domain + DNA ligase, ATP-dependent, N-terminal + Iron hydrogenase, large subunit, C-terminal + Ribosomal protein L21, conserved site + YscD, cytoplasmic domain + Maltogenic Amylase, C-terminal + Alpha-L-arabinofuranosidase, C-terminal + Fructose-1,6-bisphosphatase + Prismane, alpha-bundle + Poly-beta-hydroxybutyrate polymerase, N-terminal domain + Conserved hypothetical protein CHP00255 + Bacteriophage HK97-gp10, putative tail-component + ECF transporter, substrate-specific component-like + Protein of unknown function UPF0301 + Flagellar hook-length control protein-like, C-terminal + Coenzyme F420:L-glutamate ligase-like domain + NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site + Pyruvate kinase, active site + NnrS + Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein + Acetate/propionate kinase + 4-oxalocrotonate tautomerase + Adenine phosphoribosyl transferase + Gamma-glutamylcyclotransferase, AIG2-like + UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD + FeS cluster insertion, C-terminal, conserved site + ATPase, AFG1-like + Peptidase S26A, signal peptidase I, serine active site + Acetate transporter GPR1/FUN34/SatP family + UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type + Flagellar motor switch protein FliG, N-terminal domain + D-3-phosphoglycerate dehydrogenase + Carboxyltransferase domain, subdomain A and B + Tyrosine-protein kinase, active site + D-aminopeptidase, N-terminal + Cytochrome P450, B-class + General secretion pathway protein K + Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal + Arylsulfotransferase, C-terminal + Photosynthesis system II assembly factor Ycf48/Hcf136-like domain + Ubiquinone biosynthesis hydroxylase UbiH/COQ6 + PFTB repeat + Domain of unknown function DUF5107 + TonB box, conserved site + DEAD2 + NarG-like domain + Bacterial alpha-L-rhamnosidase N-terminal + Pseudouridine-5'-phosphate glycosidase + Flagellar motor switch protein FliG, C-terminal + Galactose-1-phosphate uridyl transferase, C-terminal + Protein of unknown function DUF4432 + Galactose-1-phosphate uridyl transferase, class I + Acylphosphatase + Phasin + Mannose-6-phosphate isomerase, type I + Tyrosine recombinase XerD + Tip attachment protein J + Putative oxidoreductase/dehydrogenase, Rossmann-like domain + Protein of unknown function DUF368 + Lipoyl synthase, N-terminal + YbbR-like + CstA, C-terminal domain + ABC transporter, permease PhnE/PtxC + Manganese/iron superoxide dismutase, binding site + Inositol monophosphatase, SuhB + Adhesin B + Peptidase S1C, Do + Single Cache domain 2 + Fe-S metabolism associated domain, SufE-like + Protein of unknown function DUF990 + 2-isopropylmalate synthase, bacterial-type + Phenylalanine/histidine ammonia-lyases, active site + Peptidase C39, bacteriocin processing + Cytochrome b/b6, N-terminal + Domain of unknown functionDUF2779 + RecD helicase-like helix-hairpin-helix domain + Uncharacterised protein family UPF0313, N-terminal + Activator of Hsp90 ATPase homologue 1-like + eRF1 domain 2 + Protein of unknown function DUF1819, putative inner membrane + ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type + Nucleoside phosphorylase, conserved site + Coproporphyrinogen III oxidase, aerobic + YibE/F-like + Nitrilase/cyanide hydratase, conserved site + Phosphotransferase system, sugar-specific permease component + MORN variant + Glutamine-tRNA synthetase + Aspartate carbamoyltransferase regulatory subunit, C-terminal + H repeat-associated protein, N-terminal + DNA ligase, ATP-dependent, conserved site + Cytochrome c oxidase subunit II-like C-terminal + Conserved hypothetical protein CHP03960, radical SAM + TSCPD domain + LD-carboxypeptidase A, C-terminal domain + Outer membrane protein assembly factor BamA + tRNA modification GTPase MnmE + Microcompartment protein, bacteria + DNA recombination/repair protein RecN + 3-beta hydroxysteroid dehydrogenase/isomerase + 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase + Ribonuclease II/R, conserved site + Beta-propeller repeat + Type II bacterial toxin-antitoxin system, ParE-like toxin + 4-vinyl reductase, 4VR + Tumour necrosis factor-like domain + Chorismate mutase, AroH class + Ammonium transporter + Polyphosphate kinase 2, PA0141 + Murein tetrapeptide carboxypeptidase, N-terminal domain + Rhamnose/fucose mutarotase + Molybdate ABC transporter, substrate-binding protein + Cytochrome c oxidase, monohaem subunit/FixO + Uncharacterised membrane protein YitT + Resolvase, HTH domain + Porphobilinogen deaminase, dipyrromethane cofactor binding site + Sporulation stage II protein D, amidase enhancer LytB + Restriction endonuclease, type II, BamHI/BglIII/BstY + Deoxyhypusine synthase + Proton-dependent oligopeptide transporter family + Protein of unknown function DUF389 + TolB, N-terminal + Branched-chain amino acid transport, permease + Baseplate protein J-like + Protein of unknown function DUF951 + Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX + Oligopeptide transporter, OPT superfamily + Tetratricopeptide repeat-like domain + Uncharacterised protein family UPF0296 + Putative fluoride ion transporter CrcB + CRISPR-associated protein Cas4 + Putative cell wall binding repeat 2 + Rod shape-determining protein RodA + Terminase large subunit, Lambdalikevirus-type + N-acetylglucosaminyltransferase, MurG + Paraquat-inducible protein A + Protein of unknown function DUF481 + Acyclic terpene utilisation + CHAD domain + Redox-active disulphide protein 2 + Citramalate synthase + Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site + Putatuve nitroreductase, C-terminal, bacterial + Toluene tolerance Ttg2/phospholipid-binding protein MlaC + Electron transport complex, RsxE + Protein of unknown function DUF1464 + Uncharacterised protein family UPF0371 + FixG, C-terminal immunoglobulin-like domain + Nucleotide-binding protein, predicted, TIR-like domain + Senescence marker protein-30 (SMP-30) + RbsD-like domain + Pyruvate-flavodoxin oxidoreductase, EKR domain + Domain of unknown function DUF4062 + Positive regulator of sigma(E), RseC/MucC + Ribosomal protein L33, conserved site + Cryptochrome/DNA photolyase, FAD-binding domain + Major intrinsic protein + Flagellar M-ring C-terminal + Domain of unknown function DUF1565 + Carboxyltransferase domain, subdomain C and D + Translation elongation factor SelB, winged helix, type 2 + Glycoside hydrolase, family 65, central catalytic + Zinc finger/thioredoxin putative + Bacteriophage phiJL001, Gp84, N-terminal + Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal + ChrR-like cupin domain + Formiminotransferase catalytic domain + Polymorphic outer membrane protein repeat + MetA-pathway of phenol degradation, putative + Glutaminyl-peptide cyclotransferase + Uncharacterised protein family UPF0093 + Flagellar motor switch FliN/Type III secretion HrcQb + Deoxycytidine triphosphate deaminase, bacterial + Cytochrome c-type biogenesis protein CcmF + Transposase, IS30, conserved site + Neutral/alkaline non-lysosomal ceramidase, N-terminal + Cysteine peptidase, histidine active site + Glycoside hydrolase, family 2, active site + Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal + Small multidrug resistance protein family + Antitoxin ParD + Gram-negative bacterial TonB protein + Squalene cyclase, C-terminal + Death on curing protein + Replication initiator protein A + CHASE domain + Secretory protein YscJ/FliF + Domain of unknown function DUF3857 + Histidine biosynthesis HisG, C-terminal + Toxin-antitoxin system, YafQ-like toxin + Major facilitator superfamily associated domain + Nicotinate phosphoribosyltransferase family + Asparagine-tRNA ligase + Desulfoferrodoxin + Polyphosphate kinase N-terminal domain + 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase + Cytochrome-c3 hydrogenase, C-terminal + Pyruvate, phosphate dikinase + Flagellar motor switch protein FliG, middle domain + PD-(D/E)XK nuclease superfamily 4 + VCBS repeat + OST-HTH/LOTUS domain + Alpha-glycerophosphate oxidase, C-terminal + ANTAR domain + Phage head morphogenesis domain + Uncharacterised protein family UPF0276 + Putative HupE/UreJ protein + dCTP pyrophosphatase 1 + Flagellar motor protein MotA, conserved site + Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal + Heat shock protein HslU + AP endonuclease 1, conserved site + Glycosyl transferase family 39/83 + Conserved hypothetical protein CHP02231 + Peptidase S33 + ATP-dependent 6-phosphofructokinase, prokaryotic + Ureidoglycolate lyase domain + Protein of unknown function UPF0178 + Putative, 10TM heavy-metal exporter + O-methyltransferase, family 2 + DNA-directed DNA polymerase, family B, exonuclease domain + Endonuclease III + L-aspartate oxidase + Flagella basal body P-ring formation protein FlgA, C-terminal + Cytochrome c-type biogenesis protein CcmB + Type II secretion system protein H + Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase + Protein of unknown function DUF456 + Phosphoglucose isomerase, C-terminal + PhnA protein, C-terminal + Tetrapyrrole biosynthesis, glutamyl-tRNA reductase + ASCH domain + Glutamate--cysteine ligase, GCS2 + Serine acetyltransferase, N-terminal + Protein of unknown function DUF2284, metal-binding + Haemolysin A /rRNA methyltransferase TlyA + Major intrinsic protein, conserved site + Alpha-L-rhamnosidase C-terminal domain + HAD-superfamily hydrolase, subfamily IB, SerB1-like + Electron transport complex, subunit RnfD/RsxD + Amino acid permease/ SLC12A domain + 1,2-phenylacetyl-CoA epoxidase, subunit A/C + Lytic transglycosylase MltA, domain B + Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase + Ribosomal protein L36 + Fatty acid synthase + Thiamin pyrophosphokinase, catalytic domain + Peptide chain release factor 3, C-terminal + FeS cluster assembly SUF system, ATPase SufC + Protein of unknown function DUF2089 + Restriction endonuclease ThaI + Imidazolonepropionase + DMSO/Nitrate reductase chaperone + Acetyl-CoA carboxylase, biotin carboxylase + PrpF protein + Butyrate kinase + Transcriptional coactivator/pterin dehydratase + DNA polymerase III, delta prime subunit + Catalase core domain + L-2-amino-thiazoline-4-carboxylic acid hydrolase + Major capsid protein GpE + Nuclease SbcCD subunit D + Heat shock protein Hsp33 + Adhesion lipoprotein + Helicase Cas3, CRISPR-associated, core + Chaperonin ClpB + Squalene/phytoene synthase + TupA-like ATPgrasp protein + Serine proteases, trypsin family, histidine active site + 3-deoxy-D-manno-octulosonate cytidylyltransferase + Beta-lactamase hydrolase-like + Rare lipoprotein A + YcaO-like domain + MlaA lipoprotein + Plasmid replication-relaxation + Cytochrome ubiquinol oxidase subunit 2 + Beta galactosidase small chain/ domain 5 + Alpha-L-rhamnosidase, concanavalin-like domain + Peptidase M1, alanyl aminopeptidase, C-terminal + Mannitol dehydrogenase, N-terminal + Domain of unknown function DUF4277 + CbbQ/NirQ/NorQ, C-terminal + Protein of unknown function DUF1329 + 3-deoxy-8-phosphooctulonate synthase + Inosine-5'-monophosphate dehydrogenase + GTP-binding protein OBG, C-terminal + Flagellar transport protein FliP + Cytochrome c-type biogenesis protein CcmC + Calycin + Domain of unknown function DUF2281 + Malate synthase + Bacterial export protein family 3 + RND efflux system, outer membrane lipoprotein, NodT + D-ribose pyranase RbsD/L-fucose mutarotase FucU + Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal + Helicase-associated domain + Lytic murein transglycosylase + ABC transport permease subunit MlaE, Proteobacteria + HflC + Putative collagen-binding domain + Ribonuclease B, N-terminal OB domain + Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein + Cobalamin-independent methionine synthase MetE, C-terminal/archaeal + Carbonic anhydrase, prokaryotic-like, conserved site + DNA photolyase, N-terminal + Dihydrofolate reductase + Protein of unknown function DUF2905 + GerMN domain + Serine O-acetyltransferase + Rex DNA-binding, C-terminal domain + MORN motif + NnrU domain + Flagellar L-ring protein + Domain of unknown function DUF4340 + Putative adhesin + Alanine dehydrogenase + Electron transport complex, subunit RnfA/RsxA + Protein of unknown function DUF805 + Uncharacterised domain UPF0126 + Thymidine kinase, conserved site + Flavin-dependent halogenase + Bacterial Ig-like, group 2 + Divalent ion tolerance protein, CutA + Carbon storage regulator + Phthalate dioxygenase reductase + Histone acetyltransferase ELP3 + RES domain + Peptidogalycan biosysnthesis/recognition + Initiator Rep protein + Domain of unknown function DUF4124 + Disulphide bond formation protein DsbB-like domain + Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase + AP2/ERF domain + Phosphate binding protein + Peptidase M75, Imelysin + Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal + Flagellar hook capping protein + Peptidase M20C, Xaa-His dipeptidase + Acyl-CoA dehydrogenase, N-terminal, bacteria + Protein of unknown function DUF1667 + Glycerol kinase + Alkaline phosphatase + Glucose-6-phosphate dehydrogenase, active site + Bifunctional kinase-pyrophosphorylase + Sodium/sulphate symporter, conserved site + O-methyltransferase, family 3 + CcmE/CycJ protein + Protein of unknown function DUF1847 + Protein of unknown function DUF901 + FIST domain, N-terminal + L-asparaginase II + Adenine-specific methyltransferase, domain 2 + Putative glutamine amidotransferase type 2 + Transcription factor LuxR-like, autoinducer-binding domain + Adenine deaminase + HI0933 insert-like domain + Conserved hypothetical protein CHP02757 + Type I secretion membrane fusion protein, HlyD family + Transcriptional regulator, AbiEi 2 antitoxin, Type IV TA system + Trp repressor + Branched-chain amino acid transport, AzlD + Thiamin pyrophosphokinase, vitamin B1-binding domain + Uracil phosphoribosyl transferase + Peptidase S51 + Sugar/inositol transporter + KDPG/KHG aldolase, active site 2 + Glycoside hydrolase, family 37 + Disulphide bond formation protein DsbB/BdbC + Phosphotriesterase + Cytochrome C oxidase subunit II, transmembrane domain + Protein-PII uridylyltransferase, N-terminal + Adenosine/adenine deaminase + Microcystin LR degradation protein MlrC, C-terminal + Arsenate reductase + Hypothetical glycosyl hydrolase family 15 + RHS protein + RNA-binding protein Hfq + L-seryl-tRNA(Sec) selenium transferase + Electron transport complex, RnfB/RsxB + YCII-related + Galactokinase, conserved site + Copper centre Cu(A) + Uncharacterised protein family UPF0271, LamB/YcsF + Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal + Bacteriophage phiJL001, Gp84, C-terminal + Isopenicillin N synthase-like + Cytochrome oxidase maturation protein cbb3-type + 2-oxoglutarate dehydrogenase E1 component, N-terminal domain + Tagatose/fructose phosphokinase + Domain of unknown function DUF4433 + Urocanase + eRF1 domain 3 + Acid phosphatase/vanadium-dependent haloperoxidase-related + Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding + SUI1 domain + Glutathione peroxidase + Integrin alpha chain + L-lactate permease + D-serine dehydratase-like domain + Xylose isomerase + Arsenical pump membrane protein, ArsB + Topoisomerase C-terminal repeat + Pilus formation protein, N-terminal + Gluconate transporter + 3-dehydroquinate dehydratase type I + PaaX-like, C-terminal + Methanolan biosynthesis EpsI + Orotate phosphoribosyltransferase, bacterial + GTA TIM-barrel-like domain + Transketolase, bacterial-like + Tryptophan synthase, beta chain-like + FxsA cytoplasmic membrane protein + Ada DNA repair, metal-binding + RelB antitoxin/Antitoxin DinJ + Prokaryotic glutathione synthetase, N-terminal + Carbohydrate deacetylase YdjC-like + Coenzyme Q-binding protein COQ10, START domain + Glycosyl transferase, family 14 + Carboxylesterase, type B + Flagellar M-ring protein FliF + Domain of unknown function DUF2437 + Ribonuclease J, conserved site + Protein of unknown function DUF4416 + Alpha-L-fucosidase, C-terminal + Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain + PTR2 family proton/oligopeptide symporter, conserved site + Aspartate kinase, monofunctional class + Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal + MnmC-like methyltransferase + Thiaminase-2/PQQC + Ribosomal protein S16, conserved site + Siroheme synthase, central domain + Formyltetrahydrofolate deformylase + BNR repeat + Dual specificity phosphatase, catalytic domain + Protein of unknown function DUF998 + Aminoglycoside N(3)-acetyltransferase + Uncharacterised protein family UPF0210 + Microcystin LR degradation protein MlrC, N-terminal + Twin-arginine translocation protein TatB + Mannosyl-3-phosphoglycerate synthase + Heat shock protein Hsp33, N-terminal + Conserved hypothetical protein CHP02574, addiction module + NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 + Diadenylate cyclase CdaA + tRNA-dihydrouridine synthase, TIM-barrel, NifR3 + Pyridoxamine 5'-phosphate oxidase + Domain of unknown function DUF4007 + Membrane protein, 6-pyruvoyl-tetrahydropterin synthase-related domain + Transcription factor, NikR, nickel binding C-terminal + Penicillin-binding protein, OB-like domain + GTP-binding protein TypA + Flagellar hook-basal body complex protein FliE + Cyclophilin TM1367-like domain + CDC48 domain 2-like + Galactose oxidase, beta-propeller + Uncharacterised protein YjbR + Domain of unknown function DUF4372 + TM2 domain + ATP phosphoribosyltransferase, conserved site + Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like domain + Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal + Uracil-DNA glycosylase, active site + Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase + Heat shock protein Hsp33, C-terminal + Domain of unknown function DUF2075 + DAHP synthetase, class II + Protein of unknown function DUF463, YcjX-like protein + Transglycosylase-associated protein + Protein of unknown function DUF2460 + Ribosomal protein S21, conserved site + Type II secretion system GspD, conserved site + PHA accumulation regulator DNA-binding, N-terminal + Bacterial/plant glycogen synthase + JAB domain, prokaryotic + Bifunctional phosphoglucose/phosphomannose isomerase + Putative sugar-binding, N-terminal domain + Protein of unknown function DUF393 + Domain of unknown function DUF3473 + Haemerythrin, metal-binding domain + Proline-tRNA ligase, class IIa, archaeal-type + FdhE-like + DHHA2 domain + Small GTPase superfamily, ARF/SAR type + WHG domain + Flagellar protein FlgJ, N-terminal + DAK2 domain-containing protein YloV + C-methyltransferase + Indolepyruvate ferredoxin oxidoreductase, alpha subunit + Ribosomal RNA small subunit methyltransferase F, N-terminal + Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family + Protein of unknown function DUF1684 + Glycoside hydrolase family 31, N-terminal domain + Phosphoenolpyruvate carboxylase + Pirin, C-terminal domain + 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD + Endonuclease I + Protohaem IX farnesyltransferase + 3-isopropylmalate dehydratase, small subunit + Glycine betaine transport ATP-binding subunit + Spermidine synthase, tetramerisation domain + L-fucose isomerase, N-terminal-2 + ssDNA-binding transcriptional regulator + Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site + Stringent starvation protein B + FIST, C-domain + Glycosyl hydrolase family 98, putative carbohydrate-binding module + Peptidyl-arginine deiminase, Porphyromonas-type + Transcription factor CBF/NF-Y/archaeal histone domain + Phosphoglucosamine mutase, bacterial type + CRISPR-associated protein Cas7, subtype I-B/I-C + Protein of unknown function DUF350 + Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal + NapC/NirT cytochrome c, N-terminal + Glucose-6-phosphate isomerase, prokaryote + 6-hydroxymethylpterin diphosphokinase MptE-like + Ferric reductase transmembrane component-like domain + Glycoside hydrolase, family 5, conserved site + Thiamin pyrophosphokinase + Acyl-protein synthetase, LuxE + HB1/Asxl, restriction endonuclease HTH domain + Intracellular septation protein A + Phosphopentomutase DeoB cap domain + Hydroxymethylglutaryl-CoA reductase, bacterial-type + Alpha-amylase/branching enzyme, C-terminal all beta + Lactate racemization operon protein LarE + Flagellar hook protein FlgE + Integrase, integron-type + Toxin YoeB + N-acetylglucosamine-6-phosphate deacetylase + Phytanoyl-CoA dioxygenase + FRG domain + Putative inner membrane exporter, YdcZ + Protein of unknown function DUF484 + PspA/IM30 + Protein of unknown function DUF2971 + CcmH/CycL/Ccl2/NrfF family + AttH-like domain + Protein of unknown function DUF3768 + Structural maintenance of chromosomes protein, prokaryotic + Pyrimidine-nucleoside phosphorylase, conserved site + Protein of unknown function DUF554 + SepSecS/SepCysS family + Cytochrome b/b6, C-terminal + Protein of unknown function DUF4160 + Phage-like element PBSX protein, XkdF + DEAD/H associated + Exopolysaccharide biosynthesis protein YbjH + Haem-binding uptake, Tiki superfamily, ChaN + Peptidase C56, PfpI + Exosortase, EpsH + General secretion pathway protein G + Domain of unknown function DUF4352 + NADH-plastoquinone oxidoreductase, chain 5 + D-tagatose-bisphosphate aldolase, non-catalytic subunit GatZ/KbaZ + Cobyric acid synthase CobQ + Type-2 restriction enzyme BglII + DNA-directed DNA polymerase, family B, conserved site + Methionine biosynthesis MetW + VTC domain + Asparaginase/glutaminase, active site 1 + 7TM-DISM receptor, extracellular domain, type 1 + Nitrogen fixation protein FixH + Cell division protein FtsW + Phosphoserine phosphatase, domain 2 + V-ATPase proteolipid subunit + Heavy-metal resistance protein + Protein of unknown function DUF2188 + Beta-phosphoglucomutase hydrolase + AMP-activated protein kinase, glycogen-binding domain + Tetracycline transcriptional regulator, TetR-related, C-terminal + Glucosamine-6-phosphate isomerase, conserved site + PGF-CTERM archaeal protein-sorting signal + Ysc84 actin-binding domain + Protein of unknown function DUF1009 + DNA topoisomerase IV, subunit B, Gram-negative + Domain of unknown function DUF2235 + Protein of unknown function DUF1028 + TauD/TfdA-like domain + CDC48, N-terminal subdomain + Reductive dehalogenase + Sirtuin family, catalytic core small domain + Bacteriophage lambda, GpO, N-terminal + Protein of unknown function DUF4249 + Sulphate adenylyltransferase + Replication modulator SeqA, C-terminal DNA-binding domain + Ribonuclease II/ribonuclease R + Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase + Protein of unknown function DUF308, membrane + Cell wall hydrolase, SleB + Nudix hydrolase, N-terminal + Chromate resistance exported protein + Secretin/TonB, short N-terminal domain + Ureidoglycolate lyase + Conserved hypothetical protein CHP00251 + Phosphatidylserine decarboxylase, archaeal-type + Putative sensory transduction regulator YbjN + Peptidase M18 + Dethiobiotin synthase BioD + Fumarate reductase/succinate dehydrogenase, FAD-binding site + Rieske iron-sulphur protein, C-terminal + Transcription regulator YsiA, C-terminal + Bacteriophage phiJL001, Gp84 + Purine nucleoside phosphorylase I, inosine/guanosine-specific + Phosphodiester glycosidase + Inner membrane protein YedI + Sulphur oxidation protein SoxZ + Protein of unknown function DUF983 + 7 transmembrane helices usually fused to an inactive transglutaminase + Deoxyguanosinetriphosphate triphosphohydrolase, central domain + Transglutaminase-like cysteine peptidase, predicted + Cytochrome c, class II + Cytochrome c1 + HAD-superfamily hydrolase, superfamily IIB, MPGP + Glutamyl-tRNA reductase, conserved site + Na(+)-translocating NADH-quinone reductase subunit A + Domain of unknown function DUF1508 + Protein of unknown function DUF697 + Ubiquinone biosynthesis O-methyltransferase + NADH dehydrogenase, subunit C + Malic oxidoreductase + General secretion pathway, GspH + Protein of unknown function DUF900, hydrolase-like + Monothiol glutaredoxin-related + Drug resistance transporter Bcr/CmlA subfamily + Domain of unknown function DUF1553 + Bacteriophage T4, Gp19, tail tube + Glycosyl hydrolase family 32, C-terminal + Protein of unknown function DUF1788 + Flagellar hook-associated protein 1 + ABC-type transport auxiliary lipoprotein component + Phage portal protein, HK97 + DNA ligase D, 3'-phosphoesterase domain + Protein of unknown function DUF285 + Protein-tyrosine phosphatase, active site + Non-canonical purine NTP phosphatase/PRRC1 + Tail completion protein + Copper chaperone PCuAC + Sporulation stage V, protein S + Putative exodeoxyribonuclease 8, PDDEXK-like domain + Domain of unknown function DUF2147 + Sodium symporter small subunit, predicted + Formaldehyde-activating enzyme + Truncated hemoglobin + Protein of unknown function DUF2793 + Conserved hypothetical protein CHP02302, transmembrane + Restriction endonuclease, type I, HsdM + Mechanosensitive ion channel MscS, conserved site + 2-oxoacid:acceptor oxidoreductase, alpha subunit + Acetylserotonin O-methyltransferase, dimerisation domain + Cryptochrome/DNA photolyase class 1 + Protein of unknown function DUF3365 + Dynamin superfamily + Purine-cytosine permease + Peptidoglycan-associated lipoprotein + Catalase-peroxidase haem + Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 + Restriction endonuclease, type II, DpmII-like + Malectin + Hydroxyacylglutathione hydrolase, C-terminal domain + Protein of unknown function DUF847 + Protein of unknown function DUF1058 + Single cache domain 3 + Domain of unknown function DUF547 + Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain + Uncharacterised conserved protein UCP008505 + WxcM-like, C-terminal + Protein of unknown function DUF1893 + L-seryl-tRNA selenium transferase N-terminal domain + Flagellin/pilin, N-terminal + Endonuclease relaxase, MobA/VirD2 + Voltage-dependent anion channel + Cytochrome c oxidase cbb3 type, accessory protein FixG + RAD50, zinc hook + Triphosphoribosyl-dephospho-CoA protein + Integron-associated effector binding protein + Polyphosphate kinase + Protein of unknown function DUF1295 + Nucleotidyltransferase substrate binding protein, HI0074 + Protein FecR, C-terminal + Protein of unknown function DUF748 + TGF-beta, propeptide + Dihydroorotate dehydrogenase, class 2 + Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic + Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain + Glycerate kinase, flavodoxin-like domain + Threonyl-tRNA synthetase, editing domain, archaea + NIF system FeS cluster assembly, NifU-like + tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 + 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes + Domain of unknown function DUF4440 + Ribosomal protein L30, conserved site + Ig-like SoxY domain + Uncharacterised protein DUF2154, N-terminal + LSM domain, eukaryotic/archaea-type + Protein of unknown function DUF4956 + ABC transporter, phosphonate import, PhnC + DivIVA family + Domain of unknown function DUF4339 + HPP + Protein of unknown function DUF4389 + Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, N-terminal + Glycoside hydrolase family 10 domain + Domain of unknown function DUF4369 + BrnA antitoxin of type II toxin-antitoxin system + Adrenodoxin + Domain of unknown function DUF2061, membrane + Zinc finger, TFIIB-type + Gluconeogenesis factor + Nucleoside diphosphate pyrophosphatase + CRISPR-associated protein Cas6, C-terminal + Protein of unknown function DUF1285 + Domain of unknown function DUF1648 + RNA polymerase-binding transcription factor DksA + Glycerol-1-phosphate dehydrogenase + KduI/IolB isomerase + Glycosyl hydrolases family 1, N-terminal conserved site + Protein of unknown function DUF454 + Bacterial surface protein 26-residue repeat + Protein of unknown function DUF4177 + Phosphotransferase system, EIIC + Tn3 transposase DDE domain + Protein of unknown function DUF2911 + MtfA family + Dipeptide/tripeptide permease + HPr kinase/phosphorylase, C-terminal + Translation elongation factor, selenocysteine-specific + Aromatic-L-amino-acid decarboxylase + RNA polymerase sigma factor 70, non-essential domain + Glycogen debranching enzyme, C-terminal + Protein of unknown function DUF423 + Alpha-macroglobulin complement component + ACT-like domain + Ribosomal protein L11 methyltransferase + NifH/frxC family + Flagellar motor switch protein FliM + Tungstate ABC transporter, substrate-binding protein WtpA + Glycosyl-hydrolase 97, catalytic domain + Outer membrane protein, OmpW + Surfeit locus 1/Shy1 + DNA/RNA-binding protein Alba-like + DNA helicase, ATP-dependent, RecQ type, bacterial + Domain of unknown function DUF2202 + Glucose-1-phosphate thymidylyltransferase, long form + Uncharacterised protein family UPF0324, prokaryote + Domain of unknown function DUF2083,transcriptional regulator + Transcriptional regulator HTH-type, FeoC + Heat shock protein Hsp90, conserved site + Lipoate protein ligase, C-terminal + Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter + TfoX, N-terminal + Menaquinone biosynthesis enzyme + Nucleoside 2-deoxyribosyltransferase + Protein of unknown function DUF2927 + Flagellar hook-associated protein 2, N-terminal + NAD(P) transhydrogenase, alpha subunit, C-terminal + Flagellar hook-associated 2, C-terminal + Peptidase M1, alanyl aminopeptidase, Ig-like fold + Succinate dehydrogenase, cytochrome b556 subunit + Alpha-ketoglutarate-dependent dioxygenase AlkB-like + Post-segregation antitoxin CcdA + Arsenical-resistance protein Acr3 + Cell division protein FtsL + Transferase 1, rSAM/selenodomain-associated + Cysteine desulfurase, SufS + Pyridoxamine 5'-phosphate oxidase, conserved site + Type II restriction endonuclease EcoO109IR + Mevalonate kinase + ThiS, thiamine-biosynthesis + Malate dehydrogenase, type 3 + Heavy metal-associated domain, copper ion-binding + Transcription regulator HTH, Crp-type, conserved site + Protein of unknown function DUF4386 + Late embryogenesis abundant protein, LEA-14 + Protein of unknown function DUF3394 + Stage V sporulation protein G + Flagellin hook, IN motif + Alpha-2-macroglobulin, thiol-ester bond-forming + SurA N-terminal + Catalase, mono-functional, haem-containing + S-adenosylmethionine synthase + Cbb3-type cytochrome oxidase component + Peptidase family U32, C-terminal + Type III restriction/modification enzyme methylation subunit + Cysteine desulfurase NifS, bacterial/archaeal + Flavin monooxygenase-like + DNA primase/nucleoside triphosphatase, C-terminal + Dihydroneopterin aldolase + Tricorn protease, PDZ domain + Helicase XPB/Ssl2, N-terminal domain + Transposase-like, Mu, C-terminal + Cell division protein FtsE, ATP-binding + DNA ligase, ATP-dependent + Poly granule associated + Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal + SpoIIAA-like + Uncharacterised protein family UPF0216 + Uncharacterised protein family UPF0313, C-terminal + DNA polymerase III, delta subunit, C-terminal + Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain + Cell division coordinator CpoB, C-terminal + Xylulokinase + Clan AA aspartic peptidase, C-terminal + Domain of unknown function DUF4136 + Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site + Glycoside-hydrolase family GH114, TIM-barrel domain + 3(2),5 -bisphosphate nucleotidase, bacterial + Type-1 restriction enzyme R protein, C-terminal + Arginine-tRNA-protein transferase, C-terminal + RecT family + DNA damage-inducible protein DinB + ERCC4 domain + VRR-NUC domain + Fn3 associated repeat + Glutathione-specific gamma-glutamylcyclotransferase + ABC transporter, haem export, CcmA + Nitrogenase component 1, conserved site + HemY, N-terminal + PilC beta-propeller domain + Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, C-terminal + Type I secretion outer membrane protein, TolC + Flagellar basal-body rod protein FlgC + Protein of unknown function DUF2196 + Cobalt ECF transporter T component CbiQ + Uncharacterised domain CHP00451 + NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 + Cytochrome c, class IC + Domain of unknown function DUF2384 + Protein of unknown function DUF819 + Inosine/uridine-preferring nucleoside hydrolase, conserved site + Helicase SWF/SNF-related + Putative glycosyl hydrolase domain DUF4015 + Adenylosuccinate lyase PurB, C-terminal + tRNA(Ile)-lysidine synthase , substrate-binding domain + Glycosyl-hydrolase 97, N-terminal domain + Protein of unknown function DUF924 + Succinate dehydrogenase, hydrophobic membrane anchor + Cobalamin (vitamin B12) biosynthesis CbiX + Lysozyme domain + Concentrative nucleoside transporter C-terminal domain + Protein of unknown function DUF1499 + DNA-binding protein VF530-like + Uroporphyrinogen decarboxylase HemE + Glycoside hydrolase, family 28 + Fructose-bisphosphate aldolase, class-I + Electron transport complex, subunit RnfG/RsxG + Heparinase II, N-terminal + Xanthine/uracil permease + Fructose-1,6-bisphosphatase, active site + Protein of unknown function DUF932 + DNA polymerase III chi subunit, HolC + GpW/Gp25/anti-adapter protein IraD + Hly-III + DNA-directed DNA polymerase, family B, mitochondria/virus + Aconitase B, swivel + Protein of unknown function DUF2330 + Protein of unknown function DUF3422 + Rhamnose isomerase + CRISPR-associated protein, Cas6 + Restriction endonuclease, type II, AlwI + Ribosomal protein L7Ae/L30e/S12e/Gadd45 + Citrate lyase, alpha subunit + Domain of unknown function DUF1972 + 6-phosphogluconate dehydrogenase, decarboxylating + Holin of 3TMs, for gene-transfer release + S-adenosylmethionine decarboxylase proenzyme + Histidine ammonia-lyase + Penicillin-binding, C-terminal + Putative glutamine amidotransferase + Restriction endonuclease, type II, EcoRV + Peptidase C1B, bleomycin hydrolase + Protein of unknown function DUF1844 + Protein of unknown function DUF1194 + Terminase small subunit + Phosphotransferase system, HPr serine phosphorylation site + Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase + FR47-like + [NiFe]-hydrogenase, small subunit + Lipoprotein-releasing system transmembrane protein LolC/E + Protein of unknown function DUF2304 + Protein of unknown function DUF2125 + NADH-quinone oxidoreductase, chain I + 3-oxoacid CoA-transferase, subunit B + Methenyltetrahydromethanopterin cyclohydrolase + KTSC domain + DNA polymerase II large subunit DP2, N-terminal + Carbamate kinase + Glycosyl-hydrolase 97, C-terminal oligomerisation domain + Putative antitoxin + DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site + Domain of unknown function DUF3971 + L-2-Haloacid dehalogenase + Chaperonin TCP-1, conserved site + Quinone oxidoreductase/zeta-crystallin, conserved site + Pyruvate-flavodoxin oxidoreductase + Cdc6, C-terminal + Biotin synthase/Biotin biosynthesis bifunctional protein BioAB + SUF system FeS cluster assembly, SufB + Type 4 fimbrial biogenesis protein PilX, N-terminal domain + Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain + Archaeophage PsiM2, terminase large subunit + PH domain-like + Large-conductance mechanosensitive channel, conserved site + Stress responsive alpha-beta barrel + Zinc ribbon, NADH pyrophosphatase + Sirohaem synthase, dimerisation domain + Protein of unknown function DUF2219 + Domain of unknown function DUF815 + Protein of unknown function DUF938 + 5,10-methylenetetrahydrofolate reductase + RTX toxin determinant A + Putative GTP-binding controlling metal-binding domain + Ferredoxin, C-terminal + Asparaginase/glutaminase, active site 2 + Molybdate ABC transporter, permease protein + Protein of unknown function DUF1285, beta-roll domain + CpXC domain + Primase, C-terminal 2 + DNA gyrase inhibitor YacG + Flagellar assembly protein FliH/Type III secretion system HrpE + Type VI secretion protein, EvpB/VC_A0108, tail sheath + tRNA-hydroxylase MiaE + Protein of unknown function DUF1289 + YgfZ/GcvT conserved site + 1-acyl-sn-glycerol-3-phosphate acyltransferase + MoaD, archaeal-type + A/G-specific adenine glycosylase MutY + Lipoprotein SmpA/OmlA + Glycoside hydrolase family 65, C-terminal + ATP synthase protein I + ATP:guanido phosphotransferase, catalytic domain + Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family + 6-phosphogluconolactonase, DevB-type + Diacylglycerol glucosyltransferase, N-terminal + FMN-dependent alpha-hydroxy acid dehydrogenase, active site + Domain of unknown function DUF374 + Phage terminase large subunit, C-terminal + Na/Pi-cotransporter II-related/YqeW-like protein + Membrane complex biogenesis protein, BtpA family + Domain of unknown function DUF1549 + Jann4075-like domain + Probable chaperone CsaA + Protein of unknown function DUF2065 + Peptidase S46 + Protein of unknown function DUF2853 + Conserved hypothetical protein CHP02453 + UPF0014 family + RNA helicase HrpA, C-terminal + Alginate lyase domain + Cobyrinic acid a,c-diamide synthase CbiA + UDP-GlcNAc diphosphorylase/GlcNAc-1-P N-acetyltransferase, GlmU, bacterial-type + Protein of unknown function DUF3179 + Protein of unknown function DUF4238 + Protein of unknown function DUF92, TMEM19 + TPMT family + Helicase Helix-turn-helix domain + Concentrative nucleoside transporter N-terminal domain + Phosphorylase pyridoxal-phosphate attachment site + Macrocin-O-methyltransferase + Ubiquinol-cytochrome c reductase, iron-sulphur subunit + eRF1 domain 1/Pelota-like + Alpha-1,2-mannosidase, putative + Hydroxyacylglutathione hydrolase + Cobalt-precorrin-5B C(1)-methyltransferase CbiD + Phage tail collar domain + Cof family + Protein of unknown function DUF1538 + Phytase-like domain + Phosphoglycerate mutase 1 + Citrate synthase, type I + Peptidase S1A, chymotrypsin family + Domain of unknown function DUF5110 + Heat shock protein Hsp33, helix hairpin bin domain + Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y + Cytochrome P450, E-class, group I + DNA helicase Pif1-like + Homogentisate 1,2-dioxygenase + Protein of unknown function DUF2339, transmembrane + HEAT repeat + Glycosyl transferase, family 25 + PrkA AAA domain + Spermidine/putrescine ABC transporter, ATP-binding subunit + Protein of unknown function DUF882 + Chemoreceptor glutamine deamidase CheD + CDC48, domain 2 + RNA 3'-terminal phosphate cyclase type 1 + Urease alpha-subunit, N-terminal domain + Protein of unknown function DUF1302 + Protein of unknown function DUF166 + Protein of unknown function DUF211 + Transcription termination factor NusA, C-terminal duplication + Domain of unknown function DUF3343 + Predicted integral membrane protein DUF2189 + Transcription factor TFIIB, conserved site + Protein of unknown function DUF839 + Hydroxylamine reductase + Tetratricopeptide TPR-4 + Ornithine decarboxylase + Amino acid/polyamine transporter 2 + Esterase, PHB depolymerase + Domain of unknown function DUF403 + Phospholipase C/P1 nuclease domain + Bacterial Pleckstrin homology domain-related + Uncharacterised conserved protein UCP028069 + Glutaredoxin, GrxC + Autotransporter beta-domain + Sarcosine oxidase, gamma subunit + Protein of unknown function DUF4252 + Domain of unknown function DUF1858 + IMP dehydrogenase-related 2 + Beta propeller domain-containing family + Glycoside hydrolase, family 2, conserved site + Domain of unknown function DUF4994 + Disaggregatase-related repeat + Adrenodoxin, iron-sulphur binding site + Band 7/stomatin-like, conserved site + DivIVA domain + Hypothetical glycosyl hydrolase 6 + Alginate export domain + Membrane fusogenic activity + Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO + PocR domain + Domain of unknown function DUF1731 + Gas vesicle protein GvpA, conserved site + Putative DNA-binding domain, bacteria + Protein of unknown function DUF2797 + Primase, C-terminal 1 + Di-haem oxidoreductase, putative peroxidase + C4-dicarboxylate anaerobic carrier-like + C-type polyheme cytochrome OmcB + Protein of unknown function DUF4230 + Cytochrome c-type biogenesis protein CcmI + Gas vesicle protein GvpL/GvpF + Glucosamine-6-phosphate isomerase + Aspartate/other aminotransferase + D-glucuronyl C5-epimerase + Domain of unknown function DUF4105 + RepB plasmid partition + Hydantoinase/dihydropyrimidinase + Ribonuclease R + Tim44-like domain + Isopentenyl-diphosphate delta-isomerase, FMN-dependent + CRISPR-associated protein, Csd1-type + Initiation factor 2 associated domain, bacterial + WG containing repeat + Ribosomal protein S6, conserved site + Domain of unknown function DUF1989 + Phosphopentomutase + Domain of unknown function DUF4157 + Protein arginine methyltransferase NDUFAF7 + Protein of unknown function DUF952 + Protein of unknown function DUF4013 + Dimethylamine methyltransferase MtbB + GrpB/Dephospho-CoA kinase + Short chain fatty acid transporter AtoE + Bacterial mobilisation + Flagellar basal-body rod protein FlgB + TrkH potassium transport family + Arginine-tRNA-protein transferase, N-terminal + Pyridoxal phosphate phosphatase-related + Iron sulphur-containing domain, CDGSH-type + KDPG/KHG aldolase, active site 1 + Polyketide synthase, dehydratase domain + Ribokinase + Lipid A 3-O-deacylase-related + Putative C-S lyase + Nickel-dependent hydrogenase b-type cytochrome subunit + Lysine-2,3-aminomutase, C-terminal domain + Putative nucleotide-binding C-terminal domain + Periplasmic protein thiol:disulphide oxidoreductase DsbE + Bacteriophage SPP1, head-tail adaptor + Polyketide synthase, ketoreductase domain + Bacteriophage T5, Orf172 DNA-binding + LicD family + Proprotein convertase, P + Cell surface SprA + NADH pyrophosphatase-like, N-terminal + Methylmalonate-semialdehyde dehydrogenase + Protein of unknown function DUF1800 + ATPase, type III secretion system, FliI/YscN + 3-isopropylmalate dehydratase, large subunit, bacteria + Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA + Glycoside hydrolase family 18, catalytic domain + Uncharacterised protein family UPF0272 + Transcription regulator YcdC, C-terminal + Extensin-like, C-terminal + Nitrile hydratase alpha /Thiocyanate hydrolase gamma + Tol-Pal system, TolQ + Anthranilate synthase component I, PabB-like + Uridine kinase-like + Peptidase M10 serralysin, C-terminal + Scaffold protein Nfu/NifU, N-terminal + GSCFA + Solute-binding family 1, conserved site + Multicopper oxidase, type 2 + Ornithine aminotransferase + Anti-sigma-28 factor, FlgM + Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase + Glycoside hydrolase family 9 + Protein of unknown function DUF2232 + Gas vesicle protein GvpA + Domain of unknown function DUF2329 + Cytochrome c oxidase assembly protein CtaG/Cox11, domain + Uncharacterised protein family, glycosyl hydrolase catalytic domain + Domain of unknown function DUF4412 + Putative manganese efflux pump + 6-phosphogluconate-binding site + CobE/GbiG C-terminal domain + IMP biosynthesis enzyme PurP, C-terminal + ATP-dependent RNA helicase HrpB, C-terminal + Domain of unknown function DUF3333 + Amidase, carbamoylase-type + Flavinator of succinate dehydrogenase + Restriction endonuclease, type II, MjaI + Protein of unknown function DUF2752 + RNA methyltransferase TrmH, group 1 + Uracil-DNA glycosylase family 1 + SprT-like + Glycoside hydrolase, family 39 + Oxygen-independent coproporphyrinogen III oxidase HemN + Anti-sigma-28 factor FlgM, C-terminal + Protein of unknown function DUF1848 + Bacterioferritin + Protein of unknown function DUF5317 + Ferrochelatase, active site + Bacteriophage phiKZ, Orf197 + Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain + YaeQ + Flagellar protein FliS + Nucleoid-associated protein NdpA + Sulphate adenylyltransferase, large subunit + Multicopper oxidase, type 3 + Protein of unknown function DUF1704 + SMc04008-like domain + Ribosomal protein S1 + Flagellar basal-body rod FlgG + Putative rhamnosyl transferase + CRISPR-associated protein Cas8b + Urate oxidase N-terminal + Protein of unknown function DUF1178 + Cytochrome c oxidase assembly protein CtaG/Cox11 + Integral membrane protein TerC + CDP-diacylglycerol--serine O-phosphatidyltransferase + Glutaminase + Orc1/Cdc6-type DNA replication protein, archaea + PHB de-polymerase, C-terminal + Glutathione peroxidase active site + Uncharacterised protein family UPF0250 + Double Cache domain 3 + DNA-binding protein Dps + Cytochrome c oxidase cbb3-type, subunit III + Domain of unknown function DUF4430 + Flagellar biosynthesis protein, FliO + Peptidase M15B + Peptidase M13, N-terminal domain + Conserved hypothetical protein CHP02241 + Proline dehydrogenase PutA, domain II + Dihydrolipoamide succinyltransferase + Cytochrome C oxidase subunit IV, prokaryotes + Nicotinamide mononucleotide transporter PnuC + Bacteriophage lambda, GpH, tail tape measure, C-terminal + 5'(3')-deoxyribonucleotidase + Protein of unknown function DUF4446 + Pyrimidine 5-nucleotidase + Conserved hypothetical protein CHP02001 + Butirosin biosynthesis protein H, N-terminal + Uncharacterised protein family UPF0149 + Uncharacterised conserved protein UCP030820 + Toxic anion resistance + Protein of unknown function DUF1593 + Protein of unknown function DUF1064 + Oligosaccharide biosynthesis protein Alg14-like + Thiamin/hydroxymethyl pyrimidine-binding YkoF, putative + Domain of unknown function DUF4126 + Pilus assembly protein PilP + Peptidase M24, C-terminal domain + Aconitase B, HEAT-like domain + DNA-directed DNA polymerase, family B + Peptidase C70, AvrRpt2 + RNA polymerase sigma factor, FliA/WhiG + Autoinducer synthase + Winged helix DNA-binding domain + RarD protein + IstB-like ATP binding N-terminal + Gliding motility protein SprA N-terminal domain + Sodium:dicarboxylate symporter, conserved site + Non-haem dioxygenase N-terminal domain + Uncharacterised conserved protein UCP033101 + Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase + Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal + Protein YhcC-like + Host attachment protein + Integration host factor, beta subunit + Lysine-tRNA ligase + ComB-like + RNA polymerase sigma-70 ECF-like + Protein of unknown function DUF1223 + Domain of unknown function DUF4384 + DNA ligase, OB-like domain + Nitrile hydratase beta subunit domain + Nitrous oxide reductase accessory protein NosL + CDP-archaeol synthase + Uncharacterised peroxidase-related + Glucose-1-phosphate adenylyltransferase + ATP-citrate synthase, citrate-binding domain + Phage major tail protein TP901-1 + Peroxidase, active site + Nitrite reductase [NAD(P)H] small subunit, NirD + NIPSNAP + Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase + Vanillyl-alcohol oxidase/Cytokinin dehydrogenase C-terminal domain + Flagellar export FliJ + Peptide chain release factor 3 + Cytochrome c oxidase, subunit II + Na(+)-translocating NADH-quinone reductase subunit F + Virulence-associated E + Transport and Golgi organisation protein 2 + DMSO reductase anchor subunit (DmsC) + Sarcosine oxidase, delta subunit, heterotetrameric + Transcription regulator PadR, C-terminal + Sporulation protein YtfJ + Carbon monoxide dehydrogenase subunit G + Protein of unknown function DUF2204 + Dockerin type I repeat + Reductase, C-terminal + Purine nucleoside phosphorylase DeoD-type + MetA family + D-lyxose isomerase + SlyX + Sulphur relay, TusB/DsrH + Alcohol dehydrogenase, zinc-binding type 2 + Protein of unknown function DUF1643 + Glycoside hydrolase family 1, active site + Coenzyme A transferase binding site + Adenylyl cyclase CyaB + Protein of unknown function DUF4837 + Cytochrome c oxidase cbb3-type, subunit I + Tail specific protease, C-terminal + PepSY domain + Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase + Azospirillum phage Cd, Gp10 + Hydroxyethylthiazole kinase + Uncharacterised protein family UPF0158 + DNA-binding domain, IS481-type + Polysaccharide lyase + Abortive infection system protein AbiD/AbiF-like + Domain of unknown function DUF4325 + Protein of unknown function DUF3344 + Glycosyl hydrolase family 99 + Replication factor C, C-terminal + Molybdenum-pterin binding + Bacteriophage KVP40, Orf299 + Protein of unknown function DUF4442 + Intradiol ring-cleavage dioxygenase, C-terminal + Urease accessory protein UreD + Uncharacterised MFS-type transporter YbfB + Cell wall-active antibiotics response 4TMS YvqF + Glyoxalase-like domain + YheO-like + Bacterial Pleckstrin homology domain + YopX-like domain, beta barrel type + Conserved hypothetical protein CHP03663 + Peptidase M16C associated + Heme-NO binding + CRISPR-associated protein Cse1 + Transcriptional coactivator p15 (PC4) + Domain of unknown function DUF2126 + Domain of unknown function DUF4953 + Domain of unknown function DUF1738 + Transposase, IS1 + Integration host factor, alpha subunit + Abortive infection protein-like, C-terminal domain + Na(+)-translocating NADH-quinone reductase subunit C + Alpha-glucosidase, domain of unknown function DUF4968 + Molybdopterin converting factor, subunit 1 + Bacterial transglutaminase-like, N-terminal + Molybdenum cofactor biosynthesis protein B, proteobacteria + Transthyretin/hydroxyisourate hydrolase, superfamily + Conserved hypothetical protein CHP03980, redox-disulphide + Predicted 3'-5' exonuclease, PolB-like + Circularly permuted ATP-grasp type 2 + Resuscitation-promoting factor, domain of unknown function DUF348 + DNA polymerase 3, epsilon subunit + ApaG domain + Uncharacterised protein family UPF0164 + Succinate dehydrogenase, cytochrome b subunit, conserved site + Cytochrome b5-like heme/steroid binding domain + 2-keto-3-deoxy-galactonokinase + YtoQ family protein + RRXRR domain + 2-oxoglutarate dehydrogenase E1 component + Class III cytochrome C + Peptidase C15, pyroglutamyl peptidase I-like + Cobalt chelatase, CobT subunit + Beta-galactosidase, domain 4 + DHAP synthase, class 1 + Magnesium/cobalt transport protein CorA + Peptidase S12, Pab87-related, C-terminal + RLI1 + Uncharacterised protein family, zinc metallopeptidase putative + Uncharacterised protein family UPF0227/Esterase YqiA + Conserved hypothetical protein CHP02466 + FlgN-like protein + Undecaprenyl-phosphate glucose phosphotransferase, WcaJ + Tryptophan 2,3-dioxygenase + Dihydroxyacetone kinase, subunit L + Tol-Pal system beta propeller repeat-containing protein, TolB + Ribosome biogenesis GTPase RsgA, N-terminal + NlpC/P60 family, putative phage cell wall peptidase + Leucine rich repeat 5 + Transposase, Tn5-like, C-terminal + Cryptochrome/DNA photolyase class 1, conserved site, C-terminal + Aspartate carbamoyltransferase regulatory subunit, N-terminal + Bacterial Ig-like domain + Sec-independent periplasmic protein translocase, conserved site + Methyl-accepting chemotaxis protein, four helix bundle domain + Ribosomal RNA aminoglycoside-resistance methyltransferase + Domain of unknown function DUF4113 + CidB/LrgB family + Peptidase M20B, tripeptide aminopeptidase + Urease accessory protein UreF + Putative beta-barrel porin 2 + Phage gp6-like head-tail connector protein + EfeO-type cupredoxin-like domain + DNA primase, small subunit + Methyltransferase cognate corrinoid protein + RfaE bifunctional protein, domain II + Exodeoxyribonuclease I, C-terminal + Domain of unknown function DUF4392 + LPS export ABC transporter permease LptG + O-acetylhomoserine/O-acetylserine sulfhydrylase + Galactose-1-phosphate uridyl transferase, class I His-active site + Phage conserved hypothetical protein + Coenzyme F420:L-glutamate ligase + Para-aminobenzoate synthase, component I + Polyphosphate:nucleotide phosphotransferase, PPK2 + Protein of unknown function DUF4242 + Bacteriophage VT1-Sakai, H0018 + Urease, alpha subunit + Protein of unknown function DUF520 + RNA polymerase sigma factor RpoH, proteobacteria + SH3 domain protein + Toxin-antitoxin system, toxin component, HigB, putative + Uncharacterised protein family UPF0029, Impact, conserved site + DNA-binding protein Dps, conserved site + Fimbrial protein pilin + Hypothetical PA1492 domain + Ketoacyl-synthetase, C-terminal extension + Cell division topological specificity factor MinE + Gdt1 family + Proliferating cell nuclear antigen, PCNA, N-terminal + Ring-hydroxylating dioxygenase beta subunit + Aspartate--ammonia ligase + Precorrin-6x reductase + Histone deacetylase + GPI inositol-deacylase PGAP1-like + Peptidoglycan binding domain + GcrA cell cycle regulator + Fumarylacetoacetase, N-terminal + Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB + Capsule assembly protein Wzi + Transcriptional regulator PAI 2-type + HYR domain + ADP-heptose--LPS heptosyltransferase 2 + Orthogonal Bundle domain in ATP12 + Eukaryotic molybdopterin oxidoreductase + Peptidase M74, penicillin-insensitive murein endopeptidase + Delta-60 repeat + ABC-type thiamin-related transport system, permease component 1, predicted + Domain of unknown function DUF1456 + L-asparaginase, type I + Domain of unknown function DUF512 + Nickel/cobalt transporter, high-affinity + Phosphate-starvation-induced PsiE-like + RNA-binding, CRM domain + Protein of unknown function DUF1007 + Sodium/glutamate symport carrier protein GltS + Acyl carrier protein phosphodiesterase + Adenosylcobinamide amidohydrolase, CbiZ + Acetylornithine deacetylase ArgE + AttH domain + Hydrophobe/amphiphile efflux-1 HAE1 + Iron-sulphur-dependent L-serine dehydratase single chain form + Signal peptide, camelysin + Zinc finger, DksA/TraR C4-type, bacteria + Zona occludens toxin + Peptidase M1, alanyl aminopeptidase + 4-hydroxybenzoate polyprenyltransferase + Penicillin-binding protein activator LpoB + NB-ARC + Putative metal-binding domain of cation transport ATPase + TonB-dependent siderophore receptor + Biopolymer transport, TolR + YopX protein + Pyruvoyl-dependent arginine decarboxylase + Autotransporter-associated beta strand repeat + Moybdenum cofactor oxidoreductase, dimerisation + CHAP domain + Glutamine synthetase class-I, adenylation site + FO synthase, subunit 2 + Catalase immune-responsive domain + Type II secretion system protein J + HIRAN domain + Epimerase family protein SDR39U1 + Phosphoribosylaminoimidazole carboxylase, ATPase subunit + PrkA C-terminal domain + Protein of unknown function DUF4197 + Uncharacterised protein family PrgI + Septum formation inhibitor MinC, C-terminal + Anaerobic sulphatase maturase, radical SAM + Riboflavin kinase domain, CTP-dependent + 3-isopropylmalate dehydratase, large subunit + Haem exporter protein D (CcmD) + Adenine-specific methylase EcoRI + 3-dehydroquinate synthase + Bacteriophage Mu, GpT + Tellurite resistance methyltransferase TehB-like domain + Putative quorum-sensing-regulated virulence factor + Protein of unknown function DUF2721 + Glucokinase regulatory protein, conserved site + Prohibitin + Catalase active site + Pyruvoyl-dependent histidine/arginine decarboxylase, 3-layer sandwich domain + RNase L inhibitor RLI, possible metal-binding domain + Pectinesterase, catalytic + Protein of unknown function DUF4263 + Pheromone shutdown, TraB, bacterial/archaeal + FlaG protein + Protein of unknown function DUF455 + Phosphohistidine phosphatase SixA + Protein of unknown function DUF2267 + Invasion protein B + Gtr1/RagA G protein + Protein of unknown function DUF333 + Na(+)-translocating NADH-quinone reductase subunit D + Outer membrane autotransporter barrel + Tetrahydromethanopterin S-methyltransferase, subunit H/Methyltransferase Mtx, subunit H + Protein of unknown function DUF2254, membrane + CRISPR-associated protein, CT1975 + Harbinger transposase-derived nuclease domain + TspO/MBR-related protein + ThiC-associated domain + Phosphoenolpyruvate carboxykinase (ATP), conserved site + Luciferase family oxidoreductase, group 1 + Protein of unknown function DUF5309 + Glutathione synthetase, prokaryotic + Glucose-1-phosphate cytidylyltransferase + Erythromycin esterase + ATP binding protein MinD, bacterial-type + Diaminopimelate aminotransferase, DapL, Desulfovibrio-type + Thiamine-phosphate synthase ThiN + Urease, beta subunit + DNA/RNA-binding protein Alba + Peptidase C10, streptopain + Methyltransferase type 12 + Endonuclease MutS2 + Putative condensing enzyme FabH-related + ABC transporter, ATPase, putative + RecB family nuclease, TM0106, putative + Domain of unknown function DUF438 + Ribosomal RNA large subunit methyltransferase F-like + Copper homeostasis CutC domain + DNA helicase, RecD-like + Domain of unknown function DUF1611, P-loop + Head-to-tail connector protein, podovirus-type + Glutamine synthetase type III N-terminal + Biosynthetic peptidoglycan transglycosylase + Protein of unknown function DUF2490 + MOSC, N-terminal beta barrel + AbrB family + Protein of unknown function DUF349 + Aromatic amino acid hydroxylase + Formate dehydrogenase accessory protein + 2-phospho-L-lactate guanylyltransferase, CofC + Fibrillarin + Bacterial microcompartments protein, conserved site + Na(+)-translocating NADH-quinone reductase subunit E + Iron hydrogenase, small subunit + Aspartate-tRNA synthetase, type 2 + Cell division protein SepF/SepF-related + Putative ATP-binding cassette + IMP biosynthesis enzyme PurP, N-terminal + Abhydrolase, bacterial + UPF0234 N-terminal domain + Urease, gamma/gamma-beta subunit + Competence protein ComEC/Rec2 + GTP binding protein, second domain + Protein of unknown function DUF1631 + Bacillithiol biosynthesis BshC + PAAR motif + Domain of unknown function DUF4365 + Lipocalin-like domain + MTA/SAH nucleosidase + Bifunctional uridylyltransferase/uridylyl-removing enzyme + 2-amino-3-ketobutyrate coenzyme A ligase + Protein of unknown function DUF1365 + Phosphotransferase system, sorbose subfamily IIB component + Protein of unknown function DUF4202 + Thiosulfate oxidation carrier complex protein SoxZ + Protein of unknown function DUF3592 + Ribosomal RNA small subunit methyltransferase J + Acyl-ACP thioesterase + PhoR, single Cache-like domain + DNA primase large subunit, eukaryotic/archaeal + Protein of unknown function DUF2244, transmembrane + Methyltransferase Ppm1/Ppm2/Tcmp + TATA-box binding protein, conserved site + Protein of unknown function DUF937 + Branched-chain amino acid aminotransferase II + DNA-3-methyladenine glycosylase I + MltA-interacting MipA + Succinate dehydrogenase/fumarate reductase, flavoprotein subunit + Hemimethylated DNA-binding domain + Transcription regulator HTH, AraC, N-terminal + Protein of unknown function DUF1850 + Tail sheath protein, subtilisin-like domain + Phosphoglucosamine mutase, archaeal type + Protein of unknown function DUF2948 + PaaX-like, N-terminal + DNA topoisomerase I, catalytic core, eukaryotic-type + Domain of unknown function DUF427 + Secretion protein HlyD, conserved site + Transferase 2, rSAM/selenodomain-associated + Cupin domain of unknown function DUF985 + Nucleotidyltransferase 8 + Sulphate adenylyltransferase, small subunit + K+/H+ exchanger + Domain of unknown function DUF4190 + Aspartate dehydrogenase + Aconitase, putative + Tail sheath protein, C-terminal domain + Zinc finger, RanBP2-type + Protein of unknown function DUF1153 + Lipopolysaccharide export system protein LptA + Cytochrome C, Planctomycete + Ribonuclease Z/BN + Fatty acid cis-trans isomerase + Ubiquitin Mut7-C domain + Peptidase M10, metallopeptidase + Protein of unknown function DUF5305 + 7TM-DISM receptor, extracellular domain, type 2 + Aspartate-semialdehyde dehydrogenase, peptidoglycan lacking + Protein of unknown function DUF4292 + Ubiquinone biosynthesis protein Coq7 + Thymidylate synthase, active site + SUF system FeS cluster assembly, SufD + Glycogen debranching enzyme, bacterial and archaeal type, N-terminal + Uncharacterised protein family UPF0313 + Acrylyl-CoA reductase AcuI + Pseudouridine synthase TruD, conserved site + Penicillin-binding protein activator LpoA + Lipase, GDXG, putative histidine active site + Thioesterase + Phosphate acetyltransferase + PhnA protein, N-terminal + Protein of unknown function DUF2958 + Mannitol dehydrogenase + Uncharacterised conserved protein UCP020606 + Glycerate kinase, restriction-enzyme-like fold + Restriction endonuclease, type II, NotI + Histidinol phosphate phosphatase, HisJ + Alkyl sulfatase dimerisation domain + Domain of unknown function DUF4140 + RIO kinase, conserved site + Male sterility, NAD-binding + Queuosine precursor transporter QueT + Sodium/solute symporter, VC2705 subfamily + Uncharacterised conserved protein UCP032025 + Protein of unknown function DUF4954 + Phosphate propanoyltransferase + Protein of unknown function DUF2914 + Extradiol ring-cleavage dioxygenase LigAB, LigA subunit + Ribosomal RNA large subunit methyltransferase J + Domain of unknown function DUF4872 + Proliferating cell nuclear antigen, PCNA, C-terminal + Protein of unknown function DUF962 + Peptidase S10, serine carboxypeptidase + Type II secretion system, protein M + Transthyretin, thyroxine binding site + Transposase, Tn5-like, N-terminal + Protein of unknown function DUF4391 + S-layer family duplication domain + Big-1 (bacterial Ig-like domain 1) domain + p-Aminobenzoyl-glutamate transport protein AbgT + Abortive infection protein, AbiV family + Protein of unknown function DUF1287 + PHB accumulation regulatory + TniQ + Phosphotransferase system, IIA component fructose subfamily + YqaJ viral recombinase + DNA/RNA non-specific endonuclease + Glutamate--cysteine ligase + TIM-barrel domain, IGPS-like + Flagellar motor switch FliN + UPF0234/UPF0381 domain + Pyrimidine/purine nucleoside phosphorylase + Catalase haem-binding site + YidE/YbjL duplication + Ribonuclease T2-like + Cysteine-rich CPXCG protein + ZipA, C-terminal FtsZ-binding domain + Domain of unknown function DUF1828 + Isocitrate lyase + UDP-GlcNAc diphosphorylase/GlcNAc-1-P N-acetyltransferase, GlmU, archaeal-type + Putative metallopeptidase domain + Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA + Uncharacterised domain UPF0029, Impact, C-terminal + Alginate lyase 2 + ADF-H/Gelsolin-like domain + Protein of unknown function DUF2282, integral membrane + Alpha-acetolactate decarboxylase + ATPase MipZ + LTXXQ motif family protein + Restriction endonuclease, type II, BsuBI/PstI, C-terminal + Arginine decarboxylase + ATP12, ATP synthase F1-assembly protein + Alpha-amylase/4-alpha-glucanotransferase, C-terminal + Protein of unknown function DUF2130 + Amino acid synthesis, putative + Glutaredoxin-like domain + Ribbon-helix-helix domain + Uncharacterised conserved protein UCP032146 + Zinc-ribbon containing domain + NarX-like, N-terminal + Protein of unknown function DUF2804 + AAA ATPase, CDC48 family + Methyltransferase putative zinc binding domain + KipI family + Ribonucleotide reductase, class I , alpha subunit + Tail protein I + DNA topoisomerase VI, subunit B, transducer + Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit + Carbohydrate-selective porin OprB + Biotin-protein ligase, N-terminal + Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site + Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA + Protein of unknown function DUF3488 + VPLPA-CTERM protein sorting domain + tRNA sulfurtransferase ThiI + Holliday junction resolvase-related domain + Peptidase M73, camelysin + 4-hydroxybenzoyl-CoA thioesterase, active site + Cobalamin biosynthesis protein CobT VWA domain + Domain of unknown function DUF4832 + Thiol peroxidase conserved site + Alpha glucuronidase, N-terminal + Disaggregatase-related + Type IV pilus secretin PilQ + LrgA/CidA family + ABC transporter phosphate permease PstC, N-terminal domain + Type VI secretion system, VipA, VC_A0107 or Hcp2 + Type VI secretion system, TssF-like + Protein of unknown function DUF3127 + Tyrosine recombinase XerC + Ribonuclease D + Chemoreceptor zinc-binding domain + Choloylglycine hydrolase/NAAA C-terminal + Methylguanine DNA methyltransferase, ribonuclease-like domain + D-alanyl-D-alanine dipeptidase + Cytochrome c-type biogenesis protein CcmB, bacteria + Protein of unknown function DUF3520 + Bacterial Ig-like domain (group 3) + Domain of unknown function DUF402 + Succinyl-diaminopimelate desuccinylase, proteobacteria + Glycosyl hydrolase, family 88 + Protein of unknown function (DUF4381 + Group 4 capsule polysaccharide formation lipoprotein GfcB + Polyamine biosynthesis domain, conserved site + Domain of unknown function DUF2726 + Domain of unknown function DUF1592 + CbxX/CfqX + Isocitrate lyase/phosphorylmutase, conserved site + Uncharacterised protein YfbK, N-terminal + ATP-dependent Clp protease ATP-binding subunit ClpA + Aminoglycoside 6-adenylyltransferase + Ribonucleotide reductase class II vitamin B12-dependent, N-terminal domain + Cobalamin synthesis G, N-terminal + NifH/chlL conserved site + 4-hydroxyphenylpyruvate dioxygenase + Non-canonical purine NTP phosphatase + ABC transporter, ATP-binding protein, ChvD + Cobalamin-independent methionine synthase MetE, N-terminal + NADH dehydrogenase ubiquinone Fe-S protein 4, mitochondrial + Chemotaxis phosphatase CheX-like domain + MIT, C-terminal phospholipase D-like domain + Sucrose-phosphatase-like, N-terminal + Kinesin light chain + Abnormal spindle-like microcephaly-associated protein, ASH domain + Dihydrofolate reductase conserved site + CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit + Protein of unknown function DUF2237 + Membrane dipeptidase, active site + ParD-like antitoxin of type II bacterial toxin-antitoxin system + Flagellar biosynthesis protein FliQ + O-phosphoseryl-tRNA:Cys-tRNA synthase, archaea + Cytochrome c, class IE + Protein of unknown function DUF2155 + NmrA-like domain + Acetoacetate decarboxylase beta barrel domain + YmcC-like domain + Kynureninase + Sporulation stage V, protein R + Conserved hypothetical protein CHP02186-related, transmembrane + Galactosyltransferase, C-terminal + PDGLE domain + UreE urease accessory, N-terminal + Putative porin-10 + Protein of unknown function DUF2794 + Glycine dehydrogenase (decarboxylating) + Peptidase M3B, oligoendopeptidase-related clade 3 + (2R)-phospho-3-sulpholactate synthase, ComA + Protein of unknown function DUF1457 + LPS export ABC transporter permease LptF + Geranylgeranylglyceryl phosphate synthase + Glycoside hydrolase, family 27 + S-formylglutathione hydrolase + Domain of unknown function DUF5117 + Hypoxia induced protein, domain + Acetoacetyl-CoA reductase + Beta-lactamase, class-B, conserved site + Pyridoxal-phosphate binding site + Inositolphosphotransferase Aur1/Ipt1 + Type II secretion system GspE + Ribonuclease HII, helix-loop-helix cap domain + CheC-like protein + Antitoxin MqsA/HigA-2 + Protein of unknown function DUF3078 + Urease accessory protein UreE, C-terminal domain + Dihydroorotase homodimeric type + NTF2-like N-terminal transpeptidase + Histone-like protein H-NS + Protein of unknown function DUF655 + Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase + NADH:ubiquinone oxidoreductase intermediate-associated protein 30 + Histidine-specific methyltransferase, SAM-dependent + Lipocalin/cytosolic fatty-acid binding domain + Archaeal Nre, N-terminal + Thermonuclease active site + DNA topoisomerase VI, subunit A + tRNA methyltransferase, Trm1 + Alcohol dehydrogenase class III + Bromoperoxidase/chloroperoxidase, C-terminal + Ubiquitin-conjugating enzyme/RWD-like + Putative bacterial porin + Transcriptional regulator Spx/MgsR + Putative exonuclease, RdgC + Phosphonate metabolism protein PhnI + Protein of unknown function DUF1073 + Phosphatidylglycerol lysyltransferase, C-terminal + Zinc finger, CHCC-type + Domain of unknown function DUF418 + Chemotaxis phosphatase, CheZ + 2-phosphoglycolate phosphatase, prokaryotic + HPr(Ser) kinase/phosphorylase, N-terminal + DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type + Antitoxin MqsA + Domain of unknown function DUF4010 + WGR domain + Flagellar biosynthesis protein FlhA + Cobaltochelatase subunit CobS N-terminal domain + Ribosomal protein L37ae/L37e + Hydroxyisourate hydrolase + Xanthine dehydrogenase accessory protein XdhC + Polyhydroxyalkanoate synthesis repressor PhaR + KilA, N-terminal/APSES-type HTH, DNA-binding + Tyrosine/serine-protein phosphatase IphP-type + Methylglyoxal synthase + Protein of unknown function DUF4926 + 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate + Protein of unknown function DUF1476 + PQ-loop repeat + RfaE bifunctional protein, domain I + Sodium:galactoside symporter, conserved site + PDCD5-related protein + Domain of unknown function DUF4185 + PRD domain + Beta propeller repeat, Msarc-type + Head domain of trimeric autotransporter adhesin + Multicopper oxidase, type 1 + VWA-like domain + Gp5 N-terminal + NADH:ubiquinone oxidoreductase chain 4, N-terminal + Zinc finger, AN1-type + UDP-galactopyranose mutase, C-terminal + Uncharacterised protein family YdfA-immunity + Proteasome alpha-subunit, N-terminal domain + SecD export protein N-terminal TM domain + Urease accessory protein UreG + Domain of unknown function DUF4172 + Spo11/DNA topoisomerase VI, subunit A, N-terminal + Homoserine kinase + PhoPQ-activated pathogenicity-related protein, PqaA type + ATPase, type I secretion system, PrtD + Uncharacterised protein family YgbA + Domain of unknown function DUF4357 + Tol-Pal system-associated acyl-CoA thioesterase + Protein of unknown function DUF1761 + CDP-glucose 4,6-dehydratase + Protein of unknown function DUF47 + Type IV secretion system, VirB10 / TraB / TrbI + Probable phospholipid ABC transporter-binding protein MlaD + Protein of unknown function DUF3426 + Protein of unknown function DUF1275 + Quinone oxidoreductase PIG3 + Gluconate 2-dehydrogenase subunit 3 + YhcH/YjgK/YiaL family + Phosphoribulokinase + Protein of unknown function DUF3572 + Nitrate/nitrite sensing protein + Protein of unknown function DUF447 + L-rhamnose-proton symport, RhaT + Ammonium transporter, marine subtype + Proteolipid membrane potential modulator + Ni-containing CO dehydrogenase + DNA polymerase III, subunit gamma/ tau, C-terminal + BAAT/Acyl-CoA thioester hydrolase C-terminal + Protein of unknown function DUF1013 + Drug resistance transporter EmrB/QacA subfamily + Peptidyl-tRNA hydrolase II domain + Domain of unknown function DUF971 + Superoxide dismutase, copper/zinc binding domain + Uncharacterised protein family UPF0114 + Spo11/DNA topoisomerase VI subunit A + Ribosomal protein L31e domain + Ferredoxin thioredoxin reductase catalytic beta subunit + FHIPEP conserved site + DTW + Acyl-CoA dehydrogenase, C-termina, bacterial type + CsbD-like domain + Ta0600-like domain + Periplasmic pectate lyase + Ribonuclease P/MRP, subunit p29 + Phospholipase D, N-terminal + Domain of unknown function DUF3887 + NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 + Na(+)-translocating NADH-quinone reductase subunit B + Campylobacter phage CGC-2007, Cje0229 + Domain of unknown function DUF4982 + Glyoxalase I + Protein of unknown function DUF4125 + Domain of unknown function DUF861, cupin-3 + GYF-like domain + Precorrin-3B C17-methyltransferase domain + Two-component sensor kinase, N-terminal + ERCC3/RAD25/XPB helicase, C-terminal domain + Ribosomal protein L19/L19e + Domain of unknown function DUF1611_N, Rossmann-like domain + Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site + Conserved hypothetical protein CHP02300, FYDLN acid + Head decoration protein D + Protein of unknown function DUF3833 + Menbrane protein HflK, N-terminal + Domain of unknown function DUF4037 + RNA polymerase recycling, bacterial, C-terminal + Peptidase M20B, peptidase T-like + Protein of unknown function DUF99 + Protein of unknown function DUF3391 + Ribosome-associated, YjgA + tRNA intron endonuclease, N-terminal + Multicopper oxidase, copper-binding site + Domain of unknown function DUF1743 + Nicotinate phosphoribosyltransferase pncB-type + Bacterial TonB-dependent receptor + Protein of unknown function DUF1614 + Protein of unknown function DUF3276 + Fructosamine/Ketosamine-3-kinase + GPN-loop GTPase + Phosphotransferase system, mannose/fructose/sorbose family IID component + Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit + Flagellar hook-associated protein 3 + Formylmethanofuran dehydrogenase subunit C + Excalibur calcium-binding domain + Protein of unknown function DUF1294 + Protein of unknown function DUF2478 + Protein of unknown function DUF2484 + Protein of unknown function DUF4276 + Protein of unknown function DUF1674 + Peptidase M61, catalytic domain + tRNA nucleotidyltransferase, substrate binding + Urease nickel binding site + Domain of unknown function DUF4167 + Cytochrome c oxidase, subunit IV, bacterial aa3 type + Domain of unknown function DUF3298 + Protein of unknown function DUF3299 + XPG/Rad2 endonuclease + Aconitase/Iron-responsive element-binding protein 2 + Bacteriophage lambda NinG + Domain of unknown function DUF3495 + Deacetylase PdaC + Domain of unknown function DUF1588 + Glycosyltransferase 61 + Tetrahaem cytochrome domain + Spermidine/spermine synthases + Heptaprenyl diphosphate synthase component I + Flagellar biosynthetic protein FlhB + Phospholipase A1 + Methylene-tetrahydromethanopterin dehydrogenase, N-terminal + AGR-C-984p-like domain + PucR C-terminal helix-turn-helix domain + CRISPR-associated protein Cas7/Cst2/DevR + Uncharacterised conserved protein UCP029693 + Protein of unknown function DUF2148 + Nitrite reductase [NAD(P)H] large subunit, NirB + Restriction endonuclease, type II, CfrBI + Fibrobacter succinogenes major paralogous domain + tRNA-guanine transglycosylase, patch-forming domain C2 + Protein of unknown function DUF1116 + Protein of unknown function DUF3553 + Protein of unknown function DUF2141 + Putative PD-(D/E)XK phosphodiesterase (DUF2161) + Protein of unknown function DUF2852 + Probable protein kinase UbiB + D-glutamate cyclase + N-acetylmuramic acid 6-phosphate etherase MurQ + Transposase, Helix-turn-helix domain + Cytochrome c-type biogenesis protein CcsA + Uncharacterised conserved protein UCP028101 + Redox-sensitive transcriptional activator SoxR + Protein of unknown function DUF3871 + Flavodoxin-like + Phosphatidylserine decarboxylase + Anthrone oxygenase + Ceramide glucosyltransferase + Ribonuclease H2, subunit A + Mutator MutT + Peptidase T1A, proteasome beta-subunit + 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 1 + Regulator of ribonuclease activity A + Protein of unknown function DUF2889 + Putative metal-binding motif + MULE transposase domain + Urease active site + Type IV minor pilin ComP + Domain of unknown function DUF2249 + PhnA protein + DGC + Peptidase A31, hydrogenase maturation protease HycI + Pectic acid lyase + Cobalamin-dependent methionine synthase + Protein of unknown function DUF2334 + Ribosome maturation protein SBDS, C-terminal + Domain of unknown function DUF4174 + Zinc finger, TFIIS-type + Phosphoethanolamine transferase, N-terminal + Restriction endonuclease, type II, HinP1I + Protein of unknown function DUF411 + Protein of unknown function DUF1552 + Serine-threonine/tyrosine-protein kinase, catalytic domain + Sulfur oxidation c-type cytochrome SoxX + AMP nucleoside phosphorylase, N-terminal + Protein of unknown function DUF2800 + Protein of unknown function DUF3775 + Septum formation inhibitor MinC + Ribosomal protein S6e + Penicillin-binding protein 1C + tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal + Domain of unknown function DUF4158 + Diphthine synthase + Beta-phosphoglucomutase + Protein of unknown function DUF1467 + Phosphodiesterase YfcE, conserved site + Chromate transporter, long chain + Flagellum biosynthesis repressor FlbT + rRNA small subunit methyltransferase B + Coenzyme A transferase active site + Uncharacterised protein family UPF0229 + Mannosyl-3-phosphoglycerate phosphatase, thermophiles + XPG-I domain + AlgX/AlgJ, SGNH hydrolase-like domain + Domain of unknown function DUF1605 + Receptor L-domain + Integral membrane protein EMC3/TMCO1-like + Peptidase M2, peptidyl-dipeptidase A + Sensor N-terminal transmembrane domain + SoxAX cytochrome complex subunit A + Uncharacterised conserved protein UCP020408 + Signal transduction histidine kinase, HWE region + Domain of unknown function DUF3854 + Glutamyl-tRNA(Gln) amidotransferase subunit E + Peptidyl-tRNA hydrolase, PTH2 + Domain of unknown function DUF1722 + Proliferating cell nuclear antigen, PCNA + Flagellin, archaea + Domain of unknown function DUF2059 + Putative endonuclease, Z1 domain + Protein of unknown function DUF2080, transposon-encoded + Uncharacterised protein family UPF0201 + Holliday junction resolvase Hjc + O-phosphoseryl-tRNA(Cys) ligase + Peptide Chain Release Factor eRF1/aRF1, N-terminal + 5-nucleotidase + Glycoside hydrolase 35, catalytic domain + ST7 + Domain of unknown function DUF1957 + Elongation factor P--(R)-beta-lysine ligase + Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase + Proline iminopeptidase + Ryanodine receptor Ryr + Cardiolipin synthase + Ribosomal protein L31e + Ribosomal protein L32e + RNA ligase domain, REL/Rln2 + Peptidase M13, C-terminal domain + TfoX, C-terminal + DNA repair protein MmcB-like + Glycosyl hydrolase family 26 domain + Flavodoxin, long chain + Succinate dehydrogenase cytochrome b558 subunit + Cadherin + Phage tail tube protein, GTA-gp10 + Cellulase, Ig-like domain + Deoxyribodipyrimidine photolyase-related protein + Phenylacetic acid degradation B + Protein of unknown function DUF599 + Domain of unknown function DUF3369 + Protein of unknown function DUF3667 + Ribosomal protein S3Ae + Sodium:galactoside symporter + H-type lectin domain + Putative phage terminase, small subunit, P27 family + Protein of unknown function DUF116 + tRNA intron endonuclease, catalytic domain-like + DUF1653-like domain + Carbohydrate binding module family 6 + Branched-chain amino acid transport system II carrier protein + Protein of unknown function, Gp85/88 + Molybdate ABC transporter, ATP-binding protein + ImcF-related, N-terminal domain + Lysozyme inhibitor LprI, N-terminal + UDP-glucose 4-epimerase CapD, C-terminal domain + Uncharacterised protein family UPF0147 + Siphovirus Gp37-like protein + Flagellar basal-body rod FlgF + Protein of unknown function DUF373 + Anaerobic cobalt chelatase + Flagellar assembly protein A + Formylmethanofuran dehydrogenase, subunit B + Thermosome, archaeal + Protein of unknown function DUF2842 + Clostridium phage phiCTP1, Gp74 + Type VI secretion, TssG-like + Opacity-associated protein A + Domain of unknown function DUF1737 + Bacteriophage terminase, large subunit + Cysteine peptidase, asparagine active site + Haemolysin activator HlyB, C-terminal + Haemerythrin, iron-binding site + DmpG-like communication + GDSL lipase/esterase + Glycine zipper 2TM domain + Restriction endonuclease, type II, Tsp45I + Putative amidase domain + Amino acid adenylation domain + Glutamate synthase, NADH/NADPH, small subunit 2 + Lipase, GDXG, putative serine active site + Lytic transglycosylase, superhelical linker + ATP:guanido phosphotransferase active site + Beta-galactosidase C-terminal + Formylmethanofuran dehydrogenase, subunit A + Molybdenum cofactor guanylyltransferase + Putative selenium metabolism protein, YedE family + S1/P1 nuclease + Octaheme c-type cytochrome + Ribonuclease T2, His active site 1 + Domain of unknown function DUF3817, transmembrane + BRO N-terminal domain + Glycosyltransferase family 1, N-terminal + GTP-binding protein, orthogonal bundle domain + RnfH protein + Type II secretion system protein C, N-terminal + Vibrio phage ICP1, Orf50 + Glycoside hydrolase, family 24 + Isopentenyl-diphosphate delta-isomerase, type 1 + Protein of unknown function DUF3109 + MCM OB domain + Domain of unknown function DUF3696, C-terminal + Histone-like protein H-NS, C-terminal domain + Nascent polypeptide-associated complex NAC domain + NAD(P)H-quinone oxidoreductase subunit D/H + Protein of unknown function DUF2149 + Flagellar assembly factor FliW domain + Bacterial phosphonate metabolism, PhnH + Bacterial TniB + SPOC-like, C-terminal domain + Cell division protein ZapB + Protein of unknown function DUF1636 + Copper resistance protein D + Type VI secretion system, RhsGE-associated Vgr protein + Aromatic amino acid hydroxylase, C-terminal + Blood group Rhesus C/E/D polypeptide + Abhydrolase domain containing 18 + Phosphoserine aminotransferase, Methanosarcina-type + Acid phosphatase, class B-like + Ribosomal protein L19/L19e, domain 1 + Ribosomal protein L19/L19e, domain 3 + EcsC protein + Signal-peptide peptidase, presenilin aspartyl protease + tRNA (mo5U34)-methyltransferase-like + Flavoprotein WrbA-like + Succinate dehydrogenase, flavoprotein subunit + Protein of unknown function DUF359 + Ribosomal protein S4/S9, eukaryotic/archaeal + SLC26A/SulP transporter + DNA topoisomerase I, catalytic core, alpha/beta subdomain + Protein of unknown function DUF1150 + Domain of unknown function DUF357 + Domain of unknown function DUF4301 + Maltose/Cyclodextrin ABC transporter, substrate-binding protein + 4-oxalocrotonate tautomerase, Pseudomonas-type + Protein of unknown function DUF4932 + Ribonuclease HIII + CRISPR-associated protein, Csm2 Type III-A + Ribosome maturation protein SBDS, N-terminal + ABC transporter, urea, ATP-binding protein, UrtD + Phosphotransferase KptA/Tpt1 + Glycosyl transferase, family 11 + Lipoprotein LPP20-like + CUB domain + Flagellar assembly protein T, C-terminal + Alpha-amylase/4-alpha-glucanotransferase, central domain + Enhanced intracellular survival protein domain + Rhamnan synthesis F + SUF system FeS cluster assembly associated + Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase + Bacterial spore germination, immunoglobulin-like domain + Methyltransferase small, N-terminal + Precorrin-2 C(20)-methyltransferase domain + ATP-dependent helicase HrpB + Preflagellin peptidase, C-terminal + EthD domain + RNA polymerase, subunit H/Rpb5 C-terminal + Peptidase M16, middle/third domain + CagE, TrbE, VirB component of type IV transporter system, central domain + Glycosyl transferase family 10 + NusG, domain 2 + XPG N-terminal + Sarcosine oxidase, alpha subunit + Proteasome beta-type subunit, conserved site + Virulence-protein E, N-terminal + Ectoine synthase + Putative uroporphyrinogen-III C-methyltransferase HemX + Fumarate hydratase, class II + Selenium metabolism protein YedF + Gliding motility-associated protein GldM, N-terminal + Transthyretin, conserved site + Cob(I)alamin adenosyltransferase N-terminal domain + Peptidase S1B + Phosphopantoate/pantothenate synthetase + Uridylate kinase, archaeal/spirochete, putative + Protein of unknown function DUF2867 + Domain of unknown function DUF1987 + Flagellar biosynthesis protein FliR + Protein of unknown function DUF1853 + ATPase, type IV, pilus assembly, PilB + CRISPR-associated protein Cse3 + Sulphur relay, TusC/DsrF + Type II secretion system GspD + Phospholipase A2 domain + Kre9/Knh1 family + Hydrogenase nickel incorporation protein HypA/HybF, conserved site + Pyridoxamine 5-phosphate oxidase, FMN-dependent + Erythronate-4-phosphate dehydrogenase, dimerisation domain + Motility protein FimV, N-terminal + RNase P subunit p30 + Ribosomal protein S4e, central region + Glucodextranase-like, C-terminal + GLPGLI family protein + Ribosomal protein L5 eukaryotic/L18 archaeal + Ribulokinase + ABC transporter, urea permease protein UrtB, bacterial-type + (5-formylfuran-3-yl)methyl phosphate synthase + UDP-N-acetylglucosamine 4,6-dehydratase (inverting) + Putative beta-barrel porin-2, OmpL-like. bbp2 + Transcriptional repressor BetI + CRISPR-associated RAMP Csm3 + Glutathione peroxidase conserved site + Type II secretion system (T2SS), protein M subtype b + Peptidase C13, legumain + Protein of unknown function DUF4255 + Carboxylesterase type B, active site + Sarcosine oxidase subunit beta + Haem-binding domain + Ribosomal protein L19/L19e, domain 2 + Mannose-6-phosphate isomerase + Protein of unknown function DUF1217 + Ribosomal protein L26/L24, eukaryotic/archaeal + NADH-quinone oxidoreductase, chain G, C-terminal + Oligopeptide transporter OPT + Conserved hyptotheical protein CHP03862, flavoprotein, PP4765 + Type VI secretion system effector, Hcp + Flagellar assembly factor FliW + Protein of unknown function DUF424 + Plasmid conjugal transfer TrbL/VirB6 + Disulphide bond isomerase, DsbC/G, N-terminal + Methyltransferase MtrA/MtxA + Domain of unknown function DUF4173 + Anaphase-promoting complex subunit 4, WD40 domain + Reverse transcriptase, N-terminal domain + Arginine N-succinyltransferase AstA/AruG + 1,4-alpha-glucan-branching enzyme, GlgB + Curlin associated + Protein of unknown function DUF4282 + Type VI secretion protein, VC_A0114 + Protein transport protein SecG/Sec61-beta/Sbh + DNA topoisomerase I + Protein of unknown function DUF2849 + Acetoacetyl-CoA synthase + Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family + Archaeal Nre, C-terminal + FadR, C-terminal domain + Glycosyltransferase, DXD sugar-binding motif + Alpha amylase + Long-chain-fatty-acyl-CoA reductase, LuxC + Translation initiation factor IF2/IF5 + Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain + Methylglyoxal synthase, active site + Flavocytochrome c sulphide dehydrogenase, flavin-binding + Fe(II) trafficking protein YggX + Protein of unknown function DUF2798 + Ribosomal protein L15e core domain + Recombinase NinB + Protein of unknown function DUF560 + Uncharacterised domain, YlbE + NlpB/DapX lipoprotein + 3-hydroxybutyrate dehydrogenase + Protein of unknown function DUF4011 + Conserved hypothetical protein CHP00270 + Putative PD-(D/E)XK family member (DUF4420) + Sulphur oxidation, SoxY + Ribosomal protein L15e + Serine/threonine-protein kinase Bud32 + Bacillithiol biosynthesis deacetylase, BshB1 + Xanthine phosphoribosyltransferase + Orn/Lys/Arg decarboxylase, major domain + Sulphur relay, TusD/DsrE + DnaJ homologue, subfamily C, member 28, conserved domain + Protein of unknown function DUF4170 + JmjC domain + Prefoldin alpha-like + Phosphotransferase system, IIB component, type 1 + tRNA-splicing endonuclease + Homoserine O-succinyltransferase MetA + MASE1 + Uncharacterised GTP-binding protein, C-terminal + Glycoside hydrolase, family 1, beta-glucosidase + Conserved hypothetical protein CHP02653, peptidase S16 non-peptidase homologue + Protein of unknown function DUF1491 + 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase + Transcription regulator YbiH, C-terminal + Delta-1-pyrroline-5-carboxylate dehydrogenase 3 + Poly(R)-hydroxyalkanoic acid synthase, class I + Protein of unknown function DUF1348 + 3-hydroxyisobutyrate dehydrogenase + Glutaredoxin-like + Sensor histidine kinase NatK, C-terminal domain + Extracellular HAF + Gene transfer agent, major tail protein + CGI121/TPRKB + Protein of unknown function DUF898 + RNA methyltransferase domain + Translation initiation factor IF2/IF5, N-terminal + UDPGP family + Globin + Ribosome maturation protein Sdo1/SBDS + Phospholipase C/D + Uncharacterised protein family, inner membrane CreD + Potential Queuosine, Q, salvage protein family + Hydrolyase LeuD/DmdB, bacterial + Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase + Histidine phosphotransferase ChpT, C-terminal + Trans-2-enoyl-CoA reductase catalytic domain, putative + Transthyretin/hydroxyisourate hydrolase + Protein of unknown function DUF5343 + Exosome complex component, N-terminal domain + Glycosyl hydrolase, C-terminal (DUF3459) + KH domain protein, archaea + ABC transporter, urea, ATP-binding protein, UrtE + Superoxide dismutase, Nickel-type + EPS-associated transcriptional regulator, MarR family + Conjugal transfer TrbC/type IV secretion VirB2 + Bacteriophage phiNM3, A0EWY4 + mRNA interferase toxin MqsR + Protein of unknown function DUF3842 + Aldose 1-epimerase, conserved site + Ribosomal protein S17, archaeal/eukaryotic + Lipocalin family conserved site + Protein of unknown function DUF5103 + Poly-beta-hydroxybutyrate polymerase N-terminal + Protein of unknown function DUF4345 + Peptidase M24A, methionine aminopeptidase, subfamily 2 + YcgL domain + Transcription regulator TrmB, C-terminal + Protein of unknown function DUF3570 + Glutathione S-transferases, class Zeta + Nop2p + Protein of unknown function DUF3035 + Integrase SSV1, C-terminal + Ribonucleotide reductase small subunit, acitve site + Virulence factor domain + Protein of unknown function DUF3576 + Translation elongation factor IF5A + Cytoplasmic tRNA 2-thiolation protein 1 + Protein of unknown function DUF4199 + Protein of unknown function DUF445 + SseB protein N-terminal domain + Ribosomal protein L7Ae, prokaryotes + Ribosomal protein L22/L17, eukaryotic/archaeal + Cyclic-AMP phosphodiesterase, class-II + Coenzyme PQQ synthesis D, bacteria + Ribosomal protein S24e + Ku70/Ku80 beta-barrel domain + Peptidase S49, protease IV + Capsid protein, T4-like bacteriophage + Acetate-CoA ligase [ADP-forming], alpha domain + Peptidase C25, Ig-like domain + Major capsid protein Gp5 + HPr(Ser) kinase/phosphorylase + Domain of unknown function DUF5050 + 5-bromo-4-chloroindolyl phosphate hydrolysis protein + Ubiquinone biosynthesis protein COQ9 + Protein of unknown function DUF1045 + Toxin HigB-2 + ATPase terminase subunit, putative + LapD/MoxY, periplasmic domain + Domain of unknown function DUF4209 + Domain of unknown function DUF2357 + Protein of unknown function DUF2058 + Domain of unknown function DUF3772 + Protein of unknown function DUF881 + Selenoprotein, Rdx type + FTP domain + 2-phospho-L-lactate transferase + Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase + Cobalamin (vitamin B12) biosynthesis CobW + Probable transcription termination protein NusA, archaeal + Sulphate anion transporter, conserved site + YARHG domain + Transglutaminase-like domain + Type III secretion system flagellar brake protein YcgR, N-terminal + Domain of unknown function DUF305 + Uncharacterised conserved protein UCP012608 + D-cysteine desulfhydrase + Diphosphomevalonate decarboxylase + Outer membrane lipoprotein LolB + COQ9 + NUMOD4 + Isocitrate dehydrogenase kinasephosphatase + Hypothetical protein TM1410-related + Histone-lysine N-methyltransferase DOT1 domain + Malate synthase G + Peptidase T1A, proteasome beta-subunit, archaeal + AAA-ATPase-like domain + Fructose 1-phosphate kinase + Yjdj-type Gcn5-related N-acetyltransferase + Methylaspartate ammonia-lyase, C-terminal + Peptidase S55, SpoIVB + Ribosomal protein S8e/ribosomal biogenesis NSA2 + Uncharacterised domain UPF0702, alpha/beta domain + Copper ion binding protein + Phage conserved hypothetical protein, C-terminal + Malonyl-CoA decarboxylase, C-terminal + Bifunctional transglycosylase second domain + Protein of unknown function DUF779 + Protein of unknown function DUF3644 + Peptide chain release factor eRF1/aRF1 + Anti-sigma K factor RskA + Protein of unknown function DUF1697 + TrpR homologue YerC/YecD + Ribulose bisphosphate carboxylase, large chain, active site + Transcription regulator HTH, AraC- type, ligand binding domain-like + Type VI secretion system, RhsGE-associated Vgr family subset + Nucleoside-specific channel-forming protein, Tsx-like + Translation initiation factor IF6 + Ribosomal protein S19e + Succinate semialdehyde dehydrogenase + TnsA endonuclease, N-terminal + Flagellar motor stator, MotA + Flagellar FlaF + CRISPR-associated protein Cse2 + Phosphoserine aminotransferase + Translation initiation factor 2, alpha subunit, middle domain + Peptidase M4 domain + D-Lysine 5,6-aminomutase alpha subunit + PAN/Apple domain + NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal + Glycosyltransferase 2-like, prokaryotic type + CRISPR-associated protein Csm1 + HopJ type III effector protein + Fumarylacetoacetase + NADH ubiquinone oxidoreductase, F subunit + SaV-like + Translation elongation factor, IF5A, hypusine site + Protein of unknown function DUF1622 + Ribosomal protein L21e + BLUF domain + Coproporphyrinogen III oxidase, conserved site + Protein of unknown function DUF4270 + Selenium-dependent molybdenum hydroxylase system protein, YqeB family + Polyhydroxyalkanoate depolymerase + Domain of unknown function DUF5009 + tRNA-dihydrouridine(20/20a) synthase + Gliding motility-associated protein, GldL + Ribosomal protein S8e + Protein of unknown function DUF4387 + Prefoldin alpha subunit, archaea-type + Cas6b, C-terminal domain + Protein of unknown function DUF4835 + Protein of unknown function DUF3352 + DNA sulphur modification protein DndE + AP2-like integrase, N-terminal domain + F0F1-ATPase subunit, putative + Lipocalin, bacterial + N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA + Transcription elongation factor Spt5, archaeal + Protein SirB1, N-terminal + Metal-dependent protein hydrolase + Nitrous oxide reductase family maturation protein NosD + CRISPR-associated protein, TM1807 + Uncharacterised protein family UPF0753 + Cyanate hydratase + Polymerase A arginine-rich C-terminal domain + Cytochrome c-552/DMSO reductase-like, haem-binding domain + Protein of unknown function DUF3131 + SdiA-regulated + Xanthine dehydrogenase, molybdopterin binding subunit + Restriction endonuclease, type II, Bpu10I + Rhamnosyl O-methyltransferase/Cephalosporin hydroxylase + Formate dehydrogenase, gamma subunit + Domain of unknown function DUF4910 + Prefoldin beta-like + Signal recognition particle, SRP19 subunit + Protein of unknown function DUF2783 + TFIIEalpha/SarR/Rpc3 HTH domain + CRISPR-associated protein Cas1, HMARI/TNEAP subtype + Protein of unknown function DUF1328 + Benzoate transporter + Acetaldehyde dehydrogenase, C-terminal + DNA recombination/repair protein RadA + Type IV Pilus-assembly protein W + Protein of unknown function DUF2142, membrane + Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region + Ribosomal protein S4e, N-terminal + GNAT acetyltransferase YdfB-like + Capsule biosynthesis protein CapB + DNA topoisomerase I, DNA binding, eukaryotic-type + Capsule biosynthesis protein CapC + RNA polymerase sigma-70, Bacteroidetes type + Anti-sigma factor ChrR, putative + Thermostable hemolysin + Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr + Translation initiation factor 2, alpha subunit + Glycosyl transferase, family 8 + Restriction endonuclease, type II, EcoRII, C-terminal + MobA/MobL protein + Spi protease inhibitor + Protein of unknown function DUF2271 + RNA polymerase Rpb7, N-terminal + ROSMUCR transcriptional regulator + HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB + HAD-superfamily hydrolase, subfamily IIA, hypothetical 3 + Repressor KorB domain + UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing + Outer membrane lipoprotein carrier protein LolA, Proteobacteria + Protein of unknown function DUF2178, transmembrane + Ribosomal protein S13/S15, N-terminal + Glycosyl hydrolase family 30, beta sandwich domain + RNA polymerase Rpb2, domain 4 + RNA polymerase Rpb2, domain 5 + UV-endonuclease UvdE + Peptidase S49, N-terminal proteobacteria + Glycoside hydrolase, chitinase active site + Peptidase M4, C-terminal + BCCT transporter, conserved site + Protein of unknown function DUF420 + Transcription elongation factor Spt5, NGN domain + Proline dehydrogenase PutA, domain I + Protein of unknown function, OB-fold-containing + Protein of unknown function DUF2750 + Aspartate transcarbamylase regulatory subunit + PuuE allantoinase/chitin deacetylase 1 + Co-chaperone HscB, C-terminal oligomerisation domain + Nuclease SbcCD subunit D, C-terminal domain + Homoserine/serine acetyltransferase MetX-like + Nop domain + Diphthamide synthesis DPH1/DPH2 + dUTPase/dCTP pyrophosphatase + PrcB C-terminal domain + Flotillin, C-terminal domain + Guanine deaminase + Phosphotransferase system, fructose-specific IIB subunit + Phenylacetate-CoA oxygenase, PaaJ subunit + Protein of unknown function DUF4438 + Restriction endonuclease, type II, XcyI + Uncharacterised protein family AroM + Domain of unknown function DUF1338 + Translation initiation factor 2, alpha subunit, C-terminal + Elongation factor Tu-type domain + Filamentous haemagglutinin, N-terminal + RloB-like protein + Peptidoglycan-binding protein, CsiV + Cysteine-rich small domain + Uncharacterised conserved protein UCP025560 + Anaphase-promoting complex subunit 5 + Protein of unknown function DUF1249 + Ribosomal protein S27a + Trans-2-enoyl-CoA reductase + Protein of unknown function DUF3568 + Regulator of ribonuclease activity B domain + Chorismate mutase, bacteria + Protein of unknown function DUF3584 + Uncharacterised protein family UPF0274 + Domain of unknown function DUF4111 + 3'-5' exoribonuclease Rv2179c-like domain + Peptidase C15, pyroglutamyl peptidase I + DNA-directed RNA polymerase, M/15kDa subunit + Blue (type 1) copper domain + Domain of unknown function DUF5011 + GTP-binding protein, ribosome biogenesis + DNA-directed RNA polymerase, phage-type + Malonate decarboxylase/citrate lyase acyl carrier protein + Methyl-coenzyme M reductase, alpha/beta subunit, domain 2, C-terminal + Methylaspartate ammonia-lyase, N-terminal + ImpA, N-terminal + Conserved hypothetical protein CHP02243 + Ribosomal protein L37ae + Restriction endonuclease, type II, AvaI/BsoBI + Invasion gene expression up-regulator, SirB + CRISPR-associated protein, Cas02710 + SET domain + tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY + Translation initiation factor 2, gamma subunit, C-terminal + Choline sulfatase enzyme C-terminal domain + Nitrate transport ATP-binding subunit C/D + B-box-type zinc finger + Pentatricopeptide repeat + Protein of unknown function DUF1786, putative pyruvate format-lyase activating enzyme + Ribonuclease P/MRP protein subunit + Translocon Sec61/SecY, plug domain + Uncharacterised conserved protein UCP004929, methanogenesis + DNA primase DnaG, DnaB-binding domain + Ribosomal protein L7Ae/L8/Nhp2 family + RsbT co-antagonist protein RsbRD, N-terminal domain + KH domain, archaeal + Arginine repressor + Uncharacterised protein family, Ynq1 + Protein of unknown function DUF3822 + DNA integrity scanning, DisA, linker region + Exostosin-like + Protein of unknown function UCP009160 + Indolepyruvate ferredoxin oxidoreductase, beta subunit + Transposase Tn5, dimerisation + Methylamine utilisation protein, MauE + Glycosyl hydrolase family 63, C-terminal + Domain of unknown function DUF676, lipase-like + Siphovirus-type tail component + MerC mercury resistance protein + Glycosyl hydrolase family 66 + CRISPR-associated protein Csh2 + Protein of unknown function DUF3578 + PrlF antitoxin + Glycoside hydrolase, family 4, conserved site + Protein of unknown function DUF3810 + YbgF, trimerisation domain + RNA polymerase II, Rpb4 + Ribonuclease, PIN domain + Glucan biosynthesis, periplasmic, MdoG C-terminal + Ethanolamine ammonia lyase large subunit + Squalene/phytoene synthase, conserved site + Extradiol ring-cleavage dioxygenase, class I /II + tRNA 2-selenouridine synthase + Phosphotransferase system EIIB, cysteine phosphorylation site + Maltose/galactoside acetyltransferase + Transcription elongation factor GreB + Bestrophin/UPF0187 + tRNA ribose 2'-O-methyltransferase, aTrm56 + Ribosomal protein S5, eukaryotic/archaeal + DNA-directed RNA polymerase, RBP11-like dimerisation domain + 4-hydroxybenzoate polyprenyltransferase-related + Protein DJ-1 + Lipase, GDSL, active site + Thioesterase, putative + Ribosomal protein L6P, archaea + DNA N-6-adenine-methyltransferase + Protein of unknown function DUF3047 + Ribonuclease H1, N-terminal + Tryptophanase, conserved site + Protein of unknown function DUF421 + Recombination endonuclease VII + SdpI/YhfL protein family + Domain of unknown function DUF1585 + Actin family + 1,2-phenylacetyl-CoA epoxidase, subunit C + CTAG/Pcc1 family + Chalcone isomerase, 3-layer sandwich + YHYH domain + DNA-directed RNA polymerase, subunit E/RPC8 + N(4)-bis(aminopropyl)spermidine synthase, C-terminal + Mercuric transport protein periplasmic component/copper chaperone CopZ + Protein of unknown function DUF3427 + Protein of unknown function DUF2799 + Poly-gamma-glutamate system protein + Polynucleotide kinase 3 phosphatase + Arginine repressor, C-terminal + (Na+)-NQR maturation factor NqrM + Lipid A biosynthesis, N-terminal + Methyl-coenzyme M reductase, alpha subunit, N-terminal subdomain 2 + tRNA wybutosine-synthesis + Smg + Domain of unknown function DUF3492 + DNA topoisomerase I, domain 1 + SusD-like + Putative threonine/serine exporter + Nitrate reductase chaperone, NarJ + Na+/H+ antiporter NhaB + Elongation factor P hydroxylase + Mitochondrial fission protein ELM1-like + RNA-binding protein YhbY + Domain of unknown function DUF4055 + Uncharacterised protein family, phage tail-like + Ribosome biogenesis protein, C-terminal + Ribosomal protein S17e + Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic + Outer membrane lipoprotein Slp + DNA-3-methyladenine glycosylase AlkA, N-terminal + Transposase (putative), YhgA-like + Uncharacterised conserved protein UCP029215 + Translation initiation factor 1A (eIF-1A) + L-fucokinase + Cytidine/deoxycytidylate deaminase, zinc-binding domain + CRISPR-associated protein Cas2 subtype + CRISPR pre-crRNA endoribonuclease Cas5d + Competence-induced protein CoiA-like + Peroxidases heam-ligand binding site + ATP-dependent RNA helicase Ski2, C-terminal + GspL periplasmic domain + SapC + Glutamyl-tRNA(Gln) amidotransferase subunit D + UDP-2,3-diacylglucosamine hydrolase + Urea ABC transporter, substrate-binding protein UrtA-like + ABC transporter, ATP-binding/permease protein + Protein of unknown function DUF1189 + Ribosomal protein S28e + Tol-Pal system, TolA + NAD(P) transhydrogenase, alpha subunit + Ribosomal protein S23, eukaryotic/archaeal + Domain of unknown function DUF4214 + Protein of unknown function DUF4390 + Addiction module killer protein, predicted + O-succinylhomoserine sulfhydrylase + DNA polymerase III subunit delta, C-terminal + FlgD Tudor-like domain + Domain of unknown function DUF927 + Dyskerin-like + Proteinase inhibitor I78 + Hydrogenase/Urease accessory protein HupE/UreJ protein + Phosphonate metabolism PhnG + Prolyl-tRNA editing protein, YbaK/EbsC + Protein of unknown function DUF2877 + Ribosomal protein L13, eukaryotic/archaeal + Glycosyl hydrolase family 30, TIM-barrel domain + N-ATPase, AtpR subunit-like + Type II secretion system protein M, periplasmic domain + Multicopper oxidases, conserved site + Ralstonia phage RSL1, Orf186 + Cyanate lyase, C-terminal + Translin family + Thiaminase II + Ribosomal protein S19A/S15e + L-threonine-O-3-phosphate decarboxylase + L-arabinose isomerase, C-terminal + Helical and beta-bridge domain + Uncharacterised protein family UPF0270 + Peptidase U32, collagenase + Protein of unknown function DUF2959 + Translation release factor pelota + Protein of unknown function DUF2326 + Sulphotransferase Stf0, domain + Phosphoesterase + Nitrate reductase, gamma subunit + Carbohydrate binding module family 11 + Cytidylate kinase, putative + Type I secretion C-terminal target domain, VC_A0849 subclass + Protein of unknown function DUF63 + Phage tail assembly chaperone protein, TAC6 + Conserved hypothetical protein CHP02687 + Thymidine phosphorylase/AMP phosphorylase + Anti sigma-E protein RseA, N-terminal + Transcription factor S + Domain of unknown function DUF3641 + ImcF-related + Cyclo-malto-dextrinase, C-terminal + Signal transduction response regulator, propionate catabolism activator, N-terminal + NADAR + Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic + Protein of unknown function DUF2066 + Protein of unknown function DUF2069, membrane + TRAP transporter T-component + Protein of unknown function DUF4154 + Putative Actinobacterial Holin-X, holin superfamily III + Decarboxylase MfnA, archaea + Histidinol-phosphatase + Protein of unknown function DUF2950 + L-threonine dehydratase biosynthetic IlvA + Putative metallopeptidase + Protein of unknown function DUF4271 + Proto-chlorophyllide/chlorophyllide reductase, C-terminal + Uncharacterised protein family UPF0283 + Protein of unknown function DUF1415 + 2-methylcitrate synthase/citrate synthase type I + AMP nucleosidase + Ribosomal protein L12, archaea + Protein of unknown function DUF2795 + SOUL haem-binding protein + Endosomal/lysomomal potassium channel TMEM175 + Carbohydrate kinase, thermoresistant glucokinase + Glutamate synthase, NADH/NADPH, small subunit 1 + CRISPR-associated protein Cas1, ECOLI subtype + Gliding motility-associated lipoprotein, GldH + Alpha/beta hydrolase fold-5 + ArsR-type transcription regulator, HTH motif + Protein of unknown function DUF1269, membrane associated + Glycyl radical enzyme, PFL2/glycerol dehydratase family + Chorismate--pyruvate lyase + Phosphoenolpyruvate carboxylase, His active site + Copper binding periplasmic protein CusF + RecBCD enzyme subunit RecD + Protein of unknown function DUF371 + 2,4-diaminobutyrate 4-transaminase + Protein of unknown function DUF434 + Domain of unknown function DUF2489 + Protein of unknown function DUF2306, membrane + Hydroxymethylglutaryl-coenzyme A synthase, N-terminal + Cytochrome c552 + Type VII secretion system ESAT-6-like + Cytochrome c, class III + Nucleotidyltransferase, predicted + Flap structure-specific endonuclease, archaea + Protein of unknown function DUF3010 + Enoyl reductase FAD binding domain + Phosphotransferase system, fructose IIC component + Ammonia monooxygenase/particulate methane monooxygenase, subunit C + Exopolysaccharide synthesis, ExoD + SusE outer membrane protein + Acetaldehyde dehydrogenase + Protein of unknown function DUF2092, periplasmic + Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype + Fructose-bisphosphate aldolase, class II, Calvin cycle subtype + Nicotinamide-nucleotide adenylyltransferase, archaeal type + GspL, cytoplasmic actin-ATPase-like domain + CHASE4 + Protein of unknown function DUF2784 + Mth639-like domain + Ribosomal protein L44e + Protein of unknown function DUF2160, transmembrane + Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type + ADP-L-glycero-D-manno-heptose-6-epimerase + Histidine kinase BarA, N-terminal + Protein of unknown function DUF4290 + Double-strand break repair protein AddB + Putative sodium bile acid cotransporter + Protein of unknown function DUF3536 + Protein of unknown function DUF2796 + Uncharacterised protein family 14.7kDa + Phenylacetic acid degradation protein PaaD + ABC transporter, urea, permease protein, UrtC + Protein of unknown function DUF4019 + AraC-type transcription regulator, ligand-binding domain + Protein of unknown function DUF935 + Isocitrate dehydrogenase NADP-dependent + Inner membrane protein YebE + Protein of unknown function DUF4254 + Arginine repressor, DNA-binding domain + MucB/RseB, N-terminal + Pseudaminic acid biosynthesis, PseI + Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ + 2-hydroxy-3-oxopropionate reductase + Conserved hypothetical protein CHP02058 + Gliding motility associated protein GldN + GlyGly-CTERM domain + Protein of unknown function DUF1805 + Transcriptional regulator AbiEi antitoxin, N-terminal domain + Putative selenium-dependent hydroxylase accessory protein YqeC + DNA topoisomerase I, zinc ribbon-like, bacterial-type + Protein of unknown function DUF3445 + Thiosulfohydrolase SoxB + S-layer protein, C-terminal + Protein of unknown function DUF2878 + Inositol 2-dehydrogenase + Ribosomal protein S6e, conserved site + Serine proteases, trypsin family, serine active site + Mycobacteriophage D29, Gp61 + Uncharacterised protein family HI1736/YgjV + Selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family + DNA polymerase beta, palm domain + GHMP kinase group 1 + Putative glutamate--cysteine ligase YbdK + Ribosomal protein L7Ae, archaea + High mobility group box domain + PhnB-like + Protein of unknown function DUF2891 + Coenzyme PQQ biosynthesis protein C + Gliding motility-associated protein GldM, C-terminal + Protein of unknown function DUF1699 + CRISPR-associated protein, CasD + Peptidase U9, T4 prohead protease + Protein of unknown function DUF4407 + Signal transduction histidine kinase, P2 response regulator-binding + Protein of unknown function DUF1576 + Ribosomal protein L30, central domain, archaeal type + Aminodeoxychorismate lyase, class IV + Cyclomaltodextrinase, N-terminal + Isochorismatase + Ribosomal protein L3-specific, glutamine-N5-methyltransferase + Threonine/Serine exporter, ThrE + Receptor, ligand binding region + ATP phosphoribosyltransferase regulatory subunit + Prefoldin subunit beta + Vitamin K-dependent gamma-carboxylase + Carboxy-S-adenosyl-L-methionine synthase + Fungal lipase-like domain + RNA helicase HrpA + CRISPR-associated protein, Cmr3 + Divergent 4Fe-4S mono-cluster + Nitrate reductase, alpha subunit, N-terminal + RNA polymerase sigma-70 RpoE type + Addiction module antidote protein, HI1420 + Cellulose synthase operon protein BcsQ + Oxygen-dependent choline dehydrogenase + Neurotransmitter-gated ion-channel ligand-binding domain + Arc-like DNA binding domain + 6-phosphogluconate dehydratase + Domain of unknown function DUF2157 + Protein translocase SEC61 complex, gamma subunit + Domain of unknown function DUF3412 + Phage replisome organiser, N-terminal domain + Protein of unknown function DUF4153 + Malonyl-CoA decarboxylase, N-terminal + Tubulin-like + Protein O-mannosyl-transferase, C-terminal four TM domain + Ribosomal protein S3, eukaryotic/archaeal + Archaeal/bacterial translation initiation factor SUI1 + Thiamine transporter ThiT + Protein of unknown function DUF1282 + Cysteine synthase CysM + Protein of unknown function DUF3429 + Domain of unknown function DUF4296 + RNHCP domain + Putative zinc ribbon domain + Na+/H+ antiporter NhaC + Restriction endonuclease, type II, EcoRI/MunI + Replication initiation factor + Replication protein C + Protein of unknown function DUF4169 + Malate dehydrogenase, active site + Zeta toxin domain + Protein of unknown function DUF1572 + Protein of unknown function DUF2158 + Mechanosensitive ion channel inner membrane domain 1 + tRNA wybutosine-synthesizing protein + Glycosyl hydrolases related to GH101 family, GHL1-GHL3 + Aminotransferase, putative + Conserved hypothetical protein CHP03790 + Ricin B, lectin domain + Conjugal transfer, TrbG/VirB9/CagX + Phosphofructokinase, mixed-substrate PFK group III + Protein of unknown function DUF3617 + Diol/glycerol dehydratase, large subunit + D-aminoacyl-tRNA deacylase DtdA + Glycerophosphoryl diester phosphodiesterase, membrane domain + Beta propeller phytase + Flagellar regulatory FleQ + MiaB-like tRNA modifying enzyme, archaeal-type + DNA polymerase III, tau subunit, domain V + Acyl-CoA desaturase + Protein of unknown function DUF3341 + Protein of unknown function DUF3014 + Poly(A) polymerase I + Glycoside hydrolase family 27/36, conserved site + Putative bacilliredoxin, YphP/YqiW family + Domain of unknown function DUF4376 + Phage holin, LL-H family + Uncharacterised protein MJ0570, ATP-binding + Zinc finger, DPH-type + MucB/RseB, C-terminal + TTHA0068-like domain + Glycosyl hydrolases family 31, active site + Flagellar biosynthesis protein FlhF + Protein of unknown function DUF507 + Transposase, Synechocystis PCC 6803 + Ribosomal protein L23 + N-acetyl sugar amidotransferase + Ribonuclease Zc3h12a-like, NYN domain + Ubiquitin-conjugating enzyme E2 + Lipoprotein NlpA family + Topoisomerase I C-terminal domain + Transcriptional regulator, AbiEi 3 antitoxin, Type IV TA system + Methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase + Ribosomal protein S5/S7, eukaryotic/archaeal + Protein of unknown function DUF1826 + Porin, LamB type + Uncharacterised protein family, calcium binding protein, CcbP + DNA/RNA non-specific endonuclease, active site + Cobalt transporter subunit CbtA, putative + Dyp-type peroxidase + Hydroxymethylglutaryl-CoA reductase, N-terminal + L-aspartate dehydrogenase, archaeal + 4-hydroxy-2-oxovalerate aldolase + Conserved hypothetical protein CHP03214, putative allantoin-urate catabolism protein + Domain of unknown function DUF4478 + Protein of unknown function DUF268, Caenorhabditis species + PD-(D/E)XK nuclease superfamily 9 + Pilus biogenesis/stability type IV, PilW + Protein of unknown function DUF616 + L-2,4-diaminobutyric acid acetyltransferase + Protein of unknown function DUF1304 + Oleate hydratase + Restriction endonuclease, type II, AccI + Alkyl sulfatase, C-terminal + 1,2-phenylacetyl-CoA epoxidase, subunit A + 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type + Protein of unknown function DUF3098 + Protein of unknown function DUF3090 + DNA helicase, AddA type + Protein of unknown function DUF1460 + Orn/Lys/Arg decarboxylase, C-terminal + Phosphomannose isomerase, type I, conserved site + UPF0255 family + Potassium channel, voltage-dependent, beta subunit, KCNAB-related + Protein of unknown function DUF2480 + CRISPR-associated protein Cas5, HALMA + Putative aminohydrolase SsnA + NADH:ubiquinone oxidoreductase, subunit G + Type IV / VI secretion system, DotU + AbrB duplication + Protein of unknown function DUF3329 + Glutamate--cysteine ligase, plant-type + Nascent polypeptide-associated complex (NAC), archaeal + Restriction endonuclease, type II, XhoI + Putative PepSY TM-like protein + Impact family, bacterial/archaeal + Aspartate-semialdehyde dehydrogenase, gamma-type + Pathogenicity locus + Ribosomal protein L30, archaeal + Stealth protein CR2, conserved region 2 + Phosphonate metabolim protein, transferase hexapeptide repeat family + ISC system FeS cluster assembly, IscX + tRNA-guanine(15) transglycosylase + NMD3 + DNA polymerase family X + Cache 3/Cache 2 fusion domain + Protein of unknown function DUF790, endonuclease-like + Free Met sulfoxide reductase conserved site + Ribosomal protein S2, eukaryotic/archaeal + Peptidase M43, pregnancy-associated plasma-A + Thiazole biosynthesis domain + Protein of unknown function DUF2240 + Transposase, IS4, N-terminal + Aryldialkylphosphatase, zinc-binding site + Protein of unknown function DUF5372 + Translation initiation factor 2, beta subunit + Protein of unknown function DUF2847 + Glycogen debranching enzyme, GlgX type + Peptidoglycan hydrolase FlgJ + SLA1 homology domain 1, SHD1 + DNA-binding protein Fis + Protein of unknown function DUF1706 + Iron hydrogenase, subset + Xanthine dehydrogenase, small subunit + T1SS-143 repeat-containing domain + Methyltransferase, putative + Domain of unknown function DUF1724 + SEFIR domain + Translation initiation factor 1A (eIF-1A), conserved site + Ribosomal protein S27e + Transaldolase type 2 + 5-carboxymethyl-2-hydroxymuconate isomerase + FAD-binding 9, siderophore-interacting + Dam-replacing + Protein of unknown function DUF3830 + Ribose 1,5-bisphosphate phosphokinase PhnN + Putative N-acetylmannosamine-6-phosphate epimerase + Motility protein FimV, C-terminal + Conserved hypothetical protein CHP03643 + JAB1/MPN/MOV34 metalloenzyme domain + 5,6-dimethylbenzimidazole synthase BluB + Type II secretion system protein I domain + Glutaredoxin-like protein, YruB + Uncharacterised conserved protein UCP037409, membrane transporter, MTH672 + Protein of unknown function DUF4294 + PD-(D/E)XK nuclease superfamily 7 + Acyl-CoA dehydrogenase, C-terminal + Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic + Protein of unknown function DUF2937 + Putative amidoligase enzyme + Malate:quinone-oxidoreductase + Protein of unknown function DUF1963 + Bacteriophage 933W, L0084 + Metallophosphoesterase, DNA ligase-associated + Periplasmic sensor domain CHASE8 + Protein of unknown function DUF3305 + Oxaloacetate decarboxylase, alpha subunit + Acetoacetate decarboxylase + Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 + Protein of unknown function DUF4295 + Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain + Crotonyl-CoA reductase + Uncharacterised protein family CreA + Cu(I)-responsive transcriptional regulator + Uncharacterised protein family UPF0319 + Gene transfer agent, rcc01693 + Uncharacterised protein family UPF0348 + Putative ABC-transporter type IV CmpB/TMEM229 + DNA topoisomerase I, archeal-type + Structural protein of head Gp20 + Putative hydrolase RBBP9/YdeN + Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) + Nicotianamine synthase + Protein of unknown function DUF4058 + Carotene biosynthesis associated membrane protein + Exosome complex component Rrp41 + Ribosomal protein S27e, zinc-binding domain + Development/cell death domain + Peptidase M4 + Outer membrane protein Omp28 + Protein of unknown function DUF2970 + Arginine deiminase + Helicase domain + tRNA nucleotidyltransferase, archaea + Domain of unknown function DUF4426 + DNA polymerase II large subunit DP2 + Domain of unknown function DUF2383 + Nicotinate phosphoribosyltransferase + Knr4/Smi1-like domain + Oligosaccharyl transferase, archaeal + Chalcone isomerase + Protein of unknown function DUF3530 + Protein of unknown function DUF624 + Heme biosynthesis-associated TPR protein + Alternate ATP synthase, F1 complex, subunit epsilon + FERM/acyl-CoA-binding protein, 3-helical bundle + Protein of unknown function DUF1177 + Protein of unknown function DUF1326 + Translation elongation factor EF1A, eukaryotic/archaeal + PT repeat + Protein of unknown function DUF2788 + Putative L,D-transpeptidase catalytic domain + Pyruvate carboxylase + Delta-1-pyrroline-5-carboxylate dehydrogenase + Protoporphyrinogen oxidase + DNA-directed RNA polymerase, 14-18kDa subunit, conserved site + CRISPR-associated exonuclease Csa1 + Protein of unknown function DUF2177, membrane + Protein of unknown function DUF4251 + Putative bacterial antitoxin YdaS + Protein of unknown function DUF309 + Domain of unknown function DUF5118 + Type II secretion system protein I + Autoinducer synthesis, conserved site + DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type + Protein of unknown function DUF1043 + tRNA pseudouridine synthase B family + Glycoside hydrolase family 17 + Ribosomal protein S10, eukaryotic/archaeal + Histone H5 + Sulfite dehydrogenase SoxC + Lysine biosynthesis protein LysW + Ribosome modulation factor + CopC domain + TamA, POTRA domain 1 + Protein of unknown function DUF2953 + Squalene cyclase, N-terminal + Spt4/RpoE2 zinc finger + Protein of unknown function DUF2975 + Lysophospholipase patatin, conserved site + Glycogen/starch/alpha-glucan phosphorylase + Protein of unknown function DUF1376 + Succinylarginine dihydrolase + 4-hydroxybenzoate decarboxylase subunit C + Haem peroxidase, animal type + Alpha,alpha-trehalose-phosphate synthase + Peptidase M64, IgA + General secretion pathway protein F + Polypeptide-transport-associated, ShlB-type + KH-domain/beta-lactamase-domain protein, archaea + Glycosyl hydrolase family 53 + Alpha-macroglobulin, receptor-binding + Uric acid permease UacT-like + Restriction endonuclease, type II, Alw26I/Eco31I/Esp3I + YqcC-like domain + 5-keto-4-deoxyuronate isomerase, N-terminal domain + YP001051499.1-like domain + Signal transduction response regulator, nitrogen regulation NR(I) + PEP-CTERM locus, polysaccharide deactylase + Putative zincin peptidase + Energy-coupling factor transporter ATP-binding protein EcfA1 + Phosphonate C-P lyase system, transcriptional regulator PhnF + Type VI secretion system, lysozyme-related protein + Protein of unknown function DUF4321 + Proteasome alpha subunit, archaeal + Conserved hypothetical protein CHP00488 + Signal transduction histidine kinase + Conserved hypothetical protein CHP01210 + Protein of unknown function DUF4293 + D,D-heptose 1,7-bisphosphate phosphatase + Domain of unknown function DUF2087 + Protein of unknown function DUF2806 + Protein of unknown function DUF4194 + Sporulation regulator WhiA, C-terminal + Protein of unknown function DUF1349 + S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea + Domain of unknown function DUF4130 + C-type lectin-like + Acetyl-CoA decarbonylase/synthase complex subunit alpha + Thiamin/thiamin pyrophosphate ABC transporter, substrate-binding protein, Proteobacteria + DNA-directed RNA polymerase, subunit N/Rpb10 + Putative conjugal transfer protein TraF-related + Tetrahydromethanopterin S-methyltransferase, F subunit + Late competence development protein ComFB + Bacteriophage Mx8, p63, C-terminal + Protein of unknown function DUF4911 + Diphthamide synthesis Dph2, archaea + Amphi-Trp domain + Domain of unknown function DUF4367 + MCM N-terminal domain + AB hydrolase 4, conserved site + Zinc-ribbon 15 + Murein peptide ligase + 2-oxo-acid dehydrogenase E1 component homodimeric type + Bacilysin exporter BacE, putative + Uncharacterised conserved protein UCP033535, periplasmic lipoprotein + Enterobactin synthetase-like, component D + Flagellar assembly protein T, N-terminal + Glycosyl hydrolase family 36, N-terminal + Band 7, C-terminal extension + Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria + tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea + Protein of unknown function DUF1835 + MAM domain + Domain of unknown function DUF1595 + Sulphite reductase, dissimilatory-type alpha subunit + Potassium transporter + Ribosomal protein L32e, conserved site + Pyroglutamyl peptidase I, Cys active site + Hemin uptake protein HemP + Adenylate dimethylallyltransferase + Transcription elongation factor 1 + NADPH-dependent F420 reductase + Co-chaperone Hsc20 + Peroxiredoxin OsmC + ChaB + Inosine monophosphate cyclohydrolase-like + Protein of unknown function DUF3466 + DnaA regulatory inactivator Hda + Protein of unknown function DUF1512 + Signal transduction histidine kinase, phosphate regulon sensor PhoR + DNA-directed RNA polymerase subunit A'' + DNA-directed RNA polymerase subunit A' (Rpo1N) + Siderophore-interacting protein + Carotenoid/retinoid oxidoreductase + Protein of unknown function DUF2116, Zn-ribbon + Sjoegren syndrome/scleroderma autoantigen 1 + F420H(2)-dependent quinone reductase + Protein of unknown function DUF3788 + DNA polymerase alpha/epsilon, subunit B + RIO2 kinase winged helix domain, N-terminal + Sulphate ABC transporter permease protein 2 + tRNA pseudouridine synthase, Pus10 + Haem-binding domain, putative + Peptidase M20/DapE, YgeY + Respiratory nitrate reductase beta, C-terminal + Fatty acid desaturase, type 2 + Replication protein-C C-terminal + Archaeal Type IV pilin, N-terminal + Antirestriction + Protein of unknown function DUF1315 + RecBCD enzyme subunit RecC + Arsenate resistance ArsH + Nitrile hydratase, alpha subunit + Beta-ketoadipyl CoA thiolase + Sporulation regulator WhiA-like + Methyl-coenzyme M reductase, protein C-like + Conserved hypothetical protein CHP03684 + Domain of unknown function DUF1587 + Plasmid replication protein, RepL + Alkaline phosphatase, active site + Adenylyl cyclase class-4/guanylyl cyclase, conserved site + Porin, Gram-negative type + Chloramphenicol acetyltransferase + Domain of unknown function DUF2241 + Protease, Mu phage/prophage I type + Lysine-2,3-aminomutase + Methyl-coenzyme M reductase, alpha subunit, N-terminal + Domain of unknown function DUF1017 + Phosphoglucomutase, alpha-D-glucose specific + 4-aminobutyrate aminotransferase, bacterial + Mannitol repressor MtlR-like + Domain of unknown function DUF3662 + [LysW]-lysine/[LysW]-ornithine hydrolase + tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal + Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain + TerD domain + IPTL-CTERM protein sorting domain + B12-binding domain/radical SAM domain protein, Ta0216 family + Protein of unknown function DUF3549 + Gliding motility-associated protein GldE + Cytochrome c oxidase, subunit I bacterial type + Cellulose synthase BcsB, bacterial + XPG conserved site + Spore germination GerAB + Phosphonate ABC transporter, substrate-binding protein + Glutathione-disulphide reductase + O-acyltransferase WSD1, C-terminal + Restriction endonuclease, type II, Eco29kI + CRISPR-associated protein Cmr2, N-terminal + Ribosomal protein S9, archaeal + NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 + Protein of unknown function DUF4286 + Protein of unknown function DUF1284 + Pilus modification type IV, PilV + SRA-YDG + DNA replication terminus site-binding protein + Membrane-bound transcription factor site-2 protease + Chlorhexidine efflux transporter + Protein of unknown function DUF3124 + Protein of unknown function DUF1922 + 2-methyl-aconitate isomerase PrpF + 2-aminoethylphosphonate--pyruvate transaminase + ABC transporter, lipid A export, MsbA + Cell division protein ZipA + Protein of unknown function DUF3726 + YcxB-like protein + NIF system FeS cluster assembly, NifU + H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 + Protein of unknown function DUF2884 + Protein of unknown function DUF2789 + Methane/phenol/toluene hydroxylase + Retropepsins + Bacteriophage CI repressor + Peptidase M20A, peptidase V-related + Glucose dehydrogenase, C-terminal + Uncharacterised conserved protein UCP028770 + Translation initiation factor aIF-2, archaea + CRISPR-associated protein Cas7, subtype I-B/Tneap + Encapsulating protein for peroxidase + Glycoside hydrolase family 30 + Protocatechuate 3,4-dioxygenase, alpha subunit + Protein of unknown function DUF3015 + Type-2 restriction enzyme NgoMIV + Folate-biopterin transporter + Outer membrane protein assembly factor BamB + Signal transduction histidine kinase, PEP-CTERM system, putative + Tetrahydromethanopterin S-methyltransferase, subunit D + Type VI secretion system IcmF, C-terminal + Alcohol ABC transporter, permease protein + Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex + Glycoside hydrolase, family 35 + FUN14 + Ribonuclease T2, His active site 2 + Protein of unknown function DUF1887 + Lysine-2,3-aminomutase-like + Protein of unknown function DUF799 + Caudovirus, tape measure, N-terminal + DNA topoisomerase VI, subunit B + DNA topoisomerase III + Replication gene A protein + Diaminopropionate ammonia-lyase + GxGYxYP putative glycoside hydrolase, C-terminal + Protein of unknown function DUF1837 + Tetrahydromethanopterin S-methyltransferase, subunit C + Bacteriophage lambda, Bet + PqqC-like protein + Ribosomal protein L3, archaeal + MHYT domain + Cobalt transporter subunit CbtB, putative + Protein of unknown function DUF3472 + Gas vesicle protein GvpK + Amino-acid N-acetyltransferase + rRNA small subunit methyltransferase F, RNA-binding PUA-like domain + Protein of unknown function DUF2835 + Formate dehydrogenase-N, alpha subunit + CSLREA domain + 3-hydroxyanthranilic acid dioxygenase + Glutamyl-Q tRNA(Asp) synthetase + Protein of unknown function DUF1820 + Protein of unknown function DUF4406 + Intracellular proteinase inhibitor BsuPI + Sulphoacetaldehyde acetyltransferase + UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase + Restriction endonuclease, type II, XamI + 3-oxoadipate enol-lactonase 1/2 + VWFA-related, acidobacterial-type + Alpha carbonic anhydrase + Domain of unknown function DUF551 + C-type lysozyme inhibitor + Trehalose synthase/alpha-amylase, N-terminal + Periplasmic sensor domain + Protein of unknown function DUF2802 + L-fucose isomerase + Platelet-activating factor acetylhydrolase-like + Eukaryotic/archaeal PrmC-related + ELWxxDGT repeat + Type IV secretion system, VirB3 / TrbD / AvhB + Single-strand annealing protein SAK3 + Cadherin-like beta sandwich domain + Threonine dehydratase, catabolic + Protein of unknown function DUF2182, transmembrane, metal-binding + Mannitol dehydrogenase, conserved site + SprA-related family + DNA single-strand annealing protein RecT + Protein of unknown function DUF4112 + Domain of unknown function DUF4266 + Phosphoenolpyruvate carboxylase, Lys active site + Protein of unknown function DUF3187 + Protein of unknown function DUF4861 + Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A + Lipoprotein repeat + Phosphoribosylformylglycinamidine synthase + Ureide permease + Domain of unknown function DUF4114 + Gliding motility-associated lipoprotein, GldD + Molybdenum cofactor biosynthesis protein A, archaea + DEXH box helicase, DNA ligase-associated + Ubiquitin-associated domain + Iron-binding protein IscA, proteobacteria + Protein of unknown function DUF2909 + Conserved hypothetical protein CHP02444 + PQQ-dependent catabolism-associated beta-propeller protein + RNAse P, Rpr2/Rpp21 subunit + Ribosomal protein L24e-related + Myo-inositol-1-phosphate synthase + DNA binding HTH domain, Psq-type + Zinc finger, ZPR1-type + CofG family + Ribosomal protein L10e, conserved site + MEDS domain + CxxxxCH...CXXCH motif, Geobacter sulfurreducens + 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB + Peptidase M3B, oligoendopeptidase F + Glutamate--cysteine ligase, monofunctional + Domain of unknown function DUF4346 + Ribosomal protein S13, archaeal + RNA polymerase sigma factor RpoS + Flagellar assembly protein FliH + Domain of unknown function DUF202 + 4-[[4-(2-aminoethyl)phenoxy]-methyl]-2-furanmethanamine-glutamate synthase + ERAP1-like C-terminal domain + dTDP-4-amino-4,6-dideoxygalactose transaminase WecE-like + Protein of unknown function DUF4917 + SatD family + FAD-binding 8 + Nitrile hydratase accessory protein, putative + Domain of unknown function DUF2070, membrane + Thiamine biosynthesis protein ThiF + Arylamine N-acetyltransferase + CHASE3 + Protein of unknown function DUF883, ElaB + Syd + 2-methylisocitrate lyase + HTH DNA binding domain + ECF transporter S component, folate family + CRISPR-associated protein TM1795 + Glyceraldehyde-3-phosphate dehydrogenase, type II + Cleaved adhesin + Stealth protein CR1, conserved region 1 + Protein of unknown function DUF2815 + Mobile mystery protein B + Protein of unknown function DUF1569 + ProQ/FinO domain + Benzoate-CoA ligase family + Restriction endonuclease, type II, HaeII + Protein of unknown function DUF1659 + Translation elongation factor EFG/EF2, archaeal + CRISPR-associated RAMP Cmr4 + 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain + Head-to-tail joining protein W + Organic hydroperoxide resistance protein famiy + Protein of unknown function DUF227 + Uncharacterised protein family, MJ1172 + Nitrogenase cofactor biosynthesis protein NifB + Inner membrane component domain + Alanine-tRNA ligase, archaea + Translation initiation factor 2, gamma subunit + Protein of unknown function DUF3306 + C1q domain + Protein of unknown function DUF1403 + 7,8-dihydro-8-oxoguanine triphosphatase + Translation elongation factor EF1B, beta chain, archaeal + Protein of unknown function DUF3192 + PTP type protein phosphatase + N-acetylneuraminate synthase + CO dehydrogenase/acetyl-CoA synthase delta subunit + Lon protease, archaeal + Polysaccharide lyase 8, N-terminal alpha-helical + Protein of unknown function DUF1186 + Oligogalacturonate lyase domain + Strictosidine synthase, conserved region + Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein + Sublancin immunity protein SunI + Protein of unknown function DUF2780, VcgC/VcgE + Protein of unknown function DUF3360 + Inactive transglutaminase fused to 7 transmembrane helices + Bacterial virulence protein VirB8 + Translation elongation factor, IF5A C-terminal + Histidinol-phosphate phosphatase, putative, inositol monophosphatase + Protein of unknown function DUF3373 + Molybdenum cofactor carrier, putative + TRL-like protein family + Cobaltochelatase subunit CobS + Aspartyl/asparaginy/proline hydroxylase + Adenylylsulphate reductase, beta subunit, C-terminal + CRISPR-associated protein, Cmr5 + tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal + Vitamin K epoxide reductase + TraG-like, N-terminal + GPI mannosyltransferase 2 + S-ribosylhomocysteinase (LuxS) + Bacterial transcriptional repressor TetR + Uncharacterised domain UPF0547 + Microcin J25-processing protein McjB, C-terminal + DNA-directed RNA polymerase subunit B (Rpo2) + Ectoine biosynthetic protein + Choline-sulfatase + NifC-like ABC-type porter + Ferric iron reductase FhuF domain + Sulphite reductase, dissimilatory-type beta subunit + Ribosomal protein L14P, archaeal + Ribosomal protein L4 + YoaP-like domain + Protein of unknown function DUF1425 + Acyl-CoA-binding protein, ACBP + 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal + Hom-end-associated Hint + Domain of unknown function DUF3880 + Protein of unknown function DUF817 + 4-hydroxybenzoate 3-monooxygenase + 5-deoxy-glucuronate isomerase, IolB + RNA polymerases, subunit N, zinc binding site + Protein of unknown function DUF2812 + 3-hexulose-6-phosphate isomerase + Glycoside hydrolase, family 32, active site + Activator of aromatic catabolism + Lysine exporter LysO + Domain of unknown function (DUF4878) + Glutathionylspermidine synthase, pre-ATP-grasp-like domain + Protein of unknown function DUF3300 + Protein of unknown function DUF2848 + Muconolactone isomerase domain + Alternate ATP synthase, F0 complex, subunit C, bacterial/archaeal + Zn-ribbon containing protein + Haemolysin-type calcium binding-related + Phenylacetic acid degradation protein PaaN + Hut operon regulatory protein HutP + 26S proteasome regulatory subunit P45-like + Ribonuclease T + B12-dependent dehydratases, beta subunit + Nitrate reductase, beta subunit + Superoxide dismutase, copper/zinc, binding site + tRNA U34 carboxymethyltransferase + Threonine dehydratase, biosynthetic + DNA-binding pseudobarrel domain + T5SS/PEP-CTERM-associated repeat + Phage virion morphogensis protein + Glycerol-3-phosphate responsive antiterminator + Carboxylesterase type B, conserved site + Adenylate cyclase, class-I + Protein of unknown function DUF480 + YnbE-like lipoprotein + Domain of unknown function DUF2786 + Inner membrane protein YejM, N-terminal + 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase + Protein of unknown function DUF669 + Flagellar + Protein of unknown function DUF664 + Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic + Carbohydrate-binding domain-containing protein Cthe_2159 + Conserved hypothetical protein CHP02443 + 8-oxoguanine DNA glycosylase, N-terminal + Ribosomal protein L21e, conserved site + Nitrous-oxide reductase, Sec-dependent + TerB, N-terminal + Predicted virulence protein, SciE type + Helicase HerA, barrel domain + Domain of unknown function DUF2314 + TipAS antibiotic-recognition domain + Protein of unknown function DUF1852 + tRNA (cytidine/uridine-2'-O-)-methyltransferase + Uncharacterised conserved protein UCP004962 + Murein transglycosylase-C, N-terminal + Protein of unknown function DUF2997 + Domain of unknown function DUF1570 + Restriction endonuclease, type II, Pab1 + Type-2 restriction enzyme NaeI + tRNA(Met) cytidine acetyltransferase TmcA, N-terminal + TrwC relaxase + DM13 domain + Protein of unknown function DUF3102 + Protein of unknown function DUF5362 + Type-IV secretion system protein TraC/Conjugative transfer ATPase + Domain of unknown function DUF2220 + Nitrile hydratase, beta subunit + DNA repair and recombination protein RadB + Myxococcus cysteine-rich repeat + Iron permease FTR1/Fip1/EfeU + Domain of unknown function DUF3631 + MoCo/4Fe-4S cofactor protein extended Tat translocation domain + Type VI secretion system, IcmF + Pili assembly chaperone, N-terminal + Flavocytochrome c + Homeodomain, phBC6A51-type + Bulb-type lectin domain + Diol/glycerol dehydratase/dehydratase reactivating factor + Protein of unknown function DUF3080 + Regulator of nucleoside diphosphate kinase, N-terminal domain + Metallophosphoesterase, TT1561-like + Protein of unknown function DUF2082, nucleic-acid-binding, Zn-ribbon + Mor transcription activator + Conserved hypothetical protein CHP02284 + Conserved hypothetical protein CHP02293 + Phage Tail Protein X-like + Insecticide toxin TcdB middle/N-terminal + Oxidoreductase putative, C-terminal + Cobaltochelatase, CobN subunit + DNA binding protein Tfx, C-terminal + Transmembrane Gly-Cys-Arg, conserved site + RNA 3'-terminal phosphate cyclase-like, conserved site + Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site + Peptidase S37, tripeptidyl aminopeptidase + Archaeoflavoprotein AfpA + Phosphotransferase system, sugar-specific permease EIIA type 1 + Bacterial glucose/galactose transporter + Min27-like integrase, DNA-binding domain + Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain + Type IV conjugative transfer system protein TraH + Domain of unknown function DUF190 + DNA modification/repair radical SAM protein, putative + Alcohol dehydrogenase, zinc-binding type 1 + Copper resistance B precursor + GxGYxYP putative glycoside hydrolase, N-terminal + RecBCD enzyme subunit RecB + Dicarboxylate transport + Signal transduction response regulator, PEP-CTERM system, putative + Uncharacterised protein family NKWYS + Glutamate mutase epsilon subunit + SP1917 domain + Protein of unknown function DUF2986 + Ethanolamine ammonia-lyase light chain + Uncharacterised conserved protein UCP004977 + UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase + Glycosyl hydrolase family 36, C-terminal + Radical SAM/Cys-rich domain protein + Fructose-1,6-bisphosphate aldolase, class 2 + Domain of unknown function DUF4435 + Protein of unknown function DUF131 + Outer membrane protein SusF/SusE + Uncharacterised conserved protein UCP028291 + DNA metabolism protein, putative + Conserved hypothetical protein CHP00062 + Domain of unknown function DUF2293 + Protein of unknown function DUF2628 + Mechanosensitive ion channel MscS, porin domain + Purine catabolism PurC-like domain + Tetrahydromethanopterin S-methyltransferase, subunit G + Ammonia monooxygenase/particulate methane monooxygenase, subunit B + Protein of unknown function DUF4834 + Alcohol dehydrogenase GroES-associated + Protein of unknown function DUF4625 + Tetrahydromethanopterin S-methyltransferase subunit B + Protein of unknown function DUF2834 + Protein of unknown function DUF4421 + Glycoside hydrolase, family 8 + Coenzyme PQQ biosynthesis protein E, bacteria + Coenzyme PQQ biosynthesis protein B + Bacteriophage A118, Gp4, minor capsid + Protein of unknown function DUF1905 + Kazal domain + Protein of unknown function DUF416 + Nitrate reductase, alpha subunit + tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA + Poly(R)-hydroxyalkanoic acid synthase, class III, PhaE subunit + Magnesium-chelatase, subunit H + Spermine/spermidine acetyltransferase, N-terminal domain + Glycine/sarcosine/betaine reductase complex, protein B, subunit alpha/ beta + Acyl-CoA dehydrogenase, C-terminal domain + Dihydroxyacetone kinase DhaK, subunit 1 + Conserved hypothetical protein CHP02647 + Protein of unknown function DUF4920 + O-acyltransferase, WSD1, N-terminal + ISC system FeS cluster assembly, IscU scaffold + Profilin conserved site + Peptidase aspartic, AF0612 + Protein of unknown function DUF1495 + HTH-type transcriptional repressor, C-terminal + Bacteriophage Mu, Gp36 + DNA repair protein Rad52/59/22 + Polysaccharide lyase family 8, central domain + CRISPR-associated protein Csc2 + Lipopolysaccharide heptosyltransferase I + Cell division protein ZapD + Thiosulphate/Sulfate-binding protein + CRISPR-associated protein Csh1, C-terminal + Ergothioneine biosynthesis protein EgtB + Putative methanogenesis marker protein 14 + 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal + Restriction endonuclease, type II, SacI + Exosortase D, VPLPA-CTERM-specific + Steroid delta5-4-isomerase + Ferredoxin 2Fe-2S type, proteobacteria + Tetrahydromethanopterin S-methyltransferase, subunit E + Protein of unknown function DUF2164 + Bacteriophage T7, Gp4, DNA primase/helicase, N-terminal + Nitrogenase iron protein NifH + CRISPR-assoc protein, NE0113/Csx13 + Protein of unknown function DUF2955 + Exosortase-related protein XrtF + Glycoside hydrolase, family 76 + Outer membrane insertion C-terminal signal, omp85 target + Calcineurin-like phosphoesterase, C-terminal + D,L-carboxypeptidase, peptidase domain + DNA sulphur modification protein DndD + Fibrogen-binding domain 1 + S-adenosylmethionine decarboxylase, bacterial + Gliding motility-associated lipoprotein, GldB + Gliding motility-associated protein, GldC + CRISPR-associated protein Cas1, NMENI subtype + Lsm, C-terminal + Protein of unknown function DUF4491 + Quinoprotein dehydrogenase-associated SoxYZ-like carrier + Nitrogenase MoFe maturation protein, NifZ + Putative citrate transporter + Thiopurine S-methyltransferase, Se/Te detoxification + Protein of unknown function DUF3347 + Domain of unknown function DUF1829 + Cobalt transport protein ATP-binding subunit + Energy coupling factor transporter S component ThiW + Outer membrane porin, bacterial + Putative exopolysaccharide exporter + Aminotransferase, LLPSF_NHT_00031 family + Porin, alpha proteobacteria type + Isopropylmalate/citramalate/homocitrate synthase + Glycoside hydrolase, family 37, conserved site + DNA topoisomerase I, N-terminal + Gliding motility-associated lipoprotein GldJ + Protein of unknown function DUF3731 + Gliding-associated putative ABC transporter substrate-binding GldG + Ribosomal protein L39e domain + Uncharacterised protein family UPF0179 + Transcription activator HlyU + Domain of unknown function DUF4395 + Glycogen debranching enzyme, archaeal type + Protein of unknown function DUF5062 + Sodium/proline symporter + Uncharacterised protein family UPF0058 + Ribosome biogenesis factor NIP7-like + Entericidin A/B + LETM1-like + EH signature domain + ABC-2 membrane transporter-like + YukD-like + Protein of unknown function DUF1439 + Transaldolase type 1 + Four helix bundle suffix domain + Bacteriophage Mu, transposase + Reversibly glycosylated polypeptide family + Cytochrome c prime, subgroup + Toxin CcdB + Domain of unknown function DUF1971 + Phage shock protein B + YrhK domain + Lactoylglutathione lyase + Phosphonate C-P lyase system, PhnL + Type VI secretion system, FHA domain-containing protein + Type VI secretion system, lipoprotein SciN + Glycoside hydrolase family 26 + Putative phage-type endonuclease + Plasmid partitioning protein, RepA + Plasmid partitioning protein, RepB + Uncharacterised conserved protein UCP033199 + YMGG-like Gly-zipper + Domain of unknown function DUF4942 + Transcription initiation factor Rrn7, Zinc-finger + Lipase EstA/Esterase EstB + Protein of unknown function DUF4912 + Sporadically distributed protein CHP04141 + Daunorubicin resistance ABC transporter membrane protein + TraU + Methyl-coenzyme M reductase, alpha subunit, N-terminal subdomain 1 + CRISPR-associated protein Csd2 + Cystathionine beta-lyase, bacterial + Flavin monooxygenase FMO + Protein of unknown function DUF4845 + Pyroglutamyl peptidase I, bacterial-type + Lipoyltransferase/lipoate-protein ligase + Putative Na+/H+ antiporter, N-terminal + Protein of unknown function DUF2184 + Protein of unknown function DUF1362 + Protein of unknown function DUF3301 + Bacterioopsin activator-type, HTH domain + Phage/plasmid-like protein + Prokaryotic lipoprotein-attachment site + ADP/ATP carrier protein + Domain of unknown function DUF3859 + Pyridine nucleotide-disulphide oxidoreductase family protein, N-terminal + Gliding motility-associated lipoprotein GldK + Gliding motility-associated, peptidyl-prolyl isomerase, GldI + DEAD/DEAH-box helicase, putative, actinobacteria + Domain of unknown function DUF4236 + Virulence effector, SrfC + Ethanolamine utilisation EutA + Alpha-L-glutamate ligase-related protein + Glycoside hydrolase, family 19, catalytic + Protein of unknown function DUF3367 + Type VIII secretion system, CsgF + Protein of unknown function DUF2922 + Adenylylsulphate reductase, beta subunit + Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal + Shikimate kinase, archaea + Glycosyl transferase, family 17 + GPI mannosyltransferase + Adenosine 5'-phosphosulphate reductase + Gas vesicle protein GvpG + Ribosomal protein L10e + Protein of unknown function DUF3419 + L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase + Gelsolin-like domain + Aconitase B + Protein of unknown function DUF2269, transmembrane + PGF-pre-PGF domain + KfrA, N-terminal DNA-binding domain + Ribosomal protein S11, archaeal + Protein of unknown function DUF475 + Restriction endonuclease, type II, ApaLI + ABC transporter, choline, permease protein + Acetophenone carboxylase beta subunit/Acetone carboxylase gamma subunit + Phasin, subfamily 1 + CofH family + DnaJ-related protein, N-terminal + Ferredoxin-type protein, NapH/MauN family + Peptidase M10A + Protein of unknown function DUF3095 + Conserved hypothetical protein CHP03546 + Domain of unknown function DUF22 + Chaperone NapD, nitrate reductase assembly + Mga helix-turn-helix domain + Prophage tail endopeptidase + Methyl-coenzyme M reductase, gamma subunit + Protein patched/dispatched + Lipoprotein releasing system, ATP-binding protein + Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase + Serine hydrolase FSH + Protein of unknown function DUF3892 + Acyltransferase ChoActase/COT/CPT + Cysteine desulfurase IscS + L-fucose permease FucP + SWEET sugar transporter + High potential iron-sulphur protein + Chlorophyllase + Ammonia/methane monooxygenase, subunitB, N-terminal + 7-carboxy-7-deazaguanine synthase, Cx14CxxC-type + Peptidase M38, beta-aspartyl dipeptidase + S-adenosyl-L-methionine-dependent methyltransferase, putative + PQQ-dependent dehydrogenase, methanol/ethanol family + Protein of unknown function DUF1272 + Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase + (+) RNA virus helicase core domain + Protein of unknown function DUF3843 + CRISPR-associated protein Cmr2 + Uncharacterised protein family UPF0114, bacteria + SWIB/MDM2 domain + Type VI secretion system-associated, BMAA0400 + Protein of unknown function DUF3581 + Heme b synthase + LURP1-related protein domain + Bacteroidetes-Associated Carbohydrate-binding Often N-terminal + Pseudouridine synthase, RluA-like + Dihaem cytochrome c + Protein of unknown function DUF3185 + Putative peptidoglycan binding + Beta-galactosidase jelly roll domain + Deoxyribonuclease I + Uncharacterised conserved protein UCP006557 + Outer membrane protein OmpA-like, transmembrane domain + Protein of unknown function DUF2474 + Cyd operon protein YbgT + Coenzyme PQQ biosynthesis protein A + Succinyldiaminopimelate transaminase, DapC, beta/gammaproteobacteria + Domain of unknown function DUF4468 with TBP-like fold + Immunity protein 49 + Pseudaminic acid cytidylyltransferase + CRISPR-associated endonuclease Cas9 + Riboflavin synthase, archaeal + Putative sensor domain + O-GlcNAc transferase, C-terminal + Protein of unknown function DUF365 + Protein of unknown function DUF945 + 7,8-dihydroneopterin aldolase, MptD + Alpha-ribazole phosphatase, CobC + Ribosomal protein L38e + Predicted aminopeptidase + Uncharacterised conserved protein UCP028704, OpgC + Penicillin-binding protein 1B + Protein of unknown function DUF4043 + N-glycosylase/DNA lyase-like + Circularly permuted ATPgrasp domain + RNA methyltransferase, SpoU/TrmH type, C-terminal + Alkylhydroperoxidase/carboxymuconolactone decarboxylase family + Protein of unknown function DUF916, cell surface putative + Flagellar export ATPase FliI, clade 1 + Uncharacterised conserved protein UCP01500 + Protein of unknown function DUF460 + Rhodanase, C-terminal + Cytochrome P460 + NifT/FixU + Alkyl hydroperoxide reductase subunit F + Rhomboid-like serine protease, proteobacteria + Chemotaxis methyl-accepting receptor Tar-related, ligand-binding + Globin, bacterial-like, conserved site + Restriction endonuclease, type II, LlaJI + Uncharacterised protein family, YajG + Uncharacterised conserved protein UCP037266 + Alanine dehydrogenase, Archaeoglobus-type + Restriction endonuclease, type II, HindIII + Putative glycogen debranching enzyme, N-terminal + Protein of unknown function DUF4393 + Z ring-associated protein D, C-terminal domain + Lysine biosynthesis enzyme LysX + Nitrate transporter + Verrucomicrobia /Planctomycetes-restricted protein + Protein of unknown function DUF1290 + Protein of unknown function DUF2321 + Protein of unknown function DUF3106 + Putative methanogenesis marker protein 15 + Domain of unknown function DUF1610 + Gliding motility-associated protein GldM + Restriction endonuclease, type II, HpaII + Protein of unknown function DUF2764 + SGNH hydrolase-type esterase, N-terminal + Protein of unknown function DUF3754 + Piwi domain + Protein of unknown function DUF2193 + PEP-CTERM locus polysaccharide chain length determinant + Putative helix-turn-helix protein, YlxM/p13-like + Protein of unknown function DUF3841 + NifT/FixU barrel-like domain + DNA topoisomerase I catalytic fragment, domain 2 + DOMON domain + Xylose isomerase, bacterial-type + Menaquinone biosynthesis protein MenD, middle domain + Sporulation transcription regulator WhiA, N-terminal domain + O-antigen polysaccharide polymerase Wzy + Conserved hypothetical protein CHP04013, B12-binding/radical SAM-type + Metal-independent alpha-mannosidase + START domain + GvpD gas vesicle + Domain of unknown function DUF4080 + CopG-like ribbon-helix-helix