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FHIR-genomics-reporting.xml
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FHIR-genomics-reporting.xml
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<?xml version="1.0" encoding="UTF-8"?>
<specification xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" ballotUrl="http://hl7.org/fhir/uv/genomics-reporting/2024Jan" ciUrl="http://build.fhir.org/ig/HL7/genomics-reporting" defaultVersion="3.0.0" defaultWorkgroup="cg" gitUrl="https://github.com/HL7/genomics-reporting" url="http://hl7.org/fhir/uv/genomics-reporting">
<version code="current" url="http://build.fhir.org/ig/HL7/genomics-reporting"/>
<version code="3.0.0" url="http://hl7.org/fhir/uv/genomics-reporting/STU3"/>
<version code="3.0.0-ballot" url="http://hl7.org/fhir/uv/genomics-reporting/2024Jan"/>
<version code="2.0.0" url="http://hl7.org/fhir/uv/genomics-reporting/STU2"/>
<version code="1.1.0" deprecated="true" url="http://hl7.org/fhir/uv/genomics-reporting/2021May"/>
<version code="1.0.0" url="http://hl7.org/fhir/uv/genomics-reporting/STU1"/>
<version code="0.3.0" deprecated="true" url="http://hl7.org/fhir/uv/genomics-reporting/2019Jan"/>
<version code="0.1.0" deprecated="true" url="http://hl7.org/fhir/uv/genomics-reporting/2018May"/>
<version code="1.0" deprecated="true" url="http://hl7.org/fhir/uv/genomics-reporting/STU1"/>
<version code="3.0.0-BALLOT" deprecated="true"/>
<artifactPageExtension value="-definitions"/>
<artifactPageExtension value="-examples"/>
<artifactPageExtension value="-mappings"/>
<artifact deprecated="true" id="Observation/ATM-insertion-molc" key="Observation-ATM-insertion-molc" name="ATM-insertion-molc"/>
<artifact deprecated="true" id="Observation/ATM-missense-significance" key="Observation-ATM-missense-significance" name="ATM-missense-significance"/>
<artifact deprecated="true" id="Observation/ATM-missense-var" key="Observation-ATM-missense-var" name="ATM-missense-var"/>
<artifact id="Observation/ATR-insertion-molc" key="Observation-ATR-insertion-molc" name="ATR-insertion-molc"/>
<artifact id="Observation/ATR-insertion-significance" key="Observation-ATR-insertion-significance" name="ATR-insertion-significance"/>
<artifact id="Observation/ATR-insertion-var" key="Observation-ATR-insertion-var" name="ATR-insertion-var"/>
<artifact id="StructureDefinition/annotation-code" key="StructureDefinition-annotation-code" name="Annotation Code"/>
<artifact id="Observation/AnnotationExample" key="Observation-AnnotationExample" name="AnnotationExample"/>
<artifact deprecated="true" key="Feed" name="Bundle"/>
<artifact id="Patient/CGPatientExample01" key="Patient-CGPatientExample01" name="CGPatientExample01"/>
<artifact id="DocumentReference/CNVAnalysis-called" key="DocumentReference-CNVAnalysis-called" name="CNVAnalysis-called"/>
<artifact id="CodeSystem/clinvar-evidence-level-custom-cs" key="CodeSystem-clinvar-evidence-level-custom-cs" name="ClinVar Evidence Level Example Codes"/>
<artifact id="StructureDefinition/coded-annotation" key="StructureDefinition-coded-annotation" name="Coded Annotation"/>
<artifact id="CodeSystem/coded-annotation-types-cs" key="CodeSystem-coded-annotation-types-cs" name="Coded Annotation Type Codes"/>
<artifact id="ValueSet/coded-annotation-types-vs" key="ValueSet-coded-annotation-types-vs" name="Coded Annotation Types"/>
<artifact deprecated="true" id="CodeSystem/ConditionInheritanceMode" key="CodeSystem-ConditionInheritanceMode" name="Condition Inheritance Pattern"/>
<artifact deprecated="true" id="CodeSystem/ConditionInheritanceModeCS" key="CodeSystem-ConditionInheritanceModeCS" name="Condition Inheritance Pattern Codes"/>
<artifact id="ValueSet/condition-inheritance-mode-vs" key="ValueSet-condition-inheritance-vs" name="Condition Inheritance Patterns"/>
<artifact id="ValueSet/dna-change-type-vs" key="ValueSet-dna-change-type" name="DNA Change Type"/>
<artifact id="ConceptMap/dna-change-type-map" key="ConceptMap-dna-change-type-map" name="DNA Change Type Map"/>
<artifact id="StructureDefinition/diagnostic-implication" key="StructureDefinition-diagnostic-implication" name="Diagnostic Implication"/>
<artifact deprecated="true" key="DiagnosticReport" name="DiagnosticReport"/>
<artifact id="Observation/EGFR-L858R-molc" key="Observation-EGFR-L858R-molc" name="EGFR-L858R-molc"/>
<artifact id="Observation/EGFR-L858R-significance" key="Observation-EGFR-L858R-significance" name="EGFR-L858R-significance"/>
<artifact id="Observation/EGFR-L858R-therapuDrug1" key="Observation-EGFR-L858R-therapuDrug1" name="EGFR-L858R-therapuDrug1"/>
<artifact id="Observation/EGFR-L858R-therapuDrug2" key="Observation-EGFR-L858R-therapuDrug2" name="EGFR-L858R-therapuDrug2"/>
