diff --git a/pkgs/development/python-modules/accelerate/default.nix b/pkgs/development/python-modules/accelerate/default.nix
index dd2f90f912e118..b05d6848768f53 100644
--- a/pkgs/development/python-modules/accelerate/default.nix
+++ b/pkgs/development/python-modules/accelerate/default.nix
@@ -61,14 +61,9 @@ buildPythonPackage rec {
     pytest7CheckHook
     transformers
   ];
-  preCheck =
-    ''
-      export HOME=$(mktemp -d)
-      export PATH=$out/bin:$PATH
-    ''
-    + lib.optionalString config.cudaSupport ''
-      export TRITON_PTXAS_PATH="${cudatoolkit}/bin/ptxas"
-    '';
+  preCheck = lib.optionalString config.cudaSupport ''
+    export TRITON_PTXAS_PATH="${cudatoolkit}/bin/ptxas"
+  '';
   pytestFlagsArray = [ "tests" ];
   disabledTests =
     [
diff --git a/pkgs/development/python-modules/aeppl/default.nix b/pkgs/development/python-modules/aeppl/default.nix
index 62067166d5df0a..ca4920126c5412 100644
--- a/pkgs/development/python-modules/aeppl/default.nix
+++ b/pkgs/development/python-modules/aeppl/default.nix
@@ -38,10 +38,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d);
-  '';
-
   pythonImportsCheck = [ "aeppl" ];
 
   disabledTests = [
diff --git a/pkgs/development/python-modules/afdko/default.nix b/pkgs/development/python-modules/afdko/default.nix
index 3181ecda763970..0a92ae2439e261 100644
--- a/pkgs/development/python-modules/afdko/default.nix
+++ b/pkgs/development/python-modules/afdko/default.nix
@@ -97,8 +97,6 @@ buildPythonPackage rec {
   nativeCheckInputs = [ pytestCheckHook ];
 
   preCheck = ''
-    export PATH=$PATH:$out/bin
-
     # Remove build artifacts to prevent them from messing with the tests
     rm -rf _skbuild
   '';
diff --git a/pkgs/development/python-modules/aiodhcpwatcher/default.nix b/pkgs/development/python-modules/aiodhcpwatcher/default.nix
index f7fde19dc644a7..16989e989305c7 100644
--- a/pkgs/development/python-modules/aiodhcpwatcher/default.nix
+++ b/pkgs/development/python-modules/aiodhcpwatcher/default.nix
@@ -39,10 +39,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   pythonImportsCheck = [ "aiodhcpwatcher" ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/aiogithubapi/default.nix b/pkgs/development/python-modules/aiogithubapi/default.nix
index 5f4a3c28d15469..6e0c9a5e65902b 100644
--- a/pkgs/development/python-modules/aiogithubapi/default.nix
+++ b/pkgs/development/python-modules/aiogithubapi/default.nix
@@ -56,8 +56,6 @@ buildPythonPackage rec {
   pytestFlagsArray = [ "--asyncio-mode=auto" ];
 
   preCheck = ''
-    export HOME=$(mktemp -d)
-
     # Need sigstore is an optional dependencies and need <2
     rm -rf tests/test_helper.py
   '';
diff --git a/pkgs/development/python-modules/aiohttp/default.nix b/pkgs/development/python-modules/aiohttp/default.nix
index 3d681d212dfc55..3e42865a5c7f84 100644
--- a/pkgs/development/python-modules/aiohttp/default.nix
+++ b/pkgs/development/python-modules/aiohttp/default.nix
@@ -135,8 +135,6 @@ buildPythonPackage rec {
       # aiohttp in current folder shadows installed version
       rm -r aiohttp
       touch tests/data.unknown_mime_type # has to be modified after 1 Jan 1990
-
-      export HOME=$(mktemp -d)
     ''
     + lib.optionalString stdenv.hostPlatform.isDarwin ''
       # Work around "OSError: AF_UNIX path too long"
diff --git a/pkgs/development/python-modules/amqtt/default.nix b/pkgs/development/python-modules/amqtt/default.nix
index 0221295513b34e..948f869ecc1cbc 100644
--- a/pkgs/development/python-modules/amqtt/default.nix
+++ b/pkgs/development/python-modules/amqtt/default.nix
@@ -75,11 +75,6 @@ buildPythonPackage rec {
     "tests/test_client.py"
   ];
 
-  preCheck = ''
-    # Some tests need amqtt
-    export PATH=$out/bin:$PATH
-  '';
-
   pythonImportsCheck = [ "amqtt" ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/ansi2html/default.nix b/pkgs/development/python-modules/ansi2html/default.nix
index 9ab201720ddf86..8324c4501c440c 100644
--- a/pkgs/development/python-modules/ansi2html/default.nix
+++ b/pkgs/development/python-modules/ansi2html/default.nix
@@ -24,8 +24,6 @@ buildPythonPackage rec {
     wheel
   ];
 
-  preCheck = "export PATH=$PATH:$out/bin";
-
   nativeCheckInputs = [ pytestCheckHook ];
 
   pythonImportsCheck = [ "ansi2html" ];
diff --git a/pkgs/development/python-modules/ansible-compat/default.nix b/pkgs/development/python-modules/ansible-compat/default.nix
index 68eb5fb6a75e5a..a5c703e5fd97b7 100644
--- a/pkgs/development/python-modules/ansible-compat/default.nix
+++ b/pkgs/development/python-modules/ansible-compat/default.nix
@@ -38,7 +38,6 @@ buildPythonPackage rec {
   ];
 
   preCheck = ''
-    export HOME=$(mktemp -d)
     substituteInPlace test/test_runtime.py \
       --replace-fail "printenv" "${coreutils}/bin/printenv"
   '';
diff --git a/pkgs/development/python-modules/ansible-runner/default.nix b/pkgs/development/python-modules/ansible-runner/default.nix
index 11d0f37773e49f..0b7a351aee2f08 100644
--- a/pkgs/development/python-modules/ansible-runner/default.nix
+++ b/pkgs/development/python-modules/ansible-runner/default.nix
@@ -62,8 +62,6 @@ buildPythonPackage rec {
   ];
 
   preCheck = ''
-    export HOME=$(mktemp -d)
-    export PATH="$PATH:$out/bin";
     # avoid coverage flags
     rm pytest.ini
   '';
diff --git a/pkgs/development/python-modules/ansible-vault-rw/default.nix b/pkgs/development/python-modules/ansible-vault-rw/default.nix
index 1a772b3c639f97..0cbc9f503a5655 100644
--- a/pkgs/development/python-modules/ansible-vault-rw/default.nix
+++ b/pkgs/development/python-modules/ansible-vault-rw/default.nix
@@ -28,12 +28,6 @@ buildPythonPackage rec {
 
   propagatedBuildInputs = [ ansible-core ];
 
-  # Otherwise tests will fail to create directory
-  # Permission denied: '/homeless-shelter'
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   # no tests in sdist, no 2.1.0 tag on git
   doCheck = false;
 
diff --git a/pkgs/development/python-modules/appthreat-vulnerability-db/default.nix b/pkgs/development/python-modules/appthreat-vulnerability-db/default.nix
index 3a2916887bafb1..7b3ab30baa8d45 100644
--- a/pkgs/development/python-modules/appthreat-vulnerability-db/default.nix
+++ b/pkgs/development/python-modules/appthreat-vulnerability-db/default.nix
@@ -59,10 +59,6 @@ buildPythonPackage rec {
     pytest-cov-stub
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d);
-  '';
-
   disabledTests = [
     # Tests require network access
     "test_bulk_search"
diff --git a/pkgs/development/python-modules/apptools/default.nix b/pkgs/development/python-modules/apptools/default.nix
index 8540a8f39c4bda..dc508ae6dc2ec1 100644
--- a/pkgs/development/python-modules/apptools/default.nix
+++ b/pkgs/development/python-modules/apptools/default.nix
@@ -48,10 +48,6 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ] ++ lib.flatten (lib.attrValues optional-dependencies);
 
-  preCheck = ''
-    export HOME=$TMP
-  '';
-
   pythonImportsCheck = [ "apptools" ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/arelle/default.nix b/pkgs/development/python-modules/arelle/default.nix
index 6e20880ff84186..abd152a1edb88e 100644
--- a/pkgs/development/python-modules/arelle/default.nix
+++ b/pkgs/development/python-modules/arelle/default.nix
@@ -122,10 +122,6 @@ buildPythonPackage rec {
     boto3
   ] ++ lib.flatten (lib.attrValues optional-dependencies);
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTestPaths =
     [
       "tests/integration_tests"
diff --git a/pkgs/development/python-modules/argilla/default.nix b/pkgs/development/python-modules/argilla/default.nix
index c767e7ca3eed39..fe9502db56a6a8 100644
--- a/pkgs/development/python-modules/argilla/default.nix
+++ b/pkgs/development/python-modules/argilla/default.nix
@@ -169,10 +169,6 @@ buildPythonPackage rec {
   # Still quite a bit of optional dependencies missing
   doCheck = false;
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   nativeCheckInputs = [
     pytestCheckHook
     pytest-mock
diff --git a/pkgs/development/python-modules/aria2p/default.nix b/pkgs/development/python-modules/aria2p/default.nix
index b2ac4e967398d1..9812419d6c04d2 100644
--- a/pkgs/development/python-modules/aria2p/default.nix
+++ b/pkgs/development/python-modules/aria2p/default.nix
@@ -52,10 +52,6 @@ buildPythonPackage rec {
     ];
   };
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   nativeCheckInputs = [
     aria2
     fastapi
diff --git a/pkgs/development/python-modules/arviz/default.nix b/pkgs/development/python-modules/arviz/default.nix
index 563f5d786c498d..0a4ed055aaa355 100644
--- a/pkgs/development/python-modules/arviz/default.nix
+++ b/pkgs/development/python-modules/arviz/default.nix
@@ -82,10 +82,6 @@ buildPythonPackage rec {
     zarr
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d);
-  '';
-
   pytestFlagsArray = [ "arviz/tests/base_tests/" ];
 
   disabledTests = [
diff --git a/pkgs/development/python-modules/asdf-astropy/default.nix b/pkgs/development/python-modules/asdf-astropy/default.nix
index adf443d35961ec..afb7eaa6cede10 100644
--- a/pkgs/development/python-modules/asdf-astropy/default.nix
+++ b/pkgs/development/python-modules/asdf-astropy/default.nix
@@ -54,10 +54,6 @@ buildPythonPackage rec {
 
   pythonImportsCheck = [ "asdf_astropy" ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   meta = with lib; {
     description = "Extension library for ASDF to provide support for Astropy";
     homepage = "https://github.com/astropy/asdf-astropy";
diff --git a/pkgs/development/python-modules/ase/default.nix b/pkgs/development/python-modules/ase/default.nix
index fb8dcd8a599879..bc0f45dbc142fd 100644
--- a/pkgs/development/python-modules/ase/default.nix
+++ b/pkgs/development/python-modules/ase/default.nix
@@ -74,10 +74,6 @@ buildPythonPackage rec {
     "test_fix_scaled" # Did not raise UserWarning
   ] ++ lib.optionals (pythonAtLeast "3.12") [ "test_info_calculators" ];
 
-  preCheck = ''
-    export PATH="$out/bin:$PATH"
-  '';
-
   pythonImportsCheck = [ "ase" ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/aspell-python/default.nix b/pkgs/development/python-modules/aspell-python/default.nix
index 3f66a9a2bf5ddf..ff0a0256d7a254 100644
--- a/pkgs/development/python-modules/aspell-python/default.nix
+++ b/pkgs/development/python-modules/aspell-python/default.nix
@@ -32,7 +32,6 @@ buildPythonPackage rec {
 
   preCheck = ''
     export ASPELL_CONF="dict-dir ${aspellDicts.en}/lib/aspell"
-    export HOME=$(mktemp -d)
   '';
 
   pytestFlagsArray = [ "test/unittests.py" ];
diff --git a/pkgs/development/python-modules/astropy/default.nix b/pkgs/development/python-modules/astropy/default.nix
index 4e26f583b2f9be..ecce215b245563 100644
--- a/pkgs/development/python-modules/astropy/default.nix
+++ b/pkgs/development/python-modules/astropy/default.nix
@@ -130,7 +130,6 @@ buildPythonPackage rec {
   # https://github.com/astropy/astropy/issues/15316#issuecomment-1722190547
   preCheck = ''
     cd "$out"
-    export HOME="$(mktemp -d)"
     export OMP_NUM_THREADS=$(( $NIX_BUILD_CORES / 4 ))
   '';
 
diff --git a/pkgs/development/python-modules/astroquery/default.nix b/pkgs/development/python-modules/astroquery/default.nix
index 7988d75a904471..72a37f8de0f6cd 100644
--- a/pkgs/development/python-modules/astroquery/default.nix
+++ b/pkgs/development/python-modules/astroquery/default.nix
@@ -71,7 +71,6 @@ buildPythonPackage rec {
   # Tests must be run in the build directory. The tests create files
   # in $HOME/.astropy so we need to set HOME to $TMPDIR.
   preCheck = ''
-    export HOME=$TMPDIR
     cd build/lib
   '';
 
diff --git a/pkgs/development/python-modules/aw-client/default.nix b/pkgs/development/python-modules/aw-client/default.nix
index bec43cbf2dbefd..6f8afb47a92939 100644
--- a/pkgs/development/python-modules/aw-client/default.nix
+++ b/pkgs/development/python-modules/aw-client/default.nix
@@ -47,11 +47,6 @@ buildPythonPackage rec {
   # an instance of aw-server running in order to function.
   pytestFlagsArray = [ "tests/test_requestqueue.py" ];
 
-  preCheck = ''
-    # Fake home folder for tests that write to $HOME
-    export HOME="$TMPDIR"
-  '';
-
   pythonImportsCheck = [ "aw_client" ];
 
   passthru.updateScript = gitUpdater { rev-prefix = "v"; };
diff --git a/pkgs/development/python-modules/aw-core/default.nix b/pkgs/development/python-modules/aw-core/default.nix
index 591c862597d528..d0dba3719495c5 100644
--- a/pkgs/development/python-modules/aw-core/default.nix
+++ b/pkgs/development/python-modules/aw-core/default.nix
@@ -55,11 +55,6 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ];
 
-  preCheck = ''
-    # Fake home folder for tests that write to $HOME
-    export HOME="$TMPDIR"
-  '';
-
   pythonImportsCheck = [ "aw_core" ];
 
   passthru.updateScript = gitUpdater { rev-prefix = "v"; };
diff --git a/pkgs/development/python-modules/aws-adfs/default.nix b/pkgs/development/python-modules/aws-adfs/default.nix
index c2c0b859b033cf..c5e3a408d05f09 100644
--- a/pkgs/development/python-modules/aws-adfs/default.nix
+++ b/pkgs/development/python-modules/aws-adfs/default.nix
@@ -57,10 +57,6 @@ buildPythonPackage rec {
     toml
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d);
-  '';
-
   pythonImportsCheck = [ "aws_adfs" ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/bambi/default.nix b/pkgs/development/python-modules/bambi/default.nix
index 20f267b6d8da34..9403f390971fcf 100644
--- a/pkgs/development/python-modules/bambi/default.nix
+++ b/pkgs/development/python-modules/bambi/default.nix
@@ -50,10 +50,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests =
     [
       # Tests require network access
diff --git a/pkgs/development/python-modules/bc-detect-secrets/default.nix b/pkgs/development/python-modules/bc-detect-secrets/default.nix
index ec8170eb2ac137..36f94ad52cc381 100644
--- a/pkgs/development/python-modules/bc-detect-secrets/default.nix
+++ b/pkgs/development/python-modules/bc-detect-secrets/default.nix
@@ -49,10 +49,6 @@ buildPythonPackage rec {
     responses
   ] ++ lib.flatten (builtins.attrValues optional-dependencies);
 
-  preCheck = ''
-    export HOME=$(mktemp -d);
-  '';
-
   disabledTests = [
     # Tests are failing for various reasons (missing git repo, missing test data, etc.)
     "test_baseline_filters_out_known_secrets"
diff --git a/pkgs/development/python-modules/betterproto/default.nix b/pkgs/development/python-modules/betterproto/default.nix
index ab36e1dda56287..c366af19c75f86 100644
--- a/pkgs/development/python-modules/betterproto/default.nix
+++ b/pkgs/development/python-modules/betterproto/default.nix
@@ -62,7 +62,6 @@ buildPythonPackage rec {
   # the protoc-gen-python_betterproto script from the package to be on PATH.
   preCheck = ''
     (($(ulimit -n) < 1024)) && ulimit -n 1024
-    export PATH=$PATH:$out/bin
     patchShebangs src/betterproto/plugin/main.py
     ${python.interpreter} -m tests.generate
   '';
diff --git a/pkgs/development/python-modules/bimmer-connected/default.nix b/pkgs/development/python-modules/bimmer-connected/default.nix
index c9dde5e3ede057..90e767015a4b09 100644
--- a/pkgs/development/python-modules/bimmer-connected/default.nix
+++ b/pkgs/development/python-modules/bimmer-connected/default.nix
@@ -66,7 +66,6 @@ buildPythonPackage rec {
 
   preCheck = ''
     export TZDIR=${tzdata}/${python.sitePackages}/tzdata/zoneinfo
-    export PATH=$out/bin:$PATH
   '';
 
   pythonImportsCheck = [ "bimmer_connected" ];
diff --git a/pkgs/development/python-modules/birch/default.nix b/pkgs/development/python-modules/birch/default.nix
index 772ab25109e4c1..1c1e8e30d499e1 100644
--- a/pkgs/development/python-modules/birch/default.nix
+++ b/pkgs/development/python-modules/birch/default.nix
@@ -54,10 +54,6 @@ buildPythonPackage rec {
     pyyaml
   ];
 