domain + Ionotropic glutamate receptor + DNA primase, small subunit, eukaryotic/archaeal + [NiFe]-hydrogenase assembly, chaperone, HybE + Type II secretion system protein N, Leptospira-type + Baseplate hub assembly protein, bacteriophage T4-like + ATPase, type I secretion system + AHH domain-containing protein + Prokaryotic E2 family D + Macrophage infectivity potentiator + Domain of unknown function DUF4373 + Ribosomal protein L39e + DoxX-like family + Selenium-binding protein + Acyl-CoA thioesterase II domain + Isochorismate synthase + Proliferating cell nuclear antigen, PCNA, conserved site + Domain of unknown function DUF4444 + Domain of unknown function DUF4150 + Acetyl-coenzyme A transporter 1 + Domain of unknown function DUF2134, membrane + HAD-superfamily phosphatase, YqeG-like + Peptidase M64, N-terminal + LRAT-like domain + DNA-directed RNA polymerase, 30-40kDa subunit, conserved site + HTH-type transcriptional regulator ArgP + Cellulose synthase, subunit A + Aromatic amino acid hydroxylase, iron/copper binding site + Protein of unknown function DUF314 + Transcriptional regulator SgrR, N-terminal HTH domain + Membrane bound YbgT-like + Photosynthetic reaction centre, L/M + Putative RNA methyltransferase + Protein of unknown function DUF1810 + Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex + ATP-dependent DNA helicase Rep + Homoserine kinase, type II + Domain of unknown function DUF4166 + Uncharacterised conserved protein UCP018781, methanogenesis + Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site + ADP ribosyltransferase + Conserved hypothetical protein CHP02206, TP0381 + Type II secretion system, protein N + Gliding motility-associated ABC transporter ATP-binding subunit GldA + Phospholipase D/Transphosphatidylase + Putative monooxygenase YdhR + TyrR family, helix-turn-helix domain + Protein of unknown function DUF3780 + Lytic transglycosylase MltB + Putative oxidoreductase, C-terminal + Methyl-coenzyme M reductase, beta subunit, C-terminal + Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain + Uncharacterised conserved protein UCP019464, methanogenesis + Bacteriophage holin family + Methyl-coenzyme M reductase, protein C + Protein of unknown function DUF3379 + Ubiquitin domain + CRISPR-associated protein, CXXC-CXXC + Nitrate reductase cytochrome c-type subunit NapB + Conserved hypothetical protein CHP02449 + Protein of unknown function DUF2288 + DnaQ exonuclease/DinG helicase, predicted + Atu1913-like + ABATE domain + Protein of unknown function DUF4846 + Phosphatidylinositol 3-/4-kinase, catalytic domain + Domain of unknown function DUF4986 + Protein of unknown function DUF4465 + Trans-aconitate 2-methyltransferase, C-terminal + Glucose-fructose oxidoreductase, bacterial + Glycyl radical enzyme, HI0521, predicted + Protein of unknown function DUF2252 + 2OG-Fe dioxygenase + L-threonine 3-dehydrogenase + Domain of unknown function DUF2268 + Transcription factor 25 + Serine dehydratase, alpha subunit + DNA-binding protein Tfx, archaea + Ubiquinol-cytochrome c chaperone/UPF0174 + Nitrogenase component 1, alpha chain + Ribosomal protein L6, conserved site-2 + Type VI secretion system-associated, VCA0118 + Berberine/berberine-like + Beta-lactamase, class-A + Protein of unknown function DUF4402 + Quinoprotein dehydrogenase, conserved site + Choline ABC transporter, substrate-binding protein + Undecaprenyl-phosphate galactose phosphotransferase, WbaP + Protein of unknown function DUF3297 + Methyl coenzyme M reductase system, component A2 + Domain of unknown function DUF2183 + Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain + tRNAHis guanylyltransferase catalytic domain + Exosortase F-associated protein + Vps4 oligomerisation, C-terminal + Conserved hypothetical protein CHP04096 + Recombination-promoting nuclease RpnA + Type II secretion system protein B + Flagellar assembly protein T, middle domain + Urea transporter + CASTOR/POLLUX/SYM8 ion channels + Restriction endonuclease, type II, TaqI + Formate dehydrogenase, delta subunit + Protein of unknown function DUF1465 + 5-nucleotidase lipoprotein e(P4) + Chitin binding domain + Protein of unkown function DUF2303 + Flagellar hook-length control protein FliK + Homoprotocatechuate degradation transcriptional regulator HpaR + Fe/S biogenesis protein NfuA + Transcription factor HTH, IscR + PBP-dependent ABC transporters TM subunit, N-terminal + Methyl-coenzyme M reductase, beta subunit, N-terminal + von Hippel-Lindau disease tumour suppressor, beta domain + Modulator of Rho-dependent transcription termination + Sporulation stage 0, protein M + Glycogen synthase + Coiled stalk of trimeric autotransporter adhesin + Winged helix-turn-helix domain (DUF2582) + Protein of unknown function DUF4287 + ATP binding protein MinD, archaea + Protein of unknown function DUF501 + Protein of unknown function DUF4326) + Nucleotide-diphospho-sugar transferase + Putative methionine gamma-lyase + Frataxin/CyaY + Protein of unknown function DUF2865 + Domain of unknown function DUF3291 + Ribosomal protein L35A + Protocatechuate 3,4-dioxygenase beta subunit, N-terminal + Type VI secretion system-associated, ImpA + ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD + Protein of unknown function DUF2165, transmembrane + Exopolyphosphatase + 12,18-Didecarboxysiroheme deacetylase + DNA-directed RNA polymerase M, 15kDa subunit, conserved site + Ribosomal protein L31e, conserved site + Spondin, N-terminal + YaaC-like protein + Membrane-associated sensor domain MASE3 + Tetracycline regulation of excision, RteC + Protein of unknown function DUF4864 + Domain of unknown function DUF2172 + TonB-dependent haem/haemoglobin receptor + Glycoside hydrolase, family 62, arabinosidase + Cyclic dehypoxanthine futalosine synthase + C-terminal of Roc (COR) domain + Glucokinase ROK + Domain of unknown function DUF3502 + Uncharacterised protein family Smp + Sulphur transferase DndC, putative + Allantoinase + Opacity-associated protein A, N-terminal + Carbonic anhydrase, alpha-class, conserved site + Protein of unknown function DUF4437 + Molybdate transporter 1/2 + Chitobiase/beta-hexosaminidases, N-terminal domain + ABC transporter, substrate-binding protein, PQQ-dependent alcohol dehydrogenase system + YfbU, alpha-helical bundle domain + Oxidoreductase alpha (molybdopterin) subunit + Ribosomal protein S19e, conserved site + Peptidase S15, X-Pro dipeptidyl-peptidase + Protein of unknown function DUF2497 + Dihydroneopterin aldolase MtpD, C-terminal domain + Beta-lactamase, class-C active site + Toxin SymE-like + CRISPR-associated helicase, CYANO-type + Cytochrome b562 + Protein of unknown function DUF2947 + Protein of unknown function YvrJ + Tryptophan/tyrosine transporter + Transferrin receptor-like, dimerisation domain + Type II secretion system protein L + Domain of unknown function DUF4423 + Fimbrial isopeptide formation D2 domain + o-Succinylbenzoate synthase, MenC type 2 + Uncharacterised conserved protein UCP006577 + Domain of unknown function DUF1854 + Sulfopyruvate decarboxylase, beta subunit + Sugar transferase, PEP-CTERM system associated + Poly-gamma-glutamate hydrolase + Protein of unknown function DUF3081 + Protein of unknown function DUF3087 + Arginine N-succinyltransferase + Methyl-coenzyme M reductase, alpha subunit, C-terminal + Protein of unknown function DUF1700 + Dissimilatory sulphite reductase D + Chlamydiae/Verrucomicrobia/Planctomycetes small basic protein + Negative modulator of initiation of replication SeqA, N-terminal + Tail tubular protein Gp11 + Domain of unknown function DUF2828 + Phage shock protein, PspC + Carbohydrate-binding module family 5/12 + YheA/YmcA-like domain + Phosphonoacetate hydrolase, insert domain + Phosphotransferase system, IIA-like nitrogen-regulatory protein PtsN + GPI transamidase subunit PIG-U + Prokaryotic E2 family B + Protein of unknown function DUF2585 + Domain of unknown function DUF2760 + CRISPR-associated protein Csy2 + CRISPR-associated endoribonuclease Cas6/Csy4, subtype I-F/YPEST + Phosphonate metabolism PhnM + Non-homologous end joining protein Ku, prokaryotic type + Homocitrate synthase NifV-type + Polysaccharide lyase family 8, C-terminal + Conserved hypothetical protein CHP03032 + Fatty acid response transcription factor FadR + Domain of unknown function DUF4815 + Meso-diaminopimelate D-dehydrogenase, C-terminal + Helicase, SWF/SNF/SWI type, bacterial + Lipopolysaccharide-modifying protein + Golgi phosphoprotein 3-like + ISC system FeS cluster assembly, HscA chaperone + Sedoheptulose-1,7-bisphosphatase + Protein of unknown function DUF2809 + Gliding motility-associated ABC transporter permease protein GldF + COX aromatic rich motif + Protein of unknown function DUF3796 + Putative polyhydroxyalkanoic acid system protein + Cysteine desulfurase-related, unknown function + Propanediol/glycerol dehydratase, small subunit + Cytochrome c oxidase caa3-type, assembly factor CtaG-related + Monooxygenase component MmoB/DmpM + Pilus assembly TraE + Bacteriophage regulatory protein, Rha family + Nitrogen fixation protein NifW + Tocopherol cyclase + Beta-lactamase, class-D active site + Malate dehydrogenase, type 2 + LOR/SDH bifunctional enzyme, conserved domain + Rhamnogalacturonan lyase, domain III + Domain of unknown function DUF1727 + Phenylalanine-4-hydroxylase, monomeric form + Bacteriophage A500, Gp15 + L-lactate dehydrogenase, active site + Protocatechuate 3,4-dioxygenase, beta subunit + Zinc finger, C4 DksA/TraR-type + Type II pantothenate kinase + Protein of unknown function DUF4331 + Potassium channel, voltage-dependent, EAG/ELK/ERG + Chalcone/stilbene synthase, N-terminal + Cysteine-rich Golgi apparatus protein 1 repeat + Putative methanogenesis marker protein 1 + Conserved hypothetical protein CHP01626, YtfJ + Protein of unknown function DUF2513 + Conserved hypothetical protein CHP1671 + Protein of unknown function DUF3019 + CoB--CoM heterodisulphide reductase, subunit C + Bacteriophage lambda, Nu1, terminase small subunit + CRISPR-associated protein, TM1791 + Domain of unknown function DUF5001 + HupH hydrogenase expression protein, C-terminal + Cryptochrome DASH + Arginase + Methylaspartate ammonia-lyase + Protein of unknown function DUF4867 + Putative beta-lactamase-inhibitor-like, PepSY-like + Oxidoreductase-like, N-terminal + Protein of unknown function DUF3261 + 5,10-methylenetetrahydromethanopterin reductase + Glutaredoxin 2, C-terminal + Pyrrolysine biosynthesis protein PylD + Protein beta + Cytochrome c-550 PedF + Antitoxin of toxin-antitoxin, RelE / RelB, TA system + Beta-lactamase, class-A active site + Probable Zinc-ribbon domain + Outer membrane beta-barrel protein, Proteobacteria + Adenylate cyclase class-I, N-terminal domain + Holliday junction resolvase RecU + GDYXXLXY protein + Major outer membrane lipoprotein Oprl + Pyrrolysine biosynthesis protein PylC + Formate-dependent phosphoribosylglycinamide formyltransferase + Protein of unknown function DUF2938 + Histidine N-alpha-methyltransferase + S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type + 2-polyprenyl-6-methoxyphenol 4-hydroxylase + Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted + Sugar transferase, PEP-CTERM, Stp1 + Archaeosortase A + DNA-packaging protein gp3 + Peptidase S54, GlpG peptidase, N-terminal + Domain of unknown function DUF2470 + Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S + Prokaryotic Ubiquitin + Ribosomal protein S26e + Ribosomal protein S4e, N-terminal, conserved site + Barstar (barnase inhibitor) + Succinylglutamate-semialdehyde dehydrogenase + RNA polymerase, subunit H/Rpb5, conserved site + DOPA-like domain + PEF-CTERM protein sorting domain + Uncharacterised conserved protein UCP019322 + Phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein + CDKN3 domain + Ribosomal protein L30e, conserved site + Sulfopyruvate decarboxylase, alpha subunit + Homing endonuclease PI-Sce + Histone-like protein H-NS family, oligomerisation domain + Phosphoribosylaminoimidazole-succinocarboxamide synthase, Vibrio-type + Uncharacterised protein family UPF0304, YfbU + Protein of unknown function DUF2273 + Gas vesicle protein GvpN + Tir chaperone protein (CesT) family + Host-nuclease inhibitor protein Gam + Hexameric tyrosine-coordinated heme protein (HTHP) + Alkyl hydroperoxide reductase subunit C + Ammonia monooxygenase/particulate methane monooxygenase, subunit A + Protein of unknown function DUF975 + Type II secretion system protein C + L-rhamnose mutarotase + Type VI secretion system, ATPase ClpV1 + Histidine utilization repressor + Putative rRNA methylase + Uncharacterised protein family Rv2561 + DNA ligase D, polymerase domain + CRISPR-associated protein Csc1 + Citrate lyase acyl carrier protein CitD + Uncharacterised protein family UPF0060 + DNA helicase + Uncharacterised conserved protein UCP033924 + Conserved hypothetical protein CHP02594 + Domain of unknown function DUF4957 + Phosphoenolpyruvate phosphomutase, core + Phycobilisome, alpha/beta subunit + Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal + Dopa 4,5-dioxygenase + Pimeloyl-[acyl-carrier protein] methyl ester esterase + Protein of unknown function DUF3050 + Protein of unknown function DUF3526 + Chalcone/stilbene synthase, C-terminal + Ribosomal protein Rsm22-like + Uncharacterised protein family UPF0489 + Protein of unknown function DUF3016 + Spore coat protein U + Protein of unknown function DUF326 + Protein of unknown function DUF1961 + Curli assembly protein CsgE + HAD-superfamily phosphatase, subfamily IIIC + UDP-galactopyranose mutase + Cell division suppressor protein, SulA + Uncharacterised protein family PGPGW, transmembrane + Secretin, N-terminal + Protein of unknown function DUF2813 + Protein of unknown function DUF3575 + FAD-binding, type 1 + Capsid assembly scaffolding protein + Molybdenum cofactor cytidylyltransferase + Alternate ATP synthase, F0complex, subunit A + Protein of unknown function DUF2782 + CDP-alcohol phosphatidyltransferase, C-terminal + Type IV conjugative transfer system, protein TraL + Bacteriophage B3, Orf6 + SWIM/SEC-C metal-binding motif protein, PBPRA1643 family + Domain of unknown function DUF4234 + Protein of unknown function DUF4231 + 5-Dehydro-2-deoxygluconokinase + Metaxin, glutathione S-transferase domain + Primosomal replication PriB/PriC + Nuclease-associated modular DNA-binding 1 + Protein of unknown function DUF469 + Uncharacterised protein family YebG + Protein Veg + Phosphate ABC transporter, substrate-binding protein PstS + ABC transporter, Choline, ATP-binding subunit + 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, gammaproteobacteria + Chitinase insertion domain + UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase + Protein of unknown function DUF1003 + Phage P22-like portal protein + Nitrous-oxide reductase + Protein of unknown function DUF1203 + Protein of unknown function DUF2919 + 3,5/4-Trihydroxycyclohexa-1,2-dione hydrolase + Uncharacterised protein family UPF0460 + Concentrative nucleoside transporter, metazoan/bacterial + 6-phosphogluconate dehydrogenase, YqeC-type + CRISPR-associated protein Cas5, Tneap type + Helix hairpin bin domain + D-arabinono-1,4-lactone oxidase + Protein of unknown function DUF2982 + Myc-type, basic helix-loop-helix (bHLH) domain + Protein of unknown function DUF331 + GRAM domain + Tail tube protein + Methyltransferase MtaA/CmuA + Ferrichrome-binding periplasmic protein + Diaminopimelate dehydrogenase, Ddh + Ribosomal biogenesis, methyltransferase, EMG1/NEP1 + Bacteriophage Mu-like, Gp48 + Conserved hypothetical protein CHP02099 + Restriction endonuclease, type II, MunI + Protein of unknown function DUF3052 + Methylmalonyl-CoA mutase small subunit, N-terminal + ABC cobalt transporter + SO1590-like domain + Protein of unknown function DUF2989 + Protein of unknown function DUF3012 + Pilus biogenesis CpaD-related + Putative sugar diacid recognition + Sensor DegS + SprT-like, zinc ribbon domain + Nickel/cobalt homeostasis protein RcnB + Pilus biogenesis, MshL + Phage minor structural protein, N-terminal domain + FaeA-like protein + Ribosomal protein L7Ae conserved site + Sensor protein KdpD, transmembrane domain + Protein of unknown function DUF1841 + Protein of unknown function DUF3100 + ArsR transcriptional regulator + Putative methanogenesis marker 16 metalloprotein + Putative methanogenesis marker 13 metalloprotein + Phosphonoacetaldehyde hydrolase + Restriction endonuclease, type II, EcoRII, N-terminal + PEP-CTERM system-associated, FemAB-related + Restriction endonuclease, type II, NgoFVII + Restriction endonuclease, type II, MamI + Cytochrome oxidase assembly protein 1 + Glycosyl hydrolase family 67, C-terminal + Protein of unknown function DUF4186 + Nif-specific regulatory protein + Domain of unknown function DUF3943 + CRISPR-associated protein Csy3 + Decahaem-associated outer membrane protein, MtrB/PioB + YEATS + 2-methylisocitrate dehydratase AcnD, Fe/S-dependent + Uncharacterised protein family UPF0288, methanogenesis + Phosphonate C-P lyase system, PhnK + Formiminoglutamate deiminase + Methylthioribose kinase + Virulence factor SrfB + Domain of unknown function DUF3463 + Protein of unknown function DUF3149 + Protein of unknown function DUF991 + Protein of unknown function DUF996 + Flagellar protein FliT + Protein of unknown function DUF4336 + Xylose isomerase, actinobacteria + Protein of unknown function DUF3782 + Domain of unknown function DUF3821 + Virulence-related outer membrane protein + Bacteriophage VT1-Sakai, H0025 + Conserved hypothetical protein CHP00661 + CRISPR-associated protein, CXXC-CXXC domain + Enoyl-(acyl-carrier-protein) reductase II, putative + Uncharacterised conserved protein UCP07580 + Transposase, ISC1217 + Translation Initiation factor eIF- 4e-like + Domain of unknown function DUF4041 + Nucleolar GTP-binding protein 1, Rossman-fold domain + CHRD + ABA DEFICIENT 4-like + Transcription regulator, HipB-like + Heme D1 biosynthesis, radical SAM protein NirJ + Spore germination GerAC + Proline-specific peptidase + Phosphogluconate dehydrogenase, NAD-binding, putative, C-terminal + Phytochrome, central region + Pectate lyase + Bacteriophage Mu, Gp16 + Pyroglutamyl peptidase I, Glu active site + Conserved hypothetical protein CHP03097, O-antigen ligase-related + Bacterial toxin, RNase RnlA/LsoA + SigmaK-factor processing regulatory BofA + Uncharacterised protein family Ycf35 + Cellulose/chitin-binding protein, N-terminal + YTV + Anti sigma-E protein RseA, C-terminal + Hypoxanthine-DNA glycosylase + Restriction endonuclease, type II, FokI, C-terminal + Protein of unknown function DUF4380 + UCP01524, winged helix-turn-helix domain + Protein of unknown function DUF3500 + Acyl-CoA thioesterase + PEP-CTERM system TPR-repeat lipoprotein, putative + Protein of unknown function with HXXEE motif + Tetrahydromethanopterin S-methyltransferase subunit A, MtrA + DNA partition complex, ParG + Protein of unknown function DUF4892 + Uncharacterised protein family UPF0259 + Pup ligase/deamidase + Cysteate synthase + Protein of unknown function DUF1749 + Uncharacterised conserved protein UCP006600 + Uncharacterised conserved protein UCP006598 + Salmonella virulence plasmid 65kDa B protein + Na+-dependent bicarbonate transporter superfamily + Conserved hypothetical protein CHP00375 + Anaerobic c4-dicarboxylate membrane transporter + Restriction endonuclease, type II, EcoRI + Outer membrane usher protein + Putative glycyl-radical enzyme activating enzyme YjjW + Uncharacterised protein family UPF0248 + Blue (type 1) copper protein, binding site + ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system + PLAT/LH2 domain + Uncharacterised protein family UPF0231 + Protein of unknown function DUF2225 + Protein of unknown function DUF2391 + Histone H1-like Hc1 + PilZ domain, deltaproteobacteria + RimK-like ATPgrasp N-terminal domain + Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, C-terminal + Restriction endonuclease, type II, BamHI + Sucrose synthase + Low temperature requirement A + Zinc finger, Ogr/Delta-type + Tannase/feruloyl esterase + Protein of unknown function DUF3375 + Beta-galactosidase, domain 2 + Glycine reductase complex selenoprotein A + NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family + DNA repair protein, predicted + Conserved hypothetical protein CHP02450, tryptophan-rich + D-lysine 5,6-aminomutase beta subunit KamE, N-terminal + Phospholipase B-like + Oligogalacturonate-specific porin + Cysteine desulfurase-related + Alpha-galactosidase, NEW1 domain + Domain of unknown function DUF3858 + Domain of unknown function DUF4203 + PEP-CTERM/exosortase system-associated acyltransferase, predicted + Chorismate pyruvate-lyase Rv2949c-like + Catechol 2,3 dioxygenase + Ribosomal protein S28e conserved site + Domain of unknown function DUF1947 + Uncharacterised conserved protein UCP029037 + E3 Ubiquitin ligase, GIDE-type + Glycerate/sugar phosphate transporter, conserved site + UDP-glucuronosyl/UDP-glucosyltransferase + Ethanolamine utilisation EutJ + Protein of unknown function DUF4826 + Ceramidase + PsbP family + Domain of unknown function DUF4399 + Domain of unknown function DUF4398 + Protein of unknown function DUF4403 + Phosphotransferase system, lactose/cellobiose-type IIA subunit + Serine carboxypeptidase, serine active site + GDP dissociation inhibitor + Putative general bacterial porin + Pseudomurein-binding repeat + Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal + Bacteriophage T7, Gp3, endodeoxynuclease I + Protein of unknown function DUF3718 + Thiol-activated cytolysin + 4Fe-4S binding protein, C-terminal + Alpha-1,6-glucosidases, pullulanase-type, C-terminal + Copper resistance lipoprotein NlpE + Transcription activator PspF + Adenosine/AMP deaminase active site + Acetyl/Succinylornithine transaminase family, bacteria + Protein of unknown function DUF2617 + LruC domain + DHHW protein + Hydroxymethylglutaryl-CoA lyase, active site + Natural product biosynthesis luciferase-like monooxygenase domain + Conserved hypothetical protein CHP03545 + Protein of unknown function DUF2119 + Protein of unknown function DUF2279, periplasmic lipoprotein + SUF system FeS cluster assembly regulator + Na+/H+ exchanger + Methyl-coenzyme M reductase, beta subunit + Benzoyl-CoA reductase, bzd-type, O subunit + CRISPR-associated protein APE2256 + Domain of unknown function DUF4921 + N-formylglutamate deformylase + Uncharacterised protein family AF1218 + Protein of unknown function DUF4256 + LssY-like C-terminal domain + Protein of unknown function DUF3137 + Pyrrolysyl-tRNA ligase, C-terminal + DNA-binding RFX-type winged-helix domain + Glycerol-3-phosphate acyltransferase, PlsB + Gas vesicle protein GvpO + Protein of unknown function DUF3313 + Outer membrane protein + Conserved hypothetical protein CHP00155 + NADH dehydrogenase subunit 5, C-terminal + Type VI secretion system-associated, VCA0119 + Mini-chromosome maintenance, conserved site + Sorbitol phosphotransferase enzyme II, N-terminal + DNA-directed RNA polymerase, N-terminal + Phenylacetate degradation probable enoyl-CoA hydratase PaaB + Ribosomal peptide maturation radical SAM protein 1 + TraX + PIN domain toxin + Conserved hypothetical protein CHP00300 + Dihydropteroate synthase-related protein synthase-related protein + ParB-related, ThiF-related cassette, protein C + Beta-N-acetylglucosaminidase + MepB-like + Protein of unknown function DUF2868 + Cysteine-rich CWC + Cytochrome o ubiquinol oxidase subunit IV + Arrestin-like, N-terminal + Cobaltochelatase subunit, putative + Protein of unknown function DUF3037 + FkbH domain + Domain of unknown function DUF4350 + Methyl-coenzyme M reductase, protein D + Protein of unknown function DUF3334 + Plasmid encoded RepA protein + GMP reductase + Aminodeoxyfutalosine synthase + Phycobilisome linker domain + WW domain + Aconitase, mitochondrial-like + Plasmid segregation protein ParM/StbA + Calcineurin-like phosphoesterase, N-terminal + Archaeal/bacterial/fungal rhodopsins + Uncharacterised conserved protein UCP005642, methanogenesis + Ferredoxin-type protein NapF + Ribosomal protein L34Ae + Putative ABC transporter periplasmic binding protein PhnD-like + Alcohol dehydrogenase, insect-type + 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal + 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH + Exosortase H, IPTLxxWG-CTERM-specific + Zinc finger, ZPR1-type, subgroup + Conserved hypothetical protein CHP04014, B12-binding/radical SAM-type + Domain of unknown function DUF2236 + Protein of unknown function DUF485 + Glutamate mutase E subunit, C-terminal domain + Ribosomal protein S17e, conserved site + Ethanolamine utilisation EutQ + HD-related protein + Bacteriophage tail protein Gp41, putative + Pullulanase, carbohydrate-binding module 41 + Dpy-19/Dpy-19-like + Protein of unknown function DUF2956 + Protein of unknown function DUF2939 + Glycosyl hydrolase family 67, catalytic domain + YtkA-like domain + Integral membrane protein YccS, N-terminal + Allophanate hydrolase + Peptidase S51, cyanophycinase + 6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase + Conserved hypothetical protein CHP03492 + IMP cyclohydrolase + Protein of unknown function DUF968 + TfuA-like, core + Protein of unknown function DUF2090 + Stimulus-sensing domain + Cytochrome c, class ID + Peptidase A31, hydrogenase expression/formation protein + Protein of unknown function DUF2999 + Lipase, secreted + Zinc finger, CCHC-type + Protein of unknown function DUF1036 + Radical SAM, TatD-associated + Protein of unknown function DUF413 + Aspartate 1-decarboxylase, pyridoxal-dependent + Invasin, domain 3 + Chs5p-Arf1p binding + SPW repeat + Sterol-sensing domain + Protein of unknown function DUF4914 + Aerobic respiration control sensor protein ArcB, transmembrane domain + Conserved hypothetical protein CHP02147 + CRISPR associated protein Csc3 + Domain of unknown function DUF695 + [FeFe]-hydrogenase maturation HydG, radical SAM + ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC + CRISPR-associated protein Cas1, DVULG subtype + Thiazole biosynthesis ThiH + Methyltransferase domain, putative + Protein of unknown function DUF3126 + Prenyl protease-related + Protein of unknown function DUF3630 + Protein of unknown function DUF3265 + Plasminogen-binding protein PgbA, N-terminal + PfaD family protein + FeS assembly SUF system protein SufT, putative + Biofilm formation YgiB + Protein of unknown function DUF1192 + Protein of unknown function DUF3616 + Protein of unknown function DUF3732 + Protein of unknown function DUF2226 + Restriction endonuclease, type II, Bsp6I + Bromodomain + Alternate ATP synthase, F1 complex, subunit alpha + Protein of unknown function DUF4404 + Type IV secretion system, VirB5 + NIDO domain + Putative exonuclease, DNA ligase-associated + Strawberry notch, helicase C domain + Acetyl-CoA C-acyltransferase FadA + PhoP regulatory network protein YrbL + Formiminoglutamase + Phage tail fibre protein + Protein of unknown function DUF3320 + Ferritin-like protein + Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase + PAS fold-2 + PucC-related + Protein of unknown function DUF1656 + Helicase, superfamily 3, single-stranded DNA/RNA virus + CRISPR-associated protein, NE0113 + TonB-dependent haemoglobin/transferrin/lactoferrin receptor + Glucose-1-phosphate adenylyltransferase, GlgD subunit + ATPase, V0 complex, c subunit + Conjugative relaxase, N-terminal + RNA polymerase, Rpb5, N-terminal + Putative methanogenesis marker protein 2 + Usg-like + Putative purine nucleotide phosphorylase + BA14k family + Protein of unknwon function DUF3008 + Protein of unknown function DUF2897 + Zinc finger, PARP-type + Cobalamin-independent methionine synthase + Acetyl-S-ACP:malonate ACP transferase + Iron-sulphur-dependent L-serine dehydratase beta subunit + Protein of unknown function DUF3335 + Peptidase A26, omptin + Myoviridae tail sheath stabiliser + Photosystem I PsaA/PsaB + Two pore domain potassium channel + PD(D/E)XK endonuclease + Aliphatic sulfonates-binding protein + Domain of unknown function DUF642 + Protein of unknown function DUF995 + Protein of unknown function DUF600 + LEM/LEM-like domain + Peptidase family M60 domain + Protein of unknown function DUF3560 + CoB--CoM heterodisulphide reductase, subunit B + DNA polymerase III, psi subunit + Protein of unknown function DUF459 + Cell division protein ZapC + 3-oxoacyl-(acyl-carrier-protein) reductase, putative + Ribosomal protein S8e, conserved site + Ribonuclease III, archaeal + Dinitrogenase iron-molybdenum cofactor, N-terminal + Tyrosyl-DNA phosphodiesterase I + Protein of unknown function DUF4492 + Bacillus/Clostridium Ger spore germination protein + Domain of unknown function DUF4071 + Protein of unknown function DUF3240 + Uncharacterised domain, helicase/relaxase, putative + Accessory gene regulator B + Doublecortin domain + Maltose transport system permease protein MalF, P2 domain + Domain of unknown function DUF4443 + Control of competence regulator ComK, YlbF/YmcA + RTX toxin-activating protein C, bacteria + Domain of unknown function DUF4032 + Protein of unknown function DUF1367 + YejL-like domain + 2-hydroxymuconic semialdehyde dehydrogenase + Ribosomal S24e conserved site + YfbU, helix-hairpin domain + Protein of unknown function DUF4128 + RNA chaperone ProQ, C-terminal + Cytochrome o ubiquinol oxidase subunit II + DNA polymerase III-theta, bacterial + Protein of unknown function DUF1475 + Futalosine hydrolase + Transcription regulator QacR, C-terminal + RNA ligase T4 Rnl1, N-terminal + Domain of unknown function DUF4397 + Copper type II, ascorbate-dependent monooxygenase-like, C-terminal + Protein of unknown function DUF5063 + Sulphate ABC transporter, permease protein CysT + Myoviridae, GpU + Protein of unknown function DUF3721 + Nitrogenase molybdenum-iron protein beta chain, N-terminal + Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit + Phage shock protein, PspA + Conserved hypothetical protein CHP03987 + Peptide-modifying radical SAM enzyme putative, AF0577 + Uncharacterised protein family UPF0208 + Antirestriction protein + Protein of unknown function DUF2170 + Gram-positive LPXTG cell wall anchor + Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase + Restriction endonuclease, type II, Eco47II + Putative O-antigen polymerase + Zinc finger, RING-type + Lycopene cyclase domain + Endoplasmic reticulum resident protein 29, C-terminal + Regulator of ribonuclease activity A, gammaproteobacteria + Protein of unknown function DUF1924 + Hydroxymethylpyrimidine transporter CytX + Conserved hypothetical protein CHP02646 + Thymidine phosphorylase + Streptogrisin prodomain + MauM/NapG ferredoxin-type protein + Bacterial virulence factor lipase, N-terminal domain + Ribose-1,5-bisphosphate isomerase, e2b2 family + Protein of unknown function DUF922 + 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase + Domain of unknown function DUF1535 + DNA replication regulator, HobA + Polysaccharide pyruvyl transferase, CsaB + Catechol dioxygenase, N-terminal + Fructose-2,6-bisphosphatase + Protein of unknown function DUF4935 + Protein of unknown function DUF2093 + Protein of unknown function DUF2095 + Bacteriophage P22, Gp10, DNA-stabilising + Replication-associated protein G2P, N-terminal + Protein of unknown function DUF3135 + Protein of unknown function DUF4279 + Cytochrome c nitrite reductase, small subunit + Glutaredoxin, GrxA + Glutaredoxin domain + Malonyl-[acyl-carrier protein] O-methyltransferase BioC + Zinc finger, MYM-type + 2-isopropylmalate synthase + Domain of unknown function DUF4347 + Cobalamin biosynthesis central region + Putative membrane-bound dehydrogenase + NifQ + Beta-1,3-glucanase, N-terminal + Protein of unknown function DUF2787 + Domain of unknown function DUF4329 + Pilus assembly TraK + Protein of unknown function DUF3332 + CRISPR-associated protein GSU0053 + Frataxin conserved site + Betaine aldehyde dehydrogenase + Quinohemoprotein amine dehydrogenase, alpha subunit domain III + Putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE + Putative 4-mercaptohistidine N1-methyltranferase, OvoA C-terminal domain + Protein of unknown function DUF3283 + Zinc finger, LIM-type + Prokaryotic E2 family A + Protein of unknown function DUF1059 + Putative nucleotidyltransferase + Domain of unknown function DUF2169 + PQQ-dependent catabolism-associated CXXCW motif + ZinT domain + Protein of unknown function DUF3034 + Cd(II)/Pb(II)-responsive transcriptional regulator + VirC1 + Uncharacterised protein family UPF0311 + Fatty oxidation complex, alpha subunit FadB + Putative cellulase + ATPase, A1A0, subunit H + Tryptophan RNA-binding attenuator protein domain + Septum formation inhibitor MinC, N-terminal + 3,4-dihydroxyphenylacetate 2,3-dioxygenase + Uncharacterised protein family UPF0352 + Chorismate mutase, T-protein + PqqD family protein, HPr-rel-A system + Prokaryotic chromosome segregation/condensation protein MukE + Restriction endonuclease, type II, NgoPII + Fructose-1,6-bisphosphatase class 3 + TQO small subunit DoxD + Protein of unknown function DUF3465 + Domain of unknown function DUF5077 + Integrase catalytic domain, putative + Putative integrase, N-terminal + [NiFe]-hydrogenase maturation factor HyaE + Domain of unknown function DUF1993 + Conserved hypothetical protein CHP02096 + Chitobiase C-terminal domain + Protein-tyrosine phosphatase, SIW14-like + Frag1/DRAM/Sfk1 + Protein of unknown function DUF4054 + Domain of unknown function DUF1206 + Protein Gp5, N-terminal OB-fold domain + SynChlorMet cassette protein ScmC + Protein of unknown function DUF2239 + Protein of unknown function DUF3866 + Protein of unknown function DUF2496, YbaM-related + KaiA/RbsU helical domain + Hedgehog protein, Hint domain + Protein AmpE + PKD/REJ-like domain + Rhomboid protease GlpG + Glycoside hydrolase, family 13, N-terminal Ig-like domain + Radical SAM enzyme, MSMEG0568 + Protein of unknown function DUF432 + Helicase-associated + Domain of unknown function DUF1902 + Uncharacterised conserved protein UCP010219 + Protein of unknown function DUF3224 + Protein GvpH + Protein of unknown function DUF1375 + Methionine repressor MetJ domain + Protein of unknown function DUF1849 + Carboxylate/Amino Acid/Amine Transporter + LL-diaminopimelate aminotransferase + TMEM220 protein + Putative beta barrel porin-7 + Multi-ubiquitin domain + Methyltransferase regulatory domain, predicted + Protein of unknown function DUF3006 + Alpha-N-acetylglucosaminidase, tim-barrel domain + PRMT5, oligomerisation domain + rRNA-processing protein Fcf1/Utp23 + Protein of unknown function DUF1864 + DNA helicase IV, N-terminal domain + CRISPR-associated RAMP BGP1436 + Carbohydrate binding module, xylan-binding domain + Aspartate 4-decarboxylase + Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal + Domain of unknown function DUF4328 + Putative phage integrase + Protein of unknown unction DUF1444 + SLC12A transporter, C-terminal + Membrane protein GlpM/YdgC + N-acetyl-gamma-glutamyl-phosphate reductase, type 2 + CRISPR-associated protein Cas1, YPEST subtype + Protein of unkown function DUF2523 + ATP adenylyltransferase, C-terminal + Plasmid recombination enzyme + Transcription attenuation protein MtrB + Type IV conjugative transfer system protein TraV + Protein of unknown function DUF1107 + Domain of unknown function DUF2510 + Phosphotransferase system, glucitol/sorbitol-specific IIA component + Protein of unknown function DUF3545 + Domain of unknown function DUF3322 + Serine proteases, V8 family, serine active site + Anthranilate synthase component I, archaeal type + Haem NO binding associated + Alkylmercury lyase + Ribosomal protein S25 + Protein of unkown function DUF3268 + Energy-coupling factor transporter ATP-binding protein EcfA2 + Type VI secretion system peptidoglycan-associated domain + Protein of unknown function DUF1488 + Mobile mystery protein A + Protein of unknown function DUF3144 + Transcription antitermination protein RfaH + RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 + Protein of unknown function DUF3622 + Peptidase M17, peptidase B + L-lactate dehydrogenase + D-xylose ABC transporter, substrate-binding protein + Rhamnose ABC transporter, substrate-binding protein RhaS + LacY/RafB permease family + AMP phosphorylase + Ribulose bisphosphate carboxylase, type III + Der GTPase activator + Manganese catalase + Peptidase M3B, oligoendopeptidase-related + Surface carbohydrate biosynthesis protein + Protein of unknown function DUF3761 + Formate transporter FocA, putative + Putative phage abortive infection protein + N-carbamoylputrescine amidase + Conserved hypothetical protein CHP02588 + Omega-3 polyunsaturated fatty acid synthase-like + Uncharacterised protein family, basic secretory protein + Alpha-N-acetylglucosaminidase, C-terminal + LydA-like holin + Protein of unknown function DUF2199 + Bacteriophage T4, Gp32, single-stranded DNA-binding + Conserved hypothetical protein CHP02117 + GAD-related + P-type ATPase, subfamily