<artifact id="Observation/EGFR-L858R-var" key="Observation-EGFR-L858R-var" name="EGFR-L858R-var"/>
<artifact id="ValueSet/evidence-level-example-vs" key="ValueSet-evidence-level-example-vs" name="Evidence Level Examples"/>
<artifact deprecated="true" id="Task/TaskMedChgExample1" key="Task-TaskMedChgExample1" name="Example - TaskMedChg"/>
<artifact id="Observation/ExampleGermlineCNV" key="Observation-ExampleGermlineCNV" name="ExampleGermlineCNV"/>
<artifact id="Observation/ExampleGermlineDEL" key="Observation-ExampleGermlineDEL" name="ExampleGermlineDEL"/>
<artifact id="Observation/ExampleGermlineINV" key="Observation-ExampleGermlineINV" name="ExampleGermlineINV"/>
<artifact id="Organization/ExampleLab" key="Organization-ExampleLab" name="ExampleLab"/>
<artifact id="Organization/ExampleOrg" key="Organization-ExampleOrg" name="ExampleOrg"/>
<artifact id="Patient/ExamplePatient" key="Patient-ExamplePatient" name="ExamplePatient"/>
<artifact id="ServiceRequest/ExampleServiceRequest" key="ServiceRequest-ExampleServiceRequest" name="ExampleServiceRequest"/>
<artifact id="Observation/ExampleSomaticCNV" key="Observation-ExampleSomaticCNV" name="ExampleSomaticCNV"/>
<artifact id="Observation/ExampleSomaticDEL" key="Observation-ExampleSomaticDEL" name="ExampleSomaticDEL"/>
<artifact id="Observation/ExampleSomaticINV" key="Observation-ExampleSomaticINV" name="ExampleSomaticINV"/>
<artifact id="Specimen/ExampleSpecimen" key="Specimen-ExampleSpecimen" name="ExampleSpecimen"/>
<artifact id="OperationDefinition/find-population-dx-implications" key="OperationDefinition-find-population-dx-implications" name="Find Population Diagnostic Implications"/>
<artifact id="OperationDefinition/find-population-molecular-consequences" key="OperationDefinition-find-population-molecular-consequences" name="Find Population Molecular Consequences"/>
<artifact id="OperationDefinition/find-population-specific-haplotypes" key="OperationDefinition-find-population-specific-haplotypes" name="Find Population Specific Haplotypes"/>
<artifact id="OperationDefinition/find-population-specific-variants" key="OperationDefinition-find-population-specific-variants" name="Find Population Specific Variants"/>
<artifact id="OperationDefinition/find-population-structural-intersecting-variants" key="OperationDefinition-find-population-structural-intersecting-variants" name="Find Population Structural Intersecting Variants"/>
<artifact id="OperationDefinition/find-population-structural-subsuming-variants" key="OperationDefinition-find-population-structural-subsuming-variants" name="Find Population Structural Subsuming Variants"/>
<artifact id="OperationDefinition/find-population-tx-implications" key="OperationDefinition-find-population-tx-implications" name="Find Population Treatment Implications"/>
<artifact id="OperationDefinition/find-study-metadata" key="OperationDefinition-find-study-metadata" name="Find Study Metadata"/>
<artifact id="OperationDefinition/find-subject-dx-implications" key="OperationDefinition-find-subject-dx-implications" name="Find Subject Diagnostic Implications"/>
<artifact id="OperationDefinition/find-subject-haplotypes" key="OperationDefinition-find-subject-haplotypes" name="Find Subject Haplotypes"/>
<artifact id="OperationDefinition/find-subject-molecular-consequences" key="OperationDefinition-find-subject-molecular-consequences" name="Find Subject Molecular Consequences"/>
<artifact id="OperationDefinition/find-subject-specific-haplotypes" key="OperationDefinition-find-subject-specific-haplotypes" name="Find Subject Specific Haplotypes"/>
<artifact id="OperationDefinition/find-subject-specific-variants" key="OperationDefinition-find-subject-specific-variants" name="Find Subject Specific Variants"/>
<artifact id="OperationDefinition/find-subject-structural-intersecting-variants" key="OperationDefinition-find-subject-structural-intersecting-variants" name="Find Subject Structural Intersecting Variants"/>
<artifact id="OperationDefinition/find-subject-structural-subsuming-variants" key="OperationDefinition-find-subject-structural-subsuming-variants" name="Find Subject Structural Subsuming Variants"/>
<artifact id="OperationDefinition/find-subject-tx-implications" key="OperationDefinition-find-subject-tx-implications" name="Find Subject Treatment Implications"/>
<artifact id="OperationDefinition/find-subject-variants" key="OperationDefinition-find-subject-variants" name="Find Subject Variants"/>
<artifact id="Parameters/FindALLPopulationSpecificVariantsOutput" key="Parameters-FindALLPopulationSpecificVariantsOutput" name="FindALLPopulationSpecificVariantsOutput"/>
