diff --git a/__tests__/helpers/arrayToRegex.ts b/__tests__/helpers/arrayToRegex.ts
new file mode 100644
index 0000000..7fcd3b9
--- /dev/null
+++ b/__tests__/helpers/arrayToRegex.ts
@@ -0,0 +1,15 @@
+import arrayToRegex from '../../lib/helpers/arrayToRegex';
+
+describe('arrayToRegex', () => {
+  it('should return null on empty array', () => {
+    expect(arrayToRegex([])).toBeNull();
+  });
+
+  it('should sort by length', () => {
+    expect(arrayToRegex(['bb', 'ccc', 'a'])).toStrictEqual(/(ccc)|(bb)|(a)/g);
+  });
+
+  it('should add a specific modifier', () => {
+    expect(arrayToRegex(['bb', 'a', 'ccc'], (a) => `--${a}`)).toStrictEqual(/(--ccc)|(--bb)|(--a)/g);
+  });
+});
diff --git a/__tests__/replace.css.ts b/__tests__/replace.css.ts
index 6a80789..e86b767 100644
--- a/__tests__/replace.css.ts
+++ b/__tests__/replace.css.ts
@@ -588,38 +588,6 @@ it('replace css variables in calc and multiple variables | rename-css-selectors#
   );
 });
 
-it('replace css variables with deep nested and multiline | rename-css-selectors#43', () => {
-  replaceCssMacro(
-    `
-      :root {
-        --top: 2px;
-        --right: 2px;
-        --left: 2px;
-      }
-
-      .my-selector {
-        margin: var(--top, var(--right))
-                var(--right, var(--top, 3px))
-                5px
-                var(--left, var(--top, var(--not-renamed, 5px)))
-      }
-    `,
-    `
-      :root {
-        --a: 2px;
-        --b: 2px;
-        --c: 2px;
-      }
-
-      .a {
-        margin: var(--a, var(--b))
-                var(--b, var(--a, 3px))
-                5px
-                var(--c, var(--a, var(--not-renamed, 5px)))
-      }
-    `,
-  );
-});
 
 it('should replace excluded special characters | rename-css-selectors#77', () => {
   rcs.selectorsLibrary.setExclude('somediv:test-me');
@@ -645,3 +613,34 @@ it('should classes with and ignore them | rcs-core#133', () => {
     '.a.bottom-\\[99999px\\][class="test"] {bottom: 99999px;}',
   );
 });
+
+it('replace multiple variables after each other | #137', () => {
+  replaceCssMacro(
+    `
+      *, ::before, ::after {
+        --tw-shadow: 0 0 transparent;
+        --tw-ring-offset-shadow: 0 0 transparent;
+        --tw-ring-shadow: 0 0 transparent;
+      }
+
+      .shadow-small {
+        --tw-shadow: 0 2px 4px 0 rgb(151, 145, 151, 0.1);
+        box-shadow: 0 0 transparent, 0 0 transparent, var(--tw-shadow);
+        box-shadow: var(--tw-ring-offset-shadow, 0 0 transparent), var(--tw-ring-shadow, 0 0 transparent), var(--tw-shadow);
+      }
+    `,
+    `
+      *, ::before, ::after {
+        --a: 0 0 transparent;
+        --b: 0 0 transparent;
+        --c: 0 0 transparent;
+      }
+
+      .a {
+        --a: 0 2px 4px 0 rgb(151, 145, 151, 0.1);
+        box-shadow: 0 0 transparent, 0 0 transparent, var(--a);
+        box-shadow: var(--b, 0 0 transparent), var(--c, 0 0 transparent), var(--a);
+      }
+    `,
+  );
+});
diff --git a/__tests__/selectorsLibrary.ts b/__tests__/selectorsLibrary.ts
index 731a060..731adf3 100644
--- a/__tests__/selectorsLibrary.ts
+++ b/__tests__/selectorsLibrary.ts
@@ -233,7 +233,7 @@ it('getall | should return a regex of compressed with classes', () => {
     addSelectorType: true,
   });
 
-  expect(regex.source).toBe('(\\#a)|(\\.a|\\.b)');
+  expect(regex.source).toBe('(\\.a|\\.b)|(\\#a)');
 });
 
 it('getall | should return an array with selectors', () => {
@@ -293,7 +293,7 @@ it('getall | should return a regex of non compressed with classes', () => {
     addSelectorType: true,
   });
 
-  expect(regex.source).toBe('(\\#id)|(\\.bottom-\\[9px]|\\.test)');
+  expect(regex.source).toBe('(\\.bottom-\\[9px]|\\.test)|(\\#id)');
 });
 
 it('getall | should return a regex of non compressed selecotrs', () => {
@@ -303,7 +303,7 @@ it('getall | should return a regex of non compressed selecotrs', () => {
     getRenamedValues: true,
   });
 
-  expect(regex.source).toBe('((\\s|\\#)(a)[\\s)])|((\\s|\\.)(a|b)[\\s)])');
+  expect(regex.source).toBe('((\\s|\\.)(a|b)[\\s)])|((\\s|\\#)(a)[\\s)])');
 });
 
 it('getall | should return a regex of compressed selectors', () => {
@@ -311,7 +311,7 @@ it('getall | should return a regex of compressed selectors', () => {
 
   const regex = rcs.selectorsLibrary.getAllRegex();
 
