diff --git a/nixos/doc/manual/release-notes/rl-2505.section.md b/nixos/doc/manual/release-notes/rl-2505.section.md
index e49aaf52c4a39..982693d23f9bb 100644
--- a/nixos/doc/manual/release-notes/rl-2505.section.md
+++ b/nixos/doc/manual/release-notes/rl-2505.section.md
@@ -50,6 +50,8 @@
 
 - `zammad` has had its support for MySQL removed, since it was never working correctly and is now deprecated upstream. Check the [migration guide](https://docs.zammad.org/en/latest/appendix/migrate-to-postgresql.html) for how to convert your database to PostgreSQL.
 
+- `nodePackages.create-react-native-app` has been removed, as it is deprecated. Upstream suggests using a framework for React Native apps instead.
+
 - `nodePackages.insect` has been removed, as it's deprecated by upstream. The suggested replacement is `numbat`.
 
 - `nodePackages.webpack-dev-server` has been removed, as it should be installed in projects that use it instead.
diff --git a/pkgs/development/node-packages/aliases.nix b/pkgs/development/node-packages/aliases.nix
index 429ff75ee82ff..f64a2a5383e74 100644
--- a/pkgs/development/node-packages/aliases.nix
+++ b/pkgs/development/node-packages/aliases.nix
@@ -85,6 +85,7 @@ mapAliases {
   inherit (pkgs) configurable-http-proxy; # added 2023-08-19
   inherit (pkgs) cordova; # added 2023-08-18
   inherit (pkgs) create-react-app; # added 2023-09-25
+  create-react-native-app = throw "create-react-native-app was removed because it was deprecated. Upstream suggests using a framework for React Native."; # added 2024-12-08
   dat = throw "dat was removed because it was broken"; # added 2023-08-21
   inherit (pkgs) degit; # added 2023-08-18
   inherit (pkgs) diagnostic-languageserver; # added 2024-06-25
diff --git a/pkgs/development/node-packages/node-packages.json b/pkgs/development/node-packages/node-packages.json
index 44aeae70e0601..cce143419c905 100644
--- a/pkgs/development/node-packages/node-packages.json
+++ b/pkgs/development/node-packages/node-packages.json
@@ -71,7 +71,6 @@
 , "conventional-changelog-cli"
 , "cpy-cli"
 , "create-cycle-app"
-, "create-react-native-app"
 , "cspell"
 , "csslint"
 , "dhcp"
diff --git a/pkgs/development/node-packages/node-packages.nix b/pkgs/development/node-packages/node-packages.nix
index 82bb712a42c3d..fa95c792dedad 100644
--- a/pkgs/development/node-packages/node-packages.nix
+++ b/pkgs/development/node-packages/node-packages.nix
@@ -60334,24 +60334,6 @@ in
     bypassCache = true;
     reconstructLock = true;
   };
-  create-react-native-app = nodeEnv.buildNodePackage {
-    name = "create-react-native-app";
-    packageName = "create-react-native-app";
-    version = "4.0.0";
-    src = fetchurl {
-      url = "https://registry.npmjs.org/create-react-native-app/-/create-react-native-app-4.0.0.tgz";
-      sha512 = "YRDkUIC0goqudxbBoSScj7rID1yVPKeRXAQGxasC3cLOk6Z1f7zZ1ZUrVLaLaQYjLwmLxCbkxzZpNGr9wnnY/Q==";
-    };
-    buildInputs = globalBuildInputs;
-    meta = {
-      description = "Create React Native apps with no build configuration.";
-      homepage = "https://github.com/expo/create-react-native-app";
-      license = "BSD-3-Clause";
-    };
-    production = true;
-    bypassCache = true;
-    reconstructLock = true;
-  };
   cspell = nodeEnv.buildNodePackage {
     name = "cspell";
     packageName = "cspell";