<artifact id="Parameters/FindANYPopulationSpecificVariantsOutput" key="Parameters-FindANYPopulationSpecificVariantsOutput" name="FindANYPopulationSpecificVariantsOutput"/>
<artifact id="Parameters/FindPopulationDxImplicationsOutput" key="Parameters-FindPopulationDxImplicationsOutput" name="FindPopulationDxImplicationsOutput"/>
<artifact id="Parameters/FindPopulationMolecConseqOutput" key="Parameters-FindPopulationMolecConseqOutput" name="FindPopulationMolecConseqOutput"/>
<artifact id="Parameters/FindPopulationSpecificHaplotypesOutput" key="Parameters-FindPopulationSpecificHaplotypesOutput" name="FindPopulationSpecificHaplotypesOutput"/>
<artifact id="Parameters/FindPopulationStructuralIntersectingVariantsOutput" key="Parameters-FindPopulationStructuralIntersectingVariantsOutput" name="FindPopulationStructuralIntersectingVariantsOutput"/>
<artifact id="Parameters/FindPopulationStructuralSubsumingVariantsOutput" key="Parameters-FindPopulationStructuralSubsumingVariantsOutput" name="FindPopulationStructuralSubsumingVariantsOutput"/>
<artifact id="Parameters/FindPopulationTxImplicationsOutput" key="Parameters-FindPopulationTxImplicationsOutput" name="FindPopulationTxImplicationsOutput"/>
<artifact id="Parameters/FindStudyMetadataOutput" key="Parameters-FindStudyMetadataOutput" name="FindStudyMetadataOutput"/>
<artifact id="Parameters/FindSubjectDxImplicationsOutput" key="Parameters-FindSubjectDxImplicationsOutput" name="FindSubjectDxImplicationsOutput"/>
<artifact id="Parameters/FindSubjectHaplotypesOutput" key="Parameters-FindSubjectHaplotypesOutput" name="FindSubjectHaplotypesOutput"/>
<artifact id="Parameters/FindSubjectMolecConseqOutput" key="Parameters-FindSubjectMolecConseqOutput" name="FindSubjectMolecConseqOutput"/>
<artifact id="Parameters/FindSubjectSpecificHaplotypesOutput" key="Parameters-FindSubjectSpecificHaplotypesOutput" name="FindSubjectSpecificHaplotypesOutput"/>
<artifact id="Parameters/FindSubjectSpecificVariantsOutput" key="Parameters-FindSubjectSpecificVariantsOutput" name="FindSubjectSpecificVariantsOutput"/>
<artifact id="Parameters/FindSubjectStructuralIntersectingVariantsOutput" key="Parameters-FindSubjectStructuralIntersectingVariantsOutput" name="FindSubjectStructuralIntersectingVariantsOutput"/>
<artifact id="Parameters/FindSubjectStructuralSubsumingVariantsOutput" key="Parameters-FindSubjectStructuralSubsumingVariantsOutput" name="FindSubjectStructuralSubsumingVariantsOutput"/>
<artifact id="Parameters/FindSubjectTxImplicationsOutput" key="Parameters-FindSubjectTxImplicationsOutput" name="FindSubjectTxImplicationsOutput"/>
<artifact id="Parameters/FindSubjectVariantsOutput" key="Parameters-FindSubjectVariantsOutput" name="FindSubjectVariantsOutput"/>
<artifact id="StructureDefinition/followup-recommendation" key="StructureDefinition-task-rec-followup" name="Followup Recommendation"/>
<artifact id="DocumentReference/FullGenome-GRCh38" key="DocumentReference-FullGenome-GRCh38" name="FullGenome-GRCh38"/>
<artifact id="ValueSet/functional-effect-vs" key="ValueSet-functional-effect" name="Functional Effect Value Set"/>
<artifact id="RiskAssessment/GenRiskDiabetesT2" key="RiskAssessment-GenRiskDiabetesT2" name="GenRiskDiabetesT2"/>
<artifact id="ValueSet/genetic-therapeutic-implications-vs" key="ValueSet-genetic-therapeutic-implications-vs" name="Genetic Therapeutic Implications"/>
<artifact id="StructureDefinition/genomic-base" key="StructureDefinition-genomic-base" name="Genomic Base"/>
<artifact id="StructureDefinition/genomic-data-file" key="StructureDefinition-genomic-data-file" name="Genomic Data File"/>
<artifact id="StructureDefinition/finding" key="StructureDefinition-finding" name="Genomic Finding"/>
<artifact id="StructureDefinition/implication" key="StructureDefinition-implication" name="Genomic Implication"/>
<artifact id="StructureDefinition/genomic-report" key="StructureDefinition-genomic-report" name="Genomic Report"/>
<artifact id="StructureDefinition/genomic-report-note" key="StructureDefinition-genomic-report-note" name="Genomic Report Note"/>
<artifact id="StructureDefinition/genomic-risk-assessment" key="StructureDefinition-genomic-risk-assessment" name="Genomic Risk Assessment"/>
<artifact id="StructureDefinition/genomic-study" key="StructureDefinition-genomic-study" name="Genomic Study"/>
<artifact id="StructureDefinition/genomic-study-analysis" key="StructureDefinition-genomic-study-analysis" name="Genomic Study Analysis"/>
<artifact id="StructureDefinition/genomic-study-analysis-change-type" key="StructureDefinition-genomic-study-analysis-change-type" name="Genomic Study Analysis Change Type"/>