-  preCheck = ''
-    export HOME="$(mktemp -d)"
-  '';
-
   meta = with lib; {
     description = "Simple hierarchical configuration for Python packages";
     homepage = "https://github.com/shaypal5/birch";
diff --git a/pkgs/development/python-modules/black/default.nix b/pkgs/development/python-modules/black/default.nix
index f0cdcf2c2ea422..f4dc9ee92cfac5 100644
--- a/pkgs/development/python-modules/black/default.nix
+++ b/pkgs/development/python-modules/black/default.nix
@@ -80,8 +80,6 @@ buildPythonPackage rec {
 
   preCheck =
     ''
-      export PATH="$PATH:$out/bin"
-
       # The top directory /build matches black's DEFAULT_EXCLUDE regex.
       # Make /build the project root for black tests to avoid excluding files.
       touch ../.git
diff --git a/pkgs/development/python-modules/boiboite-opener-framework/default.nix b/pkgs/development/python-modules/boiboite-opener-framework/default.nix
index 79442baf25b445..b216d368cfa4cf 100644
--- a/pkgs/development/python-modules/boiboite-opener-framework/default.nix
+++ b/pkgs/development/python-modules/boiboite-opener-framework/default.nix
@@ -34,10 +34,6 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   # Race condition, https://github.com/secdev/scapy/pull/4558
   # pythonImportsCheck = [ "bof" ];
 
diff --git a/pkgs/development/python-modules/cartopy/default.nix b/pkgs/development/python-modules/cartopy/default.nix
index 104adf72996898..8704e4fdd24e2c 100644
--- a/pkgs/development/python-modules/cartopy/default.nix
+++ b/pkgs/development/python-modules/cartopy/default.nix
@@ -74,7 +74,6 @@ buildPythonPackage rec {
 
   preCheck = ''
     export FONTCONFIG_FILE=${fontconfig.out}/etc/fonts/fonts.conf
-    export HOME=$TMPDIR
   '';
 
   pytestFlagsArray = [
diff --git a/pkgs/development/python-modules/cassandra-driver/default.nix b/pkgs/development/python-modules/cassandra-driver/default.nix
index f6069e3475e0b5..3379f871f44334 100644
--- a/pkgs/development/python-modules/cassandra-driver/default.nix
+++ b/pkgs/development/python-modules/cassandra-driver/default.nix
@@ -72,7 +72,6 @@ buildPythonPackage rec {
       # increase tolerance for time-based test
       substituteInPlace tests/unit/io/utils.py --replace 'delta=.15' 'delta=.3'
 
-      export HOME=$(mktemp -d)
       # cythonize this before we hide the source dir as it references
       # one of its files
       cythonize -i tests/unit/cython/types_testhelper.pyx
diff --git a/pkgs/development/python-modules/cattrs/default.nix b/pkgs/development/python-modules/cattrs/default.nix
index 8772932278e87e..9815cef1efb3fb 100644
--- a/pkgs/development/python-modules/cattrs/default.nix
+++ b/pkgs/development/python-modules/cattrs/default.nix
@@ -90,10 +90,6 @@ buildPythonPackage rec {
       --replace-fail "from orjson import loads as orjson_loads" ""
   '';
 
-  preCheck = ''
-    export HOME=$(mktemp -d);
-  '';
-
   disabledTestPaths = [
     # Don't run benchmarking tests
     "bench"
diff --git a/pkgs/development/python-modules/censys/default.nix b/pkgs/development/python-modules/censys/default.nix
index 7a3ba89b80419e..797ce1d123d764 100644
--- a/pkgs/development/python-modules/censys/default.nix
+++ b/pkgs/development/python-modules/censys/default.nix
@@ -61,12 +61,6 @@ buildPythonPackage rec {
     "rich"
   ];
 
-  # The tests want to write a configuration file
-  preCheck = ''
-    export HOME=$(mktemp -d)
-    mkdir -p $HOME
-  '';
-
   pythonImportsCheck = [ "censys" ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/cfn-lint/default.nix b/pkgs/development/python-modules/cfn-lint/default.nix
index dad77f086a450b..a7b820e6d57670 100644
--- a/pkgs/development/python-modules/cfn-lint/default.nix
+++ b/pkgs/development/python-modules/cfn-lint/default.nix
@@ -71,10 +71,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ] ++ lib.flatten (builtins.attrValues optional-dependencies);
 
-  preCheck = ''
-    export PATH=$out/bin:$PATH
-  '';
-
   disabledTests = [
     # Requires git directory
     "test_update_docs"
diff --git a/pkgs/development/python-modules/chart-studio/default.nix b/pkgs/development/python-modules/chart-studio/default.nix
index b850ed89301e0f..92b73a80da9713 100644
--- a/pkgs/development/python-modules/chart-studio/default.nix
+++ b/pkgs/development/python-modules/chart-studio/default.nix
@@ -39,10 +39,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   # most tests talk to a network service, so only run ones that don't do that.
   pytestFlagsArray = [
     "chart_studio/tests/test_core"
diff --git a/pkgs/development/python-modules/chromadb/default.nix b/pkgs/development/python-modules/chromadb/default.nix
index 5bb9c0cbffe678..c1da079e91ff92 100644
--- a/pkgs/development/python-modules/chromadb/default.nix
+++ b/pkgs/development/python-modules/chromadb/default.nix
@@ -142,7 +142,6 @@ buildPythonPackage rec {
 
   preCheck = ''
     (($(ulimit -n) < 1024)) && ulimit -n 1024
-    export HOME=$(mktemp -d)
   '';
 
   disabledTests = [
diff --git a/pkgs/development/python-modules/clarifai/default.nix b/pkgs/development/python-modules/clarifai/default.nix
index 124e5cd8d987ed..6ba6e3132c70d5 100644
--- a/pkgs/development/python-modules/clarifai/default.nix
+++ b/pkgs/development/python-modules/clarifai/default.nix
@@ -58,10 +58,6 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests = [
     # Test requires network access and API key
     "test_export_workflow_general"
diff --git a/pkgs/development/python-modules/cleanvision/default.nix b/pkgs/development/python-modules/cleanvision/default.nix
index ff25048ab8869f..d166ece5e2f11d 100644
--- a/pkgs/development/python-modules/cleanvision/default.nix
+++ b/pkgs/development/python-modules/cleanvision/default.nix
@@ -58,10 +58,6 @@ buildPythonPackage rec {
     torchvision
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests = [
     # Requires accessing s3 (online)
     "test_s3_dataset"
diff --git a/pkgs/development/python-modules/click-shell/default.nix b/pkgs/development/python-modules/click-shell/default.nix
index 593b035757b450..865da86556de83 100644
--- a/pkgs/development/python-modules/click-shell/default.nix
+++ b/pkgs/development/python-modules/click-shell/default.nix
@@ -29,8 +29,6 @@ buildPythonPackage rec {
 
   pythonImportsCheck = [ "click_shell" ];
 
-  preCheck = "export HOME=$(mktemp -d)";
-
   meta = with lib; {
     description = "Extension to click that easily turns your click app into a shell utility";
     longDescription = ''
diff --git a/pkgs/development/python-modules/cltk/default.nix b/pkgs/development/python-modules/cltk/default.nix
index 7635ace28648ea..1252b67d2a8d05 100644
--- a/pkgs/development/python-modules/cltk/default.nix
+++ b/pkgs/development/python-modules/cltk/default.nix
@@ -75,10 +75,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   # Most of tests fail as they require local files to be present and also internet access
   doCheck = false;
 
diff --git a/pkgs/development/python-modules/cmdstanpy/default.nix b/pkgs/development/python-modules/cmdstanpy/default.nix
index 6fcf618bafef44..6767c91c3f381d 100644
--- a/pkgs/development/python-modules/cmdstanpy/default.nix
+++ b/pkgs/development/python-modules/cmdstanpy/default.nix
@@ -55,10 +55,6 @@ buildPythonPackage rec {
 
   pythonRelaxDeps = [ "stanio" ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   nativeCheckInputs = [ pytestCheckHook ] ++ optional-dependencies.all;
 
   disabledTestPaths = [
diff --git a/pkgs/development/python-modules/cocotb-bus/default.nix b/pkgs/development/python-modules/cocotb-bus/default.nix
index 6e10559b351095..cee1d1c9feeebb 100644
--- a/pkgs/development/python-modules/cocotb-bus/default.nix
+++ b/pkgs/development/python-modules/cocotb-bus/default.nix
@@ -22,11 +22,6 @@ buildPythonPackage rec {
   # tests require cocotb, disable for now to avoid circular dependency
   doCheck = false;
 
-  # checkPhase = ''
-  #   export PATH=$out/bin:$PATH
-  #   make test
-  # '';
-
   meta = with lib; {
     description = "Pre-packaged testbenching tools and reusable bus interfaces for cocotb";
     homepage = "https://github.com/cocotb/cocotb-bus";
diff --git a/pkgs/development/python-modules/cocotb/default.nix b/pkgs/development/python-modules/cocotb/default.nix
index 028cf7238e6f88..d387d52b9fea0c 100644
--- a/pkgs/development/python-modules/cocotb/default.nix
+++ b/pkgs/development/python-modules/cocotb/default.nix
@@ -62,7 +62,6 @@ buildPythonPackage rec {
   ];
 
   preCheck = ''
-    export PATH=$out/bin:$PATH
     mv cocotb cocotb.hidden
   '';
 
diff --git a/pkgs/development/python-modules/colorcet/default.nix b/pkgs/development/python-modules/colorcet/default.nix
index b335897207fcf0..bc690eac15af90 100644
--- a/pkgs/development/python-modules/colorcet/default.nix
+++ b/pkgs/development/python-modules/colorcet/default.nix
@@ -36,7 +36,6 @@ buildPythonPackage rec {
   ];
 
   preCheck = ''
-    export HOME=$(mktemp -d)
     mkdir -p $HOME/.config/matplotlib
     echo "backend: ps" > $HOME/.config/matplotlib/matplotlibrc
     ln -s $HOME/.config/matplotlib $HOME/.matplotlib
diff --git a/pkgs/development/python-modules/coloredlogs/default.nix b/pkgs/development/python-modules/coloredlogs/default.nix
index c3852dc4ad070b..d7d619ca79b728 100644
--- a/pkgs/development/python-modules/coloredlogs/default.nix
+++ b/pkgs/development/python-modules/coloredlogs/default.nix
@@ -50,11 +50,6 @@ buildPythonPackage rec {
   # https://github.com/xolox/python-capturer/issues/10 is released.
   doCheck = !stdenv.hostPlatform.isDarwin;
 
-  preCheck = ''
-    # Required for the CLI test
-    PATH=$PATH:$out/bin
-  '';
-
   disabledTests = [
     "test_plain_text_output_format"
     "test_auto_install"
diff --git a/pkgs/development/python-modules/compressai/default.nix b/pkgs/development/python-modules/compressai/default.nix
index 15a0f77de90024..2e99a8d80441e1 100644
--- a/pkgs/development/python-modules/compressai/default.nix
+++ b/pkgs/development/python-modules/compressai/default.nix
@@ -70,10 +70,8 @@ buildPythonPackage rec {
   ];
 
   preCheck = ''
-    # We have to delete the source because otherwise it is used intead the installed package.
+    # We have to delete the source because otherwise it is used instead the installed package.
     rm -rf compressai
-
-    export HOME=$(mktemp -d)
   '';
 
   nativeCheckInputs = [
diff --git a/pkgs/development/python-modules/correctionlib/default.nix b/pkgs/development/python-modules/correctionlib/default.nix
index e3d52128ab2dd4..1685446300f90a 100644
--- a/pkgs/development/python-modules/correctionlib/default.nix
+++ b/pkgs/development/python-modules/correctionlib/default.nix
@@ -64,11 +64,6 @@ buildPythonPackage rec {
 
   pythonImportsCheck = [ "correctionlib" ];
 
-  # One test requires running the produced `correctionlib` binary
-  preCheck = ''
-    export PATH=$out/bin:$PATH
-  '';
-
   meta = {
     description = "Provides a well-structured JSON data format for a wide variety of ad-hoc correction factors encountered in a typical HEP analysis";
     mainProgram = "correction";
diff --git a/pkgs/development/python-modules/coveralls/default.nix b/pkgs/development/python-modules/coveralls/default.nix
index c59dd631bf0891..b56fc4bebd7fe6 100644
--- a/pkgs/development/python-modules/coveralls/default.nix
+++ b/pkgs/development/python-modules/coveralls/default.nix
@@ -45,10 +45,6 @@ buildPythonPackage rec {
     git
   ];
 
-  preCheck = ''
-    export PATH=${coverage}/bin:$PATH
-  '';
-
   disabledTests = [
     # requires .git in checkout
     "test_git"
diff --git a/pkgs/development/python-modules/craft-application/default.nix b/pkgs/development/python-modules/craft-application/default.nix
index cc3574d7e3d1ee..09b06a2cabd9df 100644
--- a/pkgs/development/python-modules/craft-application/default.nix
+++ b/pkgs/development/python-modules/craft-application/default.nix
@@ -81,8 +81,6 @@ buildPythonPackage rec {
   ];
 
   preCheck = ''
-    export HOME=$(mktemp -d)
-
     # Tests require access to /etc/os-release, which isn't accessible in
     # the test environment, so create a fake file, and modify the code
     # to look for it.
diff --git a/pkgs/development/python-modules/craft-parts/default.nix b/pkgs/development/python-modules/craft-parts/default.nix
index bececc2a50de46..3761fcade6a53f 100644
--- a/pkgs/development/python-modules/craft-parts/default.nix
+++ b/pkgs/development/python-modules/craft-parts/default.nix
@@ -70,10 +70,6 @@ buildPythonPackage rec {
 
   pytestFlagsArray = [ "tests/unit" ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests = [
     # Relies upon paths not present in Nix (like /bin/bash)
     "test_run_builtin_build"
diff --git a/pkgs/development/python-modules/cwcwidth/default.nix b/pkgs/development/python-modules/cwcwidth/default.nix
index 75b8b091c39b47..d15273177e54ac 100644
--- a/pkgs/development/python-modules/cwcwidth/default.nix
+++ b/pkgs/development/python-modules/cwcwidth/default.nix
@@ -26,7 +26,6 @@ buildPythonPackage rec {
   preCheck = ''
     # Hack needed to make pytest + cython work
     # https://github.com/NixOS/nixpkgs/pull/82410#issuecomment-827186298
-    export HOME=$(mktemp -d)
     cp -r $TMP/$sourceRoot/tests $HOME
     pushd $HOME
 
diff --git a/pkgs/development/python-modules/cysignals/default.nix b/pkgs/development/python-modules/cysignals/default.nix
index 9e90eaf38f19da..ffaf34a34f1048 100644
--- a/pkgs/development/python-modules/cysignals/default.nix
+++ b/pkgs/development/python-modules/cysignals/default.nix
@@ -31,11 +31,6 @@ buildPythonPackage rec {
   doCheck = false;
   checkTarget = "check-install";
 
-  preCheck = ''
-    # Make sure cysignals-CSI is in PATH
-    export PATH="$out/bin:$PATH"
-  '';
-
   propagatedBuildInputs =
     [ cython ]
     ++ lib.optionals pariSupport [
diff --git a/pkgs/development/python-modules/dask-yarn/default.nix b/pkgs/development/python-modules/dask-yarn/default.nix
index a7ba751c3b8692..ab3b47b1d7da7f 100644
--- a/pkgs/development/python-modules/dask-yarn/default.nix
+++ b/pkgs/development/python-modules/dask-yarn/default.nix
@@ -54,10 +54,6 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   pythonImportsCheck = [ "dask_yarn" ];
 
   disabledTests = [
diff --git a/pkgs/development/python-modules/datalad-gooey/default.nix b/pkgs/development/python-modules/datalad-gooey/default.nix
index fcc3fa3763302a..9883c35c81b0ca 100644
--- a/pkgs/development/python-modules/datalad-gooey/default.nix
+++ b/pkgs/development/python-modules/datalad-gooey/default.nix
@@ -41,10 +41,6 @@ buildPythonPackage {
 
   pythonRemoveDeps = [ "applescript" ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   nativeCheckInputs = [
     pytestCheckHook
     pytest-qt
diff --git a/pkgs/development/python-modules/datalad-next/default.nix b/pkgs/development/python-modules/datalad-next/default.nix
index 19b651db3ac616..bffb3c45e46644 100644
--- a/pkgs/development/python-modules/datalad-next/default.nix
+++ b/pkgs/development/python-modules/datalad-next/default.nix
@@ -50,9 +50,6 @@ buildPythonPackage rec {
     more-itertools
   ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
 
   nativeCheckInputs = [
     pytestCheckHook
diff --git a/pkgs/development/python-modules/datalad/default.nix b/pkgs/development/python-modules/datalad/default.nix
index 405a6ea5b3c01f..8a48a4325f39cb 100644
--- a/pkgs/development/python-modules/datalad/default.nix
+++ b/pkgs/development/python-modules/datalad/default.nix
@@ -125,10 +125,6 @@ buildPythonPackage rec {
     wrapProgram $out/bin/datalad --prefix PYTHONPATH : "$PYTHONPATH"
   '';
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   # tests depend on apps in $PATH which only will get installed after the test
   disabledTests = [
     # No such file or directory: 'datalad'
diff --git a/pkgs/development/python-modules/datashader/default.nix b/pkgs/development/python-modules/datashader/default.nix
index 7940e62cb371b6..94e2085ebb0a71 100644
--- a/pkgs/development/python-modules/datashader/default.nix
+++ b/pkgs/development/python-modules/datashader/default.nix
@@ -69,10 +69,6 @@ buildPythonPackage rec {
       --replace "xarray >=0.9.6" "xarray"
   '';
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   pytestFlagsArray = [ "datashader" ];
 
   disabledTests = [
diff --git a/pkgs/development/python-modules/detect-secrets/default.nix b/pkgs/development/python-modules/detect-secrets/default.nix
index 820e204e118a4e..16ba8a897b8a42 100644
--- a/pkgs/development/python-modules/detect-secrets/default.nix
+++ b/pkgs/development/python-modules/detect-secrets/default.nix
@@ -44,10 +44,6 @@ buildPythonPackage rec {
     pkgs.gitMinimal
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d);
-  '';
-
   disabledTests = [
     # Tests are failing for various reasons. Needs to be adjusted with the next update
     "test_basic"
diff --git a/pkgs/development/python-modules/dfdiskcache/default.nix b/pkgs/development/python-modules/dfdiskcache/default.nix
index 60081809002457..50fa4448ef1207 100644
--- a/pkgs/development/python-modules/dfdiskcache/default.nix
+++ b/pkgs/development/python-modules/dfdiskcache/default.nix
@@ -29,11 +29,6 @@ buildPythonPackage rec {
     typing-extensions
   ];
 
