Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

multiple mutations at the same position(s) #81

Open
amelie-stein opened this issue May 24, 2023 · 0 comments
Open

multiple mutations at the same position(s) #81

amelie-stein opened this issue May 24, 2023 · 0 comments
Assignees

Comments

@amelie-stein
Copy link
Contributor

Starting from a pipeline mutfile with two mutations at the same positions, we only get output for the second.
Hypothesis: this is because the mutfile translator (from pipeline-style input to Rosetta-mutfile-style) uses only the position(s) for naming, but not the target amino acids.
Possible solutions:

  • pre-screen pipeline mutfile for variants that use the same positions, and merge those into a single (Rosetta) mutfile
  • include target AAs in mutfile name
Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

No branches or pull requests

2 participants