<artifact id="StructureDefinition/genomic-study-analysis-device" key="StructureDefinition-genomic-study-analysis-device" name="Genomic Study Analysis Device"/>
<artifact id="StructureDefinition/genomic-study-analysis-ext" key="StructureDefinition-genomic-study-analysis-ext" name="Genomic Study Analysis Extension"/>
<artifact id="StructureDefinition/genomic-study-analysis-focus" key="StructureDefinition-genomic-study-analysis-focus" name="Genomic Study Analysis Focus"/>
<artifact id="StructureDefinition/genomic-study-analysis-genome-build" key="StructureDefinition-genomic-study-analysis-genome-build" name="Genomic Study Analysis Genome Build"/>
<artifact id="StructureDefinition/genomic-study-analysis-input" key="StructureDefinition-genomic-study-analysis-input" name="Genomic Study Analysis Input"/>
<artifact id="StructureDefinition/genomic-study-analysis-method-type" key="StructureDefinition-genomic-study-analysis-method-type" name="Genomic Study Analysis Method Type"/>
<artifact id="StructureDefinition/genomic-study-analysis-metrics" key="StructureDefinition-genomic-study-analysis-metrics" name="Genomic Study Analysis Metrics"/>
<artifact id="StructureDefinition/genomic-study-analysis-output" key="StructureDefinition-genomic-study-analysis-output" name="Genomic Study Analysis Output"/>
<artifact id="StructureDefinition/genomic-study-analysis-protocol-performed" key="StructureDefinition-genomic-study-analysis-protocol-performed" name="Genomic Study Analysis Protocol Performed"/>
<artifact id="StructureDefinition/genomic-study-analysis-regions" key="StructureDefinition-genomic-study-analysis-regions" name="Genomic Study Analysis Regions"/>
<artifact id="StructureDefinition/genomic-study-analysis-genomic-source-class" key="StructureDefinition-genomic-study-analysis-genomic-source-class" name="Genomic Study Analysis Source Class"/>
<artifact id="StructureDefinition/genomic-study-analysis-specimen" key="StructureDefinition-genomic-study-analysis-specimen" name="Genomic Study Analysis Specimen"/>
<artifact id="StructureDefinition/genomic-study-analysis-title" key="StructureDefinition-genomic-study-analysis-title" name="Genomic Study Analysis Title"/>
<artifact id="CodeSystem/genomic-study-change-type-cs" key="CodeSystem-genomic-study-change-type-cs" name="Genomic Study Change Type CodeSystem"/>
<artifact id="ValueSet/genomic-study-change-type-vs" key="ValueSet-genomic-study-change-type-vs" name="Genomic Study Change Type ValueSet"/>
<artifact id="CodeSystem/genomic-study-data-format-cs" key="CodeSystem-genomic-study-data-format-cs" name="Genomic Study Data Format CodeSystem"/>
<artifact id="ValueSet/genomic-study-data-format-vs" key="ValueSet-genomic-study-data-format-vs" name="Genomic Study Data Format ValueSet"/>
<artifact id="CodeSystem/genomic-study-method-type-cs" key="CodeSystem-genomic-study-method-type-cs" name="Genomic Study Method Type CodeSystem"/>
<artifact id="ValueSet/genomic-study-method-type-vs" key="ValueSet-genomic-study-method-type-vs" name="Genomic Study Method Type ValueSet"/>
<artifact id="StructureDefinition/genomic-study-reference" key="StructureDefinition-genomic-study-reference" name="Genomic Study Reference"/>
<artifact id="StructureDefinition/genomic-study-referrer-ext" key="StructureDefinition-genomic-study-referrer-ext" name="Genomic Study Referrer Extension"/>
<artifact id="CodeSystem/genomic-study-status-cs" key="CodeSystem-genomic-study-status-cs" name="Genomic Study Status CodeSystem"/>
<artifact id="ConceptMap/GenomicStudyStatusMap" key="ConceptMap-GenomicStudyStatusMap" name="Genomic Study Status Map"/>
<artifact id="ValueSet/genomic-study-status-vs" key="ValueSet-genomic-study-status-vs" name="Genomic Study Status ValueSet"/>
<artifact id="CodeSystem/genomic-study-type-cs" key="CodeSystem-genomic-study-type-cs" name="Genomic Study Type CodeSystem"/>
<artifact id="ValueSet/genomic-study-type-vs" key="ValueSet-genomic-study-type-vs" name="Genomic Study Type ValueSet"/>
<artifact id="DiagnosticReport/GenomicReportExample01" key="DiagnosticReport-GenomicReportExample01" name="GenomicReportExample01"/>
<artifact id="ServiceRequest/GenomicServiceRequestExample01" key="ServiceRequest-GenomicServiceRequestExample01" name="GenomicServiceRequestExample01"/>
<artifact id="Specimen/GenomicSpecimenExample01" key="Specimen-GenomicSpecimenExample01" name="GenomicSpecimenExample01"/>
<artifact id="Specimen/GenomicSpecimenExample02" key="Specimen-GenomicSpecimenExample02" name="GenomicSpecimenExample02"/>
<artifact deprecated="true" id="StructureDefinition/genomics-artifact" key="StructureDefinition-genomics-artifact" name="Genomics Artifact"/>