-  preCheck = ''
-    # Needed for Permission denied: '/homeless-shelter'
-    export HOME=$(mktemp -d)
-  '';
-
   nativeCheckInputs = [ pytestCheckHook ];
   pythonImportsCheck = [ "dfdiskcache" ];
 
diff --git a/pkgs/development/python-modules/duecredit/default.nix b/pkgs/development/python-modules/duecredit/default.nix
index 5aa4505b919615..a710b511aff27d 100644
--- a/pkgs/development/python-modules/duecredit/default.nix
+++ b/pkgs/development/python-modules/duecredit/default.nix
@@ -42,10 +42,6 @@ buildPythonPackage rec {
   ];
   disabledTests = [ "test_import_doi" ]; # tries to access network
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   pythonImportsCheck = [ "duecredit" ];
 
   meta = {
diff --git a/pkgs/development/python-modules/dufte/default.nix b/pkgs/development/python-modules/dufte/default.nix
index 53ef911b8814e5..4371f490d55e8c 100644
--- a/pkgs/development/python-modules/dufte/default.nix
+++ b/pkgs/development/python-modules/dufte/default.nix
@@ -31,7 +31,6 @@ buildPythonPackage rec {
   ] ++ lib.optionals (pythonOlder "3.8") [ importlib-metadata ];
 
   preCheck = ''
-    export HOME=$(mktemp -d)
     mkdir -p $HOME/.config/matplotlib
     echo "backend: ps" > $HOME/.config/matplotlib/matplotlibrc
     ln -s $HOME/.config/matplotlib $HOME/.matplotlib
diff --git a/pkgs/development/python-modules/dunamai/default.nix b/pkgs/development/python-modules/dunamai/default.nix
index e565ae8b85d361..46520f081aaedc 100644
--- a/pkgs/development/python-modules/dunamai/default.nix
+++ b/pkgs/development/python-modules/dunamai/default.nix
@@ -28,11 +28,7 @@ buildPythonPackage rec {
 
   propagatedBuildInputs = [ packaging ] ++ lib.optionals (pythonOlder "3.8") [ importlib-metadata ];
 
-  # needs to be able to run dunami from PATH
   preCheck = ''
-    export PATH=$PATH:$out/bin
-    export HOME=$(mktemp -d)
-
     git config --global user.email "nobody@example.com"
     git config --global user.name "Nobody"
   '';
diff --git a/pkgs/development/python-modules/einops/default.nix b/pkgs/development/python-modules/einops/default.nix
index 0b1fd24a3ac36a..bd7f1c9ab86d50 100644
--- a/pkgs/development/python-modules/einops/default.nix
+++ b/pkgs/development/python-modules/einops/default.nix
@@ -49,10 +49,6 @@ buildPythonPackage rec {
 
   env.EINOPS_TEST_BACKENDS = "numpy";
 
-  preCheck = ''
-    export HOME=$(mktemp -d);
-  '';
-
   pythonImportsCheck = [ "einops" ];
 
   disabledTests = [
diff --git a/pkgs/development/python-modules/eliot/default.nix b/pkgs/development/python-modules/eliot/default.nix
index eae5b60184cb2e..04f9b1e07ec3e2 100644
--- a/pkgs/development/python-modules/eliot/default.nix
+++ b/pkgs/development/python-modules/eliot/default.nix
@@ -69,11 +69,6 @@ buildPythonPackage rec {
 
   pythonImportsCheck = [ "eliot" ];
 
-  # Tests run eliot-prettyprint in out/bin.
-  preCheck = ''
-    export PATH=$out/bin:$PATH
-  '';
-
   meta = {
     homepage = "https://eliot.readthedocs.io";
     description = "Logging library that tells you why it happened";
diff --git a/pkgs/development/python-modules/evosax/default.nix b/pkgs/development/python-modules/evosax/default.nix
index 08771810c948c8..eab4e8288cd488 100644
--- a/pkgs/development/python-modules/evosax/default.nix
+++ b/pkgs/development/python-modules/evosax/default.nix
@@ -54,10 +54,6 @@ buildPythonPackage rec {
 
   pythonImportsCheck = [ "evosax" ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   nativeCheckInputs = [
     # brax
     # gymnax
diff --git a/pkgs/development/python-modules/faster-whisper/default.nix b/pkgs/development/python-modules/faster-whisper/default.nix
index 42ae02fea649ce..d1348a55f539b8 100644
--- a/pkgs/development/python-modules/faster-whisper/default.nix
+++ b/pkgs/development/python-modules/faster-whisper/default.nix
@@ -54,10 +54,6 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   meta = with lib; {
     changelog = "https://github.com/SYSTRAN/faster-whisper/releases/tag/v${version}";
     description = "Faster Whisper transcription with CTranslate2";
diff --git a/pkgs/development/python-modules/fissix/default.nix b/pkgs/development/python-modules/fissix/default.nix
index d600d8410795fe..94de59bfee302f 100644
--- a/pkgs/development/python-modules/fissix/default.nix
+++ b/pkgs/development/python-modules/fissix/default.nix
@@ -29,10 +29,6 @@ buildPythonPackage {
 
   nativeCheckInputs = [ pytestCheckHook ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   pythonImportsCheck = [ "fissix" ];
 
   meta = {
diff --git a/pkgs/development/python-modules/flickrapi/default.nix b/pkgs/development/python-modules/flickrapi/default.nix
index 9bbd11bd65b6b5..048ee75683cb28 100644
--- a/pkgs/development/python-modules/flickrapi/default.nix
+++ b/pkgs/development/python-modules/flickrapi/default.nix
@@ -46,10 +46,6 @@ buildPythonPackage rec {
     responses
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d);
-  '';
-
   disabledTests = [
     # Tests require network access
     "test_default_format"
diff --git a/pkgs/development/python-modules/fontbakery/default.nix b/pkgs/development/python-modules/fontbakery/default.nix
index 5d7a30fdfa5052..889b871af8aafb 100644
--- a/pkgs/development/python-modules/fontbakery/default.nix
+++ b/pkgs/development/python-modules/fontbakery/default.nix
@@ -118,8 +118,6 @@ buildPythonPackage rec {
   ];
 
   preCheck = ''
-    # Let the tests invoke 'fontbakery' command.
-    export PATH="$out/bin:$PATH"
     # font-v tests assume they are running from a git checkout, although they
     # don't care which one. Create a dummy git repo to satisfy the tests:
     git init -b main
diff --git a/pkgs/development/python-modules/fonttools/default.nix b/pkgs/development/python-modules/fonttools/default.nix
index 555c9cb9bf7b57..08bb13bad31c02 100644
--- a/pkgs/development/python-modules/fonttools/default.nix
+++ b/pkgs/development/python-modules/fonttools/default.nix
@@ -90,11 +90,6 @@ buildPythonPackage rec {
 
   pythonImportsCheck = [ "fontTools" ];
 
-  preCheck = ''
-    # tests want to execute the "fonttools" executable from $PATH
-    export PATH="$out/bin:$PATH"
-  '';
-
   # Timestamp tests have timing issues probably related
   # to our file timestamp normalization
   disabledTests = [
diff --git a/pkgs/development/python-modules/fsspec/default.nix b/pkgs/development/python-modules/fsspec/default.nix
index 8f6e77800b565e..ce3122b1f3e749 100644
--- a/pkgs/development/python-modules/fsspec/default.nix
+++ b/pkgs/development/python-modules/fsspec/default.nix
@@ -92,10 +92,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   __darwinAllowLocalNetworking = true;
 
   disabledTests =
diff --git a/pkgs/development/python-modules/ftfy/default.nix b/pkgs/development/python-modules/ftfy/default.nix
index ec5aca9062a628..67814bf84f40e5 100644
--- a/pkgs/development/python-modules/ftfy/default.nix
+++ b/pkgs/development/python-modules/ftfy/default.nix
@@ -40,10 +40,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export PATH=$out/bin:$PATH
-  '';
-
   meta = with lib; {
     changelog = "https://github.com/rspeer/python-ftfy/blob/${src.rev}/CHANGELOG.md";
     description = "Given Unicode text, make its representation consistent and possibly less broken";
diff --git a/pkgs/development/python-modules/geodatasets/default.nix b/pkgs/development/python-modules/geodatasets/default.nix
index d056d10fe05717..1703d3d777395a 100644
--- a/pkgs/development/python-modules/geodatasets/default.nix
+++ b/pkgs/development/python-modules/geodatasets/default.nix
@@ -34,10 +34,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   pytestFlagsArray = [
     # disable tests which require network access
     "-m 'not request'"
diff --git a/pkgs/development/python-modules/geopandas/default.nix b/pkgs/development/python-modules/geopandas/default.nix
index 4b8f06c50b08cf..2044c42798dfa0 100644
--- a/pkgs/development/python-modules/geopandas/default.nix
+++ b/pkgs/development/python-modules/geopandas/default.nix
@@ -77,10 +77,6 @@ buildPythonPackage rec {
 
   doCheck = !stdenv.hostPlatform.isDarwin;
 
-  preCheck = ''
-    export HOME=$(mktemp -d);
-  '';
-
   disabledTests = [
     # Requires network access
     "test_read_file_url"
diff --git a/pkgs/development/python-modules/glean-parser/default.nix b/pkgs/development/python-modules/glean-parser/default.nix
index 837c2d5d786bfe..a040a0941d9d79 100644
--- a/pkgs/development/python-modules/glean-parser/default.nix
+++ b/pkgs/development/python-modules/glean-parser/default.nix
@@ -45,10 +45,6 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   disabledTests = [
     # Network access
     "test_validate_ping"
diff --git a/pkgs/development/python-modules/globus-sdk/default.nix b/pkgs/development/python-modules/globus-sdk/default.nix
index 7e1cc1c7f737a9..eeefe67d82106c 100644
--- a/pkgs/development/python-modules/globus-sdk/default.nix
+++ b/pkgs/development/python-modules/globus-sdk/default.nix
@@ -29,10 +29,6 @@ buildPythonPackage rec {
 
   build-system = [ setuptools ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   dependencies = [
     cryptography
     requests
diff --git a/pkgs/development/python-modules/glom/default.nix b/pkgs/development/python-modules/glom/default.nix
index 366f75e3bfedcb..980692c648995c 100644
--- a/pkgs/development/python-modules/glom/default.nix
+++ b/pkgs/development/python-modules/glom/default.nix
@@ -39,11 +39,6 @@ buildPythonPackage rec {
     pyyaml
   ];
 
-  preCheck = ''
-    # test_cli.py checks the output of running "glom"
-    export PATH=$out/bin:$PATH
-  '';
-
   disabledTests =
     [
       # Test is outdated (was made for PyYAML 3.x)
diff --git a/pkgs/development/python-modules/glymur/default.nix b/pkgs/development/python-modules/glymur/default.nix
index b9a37779603cf6..8e87a37b72432e 100644
--- a/pkgs/development/python-modules/glymur/default.nix
+++ b/pkgs/development/python-modules/glymur/default.nix
@@ -56,10 +56,6 @@ buildPythonPackage rec {
     scikit-image
   ];
 
-  preCheck = ''
-    export PATH="$out/bin:$PATH"
-  '';
-
   disabledTestPaths = [
     # this test involves glymur's different ways of finding the openjpeg path on
     # fsh systems by reading an .rc file and such, and is obviated by the patch
diff --git a/pkgs/development/python-modules/glyphsets/default.nix b/pkgs/development/python-modules/glyphsets/default.nix
index e95a1a3ecb8387..8ed9a30b2ed98a 100644
--- a/pkgs/development/python-modules/glyphsets/default.nix
+++ b/pkgs/development/python-modules/glyphsets/default.nix
@@ -51,10 +51,6 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ];
 
-  preCheck = ''
-    export PATH="$out/bin:$PATH"
-  '';
-
   disabledTests = [
     # This "test" just tries to connect to PyPI and look for newer releases. Not needed.
     "test_dependencies"
diff --git a/pkgs/development/python-modules/gplaycli/default.nix b/pkgs/development/python-modules/gplaycli/default.nix
index 9303ef9d1450e3..e8ce8219821129 100644
--- a/pkgs/development/python-modules/gplaycli/default.nix
+++ b/pkgs/development/python-modules/gplaycli/default.nix
@@ -47,10 +47,6 @@ buildPythonPackage rec {
 
   pythonImportsCheck = [ "gplaycli" ];
 
-  preCheck = ''
-    export PATH="$PATH:$out/bin";
-  '';
-
   disabledTests = [
     "test_alter_token"
     "test_another_device"
diff --git a/pkgs/development/python-modules/gql/default.nix b/pkgs/development/python-modules/gql/default.nix
index f6067dab3b6da5..e80558e67dd733 100644
--- a/pkgs/development/python-modules/gql/default.nix
+++ b/pkgs/development/python-modules/gql/default.nix
@@ -84,10 +84,6 @@ buildPythonPackage rec {
     botocore = [ botocore ];
   };
 
-  preCheck = ''
-    export PATH=$out/bin:$PATH
-  '';
-
   pytestFlagsArray = [
     "--asyncio-mode=auto"
     "-m 'not online'"
diff --git a/pkgs/development/python-modules/gto/default.nix b/pkgs/development/python-modules/gto/default.nix
index 1ad9a8fbc4c661..005c06a18b5c94 100644
--- a/pkgs/development/python-modules/gto/default.nix
+++ b/pkgs/development/python-modules/gto/default.nix
@@ -64,8 +64,6 @@ buildPythonPackage rec {
   ];
 
   preCheck = ''
-    export HOME=$(mktemp -d)
-
     git config --global user.email "nobody@example.com"
     git config --global user.name "Nobody"
   '';
diff --git a/pkgs/development/python-modules/guidance/default.nix b/pkgs/development/python-modules/guidance/default.nix
index cb153aab3b64d2..4360de5830c316 100644
--- a/pkgs/development/python-modules/guidance/default.nix
+++ b/pkgs/development/python-modules/guidance/default.nix
@@ -89,10 +89,6 @@ buildPythonPackage rec {
     "tests/library/test_gen.py"
   ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   pythonImportsCheck = [ "guidance" ];
 
   __darwinAllowLocalNetworking = true;
diff --git a/pkgs/development/python-modules/habitipy/default.nix b/pkgs/development/python-modules/habitipy/default.nix
index 44548561b349fa..3837a899158e2f 100644
--- a/pkgs/development/python-modules/habitipy/default.nix
+++ b/pkgs/development/python-modules/habitipy/default.nix
@@ -36,10 +36,6 @@ buildPythonPackage rec {
     responses
   ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   disabledTests = [
     # network access
     "test_content_cache"
diff --git a/pkgs/development/python-modules/hatchling/default.nix b/pkgs/development/python-modules/hatchling/default.nix
index 19daf7262e1885..ea5379f8fa48c4 100644
--- a/pkgs/development/python-modules/hatchling/default.nix
+++ b/pkgs/development/python-modules/hatchling/default.nix
@@ -54,10 +54,6 @@ buildPythonPackage rec {
     virtualenv
   ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   checkPhase = ''
     runHook preCheck
     ${python.interpreter} tests/downstream/integrate.py
diff --git a/pkgs/development/python-modules/heudiconv/default.nix b/pkgs/development/python-modules/heudiconv/default.nix
index 6d19a460fde1c7..2ed262631615e9 100644
--- a/pkgs/development/python-modules/heudiconv/default.nix
+++ b/pkgs/development/python-modules/heudiconv/default.nix
@@ -55,10 +55,6 @@ buildPythonPackage rec {
     git
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   pythonImportsCheck = [ "heudiconv" ];
 
   disabledTests = [
diff --git a/pkgs/development/python-modules/hledger-utils/default.nix b/pkgs/development/python-modules/hledger-utils/default.nix
index 0dd811f5a7be54..c12f79525d0a2d 100644
--- a/pkgs/development/python-modules/hledger-utils/default.nix
+++ b/pkgs/development/python-modules/hledger-utils/default.nix
@@ -51,10 +51,6 @@ buildPythonPackage rec {
     perl
   ];
 
-  preCheck = ''
-    export PATH=$out/bin:$PATH
-  '';
-
   meta = with lib; {
     description = "Utilities extending hledger";
     homepage = "https://gitlab.com/nobodyinperson/hledger-utils";
diff --git a/pkgs/development/python-modules/howdoi/default.nix b/pkgs/development/python-modules/howdoi/default.nix
index 4a716b8b037b2a..52d889ca302b3f 100644
--- a/pkgs/development/python-modules/howdoi/default.nix
+++ b/pkgs/development/python-modules/howdoi/default.nix
@@ -59,13 +59,9 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests = [
     "test_colorize"
-    # Tests are flaky, OSError: [Errno 24] Too many open files happpens
+    # Tests are flaky, OSError: [Errno 24] Too many open files happens
     "test_answer_links_using_l_option"
     "test_answers_bing"
     "test_answers"
diff --git a/pkgs/development/python-modules/htseq/default.nix b/pkgs/development/python-modules/htseq/default.nix
index fc965bbae573d1..16c1c4ca87a550 100644
--- a/pkgs/development/python-modules/htseq/default.nix
+++ b/pkgs/development/python-modules/htseq/default.nix
@@ -51,7 +51,6 @@ buildPythonPackage rec {
 
   preCheck = ''
     rm -r src HTSeq
-    export PATH=$out/bin:$PATH
   '';
 
   passthru.updateScript = nix-update-script {
diff --git a/pkgs/development/python-modules/hy/default.nix b/pkgs/development/python-modules/hy/default.nix
index c49c8d6ca5e43f..e93258ededfb6c 100644
--- a/pkgs/development/python-modules/hy/default.nix
+++ b/pkgs/development/python-modules/hy/default.nix
@@ -35,11 +35,6 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ];
 
