diff --git a/.github/workflows/docker.yml b/.github/workflows/docker.yml
new file mode 100644
index 000000000..46f135813
--- /dev/null
+++ b/.github/workflows/docker.yml
@@ -0,0 +1,51 @@
+name: Docker
+on:
+  release:
+    types: [published]
+  workflow_dispatch:
+    inputs:
+      docker-tag:
+        description: 'Docker image tag (such as: release_111.0)'
+        required: true
+
+jobs:
+  docker:
+    runs-on: ubuntu-latest
+    steps:
+      - name: Checkout repository
+        uses: actions/checkout@v3
+
+      - name: Extract metadata
+        id: meta
+        uses: docker/metadata-action@v4
+        with:
+          images: ensemblorg/ensembl-vep
+          tags: |
+            # example of Docker tag: release_109.3 (for consistency with previous releases)
+            type=match,pattern=\d+\.\d+,group=0,prefix=release_
+            latest
+            ${{ github.event.inputs.docker-tag }}
+
+      - name: Set up QEMU
+        uses: docker/setup-qemu-action@v2
+
+      - name: Set up Docker Buildx
+        uses: docker/setup-buildx-action@v2
+        with:
+          platforms: linux/amd64,linux/arm64
+
+      - name: Login to DockerHub
+        uses: docker/login-action@v2
+        with:
+          username: ${{ secrets.DOCKERHUB_USER }}
+          password: ${{ secrets.DOCKERHUB_TOKEN }}
+
+      - name: Build and push
+        uses: docker/build-push-action@v4
+        with:
+          context: .
+          file: docker/Dockerfile
+          push: true
+          tags: ${{ steps.meta.outputs.tags }}
+          labels: ${{ steps.meta.outputs.labels }}
+          platforms: linux/amd64,linux/arm64