<artifact deprecated="true" id="StructureDefinition/genomics-base" key="StructureDefinition-genomics-base" name="Genomics Base"/>
<artifact deprecated="true" id="StructureDefinition/genomics-document-reference" key="StructureDefinition-genomics-document-reference" name="Genomics DocumentReference"/>
<artifact deprecated="true" id="StructureDefinition/genomics-file" key="StructureDefinition-genomics-file" name="Genomics File"/>
<artifact deprecated="true" id="StructureDefinition/genomics-report" key="StructureDefinition-genomics-report" name="Genomics Report"/>
<artifact deprecated="true" id="StructureDefinition/genomics-risk-assessment" key="StructureDefinition-diagnosticReport-risk" name="Genomics Risk Assessment"/>
<artifact deprecated="true" id="StructureDefinition/servicerequest" key="StructureDefinition-servicerequest" name="Genomics Service Request"/>
<artifact deprecated="true" id="StructureDefinition/specimen" key="StructureDefinition-specimen" name="Genomics Specimen"/>
<artifact deprecated="true" id="DiagnosticReport/GenomicsReportExample01" key="DiagnosticReport-GenomicsReportExample01" name="GenomicsReportExample01"/>
<artifact deprecated="true" id="ServiceRequest/GenomicsServiceRequestExample01" key="ServiceRequest-GenomicsServiceRequestExample01" name="GenomicsServiceRequestExample01"/>
<artifact id="StructureDefinition/genotype" key="StructureDefinition-genotype" name="Genotype"/>
<artifact id="Observation/Genotype-Clinical-Trial-Example-using-haplotypes" key="Observation-Genotype-Clinical-Trial-Example-using-haplotypes" name="Genotype-Clinical-Trial-Example-using-haplotypes"/>
<artifact id="Observation/GenotypeExample1" key="Observation-GenotypeExample1" name="GenotypeExample1"/>
<artifact id="Observation/GenotypeExamplePharmVar" key="Observation-GenotypeExamplePharmVar" name="GenotypeExamplePharmVar"/>
<artifact deprecated="true" id="StructureDefinition/grouper" key="StructureDefinition-grouper" name="Grouper"/>
<artifact id="Observation/GrouperEx01" key="Observation-GrouperEx01" name="GrouperEx01"/>
<artifact id="Observation/GrouperEx02" key="Observation-GrouperEx02" name="GrouperEx02"/>
<artifact id="Observation/GrouperEx03" key="Observation-GrouperEx03" name="GrouperEx03"/>
<artifact id="Observation/HER2byImmuneStainExample" key="Observation-HER2byImmuneStainExample" name="HER2byImmuneStainExample"/>
<artifact id="Observation/HER2byImmunoassayExample" key="Observation-HER2byImmunoassayExample" name="HER2byImmunoassayExample"/>
<artifact id="Patient/HG00403" key="Patient-HG00403" name="HG00403"/>
<artifact id="Observation/HLA-A-haplotype1" key="Observation-HLA-A-haplotype1" name="HLA-A-haplotype1"/>
<artifact id="Observation/HLA-A-haplotype2" key="Observation-HLA-A-haplotype2" name="HLA-A-haplotype2"/>
<artifact id="Observation/HLA-B-haplotype1" key="Observation-HLA-B-haplotype1" name="HLA-B-haplotype1"/>
<artifact id="Observation/HLA-B-haplotype2" key="Observation-HLA-B-haplotype2" name="HLA-B-haplotype2"/>
<artifact id="Observation/HLA-C-haplotype1" key="Observation-HLA-C-haplotype1" name="HLA-C-haplotype1"/>
<artifact id="Observation/HLA-C-haplotype2" key="Observation-HLA-C-haplotype2" name="HLA-C-haplotype2"/>
<artifact id="ValueSet/hgnc-vs" key="ValueSet-hgnc" name="HUGO Gene Nomenclature Committee Gene Names (HGNC)"/>
<artifact id="StructureDefinition/haplotype" key="StructureDefinition-haplotype" name="Haplotype"/>
<artifact id="Observation/HaplotypeExamplePharmVar01" key="Observation-HaplotypeExamplePharmVar01" name="HaplotypeExamplePharmVar01"/>
<artifact id="Observation/HaplotypeExamplePharmVar02" key="Observation-HaplotypeExamplePharmVar02" name="HaplotypeExamplePharmVar02"/>
<artifact id="Observation/HaplotypeSet-Clinical-Trial-Example-1of2" key="Observation-HaplotypeSet-Clinical-Trial-Example-1of2" name="HaplotypeSet-Clinical-Trial-Example-1of2"/>
<artifact id="Observation/HaplotypeSet-Clinical-Trial-Example-2of2" key="Observation-HaplotypeSet-Clinical-Trial-Example-2of2" name="HaplotypeSet-Clinical-Trial-Example-2of2"/>
<artifact deprecated="true" id="ValueSet/high-low-codes-vs" key="ValueSet-high-low-codes" name="High Low codes"/>
<artifact id="ValueSet/hgvs-vs" key="ValueSet-hgvs" name="Human Genome Variation Society (HGVS) Nomenclature"/>
<artifact id="Observation/ISCN-CMLExample" key="Observation-ISCN-CMLExample" name="ISCN-CMLExample"/>
<artifact id="Observation/ISCN-CMLImplication" key="Observation-ISCN-CMLImplication" name="ISCN-CMLImplication"/>
<artifact id="Observation/ISCN-NormalExample" key="Observation-ISCN-NormalExample" name="ISCN-NormalExample"/>
<artifact deprecated="true" key="ImplementationGuide" name="ImplementationGuide"/>