-  preCheck = ''
-    # For test_bin_hy
-    export PATH="$out/bin:$PATH"
-  '';
-
   pythonImportsCheck = [ "hy" ];
 
   passthru = {
diff --git a/pkgs/development/python-modules/imagededup/default.nix b/pkgs/development/python-modules/imagededup/default.nix
index e6152a3d586aab..858d870f698a75 100644
--- a/pkgs/development/python-modules/imagededup/default.nix
+++ b/pkgs/development/python-modules/imagededup/default.nix
@@ -66,8 +66,6 @@ buildPythonPackage rec {
   ];
 
   preCheck = ''
-    export HOME=$(mktemp -d)
-
     # Checks with CNN are preloaded to avoid downloads in the check phase
     mkdir -p $HOME/.cache/torch/hub/checkpoints/
     ln -s ${MobileNetV3} $HOME/.cache/torch/hub/checkpoints/${MobileNetV3.name}
diff --git a/pkgs/development/python-modules/imbalanced-learn/default.nix b/pkgs/development/python-modules/imbalanced-learn/default.nix
index 09ebc40b7abb62..bce982aaa7347b 100644
--- a/pkgs/development/python-modules/imbalanced-learn/default.nix
+++ b/pkgs/development/python-modules/imbalanced-learn/default.nix
@@ -52,10 +52,6 @@ buildPythonPackage rec {
     pandas
   ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   disabledTestPaths = [
     # require tensorflow and keras, but we don't want to
     # add them to nativeCheckInputs just for this tests
diff --git a/pkgs/development/python-modules/intake/default.nix b/pkgs/development/python-modules/intake/default.nix
index 1422752b323087..d6a665c29b32b8 100644
--- a/pkgs/development/python-modules/intake/default.nix
+++ b/pkgs/development/python-modules/intake/default.nix
@@ -84,11 +84,6 @@ buildPythonPackage rec {
 
   __darwinAllowLocalNetworking = true;
 
-  preCheck = ''
-    export HOME=$(mktemp -d);
-    export PATH="$PATH:$out/bin";
-  '';
-
   disabledTestPaths = [
     # Missing plusins
     "intake/catalog/tests/test_alias.py"
diff --git a/pkgs/development/python-modules/ipdb/default.nix b/pkgs/development/python-modules/ipdb/default.nix
index 9d140f2bebfa24..611d8e728ab22c 100644
--- a/pkgs/development/python-modules/ipdb/default.nix
+++ b/pkgs/development/python-modules/ipdb/default.nix
@@ -40,10 +40,6 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTestPaths =
     [
       # OSError: pytest: reading from stdin while output is captured!  Consider using `-s`.
diff --git a/pkgs/development/python-modules/ipykernel/tests.nix b/pkgs/development/python-modules/ipykernel/tests.nix
index 89ac0be2d3d607..16337b76fe0962 100644
--- a/pkgs/development/python-modules/ipykernel/tests.nix
+++ b/pkgs/development/python-modules/ipykernel/tests.nix
@@ -30,13 +30,9 @@ buildPythonPackage {
     pytest-timeout
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests =
     [
-      # The follwing three tests fail for unclear reasons.
+      # The following three tests fail for unclear reasons.
       # pytest.PytestUnhandledThreadExceptionWarning: Exception in thread Thread-8
       "test_asyncio_interrupt"
 
diff --git a/pkgs/development/python-modules/isort/default.nix b/pkgs/development/python-modules/isort/default.nix
index 32ff65a3914480..d0fd9a16d6363f 100644
--- a/pkgs/development/python-modules/isort/default.nix
+++ b/pkgs/development/python-modules/isort/default.nix
@@ -44,11 +44,6 @@ buildPythonPackage rec {
     )
   '';
 
-  preCheck = ''
-    HOME=$TMPDIR
-    export PATH=$PATH:$out/bin
-  '';
-
   pytestFlagsArray = [
     "--ignore=tests/benchmark/" # requires pytest-benchmark
     "--ignore=tests/integration/" # pulls in 10 other packages
diff --git a/pkgs/development/python-modules/jedi/default.nix b/pkgs/development/python-modules/jedi/default.nix
index 8e31fe41c78056..a5efbe5f5c4580 100644
--- a/pkgs/development/python-modules/jedi/default.nix
+++ b/pkgs/development/python-modules/jedi/default.nix
@@ -40,10 +40,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   disabledTests =
     [
       # sensitive to platform, causes false negatives on darwin
diff --git a/pkgs/development/python-modules/jupysql/default.nix b/pkgs/development/python-modules/jupysql/default.nix
index 56326d52d8378a..0f9763d143a7c6 100644
--- a/pkgs/development/python-modules/jupysql/default.nix
+++ b/pkgs/development/python-modules/jupysql/default.nix
@@ -122,11 +122,6 @@ buildPythonPackage rec {
     "src/tests/test_widget.py"
   ];
 
-  preCheck = ''
-    # tests need to write temp data
-    export HOME=$(mktemp -d)
-  '';
-
   pythonImportsCheck = [ "sql" ];
 
   meta = {
diff --git a/pkgs/development/python-modules/jupyter-book/default.nix b/pkgs/development/python-modules/jupyter-book/default.nix
index c787e16c5cdff0..b6ad76b56c1d49 100644
--- a/pkgs/development/python-modules/jupyter-book/default.nix
+++ b/pkgs/development/python-modules/jupyter-book/default.nix
@@ -89,10 +89,6 @@ buildPythonPackage rec {
     texsoup
   ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   disabledTests = [
     # touch the network
     "test_create_from_cookiecutter"
diff --git a/pkgs/development/python-modules/jupyter-console/default.nix b/pkgs/development/python-modules/jupyter-console/default.nix
index e699d4d2518722..dd98eef0e7353f 100644
--- a/pkgs/development/python-modules/jupyter-console/default.nix
+++ b/pkgs/development/python-modules/jupyter-console/default.nix
@@ -66,10 +66,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   disabledTests = [
     # Flaky: pexpect.exceptions.TIMEOUT: Timeout exceeded
     "test_console_starts"
diff --git a/pkgs/development/python-modules/jupyter-core/default.nix b/pkgs/development/python-modules/jupyter-core/default.nix
index 22453d078491f9..b4bc6c071a63a0 100644
--- a/pkgs/development/python-modules/jupyter-core/default.nix
+++ b/pkgs/development/python-modules/jupyter-core/default.nix
@@ -41,10 +41,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   pytestFlagsArray = [
     # suppress pytest.PytestUnraisableExceptionWarning: Exception ignored in: <socket.socket fd=-1, family=AddressFamily.AF_UNIX, type=SocketKind.SOCK_STREAM, proto=0>
     "-W ignore::pytest.PytestUnraisableExceptionWarning"
diff --git a/pkgs/development/python-modules/jupyter-events/default.nix b/pkgs/development/python-modules/jupyter-events/default.nix
index 6a5431fd1abf98..12478ce30d28ed 100644
--- a/pkgs/development/python-modules/jupyter-events/default.nix
+++ b/pkgs/development/python-modules/jupyter-events/default.nix
@@ -61,10 +61,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ] ++ lib.flatten (builtins.attrValues optional-dependencies);
 
-  preCheck = ''
-    export PATH="$out/bin:$PATH"
-  '';
-
   pythonImportsCheck = [ "jupyter_events" ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/jupyter-packaging/default.nix b/pkgs/development/python-modules/jupyter-packaging/default.nix
index 622e923d1c2757..8ae9763b2369e5 100644
--- a/pkgs/development/python-modules/jupyter-packaging/default.nix
+++ b/pkgs/development/python-modules/jupyter-packaging/default.nix
@@ -49,10 +49,6 @@ buildPythonPackage rec {
 
   pytestFlagsArray = [ "-Wignore::DeprecationWarning" ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests = [
     # disable tests depending on network connection
     "test_develop"
diff --git a/pkgs/development/python-modules/jupyter-server/default.nix b/pkgs/development/python-modules/jupyter-server/default.nix
index 071b3707225ba0..134d006f452bd3 100644
--- a/pkgs/development/python-modules/jupyter-server/default.nix
+++ b/pkgs/development/python-modules/jupyter-server/default.nix
@@ -89,11 +89,6 @@ buildPythonPackage rec {
     "ignore::DeprecationWarning"
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-    export PATH=$out/bin:$PATH
-  '';
-
   disabledTests =
     [
       "test_cull_idle"
diff --git a/pkgs/development/python-modules/jupyter-sphinx/default.nix b/pkgs/development/python-modules/jupyter-sphinx/default.nix
index 89fc4fe88bf538..eb3e3c73b04508 100644
--- a/pkgs/development/python-modules/jupyter-sphinx/default.nix
+++ b/pkgs/development/python-modules/jupyter-sphinx/default.nix
@@ -49,10 +49,6 @@ buildPythonPackage rec {
     "test_builder_priority"
   ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   __darwinAllowLocalNetworking = true;
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/jupyterhub/default.nix b/pkgs/development/python-modules/jupyterhub/default.nix
index 5fb9cc969b59ba..8c1c64581a250b 100644
--- a/pkgs/development/python-modules/jupyterhub/default.nix
+++ b/pkgs/development/python-modules/jupyterhub/default.nix
@@ -127,10 +127,6 @@ buildPythonPackage rec {
     virtualenv
   ];
 
-  preCheck = ''
-    export PATH=$out/bin:$PATH;
-  '';
-
   disabledTests = [
     # Tries to install older versions through pip
     "test_upgrade"
diff --git a/pkgs/development/python-modules/jupyterlab-git/default.nix b/pkgs/development/python-modules/jupyterlab-git/default.nix
index 1ab347130ae1ba..8502739a423258 100644
--- a/pkgs/development/python-modules/jupyterlab-git/default.nix
+++ b/pkgs/development/python-modules/jupyterlab-git/default.nix
@@ -56,10 +56,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   disabledTestPaths = [
     "jupyterlab_git/tests/test_handlers.py"
     # PyPI doesn't ship all required files for the tests
diff --git a/pkgs/development/python-modules/jupyterlab-server/default.nix b/pkgs/development/python-modules/jupyterlab-server/default.nix
index 357b2b29259508..71342e72de8a4a 100644
--- a/pkgs/development/python-modules/jupyterlab-server/default.nix
+++ b/pkgs/development/python-modules/jupyterlab-server/default.nix
@@ -63,10 +63,6 @@ buildPythonPackage rec {
     strict-rfc3339
   ] ++ optional-dependencies.openapi;
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   pytestFlagsArray = [
     "-W"
     "ignore::DeprecationWarning"
diff --git a/pkgs/development/python-modules/jupytext/default.nix b/pkgs/development/python-modules/jupytext/default.nix
index df0fc676633f3c..f75cd338ff6238 100644
--- a/pkgs/development/python-modules/jupytext/default.nix
+++ b/pkgs/development/python-modules/jupytext/default.nix
@@ -50,12 +50,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    # Tests that use a Jupyter notebook require $HOME to be writable
-    export HOME=$(mktemp -d);
-    export PATH=$out/bin:$PATH;
-  '';
-
   disabledTestPaths = [ "tests/external" ];
 
   disabledTests = lib.optionals stdenv.hostPlatform.isDarwin [
diff --git a/pkgs/development/python-modules/keras/default.nix b/pkgs/development/python-modules/keras/default.nix
index d33143d829d52d..44a3c83525ac3e 100644
--- a/pkgs/development/python-modules/keras/default.nix
+++ b/pkgs/development/python-modules/keras/default.nix
@@ -75,10 +75,6 @@ buildPythonPackage rec {
     torch
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests =
     [
       # Tries to install the package in the sandbox
diff --git a/pkgs/development/python-modules/launchpadlib/default.nix b/pkgs/development/python-modules/launchpadlib/default.nix
index da58622e268465..12dafc458a573d 100644
--- a/pkgs/development/python-modules/launchpadlib/default.nix
+++ b/pkgs/development/python-modules/launchpadlib/default.nix
@@ -35,10 +35,6 @@ buildPythonPackage rec {
     testresources
   ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   pythonImportsCheck = [
     "launchpadlib"
     "launchpadlib.apps"
diff --git a/pkgs/development/python-modules/libpysal/default.nix b/pkgs/development/python-modules/libpysal/default.nix
index c81bab3c15127d..484a93574c648f 100644
--- a/pkgs/development/python-modules/libpysal/default.nix
+++ b/pkgs/development/python-modules/libpysal/default.nix
@@ -54,10 +54,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   # requires network access
   disabledTestPaths = [
     "libpysal/graph/tests/test_summary.py"
diff --git a/pkgs/development/python-modules/librosa/default.nix b/pkgs/development/python-modules/librosa/default.nix
index 2c9e2447e33c1b..3bee6ffa788240 100644
--- a/pkgs/development/python-modules/librosa/default.nix
+++ b/pkgs/development/python-modules/librosa/default.nix
@@ -92,10 +92,6 @@ buildPythonPackage rec {
     samplerate
   ] ++ optional-dependencies.matplotlib;
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   disabledTests =
     [
       # requires network access
diff --git a/pkgs/development/python-modules/line-profiler/default.nix b/pkgs/development/python-modules/line-profiler/default.nix
index dce3a93374e0ae..512ff4f63e26c8 100644
--- a/pkgs/development/python-modules/line-profiler/default.nix
+++ b/pkgs/development/python-modules/line-profiler/default.nix
@@ -48,7 +48,6 @@ buildPythonPackage rec {
 
   preCheck = ''
     rm -r line_profiler
-    export PATH=$out/bin:$PATH
   '';
 
   pythonImportsCheck = [ "line_profiler" ];
diff --git a/pkgs/development/python-modules/linien-common/tests.nix b/pkgs/development/python-modules/linien-common/tests.nix
index b95307fce9ac55..24da062ff8ba0e 100644
--- a/pkgs/development/python-modules/linien-common/tests.nix
+++ b/pkgs/development/python-modules/linien-common/tests.nix
@@ -29,10 +29,6 @@ buildPythonPackage {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTestPaths = [
     # require linien-server which is not packaged
     "tests/test_algorithm_selection.py"
diff --git a/pkgs/development/python-modules/macholib/default.nix b/pkgs/development/python-modules/macholib/default.nix
index 6bf2ec3eeeb72d..822343d911011e 100644
--- a/pkgs/development/python-modules/macholib/default.nix
+++ b/pkgs/development/python-modules/macholib/default.nix
@@ -43,10 +43,6 @@ buildPythonPackage rec {
     inherit pyinstaller; # Requires macholib for darwin
   };
 
-  preCheck = ''
-    export PATH="$PATH:$out/bin"
-  '';
-
   meta = with lib; {
     description = "Analyze and edit Mach-O headers, the executable format used by Mac OS X.";
     homepage = "https://github.com/ronaldoussoren/macholib";
diff --git a/pkgs/development/python-modules/maestral/default.nix b/pkgs/development/python-modules/maestral/default.nix
index 52ebece153147c..2cb00b726035ec 100644
--- a/pkgs/development/python-modules/maestral/default.nix
+++ b/pkgs/development/python-modules/maestral/default.nix
@@ -77,10 +77,6 @@ buildPythonPackage rec {
   # ModuleNotFoundError: No module named '_watchdog_fsevents'
   doCheck = !(stdenv.hostPlatform.isDarwin && stdenv.hostPlatform.isx86_64);
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests =
     [
       # We don't want to benchmark
diff --git a/pkgs/development/python-modules/mammoth/default.nix b/pkgs/development/python-modules/mammoth/default.nix
index edb1a5299e50b8..fc26179d1531de 100644
--- a/pkgs/development/python-modules/mammoth/default.nix
+++ b/pkgs/development/python-modules/mammoth/default.nix
@@ -41,10 +41,6 @@ buildPythonPackage rec {
     tempman
   ];
 
-  preCheck = ''
-    export PATH=$out/bin:$PATH
-  '';
-
   passthru.updateScripts = gitUpdater { };
 
   meta = {
diff --git a/pkgs/development/python-modules/manifest-ml/default.nix b/pkgs/development/python-modules/manifest-ml/default.nix
index 80d80d51f93419..a284445335a17b 100644
--- a/pkgs/development/python-modules/manifest-ml/default.nix
+++ b/pkgs/development/python-modules/manifest-ml/default.nix
@@ -86,10 +86,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ] ++ lib.flatten (lib.attrValues optional-dependencies);
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   pytestFlagsArray = [
     # this file tries importing `deepspeed`, which is not yet packaged in nixpkgs
     "--ignore=tests/test_huggingface_api.py"
diff --git a/pkgs/development/python-modules/md2pdf/default.nix b/pkgs/development/python-modules/md2pdf/default.nix
index abcb118aa81887..3bc8288ebd9375 100644
--- a/pkgs/development/python-modules/md2pdf/default.nix
+++ b/pkgs/development/python-modules/md2pdf/default.nix
@@ -42,10 +42,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export PATH="$out/bin:$PATH"
-  '';
-
   meta = {
     changelog = "https://github.com/jmaupetit/md2pdf/blob/${src.rev}/CHANGELOG.md";
     description = "Markdown to PDF conversion tool";
diff --git a/pkgs/development/python-modules/mdtraj/default.nix b/pkgs/development/python-modules/mdtraj/default.nix
index e4a2dc8587e8c8..a87951d65cd792 100644
--- a/pkgs/development/python-modules/mdtraj/default.nix
+++ b/pkgs/development/python-modules/mdtraj/default.nix
@@ -77,7 +77,6 @@ buildPythonPackage rec {
 
   preCheck = ''
     cd tests
-    export PATH=$out/bin:$PATH
   '';
 
   disabledTests = [
diff --git a/pkgs/development/python-modules/meshtastic/default.nix b/pkgs/development/python-modules/meshtastic/default.nix
index 18de6f4c4bb776..6dc5ff049ac130 100644
--- a/pkgs/development/python-modules/meshtastic/default.nix
+++ b/pkgs/development/python-modules/meshtastic/default.nix
@@ -86,10 +86,6 @@ buildPythonPackage rec {
     riden
   ] ++ lib.flatten (builtins.attrValues optional-dependencies);
 
-  preCheck = ''
-    export PATH="$PATH:$out/bin";
-  '';
-
   pythonImportsCheck = [ "meshtastic" ];
 
   disabledTestPaths = [
diff --git a/pkgs/development/python-modules/mike/default.nix b/pkgs/development/python-modules/mike/default.nix
index 934c77440529d5..cc12dec4c6ac2a 100644
--- a/pkgs/development/python-modules/mike/default.nix
+++ b/pkgs/development/python-modules/mike/default.nix
@@ -41,10 +41,6 @@ buildPythonPackage rec {
     unittestCheckHook
   ];
 
-  preCheck = ''
-    export PATH=$out/bin:$PATH
-  '';
-
   # Difficult to setup
   doCheck = false;
 
diff --git a/pkgs/development/python-modules/mitmproxy/default.nix b/pkgs/development/python-modules/mitmproxy/default.nix
index 6248d2e0d47ecb..c802a5274cadc8 100644
--- a/pkgs/development/python-modules/mitmproxy/default.nix
+++ b/pkgs/development/python-modules/mitmproxy/default.nix
@@ -105,10 +105,6 @@ buildPythonPackage rec {
 