-  expect(regex.source).toBe('((\\s|\\#)(id)[\\s)])|((\\s|\\.)(bottom-\\[9px]|test)[\\s)])');
+  expect(regex.source).toBe('((\\s|\\.)(bottom-\\[9px]|test)[\\s)])|((\\s|\\#)(id)[\\s)])');
 });
 
 it('getall | should get all setted classes', () => {
diff --git a/lib/helpers/arrayToRegex.ts b/lib/helpers/arrayToRegex.ts
new file mode 100644
index 0000000..262be54
--- /dev/null
+++ b/lib/helpers/arrayToRegex.ts
@@ -0,0 +1,20 @@
+function arrayToRegex(
+  values: string[],
+  modifier: (value: string) => string = (value) => value,
+): RegExp | null {
+  if (!values.length) {
+    return null;
+  }
+
+  return (
+    new RegExp(`(${values
+      // sort by size
+      .sort((a, b) => b.length - a.length)
+      // add -- to ensure to only capture attributes
+      .map(modifier)
+      .join(')|(')
+    })`, 'g')
+  );
+}
+
+export default arrayToRegex;
diff --git a/lib/replace/css.ts b/lib/replace/css.ts
index 380af37..66074c8 100644
--- a/lib/replace/css.ts
+++ b/lib/replace/css.ts
@@ -1,36 +1,11 @@
 import { parse } from 'postcss';
 
 import cssVariablesLibrary from '../cssVariablesLibrary';
+import arrayToRegex from '../helpers/arrayToRegex';
 import keyframesLibrary from '../keyframesLibrary';
 import selectorsLibrary from '../selectorsLibrary';
 import replaceRegex from './regex';
 
-const extractCssVariables = (value: string): string[] => {
-  const regexMatches = value.match(new RegExp(replaceRegex.cssVariables));
-
-  let matches: string[] = [];
-
-  if (regexMatches) {
-    regexMatches.forEach((matchWithVariables) => {
-      const cssVariableMatch = new RegExp(replaceRegex.cssVariables).exec(matchWithVariables);
-
-      if (!cssVariableMatch) {
-        return;
-      }
-
-      matches = [...matches, cssVariableMatch[1]];
-
-      if (cssVariableMatch[2]) {
-        const innerMatches = extractCssVariables(cssVariableMatch[2]);
-
-        matches = [...matches, ...innerMatches];
-      }
-    });
-  }
-
-  return [...(new Set(matches))];
-};
-
 // calls the selectorLibrary.getAttributeSelector internally
 // String.replace will call this function and
 // get call selectorLibrary.getAttributeSelector directly
@@ -180,12 +155,14 @@ const replaceCss = (css: string | Buffer, opts: ReplaceCssOptions = {}): string
     * replace css variables var() *
     * *************************** */
     if (node.value.match(replaceRegex.cssVariables)) {
-      const matches = extractCssVariables(node.value);
+      const regex = arrayToRegex(Object.keys(cssVariablesLibrary.values), (v) => `--${v}`);
 
-      // eslint-disable-next-line no-param-reassign
-      node.value = node.value.replace(new RegExp(matches.join('|'), 'g'), (match: string) => (
-        cssVariablesLibrary.get(match, { source })
-      ));
+      if (regex) {
+        // eslint-disable-next-line no-param-reassign
+        node.value = node.value.replace(regex, (match: string) => (
+          `--${cssVariablesLibrary.get(match.replace(/^--/, ''), { source })}`
+        ));
+      }
     }
 
     /* ******************************************** *
diff --git a/lib/selectorsLibrary.ts b/lib/selectorsLibrary.ts
index d94da0d..774bad4 100644
--- a/lib/selectorsLibrary.ts
+++ b/lib/selectorsLibrary.ts
@@ -2,6 +2,7 @@ import { AttributeLibrary } from './attributeLibrary';
 import idSelectorLibrary, { IdSelectorLibrary } from './idSelectorLibrary';
 import classSelectorLibrary, { ClassSelectorLibrary } from './classSelectorLibrary';
 import { BaseLibrary, BaseLibraryOptions } from './baseLibrary';
+import arrayToRegex from './helpers/arrayToRegex';
 
 // Simple aggregate class to avoid duplicating code dealing with any CSS selector.
 export class SelectorsLibrary extends BaseLibrary {
@@ -127,7 +128,9 @@ export class SelectorsLibrary extends BaseLibrary {
 
     const ret = this.callOnBoth('getAll', options);
 
-    return new RegExp(`(${ret.filter(Boolean).map((x) => x.source).join(')|(')})`, 'g');
+    // null assertion to keep the same functionality
+    // eslint-disable-next-line @typescript-eslint/no-non-null-assertion
+    return arrayToRegex(ret.filter(Boolean).map((x) => x.source))!;
   }
 
   get(value: string, opts: BaseLibraryOptions = {}): string {