IIIA + Archaeal dihydromethanopterin reductase + Progressive ankylosis + Zinc-ribbon domain, bacteria + PD-(D/E)XK nuclease + 4-carboxymuconolactone decarboxylase + Ribonuclease M5, C-terminal domain + Sporulation stage III, transcriptional regulator SpoIIID + Cytochrome o ubiquinol oxidase, subunit III + Protein of unknown function DUF3482 + Tyrosinase copper-binding domain + L-alanine exporter AlaE + ATP-dependent DNA ligase, PP_1105 family + Domain of unknown function DUF4377 + Streptothricin acetyltransferase + Protein of unknown function DUF4260 + YaiO family, OMP domain + Uncharacterised conserved protein UCP037052 + NUDIX hydrolase, NudL, conserved site + Protein of unknown function DUF4857 + Siphovirus Gp157 + Domain of unknown function DUF835 + Photosystem antenna protein-like + Domain of unknown function DUF4842 + Polycystic kidney disease type 2 protein + Oxygen oxidoreductase covalent FAD-binding site + Fis1, C-terminal tetratricopeptide repeat + Tryptophan/tryrosine permease, conserved site + Glutamate mutase sigma subunit + Flavodoxin, short chain + ADP-specific phosphofructokinase/glucokinase + Peptidase M9A/M9B, collagenase, bacterial + Aspartyl-phosphate phosphatase Spo0E-like + Tetratricopeptide TPR-3 + Protein of unknown function DUF2516 + Extracellular protein + Nitrite reductase, copper-type + Malate synthase A + Uncharacterised protein family YfdX + Methionine repressor MetJ + Protein of unknown function DUF4152 + ATP-dependent DNA helicase PcrA + Bacteriophage T4, Gp14, neck protein + Integrating conjugative element protein, PFL4669 + C-terminal AAA-associated domain + D-lactate dehydrogenase, membrane binding, C-terminal + Anti-sigma factor RsgI, N-terminal + Conserved hypothetical CHP02185, integral membrane + Aminoglycoside-2''-adenylyltransferase + Protein of unknown function DUF4760 + M60-like domain, N-terminal + Pseudaminic acid biosynthesis-associated methyltransferase + 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase + Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase + Citrate lyase ligase, C-terminal + AT hook, DNA-binding motif + Protein of unknown function DUF366 + Aminoglycoside/hydroxyurea antibiotic resistance kinase + Cholinesterase + Fn3-like domain + Pyrrolysine biosynthesis protein PylB + Fibrillarin, conserved site + Major royal jelly protein/protein yellow + Domain of unknown function DUF4457 + ParB-like nuclease, C-terminal domain + Bacteriophage tail completion protein R + Lysine methyltransferase + Hexokinase, C-terminal + Putative sugar O-methyltransferase + Conserved hypothetical protein CHP02301 + Phage baseplate assembly protein V/Gp45 + Methyltransferase Mtx, subunit X + Cysteine protease Prp + DNA primase DnaG, C-terminal helicase-binding domain + Domain of unknown function DUF155 + Benzoyl-CoA reductase, bzd-type, Q subunit + Aromatic acid exporter family member 1 + Cwf19-like, C-terminal domain-1 + [FeFe]-hydrogenase H-cluster maturation GTPase HydF + Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase + YadA-like, C-terminal + Protein of unknown function DUF2299 + Protein of unknown function DUF2960 + Malate dehydrogenase enzyme, N-terminal + Mitochondrial PGP phosphatase + Protein of unknown function DUF2612 + Pentraxin-related + CRISPR-associated protein, TM1793 + Glycosyl hydrolase family 115 + Ribosomal protein L19/L19e conserved site + Glucodextranase, N-terminal + Pyridoxine kinase + Indoleamine 2,3-dioxygenase + Uncharacterised protein family YfcL + Glycosyltransferase AglJ + Hydrophobe/amphiphile efflux-3 HAE3 + Legume lectin domain + Flagellar, putative + Protein DcrB + Putative methanogenesis marker protein 10 + Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site + Protein of unknown function DUF417 + Domain of unknown function DUF1794 + ENTH/VHS + Haemin-degrading HemS/ChuX domain + Transposon Tn7 transposition protein TnsD, C-termianl + Domain of unknown function DUF4168 + Protein of unknown function DUF3089 + Molybdopterin guanine dinucleotide-containing S/N-oxide reductase + Phosphoadenosine phosphosulphate reductase CysH + Phenylacetate-CoA ligase + Uncharacterised conserved protein UCP022079 + [FeFe]-hydrogenase maturation HydE, radical SAM + Abortive phage resistance protein AbiGi + Regulator of RNA terminal phosphate cyclase + Protein of unknown function DUF2987 + Protein of unknown function DUF3383 + Arsenite oxidase, small subunit + RNA polymerase sigma-70 ECF-like, Rhodopirellula baltica + Protein of unknown function DUF2336 + Bax inhibitor 1, conserved site + Methanol-cobalamin methyltransferase, B subunit + Acyltransferase, WS/DGAT/MGAT + RNA polymerase sigma-X type + Alpha/beta-hydrolase, N-terminal domain + Protein kinase A anchor protein, nuclear localisation signal domain + Putative multidrug resistance efflux transporter + Coronovirus spike glycoprotein, heptad repeat 2 domain + HmuY protein + Pyruvate formate-lyase activating enzyme + Protein of unknown function DUF3501 + Snf7 family + Alpha/beta-hydrolase, catalytic domain + Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative + DNA ligase D, ligase domain + Protein of unknown function DUF1496 + Protein of unknown function DUF2103, metal-binding + Replication-associated protein G2P, C-terminal + Flagellar transcriptional activator FlhC + Uncharacterised protein family A0KLC6 + Protein of unknown function DUF3141 + Protein of unknown function DUF3626 + Kanamycin nucleotidyltransferase, C-terminal + Putative selenate reductase YgfK + Putative nitrogen fixation protein + Thg1 C-terminal domain + Fas apoptotic inhibitory molecule 1 + Uncharacterised protein family YnzE + NLPC/P60, N-terminal domain + Uncharacterised conserved protein UCP008210 + Replication factor A, C-terminal + Domain of unknown function DUF4965 + Chloramphenicol phosphotransferase-like + Protein of unknown function DUF3574 + dsDNA mimic, putative + Bacteriophage 186, CII + Protein of unknown function DUF1641 + Acireductone dioxygenase ARD family + [FeFe]-hydrogenase system regulator TM1266 + Chorismate mutase, gammaproteobacteria + Protein of unknown function DUF992 + Uncharacterised protein family UPF0325 + Protein of unknown function DUF1428 + Nitrogenase molybdenum-iron protein beta chain + Nitrogenase molybdenum-iron protein alpha chain + Acidobacterial duplicated orphan permease + Cobalamin (vitamin B12) biosynthesis CobF, precorrin-6A synthase + Protein of unknown function DUF2855 + Variant SH3 domain + Protein of unknown function DUF4269 + Uridine phosphorylase + 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase + Small acid-soluble spore protein, alpha/beta-type, conserved site + Vacuolar fusion protein Mon1 + Glycosyl hydrolases 36 + Malate synthase, conserved site + T4 endonuclease V + Phytochrome + rRNA methyltransferase AviRa + PA2201-like, C-terminal + Flagellar filament outer layer protein FlaA + Transferrin-binding protein, C-lobe/N-lobe beta barrel domain + Beta/gamma crystallin + tRNA(Met) cytidine acetyltransferase TmcA, tRNA-binding domain + C2 domain + G8 domain + Bacteriophage T4, Gp59, helicase assembly protein, N-terminal + Conserved hypothetical protein CHP03503 + Domain of unknown function DUF892 + Uncharacterised protein family HutD/Ves + Domain of unknown function DUF4990 + Domain of unknown function DUF4476 + Sulphite reductase (NADPH) hemoprotein, beta subunit + D-serine ammonia-lyase + Protein of unknown function DUF473 + 2,3-diaminopropionate biosynthesis protein SbnA + Ribosomal S4P (gammaproteobacterial) + Bacteriophage Mu, Gp27 + Protein of unknown function DUF2127 + Archaeal flagella protein FlaD/E domain + Ribosomal protein L40e + Uncharacterised conserved protein UCP014543 + Sugar transport protein + Cationic amino acid transporter, C-terminal + Alpha-ribazole phosphatase, CobZ + Ribosomal protein L22e + Uncharacterised protein family UPF0324, bacteria + Nif11 domain + Fumarate reductase, subunit C + 6-oxocyclohex-1-ene-1-carbonyl-CoA hydrolase + Sulphite reductase [NADPH] flavoprotein, alpha chain + Uncharacterised conserved protein UCP019164, methanogenesis + Orn/Lys/Arg decarboxylase, N-terminal + Protein of unknown function DUF1840 + Domain of unknown function DUF1851 + Domain of unknown function DUF4189 + Blue (type 1) copper protein, plastocyanin-type + Oligosaccharyl transferase complex, subunit OST3/OST6 + Phage protein (N4 Gp49/phage Sf6 gene 66) family + Phenol hydroxylase subunit + Benzoyl-CoA-dihydrodiol lyase + Benzoyl-CoA oxygenase/reductase, BoxA protein + Benzoyl-CoA oxygenase, B subunit + Ribosomal protein S30 + Protein of unknown function DUF899, thioredoxin-like + Domain of unknown function DUF4833 + Cyclic peptide transporter + Mini-chromosome maintenance complex protein 4 + Chitinase A N-terminal + Calcium/calmodulin-dependent protein kinase II, association-domain + Proteinase inhibitor I13, potato inhibitor I + Urea carboxylase-associated protein 2 + ATPase, secretion system, PEP-CTERM, predicted + Phage protein of unkonwn function + Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal + MbtH-like protein + Ethanolamine permease + Domain of unknown function DUF4261 + Domain of unknown function DUF4178 + Protein of unknown function DUF3084 + Domain of unknown function DUF1713 + L-lysine 6-transaminase + HNS-dependent expression A/B + Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site + CRISPR-associated endonuclease Cas9, REC lobe + Mitochondrial carrier domain + Protein of unknown function DUF1571 + Bacteriophage T4, Gp59, helicase assembly protein, C-terminal + Phosphotransferase system, enzyme II sorbitol-specific factor + Domain of unknown function DUF3870 + Type VI secretion system (T6SS), amidase effector protein 4 + AmiS/UreI transporter + Conjugative transposon, TraO + Protein of unknown function DUF2860 + Protein of unknown function DUF3103 + Bacteriocin-type signal sequence + Putative methanogenesis marker domain 9 + Antitoxin VapB-like + RNA polymerase sigma-B/F/G type + Integrin beta subunit, VWA domain + TRSP domain + Protein of unknown function DUF2098 + Glutathione reductase, eukaryote/bacterial + Protein of unknown function DUF3955 + Protein of unknown function DUF2974 + Creatinine amidohydrolase + DNA phosphorothioation-dependent restriction protein DptG + Bacteriophage P2, GpM + Translation elongation factor P-like, YeiP + Bacteriophage HP1, Orf28 + Bacteriophage HP1, Orf23 + Protein of unknown function DUF2569 + Anti-sigma-F factor NrsF + Protein of unknown function DUF2568 + DNA-directed RNA polymerase, helix hairpin domain + H/ACA ribonucleoprotein complex, subunit Nop10 + Transcription regulator HTH, APSES-type DNA-binding domain + KaiB domain + Protein of unknown function DUF2194 + Integrating conjugative element protein, PFL4697-type + Zinc finger-XS domain + Protein of unknown function DUF378 + Phage portal protein PBSX family + Bacteriophage Mu, Gp46 + Transcription regulator PrtN + Phasin, subfamily 3 + Putative formate dehydrogenase, TAT signal-containing + Putative transmembrane family 234 + Protein of unknown function DUF2850 + Hypothetical protein TM1646-like domain + Peptidase M9, collagenase, N-terminal domain + MatP, C-terminal ribbon-helix-helix domain + Conserved hypothetical protein CHP03083, actinobacterial-type + Fumarate reductase, subunit D + Protein of unknown function DUF3083 + Protein of unknown function DUF997 + Cytochrome b561/ferric reductase transmembrane + Domain of unknown function DUF2023 + Protein of unknown function DUF3618 + Protein of unknown function DUF2026 + Protein of unknown function DUF2600 + Domain of unknown function DUF3991 + Rhamnose isomerase-related + Domain of unknown function DUF4375 + Methylthioribulose-1-phosphate dehydratase + LuxT regulator, helix hairpin domain + MIT + Type IV secretion system protein VirB11 + Domain of unknown function DUF4959 + Integrating conjugative element protein, PFL4704 + Cellulose synthase operon C, C-terminal + TRASH transcription regulator C-terminal, archaeal + Ribonucleotide reductase alpha chain + RNA polymerase sigma-Z type + Protein of unknown function DUF2607 + Insecticide toxin TcdB middle/C-terminal + Homotrimeric ring hydroxylase, catalytic domain + Metallothionein, family 14, prokaryote + Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales + Ribosomal protein L39e, conserved site + Immunoglobulin-like domain + Uncharacterised protein family UPF0212 + Proteasomal ATPase, OB/ID domain + Endo-1,3(4)-beta-glucanase + Type-F conjugative transfer system mating-pair stabilisation protein TraN + Protein of unknown function DUF4144 + Protein of unknown function DUF1634 + Type II restriction enzyme NlaIII/ICEA1 + Tail accessory factor GP4 + Malate dehydrogenase, type 1 + HAD-superfamily hydrolase, subfamily IA, CTE7 + Lipase chaperone + L-methionine gamma-lyase + Domain of unknown function DUF1937 + Protein of unknown function DUF3011 + Domain of unknown function DUF4132 + Uncharacterised protein family, YqcI/YcgG + Protein of unknown function DUF535 + Protochlamydia outer membrane protein + Domain of unknown function DUF4980 + Fructose-bisphosphate aldolase class-I active site + Hemocyanin/hexamerin + Lacto-N-biose phosphorylase, central domain + Integral membrane protein TerC, riboswitch-linked + Domain of unknown function (DUF4240 + Porin, gammaproteobacterial + Ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent + Replication-associated protein G2P + FecR, N-terminal + Plasmid replicase, bacterial + C(7)-type cytochrome triheme domain + Phosphonopyruvate decarboxylase + Putative ABC exporter + Protein of unknown function DUF5005 + Protein of unknown function DUF4364 + Laminin IV + Protein of unknown function DUF1145 + Mutator MutX protein + Protein of unknown function DUF4868 + Glutamate--cysteine ligase GshA + Membrane-bound tetrahaem cytochrome TorC/YecK + CagE, TrbE, VirB component of type IV transporter system + Leucine rich repeat variant + CAT RNA-binding domain + Dimethlysulfonioproprionate lyase DddL + Extracellular lipase, Pla-1/cef family + Lanthionine synthetase C-like + Bacteriophage abortive infection AbiH + Helicase SMUBP-2/Hcs1-like + Protein of unknown function DUF4164 + 2-dehydro-3-deoxy-phosphogluconate aldolase + CspD, cold shock + NlpE, C-terminal OB domain + Protein of unknown function DUF1391 + DNA circulation, N-terminal + Peptidase M11, gametolysin + SseB protein, C-terminal + Glycosyl transferase family 29 + Pectinesterase, Asp active site + Protein of unknown function DUF3440 + Bacteriophage TLS, TfmB + Ribosomal protein L15e, conserved site + Zinc finger, LSD1-type + XPA C- terminal + Protein of unknown function DUF4330 + Glycoside hydrolase, family 52 + Virulence factor membrane-bound polymerase, C-terminal + Protein of unknown function DUF1240 + Type III secretion system outer membrane pore YscC/HrcC + NADH:ubiquinone/plastoquinone oxidoreductase, chloroplast chain 5, C-terminal + Quinohemoprotein amine dehydrogenase, alpha subunit, domain 2 + Sortase, proteobacterial type + Cofactor-binding repeat, putative + Chorismate mutase, periplasmic + Mitochondrial apoptosis-inducing factor, C-terminal domain + Class III signal peptide motif + Phage-integrase repeat unit + Domain of unknown function DUF5017 + Protein of unknown function DUF2934 + Protein of unknown function DUF2931 + Dihydroorotase-like, bacterial + N-acetylmuramidase + Bacteriophage lambda, GpL, minor tail + High-affinity branched-chain amino acid transport system permease, LivHM, N-terminal + Protein of unknown function DUF1796 + Ribose-5-phosphate isomerase, C-terminal + Beta-glucanase + Iodothyronine deiodinase + 5-histidylcysteine sulfoxide synthase + Pyrrolysyl-tRNA ligase, N-terminal + Protein of unknown function DUF1361 + Conserved hypothetical protein CHP00061 + Formate dehydrogenase, transmembrane + Mycobacterium phage PG1, Gp7 + Domain of unknown function DUF2294 + DNA mismatch repair protein MutH + Methyl coenzyme M reductase, alpha subunit + Protein of unknown function DUF1097 + Protein of unknown function DUF483 + Tartrate dehydrogenase + Pab87 octamerisation domain + 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase + Small acid-soluble spore protein, alpha/beta-type + CRISPR locus-related putative DNA-binding protein Csa3 + Bacillithiol biosynthesis thiol disulphide oxidoreductase, YpdA + Mu-type HTH domain + 3-dehydroquinate dehydratase, active site + Cytochrome b5, heme-binding site + Ubiquitin-related modifier 1 + Squalene synthase HpnC + Copper type II, ascorbate-dependent monooxygenase, N-terminal + Domain of unknown function DUF2846 + Protein of unknown function DUF2829 + Ribonucleotide reductase N-terminal + CRISPR-associated DxTHG protein + Ribulose bisphosphate carboxylase small chain, domain + PIN-domain ribonuclease + Inositol oxygenase + Maltose operon periplasmic + Bacteriophage lambda, GpM, minor tail + Transcriptional regulator + GINS subunit, domain A + Epoxide hydrolase, N-terminal + Conserved hypothetical protein CHP04442 + TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase + Protein of unknown function DUF1919 + Protein of unknown function DUF1917 + Protein of unknown function DUF4250 + Porin PorA + Protein of unknown function DUF3293 + Copper-resistance protein CopA + Protein of unknown function DUF1579 + Atu2299-like domain + Uncharacterised protein family UPF0146 + Phage phiEco32-like COOH-NH2 ligase-type 2 + Alcohol acetyltransferase/N-acetyltransferase + Glycoside hydrolase family 9, His active site + Killing trait, RebB + Uncharacterised protein family UPF0473 + Conserved hypothetical protein CHP04083, radical SAM + Succinate CoA transferase + N-alpha-acetyl diaminobutyrate deacetylase DoeB + Ectoine utilization protein EutD + Protein of unknown function DUF4434 + Bacteriophage rv5, Orf52 + Protein of unknown function DUF1449 + TnsA endonuclease C-terminal + Dinitrogenase reductase ADP-ribosyltransferase + Translation repressor RegA + 2-oxoisovalerate dehydrogenase, E1 alpha subunit, N-terminal domain + Purine nucleoside permease + Protein of unknown function DUF3793 + Ribonucleoside-triphosphate reductase activating, anaerobic + Protein of unknown function DUF977 + Chlorophyll a/b binding protein domain + Protein of unknown function DUF3634 + Phosphoheptose isomerase + G-protein, beta subunit + Tyrosine phenol-lyase + Dihydroorotate dehydrogenase A, chain A, domain 2 + Putative ccm operon protein + FCP1 homology domain + Mitochondrial inner membrane protein Mitofilin + Ribosomal RNA small subunit methyltransferase F, first C-terminal domain + Thiosulphate:quinone oxidoreductase small subunit DoxA + Sorbitol phosphotransferase enzyme II, C-terminal + Cyanophycin synthetase + Bacteriophage HP1, Orf24 + Protein of unknown function DUF3311 + Alternate ATP synthase, F1 complex, subunit gamma + 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain + Gamma-aminobutyric acid A receptor/Glycine receptor alpha + Protein of unknown function DUF5058 + Capsid scaffolding protein GpO + Staphylococcal AgrD + Protein of unknown function DUF2071 + 30S ribosomal protein + Protein of unknown function DUF4156 + D-lactate dehydrogenase, C-terminal subdomain 2 + Domain of unknown function DUF4401 + Alpha galactosidase A, C-terminal beta-sandwich domain + HprK-related kinase A + Enterobacterial TraT complement resistance + Bacteriophage P2, GpN, major capsid + Protein of unknown function DUF3326 + Carotenoid oxygenase + Ferredoxin III 4[4Fe-4S], nif-specific + Ribosomal protein S3Ae, conserved site + Domain of unknown function DUF1540 + Protein of unknown function DUF736 + Glutamine synthetase, type III + Non-histone chromosomal MC1 + TROVE domain + Alpha-2-macroglobulin, conserved site + Protein of unknown function DUF1266 + Translation initiation factor, beta propellor-like domain + MEKHLA + RNA polymerase sigma-H type + Protein of unknown function DUF3303 + Domain of unknown function DUF4180 + Domain of unknown function DUF4179 + Streptococcus phage 7201, Orf34, N-terminal + O-succinylhomoserine (thiol)-lyase + Capsule biosynthesis phosphatase + Nitrogenase molybdenum-iron cofactor biosynthesis protein + Peroxiredoxin-like FAM213/AAED1 + Choice-of-anchor B domain + Superinfection exclusion protein B + Metallo-carboxypeptidase, C-terminal domain + Protein of unknown function DUF4272 + Putative CRISPR-associated protein, VVA1548 family + Mpv17/PMP22 + Periplasmic nitrate reductase, large subunit + MucBP domain + Conserved hypothetical protein CHP03858, luciferase-like monooxygenase, putative + Conserved hypothetical protein CHP03843 + Basic-leucine zipper domain + Tubulin + Nodulation protein Z + Domain of unknown function DUF2431 + Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha + Uncharacterised conserved protein UCP019262 + B-block binding subunit of TFIIIC + Photosystem II PsbK + ATP:guanido phosphotransferase, N-terminal + Prion/Doppel protein, beta-ribbon domain + Haem oxygenase-like + Squalene cyclase + Competence protein ComK + TerY-C metal binding domain + Protein of unknown function DUF2441 + Uncharacterised protein family UPF0285, methanogenesis + Conserved hypothetical protein CHP03979 + Putative Flagellin, Flp1-like domain + Putative DNA-binding protein, HU-related + Protein of unknown function DUF4127 + LDLR class B repeat + Diaminopropionate ammonia-lyase, subgroup + Ribosomal protein L37e + Phenol hydroxylase + Bacteriophage CI repressor, C-terminal + Putative NADH-ubiquinone oxidoreductase chain E + Mycolic acid cyclopropane synthase-like domain + Primosomal replication protein PriB + Protein of unknown function DUF1207 + SynChlorMet cassette radical SAM/SPASM protein ScmF + Protein of unknown function DUF2913 + Conserved hypothetical protein CHP02421, QEGLA + Protein of unknown function DUF3861 + 6-phosphofructo-2-kinase + Caa(3)-type oxidase, subunit IV + Protein of unknown function DUF2500 + Proteasome activator pa28, C-terminal domain + Protein of unknown function DUF2274 + Solitary outer membrane autotransporter beta-barrel domain + Protein of unknown function DUF2945 + Transcription factor TFE, archaea + Cyanuric acid hydrolase/Barbiturase + Protein of unknown function DUF979 + Protein of unknown function DUF3658 + YlqD protein + DKNYY family + Uncharacterised protein family MJ1658 + Protein of unknown function DUF969 + Glycosyl transferase, family 31 + Polyketide-type polyunsaturated fatty acid synthase, PfaA + Peptidase, metallopeptidase M10/M27/M57 + FAD-containing D-sorbitol dehydrogenase small subunit + Phox homologous domain + Phage tail assembly chaperone protein + Peptidase C19, ubiquitin carboxyl-terminal hydrolase + Uncharacterised protein family UPF0297 + RNA polymerase Rpb1, domain 7 + Protein glycosylation ligase domain + Protein of unknown function DUF3540 + Acetyl-CoA C-acyltransferase FadI + UrcA family protein + Protein of unknown function DUF4831 + Cytochrome f + 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 2 + Protein of unknown function DUF5049 + Protein of unknown function DUF1934 + Phenol hydroxylase, C-terminal dimerisation domain + Protein Him1/Fmp52 + Cytochrome P450, E-class, group IV + Conserved hypothetical domain CHP03000, planctomycetes + UDP-glycosyltransferase, MGT + RNA-dependent RNA polymerase, eukaryotic-type + Membrane attack complex component/perforin (MACPF) domain + Domain of unknown function DUF1911 + Acyl homoserine lactone synthase + Expansin, cellulose-binding-like domain + Protein of unknown function DUF3039 + Restriction endonuclease, type II, BstXI + Paraneoplastic encephalomyelitis antigen + Lipocalin + Glutathione synthase + Zinc-binding loop region of homing endonuclease + Bacterial toxin 44 + Proteobacterial sortase system peptidoglycan-associated protein + Histidine acid phosphatase active site + Domain of unknown function DUF2135 + Glycine-zipper-containing OmpA-like membrane domain + Glycosyltransferase GT-D fold + C4-dicarboxylate anaerobic carrier + RNA polymerase sigma-I type + Nuclear transport factor 2 + Homocitrate synthase, fungi/archaea + Radical SAM peptide maturase, GG-Bacteroidales family + Protein of unknown function DUF3157 + PilX/PilW C-terminal domain + ABC transporter, urea utilisation-associated, substrate-binding protein + ATPase, type I secretion system, HlyB + Putative methanogenesis marker protein 11 + EAP30 + Thiopeptide-type bacteriocin biosynthesis domain + RNA polymerase sigma-70 factor, Planctomycetaceae + Flagellar FliJ, proteobacteria + Terpene synthase, conserved site + Quinohemoprotein amine dehydrogenase, alpha subunit domain IV + S-layer protein + Glycine oxidase ThiO + ERV/ALR sulfhydryl oxidase domain + Restriction endonuclease, type II, ScaI + Barrier- to-autointegration factor, BAF + Uncharacterised conserved protein UCP037205 + Trans-membrane regulatory protein ToxS + Toxin co-regulated pilus biosynthesis protein Q, C-terminal + Protein of unknown function DUF2778 + Uncharacterised conserved protein UCP028299 + E3 UFM1-protein ligase 1 + Protein of unknown function DUF2785 + His-Xaa-Ser system radical SAM maturase HxsB + Hopanoid biosynthesis associated radical SAM protein HpnH + Protein of unknown function DUF1040 + Antirepressor protein, C-terminal + Amicyanin/Pseudoazurin + Protein of unknown function DUF1906 + Integrating conjugative element protein PilL, PFGI-1 + Cellulose synthase + Domain of unknown function DUF2272 + CRISPR-associated protein, GSU0054 + Glycosyltransferase, GlcNAc + 2-methylcitrate dehydratase PrpD + Pyrimidine 5'-nucleotidase, eukaryotic + Nitrogen fixation protein NifM + Conserved hypothetical protein CHP02808 + Heavy metal sensor kinase + Transcriptional regulatory protein PcoR, heavy metal response + Protein of unknown function DUF3798 + YcnI-like + Campylobacter major outer membrane + Protein of unknown function DUF3150 + ParB-related, ThiF-related cassette, ThiF + Protein of unknown function DUF4783 + Rhomboid protease, N-terminal + Stealth protein CR3, conserved region 3 + Choice-of-anchor A domain + Zinc finger, CGNR + PcfJ-like protein + Protein of unknown function DUF3997 + Potassium channel, inwardly rectifying, Kir + Protein kinase G, tetratricopeptide repeat containing domain + Protocatechuate 4,5-dioxygenase, alpha subunit + Lysine-specific metallo-endopeptidase + Protein of unknown function DUF3541 + Fatty oxidation complex, alpha subunit FadJ + FAE1/Type III polyketide synthase-like protein + Mu DNA binding, I gamma subdomain + Protein of unknown function DUF3750 + Putative addiction module antidote + Phosphoenolpyruvate carboxylase, archaeal-type + 30S ribosomal protein Thx + Inositol monophosphatase, Lithium-sensitive + Nitrogen fixation negative regulator NifL + Glycoside hydrolase, family 85 + Type-F conjugative transfer system pilin assembly protein TrbC + Mercuric transport protein MerT + Luciferase-type oxidoreductase + Suppressor of fused-like domain + Protein of unknown function DUF1598 + Transposase, Tc1-like + ATP-grasp family + Ferric iron reductase, C-terminal + Seed maturation protein + 3(2),5 -bisphosphate nucleotidase HAL2 + Restriction endonuclease, type II, BglI + Protein of unknown function DUF2203 + Bacteriophage Mu, Gp25 + Ubiquitin + Acyl-CoA ligase (AMP-forming), exosortase system type 1 associated + Phosphogluconate dehydrogenase (decarboxylating) , C-terminal + LamB-type porin N-terminal domain + Protein of unknown function DUF1256 + Transmembrane protein 43 family + Pantothenate kinase + Laminin G domain + Ribonuclease HIII, N-terminal + Phage major tail protein, phi13 family + Cytochrome o ubiquinol oxidase, subunit I + Exosome complex component CSL4 + Pancreatic trypsin inhibitor Kunitz domain + Uncharacterised protein family UPF0478 + [FeFe] hydrogenase, group B1/B3 + Putative heme utilization radical SAM enzyme HutW + Tetracycline transcriptional regulator, TetR, C-terminal + Ribosomal protein L13e + Protein of unknown function DUF4262 + Pas factor saposin domain + Ribonucleoside reductase subunit beta, NrdF + Actin/actin-like conserved site + Integral membrane protein, YccS/YhfK + Protein of unknown function DUF896 + Minor capsid protein + Helix-turn-helix, conjugative transposon-like + Putative OmpA-OmpF-like porin family + Protein of unknown function DUF4839 + Domain of unknown function DUF5000 + Domain of unknown function DUF4116 + Cyclic di-GMP receptor, atypical PilZ domain + Protein of unknown function DUF1405 + Domain of unknown function DUF4453 + Bacteriophage lambda, GpH, tail tape measure, N-terminal + ESCRT-II complex, vps25 subunit + Cupin fold metalloprotein, WbuC family + Ubiquitin-activating enzyme E1, FCCH domain + DNA helicase, ATP-dependent, UvrD type + Protein of unknown function DUF3262 + AMP nucleosidase, putative + Peptidase M42, hydrolase + Diol dehydratase reactivase ATPase-like domain + Limonene-1,2-epoxide hydrolase + Leukocidin/porin + Novel toxin 16 + Mycoplasma virulence, signal domain + Phosphonatase-like hydrolase + Domain of unknown function DUF1735 + Integral membrane protein, YccS + Heme utilization carrier protein HutX-like + Protein of unknown function DUF4450 + Phosphotransferase system, N-acetylglucosamine-specific IIBC component + Carboxynorspermidine decarboxylase + Ribonuclease M5 + Integrating conjugative element protein, PFL4695 + IolE/MocC family + Quinoprotein relay system zinc metallohydrolase 2 + Macrophage migration inhibitory factor + Protein of unknown function DUF2214, membrane + Domain of unknown function DUF2399 + Photosystem II PsbY + HAD-superfamily hydrolase, LHPP/HDHD2 + Conserved hypothetical protein CHP00288 + Bacterial OB-fold + Peptidase G2, IMC autoproteolytic cleavage domain + Quinoprotein dehydrogenase-associated + Putative metal-binding protein + Ribosomal protein L18e, conserved site + Peptidase M8, leishmanolysin + Hexokinase, N-terminal + Bacterial purine repressor, N-terminal + Phage tail assembly chaperone TAC_10 + Potassium channel, inwardly rectifying, Kir, cytoplasmic + Bacteriophage lambda, GpS, holin + Protein of unknown function DUF2452 + Protein of unknown function DUF903 + Insecticidal toxin complex/plasmid virulence protein + Ribonuclease II + Carbohydrate binding X2 domain + Transglutaminase elicitor + Putative 5-3 exonuclease + Glycoside hydrolase, family 16, active site + HEAT repeat associated with sister chromatid cohesion protein + Benzoyl-CoA reductase, bzd-type, N subunit + Cyclohexa-1,5-dienecarbonyl-CoA hydratase + Zinc finger, double-stranded RNA binding + Uncharacterised protein family MTH865 + F420-binding domain, putative + Translational regulator Com + Protein of unknown function DUF2292 + Protein of unknown function DUF2290 + SH3b2-type SH3 domain + Endosialidase, N-terminal extension domain + SUN domain + Armadillo + Protein of unknown function DUF3872 + Condensin complex subunit 1, C-terminal + Protein of unknown function DUF3404 + Recombination, repair and ssDNA binding protein UvsY + Aspartate ammonia-lyase + ATP synthase YMF19-like, N-terminal + Zinicin-like metallopeptidase type 2 + TFIIH subunit TTDA/Tfb5 + Pyridoxamine 5'-phosphate oxidase, Alr4036 family, FMN-binding domain + Non-structural maintenance of chromosome element 4, C-terminal + Ragulator complex protein LAMTOR3 + Protein of unknown function DUF3703 + Sterile alpha motif domain + Helical bimodular sensor domain + Nitrate transport permease + Protein of unknown function DUF2018 + Conserved hypothetical protein CHP03808 + Protein of unknown function DUF2343 + 2-keto-3-deoxygluconate permease + Gp45 sliding clamp, C-terminal + Transcription regulator MAATS, C-terminal + Ataxin, AXH domain + Zinc finger, BED-type + Protein of unknown function DUF1407 + CD225/Dispanin family + Glycosyltransferase domain + YfaZ + Protein of unknown function DUF3025 + 3-alpha domain + Geranylgeranylglyceryl phosphate synthase, archaea + N-acetyltransferase ESCO, zinc-finger + Squalene epoxidase + HP0242-like domain + Phenylphosphate carboxylase, gamma subunit + GOLD domain + Uncharacterised domain, di-copper centre + Bacteriophage T7 tail fibre protein + Glycerol-3-phosphate cytidylyltransferase + P-type ATPase, subfamily IIB + Phenylacetate-CoA oxygenase/reductase, PaaK subunit + Peptidase M36, fungalysin + Lycopene cyclase, beta/epsilon + Bacterial toxin homologue of phage lysozyme, C-terminal + Thymidylate synthase, archaea + Protein of unknown function DUF4493 + Protein of unknown function DUF4494 + Spore germination YpeB + Sporulation protein YlmC/YmxH + CRISPR-associated protein Csy1 + Beta-lysine N-acetyltransferase + Chitinase, C-terminal + Phenylphosphate carboxylase, beta subunit + Bacteriophage phi-Lf, Orf112 + Protective antigen, heptamerisation domain + Hypothetical glycoside hydrolase 5 + Anthranilate synthase component I, TrpE-like, bacterial + GNAT N-acetyltransferase, putative + Uncharacterised conserved protein UCP006685 + CRISPR-associated protein DxTHG, conserved site + Protease inhibitor I35 (TIMP) + Homeobox protein, antennapedia type, conserved site + 3-hexulose-6-phosphate synthase + Patatin-related protein + Vacuolar protein sorting-associated, VPS28 + Domain of unknown function DUF550 + Protein of unknown function DUF1877 + DNA ligase D + Leucine-rich glioma-inactivated , EPTP repeat + Domain of unknown function DUF4149 + Domain of unknown function DUF4918 + Domain of unknown function DUF2479 + Protein of unknown function DUF2845 + Protein of unknown function DUF3194 + Glycosyl hydrolases family 9, Asp/Glu active sites + ABC transport system, 1-aminoethylphosphonate-binding protein, putative + Protein of unknown function DUF2227, metal-binding + Restriction system-associated AAA family ATPase + Neurotransmitter-gated ion-channel transmembrane domain + Citrate lyase ligase + Bacteriophage head completion protein GpL + Protein of unknown function DUF4907 + 2-oxo-hepta-4-ene-1,7-dioic acid hydratase + Lycopene cyclase + Uncharacterised protein family, RAQPRD + D-lactate dehydrogenase, C-terminal subdomain 1 + PQQ-dependent membrane bound dehydrogenase + DNA photolyase class 2, conserved site + DUF3686 + Putative 7-carboxy-7-deazaguanine synthase QueE, Proteobacteria + Phosphatase PHOSPHO-type + Inositol-tetrakisphosphate 1-kinase + Uncharacterised conserved protein UCP017998 + Protein of unknown function DUF3612 + Peptidase A22A, presenilin + Protein of unknown function DUF3325 + Protein of unknown function DUF4006 + Protein of unknown function DUF4003 + Protein of unknown function DUF3999 + Twin-arginine translocation signal, Cys-rich four helix bundle protein + Protein of unknown function DUF5076 + Cupin 1 + Bacteriophage holin HP1 family + Ferredoxin-dependent bilin reductase + Uncharacterised protein MJ0570 + Replicative helicase inhibitor G39P, N-terminal + Capsular polysaccharide synthesis + Protein of unknown function DUF4304 + Hexon coat protein, subdomain 4 + Pyridoxal-dependent decarboxylase, exosortase system type 1 associated + Domain of unknown function DUF4424 + Subtilase, N-terminal + Bacteriophage P22 tailspike, N-terminal + Beta-lactamase-inhibitor protein BLIP + Protein of unknown function DUF1176 + Protein of unknown function DUF1651 + Carbohydrate binding module family 20 + FAD-dependent oxidoreductase, HpnW + Chorismate mutase, archaeal + 2-succinylbenzoate--CoA ligase + YcbB domain + Endoglucanase Z, cellulose-binding domain + P-type ATPase, subfamily IIA, SERCA-type + Domain of unknown function DUF2185 + Legume lectin, beta chain, Mn/Ca-binding site + LGFP + Domain of unknown function DUF5109 + Succinylglutamate desuccinylase + Isopropylmalate/isohomocitrate dehydrogenase + Surface antigen domain + ThiJ/PfpI family-like + Enolase-phosphatase E1 + Phosphoribosyl transferase + Nitrogenase MoFe cofactor biosynthesis protein NifE + Protein of unknown function DUF4358 + Cobalamin (vitamin B12) biosynthesis CobG-like + ZU5 domain + Flavin amine oxidase + Protein of unknown function DUF1090 + Specific amino acids and opine-binding periplasmic protein, ABC transporter + Protein of unknown function DUF4747 + Filamentous haemagglutinin family outer membrane protein, domain of unknown function DUF3739 + Putative flagellar system-associated repeat + Baseplate wedge protein gp53, bacteriophage T4 + Brain protein I3 + Phytoene dehydrogenase, bacterial-type, conserved site + DP-EP family + Domain of unknown function DUF5123 + Chromophore lyase CpcS/CpeS + Nitrogenase-associated protein + Bacteriophage lambda, GpZ, minor tail + Antitoxin RnlB/LsoB + Phage late-transcription coactivator + Protein of unknown function DUF4863 + Phage-associated protein, BcepMu gp16 family + Conjugative transposon, TraN + Copper transporter MctB + Carboxypeptidase, activation peptide + Ubiquitin-conjugating enzyme, E2, family E + InsA N-terminal domain + Flagellin, H7-serospecific domain + Uncharacterised protein family AF2234 + Protein of unknown function DUF1802 + Bacteriophage D3112, Orf24 + Hydroxypyruvate isomerase + Integrating conjugative element protein PFL4702 + Cellulose biosynthesis protein BcsS + Staygreen protein + SAM-dependent methyltransferase, NodS-related + SAM