<artifact id="Observation/MSH2-del-disease" key="Observation-MSH2-del-disease" name="MSH2-del-disease"/>
<artifact id="Observation/MSH2-del-molc" key="Observation-MSH2-del-molc" name="MSH2-del-molc"/>
<artifact id="Observation/MSH2-del-var" key="Observation-MSH2-del-var" name="MSH2-del-var"/>
<artifact id="Observation/MSIExample" key="Observation-MSIExample" name="MSIExample"/>
<artifact deprecated="true" id="StructureDefinition/medication-assessed" key="StructureDefinition-medication-assessed" name="Medication Assessed"/>
<artifact id="StructureDefinition/medication-assessed-reference" key="StructureDefinition-medication-assessed-reference" name="Medication Assessed reference to a FHIR resource"/>
<artifact id="StructureDefinition/medication-recommendation" key="StructureDefinition-medication-recommendation" name="Medication Recommendation"/>
<artifact id="Task/MedicationRecommendationExample1" key="StructureDefinition-task-med-chg" name="MedicationRecommendationExample1"/>
<artifact id="MedicationStatement/MedicationStatementWarfarin" key="MedicationStatement-MedicationStatementWarfarin" name="MedicationStatementWarfarin"/>
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<artifact deprecated="true" key="Sequence" name="MolecularSequence"/>
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<artifact deprecated="true" key="Observation" name="Observation"/>
<artifact deprecated="true" id="StructureDefinition/overall-interpretation" key="StructureDefinition-overall-interpretation" name="Overall Interpretation"/>
<artifact deprecated="true" id="Observation/OverallInterpExample1" key="Observation-OverallInterpExample1" name="OverallInterpExample1"/>
<artifact deprecated="true" id="Observation/OverallInterpExample2" key="Observation-OverallInterpExample2" name="OverallInterpExample2"/>
<artifact id="Observation/PDL1Example" key="Observation-PDL1Example" name="PDL1Example"/>
<artifact id="Procedure/PGXGenomicStudy" key="Procedure-PGXGenomicStudy" name="PGXGenomicStudy"/>
<artifact id="Procedure/PGXGenomicStudyAnalysis" key="Procedure-PGXGenomicStudyAnalysis" name="PGXGenomicStudyAnalysis"/>
<artifact id="DiagnosticReport/PGxGenomicReportEMERGE" key="DiagnosticReport-PGxGenomicReportEMERGE" name="PGxGenomicReportEMERGE"/>
<artifact id="DiagnosticReport/PGxGenomicReportEMERGE-withGrouping" key="DiagnosticReport-PGxGenomicReportEMERGE-withGrouping" name="PGxGenomicReportEMERGE-withGrouping"/>
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<artifact deprecated="true" id="DiagnosticReport/PGxGenomicsReportEMERGE-withGrouping" key="DiagnosticReport-PGxGenomicsReportEMERGE-withGrouping" name="PGxGenomicsReportEMERGE-withGrouping"/>
<artifact id="Task/PGxRecEx01" key="Task-PGxRecEx01" name="PGxRecEx01"/>
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<artifact id="Task/PGxRecEx04" key="Task-PGxRecEx04" name="PGxRecEx04"/>
<artifact id="Task/PGxRecEx05" key="Task-PGxRecEx05" name="PGxRecEx05"/>
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<artifact id="StructureDefinition/recommended-action" key="StructureDefinition-RecommendedAction" name="Recommended Action"/>
<artifact deprecated="true" id="StructureDefinition/region-studied" key="StructureDefinition-region-studied" name="Region Studied"/>
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<artifact deprecated="true" id="StructureDefinition/CGRelatedArtifact" key="StructureDefinition-CGRelatedArtifact" name="Related Artifact"/>
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<artifact id="Observation/SequencePhaseRelationExample1" key="Observation-SequencePhaseRelationExample1" name="SequencePhaseRelationExample1"/>
<artifact id="Procedure/SequencingProcedure" key="Procedure-SequencingProcedure" name="SequencingProcedure"/>
<artifact id="DocumentReference/SimpleVariantAnalysis-called" key="DocumentReference-SimpleVariantAnalysis-called" name="SimpleVariantAnalysis-called"/>
<artifact deprecated="true" id="StructureDefinition/supporting-information" key="StructureDefinition-SupportingInfo" name="Supporting Information"/>
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<artifact id="Observation/TMBExample" key="Observation-TMBExample" name="TMBExample"/>
<artifact deprecated="true" key="Task" name="Task"/>
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<artifact id="CodeSystem/tbd-codes-cs" key="CodeSystem-TbdCodes" name="To Be Determined Codes"/>
<artifact id="ValueSet/tbd-codes-vs" key="ValueSet-tbd" name="To Be Determined Value Set"/>
<artifact deprecated="true" id="StructureDefinition/tmb" key="StructureDefinition-tmb" name="Tumor Mutation Burden"/>
<artifact id="Observation/TumorMutationBurdenExample01" key="Observation-TumorMutationBurdenExample01" name="TumorMutationBurdenExample01"/>
