diff --git a/code/__DEFINES/traits/declarations.dm b/code/__DEFINES/traits/declarations.dm
index bb0a65fc5d2..5a00323aacd 100644
--- a/code/__DEFINES/traits/declarations.dm
+++ b/code/__DEFINES/traits/declarations.dm
@@ -164,6 +164,8 @@ Remember to update _globalvars/traits.dm if you're adding/removing/renaming trai
 #define TRAIT_NOBLOOD "noblood"
 /// This just means that the carbon will always have functional liverless metabolism
 #define TRAIT_LIVERLESS_METABOLISM "liverless_metabolism"
+/// This carbon can't be overdosed by chems
+#define TRAIT_OVERDOSEIMMUNE "overdose_immune"
 /// Humans with this trait cannot be turned into zombies
 #define TRAIT_NO_ZOMBIFY "no_zombify"
 /// Carbons with this trait can't have their DNA copied by diseases nor changelings
diff --git a/code/_globalvars/traits/_traits.dm b/code/_globalvars/traits/_traits.dm
index 7ec768e619a..d9e28da2988 100644
--- a/code/_globalvars/traits/_traits.dm
+++ b/code/_globalvars/traits/_traits.dm
@@ -320,6 +320,7 @@ GLOBAL_LIST_INIT(traits_by_type, list(
 		"TRAIT_NUKEIMMUNE" = TRAIT_NUKEIMMUNE,
 		"TRAIT_OIL_FRIED" = TRAIT_OIL_FRIED,
 		"TRAIT_ORBITING_FORBIDDEN" = TRAIT_ORBITING_FORBIDDEN,
+		"TRAIT_OVERDOSEIMMUNE" = TRAIT_OVERDOSEIMMUNE,
 		"TRAIT_OVERWATCH_IMMUNE" = TRAIT_OVERWATCH_IMMUNE,
 		"TRAIT_OVERWATCHED" = TRAIT_OVERWATCHED,
 		"TRAIT_PACIFISM" = TRAIT_PACIFISM,
diff --git a/code/modules/mob/living/carbon/human/_species.dm b/code/modules/mob/living/carbon/human/_species.dm
index 1215179d0ef..9183b2e4ac5 100644
--- a/code/modules/mob/living/carbon/human/_species.dm
+++ b/code/modules/mob/living/carbon/human/_species.dm
@@ -1068,7 +1068,7 @@ GLOBAL_LIST_EMPTY(features_by_species)
 		affected.blood_volume = min(affected.blood_volume + round(chem.volume, 0.1), BLOOD_VOLUME_MAXIMUM)
 		affected.reagents.del_reagent(chem.type)
 		return COMSIG_MOB_STOP_REAGENT_CHECK
-	if(!chem.overdosed && chem.overdose_threshold && chem.volume >= chem.overdose_threshold)
+	if(!chem.overdosed && chem.overdose_threshold && chem.volume >= chem.overdose_threshold && !HAS_TRAIT(affected, TRAIT_OVERDOSEIMMUNE))
 		chem.overdosed = TRUE
 		chem.overdose_start(affected)
 		affected.log_message("has started overdosing on [chem.name] at [chem.volume] units.", LOG_GAME)
diff --git a/code/modules/mob/living/carbon/human/species_types/android.dm b/code/modules/mob/living/carbon/human/species_types/android.dm
index dec4fd9e306..5988ad3b890 100644
--- a/code/modules/mob/living/carbon/human/species_types/android.dm
+++ b/code/modules/mob/living/carbon/human/species_types/android.dm
@@ -15,6 +15,7 @@
 		TRAIT_NO_DNA_COPY,
 		TRAIT_NO_PLASMA_TRANSFORM,
 		TRAIT_NO_UNDERWEAR,
+		TRAIT_OVERDOSEIMMUNE,
 		TRAIT_PIERCEIMMUNE,
 		TRAIT_RADIMMUNE,
 		TRAIT_RESISTCOLD,
diff --git a/code/modules/reagents/chemistry/holder.dm b/code/modules/reagents/chemistry/holder.dm
index 20d4da62f2b..5f9d7f81995 100644
--- a/code/modules/reagents/chemistry/holder.dm
+++ b/code/modules/reagents/chemistry/holder.dm
@@ -765,7 +765,7 @@
 		if(!reagent.metabolizing)
 			reagent.metabolizing = TRUE
 			reagent.on_mob_metabolize(owner)
-		if(can_overdose)
+		if(can_overdose && !HAS_TRAIT(owner, TRAIT_OVERDOSEIMMUNE))
 			if(reagent.overdose_threshold)
 				if(reagent.volume >= reagent.overdose_threshold && !reagent.overdosed)
 					reagent.overdosed = TRUE