   __darwinAllowLocalNetworking = true;
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests = [
     # Tests require a git repository
     "test_get_version"
diff --git a/pkgs/development/python-modules/mmengine/default.nix b/pkgs/development/python-modules/mmengine/default.nix
index 78d3198e4155d6..76d81793b889e8 100644
--- a/pkgs/development/python-modules/mmengine/default.nix
+++ b/pkgs/development/python-modules/mmengine/default.nix
@@ -83,13 +83,10 @@ buildPythonPackage rec {
   ];
 
   preCheck =
-    ''
-      export HOME=$(mktemp -d)
-    ''
     # Otherwise, the backprop hangs forever. More precisely, this exact line:
     # https://github.com/open-mmlab/mmengine/blob/02f80e8bdd38f6713e04a872304861b02157905a/tests/test_runner/test_activation_checkpointing.py#L46
     # Solution suggested in https://github.com/pytorch/pytorch/issues/91547#issuecomment-1370011188
-    + ''
+    ''
       export MKL_NUM_THREADS=1
     '';
 
diff --git a/pkgs/development/python-modules/mne-python/default.nix b/pkgs/development/python-modules/mne-python/default.nix
index 3493806d5fe4e8..78a2b454e4d6aa 100644
--- a/pkgs/development/python-modules/mne-python/default.nix
+++ b/pkgs/development/python-modules/mne-python/default.nix
@@ -68,7 +68,6 @@ buildPythonPackage rec {
   ] ++ lib.flatten (builtins.attrValues optional-dependencies);
 
   preCheck = ''
-    export HOME=$(mktemp -d)
     export MNE_SKIP_TESTING_DATASET_TESTS=true
     export MNE_SKIP_NETWORK_TESTS=1
   '';
diff --git a/pkgs/development/python-modules/naked/default.nix b/pkgs/development/python-modules/naked/default.nix
index adabd6c6f5aa0e..3bc2c3567d7bfa 100644
--- a/pkgs/development/python-modules/naked/default.nix
+++ b/pkgs/development/python-modules/naked/default.nix
@@ -50,8 +50,6 @@ buildPythonPackage rec {
 
   preCheck = ''
     cd tests
-
-    PATH=$PATH:$out/bin
   '';
 
   disabledTestPaths = [ "testfiles" ];
diff --git a/pkgs/development/python-modules/nanoemoji/default.nix b/pkgs/development/python-modules/nanoemoji/default.nix
index 9d2dfffcaf9f1d..37e1f482797709 100644
--- a/pkgs/development/python-modules/nanoemoji/default.nix
+++ b/pkgs/development/python-modules/nanoemoji/default.nix
@@ -86,11 +86,6 @@ buildPythonPackage rec {
     }"
   ];
 
-  preCheck = ''
-    # make sure the built binaries (nanoemoji/maximum_color) can be found by the test
-    export PATH="$out/bin:$PATH"
-  '';
-
   meta = with lib; {
     description = "Wee tool to build color fonts";
     homepage = "https://github.com/googlefonts/nanoemoji";
diff --git a/pkgs/development/python-modules/nbclient/default.nix b/pkgs/development/python-modules/nbclient/default.nix
index 105108d3ab6b65..1488ba056013cb 100644
--- a/pkgs/development/python-modules/nbclient/default.nix
+++ b/pkgs/development/python-modules/nbclient/default.nix
@@ -56,10 +56,6 @@ let
       xmltodict
     ];
 
-    preCheck = ''
-      export HOME=$(mktemp -d)
-    '';
-
     passthru.tests = {
       check = nbclient.overridePythonAttrs (_: {
         doCheck = true;
diff --git a/pkgs/development/python-modules/nbconvert/default.nix b/pkgs/development/python-modules/nbconvert/default.nix
index d13414c125673d..510321c9af594e 100644
--- a/pkgs/development/python-modules/nbconvert/default.nix
+++ b/pkgs/development/python-modules/nbconvert/default.nix
@@ -75,10 +75,6 @@ buildPythonPackage rec {
     traitlets
   ] ++ lib.optionals (pythonOlder "3.10") [ importlib-metadata ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   nativeCheckInputs = [
     flaky
     ipykernel
diff --git a/pkgs/development/python-modules/nbexec/default.nix b/pkgs/development/python-modules/nbexec/default.nix
index 370de0db428c07..0d244b885a160f 100644
--- a/pkgs/development/python-modules/nbexec/default.nix
+++ b/pkgs/development/python-modules/nbexec/default.nix
@@ -43,10 +43,6 @@ buildPythonPackage {
     ipykernel
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   unittestFlagsArray = [
     "-s"
     "test"
diff --git a/pkgs/development/python-modules/nbmake/default.nix b/pkgs/development/python-modules/nbmake/default.nix
index 46ffe613f695c7..d83aa9d86af041 100644
--- a/pkgs/development/python-modules/nbmake/default.nix
+++ b/pkgs/development/python-modules/nbmake/default.nix
@@ -60,10 +60,6 @@ buildPythonPackage rec {
     typing-extensions
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   __darwinAllowLocalNetworking = true;
 
   meta = {
diff --git a/pkgs/development/python-modules/nibabel/default.nix b/pkgs/development/python-modules/nibabel/default.nix
index c0a51cd1dd39e7..d5a566ce9393b8 100644
--- a/pkgs/development/python-modules/nibabel/default.nix
+++ b/pkgs/development/python-modules/nibabel/default.nix
@@ -61,10 +61,6 @@ buildPythonPackage rec {
     pytest7CheckHook
   ] ++ optional-dependencies.all;
 
-  preCheck = ''
-    export PATH=$out/bin:$PATH
-  '';
-
   disabledTestPaths = lib.optionals (pythonAtLeast "3.12") [
     # uses distutils
     "nisext/tests/test_sexts.py"
diff --git a/pkgs/development/python-modules/nicegui/default.nix b/pkgs/development/python-modules/nicegui/default.nix
index 0951e8b5189dd1..0b4c5afd9eb6e0 100644
--- a/pkgs/development/python-modules/nicegui/default.nix
+++ b/pkgs/development/python-modules/nicegui/default.nix
@@ -104,10 +104,6 @@ buildPythonPackage rec {
     webdriver-manager
   ] ++ lib.flatten (builtins.attrValues optional-dependencies);
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   pythonImportsCheck = [ "nicegui" ];
 
   # chromedriver release doesn't seems to be supported, try with next release
diff --git a/pkgs/development/python-modules/niworkflows/default.nix b/pkgs/development/python-modules/niworkflows/default.nix
index 1816cdbd20a38a..784c1b52fe8c8c 100644
--- a/pkgs/development/python-modules/niworkflows/default.nix
+++ b/pkgs/development/python-modules/niworkflows/default.nix
@@ -74,7 +74,6 @@ buildPythonPackage rec {
   env.SETUPTOOLS_SCM_PRETEND_VERSION = version;
 
   nativeCheckInputs = [ pytestCheckHook ];
-  preCheck = ''export HOME=$(mktemp -d)'';
   pytestFlagsArray = [ "niworkflows" ];
   # try to download data:
   disabledTests = [
diff --git a/pkgs/development/python-modules/nox/default.nix b/pkgs/development/python-modules/nox/default.nix
index 9485022155da80..42271c8f51cc7b 100644
--- a/pkgs/development/python-modules/nox/default.nix
+++ b/pkgs/development/python-modules/nox/default.nix
@@ -57,10 +57,6 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ] ++ lib.flatten (builtins.attrValues optional-dependencies);
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   pythonImportsCheck = [ "nox" ];
 
   disabledTests = [
diff --git a/pkgs/development/python-modules/ofxtools/default.nix b/pkgs/development/python-modules/ofxtools/default.nix
index cbf5d5e3c0b2b3..05d09471ddb00b 100644
--- a/pkgs/development/python-modules/ofxtools/default.nix
+++ b/pkgs/development/python-modules/ofxtools/default.nix
@@ -24,9 +24,6 @@ buildPythonPackage rec {
   nativeCheckInputs = [ pytestCheckHook ];
   # override $HOME directory:
   #   error: [Errno 13] Permission denied: '/homeless-shelter'
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
 
   meta = with lib; {
     homepage = "https://github.com/csingley/ofxtools";
diff --git a/pkgs/development/python-modules/onnx/default.nix b/pkgs/development/python-modules/onnx/default.nix
index 0af451607af3dd..6120e8f9752269 100644
--- a/pkgs/development/python-modules/onnx/default.nix
+++ b/pkgs/development/python-modules/onnx/default.nix
@@ -93,8 +93,6 @@ buildPythonPackage rec {
   dontUseCmakeConfigure = true;
 
   preCheck = ''
-    export HOME=$(mktemp -d)
-
     # detecting source dir as a python package confuses pytest
     mv onnx/__init__.py onnx/__init__.py.hidden
   '';
diff --git a/pkgs/development/python-modules/openai-whisper/default.nix b/pkgs/development/python-modules/openai-whisper/default.nix
index 871182550d2adc..408d97fca2b5d6 100644
--- a/pkgs/development/python-modules/openai-whisper/default.nix
+++ b/pkgs/development/python-modules/openai-whisper/default.nix
@@ -55,10 +55,6 @@ buildPythonPackage rec {
     tqdm
   ] ++ lib.optionals (lib.meta.availableOn stdenv.hostPlatform triton) [ triton ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   nativeCheckInputs = [
     pytestCheckHook
     scipy
diff --git a/pkgs/development/python-modules/optuna/default.nix b/pkgs/development/python-modules/optuna/default.nix
index 9df86d3458d843..bb7622c63b6f16 100644
--- a/pkgs/development/python-modules/optuna/default.nix
+++ b/pkgs/development/python-modules/optuna/default.nix
@@ -101,10 +101,6 @@ buildPythonPackage rec {
     ];
   };
 
-  preCheck = ''
-    export PATH=$out/bin:$PATH
-  '';
-
   nativeCheckInputs =
     [
       fakeredis
diff --git a/pkgs/development/python-modules/orange-canvas-core/default.nix b/pkgs/development/python-modules/orange-canvas-core/default.nix
index 3db1f35784bd64..6fe4b82bc1a6a0 100644
--- a/pkgs/development/python-modules/orange-canvas-core/default.nix
+++ b/pkgs/development/python-modules/orange-canvas-core/default.nix
@@ -60,7 +60,6 @@ buildPythonPackage rec {
   pythonImportsCheck = [ "orangecanvas" ];
 
   preCheck = ''
-    export HOME=$(mktemp -d)
     export QT_PLUGIN_PATH="${qt5.qtbase.bin}/${qt5.qtbase.qtPluginPrefix}"
     export QT_QPA_PLATFORM_PLUGIN_PATH="${qt5.qtbase.bin}/lib/qt-${qt5.qtbase.version}/plugins";
     export QT_QPA_PLATFORM=offscreen
diff --git a/pkgs/development/python-modules/orange-widget-base/default.nix b/pkgs/development/python-modules/orange-widget-base/default.nix
index 28c97fdb4238ce..7bb02ff51128bd 100644
--- a/pkgs/development/python-modules/orange-widget-base/default.nix
+++ b/pkgs/development/python-modules/orange-widget-base/default.nix
@@ -37,7 +37,6 @@ buildPythonPackage rec {
   pythonImportsCheck = [ "orangewidget" ];
 
   preCheck = ''
-    export HOME=$(mktemp -d)
     export QT_PLUGIN_PATH="${qt5.qtbase.bin}/${qt5.qtbase.qtPluginPrefix}"
     export QT_QPA_PLATFORM_PLUGIN_PATH="${qt5.qtbase.bin}/lib/qt-${qt5.qtbase.version}/plugins";
     export QT_QPA_PLATFORM=offscreen
diff --git a/pkgs/development/python-modules/osxphotos/default.nix b/pkgs/development/python-modules/osxphotos/default.nix
index f22e7e34d9aa6d..312952a8729889 100644
--- a/pkgs/development/python-modules/osxphotos/default.nix
+++ b/pkgs/development/python-modules/osxphotos/default.nix
@@ -86,10 +86,6 @@ buildPythonPackage rec {
     pytest-mock
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTestPaths = [ "tests/test_comments.py" ];
   disabledTests = [
     "test_iphoto_info"
diff --git a/pkgs/development/python-modules/pandas/default.nix b/pkgs/development/python-modules/pandas/default.nix
index 1e2d51af36273b..b74dd5578c1a3d 100644
--- a/pkgs/development/python-modules/pandas/default.nix
+++ b/pkgs/development/python-modules/pandas/default.nix
@@ -221,7 +221,6 @@ let
     # so change directory where `import .test` is able to be resolved
     preCheck =
       ''
-        export HOME=$TMPDIR
         export LC_ALL="en_US.UTF-8"
         cd $out/${python.sitePackages}/pandas
       ''
diff --git a/pkgs/development/python-modules/papermill/default.nix b/pkgs/development/python-modules/papermill/default.nix
index 6291f013941463..7c3e1053271856 100644
--- a/pkgs/development/python-modules/papermill/default.nix
+++ b/pkgs/development/python-modules/papermill/default.nix
@@ -80,10 +80,6 @@ buildPythonPackage rec {
     ++ optional-dependencies.s3
     ++ optional-dependencies.gcs;
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   pythonImportsCheck = [ "papermill" ];
 
   disabledTests =
diff --git a/pkgs/development/python-modules/papis/default.nix b/pkgs/development/python-modules/papis/default.nix
index c2f4b8f21d6d0f..36bd5f6e2416e5 100644
--- a/pkgs/development/python-modules/papis/default.nix
+++ b/pkgs/development/python-modules/papis/default.nix
@@ -85,10 +85,6 @@ buildPythonPackage rec {
     sphinx-click
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d);
-  '';
-
   pytestFlagsArray = [
     "papis"
     "tests"
diff --git a/pkgs/development/python-modules/pdbfixer/default.nix b/pkgs/development/python-modules/pdbfixer/default.nix
index 0042364a3218fe..a977337390b487 100644
--- a/pkgs/development/python-modules/pdbfixer/default.nix
+++ b/pkgs/development/python-modules/pdbfixer/default.nix
@@ -33,10 +33,6 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ];
 
-  preCheck = ''
-    export PATH=$out/bin:$PATH
-  '';
-
   disabledTests = [
     # require network access
     "test_build_and_simulate"
diff --git a/pkgs/development/python-modules/pdfplumber/default.nix b/pkgs/development/python-modules/pdfplumber/default.nix
index 47e0dd303d462b..8e0c6e8b13b3d5 100644
--- a/pkgs/development/python-modules/pdfplumber/default.nix
+++ b/pkgs/development/python-modules/pdfplumber/default.nix
@@ -41,10 +41,6 @@ buildPythonPackage rec {
     wand
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   nativeCheckInputs = [
     ghostscript
     jupyterlab
diff --git a/pkgs/development/python-modules/persim/default.nix b/pkgs/development/python-modules/persim/default.nix
index 060e3ff8ef72ef..ac649851c047db 100644
--- a/pkgs/development/python-modules/persim/default.nix
+++ b/pkgs/development/python-modules/persim/default.nix
@@ -40,7 +40,6 @@ buildPythonPackage rec {
 
   preCheck = ''
     # specifically needed for darwin
-    export HOME=$(mktemp -d)
     mkdir -p $HOME/.matplotlib
     echo "backend: ps" > $HOME/.matplotlib/matplotlibrc
   '';
diff --git a/pkgs/development/python-modules/pint/default.nix b/pkgs/development/python-modules/pint/default.nix
index e480d1657875e2..ca90db072bab45 100644
--- a/pkgs/development/python-modules/pint/default.nix
+++ b/pkgs/development/python-modules/pint/default.nix
@@ -64,10 +64,6 @@ buildPythonPackage rec {
 
   pytestFlagsArray = [ "--benchmark-disable" ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   meta = {
     changelog = "https://github.com/hgrecco/pint/blob/${version}/CHANGES";
     description = "Physical quantities module";
diff --git a/pkgs/development/python-modules/pipx/default.nix b/pkgs/development/python-modules/pipx/default.nix
index 052ef15fc37329..4b904978f46888 100644
--- a/pkgs/development/python-modules/pipx/default.nix
+++ b/pkgs/development/python-modules/pipx/default.nix
@@ -51,10 +51,6 @@ buildPythonPackage rec {
     git
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   pytestFlagsArray = [
     "--ignore=tests/test_install_all_packages.py"
     # start local pypi server and use in tests
diff --git a/pkgs/development/python-modules/plotnine/default.nix b/pkgs/development/python-modules/plotnine/default.nix
index 6fd63a35390c16..421f0b9aa3dea5 100644
--- a/pkgs/development/python-modules/plotnine/default.nix
+++ b/pkgs/development/python-modules/plotnine/default.nix
@@ -54,10 +54,6 @@ buildPythonPackage rec {
     scikit-misc
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   pythonImportsCheck = [ "plotnine" ];
 
   disabledTests = [
diff --git a/pkgs/development/python-modules/plux/default.nix b/pkgs/development/python-modules/plux/default.nix
index 0ca2084fd8c4e8..d5379c5bd2bf26 100644
--- a/pkgs/development/python-modules/plux/default.nix
+++ b/pkgs/development/python-modules/plux/default.nix
@@ -30,10 +30,6 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   pythonImportsCheck = [ "plugin.core" ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/podman/default.nix b/pkgs/development/python-modules/podman/default.nix
index 24b026b2fe7983..f79a3c7404cb6d 100644
--- a/pkgs/development/python-modules/podman/default.nix
+++ b/pkgs/development/python-modules/podman/default.nix
@@ -44,10 +44,6 @@ buildPythonPackage rec {
     requests-mock
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   pythonImportsCheck = [ "podman" ];
 
   disabledTests = [
diff --git a/pkgs/development/python-modules/pooch/default.nix b/pkgs/development/python-modules/pooch/default.nix
index ed35b18025cebf..d0c296986047c9 100644
--- a/pkgs/development/python-modules/pooch/default.nix
+++ b/pkgs/development/python-modules/pooch/default.nix
@@ -46,10 +46,6 @@ buildPythonPackage rec {
       xxhash = [ xxhash ];
     };
   };
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   nativeCheckInputs = [ pytestCheckHook ];
 
   # tries to touch network
diff --git a/pkgs/development/python-modules/proton-vpn-network-manager/default.nix b/pkgs/development/python-modules/proton-vpn-network-manager/default.nix
index 70a773c0a2655e..02c23b6a6eba1a 100644
--- a/pkgs/development/python-modules/proton-vpn-network-manager/default.nix
+++ b/pkgs/development/python-modules/proton-vpn-network-manager/default.nix
@@ -67,11 +67,6 @@ buildPythonPackage rec {
     pytest-asyncio
   ];
 