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<artifact deprecated="true" id="ValueSet/variant-inheritance-vs" key="ValueSet-variant-inheritance" name="Variant Inheritances"/>
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<artifact id="Observation/VariantExample" key="Observation-VariantExample" name="VariantExample"/>
<artifact id="Observation/VariantExample1" key="Observation-VariantExample1" name="VariantExample1"/>
<artifact id="Observation/VariantExample2" key="Observation-VariantExample2" name="VariantExample2"/>
<artifact id="DocumentReference/WES-FullSequencedRegion-GRCh38" key="DocumentReference-WES-FullSequencedRegion-GRCh38" name="WES-FullSequencedRegion-GRCh38"/>
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<artifact id="Observation/ZFHX3-uncertain-var" key="Observation-ZFHX3-uncertain-var" name="ZFHX3-uncertain-var"/>
<artifact id="Procedure/analysisTumorNormalDNA" key="Procedure-analysisTumorNormalDNA" name="analysisTumorNormalDNA"/>
<artifact id="Procedure/analysisTumorRNA" key="Procedure-analysisTumorRNA" name="analysisTumorRNA"/>
<artifact id="Bundle/bundle-CG-IG-HLA-FullBundle-01" key="Bundle-CG-IG-HLA-FullBundle-01" name="bundle-CG-IG-HLA-FullBundle-01"/>
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<artifact id="Bundle/bundle-cgexample" key="Bundle-diagnosticreport-cgexample" name="bundle-cgexample"/>
<artifact id="Bundle/bundle-cgexample-withGrouping" key="Bundle-bundle-cgexample-withGrouping" name="bundle-cgexample-withGrouping"/>
<artifact id="Bundle/bundle-complexVariant-nonHGVS" key="Bundle-complexVariant-nonHGVS" name="bundle-complexVariant-nonHGVS"/>
<artifact id="Bundle/bundle-compound-heterozygote" key="Bundle-compound-heterozygote" name="bundle-compound-heterozygote"/>
<artifact id="Bundle/bundle-oncology-diagnostic" key="Bundle-oncology-diagnostic" name="bundle-oncology-diagnostic"/>
<artifact id="Bundle/bundle-oncology-report-example" key="Bundle-oncology-report-example" name="bundle-oncology-report-example"/>
<artifact id="Bundle/bundle-oncologyexamples-r4" key="Bundle-oncologyexamples-r4" name="bundle-oncologyexamples-r4"/>
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<artifact id="Bundle/bundle-pgxexample" key="Bundle-diagnosticreport-pgxexample" name="bundle-pgxexample"/>
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<artifact id="Patient/denovoChild" key="Patient-denovoChild" name="denovoChild"/>
<artifact id="Patient/denovoFather" key="Patient-denovoFather" name="denovoFather"/>
<artifact id="Patient/denovoMother" key="Patient-denovoMother" name="denovoMother"/>
<artifact id="Observation/diagnosticImplication-interact-smn1-smn2" key="Observation-diagnosticImplication-interact-smn1-smn2" name="diagnosticImplication-interact-smn1-smn2"/>
<artifact id="DiagnosticReport/diagnosticreport-hla-glstring-r4" key="DiagnosticReport-diagnosticreport-hla-glstring-r4" name="diagnosticreport-hla-glstring-r4"/>
<artifact id="ServiceRequest/eMERGEServiceRequest" key="ServiceRequest-eMERGEServiceRequest" name="eMERGEServiceRequest"/>
<artifact id="DocumentReference/genomicFileFatherBAM" key="DocumentReference-genomicFileFatherBAM" name="genomicFileFatherBAM"/>
<artifact id="DocumentReference/genomicFileMotherBAM" key="DocumentReference-genomicFileMotherBAM" name="genomicFileMotherBAM"/>
<artifact id="DocumentReference/genomicFileProbandBAM" key="DocumentReference-genomicFileProbandBAM" name="genomicFileProbandBAM"/>
<artifact id="DocumentReference/genomicFileProbandVCF" key="DocumentReference-genomicFileProbandVCF" name="genomicFileProbandVCF"/>
<artifact id="Patient/genomicPatient" key="Patient-genomicPatient" name="genomicPatient"/>
<artifact id="ServiceRequest/genomicServiceRequest" key="ServiceRequest-genomicServiceRequest" name="genomicServiceRequest"/>
<artifact id="Specimen/genomicSpecimen" key="Specimen-genomicSpecimen" name="genomicSpecimen"/>
<artifact id="DocumentReference/genomicVCFfile-cnv" key="DocumentReference-genomicVCFfile-cnv" name="genomicVCFfile-cnv"/>
<artifact id="DocumentReference/genomicVCFfile-simple" key="DocumentReference-genomicVCFfile-simple" name="genomicVCFfile-simple"/>
<artifact id="Procedure/genomicstudy-trio2" key="Procedure-genomicstudy-trio2" name="genomicstudy-trio2"/>
<artifact id="Procedure/genomicstudyanalysis-trio2" key="Procedure-genomicstudyanalysis-trio2" name="genomicstudyanalysis-trio2"/>
<artifact id="Observation/genotype-hla-a-glstring-r4" key="Observation-genotype-hla-a-glstring-r4" name="genotype-hla-a-glstring-r4"/>
<artifact id="Observation/haplotype-hla-a-1-r4" key="Observation-haplotype-hla-a-1-r4" name="haplotype-hla-a-1-r4"/>