dependent carboxyl methyltransferase + Exonuclease V + Protein of unknown function DUF2666 + Chromosome partition protein MukF, C-terminal domain + Chromosome partition protein MukF, middle domain + Chemotaxis signal transduction system protein F + Transglycosylase-like + Pur operon repressor + Alpha 1,4-glycosyltransferase domain + Mitochondrial substrate/solute carrier + DNA sulphur modification system-associated protein 4 + Nitrogen fixation protein NifX + Photosystem II reaction centre protein Ycf12 + Domain of unknown function DUF4993 + ATPase, A1 complex, beta subunit + Domain of unknown function DUF4082 + 2-hydroxycarboxylate transporter + F420-dependent oxidoreductase-predicted, CPS4043 + Protein of unknown function DUF4235 + Putative aminophosphonate oxidoreductase + YkuI, C-terminal + Sporulation stage II, protein P + Stage V sporulation AD + Uncharacterised conserved protein UCP018814 + Peptidase S1C, DegS + Virulence factor YopE uncharacterised domain + Zn(II)-responsive transcriptional regulator + Uncharacterised protein family, VP2110 + Acid phosphatase, class A, bacterial, conserved site + Uncharacterised protein family UPF0184 + Cysteine desulphurase, catalytic subunit, CsdA + Sporulation protein YabP/YqfC + Protein of unknown function DUF3346 + O-phosphoseryl-tRNA(Sec) selenium transferase + Domain of unknown function DUF4469 with IG-like fold + Conserved hypothetical protein CHP03577, EF0830/AHA3911 + YolD-like protein + CpcD-like domain + Nudix hydrolase 6-like + Poxvirus A32 + Protein of unknown function DUF3225 + PELOTA RNA-binding domain + Chromophore lyase CpcT/CpeT + Protein of unknown function DUF2000 + SynChlorMet cassette radical SAM/SPASM protein ScmE + Protein of unknown function DUF2243, membrane + Lacto-N-biose phosphorylase-like, N-terminal TIM barrel domain + MatP, N-terminal + WavE lipopolysaccharide synthesis + Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 + CRISPR-associated protein, TM1812 + Phosphotransferase system, beta-glucoside-specific IIABC component + Avidin/streptavidin + Glucitol operon activator + Amino acid permease, conserved site + D-aminopeptidase/lipoprotein domain + Protein of unknown function DUF3400 + Protein of unknown function DUF1861 + Conjugative coupling factor TraG/TraD + Aspartate-alanine antiporter + Conserved hypothetical protein CHP03883, F420 biosynthesis associated + Protein of unknown function DUF2498 + Diol dehydratase-reactivating factor, alpha subunit, swiveling domain + Restriction endonuclease, type II, BpuJI, N-terminal + GTP-sensing helix-turn-helix, CodY, C-terminal + Trp repressor, bacterial + Protein of unknown function DUF2857 + SH2 domain + LRV FeS4 cluster + YozE SAM-like domain + Alkaline proteinase inhibitor/ Outer membrane lipoprotein Omp19 + mRNA interferase toxin YafO + 4Fe-4S binding protein + Xylella phage Xfas53, Orf42 + Minor capsid protein, bacteriophage + Conjugal transfer, TrbL + ParB protein family, C-terminal + Urea carboxylase + Amidohydrolase, AtzE type + Phosphoinositide phospholipase C, Ca2+-dependent + YopD-like + Domain of unknown function DUF1882 + Protein of unknown function DUF3431 + Glycoside hydrolase, family 25, active site + Protein of unknown function DUF2861 + Bacteriophage T4, Y12G + Glycoside hydrolase family 11/12 + Outer membrane lipoprotein RcsF + 2,3-diaminopropionate biosynthesis protein SbnB + Lantibiotic dehydratase, C-terminal + Protein of unknown function DUF1345 + Protein translocase subunit SecA, Actinobacteria-type + EGF-like, conserved site + Protein of unknown function DUF1838 + Luciferase-like, F420-dependent oxidoreductase, MSMEG2256, predicted + Domain of unknown function DUF4297 + Rhamnosyltransferase + Domain of unknown function DUF3825 + Sama2622-like domain + Protein of unknown function DUF4410 + Ribosomal RNA processing protein 8 + Protein of unknown function DUF5330 + DNA polymerase III, alpha subunit, Gram-positive type + Alpha-1,6-glucosidases, pullulanase-type + Citrate transporter + Photosystem I PsaL, reaction centre subunit XI + Aerolysin/Pertussis toxin APT + Muconate/chloromuconate cycloisomerase + YIEGIA protein + Protein of unknown function DUF5052 + 4-oxalocrotonate decarboxylase + GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal + Immunity protein 27 + Immunity protein 10 + Low calcium response V antigen + Urea carboxylase-associated protein 1 + Dehydratase YjhG/YagF + Protein of unknown function DUF1413 + Protein of unknown function DUF1420 + Uncharacterised protein family UPF0167 + Protein of unknown function DUF5329 + Autonomous glycyl radical cofactor GrcA + Integrating conjugative element protein, PFL4709 + Sigma factor-binding protein Crl + Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase, eukaryotic + Dihydrodipicolinate reductase, plant-type + Iron/zinc purple acid phosphatase-like C-terminal domain + Parvovirus non-structural protein 1, helicase domain + Protein of unknown function DUF1707 + PA-IL-like + Pilus assembly protein, C-terminal domain + XACb0070, ribbon-helix-helix domain + Formyl-CoA:oxalate CoA-transferase + Signal transduction histidine kinase, TMAO sensor TorS + TMAO reductase system, periplasmic protein TorT + TIP49, C-terminal + Poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD + Protein of unknown function DUF4310 + Nif11-like leader peptide + Sortase system, histidine kinase + Ubiquitin conserved site + Secretion system effector C, SseC-like + Nitric oxide synthase, N-terminal + Immunity protein 22 + Microcompartment protein PduB + ATPase, RavA, C-terminal + Ornithine decarboxylase, N-terminal domain + Alpha-maltose-1-phosphate synthase + Pacifastin domain + DNA polymerase lambda, fingers domain + Protein of unknown function DUF2810 + Protein of unknown function with TPD sequence-motif + Protein of unknown function DUF1980 + Domain of unknown function DUF1983 + Flavivirus NS3, petidase S7 + Glycosyltransferase family 1, Daro2409 family + 2-component histidine kinase, sensor domain + Conserved hypothetical protein CHP03905 + Protein of unknown function DUF3792, transmembrane + DNA phosphorothioation-dependent restriction protein DptF + Repair of iron centres family + Purine-rich element binding protein family + Conserved hypothetical protein CHP03016, PEP-CTERM + Type II secretion system (T2SS) pilotin, S protein + Quinohemoprotein amine dehydrogenase, alpha subunit, haem binding domain + Stage III sporulation protein AH-like + Protein of unknown function DUF4928 + YXWGXW repeat + YqjK-like protein + Protein of unknown function DUF2581 + NAD(P)H-quinone oxidoreductase subunit M + Phosphotransferase system, mannitol-specific enzyme IIC + Fumarate reductase, flavoprotein subunit + SCIFF radical SAM maturase + Squalene-associated FAD-dependent desaturase + Rad9/Ddc1 + Viral late gene transcription factor 3 , zinc ribbon + Protein of unknown function DUF452 + Carbohydrate binding module family 25 + Serine proteases, V8 family, histidine active site + Amino acid antiporter + Granulocyte-macrophage colony-stimulating factor + MerE + TonB-system energizer ExbB type-2 + CRISPR-associated protein, Cas6-related + tRNase Z endonuclease + Peptidase U49, Lit peptidase + Peptidase M66 domain + Alkylmercury lyase, helix-turn-helix domain + Phosphotransferase system, sorbose subfamily IIB component, subgroup + B melanoma antigen + Two-component sensor protein CpxA, periplasmic domain + Protein of unknown function DUF3147 + Exosortase 1 + Lipopolysaccharide heptosyltransferase III, putative + Domain of unknown function DUF4975 + Protein of unknown function DUF2695 + Low affinity iron permease, Fet4 + Rhamnogalacturonan lyase, domain II + Type III secretion system effector delivery regulator TyeA + Phosphotransferase system, EIIC component, type 3 + Domain of unknown function DUF4351 + Protein of unknown function DUF3995 + Bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase + Aldose 1-epimerase, bacterial + Protein of unknown function DUF3823 + Diacylglycerol kinase, accessory domain + LuxT regulator, C-terminal domain + MukB, hinge domain + Glycerol-3-phosphate transporter + Putative toxin of bacterial toxin-antitoxin pair + Protein of unknown function DUF2817 + REDY-like protein HapK + Catechol 1,2-dioxygenase, proteobacteria + Putative phosphonoacetaldehyde dehydrogenase + Type III secretion system effector delivery regulator TyeA-related + Protein of unknown function DUF5368 + NrfD + Cytochrome c nitrite reductase, Fe-S protein + Cytochrome c nitrite reductase, pentahaem subunit + Bacteriophage T4, Gp16, DNA-packaging + Ribosomal protein L34e, conserved site + Putative methyltransferase, LIC12133 family + Protein of unknown function DUF1344 + snRNA-activating protein complex, subunit 3 + Ergosterol biosynthesis ERG4/ERG24 + TMP repeat + Glycosyltransferase family 52 + Protein of unknown function DUF3748 + Protein of unknown function DUF3319 + Coronavirus Orf3 + Novel toxin 21 + Type III secretion sytem,YscO + CRISPR-associated protein Csx17, subtype Dpsyc + Lactobacillus prophage Lj928, Orf309 + Bacterial phospholipase C, C-terminal domain + Aspartic peptidase, DDI1-type + Conserved hypothetical protein CHP02304, F390 synthetase-related + Photosystem II cytochrome b559, alpha subunit, lumenal region + Sulphate ABC transporter, permease protein CysW + Phage infection protein, YhgE, N-terminal + Phage infection protein, YhgE, C-terminal + Conserved hypothetical protein CHP03067, planctomycetes + Oil body-associated protein-like + Bacteriophage clamp loader A subunit + CRISPR-associated protein, Csx11 + Siderophore ferric iron reductase, AHA1954 family + Bacteriocin, class IIb, lactobin A/cerein 7B family + Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ + Conserved hypothetical protein CHP02270 + Benzoyl-CoA reductase, subunit C + Benzoyl-CoA reductase, subunit D + Pectinacetylesterase/NOTUM + Plasmid regulator, Sulfolobaceae + Protein of unknown function DUF1878 + Allantoicase + Thiamine ABC transporter, permease protein + Formate acetyltransferase + Vitellinogen, beta-sheet N-terminal + ESCRT-II complex, Vps25 subunit, N-terminal winged helix + Protein of unknown function DUF5458 + CRISPR-associated RAMP TM1809 + Sporulation stage II, protein D firmicutes + Sucrose-6-phosphate hydrolase + Protein of unknown function DUF347 + Stage III sporulation protein AB + Sporulation protein YtxC + Novel toxin 15 + Calcium/proton exchanger CAX + Protein of unknown function DUF3577 + 3H domain + L27 domain + Mycoplasma P48 major surface lipoprotein + Putative bacterial toxin ydaT + F420-dependent oxidoreductase-predicted, Rv3520c + Pseudoazurin + Vibrio phage CTX, RstB + Peptidase U57, YabG + HARP domain + Ribonucleotide reductase Class Ib, NrdI + DNA polymerase III subunit tau, DnaB-binding domain IV + Protein of unknown function DUF1629 + Glycoside hydrolase, family 35, conserved site + Hen1, N-terminal + Hemagglutinin repeat + Protein of unknown function DUF4311 + Sporulation stage II, protein R + Benzylsuccinate synthase gamma subunit + Protein of unknown function DUF3487 + Potassium channel, voltage dependent, KCNQ + S-layer protein, N-terminal + KorB, C-terminal + Sortase system response regulator + Protein of unknown function DUF4241 + Glycoside hydrolase family 47 + Type III secretion system YscG + Protein of unknown function DUF3348 + Protein of unknown function DUF1422 + ABC-2 type transporter, NodJ + Restriction endonuclease, type II, Cfr10I/Bse634I + Domain of unknown function DUF1543 + Protein of unknown function DUF3304 + Benzoyl-CoA reductase, subunit B + Allene oxide cyclase/dirigent protein + Benzoyl-CoA reductase, subunit A + CAP Gly-rich domain + Planctomycete extracellular + Allantoicase domain + Plant ascorbate peroxidase + HprK-related kinase B + Domain of unknown function DUF4996 + Glycosyl transferase, family 13 + Uncharacterised protein family MJ0414 + DNA helicase (DNA repair), Rad3 type + Chromosome partition protein MukF, winged-helix domain + Alkylbase DNA glycosidase, conserved site + His-Xaa-Ser system protein HxsD + Chemotaxis methyl-accepting receptor, methyl-accepting site + Borrelia P83100 + Protein of unknown function DUF4893 + Glycerol-3-phosphate dehydrogenase, GlpB subunit + Uncharacterised protein family UPF0253 + Protein of unknown function DUF4134 + Domain of unknown function DUF3794 + Cysteine-rich secretory protein, allergen V5/Tpx-1-related + Transthyretin-like + Glycosyltransferase family 92 + Domain of unknown function DUF4224 + Toxin endonuclease, YhaV + Conjugative transposon, TraM + Domain of unknown function DUF3864 + Cystatin domain + Protein of unknown function DUF2933 + Dictyostelium (slime mold) repeat + Domain of unknown function DUF2433 + Type-IV b secretion system, inner-membrane complex component + Glycoside hydrolase, family 14 + S-adenosylmethionine decarboxylase + DNA-directed RNA polymerase subunit delta + Bacteriophage-associated immunity protein + MSEP-CTERM protein + Exosortase K + Glutathione synthase, alpha-helical, eukaryotic + SynChlorMet cassette protein ScmD + Glycolipid exporter Gap/Sap + Kelch repeat type 2 + Integral membrane protein YjbE + Protein of unknown function DUF4239 + MukB, N-terminal domain + F420-dehydrogenase, subunit FpoO + Calponin homology domain + Ubiquinone biosynthesis protein Coq4 + Conserved hypothetical protein CHP03788 + Parallel beta-helix repeat-containing domain + Cytochrome c-550 domain + Domain of unknown function DUF1833 + Protein of unknown function DUF1836 + Outer membrane protein Iml2/Tetratricopeptide repeat protein 39 + Protein of unknown function DUF4056 + Acid phosphatase, class A, bacterial + Clathrin, heavy chain, linker + Protein of unknown function DUF2259, secreted + Potassium-transporting ATPase A chain + Nitrate/trimethylamine N-oxide reductase NapE/TorE + Uncharacterised conserved protein UCP019883, membrane + Staphostatin A/B + Adenylylsulphate reductase, alpha subunit + Beta-1,4-galactosyltransferase + Telomere resolvase ResT + Protein of unknown function DUF4303 + Acidianus two-tailed virus, Orf117 + Domain of unknown function DUF4064 + Sulphate transport system permease protein 1 + Cytochrome f large domain + Type II secretion system protein N, conserved site + Mannan-binding protein + Protein of unknown function DUF5350 + Lipoprotein leucine-zipper + Cellulose biosynthesis protein BcsG + Cellulose biosynthesis protein BcsE + CshA-type fibril repeat + Protein of unknown function DUF1364 + Proteinase inhibitor I3, Kunitz legume + Protein-arginine deiminase, C-terminal + Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A + Transcription termination factor, mitochondrial/chloroplastic + Quinohemoprotein amine dehydrogenase, gamma subunit, structural domain + Domain of unknown function DUF2382 + Hemopexin, conserved site + Photosystem II protein D1 + Pa2218-like domain + Acetoin utilization protein AcuC + Protein of unknown function DUF3392 + Cysteine dioxygenase type I + Protein of unknown function DUF3389 + Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB + Protein of unknown function DUF4836 + Protein of unknown function DUF1481 + CRIB domain + AntA/AntB antirepressor + RNA cap guanine-N2 methyltransferase + Putative outer membrane protein + Ubiquinol cytochrome reductase, transmembrane domain + Cyd operon protein YbgE + Proteasome component (PCI) domain + Ribonucleotide reductase, class 1b, subunit NrdE + Thiamine ABC transporter, ATP-binding protein ThiQ + Sulphate/thiosulphate-binding site + Phosphoribosylformylglycinamidine synthase, FGAM + CRISPR-associated protein, Csn2-type + Pilus biogenesis CpaD + Protein of unknown function DUF3199, YqbG + Replication protein A, C-terminal + mRNA (guanine-N(7))-methyltransferase domain + Uncharacterised protein family UPF0180 + Uncharacterised protein family UPF0181 + Protein of unknown function DUF2608 + ESPR domain + Trehalose operon repressor + Cecropin + Uncharacterised conserved protein UCP021328 + Phosphoserine phosphatase RsbU, N-terminal + Ubiquitin specific protease, conserved site + Deaminases, BURPS668_1122 family + Uncharacterised protein family CsiD + Diol dehydratase-reactivating factor alpha subunit + Peptidase S1A, streptogrisin + GGGtGRT protein + Mitochondrial degradasome RNA helicase subunit, C-terminal domain + Protein of unknown function DUF3069 + TonB system transport protein ExbD type-2 + Protein of unknown function DUF3094 + Glycosyl hydrolase family 100 + 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT2 + ABC transporter, membrane fusion protein, DevB type + Trimethylamine N-oxide reductase system, TorE + Phage shock protein, PspG + Sucrose phosphorylase GftA + Protein of unknown function DUF2004 + Gamma interferon inducible lysosomal thiol reductase GILT + Protein with unknown function UPF0154 + Peptide-N-glycosidase F, C-terminal + Hedgehog, N-terminal signalling domain + Uncharacterised conserved protein UCP021940 + Holin, r1t-type + Phytochelatin synthase + Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain + Bacterial Ig-related + U box domain + Vibrio phage Vf33, Vpf117 + Restriction endonuclease, type II, FokI, N-terminal + Domain of unknown function DUF4031 + Chalcone isomerase, orthogonal bundle domain + Citrate synthase, eukaryotic-type + Arsenite oxidase, large subunit + Hopanoid-associated sugar epimerase + RNA-binding S4-related,YaaA + Clostridial hydrophobic repeat + YcaO domain protein + Photosystem II cytochrome b559, alpha subunit + Lyase, N-terminal + Ribosome recycling factor. bacterial + Protein of unknown function DUF2380 + Protein of unknown function DUF2115 + Carbonic anhydrase, cadmium-binding + Knottin, scorpion toxin-like + Protein of unknown function DUF2280 + D-erythrose-4-phosphate dehydrogenase + Portal protein, SPP1-type + DREV methyltransferase + Dimethylsulphoxide reductase, chain B + Protein of unknown function DUF4924 + Protein of unknown function DUF1104 + LuxQ, periplasmic + Restriction endonuclease, type II, FokI, catalytic domain + His-Xaa-Ser system radical SAM maturase HxsC + Precorrin 3B synthase CobZ + Citrate utilization protein B + Holliday junction resolvase, A22 + Lipid A biosynthesis myristoyltransferase + Protein of unknown function DUF3565 + Beta-carotene 15,15'-monooxygenase, Brp/Blh family + Putative sugar phosphate phospholyase (cyclising) + Phosphonoacetate hydrolase + Protein of unknown function DUF1492 + Ferredoxin [2Fe-2S], plant + Arsenical-resistance operon trans-acting repressor ArsD + Photosynthetic complex assembly protein 2, putative + Heme utilization protein with pyridoxamine 5'-phosphate domain + Putative Na+/H+ antiporter + Histone H1-like nucleoprotein HC2 + Universal stress protein B + Mig-14 + Defensin propeptide + Conserved hypothetical protein CHP00743 + Predicted archaeal flagellar protein C + Putative motility protein + Peptidase S59, nucleoporin + Bacterial shufflon protein, N-terminal + Domain of unknown function DUF3863 + Formate-dependent cytochrome c nitrite reductase, c552 subunit + Glutaredoxin-2 + Domain of unknown function DUF4829 + Protein of unknown function DUF2278 + Protein of unknown function DUF3624 + Alpha-L-arabinofuranosidase B, arabinose-binding domain + Domain of unknown function DUF2231, transmembrane + T4-type lysozyme + Thiamine pyrophosphokinase C-terminal + Flagellar export ATPase FliI, clade 2 + Alpha-N-acetylglucosaminidase, N-terminal + Putative carbamoyltransferase YgeW + Alternate ATP synthase, F0 complex, subunit b + Ethanolamine/propanediol utilisation protein, EutP/PduV + ABC transporter, methionine import, ATP-binding protein MetN, proteobacteria + Histidine decarboxylase proenzyme + Uncharacterised protein family, nitrogen regulatory protein PII-related + Uncharacterised protein family Atu4866 + ATPase, type III secretion system, H+-transporting + Type III secretion system apparatus protein YscQ/HrcQ/SpaO + Homospermidine synthase-like, domain + Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type + Enterochelin esterase, N-terminal + Protein of unknown function DUF4004 + Type-2 restriction enzyme NlaIV + Protein of unknown function DUF4856 + RecG, N-terminal antiparallel four helix bundle + Tellurite resistance protein TehA/malic acid transport protein + Flagellar protein FlhE + Zinc finger, RING-type, conserved site + Gonadotropin-releasing hormone + Lantibiotic biosynthesis protein, dehydration domain + Immunoglobulin I-set + Lipoprotein-releasing system transmembrane protein LolC/E, gammaproteobacteria type + Exosortase 1 system-associated amidotransferase 1 + GNAT-acetyltransferase + Hydrolase, ortholog 1, exosortase system type 1 associated + Sulphur globule protein + Sigma factor regulator C-terminal domain + Major capsid protein, N-terminal + Recombination enhancement, RecA-dependent nuclease + Conjugal transfer/type IV secretion protein DotA/TraY + Thiazole/oxazole-forming peptide maturase, SagD family component + Stage III sporulation protein AC/AD family + Protein KTI12/L-seryl-tRNA(Sec) kinase + Protein of unknown function DUF1646 + Fimbrial-type adhesion domain + Domain of unknown function DUF3376 + DNA polymerase III polC-like, N-terminal domain II + PIK-related kinase, FAT + Bicarbonate transporter, C-terminal + Glycogen debranching enzyme, glucanotransferase domain + Cellulose synthase, subunit B + SpoVA + Protein of unknown function DUF2171 + Protein of unknown function DUF3309 + Restriction endonuclease, type II, HincII + DDRGK domain containing protein + Domain of unknown function DUF4253 + Muconolactone delta-isomerase + Glycoside hydrolase, family 68 + Ribosome-inactivating protein, subdomain 1 + Leucine-rich repeat-containing N-terminal, plant-type + Mercuric transport protein periplasmic component + Pilus assembly protein, E-set like domain + Azurin + Protein of unknown function DUF4855 + Allergen V5/Tpx-1-related, conserved site + Domain of unknown function DUF3597 + Extracellular endo-alpha-(1->5)-L-arabinanase, C-terminal + Putative component of 'biosynthetic module' + Protein of unknown function DUF4343 + LCCL domain + Beta-ketoadipate transcriptional regulator, PcaR/PcaU/PobR + Immunoglobulin/major histocompatibility complex, conserved site + Protein of unknown function DUF2895 + Tn7 transposition regulator TnsC + Vibrio phage VSK, Orf152 + Mercury ion transport, MerF + Peptidase M12A + Cytidine deaminase, homodimeric + Putative bacteriocin export ABC transporter, lactococcin 972 group + Domain of unknown function DUF5071 + Cysteine-rich CPCC domain + Domain of unknown function DUF5106 + Gammaproteobacterial periplasmic sensor domain GAPES4 + Pyridoxal phosphate-dependent enzyme, SelA-like + Protein of unknown function DUF496 + Guanine-specific ribonuclease N1/T1/U2 + Ribophorin I + Amine dehydrogenase heavy chain + Pyrophosphate-dependent phosphofructokinase PfpB + Protein of unknown function DUF4860 + Chorismate mutase, Gram-positive + Streptococcal non-M secreted SibA + Bacteriocin biosynthesis, cyclodehydratase domain + Integrating conjugative element protein, PFL4693 + TATA box binding protein associated factor (TAF) + Adhesin operon regulatory protein + Protein of unknown function DUF3189 + Protein of unknown function DUF3188 + Protein of unknown function DUF2508 + Glycoprotein E central domain, subdomain 2 + Glycoside hydrolase, family 8, conserved site + NAD:arginine ADP-ribosyltransferase, ART + Protein of unknown function DUF4862 + Uncharacterised conserved protein UCP014484, transmembrane + Flavivirus/Alphavirus glycoprotein, immunoglobulin-like domain + Selenium-dependent xanthine dehydrogenase + ATP synthase subunit beta, bacterial and archaeal + Uncharacterised protein family AF1718 + Glycosyl hydrolases family 10, active site + Stealth protein CR4, conserved region 4 + Photosystem II cytochrome b559, beta subunit + Protein kinase C-like, phorbol ester/diacylglycerol-binding domain + Conjugal transfer, TraD, alpha-type + Beta-1,4-N-acetylgalactosaminyltransferase + Domain of unknown function DUF5006 + DNA topoisomerase IV subunit A, Gram-positive + DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes + Baseplate tail-tube protein gp48, T4-like virus + HisA/HisF-like protein + Essential protein Yae1, N-terminal + Ubiquitin-conjugating enzyme E2-binding protein + Long-chain fatty aldehyde decarbonylase + Benzoate 1,2-dioxygenase, small subunit + Bacterial EndoU nuclease + STAT transcription factor, DNA-binding, subdomain + Small acid-soluble spore protein, SspH + Uncharacterised protein family Ycf36 + Phenolic acid decarboxylase, bacterial + YmaF + DotD protein + Sporulation delaying protein SdpA + Ubiquitin system component Cue + Protein of unknown function DUF930 + Domain of unknown function DUF4937 + Cytochrome b6/f complex, subunit 5 + Apoptosis inhibitory 5 + HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase + Protein of unknown function DUF3455 + PAM68-like + C-type cytochrome, methanol metabolism-related + Protein AC76, baculovirus + Protein-arginine deiminase (PAD), central domain + CRISPR-associated protein Csm6 + Vacuolating cytotoxin + Protein phosphatase inhibitor 2 (IPP-2) + Decahaem cytochrome, c-type, OmcA/MtrC + Hg(II)-responsive transcriptional regulator + Zinc finger, MYND-type + Cell wall/choline-binding repeat + Arsenical pump-driving ATPase + MHC class I-like antigen recognition-like + Protein of unknown function DUF5335 + ATP synthase alpha chain, archaea + Protein of unknown function DUF2024 + Histone acetyl transferase HAT1 N-terminal + DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site + Domain of unknown function DUF5126 + Translation Initiation factor eIF- 4e + CxxC-20-CxxC protein + Protein of unknown function DUF4385 + Domain of unknown function DUF3875 + MAD homology, MH1 + CSN8/PSMD8/EIF3K + Transposase (putative), N-terminal + Probable zinc-ribbon domain, plant + Di-heme enzyme, MXAN0977 + Protein of unknown function DUF1380 + Haemolysin XhlA + HSR domain + Protein of unknown function DUF3483 + Sporulation protein YqfC + Molybdate-anion transporter + Herpesvirus UL92 + Type III secretion, needle-protein-like + Cobalt transport protein CbiN + Protein of unknown function DUF4312 + XisI protein + Protein of unknown function DUF1830 + Putrescine transporter PotE + DNA phosphorothioation-associated DGQHR protein 1 + Peptidase S28 + Adenovirus large t-antigen, E1B 55kDa protein + Magnesium chelatase, ATPase subunit D + Cytochrome b6/f complex, subunit IV + Spore coat protein CotJA + Protein of unknown function DUF2917 + Vacuolar protein sorting protein 36, GLUE domain + Quinoprotein relay system zinc metallohydrolase 1 + Protein of unknown function DUF2242 + 26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 + Six-cysteine peptide SCIFF + Cullin, conserved site + Mitochondrial ribosomal protein MRP51, fungi + Putative pyrophosphorylase ModD + Carboxysome shell protein + Bacteriophage RNA-type, capsid + Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2 + FeS assembly scaffold SufA + PTS system glucose-specific IIBC component + Domain of unknown function DUF2345, Vgr C-terminal + Chloroplast protein import component Tic20 + Cytochrome C oxidase, subunit VIIB, domain + Conserved hypothetical protein CHP03829, YokU + Protein of unknown function DUF810 + Magnesium transporter NIPA + Protein of unknown function DUF2505 + Acyl transferase, LuxD + Hemingway/KIAA1430 + Molybdenum-binding protein ModE, N-terminal + Protein of unknown function DUF1816 + Protein of unknown function DUF1818 + HMG-I/HMG-Y, DNA-binding, conserved site + Protein of unknown function DUF5041 + Quinohemoprotein amine dehydrogenase, gamma subunit maturation protein + Quinohemoprotein amine dehydrogenase, alpha subunit + Manganese catalase, domain 2 + 7TM GPCR, serpentine receptor class t (Srt) + 7TM GPCR, serpentine chemoreceptor class i (Sri) + VWFC domain + SANT/Myb domain + Protein of unknown function DUF273 + Type III secretion system, secretion protein E + Type III secretion system, YscI/HrpB + Type III secretion system chaperone SycN + Type III secretion system YscX + Protein of unknown function DUF4221 + Phosphotransferase system, alpha-glucoside-specific IIBC component + Fatty acyl-CoA reductase, C-terminal + Protein of unknown function DUF2944 + tRNA methyltransferase TrmK + Amino acid transporter, transmembrane domain + Uncharacterised domain AF0941 + Protein import receptor MAS20 + Cadmium resistance transporter + Bacteriophage M13, G5P, DNA-binding + Sensitivity To Red Light Reduced-like, SRR1 + Glycoside hydrolase, family 33, N-terminal + Protein of unknown function DUF986 + Dim1 family + Ferric iron reductase + Protein of unknown function DUF1870 + Af2093, N-terminal + Minor capsid protein, putative + PetM of cytochrome b6/f complex subunit 7 + Dicarboxylate-CoA ligase PimA + p53, tetramerisation domain + Zinc finger, ZZ-type + Peptidase M12B, propeptide + Septation ring formation regulator EzrA + Whirly transcription factor + Predicted [NiFe]-hydrogenase-3-type complex Eha, membrane protein EhaE + Predicted [NiFe]-hydrogenase-3-type complex Eha, membrane protein EhaF + NMB0513-like domain + X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain + MOB kinase activator family + Phosphomannomutase + Hemolytic lectin CEL-III, C-terminal domain + ATP synthase, F0 complex, subunit B/MI25 + Phage-associated protein HI1409 + Insertion element IS1 protein InsA, helix-turn-helix domain + Protein of unknown function DUF346 + Signal recognition particle receptor, beta subunit + Protein of unknown function DUF4362 + Thrombospondin type-1 (TSP1) repeat + BphX-like + Flagellar assembly regulator FliX, class II + UDP-glycosyltransferase family, conserved site + Porin family, mycobacterial-type + Type III secretion protein HrcV + Type III secretion protein SpaR/YscT + Type III secretion protein HrpO + VDE lipocalin domain + Phosphomevalonate kinase + Integrin alpha chain, C-terminal cytoplasmic region, conserved site + Rhombotail lipoprotein + Phosphomutase MSMEG4193, putative + Protein of unknown function DUF3060 + Stage V sporulation protein AE + Type III secretion system lipoprotein HrcJ/YscJ + Benzoate 1,2-dioxygenase, large subunit + CRISPR-associated protein Cas1, cyanobacteria-type + Conserved hypothetical protein CHP04042, MSMEG0570 + Conserved hypothetical protein CHP04044, MSMEG0572 + Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted + Spc7 kinetochore protein domain + Domain of unknown function DUF5057 + Protein of unknown function DUF5054 + Rotavirus NSP2, N-terminal + ParB-related, ThiF-related cassette, ParB + HAD-superfamily hydrolase, subfamily IB, PSPase-like, archaeal + Protein of unknown function DUF2993 + Trehalose-6-phosphate hydrolase + Malto-oligosyltrehalose trehalohydrolase + Maltooligosyl trehalose synthase + Type III secretion system, low calcium response, chaperone LcrH/SycD + Domain of unknown function DUF1725 + Domain of unknown function DUF4394 + Parvovirus coat protein VP2 + Transcription regulator PadR, acidobacterial-type + Tropomyosin + Zinc finger, FLYWCH-type + Protein of unknown function DUF2634 + Yop protein translocation protein D, periplasmic domain + Type VI secretion system (T6SS), amidase immunity protein + Membrane attack complex component/perforin domain, conserved site + MbeD/MobD-like + Domain of unknown function DUF1990 + Tyrosine 2,3-aminomutase, putative + YecR-like lipoprotein + CRAL-TRIO lipid binding domain + Magnesium chelatase, subunit H, N-terminal + Jacalin-like lectin domain + GTP cyclohydrolase N-terminal + Protein of unknown function DUF3086 + Protein of unknown function DUF3088 + Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 + CbxX/CfqX, monofunctional + Type III secretion system chaperone YscB + Heterokaryon incompatibility + Conserved hypothetical protein CHP04066, peptide maturation system + Protein of unknown function DUF4355 + Protein of unknown function DUF4823 + Glucosylglycerol-phospate 3-phosphatase + 3'5'-cyclic nucleotide phosphodiesterase, conserved site + Vacuolar protein sorting-associate protein Vta1/Callose synthase, N-terminal domain + Type III secretion system, secretion protein K + Retrovirus capsid, C-terminal + Malonate transporter MadL subunit + RNA polymerase Rpb1, domain 6 + Conserved hypothetical protein CHP03792 + BCP1 family + Porin, Neisseria sp. type + CAP, conserved site, N-terminal + Cyanobacterial aminoacyl-tRNA synthetase, CAAD domain + Domain of unknown function DUF4334 + Arylesterase + Photosystem I PsaF, reaction centre subunit III + Putative tight adherence pilin protein F + Ti-type conjugative transfer relaxase TraA + 4-hydroxybenzoyl-CoA reductase, alpha subunit + Sporulation stage III, protein AF + Fibro-slime + B domain of TMEM189, localisation domain + Tetratricopeptide, SHNi-TPR domain + Putative lipoprotein, rSAM/lipoprotein system + Protein of unknown function DUF2811 + NFkB-p65-degrading zinc protease + Methane monooxygenase, gamma chain + Sporadic carbohydrate cluster 2-oxoglutarate-Fe(II) oxygenase + Integrin beta N-terminal + Conserved hypothetical protein CHP04046, FMN-dependent + Protein of unknown function DUF3846 + Methane monooxygenase, gamma chain, domain 2 + Methane monooxygenase, gamma chain, domain 1 + Phosphonate degradation operon associated HDIG domain protein + Coenzyme F420 hydrogenase, subunit beta + Peptide modification radical SAM enzyme + DNA phosphorothioation-dependent restriction protein DptH + Gas2-related domain + Cysteine desulfurase DndA + Coactivator CBP, KIX domain + BAG domain + Sulphur oxygenase reductase + Viral replication-associated protein, N-terminal + ABC transporter ATP-binding subunit, DevA type + Tetraspanin, EC2 domain + Antenna complex, alpha subunit conserved site + Pesticidal crystal protein, N-terminal + PH1570-like domain + NTF2 fold domain + Conserved hypothetical protein CHP02664, nitrate reductase-associated + DENN domain + YjzC-like protein + Centromere protein Cenp-F, leucine-rich repeat-containing domain + Putative stress-induced transcription regulator + P-type ATPase, subfamily IIA, PMR1-type + Protein of unknown function DUF1904 + Type-IV secretion system protein TraC + Type-F conjugative transfer system protein TrbI + Bleomycin resistance protein + Uncharacterised protein family, LppY/LpqO + Glycoside hydrolase, family 45 + Bacterial proteasome activator + Protein of unknown function DUF2690 + Phage terminase small subunit + GXWXG domain + Phosphotransferase system, maltose/glucose-specific subfamily IIC component + Protein of unknown function DUF229 + Autophagy protein Atg8 ubiquitin-like + Protein of unknown function DUF1556 + Immunodeficiency virus transactivating regulatory protein (Tat) + Type IV conjugative transfer protein TrbJ + Helicase Cas3, CRISPR-associated, Yersinia-type + Propionate--CoA ligase + Decaheme cytochrome, c-type, DmsE + Tyrosine-protein kinase ephrin type A/B receptor-like + Peptide-modifying radical SAM enzyme CbpB + VPEID-CTERM protein sorting domain + Exosortase E/protease, VPEID-CTERM system + Spore coat protein X/V + Cell division protein FtsN + Sigma-E processing peptidase SpoIIGA + RGS, subdomain 1 + Protein of unknown function DUF1173 + Polynucleotide kinase-phosphatase, C-terminal + Cobalamin (vitamin B12) biosynthesis protein CbiM + Lysine-2,3-aminomutase-related + Spanin, inner membrane subunit + Plastocyanin + Domain of unknown function DUF1910 + CheY binding + Lipoprotein, putative + Conserved hypothetical protein CHP03806, HNE0200 family + PelD, GGDEF domain + Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB + Domain of unknown function DUF2262 + Duffy antigen/chemokine receptor + Zinc finger, UBP-type + AmpG-like permease/Acetyl-coenzyme A transporter 1 + Immunity protein 26 + Signal transduction response regulator, propionate catabolism, transcriptional regulator PrpR + Circadian clock protein KaiB + MDMPI C-terminal + 1, 4-beta cellobiohydrolase + Zinc finger, HIT-type + Bride of sevenless protein + DNA topoisomerase II, eukaryotic-type + UV radiation resistance protein/autophagy-related protein 14 + Tryptophan 2,3-dioxygenase, bacterial + Kynurenine formamidase, bacteria + 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase + Poxvirus VLTF3, late transcription factor + Protein of unknown function DUF4943 + Acyltransferase, C-terminal domain + Exostosin , C-terminal + FYVE zinc finger + Pyrimidine dimer DNA glycosylase + Spore coat assembly protein CotJB, domain + Inverse autotransporter, beta-domain + Domain of unknown function DUF3421 + von Hippel-Lindau disease tumour suppressor, alpha domain + Sucrose phosphate synthase, sucrose phosphatase-like domain + Papillomavirus E7 + Cysteine desulfurase NifS, proteobacteria + Pleckstrin-like, plant + Uncharacterised conserved protein UCP015278 + TNFR/NGFR cysteine-rich region + F-box domain + T4 recombination endonuclease VII, dimerisation + Gcn5-related N-acetyltransferase (GNAT) domain, ATAT-type + mRNA capping enzyme, C-terminal + Stage III sporulation protein AC + Pectinesterase, Tyr active site + Pili assembly chaperone, conserved