-  preCheck = ''
-    # Needed for Permission denied: '/homeless-shelter'
-    export HOME=$(mktemp -d)
-  '';
-
   meta = {
     description = "Provides the necessary functionality for other ProtonVPN components to interact with NetworkManager";
     homepage = "https://github.com/ProtonVPN/python-proton-vpn-network-manager";
diff --git a/pkgs/development/python-modules/proxy-db/default.nix b/pkgs/development/python-modules/proxy-db/default.nix
index 7ccfe3bb890a57..881f781c2ee57f 100644
--- a/pkgs/development/python-modules/proxy-db/default.nix
+++ b/pkgs/development/python-modules/proxy-db/default.nix
@@ -39,10 +39,6 @@ buildPythonPackage rec {
     requests-mock
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   pythonImportsCheck = [ "proxy_db" ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/proxy-py/default.nix b/pkgs/development/python-modules/proxy-py/default.nix
index df174a12558876..dbc6b29ae78b21 100644
--- a/pkgs/development/python-modules/proxy-py/default.nix
+++ b/pkgs/development/python-modules/proxy-py/default.nix
@@ -64,10 +64,6 @@ buildPythonPackage rec {
 
   __darwinAllowLocalNetworking = true;
 
-  preCheck = ''
-    export HOME=$(mktemp -d);
-  '';
-
   disabledTests = [
     # Test requires network access
     "http"
diff --git a/pkgs/development/python-modules/pudb/default.nix b/pkgs/development/python-modules/pudb/default.nix
index 08abae48d113cf..7fd9de0d8bf7b8 100644
--- a/pkgs/development/python-modules/pudb/default.nix
+++ b/pkgs/development/python-modules/pudb/default.nix
@@ -40,10 +40,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   pythonImportsCheck = [ "pudb" ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/pulsectl/default.nix b/pkgs/development/python-modules/pulsectl/default.nix
index 51132de4d5f683..ab64a89796ac15 100644
--- a/pkgs/development/python-modules/pulsectl/default.nix
+++ b/pkgs/development/python-modules/pulsectl/default.nix
@@ -36,10 +36,6 @@ buildPythonPackage rec {
     pulseaudio
   ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   meta = with lib; {
     description = "Python high-level interface and ctypes-based bindings for PulseAudio (libpulse)";
     homepage = "https://github.com/mk-fg/python-pulse-control";
diff --git a/pkgs/development/python-modules/pycookiecheat/default.nix b/pkgs/development/python-modules/pycookiecheat/default.nix
index bc51c78bf551b3..12b3a9b52c1e14 100644
--- a/pkgs/development/python-modules/pycookiecheat/default.nix
+++ b/pkgs/development/python-modules/pycookiecheat/default.nix
@@ -48,10 +48,6 @@ buildPythonPackage rec {
 
   pythonImportsCheck = [ "pycookiecheat" ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests = [
     # Tests want to use playwright executable
     "test_fake_cookie"
diff --git a/pkgs/development/python-modules/pycurl/default.nix b/pkgs/development/python-modules/pycurl/default.nix
index 40aa79a8a7e925..09f9f85ba75d48 100644
--- a/pkgs/development/python-modules/pycurl/default.nix
+++ b/pkgs/development/python-modules/pycurl/default.nix
@@ -60,10 +60,6 @@ buildPythonPackage rec {
     "tests"
   ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   disabledTests =
     [
       # tests that require network access
diff --git a/pkgs/development/python-modules/pydantic/1.nix b/pkgs/development/python-modules/pydantic/1.nix
index cfd0df8c7603a1..a1c4d59de3e375 100644
--- a/pkgs/development/python-modules/pydantic/1.nix
+++ b/pkgs/development/python-modules/pydantic/1.nix
@@ -53,10 +53,6 @@ buildPythonPackage rec {
     "ignore::pytest.PytestReturnNotNoneWarning"
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests = lib.optionals (pythonAtLeast "3.12") [
     # depends on distuils
     "test_cython_function_untouched"
diff --git a/pkgs/development/python-modules/pydantic/default.nix b/pkgs/development/python-modules/pydantic/default.nix
index bb5ba289d5f56b..cf13bd38ba9a01 100644
--- a/pkgs/development/python-modules/pydantic/default.nix
+++ b/pkgs/development/python-modules/pydantic/default.nix
@@ -71,7 +71,6 @@ buildPythonPackage rec {
     ++ lib.optionals (pythonOlder "3.10") [ eval-type-backport ];
 
   preCheck = ''
-    export HOME=$(mktemp -d)
     substituteInPlace pyproject.toml \
       --replace-fail "'--benchmark-columns', 'min,mean,stddev,outliers,rounds,iterations'," "" \
       --replace-fail "'--benchmark-group-by', 'group'," "" \
diff --git a/pkgs/development/python-modules/pygame-ce/default.nix b/pkgs/development/python-modules/pygame-ce/default.nix
index 0c7ef2cebbb9e8..986e949de95d85 100644
--- a/pkgs/development/python-modules/pygame-ce/default.nix
+++ b/pkgs/development/python-modules/pygame-ce/default.nix
@@ -123,7 +123,6 @@ buildPythonPackage rec {
     };
 
   preCheck = ''
-    export HOME=$(mktemp -d)
     # No audio or video device in test environment
     export SDL_VIDEODRIVER=dummy
     export SDL_AUDIODRIVER=disk
diff --git a/pkgs/development/python-modules/pykcs11/tests.nix b/pkgs/development/python-modules/pykcs11/tests.nix
index 00468733ae3093..5531f227392b33 100644
--- a/pkgs/development/python-modules/pykcs11/tests.nix
+++ b/pkgs/development/python-modules/pykcs11/tests.nix
@@ -23,7 +23,6 @@ buildPythonPackage {
   ];
 
   preCheck = ''
-    export HOME=$(mktemp -d)
     export PYKCS11LIB=${softhsm}/lib/softhsm/libsofthsm2.so
     export SOFTHSM2_CONF=$HOME/softhsm2.conf
     echo "directories.tokendir = $HOME/tokens" > $HOME/softhsm2.conf
diff --git a/pkgs/development/python-modules/pymatgen/default.nix b/pkgs/development/python-modules/pymatgen/default.nix
index 6074b06b0bdcfb..d726203d2faf1f 100644
--- a/pkgs/development/python-modules/pymatgen/default.nix
+++ b/pkgs/development/python-modules/pymatgen/default.nix
@@ -83,8 +83,6 @@ buildPythonPackage rec {
   preCheck = ''
     # ensure tests can find these
     export PMG_TEST_FILES_DIR="$(realpath ./tests/files)"
-    # some tests cover the command-line scripts
-    export PATH=$out/bin:$PATH
   '';
 
   pythonImportsCheck = [ "pymatgen" ];
diff --git a/pkgs/development/python-modules/pymupdf/default.nix b/pkgs/development/python-modules/pymupdf/default.nix
index 80bcf8c6117b5f..a2cc795cb3a835 100644
--- a/pkgs/development/python-modules/pymupdf/default.nix
+++ b/pkgs/development/python-modules/pymupdf/default.nix
@@ -121,10 +121,6 @@ buildPythonPackage rec {
     "fitz"
   ];
 
-  preCheck = ''
-    export PATH="$out/bin:$PATH";
-  '';
-
   meta = {
     description = "Python bindings for MuPDF's rendering library";
     homepage = "https://github.com/pymupdf/PyMuPDF";
diff --git a/pkgs/development/python-modules/pyomo/default.nix b/pkgs/development/python-modules/pyomo/default.nix
index 2a9b47803c2cf3..a154bd4dfa8373 100644
--- a/pkgs/development/python-modules/pyomo/default.nix
+++ b/pkgs/development/python-modules/pyomo/default.nix
@@ -34,10 +34,6 @@ buildPythonPackage rec {
 
   pythonImportsCheck = [ "pyomo" ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d);
-  '';
-
   disabledTestPaths = [
     # Don't test the documentation and the examples
     "doc/"
diff --git a/pkgs/development/python-modules/pyopencl/default.nix b/pkgs/development/python-modules/pyopencl/default.nix
index 3af43a63a73c07..db80cac271124e 100644
--- a/pkgs/development/python-modules/pyopencl/default.nix
+++ b/pkgs/development/python-modules/pyopencl/default.nix
@@ -66,8 +66,6 @@ buildPythonPackage rec {
   nativeCheckInputs = [ pytestCheckHook ];
 
   preCheck = ''
-    export HOME=$(mktemp -d)
-
     # https://github.com/NixOS/nixpkgs/issues/255262
     cd $out
   '';
diff --git a/pkgs/development/python-modules/pypass/default.nix b/pkgs/development/python-modules/pypass/default.nix
index 1b9dc08d672008..e93da902d2b7b5 100644
--- a/pkgs/development/python-modules/pypass/default.nix
+++ b/pkgs/development/python-modules/pypass/default.nix
@@ -61,7 +61,6 @@ buildPythonPackage rec {
 
   # Configuration so that the tests work
   preCheck = ''
-    export HOME=$(mktemp -d)
     export GNUPGHOME=pypass/tests/gnupg
     ${git}/bin/git config --global user.email "nix-builder@nixos.org"
     ${git}/bin/git config --global user.name "Nix Builder"
diff --git a/pkgs/development/python-modules/pypiserver/default.nix b/pkgs/development/python-modules/pypiserver/default.nix
index 6202ae3156cf08..2437f1be2c915c 100644
--- a/pkgs/development/python-modules/pypiserver/default.nix
+++ b/pkgs/development/python-modules/pypiserver/default.nix
@@ -63,10 +63,6 @@ buildPythonPackage rec {
     (allow mach-lookup (global-name "com.apple.FSEvents"))
   '';
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   disabledTests = [
     # Fails to install the package
     "test_hash_algos"
diff --git a/pkgs/development/python-modules/pypng/default.nix b/pkgs/development/python-modules/pypng/default.nix
index eb06d04b5dbe73..aecf53b13d765d 100644
--- a/pkgs/development/python-modules/pypng/default.nix
+++ b/pkgs/development/python-modules/pypng/default.nix
@@ -26,11 +26,6 @@ buildPythonPackage rec {
     ./setup-cfg-pngsuite.patch
   ];
 
-  # allow tests to use the binaries produced by this package
-  preCheck = ''
-    export PATH="$out/bin:$PATH"
-  '';
-
   pythonImportsCheck = [
     "png"
     "pngsuite"
diff --git a/pkgs/development/python-modules/pyqtdarktheme/default.nix b/pkgs/development/python-modules/pyqtdarktheme/default.nix
index 2d484122707193..ae982b94f6488f 100644
--- a/pkgs/development/python-modules/pyqtdarktheme/default.nix
+++ b/pkgs/development/python-modules/pyqtdarktheme/default.nix
@@ -48,7 +48,6 @@ buildPythonPackage rec {
   '';
 
   preCheck = ''
-    export HOME=$(mktemp -d)
     export QT_PLUGIN_PATH="${qt5.qtbase.bin}/${qt5.qtbase.qtPluginPrefix}"
     export QT_QPA_PLATFORM_PLUGIN_PATH="${qt5.qtbase.bin}/lib/qt-${qt5.qtbase.version}/plugins";
     export QT_QPA_PLATFORM=offscreen
diff --git a/pkgs/development/python-modules/pyreadstat/default.nix b/pkgs/development/python-modules/pyreadstat/default.nix
index e59530c63a886e..dbe38fdb1ce0f7 100644
--- a/pkgs/development/python-modules/pyreadstat/default.nix
+++ b/pkgs/development/python-modules/pyreadstat/default.nix
@@ -41,10 +41,6 @@ buildPythonPackage rec {
 
   pythonImportsCheck = [ "pyreadstat" ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d);
-  '';
-
   checkPhase = ''
     runHook preCheck
 
diff --git a/pkgs/development/python-modules/pyshark/default.nix b/pkgs/development/python-modules/pyshark/default.nix
index 9dfa464a4139cf..c153fd1323f159 100644
--- a/pkgs/development/python-modules/pyshark/default.nix
+++ b/pkgs/development/python-modules/pyshark/default.nix
@@ -57,10 +57,6 @@ buildPythonPackage rec {
     wireshark-cli
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests =
     [
       # flaky
diff --git a/pkgs/development/python-modules/pytask/default.nix b/pkgs/development/python-modules/pytask/default.nix
index 260b9634b3119c..c31ff0f9fedacb 100644
--- a/pkgs/development/python-modules/pytask/default.nix
+++ b/pkgs/development/python-modules/pytask/default.nix
@@ -63,11 +63,6 @@ buildPythonPackage rec {
     syrupy
   ];
 
-  # The test suite runs the installed command for e2e tests
-  preCheck = ''
-    export PATH="$PATH:$out/bin";
-  '';
-
   disabledTests = [
     # This accesses the network
     "test_download_file"
diff --git a/pkgs/development/python-modules/pytest-ansible/default.nix b/pkgs/development/python-modules/pytest-ansible/default.nix
index 0ddb147a32a07e..9236a70c8c6c1e 100644
--- a/pkgs/development/python-modules/pytest-ansible/default.nix
+++ b/pkgs/development/python-modules/pytest-ansible/default.nix
@@ -48,10 +48,6 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   pytestFlagsArray = [ "tests/" ];
 
   disabledTests =
diff --git a/pkgs/development/python-modules/pytest-bdd/default.nix b/pkgs/development/python-modules/pytest-bdd/default.nix
index 025938b9426474..607fedd1164c69 100644
--- a/pkgs/development/python-modules/pytest-bdd/default.nix
+++ b/pkgs/development/python-modules/pytest-bdd/default.nix
@@ -39,10 +39,6 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ];
 
-  preCheck = ''
-    export PATH=$PATH:$out/bin
-  '';
-
   pythonImportsCheck = [ "pytest_bdd" ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/pytest-benchmark/default.nix b/pkgs/development/python-modules/pytest-benchmark/default.nix
index e66926d4c5cd1d..df77cb1f958c5e 100644
--- a/pkgs/development/python-modules/pytest-benchmark/default.nix
+++ b/pkgs/development/python-modules/pytest-benchmark/default.nix
@@ -57,11 +57,6 @@ buildPythonPackage rec {
     pytest-xdist
   ] ++ lib.flatten (lib.attrValues optional-dependencies);
 
-  preCheck = ''
-    export PATH="$out/bin:$PATH"
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests =
     lib.optionals (pythonOlder "3.12") [
       # AttributeError: 'PluginImportFixer' object has no attribute 'find_spec'
diff --git a/pkgs/development/python-modules/pytest-mypy-plugins/default.nix b/pkgs/development/python-modules/pytest-mypy-plugins/default.nix
index ecc53049ee1ce6..8cd710ffe652d5 100644
--- a/pkgs/development/python-modules/pytest-mypy-plugins/default.nix
+++ b/pkgs/development/python-modules/pytest-mypy-plugins/default.nix
@@ -52,10 +52,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export PATH="$PATH:$out/bin";
-  '';
-
   disabledTestPaths = [ "pytest_mypy_plugins/tests/test_explicit_configs.py" ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/pytest-testinfra/default.nix b/pkgs/development/python-modules/pytest-testinfra/default.nix
index 888233166693c3..c53cd4c24f75c5 100644
--- a/pkgs/development/python-modules/pytest-testinfra/default.nix
+++ b/pkgs/development/python-modules/pytest-testinfra/default.nix
@@ -38,7 +38,6 @@ buildPythonPackage rec {
   # Markers don't get added when docker is not available (leads to warnings):
   # https://github.com/pytest-dev/pytest-testinfra/blob/9.0.0/test/conftest.py#L223
   preCheck = ''
-    export HOME=$(mktemp -d)
     sed -i '54imarkers = \
     \ttestinfra_hosts(host_selector): mark test to run on selected hosts \
     \tdestructive: mark test as destructive \
diff --git a/pkgs/development/python-modules/python-can/default.nix b/pkgs/development/python-modules/python-can/default.nix
index 4272950862f3df..7e1b0d6bd1ecb9 100644
--- a/pkgs/development/python-modules/python-can/default.nix
+++ b/pkgs/development/python-modules/python-can/default.nix
@@ -82,8 +82,7 @@ buildPythonPackage rec {
     ];
 
   preCheck = ''
-    export PATH="$PATH:$out/bin";
-    # skips timing senstive tests
+    # skips timing sensitive tests
     export CI=1
   '';
 
diff --git a/pkgs/development/python-modules/python-creole/default.nix b/pkgs/development/python-modules/python-creole/default.nix
index 53f77d388f5f4b..97aac672c1dc65 100644
--- a/pkgs/development/python-modules/python-creole/default.nix
+++ b/pkgs/development/python-modules/python-creole/default.nix
@@ -57,10 +57,6 @@ buildPythonPackage rec {
     textile
   ];
 
-  preCheck = ''
-    export PATH=$out/bin:$PATH
-  '';
-
   disabledTests = [
     # macro didn't expect argument
     "test_macro_wrong_arguments_quite"
diff --git a/pkgs/development/python-modules/python-escpos/default.nix b/pkgs/development/python-modules/python-escpos/default.nix
index 79db357347147a..6f4a68be544909 100644
--- a/pkgs/development/python-modules/python-escpos/default.nix
+++ b/pkgs/development/python-modules/python-escpos/default.nix
@@ -74,9 +74,6 @@ buildPythonPackage rec {
     # disable checking coverage
     substituteInPlace pyproject.toml \
         --replace-fail "--cov escpos --cov-report=xml" ""
-
-    # allow tests to find the cli executable
-    export PATH="$out/bin:$PATH"
   '';
 
   nativeCheckInputs = [
diff --git a/pkgs/development/python-modules/python-lsp-server/default.nix b/pkgs/development/python-modules/python-lsp-server/default.nix
index 3e64e48a592640..2f89be920a3e82 100644
--- a/pkgs/development/python-modules/python-lsp-server/default.nix
+++ b/pkgs/development/python-modules/python-lsp-server/default.nix
@@ -127,10 +127,6 @@ buildPythonPackage rec {
     "test_jedi_completion_with_fuzzy_enabled"
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d);
-  '';
-
   pythonImportsCheck = [
     "pylsp"
     "pylsp.python_lsp"
diff --git a/pkgs/development/python-modules/qiskit-aer/default.nix b/pkgs/development/python-modules/qiskit-aer/default.nix
index 62c404ff972006..0110459b0d12b2 100644
--- a/pkgs/development/python-modules/qiskit-aer/default.nix
+++ b/pkgs/development/python-modules/qiskit-aer/default.nix
@@ -134,7 +134,6 @@ buildPythonPackage rec {
 
   preCheck = ''
     # Tests include a compiled "circuit" which is auto-built in $HOME
-    export HOME=$(mktemp -d)
     # move tests b/c by default try to find (missing) cython-ized code in /build/source dir
     cp -r $TMP/$sourceRoot/test $HOME
 
diff --git a/pkgs/development/python-modules/qiskit-ignis/default.nix b/pkgs/development/python-modules/qiskit-ignis/default.nix
index a51ad99805b9e2..846112feac60fe 100644
--- a/pkgs/development/python-modules/qiskit-ignis/default.nix
+++ b/pkgs/development/python-modules/qiskit-ignis/default.nix
@@ -50,11 +50,7 @@ buildPythonPackage rec {
 