<artifact id="Procedure/lungMass" key="Procedure-lungMass" name="lungMass"/>
<artifact id="Procedure/lungMass-analysis1" key="Procedure-lungMass-analysis1" name="lungMass-analysis1"/>
<artifact id="Procedure/lungMass-analysis2" key="Procedure-lungMass-analysis2" name="lungMass-analysis2"/>
<artifact id="Observation/molec-conseq1" key="Observation-molec-conseq1" name="molec-conseq1"/>
<artifact id="Observation/molec-conseq2" key="Observation-molec-conseq2" name="molec-conseq2"/>
<artifact id="Observation/molec-conseq3" key="Observation-molec-conseq3" name="molec-conseq3"/>
<artifact id="Observation/molec-conseq4" key="Observation-molec-conseq4" name="molec-conseq4"/>
<artifact id="Specimen/normalSpecimen" key="Specimen-normalSpecimen" name="normalSpecimen"/>
<artifact id="Observation/obs-idh-ex" key="Observation-obs-idh-ex" name="obs-idh-ex"/>
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<artifact id="Practitioner/orderingPractitioner" key="Practitioner-orderingPractitioner" name="orderingPractitioner"/>
<artifact deprecated="true" id="Observation/overallInt" key="Observation-overallInt" name="overallInt"/>
<artifact id="Practitioner/pathologistPractitioner" key="Practitioner-pathologistPractitioner" name="pathologistPractitioner"/>
<artifact id="Organization/performingOrganization" key="Organization-performingOrganization" name="performingOrganization"/>
<artifact id="Practitioner/practitioner02" key="Practitioner-practitioner02" name="practitioner02"/>
<artifact id="ServiceRequest/servicerequest-hla-a-r4" key="ServiceRequest-servicerequest-hla-a-r4" name="servicerequest-hla-a-r4"/>
<artifact id="Patient/somaticPatient" key="Patient-somaticPatient" name="somaticPatient"/>
<artifact id="DiagnosticReport/somaticReport" key="DiagnosticReport-somaticReport" name="somaticReport"/>
<artifact id="ServiceRequest/somaticServiceRequest" key="ServiceRequest-somaticServiceRequest" name="somaticServiceRequest"/>
<artifact id="Procedure/somaticStudy" key="Procedure-somaticStudy" name="somaticStudy"/>
<artifact id="DocumentReference/somaticVCFfile" key="DocumentReference-somaticVCFfile" name="somaticVCFfile"/>
<artifact id="Specimen/specimen-hla-r4" key="Specimen-specimen-hla-r4" name="specimen-hla-r4"/>
<artifact id="Practitioner/supervisorPractitioner" key="Practitioner-supervisorPractitioner" name="supervisorPractitioner"/>
<artifact id="Observation/therapuDrug1-interact-smn1-smn2" key="Observation-therapuDrug1-interact-smn1-smn2" name="therapuDrug1-interact-smn1-smn2"/>
<artifact id="Observation/therapuDrug2-interact-smn1-smn2" key="Observation-therapuDrug2-interact-smn1-smn2" name="therapuDrug2-interact-smn1-smn2"/>
<artifact id="Observation/therapuDrug3-interact-smn1-smn2" key="Observation-therapuDrug3-interact-smn1-smn2" name="therapuDrug3-interact-smn1-smn2"/>
<artifact id="Device/triodenovo-software" key="Device-triodenovo-software" name="triodenovo-software"/>
<artifact id="Specimen/tumorSpecimen" key="Specimen-tumorSpecimen" name="tumorSpecimen"/>
<artifact id="Observation/variant-with-molec-consequences" key="Observation-variant-with-molec-consequences" name="variant-with-molec-consequences"/>
<page key="NA" name="(NA)"/>
<page key="many" name="(many)"/>
<page deprecated="true" key="profiles" name="(profiles)"/>
<page key="v2" name="Appendix A: Relation to v2 reporting"/>
<page key="cgapps" name="Appendix B: Clinical Genomic Apps"/>
<page key="domain" name="Appendix C: HL7 Domain Analysis Model"/>
<page key="usecases" name="Appendix D: Query Guidance"/>
<page key="codings" name="Appendix E: External Coding Systems"/>
<page key="conversion" name="Appendix F: Conversion from FHIR Core STU3"/>
<page key="molecularSequence" name="Appendix G: Molecular Sequence"/>
<page key="groupingGuidance" name="Appendix H: Grouping Guidance"/>
<page key="Glossary" name="Appendix I: Glossary"/>
<page key="artifacts" name="Artifacts Summary"/>
<page key="changes" name="Change Log"/>
<page key="general" name="General Genomic Reporting"/>
<page key="background" name="Genomic Background"/>
<page key="operations" name="Genomic Operations"/>
<page key="histocompatibility" name="Histocompatibility and Immunogenetic Reporting"/>
<page key="index" name="Home Page"/>
<page key="pharmacogenomics" name="Pharmacogenomic Reporting"/>
<page key="somatics" name="Somatic Reporting"/>
<page key="toc" name="Table of Contents"/>
<page key="downloads" name="Useful Downloads"/>
<page key="sequencing" name="Variant Reporting"/>
<page deprecated="true" key="documentation" name="documentation"/>
<page deprecated="true" key="genomics" name="genomics"/>
</specification>