site + Rhabdovirus nucleocapsid, C-terminal + HD containing hydrolase-like enzyme + AbrB-like transcriptional regulator + Domain of unknown function DUF2027 + Protein of unknown function DUF3619 + Serine incorporator/TMS membrane protein + GUN4-like + Serine-tRNA ligase, class IIa, archaea + Protein of unknown function DUF4291 + Zinc finger, nuclear hormone receptor-type + Arp2/3 complex subunit 2/4 + L-fuculokinase + Protein of unknown function DUF4089 + Replication initiator A, N-terminal + Phasin, subfamily 2 + Delta antigen, N-terminal domain + Protein of unknown function DUF530 + GTP-sensing transcriptional pleiotropic repressor CodY + DNA helicase subunit AddA + Mitochondrial carrier protein + Protein N-terminal asparagine amidohydrolase + Monopolin complex subunit Lrs4/Mde4 + Protein of unknown function DUF2086 + Ax21 family + Histone H3/CENP-A + Folate-sensitive fragile site protein Fra10Ac1 + 5-dehydro-4-deoxyglucarate dehydratase + Type III secretion system needle length determinant, C-terminal domain + Sugar transferase, PEP-CTERM, Stp2 + Nickel-responsive transcriptional regulator NikR, proteobacteria + Formate-dependent nitrite reductase complex, subunit NrfF + Restriction endonuclease BpuSI, N-terminal domain + TLDc domain + Phenylacetic acid degradation protein PaaY + Protein of unknown function DUF2511 + Conserved hypothetical protein CHP04073, exosortase-affiliated + Peptidase S8A, tripeptidyl peptidase II + Sporadic carbohydrate cluster protein, LIC12192 family + CRISPR-associated protein Cas4, PREFRAN subtype + Glycosyl transferase, family 6 + T-complex 11 + Uncharacterised protein family YhfT + Restriction endonuclease, type II, MspI + Glutathione synthase, substrate-binding, eukaryotic + Bacteriophage T4, Gp8 + Villin headpiece + Cyclodileucine synthase + Restriction endonuclease, type II SfiI + Nitrogenase iron-iron, accessory protein AnfO + Protein of unknown function DUF3213 + Barnase + Uncharacterised protein family UPF0021, conserved site + Protein of unknown function DUF4824 + Alpha-2,3-sialyltransferase + Tim10/FAM136A-like domain + Protein of unknown function DUF829, TMEM53 + Protein of unknown function DUF3516 + Putative aromatic acid exporter, C-terminal + Cysteine oxygenase/2-aminoethanethiol dioxygenase + 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase + 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit + 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit + 7TM GPCR, serpentine receptor class e (Sre) + Protein of unknown function DUF4320 + Ciliary BBSome complex subunit 2, middle region + Phage tail tube protein 3 + Type III exporter system, secretion apparatus protein BsaZ + Uncharacterised protein family Ycf33 + Sigma factor regulator, N-terminal + Siderophore iron transporter 1/trichothecene efflux pump Tri12 + Ubiquitin-conjugating enzyme, active site + Anti-Sigma Factor A + Insect odorant-binding protein A10/Ejaculatory bulb-specific protein 3 + Legume-like lectin + Restriction endonuclease, type II, HaeIII + Pertactin, central region + Immunity protein Imm5 + Protein of unknown function DUF1660 + Protein of unknown function DUF1236 + Domain of unknown function DUF4314 + Protein of unknown function DUF4317 + Nuclear hormone receptor, ligand-binding domain + Double-stranded RNA-specific adenosine deaminase (DRADA) + Link domain + PGDYG protein + Molybdenum cofactor biosynthesis protein F, N-terminal + Agmatine deiminase + CRISPR-associated protein Cas5, bacterial + Negative regulator of genetic competence, MecA + Zinc finger, RING-CH-type + Photosystem II cytochrome b559, N-terminal + Domain of unknown function DUF4396 + Sporulation protein YunB + Sporulation stage III, protein AE + D-(-)-3-hydroxybutyrate oligomer hydrolase, putative + LydA-holin antagonist LydB + Protein of unknown function DUF3579 + PE-PPE, C-terminal + Schwannomin interacting protein 1 + Type III secretion system HrpE/YscL + Type III secretion system YscD/HrpQ + Peptidase M23A, B-lytic metalloendopeptidase + K+ transporting P-type ATPase, F subunit + Protein of unknown function DUF4133 + Peptidase C2, calpain, catalytic domain + Alpha-amylase C-terminal, prokaryotic + F420-dependent oxidoreductase-predicted, Rv1855c + Phosphotransferase system, sucrose-specific IIBC component + Uncharacterised conserved protein UCP037672 + Protein of unknown function DUF529 + Cathepsin propeptide inhibitor domain (I29) + Protein of unknown function DUF3873 + Dynein heavy chain, hydrolytic ATP-binding dynein motor region D1 + Apolipoprotein A/E + Protein of unknown function DUF5334 + C-terminal associated domain of TOPRIM + Domain of unknown function DUF5069 + Phage protein Gp45.2 + Carboxysome shell carbonic anhydrase + Phosphate butyryltransferase + Hypersensitivity response secretion-like, HrpJ + Immunity protein CdiI + Protein of unknown function DUF3258 + B transposition protein, C-terminal + F-actin capping protein, beta subunit, conserved site + 1-aminocyclopropane-1-carboxylate deaminase + Chromosome passenger complex (CPC) protein INCENP N-terminal + Restriction endonuclease, type II, HindVP + Zn(2)-C6 fungal-type DNA-binding domain + Domain of unknown function DUF3885 + D-fructose-responsive transcription factor + Carbon-monoxide dehydrogenase, large subunit + L-ribulose-5-phosphate 3-epimerase + Tudor domain + Copper amine oxidase + Herpesvirus major outer envelope glycoprotein + CDR ABC transporter + Sporulation stage V, protein AE + Relaxosome protein TraY + Fimbrial major subunit, CS1-type + Integrating conjugative element, PFGI-1, ParB + Conjugative transfer ATPase + Integrating conjugative element protein PFL_4710 + HEXXH motif domain + Radical SAM protein, BA_1875 family + Bacteriocin, class IIb, lactacin-related + Protein of unknown function DUF1590 + Protein of unknown function DUF4257) + Poly(ADP-ribose) polymerase, catalytic domain + Nuclear fusion protein, KAR5 + Uncharacterised protein family Ycf34 + Antirepressor protein ANT, N-terminal + Eukaryotic translation initiation factor 3-like domain + Bacteriophage P22, Orf201, C-terminal + Protein-tyrosine phosphatase, YopH, N-terminal + CRISPR-associated protein Csn2 subfamily St + Protein of unknown function DUF2624 + Protein of unknown function DUF1419 + Type III secretion protein, LcrG + TATA-box binding + Surfeit locus 4 + Protein of unknown function DUF4879 + Protein of unknown function DUF4876 + Malonate/sodium symporter MadM subunit, N-terminal + Cyclin, C-terminal domain + Protein of unknown function DUF620 + TOBE-like domain + Vacuolar protein sorting protein 11, C-terminal + CS domain + Small/middle T-antigen + Immunity protein 32 + Yop virulence translocation protein R + NADH:ubiquinone oxidoreductase, chain 2 + Protein of unknown function DUF4843 + Bacteriophage 82, GpQ + CofD-related protein, GAK system + Protein of unknown function DUF5004 + Protein of unknown function DUF1580 + Rubisco LSMT, substrate-binding domain + Galectin, carbohydrate recognition domain + Protein of unknown function DUF4363 + Domain of unknown function DUF4368 + Spore coat protein CotF-like + Protein of unknown function DUF5411 + Glyoxylate carboligase + Conserved hypothetical protein CHP04081, GSU1558 + Thioester reductase-like domain + Conserved hypotheical protein CHP04052 + HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 + Histidine phosphatase superfamily, clade-2 + Protein of unknown function DUF4900 + Uncharacterised protein YqbF domain + Uncharacterised protein family Ycf51 + Glycoside hydrolase, family 59 + Fork head domain conserved site 2 + Ion channel regulatory protein, UNC-93 + Natural product precursor, GG-Bacteroidales + Fascin domain + Transcription factor homeodomain, male germ-cell + TRPM, tetramerisation domain + Brinker DNA-binding domain + Tyrosine-protein kinase SYK/ZAP-70, inter-SH2 domain + Interferon/interleukin receptor domain + Protein of unknown function DUF3936 + Domain of unknown function DUF1842 + Xanthosine phosphorylase + GTP-binding protein, riobosome biogenesis, YqeH + CRISPR-associated protein Cas8a1/Csx13, Myxan subtype, N-terminal + cGMP-dependent protein kinase, N-terminal coiled-coil domain + Protein of unknown function DUF3836 + Ubiquitin/SUMO-activating enzyme E1 + [NiFe]-hydrogenase-3-type complex Eha, membrane protein EhaH, predicted + Bacterial toxin 23 + Gp5, C-terminal + F-box associated (FBA) domain + Non-ribosomal peptide synthase + Nitrilase-related, sll0784 + Dicarboxylate carrier MatC N-terminal + Domain of unknown function DUF4874 + HtrL protein + MRG domain + Protein of unknown function DUF694 + Type III secretion system regulator LcrR/Chaperone CesD2 + Chlorophyll A-B binding protein + Protein of unknown function DUF3172 + DNA replication factor RFC1, C-terminal + Protein of unknown function DUF3599 + 2-oxopent-4-enoate hydratase + Type-2 restriction enzyme, D3 domain + Gemin2/Brr1 + Alginate O-acetyl transferase AlgF + Glycosyl amidation-associated protein, WbuZ + N-terminal acetyltransferase A, auxiliary subunit + Phage tail tube protein 1 + Putative abortive phage resistance protein AbiGii toxin + Glutathione synthase, N-terminal, eukaryotic + Protein of unknown function DUF3408 + Protein FRG1 + Photosystem I PsaM, reaction centre + Eight-cysteine-cluster domain + Aerolysin + Rhodopsin, N-terminal + Integrase, C-terminal, retroviral + rSAM-associated Gly-rich repeat protein + Salicylate biosynthesis protein PchB + Nuclear pore localisation protein Npl4, ubiquitin-like domain + Glutathione synthase domain + Domain of unknown function DUF3566. transmembrane + Sulfolobus islandicus filamentous virus, Orf14 + Mitogen-activated protein (MAP) kinase, conserved site + Galactose-1-phosphate uridyl transferase, class II, conserved site + DUSAM domain + Myxococcus xanthus paralogous protein 2265 + Methionyl-tRNA synthetase, N-terminal heteromerisation domain + Phospholipase C, phosphatidylinositol-specific, Y domain + Stress-induced protein, KGG, repeat + Protein of unknown function DUF2491 + Domain of unknown function DUF4474 + Ribosome-inactivating protein + Vertebrate-like NAGS Gcn5-related N-acetyltransferase (GNAT) domain + KGK + General stress protein 17M-like domain + PapC, N-terminal domain + Zinc finger, TAZ-type + Rab-GTPase-TBC domain + Putative glycolipid-binding protein + CRISPR-associated endonuclease Cas9, bridge helix + Bor + Immunity protein 53 + Spore photoproduct lyase + Pkip-1 + Photosystem II D2 protein + Bacteriophage N4 adsorption protein A, C-terminal + Protein of unknown function DUF3243 + Protein of unknown function DUF3238 + Peptidase C14A, caspase catalytic domain + Membrane lipoprotein, lipid attachment site + RNA ligase, DRB0094 + Uncharacterised protein family FAM171 + GPCR fungal pheromone mating factor, STE2 + Lipid-binding, putative + WYL domain containing protein + Putative member of DMT superfamily + Meiotic recombination, Spo11 + Chlamydia cysteine-rich outer membrane protein 6 + Uncharacterised conserved protein UCP028477 + Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal + Ribosomal protein L37e, conserved site + P40 nucleoprotein, subdomain 1, Borna disease virus + Protein of unknown function DUF3370 + HeH/LEM domain + SUKH-3 immunity protein + Bypass of forespore C, C-terminal + Claudin, conserved site + [NiFe]-hydrogenase-3-type complex Eha, subunit EhaM + Sporulation transcription factor Spo0A + 4-hydroxybenzoyl-CoA reductase, beta subunit + Lipopolysaccharide core heptose(II) kinase + Cytochrome b-c1 complex subunit 7 + Type IV pilus biogenesis PilP + Reeler domain + 2',3'-cyclic-nucleotide 3'-phosphodiesterase + Quinone modification maturase, putative + Poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA + PapC-like, C-terminal domain + Protein of unknown function DUF2887 + Protein of unknown function DUF3764 + Domain of unknown function DUF4033 + Domain of unknown function DUF4034 + Phosphotransferase system, trehalose-specific IIBC component + Lysyl oxidase + Endosialidase, beta propeller domain + Endosialidase, beta barrel domain + Protein of unknown function DUF5132 + WLM domain + Uricase + Glycosyl hydrolase family 98, central domain + Protein of unknown function DUF5455 + Invertebrate-type lysozyme + Lepidopteran low molecular weight lipoprotein + Protein of unknown function DUF993 + SPRY domain + Vacuolar (H+)-ATPase G subunit + Protein of unknown function DUF3683 + Virus, major capsid protein, C-terminal + Mercury(II) reductase + MoaF, C-terminal domain + Histone H2A/H2B/H3 + Villin/Gelsolin + Cyclohexanecarboxyl-CoA dehydrogenase + 2-ketocyclohexanecarboxyl-CoA hydrolase + Glutamate decarboxylase + Uncharacterised protein family Ycf66 + Poly-beta-1,6 N-acetyl-D-glucosamine synthase PgaC/IcaA + Glycoside hydrolase, family 70, catalytic domain + Domain of unknown function DUF4431 + Phage tail tube protein family + Phage tail tube protein, lambda-like + Cation/H+ exchanger, CPA1 family, bacteria + Annexin repeat + Phosphatidate cytidylyltransferase, mitochondrial + Alpha-2-glucosyltransferase Alg10 + Transport accessory protein MmpS + Domain of unknown function DUF4123 + Protein of unknown function DUF4265 + Uncharacterised conserved protein withTPR-like repeats + Anti-sigma factor CnrY + IgGFc-binding protein, N-terminal + Type III secretion system, needle protein + Pullulanase, type I + Sodium/pantothenate symporter + Circadian clock protein KaiA, C-terminal + DltD + Ribosomal protein L24e, conserved site + SPARC/Testican, calcium-binding domain + Drought induced 19 protein type, zinc-binding domain + Domain of unknown function DUF4183 + Protein of unknown function DUF4184 + Peptidase M10A, cysteine switch, zinc binding site + Protein of unknown function DUF4348 + Transferase + Domain of unknown function DUF4830 + HAP1, N-terminal + Peptidase A25, germination protease + Kinetochore subunit NKP2 + Protein of unknown function DUF3227 + Immunity protein 63 + Zinc finger, PHD-type, conserved site + Ectoine dioxygenase + Ulp1 protease family, C-terminal catalytic domain + Transcription factor, choline sulphate-utilisation, putative + Sporulation initiation factor Spo0A, C-terminal + Domain of unknown function DUF1793 + Fibronectin-attachment + Domain of unknown function DUF1400 + Csa1 family + ATPase assembly factor ATP10 + KELK-motif containing domain + ShlB, POTRA domain + Peptidase S26A, superoxide dismutase maturation protease, nickel-type + Tox-URI2 domain + Transaldolase, Staphylococcus-type + PKC-activated phosphatase-1 inhibitor + YiaAB two helix + Cullin protein, neddylation domain + Anthrax toxin, edema factor, central + Protein of unknown function DUF3253 + Major facilitator superfamily, aromatic acid:H+ symporter family + GTF2I-like repeat + Replication protein + Cys-rich repeat, Myxococcales-type + CAP-associated domain + CRISPR-associated endonuclease Cas9, PAM-interacting domain + Protein of unknown function DUF3072 + Janus + Papillomavirus E2, N-terminal + Domain of unknown function DUF4101 + Probable glutamyl-tRNA(Gln) amidotransferase subunit C, archaea + 2-aminoethylphosphonate ABC transport system, permease protein, putative + DMSO reductase family, type II, chaperone + CRISPR-associated protein A791736 + Conserved hypothetical protein CHP03982 + Conserved hypothetical protein CHP03894 + Type IVb secretion, IcmS, effector-recruitment + Huwentoxin-1 family + Phosphate-starvation-induced PsiF repeat + Beta tubulin, autoregulation binding site + Domain of unknown function DUF4429 + Glycerol-3-phosphate dehydrogenase, GlpA subunit + YkvR-like domain + TonB-system energizer ExbB type-1 + Fatty acid synthase, domain 2 + Uncharacterised protein family UPF0686 + Protein of unknown function DUF1146 + Fungal dockerin domain + Herpesvirus glycoprotein J + Peptide-N-glycosidase F, N-terminal + Conjugative coupling factor TraG/TraD, PFGI-1 + Exosortase, archaea + TerB-C domain + Domain of unknown function DUF3197 + Glucosyl transferase II + Protein of unknown function DUF4337 + Cytochrome c oxidase subunit IV, actinobacteria + DpnD/PcfM-like protein + YwiC-like protein + Protein of unknown function DUF2680 + Profilin + TSC-22 / Dip / Bun + Squalene hopene cyclase + Type II restriction endonuclease SinI + Ubiquitin fusion degradation protein Ufd1-like + Cytochrome c oxidase cbb3-type, CcoQ + Anaerobic dimethyl sulphoxide reductase, subunit A, DmsA/YnfE + HofP protein + Bacteriophage T7, Gp17.5, holin + Alpha-mannosyltransferase + Pseudo-rSAM protein, GG-Bacteroidales system + Sporulation protein YabP + XK-related protein + RNA polymerase sigma-E type + Sporulation stage IV, protein A + Post-transcriptional regulator + DNA phosphorothioation system restriction enzyme, putative + Protein of unknown function DUF3093 + TonB-dependent vitamin B12 transporter BtuB + Molybdopterin synthase sulfurylase MoeB + P-aminobenzoate N-oxygenase AurF + Anti-sigma F factor antagonist + Protein of unknown function DUF3496 + Asparagine synthase family amidotransferase + tRNA (uracil-O(2)-)-methyltransferase + Peridinin-chlorophyll A binding protein + Lipase/vitellogenin + Photosystem I PsaE, reaction centre subunit IV + Protein of unknown function DUF2735 + Polynucleotide kinase-phosphatase, ligase domain + Photosystem II cytochrome b559, conserved site + Xyloglucan fucosyltransferase + HMW kininogen + Lyase, catalytic + NE1680-like domain + Tox-PL-2 domain + Tox-MPTase3 domain + Protein of unknown function DUF2105, membrane + Protein of unknown function DUF2108, membrane + Protein of unknown function DUF2109, membrane + Sporulation lipoprotein YhcN/YlaJ-like + Spore cortex biosynthesis protein, YabQ-like + Transcription elongation factor S-II, central domain + Domain of unknown function DUF3972 + Thiamine kinase + Protein of unknown function DUF3787 + Lipoxygenase, domain 3 + Protein of unknown function DUF5363 + Uncharacterised protein family Ycf55 + PDZ-like domain + PPC89 centrosome localisation domain + Sialidase, N-terminal + Sphingolipid delta4-desaturase, N-terminal + Glutathione S-transferases, subfamily 4, C-terminal + Integrating conjugative element protein, PFL4705 + Integrating conjugative element protein, PFL4711 + AIR synthase-related protein, sll0787 family + Adenosine/AMP deaminase N-terminal + Periplasmic lysozyme inhibitor, I-type + Soil-associated protein DUF3738 + Pili assembly chaperone, bacterial + ESX-1 secretion-associated protein EspC + Alpha trans-inducing protein (Alpha-TIF) + CamS sex pheromone cAM373 + Tryptophan transporter TrpP + Phosphoribosyl-dephospho-CoA transferase + PRTase ComF-like + ParB-related, ThiF-related cassette, protein E + Lunapark domain + Protein of unknown function DUF2301 + Mediator complex, subunit Med29, metazoa + Nuclear protein DGCR14 + Tryptophanase + Phosphonate utilization transcriptional regulator PhnR + Alpha-2,8-polysialyltransferase + Protein of unknown function DUF1493 + Domain of unknown function DUF1868 + P-type conjugative transfer protein VirB9 + Bacterial exotoxin B + Protein of unknown function DUF4259 + 6-carboxyhexanoate--CoA ligase + Transmembrane Fragile-X-F-associated protein + Cellulose biosynthesis, BcsF/YhjT + Protein of unknown function DUF2101, membrane + DNA-directed RNA polymerase subunit beta/EpuA + Putative RNA polymerase (calciviral)/capsid protein + Trehalose synthase/probable maltokinase, C-terminal domain + Uncharacterised membrane protein Ta0354, soluble domain + Protein of unknown function DUF3196 + Peptidase family A1 domain + Domain of unknown function DUF4781 + Ninjurin + Protein of unknown function DUF4278 + Egg lysin (Sperm-lysin) + Lipoprotein, type 6 + Quinohemoprotein amine dehydrogenase, beta subunit + Photosynthetic reaction centre, cytochrome c subunit + Glutaredoxin-like protein NrdH + Proteinase inhibitor I25, cystatin, conserved site + ATP-dependent RNA helicase RhlB + Putative outer membrane core complex of type IVb secretion + Transcription activator CII + Galactosyltransferase, N-terminal + YyzF-like protein + Domain of unknown function, DUF3672 + Fibronectin, type II, collagen-binding + Channel forming colicin, C-terminal cytotoxic + SAGA complex, Sgf11 subunit + Protein of unknown function DUF2673 + Thiostrepton-resistance methylase, N-terminal + Protein of unknown function DUF4902 + Protein of unknown function DUF1450 + Domain of unknown function DUF4955 + AIG1-type guanine nucleotide-binding (G) domain + At2g17340, N-terminal + Protein of unknown function DUF3789 + NDP-hexose 2,3-dehydratase + Protein of unknown function DUF2076 + Membrane protein of 12 TMs + Uncharacterised protein family CHP04562 + Transcriptional repressor of class III stress genes + Domain of unknown function DUF1736 + NAD(P)H-quinone oxidoreductase subunit O + Glycine N-acyltransferase, C-terminal + Mitochondrial glycoprotein + Conserved hypothetical protein CHP03084 + Acid ceramidase, N-terminal + Putative stage IV sporulation YqfD + Protein of unknown function DUF1273 + LRR-containing bacterial E3 ligase, N-terminal + Conserved oligomeric Golgi complex subunit 8 + YopX-like domain, N-terminal + Protein of unknown function DUF2605 + Bacteriophage T4, P15K, RNA polymerase binding + CRISPR-associated protein Cas1, MYXAN subtype + Glucose-6-phosphate dehydrogenase assembly protein OpcA + L-asparaginase, type II + Ta0938 + Plectin repeat + Protein of unknown function DUF1688 + Copper amine oxidase, N3-terminal + Copper amine oxidase, N2-terminal + Mannosyltransferase, DXD + Protein of unknown function DUF2633 + Sulfocyanin + Cysteine desulfurase, sulphur acceptor subunit CsdE + CRISPR-associated protein Csx3 + Bacterial phospholipase C, phosphocholine-specific + Type III secretion system regulator, LcrR + Type III secretion regulator, YopN/LcrE/InvE/MxiC + Type III secretion system chaperone, YscW + Uncharacterised protein family Ycf23 + Phycobilisome degradation protein NblA + Arv1 protein + Domain of unknown function DUF4964 + Hydroxymethylglutaryl-CoA synthase, prokaryotic + SbmA/BacA-like + RNA polymerase sigma-24-related + CLASP N-terminal domain + Protein of unknown function DUF1931 + Domain X + Flagellar transcriptional activator FlhD + Protein of unknown function DUF2181 + Dense granule Gra6 protein + mRNA capping enzyme, catalytic domain + E6 early regulatory protein + Glycosyl transferase, family 48 + Putative site-specific recombinase Gcr + Protein of unknown function DUF726 + Fanconi anemia group M protein, MHF binding domain + Protein of unknown function DUF4844 + Hyaluronidase + Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal + Paired domain + Type III secretion system effector YopR + Domain of unknown function DUF4422 + Thrombospondin, C-terminal + Protein of unknown function DUF3605 + Protein of unknown function DUF3606 + TUG ubiquitin-like domain + Copper amine oxidase, C-terminal + Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding + Germin + S-adenosylmethionine decarboxylase, conserved site + DMSO reductase family, type II, iron-sulphur subunit + Auxin-binding protein + 7-carboxy-7-deazaguanine synthase + Alcohol dehydrogenase, phosphonate catabolism-associated, putative + Trimethylamine-N-oxide reductase TorA + Replication factor A protein 3 + Sporulation stage V, protein T + Uncharacterised protein YhfZ, C-terminal domain + Domain of unknown function, CHP04279 + Cellulose synthase, subunit C + Ribosomal protein L14e domain + Protein of unknown function DUF2167, membrane + Protein of unknown function DUF2173 + Protein GAPT + GDP-fucose protein O-fucosyltransferase + Restriction endonuclease, type II, PvuII + Pumilio RNA-binding repeat + Protein of unknown function DUF723 + L1 transposable element, dsRBD-like domain + Protein of unknown function DUF2631 + Partial AB-hydrolase lipase domain + Protein of unknown function DUF4852 + Gonadotropin, beta subunit, conserved site + Nitrogenase alpha chain + Zinc finger, CCCH-type, TRM13 + Acyl-CoA oxidase, C-terminal + Pentaxin, conserved site + Tetracycline transcriptional regulator, TetR + Sec7 domain + Entry exclusion lipoprotein TrbK + Coenzyme F420 hydrogenase, subunit gamma + A-factor biosynthesis hotdog domain + Clostridium phage holin + Protein of unknown function DUF5414 + Peptidase aspartic, putative + Protein of unknown function DUF1517 + Protein of unknown function DUF4121 + Carboxypeptidase M99, beta-barrel domain + Protein of unknown function DUF4267 + Domain of unknown function DUF4274 + PiggyBac transposable element-derived protein + DnaJ-like protein C11, C-terminal + Phosphonate utilization associated transmembrane protein, putative + Coenzyme F390 synthetase + Protein of unknown function DUF2469 + Life-span regulatory factor + Arylsulfotransferase, Ig-like domain + Thiol-activated cytolysin C-terminal + Antiactivator protein ExsD + 5-methylthioadenosine/S-adenosylhomocysteine nucleosidase, putative + 47.0 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + 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b/emgapi/templates/ebi_search/projects.xml new file mode 100644 index 000000000..d8c9d2d04 --- /dev/null +++ b/emgapi/templates/ebi_search/projects.xml @@ -0,0 +1,40 @@ + + EMG_Project + EMG Projects โ€“ studies analysed by MGnify + {% now "Y-m-d" %} + {{ count }} + + {% for addition in additions %} + {% with addition.study as study %} + + {{ study.study_name | escape }} + {{ study.study_abstract | escape }} + + + + + + {{ study.secondary_accession }} + {{ study.biome.biome_name }} + + {% for biome_element in addition.biome_list %} + {% if forloop.first %} + {{ biome_element | escape }} + {% else %} + {{ biome_element | escape }} + {% endif %} + {% endfor %} + + {{ study.centre_name | escape }} + + + + {% for analysis in study.analyses.all %} + + {% endfor %} + + + {% endwith %} + {% endfor %} + + diff --git a/emgapianns/models.py b/emgapianns/models.py index b07ea59b7..6639cafb1 100644 --- a/emgapianns/models.py +++ b/emgapianns/models.py @@ -1,5 +1,6 @@ #!/usr/bin/env python # -*- coding: utf-8 -*- +from functools import cached_property # Copyright 2019 EMBL - European Bioinformatics Institute # @@ -106,86 +107,108 @@ class BaseAnalysisJobAnnotation(mongoengine.EmbeddedDocument): class AnalysisJobGoTermAnnotation(BaseAnalysisJobAnnotation): - go_term = mongoengine.ReferenceField(GoTerm, required=True) + go_term = mongoengine.LazyReferenceField(GoTerm, required=True) + + @cached_property + def materialised_go_term(self): + return self.go_term.fetch() @property def accession(self): - return self.go_term.accession + return self.materialised_go_term.accession @property def description(self): - return self.go_term.description + return self.materialised_go_term.description @property def lineage(self): - return self.go_term.lineage + return self.materialised_go_term.lineage class AnalysisJobInterproIdentifierAnnotation(BaseAnalysisJobAnnotation): - interpro_identifier = mongoengine.ReferenceField(InterproIdentifier, - required=True) + interpro_identifier = mongoengine.LazyReferenceField( + InterproIdentifier, + required=True + ) + + @cached_property + def materialised_interpro_identifier(self): + return self.interpro_identifier.fetch() @property def accession(self): - return self.interpro_identifier.accession + return self.materialised_interpro_identifier.accession @property def description(self): - return self.interpro_identifier.description + return self.materialised_interpro_identifier.description @property def lineage(self): - return self.interpro_identifier.lineage + return self.materialised_interpro_identifier.lineage class AnalysisJobKeggModuleAnnotation(mongoengine.EmbeddedDocument): """KEGG modules on a given Analysis Job. """ - module = mongoengine.ReferenceField(KeggModule, required=True) + module = mongoengine.LazyReferenceField(KeggModule, required=True) completeness = mongoengine.FloatField(default=0.0) matching_kos = mongoengine.ListField(mongoengine.StringField(), default=list) missing_kos = mongoengine.ListField(mongoengine.StringField(), default=list) + @cached_property + def materialised_module(self): + return self.module.fetch() + @property def accession(self): - return self.module.accession + return self.materialised_module.accession @property def description(self): - return self.module.description + return self.materialised_module.description @property def name(self): - return self.module.name + return self.materialised_module.name class AnalysisJobPfamAnnotation(BaseAnalysisJobAnnotation): """Pfam on a given Analysis Job. """ - pfam_entry = mongoengine.ReferenceField(PfamEntry, required=True) + pfam_entry = mongoengine.LazyReferenceField(PfamEntry, required=True) + + @cached_property + def materialised_pfam_entry(self): + return self.pfam_entry.fetch() @property def accession(self): - return self.pfam_entry.accession + return self.materialised_pfam_entry.accession @property def description(self): - return self.pfam_entry.description + return self.materialised_pfam_entry.description class AnalysisJobCOGAnnotation(BaseAnalysisJobAnnotation): """COG on a given Analysis Job. """ - cog = mongoengine.ReferenceField(COG, required=True) + cog = mongoengine.LazyReferenceField(COG, required=True) + + @cached_property + def materialised_cog(self): + return self.cog.fetch() @property def accession(self): - return self.cog.accession + return self.materialised_cog.accession @property def description(self): - return self.cog.description + return self.materialised_cog.description class AnalysisJobGenomePropAnnotation(mongoengine.EmbeddedDocument): @@ -199,44 +222,56 @@ class AnalysisJobGenomePropAnnotation(mongoengine.EmbeddedDocument): (PARTIAL_PRESENCE, 'Partial'), (NO_PRESENCE, 'No'), ) - genome_property = mongoengine.ReferenceField(GenomeProperty, required=True) + genome_property = mongoengine.LazyReferenceField(GenomeProperty, required=True) presence = mongoengine.IntField(required=True, choices=PRESENCE_CHOICES) + @cached_property + def materialised_genome_property(self): + return self.genome_property.fetch() + @property def accession(self): - return self.genome_property.accession + return self.materialised_genome_property.accession @property def description(self): - return self.genome_property.description + return self.materialised_genome_property.description class AnalysisJobKeggOrthologAnnotation(BaseAnalysisJobAnnotation): """KEGG KO on a given Analysis Job. """ - ko = mongoengine.ReferenceField(KeggOrtholog, required=True) + ko = mongoengine.LazyReferenceField(KeggOrtholog, required=True) + + @cached_property + def materialised_ko(self): + return self.ko.fetch() @property def accession(self): - return self.ko.accession + return self.materialised_ko.accession @property def description(self): - return self.ko.description + return self.materialised_ko.description class AnalysisJobAntiSmashGCAnnotation(BaseAnalysisJobAnnotation): """antiSMASH gene cluster on a given Analysis Job """ - gene_cluster = mongoengine.ReferenceField(AntiSmashGeneCluster, required=True) + gene_cluster = mongoengine.LazyReferenceField(AntiSmashGeneCluster, required=True) + + @cached_property + def materialised_gene_cluster(self): + return self.gene_cluster.fetch() @property def accession(self): - return self.gene_cluster.accession + return self.materialised_gene_cluster.accession @property def description(self): - return self.gene_cluster.description + return self.materialised_gene_cluster.description class BaseAnalysisJob(mongoengine.Document): @@ -333,39 +368,43 @@ class Organism(mongoengine.Document): class AnalysisJobOrganism(mongoengine.EmbeddedDocument): count = mongoengine.IntField(required=True) - organism = mongoengine.ReferenceField(Organism) + organism = mongoengine.LazyReferenceField(Organism) + + @cached_property + def materialised_organism(self): + return self.organism.fetch() @property def lineage(self): - return self.organism.lineage + return self.materialised_organism.lineage @property def ancestors(self): - return self.organism.ancestors + return self.materialised_organism.ancestors @property def hierarchy(self): - return self.organism.hierarchy + return self.materialised_organism.hierarchy @property def domain(self): - return self.organism.domain + return self.materialised_organism.domain @property def name(self): - return self.organism.name + return self.materialised_organism.name @property def parent(self): - return self.organism.parent + return self.materialised_organism.parent @property def rank(self): - return self.organism.rank + return self.materialised_organism.rank @property def pipeline_version(self): - return self.organism.pipeline_version + return self.materialised_organism.pipeline_version class EMGMeta: pk_field = 'lineage' diff --git a/emgapianns/utils.py b/emgapianns/utils.py new file mode 100644 index 000000000..25e715876 --- /dev/null +++ b/emgapianns/utils.py @@ -0,0 +1,25 @@ +import logging +from pymongo import monitoring + + +class MongoCommandLogger(monitoring.CommandListener): + + def started(self, event): + logging.debug( + f"Command {event.command}" + ) + logging.info( + f"Command {event.command_name} with request id {event.request_id} started on server {event.connection_id}" + ) + + def succeeded(self, event): + logging.info( + f"Command {event.command_name} with request id {event.request_id} on server {event.connection_id} " + f"succeeded in {event.duration_micros} microseconds" + ) + + def failed(self, event): + logging.info( + f"Command {event.command_name} with request id {event.request_id} on server {event.connection_id} " + f"failed in {event.duration_micros} microseconds" + ) diff --git a/emgcli/__init__.py b/emgcli/__init__.py index ff3a98ea4..57d8f469a 100644 --- a/emgcli/__init__.py +++ b/emgcli/__init__.py @@ -1 +1 @@ -__version__: str = "2.4.40" +__version__: str = "2.4.44" diff --git a/emgcli/settings.py b/emgcli/settings.py index d16bfa029..4fb645d91 100644 --- a/emgcli/settings.py +++ b/emgcli/settings.py @@ -37,6 +37,9 @@ from os.path import expanduser from corsheaders.defaults import default_headers +from pymongo import monitoring + +from emgapianns.utils import MongoCommandLogger try: from YamJam import yamjam, YAMLError @@ -45,7 +48,6 @@ logger = logging.getLogger(__name__) - # Build paths inside the project like this: os.path.join(BASE_DIR, ...) BASE_DIR = os.path.dirname(os.path.dirname(os.path.abspath(__file__))) EMG_CONFIG = os.environ.get( @@ -161,8 +163,15 @@ } } -# Quick-start development settings - unsuitable for production -# See https://docs.djangoproject.com/en/1.11/howto/deployment/checklist/ +if EMG_CONF.get('emg', {}).get('log_db_queries', False): + monitoring.register(MongoCommandLogger()) + LOGGING['loggers']['django.db.backends'] = { + 'handlers': ['default', 'console'], + 'level': 'DEBUG', + 'propagate': False, + } + LOGGING['loggers']['']['level'] = 'DEBUG' + def create_secret_key(var_dir): secret_key = None diff --git a/pyproject.toml b/pyproject.toml index 610add692..cd268fd7b 100644 --- a/pyproject.toml +++ b/pyproject.toml @@ -117,7 +117,7 @@ max-line-length = 119 """ [tool.bumpversion] -current_version = "2.4.40" +current_version = "2.4.44" [[tool.bumpversion.files]] filename = "emgcli/__init__.py" diff --git a/tests/api/test_study.py b/tests/api/test_study.py index b665c70b4..49ac8e3e6 100644 --- a/tests/api/test_study.py +++ b/tests/api/test_study.py @@ -1,5 +1,6 @@ #!/usr/bin/env python # -*- coding: utf-8 -*- +import datetime # Copyright 2020 EMBL - European Bioinformatics Institute # @@ -45,7 +46,7 @@ def test_details(self, client, study): assert _attr['study-abstract'] == "abcdefghijklmnoprstuvwyz" assert _attr['study-name'] == "Example study name SRP01234" assert _attr['data-origination'] == "HARVESTED" - assert _attr['last-update'] == "1970-01-01T00:00:00" + assert _attr['last-update'][:4] == datetime.datetime.now().isoformat()[:4] assert _attr['bioproject'] == "PRJDB1234" assert _attr['is-private'] == False @@ -93,7 +94,7 @@ def test_csv(self, client, studies): "\"study_name\"", "\"url\"" ]) - first_row = ",".join([ + first_row = [ "\"MGYS00000001\"", "\"\"", "\"PRJDB0001\"", @@ -101,7 +102,7 @@ def test_csv(self, client, studies): "\"HARVESTED\"", "\"\"", "False", - "\"1970-01-01T00:00:00\"", + None, "\"\"", "\"\"", "\"\"", @@ -110,11 +111,16 @@ def test_csv(self, client, studies): "\"\"", "\"Example study name 1\"", "\"http://testserver/v1/studies/MGYS00000001.csv\"" - ]) + ] rows = content.splitlines() assert len(rows) == 50 assert expected_header == rows[0] - assert first_row == rows[1] + first_row_response = rows[1].split(',') + assert len(first_row_response) == len(first_row) + for response_element, expected_element in zip(first_row_response, first_row): + if expected_element is not None: + assert response_element == expected_element + diff --git a/tests/test_utils/emg_fixtures.py b/tests/test_utils/emg_fixtures.py index 17e5b706a..f8275c9a8 100644 --- a/tests/test_utils/emg_fixtures.py +++ b/tests/test_utils/emg_fixtures.py @@ -127,7 +127,7 @@ def super_study(study, study_private, biome): @pytest.fixture def studies(biome): studies = [] - for pk in range(1, 50): + for pk in range(49, 0, -1): studies.append( emg_models.Study( biome=biome,