   # Tests
   pythonImportsCheck = [ "qiskit.ignis" ];
-  dontUseSetuptoolsCheck = true;
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-  nativeCheckInputs = [
+  dontUseSetuptoolsCheck = true;  nativeCheckInputs = [
     pytestCheckHook
     ddt
     pyfakefs
diff --git a/pkgs/development/python-modules/qtile-bonsai/default.nix b/pkgs/development/python-modules/qtile-bonsai/default.nix
index 0edd0eadd7765c..c367c84673d4df 100644
--- a/pkgs/development/python-modules/qtile-bonsai/default.nix
+++ b/pkgs/development/python-modules/qtile-bonsai/default.nix
@@ -45,10 +45,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTestPaths = [
     # Needs a running DBUS
     "tests/integration/test_layout.py"
diff --git a/pkgs/development/python-modules/qtile-extras/default.nix b/pkgs/development/python-modules/qtile-extras/default.nix
index 6157a058dee967..8ad4939feb69ff 100644
--- a/pkgs/development/python-modules/qtile-extras/default.nix
+++ b/pkgs/development/python-modules/qtile-extras/default.nix
@@ -77,7 +77,6 @@ buildPythonPackage rec {
   ];
 
   preCheck = ''
-    export HOME=$(mktemp -d)
     export GDK_PIXBUF_MODULE_FILE=${librsvg}/lib/gdk-pixbuf-2.0/2.10.0/loaders.cache
     sed -i 's#/usr/bin/sleep#sleep#' test/widget/test_snapcast.py
   '';
diff --git a/pkgs/development/python-modules/qutip/default.nix b/pkgs/development/python-modules/qutip/default.nix
index 4907fd55075942..01613a8eaa37b4 100644
--- a/pkgs/development/python-modules/qutip/default.nix
+++ b/pkgs/development/python-modules/qutip/default.nix
@@ -60,7 +60,6 @@ buildPythonPackage rec {
   # This is due to the Cython-compiled modules not being in the correct location
   # of the source tree.
   preCheck = ''
-    export HOME=$(mktemp -d);
     export OMP_NUM_THREADS=$NIX_BUILD_CORES
     mkdir -p test && cd test
   '';
diff --git a/pkgs/development/python-modules/reptor/default.nix b/pkgs/development/python-modules/reptor/default.nix
index db45305baa2a7f..29a2174868224b 100644
--- a/pkgs/development/python-modules/reptor/default.nix
+++ b/pkgs/development/python-modules/reptor/default.nix
@@ -77,11 +77,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ] ++ lib.flatten (builtins.attrValues optional-dependencies);
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-    export PATH="$PATH:$out/bin";
-  '';
-
   pythonImportsCheck = [ "reptor" ];
 
   disabledTestPaths = [
diff --git a/pkgs/development/python-modules/requests-cache/default.nix b/pkgs/development/python-modules/requests-cache/default.nix
index c1e5f1fd6c1b92..4de174d593d4cb 100644
--- a/pkgs/development/python-modules/requests-cache/default.nix
+++ b/pkgs/development/python-modules/requests-cache/default.nix
@@ -84,10 +84,6 @@ buildPythonPackage rec {
     ++ optional-dependencies.json
     ++ optional-dependencies.security;
 
-  preCheck = ''
-    export HOME=$(mktemp -d);
-  '';
-
   pytestFlagsArray = [
     # Integration tests require local DBs
     "tests/unit"
diff --git a/pkgs/development/python-modules/ripser/default.nix b/pkgs/development/python-modules/ripser/default.nix
index d67de41c6d75e7..e9ac1ed3684607 100644
--- a/pkgs/development/python-modules/ripser/default.nix
+++ b/pkgs/development/python-modules/ripser/default.nix
@@ -36,7 +36,6 @@ buildPythonPackage rec {
 
   preCheck = ''
     # specifically needed for darwin
-    export HOME=$(mktemp -d)
     mkdir -p $HOME/.matplotlib
     echo "backend: ps" > $HOME/.matplotlib/matplotlibrc
   '';
diff --git a/pkgs/development/python-modules/rply/default.nix b/pkgs/development/python-modules/rply/default.nix
index 064a7a7a904017..2dd10db12a491e 100644
--- a/pkgs/development/python-modules/rply/default.nix
+++ b/pkgs/development/python-modules/rply/default.nix
@@ -26,10 +26,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   meta = with lib; {
     description = "Python Lex/Yacc that works with RPython";
     homepage = "https://github.com/alex/rply";
diff --git a/pkgs/development/python-modules/rq/default.nix b/pkgs/development/python-modules/rq/default.nix
index 31368014924709..2c4c054b7f7ce4 100644
--- a/pkgs/development/python-modules/rq/default.nix
+++ b/pkgs/development/python-modules/rq/default.nix
@@ -46,7 +46,6 @@ buildPythonPackage rec {
   ];
 
   preCheck = ''
-    PATH=$out/bin:$PATH
     ${redis-server}/bin/redis-server &
   '';
 
diff --git a/pkgs/development/python-modules/rstcheck/default.nix b/pkgs/development/python-modules/rstcheck/default.nix
index 206f9192d92aa9..364ac74f862b3d 100644
--- a/pkgs/development/python-modules/rstcheck/default.nix
+++ b/pkgs/development/python-modules/rstcheck/default.nix
@@ -51,11 +51,6 @@ buildPythonPackage rec {
 
   pythonImportsCheck = [ "rstcheck" ];
 
-  preCheck = ''
-    # The tests need to find and call the rstcheck executable
-    export PATH="$PATH:$out/bin";
-  '';
-
   meta = with lib; {
     description = "Checks syntax of reStructuredText and code blocks nested within it";
     homepage = "https://github.com/myint/rstcheck";
diff --git a/pkgs/development/python-modules/sacrebleu/default.nix b/pkgs/development/python-modules/sacrebleu/default.nix
index 50a3a5d998b7f8..6793660bef54e3 100644
--- a/pkgs/development/python-modules/sacrebleu/default.nix
+++ b/pkgs/development/python-modules/sacrebleu/default.nix
@@ -51,10 +51,6 @@ buildPythonPackage {
     "test/test_dataset.py"
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   pythonImportsCheck = [ "sacrebleu" ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/safety/default.nix b/pkgs/development/python-modules/safety/default.nix
index b3acfb3834bd5d..4c30cae7c83e72 100644
--- a/pkgs/development/python-modules/safety/default.nix
+++ b/pkgs/development/python-modules/safety/default.nix
@@ -94,10 +94,6 @@ buildPythonPackage rec {
   # ImportError: cannot import name 'get_command_for' from partially initialized module 'safety.cli_util' (most likely due to a circular import)
   disabledTestPaths = [ "tests/alerts/test_utils.py" ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   meta = with lib; {
     description = "Checks installed dependencies for known vulnerabilities";
     mainProgram = "safety";
diff --git a/pkgs/development/python-modules/salmon-mail/default.nix b/pkgs/development/python-modules/salmon-mail/default.nix
index 72df3f89e3b9a2..16a8c1d8b54251 100644
--- a/pkgs/development/python-modules/salmon-mail/default.nix
+++ b/pkgs/development/python-modules/salmon-mail/default.nix
@@ -46,12 +46,6 @@ buildPythonPackage rec {
   # https://github.com/NixOS/nixpkgs/pull/82166#discussion_r399909846
   __darwinAllowLocalNetworking = true;
 
-  # The tests use salmon executable installed by salmon itself so we need to add
-  # that to PATH
-  preCheck = ''
-    export PATH=$out/bin:$PATH
-  '';
-
   meta = with lib; {
     homepage = "https://salmon-mail.readthedocs.org/";
     changelog = "https://github.com/moggers87/salmon/blob/${src.rev}/CHANGELOG.rst";
diff --git a/pkgs/development/python-modules/sanic/default.nix b/pkgs/development/python-modules/sanic/default.nix
index 05cdff616166ec..e246d8d0489c7d 100644
--- a/pkgs/development/python-modules/sanic/default.nix
+++ b/pkgs/development/python-modules/sanic/default.nix
@@ -76,7 +76,6 @@ buildPythonPackage rec {
   preCheck =
     ''
       # Some tests depends on sanic on PATH
-      PATH="$out/bin:$PATH"
       PYTHONPATH=$PWD:$PYTHONPATH
 
       # needed for relative paths for some packages
diff --git a/pkgs/development/python-modules/sasmodels/default.nix b/pkgs/development/python-modules/sasmodels/default.nix
index 5443545d5af53e..4666695ce3048e 100644
--- a/pkgs/development/python-modules/sasmodels/default.nix
+++ b/pkgs/development/python-modules/sasmodels/default.nix
@@ -52,10 +52,6 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ] ++ optional-dependencies.full;
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   pythonImportsCheck = [ "sasmodels" ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/scikit-survival/default.nix b/pkgs/development/python-modules/scikit-survival/default.nix
index eb703518964496..1bf8a05f7ccfc5 100644
--- a/pkgs/development/python-modules/scikit-survival/default.nix
+++ b/pkgs/development/python-modules/scikit-survival/default.nix
@@ -60,7 +60,6 @@ buildPythonPackage rec {
   # Hack needed to make pytest + cython work
   # https://github.com/NixOS/nixpkgs/pull/82410#issuecomment-827186298
   preCheck = ''
-    export HOME=$(mktemp -d)
     cp -r $TMP/$sourceRoot/tests $HOME
     pushd $HOME
   '';
diff --git a/pkgs/development/python-modules/scooby/default.nix b/pkgs/development/python-modules/scooby/default.nix
index 90be3a6538722f..367279bafdb462 100644
--- a/pkgs/development/python-modules/scooby/default.nix
+++ b/pkgs/development/python-modules/scooby/default.nix
@@ -37,10 +37,6 @@ buildPythonPackage rec {
     scipy
   ];
 
-  preCheck = ''
-    export PATH="$PATH:$out/bin";
-  '';
-
   pythonImportsCheck = [ "scooby" ];
 
   disabledTests = [
diff --git a/pkgs/development/python-modules/send2trash/default.nix b/pkgs/development/python-modules/send2trash/default.nix
index fe777922e22635..008a22404d5f13 100644
--- a/pkgs/development/python-modules/send2trash/default.nix
+++ b/pkgs/development/python-modules/send2trash/default.nix
@@ -23,10 +23,6 @@ buildPythonPackage rec {
 
   doCheck = !stdenv.hostPlatform.isDarwin;
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   nativeCheckInputs = [ pytestCheckHook ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/setuptools-git-versioning/default.nix b/pkgs/development/python-modules/setuptools-git-versioning/default.nix
index edc6a72c015f79..6219923e7007d4 100644
--- a/pkgs/development/python-modules/setuptools-git-versioning/default.nix
+++ b/pkgs/development/python-modules/setuptools-git-versioning/default.nix
@@ -47,11 +47,6 @@ buildPythonPackage rec {
     toml
   ];
 
-  preCheck = ''
-    # so that its built binary is accessible by tests
-    export PATH="$out/bin:$PATH"
-  '';
-
   # limit tests because the full suite takes several minutes to run
   pytestFlagsArray = [
     "-m"
diff --git a/pkgs/development/python-modules/sh/default.nix b/pkgs/development/python-modules/sh/default.nix
index 06ae4cd49b4d69..6239479747a0e0 100644
--- a/pkgs/development/python-modules/sh/default.nix
+++ b/pkgs/development/python-modules/sh/default.nix
@@ -25,11 +25,6 @@ buildPythonPackage rec {
 
   pytestFlagsArray = [ "tests" ];
 
-  # A test needs the HOME directory to be different from $TMPDIR.
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests =
     [
       # Disable tests that fail on Hydra
diff --git a/pkgs/development/python-modules/shimmy/default.nix b/pkgs/development/python-modules/shimmy/default.nix
index eb19b4e16398bd..2be9d36bd59ed3 100644
--- a/pkgs/development/python-modules/shimmy/default.nix
+++ b/pkgs/development/python-modules/shimmy/default.nix
@@ -76,10 +76,6 @@ buildPythonPackage rec {
     "tests/test_openspiel.py"
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests = [
     # Require network access
     "test_check_env[bsuite/mnist_noise-v0]"
diff --git a/pkgs/development/python-modules/sigstore/default.nix b/pkgs/development/python-modules/sigstore/default.nix
index 99b9674dbb7eb0..da72da0fbde8a7 100644
--- a/pkgs/development/python-modules/sigstore/default.nix
+++ b/pkgs/development/python-modules/sigstore/default.nix
@@ -67,10 +67,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   pythonImportsCheck = [ "sigstore" ];
 
   disabledTests = [
diff --git a/pkgs/development/python-modules/slack-sdk/default.nix b/pkgs/development/python-modules/slack-sdk/default.nix
index 82411d20626e70..b03fc6a3e77d73 100644
--- a/pkgs/development/python-modules/slack-sdk/default.nix
+++ b/pkgs/development/python-modules/slack-sdk/default.nix
@@ -56,10 +56,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests = [
     # Requires internet access (to slack API)
     "test_start_raises_an_error_if_rtm_ws_url_is_not_returned"
diff --git a/pkgs/development/python-modules/snakeviz/default.nix b/pkgs/development/python-modules/snakeviz/default.nix
index c2fd38466ff64b..1c17e00c4a7862 100644
--- a/pkgs/development/python-modules/snakeviz/default.nix
+++ b/pkgs/development/python-modules/snakeviz/default.nix
@@ -38,10 +38,6 @@ buildPythonPackage rec {
 
   pythonImportsCheck = [ "snakeviz" ];
 
-  preCheck = ''
-    export PATH="$PATH:$out/bin";
-  '';
-
   meta = with lib; {
     description = "Browser based viewer for profiling data";
     mainProgram = "snakeviz";
diff --git a/pkgs/development/python-modules/snowflake-connector-python/default.nix b/pkgs/development/python-modules/snowflake-connector-python/default.nix
index f913ee43a2ff81..7691c6c9cafa59 100644
--- a/pkgs/development/python-modules/snowflake-connector-python/default.nix
+++ b/pkgs/development/python-modules/snowflake-connector-python/default.nix
@@ -74,10 +74,6 @@ buildPythonPackage rec {
     secure-local-storage = [ keyring ];
   };
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   nativeCheckInputs = [
     pytest-xdist
     pytestCheckHook
diff --git a/pkgs/development/python-modules/softlayer/default.nix b/pkgs/development/python-modules/softlayer/default.nix
index 49550048e3596a..0750294e410aec 100644
--- a/pkgs/development/python-modules/softlayer/default.nix
+++ b/pkgs/development/python-modules/softlayer/default.nix
@@ -68,12 +68,6 @@ buildPythonPackage rec {
     zeep
   ];
 
-  # Otherwise soap_tests.py will fail to create directory
-  # Permission denied: '/homeless-shelter'
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   pytestFlagsArray = lib.optionals stdenv.hostPlatform.isDarwin [
     # SoftLayer.exceptions.TransportError: TransportError(0): ('Connection aborted.', ConnectionResetError(54, 'Connection reset by peer'))
     "--deselect=tests/CLI/modules/hardware/hardware_basic_tests.py::HardwareCLITests"
diff --git a/pkgs/development/python-modules/sphinx/default.nix b/pkgs/development/python-modules/sphinx/default.nix
index f39899a2c5b6d6..8243374ebb36fc 100644
--- a/pkgs/development/python-modules/sphinx/default.nix
+++ b/pkgs/development/python-modules/sphinx/default.nix
@@ -95,10 +95,6 @@ buildPythonPackage rec {
     typing-extensions
   ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   disabledTests =
     [
       # requires network access
diff --git a/pkgs/development/python-modules/sqlfmt/default.nix b/pkgs/development/python-modules/sqlfmt/default.nix
index 3d191ea49208aa..d3d339c1c00b63 100644
--- a/pkgs/development/python-modules/sqlfmt/default.nix
+++ b/pkgs/development/python-modules/sqlfmt/default.nix
@@ -54,11 +54,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ] ++ lib.flatten (builtins.attrValues optional-dependencies);
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-    export PATH="$PATH:$out/bin";
-  '';
-
   pythonImportsCheck = [ "sqlfmt" ];
 
   meta = {
diff --git a/pkgs/development/python-modules/ssort/default.nix b/pkgs/development/python-modules/ssort/default.nix
index 6a60f6ab1e5397..b7218de3c724d1 100644
--- a/pkgs/development/python-modules/ssort/default.nix
+++ b/pkgs/development/python-modules/ssort/default.nix
@@ -31,10 +31,6 @@ buildPythonPackage rec {
     pyyaml
   ];
 
-  preCheck = ''
-    export PATH=$out/bin:$PATH
-  '';
-
   meta = {
     description = "Automatically sorting python statements within a module";
     homepage = "https://github.com/bwhmather/ssort";
diff --git a/pkgs/development/python-modules/staticjinja/default.nix b/pkgs/development/python-modules/staticjinja/default.nix
index 2967f11b9aa67d..08bc1af1faa33b 100644
--- a/pkgs/development/python-modules/staticjinja/default.nix
+++ b/pkgs/development/python-modules/staticjinja/default.nix
@@ -48,11 +48,6 @@ buildPythonPackage rec {
     typing-extensions
   ];
 
-  # The tests need to find and call the installed staticjinja executable
-  preCheck = ''
-    export PATH="$PATH:$out/bin";
-  '';
-
   passthru.tests = {
     version = testers.testVersion { package = staticjinja; };
     minimal-template = callPackage ./test-minimal-template { };
diff --git a/pkgs/development/python-modules/subarulink/default.nix b/pkgs/development/python-modules/subarulink/default.nix
index 6adb88a40f3287..982b8f94973254 100644
--- a/pkgs/development/python-modules/subarulink/default.nix
+++ b/pkgs/development/python-modules/subarulink/default.nix
@@ -42,10 +42,6 @@ buildPythonPackage rec {
 
   __darwinAllowLocalNetworking = true;
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   pythonImportsCheck = [ "subarulink" ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/sunpy/default.nix b/pkgs/development/python-modules/sunpy/default.nix
index cc7c01702c3dff..a20de8cea54ab8 100644
--- a/pkgs/development/python-modules/sunpy/default.nix
+++ b/pkgs/development/python-modules/sunpy/default.nix
@@ -105,10 +105,6 @@ buildPythonPackage rec {
   # darwin has write permission issues
   doCheck = stdenv.hostPlatform.isLinux;
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests = [
     "rst"
     "test_sunpy_warnings_logging"
diff --git a/pkgs/development/python-modules/tables/default.nix b/pkgs/development/python-modules/tables/default.nix
index 7dc18cefc48142..2e4b5e2e89887b 100644
--- a/pkgs/development/python-modules/tables/default.nix
+++ b/pkgs/development/python-modules/tables/default.nix
@@ -85,7 +85,6 @@ buildPythonPackage rec {
   nativeCheckInputs = [ pytest ];
 
   preCheck = ''
-    export HOME=$(mktemp -d)
     cd ..
   '';
 
diff --git a/pkgs/development/python-modules/timetagger/default.nix b/pkgs/development/python-modules/timetagger/default.nix
index 15a94ffb05a74f..ddf62e1bcd8074 100644
--- a/pkgs/development/python-modules/timetagger/default.nix
+++ b/pkgs/development/python-modules/timetagger/default.nix
@@ -43,10 +43,6 @@ buildPythonPackage rec {
     uvicorn
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   nativeCheckInputs = [
     nodejs
     pytestCheckHook
diff --git a/pkgs/development/python-modules/timezonefinder/default.nix b/pkgs/development/python-modules/timezonefinder/default.nix
index e869dc7ddc855b..3f1eecb2490ec2 100644
--- a/pkgs/development/python-modules/timezonefinder/default.nix
+++ b/pkgs/development/python-modules/timezonefinder/default.nix
@@ -46,11 +46,6 @@ buildPythonPackage rec {
 
   pythonImportsCheck = [ "timezonefinder" ];
 
-  preCheck = ''
-    # Some tests need the CLI on the PATH
-    export PATH=$out/bin:$PATH
-  '';
-
   meta = with lib; {
     changelog = "https://github.com/jannikmi/timezonefinder/blob/${version}/CHANGELOG.rst";
     description = "Module for finding the timezone of any point on earth (coordinates) offline";
diff --git a/pkgs/development/python-modules/tinygrad/default.nix b/pkgs/development/python-modules/tinygrad/default.nix
index d181f339b5b792..68ec48efee1018 100644
--- a/pkgs/development/python-modules/tinygrad/default.nix
+++ b/pkgs/development/python-modules/tinygrad/default.nix
@@ -130,10 +130,6 @@ buildPythonPackage rec {
     transformers
   ] ++ networkx.optional-dependencies.extra;
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests =
     [
       # Fixed in https://github.com/tinygrad/tinygrad/pull/7792
diff --git a/pkgs/development/python-modules/tokenizers/default.nix b/pkgs/development/python-modules/tokenizers/default.nix
index 81d9c74792be8c..1f5c3cef2f46fd 100644
--- a/pkgs/development/python-modules/tokenizers/default.nix
+++ b/pkgs/development/python-modules/tokenizers/default.nix
@@ -125,10 +125,6 @@ buildPythonPackage rec {
     ln -s ${test-data}/* $sourceRoot/tests/data/
   '';
 
-  preCheck = ''
-    export HOME=$(mktemp -d);
-  '';
-
   pythonImportsCheck = [ "tokenizers" ];
 
   disabledTests = [
diff --git a/pkgs/development/python-modules/tololib/default.nix b/pkgs/development/python-modules/tololib/default.nix
index 9344f14dd0e8a3..dfe90b2a21ba4d 100644
--- a/pkgs/development/python-modules/tololib/default.nix
+++ b/pkgs/development/python-modules/tololib/default.nix
@@ -26,10 +26,6 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ];
 
-  preCheck = ''
-    export PATH="$PATH:$out/bin";
-  '';
-
   pythonImportsCheck = [ "tololib" ];
 
   # Network discovery doesn't work in the sandbox for darwin
diff --git a/pkgs/development/python-modules/torch-geometric/default.nix b/pkgs/development/python-modules/torch-geometric/default.nix
index d1342510d7af5a..86ac7da40c5532 100644
--- a/pkgs/development/python-modules/torch-geometric/default.nix
+++ b/pkgs/development/python-modules/torch-geometric/default.nix
@@ -150,10 +150,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests =
     [
       # TODO: try to re-enable when triton will have been updated to 3.0
diff --git a/pkgs/development/python-modules/torchinfo/default.nix b/pkgs/development/python-modules/torchinfo/default.nix
index a10dad4b10c0ae..d4ded07f638878 100644
--- a/pkgs/development/python-modules/torchinfo/default.nix
+++ b/pkgs/development/python-modules/torchinfo/default.nix
@@ -43,10 +43,6 @@ buildPythonPackage rec {
     transformers
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests = [
     # Skip as it downloads pretrained weights (require network access)
     "test_eval_order_doesnt_matter"
diff --git a/pkgs/development/python-modules/towncrier/default.nix b/pkgs/development/python-modules/towncrier/default.nix
index 580d82133f2d43..41621e39cc5d53 100644
--- a/pkgs/development/python-modules/towncrier/default.nix
+++ b/pkgs/development/python-modules/towncrier/default.nix
@@ -38,10 +38,6 @@ buildPythonPackage rec {
     ++ lib.optionals (pythonOlder "3.10") [ importlib-resources ]
     ++ lib.optionals (pythonOlder "3.11") [ tomli ];
 
-  preCheck = ''
-    export PATH=$out/bin:$PATH
-  '';
-
   nativeCheckInputs = [
     git
     mock
diff --git a/pkgs/development/python-modules/trackpy/default.nix b/pkgs/development/python-modules/trackpy/default.nix
index 91945de8dc89a7..c2845fcddd4139 100644
--- a/pkgs/development/python-modules/trackpy/default.nix
+++ b/pkgs/development/python-modules/trackpy/default.nix
@@ -42,7 +42,6 @@ buildPythonPackage rec {
 
   preCheck = lib.optionalString stdenv.hostPlatform.isDarwin ''
     # specifically needed for darwin
-    export HOME=$(mktemp -d)
     mkdir -p $HOME/.matplotlib
     echo "backend: ps" > $HOME/.matplotlib/matplotlibrc
   '';
diff --git a/pkgs/development/python-modules/trx-python/default.nix b/pkgs/development/python-modules/trx-python/default.nix
index 556cf6118ec908..679dc6b81ef05b 100644
--- a/pkgs/development/python-modules/trx-python/default.nix
+++ b/pkgs/development/python-modules/trx-python/default.nix
@@ -43,10 +43,6 @@ buildPythonPackage rec {
     psutil
   ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   pytestFlagsArray = [ "trx/tests" ];
 
   disabledTestPaths = [
diff --git a/pkgs/development/python-modules/trytond/default.nix b/pkgs/development/python-modules/trytond/default.nix
index c51766df6c907b..7ec222798668e2 100644
--- a/pkgs/development/python-modules/trytond/default.nix
+++ b/pkgs/development/python-modules/trytond/default.nix
@@ -67,7 +67,6 @@ buildPythonPackage rec {
   nativeCheckInputs = [ unittestCheckHook ];
 
   preCheck = ''
-    export HOME=$(mktemp -d)
     export TRYTOND_DATABASE_URI="sqlite://"
     export DB_NAME=":memory:";
   '';
diff --git a/pkgs/development/python-modules/twisted/default.nix b/pkgs/development/python-modules/twisted/default.nix
index c54791543489de..0d733ddd1b01df 100644
--- a/pkgs/development/python-modules/twisted/default.nix
+++ b/pkgs/development/python-modules/twisted/default.nix
@@ -204,15 +204,12 @@ buildPythonPackage rec {
       !(stdenv.hostPlatform.isDarwin && stdenv.hostPlatform.isAarch64)
     ) optional-dependencies.tls;
 
-  preCheck = ''
-    export SOURCE_DATE_EPOCH=315532800
-    export PATH=$out/bin:$PATH
-  '';
-
   checkPhase = ''
     runHook preCheck
-    # race conditions when running in paralell
+
+    # race conditions when running in parallel
     ${python.interpreter} -m twisted.trial -j1 twisted
+
     runHook postCheck
   '';
 
diff --git a/pkgs/development/python-modules/typer/default.nix b/pkgs/development/python-modules/typer/default.nix
index dae031fe710e34..572d57eabb0cf0 100644
--- a/pkgs/development/python-modules/typer/default.nix
+++ b/pkgs/development/python-modules/typer/default.nix
@@ -55,10 +55,6 @@ buildPythonPackage rec {
       procps
     ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d);
-  '';
-
   disabledTests =
     [
       "test_scripts"
diff --git a/pkgs/development/python-modules/ubelt/default.nix b/pkgs/development/python-modules/ubelt/default.nix
index 11491426bd0975..ad0f20265ebc75 100644
--- a/pkgs/development/python-modules/ubelt/default.nix
+++ b/pkgs/development/python-modules/ubelt/default.nix
@@ -47,10 +47,6 @@ buildPythonPackage rec {
     xdoctest
   ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   disabledTests = lib.optionals stdenv.hostPlatform.isDarwin [
     # fail due to sandbox environment
     "CacheStamp.expired"
diff --git a/pkgs/development/python-modules/umap-learn/default.nix b/pkgs/development/python-modules/umap-learn/default.nix
index 9d91c6d94ffafb..2762cb2af49dce 100644
--- a/pkgs/development/python-modules/umap-learn/default.nix
+++ b/pkgs/development/python-modules/umap-learn/default.nix
@@ -69,10 +69,6 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   disabledTests = [
     # Plot functionality requires additional packages.
     # These test also fail with 'RuntimeError: cannot cache function' error.
diff --git a/pkgs/development/python-modules/unstructured-inference/default.nix b/pkgs/development/python-modules/unstructured-inference/default.nix
index 28991d89734a49..82df8351569b76 100644
--- a/pkgs/development/python-modules/unstructured-inference/default.nix
+++ b/pkgs/development/python-modules/unstructured-inference/default.nix
@@ -62,10 +62,6 @@ buildPythonPackage rec {
   # This dependency needs to be updated properly
   doCheck = false;
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests = [
     # not sure why this fails
     "test_get_path_oob_move_deeply_nested"
diff --git a/pkgs/development/python-modules/velbus-aio/default.nix b/pkgs/development/python-modules/velbus-aio/default.nix
index f43ff25f655545..1267478ea00c24 100644
--- a/pkgs/development/python-modules/velbus-aio/default.nix
+++ b/pkgs/development/python-modules/velbus-aio/default.nix
@@ -41,10 +41,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   pythonImportsCheck = [ "velbusaio" ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/virtualenv/default.nix b/pkgs/development/python-modules/virtualenv/default.nix
index 660859b9576945..94f8d897686cd7 100644
--- a/pkgs/development/python-modules/virtualenv/default.nix
+++ b/pkgs/development/python-modules/virtualenv/default.nix
@@ -51,10 +51,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ] ++ lib.optionals (!isPyPy) [ time-machine ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTestPaths = [
     # Ignore tests which require network access
     "tests/unit/create/test_creator.py"
diff --git a/pkgs/development/python-modules/wandb/default.nix b/pkgs/development/python-modules/wandb/default.nix
index 321b42e7abfb18..e293a46c3b0b29 100644
--- a/pkgs/development/python-modules/wandb/default.nix
+++ b/pkgs/development/python-modules/wandb/default.nix
@@ -242,10 +242,6 @@ buildPythonPackage rec {
     tqdm
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTestPaths = [
     # Require docker access
     "tests/release_tests/test_launch"
diff --git a/pkgs/development/python-modules/wcmatch/default.nix b/pkgs/development/python-modules/wcmatch/default.nix
index 4faf5b1805ceb6..99d7b77eaf1a69 100644
--- a/pkgs/development/python-modules/wcmatch/default.nix
+++ b/pkgs/development/python-modules/wcmatch/default.nix
@@ -23,10 +23,6 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTests = [ "TestTilde" ];
 
   pythonImportsCheck = [ "wcmatch" ];
diff --git a/pkgs/development/python-modules/weaviate-client/default.nix b/pkgs/development/python-modules/weaviate-client/default.nix
index fccbb289976eef..fb87b8fbee7f23 100644
--- a/pkgs/development/python-modules/weaviate-client/default.nix
+++ b/pkgs/development/python-modules/weaviate-client/default.nix
@@ -71,7 +71,6 @@ buildPythonPackage rec {
   ];
 
   preCheck = ''
-    export HOME=$(mktemp -d)
     sed -i '/raw.githubusercontent.com/,+1d' test/test_util.py
     substituteInPlace pytest.ini \
       --replace-fail "--benchmark-skip" ""
diff --git a/pkgs/development/python-modules/wfuzz/default.nix b/pkgs/development/python-modules/wfuzz/default.nix
index 71577257d22857..868d6fce80c3fb 100644
--- a/pkgs/development/python-modules/wfuzz/default.nix
+++ b/pkgs/development/python-modules/wfuzz/default.nix
@@ -60,10 +60,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   disabledTestPaths = [
     # The tests are requiring a local web server
     "tests/test_acceptance.py"
diff --git a/pkgs/development/python-modules/whispers/default.nix b/pkgs/development/python-modules/whispers/default.nix
index ad550eafe5207e..1f4876b8ba808a 100644
--- a/pkgs/development/python-modules/whispers/default.nix
+++ b/pkgs/development/python-modules/whispers/default.nix
@@ -72,9 +72,6 @@ buildPythonPackage rec {
     # pinning test highly sensitive to semgrep version
     substituteInPlace tests/unit/test_main.py \
       --replace-fail '("--ast", 421),' ""
-
-    # Some tests need the binary available in PATH
-    export PATH=$out/bin:$PATH
   '';
 
   pythonImportsCheck = [ "whispers" ];
diff --git a/pkgs/development/python-modules/wn/default.nix b/pkgs/development/python-modules/wn/default.nix
index 822a5740d2dd78..71f7632e0d8e2a 100644
--- a/pkgs/development/python-modules/wn/default.nix
+++ b/pkgs/development/python-modules/wn/default.nix
@@ -30,10 +30,6 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   pythonImportsCheck = [ "wn" ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/x-wr-timezone/default.nix b/pkgs/development/python-modules/x-wr-timezone/default.nix
index 90a25e98ee742f..a2a092ce10be7f 100644
--- a/pkgs/development/python-modules/x-wr-timezone/default.nix
+++ b/pkgs/development/python-modules/x-wr-timezone/default.nix
@@ -41,10 +41,6 @@ buildPythonPackage rec {
     pytest-click
   ];
 
-  preCheck = ''
-    export PATH=$out/bin:$PATH
-  '';
-
   pythonImportsCheck = [ "x_wr_timezone" ];
 
   meta = {
diff --git a/pkgs/development/python-modules/xdoctest/default.nix b/pkgs/development/python-modules/xdoctest/default.nix
index db4865f48e29e7..affe0224a6203f 100644
--- a/pkgs/development/python-modules/xdoctest/default.nix
+++ b/pkgs/development/python-modules/xdoctest/default.nix
@@ -26,11 +26,6 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-    export PATH=$out/bin:$PATH
-  '';
-
   pythonImportsCheck = [ "xdoctest" ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/yabadaba/default.nix b/pkgs/development/python-modules/yabadaba/default.nix
index 7d5eb445d58de4..268ddc4dafb5cf 100644
--- a/pkgs/development/python-modules/yabadaba/default.nix
+++ b/pkgs/development/python-modules/yabadaba/default.nix
@@ -46,10 +46,6 @@ buildPythonPackage rec {
 
   pythonImportsCheck = [ "yabadaba" ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d);
-  '';
-
   meta = with lib; {
     description = "Abstraction layer allowing for common interactions with databases and records";
     homepage = "https://github.com/usnistgov/yabadaba";
diff --git a/pkgs/development/python-modules/yamlfix/default.nix b/pkgs/development/python-modules/yamlfix/default.nix
index b8747bc3f0fc84..cb4c8d06631183 100644
--- a/pkgs/development/python-modules/yamlfix/default.nix
+++ b/pkgs/development/python-modules/yamlfix/default.nix
@@ -44,10 +44,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-
   pythonImportsCheck = [ "yamlfix" ];
 
   pytestFlagsArray = [
diff --git a/pkgs/development/python-modules/yte/default.nix b/pkgs/development/python-modules/yte/default.nix
index 3afdf2d243c516..dc60b082e6c80a 100644
--- a/pkgs/development/python-modules/yte/default.nix
+++ b/pkgs/development/python-modules/yte/default.nix
@@ -42,11 +42,6 @@ buildPythonPackage rec {
 
   pytestFlagsArray = [ "tests.py" ];
 
-  preCheck = ''
-    # The CLI test need yte on the PATH
-    export PATH=$out/bin:$PATH
-  '';
-
   meta = with lib; {
     description = "YAML template engine with Python expressions";
     homepage = "https://github.com/koesterlab/yte";
diff --git a/pkgs/development/python-modules/zeep/default.nix b/pkgs/development/python-modules/zeep/default.nix
index 139d4ba8ea54fd..f1fe04d7febd27 100644
--- a/pkgs/development/python-modules/zeep/default.nix
+++ b/pkgs/development/python-modules/zeep/default.nix
@@ -82,10 +82,6 @@ buildPythonPackage rec {
     "test_password_digest"
   ];
 
-  preCheck = ''
-    export HOME=$TMPDIR
-  '';
-
   meta = with lib; {
     changelog = "https://github.com/mvantellingen/python-zeep/releases/tag/${version}";
     description = "Python SOAP client";