diff --git a/pkgs/applications/science/math/cplex/default.nix b/pkgs/applications/science/math/cplex/default.nix
index e80444b70b275..9e2fca3ad3ed7 100644
--- a/pkgs/applications/science/math/cplex/default.nix
+++ b/pkgs/applications/science/math/cplex/default.nix
@@ -1,4 +1,4 @@
-{ lib, stdenv, makeWrapper, openjdk, gtk2, xorg, glibcLocales, releasePath ? null }:
+{ lib, stdenv, autoPatchelfHook, makeDesktopItem, copyDesktopItems, makeWrapper, alsa-lib, glib, glib-networking, gsettings-desktop-schemas, gtk3, libsecret, openjdk, sqlite, unixODBC, gtk2, xorg, glibcLocales, releasePath ? null }:
 
 # To use this package, you need to download your own cplex installer from IBM
 # and override the releasePath attribute to point to the location of the file.
@@ -26,51 +26,97 @@ stdenv.mkDerivation rec {
     else
       releasePath;
 
-  nativeBuildInputs = [ makeWrapper ];
-  buildInputs = [ openjdk gtk2 xorg.libXtst glibcLocales ];
+  nativeBuildInputs = [ autoPatchelfHook copyDesktopItems makeWrapper openjdk ];
+  buildInputs = [ alsa-lib gsettings-desktop-schemas gtk2 sqlite unixODBC xorg.libXtst glibcLocales ];
 
   unpackPhase = "cp $src $name";
 
-  patchPhase = ''
+  postPatch = ''
     sed -i -e 's|/usr/bin/tr"|tr"         |' $name
   '';
 
   buildPhase = ''
+    runHook preBuild
+
      export JAVA_TOOL_OPTIONS=-Djdk.util.zip.disableZip64ExtraFieldValidation=true
-     sh $name LAX_VM ${openjdk}/bin/java -i silent -DLICENSE_ACCEPTED=TRUE -DUSER_INSTALL_DIR=$out
-  '';
+    sh $name LAX_VM "$(command -v java)" -i silent -DLICENSE_ACCEPTED=TRUE -DUSER_INSTALL_DIR=$out
 
-  installPhase = ''
-    mkdir -p $out/bin
-    ln -s $out/opl/bin/x86-64_linux/oplrun\
-      $out/opl/bin/x86-64_linux/oplrunjava\
-      $out/opl/oplide/oplide\
-      $out/cplex/bin/x86-64_linux/cplex\
-      $out/cpoptimizer/bin/x86-64_linux/cpoptimizer\
-      $out/bin
+    runHook postBuild
   '';
 
-  fixupPhase =
-  let
-    libraryPath = lib.makeLibraryPath [ stdenv.cc.cc gtk2 xorg.libXtst ];
+  installPhase = let
+    libraryPath = lib.makeLibraryPath [ stdenv.cc.cc glib gtk2 gtk3 libsecret xorg.libXtst ];
   in ''
-    interpreter=${stdenv.cc.libc}/lib/ld-linux-x86-64.so.2
+    runHook preInstall
 
-    for pgm in $out/opl/bin/x86-64_linux/oplrun $out/opl/bin/x86-64_linux/oplrunjava $out/opl/oplide/oplide;
-    do
-      patchelf --set-interpreter "$interpreter" $pgm;
-      wrapProgram $pgm \
-        --prefix LD_LIBRARY_PATH : $out/opl/bin/x86-64_linux:${libraryPath} \
-        --set LOCALE_ARCHIVE ${glibcLocales}/lib/locale/locale-archive;
-    done
+    mkdir -p $out/bin
 
-    for pgm in $out/cplex/bin/x86-64_linux/cplex $out/cpoptimizer/bin/x86-64_linux/cpoptimizer $out/opl/oplide/jre/bin/*;
+    for pgm in \
+      $out/opl/bin/x86-64_linux/oplrun \
+      $out/opl/bin/x86-64_linux/oplrunjava \
+      $out/opl/oplide/oplide \
+      $out/cplex/bin/x86-64_linux/cplex \
+      $out/cpoptimizer/bin/x86-64_linux/cpoptimizer
     do
-      if grep ELF $pgm > /dev/null;
-      then
-        patchelf --set-interpreter "$interpreter" $pgm;
+      makeWrapperArgs=(
+        --set-default LOCALE_ARCHIVE ${glibcLocales}/lib/locale/locale-archive
+      )
+
+      if [[ "$pgm" = "$out/opl/oplide/oplide" ]]; then
+        makeWrapperArgs+=(
+          --prefix LD_LIBRARY_PATH : ${libraryPath}
+          --prefix GIO_EXTRA_MODULES : "${glib-networking}/lib/gio/modules"
+          --prefix XDG_DATA_DIRS : "$GSETTINGS_SCHEMAS_PATH"
+        )
       fi
+
+      makeWrapper "$pgm" "$out/bin/$(basename "$pgm")" "''${makeWrapperArgs[@]}"
     done
+
+    mkdir -p $out/share/pixmaps
+    ln -s $out/opl/oplide/icon.xpm $out/share/pixmaps/oplide.xpm
+
+    mkdir -p $out/share/doc
+    mv $out/doc $out/share/doc/$name
+
+    mkdir -p $out/share/licenses
+    mv $out/license $out/share/licenses/$name
+
+    runHook postInstall
+  '';
+
+  desktopItems = [
+    (makeDesktopItem {
+      name = "oplide";
+      desktopName = "IBM ILOG CPLEX Optimization Studio";
+      genericName = "Optimization Software";
+      icon = "oplide";
+      exec = "oplide";
+      categories = [ "Development" "IDE" "Math" "Science" ];
+    })
+  ];
+
+  fixupPhase = ''
+    runHook preFixup
+
+    rm -r $out/Uninstall
+
+    bins=(
+      $out/bin/*
+      $out/cplex/bin/x86-64_linux/cplex
+      $out/cplex/bin/x86-64_linux/cplexamp
+      $out/cpoptimizer/bin/x86-64_linux/cpoptimizer
+      $out/opl/bin/x86-64_linux/oplrun
+      $out/opl/bin/x86-64_linux/oplrunjava
+      $out/opl/oplide/jre/bin/*
+      $out/opl/oplide/oplide
+    )
+
+    find $out -type d -exec chmod 755 {} \;
+    find $out -type f -exec chmod 644 {} \;
+    chmod +111 "''${bins[@]}"
+
+    runHook postFixup
   '';
 
   passthru = {
@@ -81,6 +127,7 @@ stdenv.mkDerivation rec {
   meta = with lib; {
     description = "Optimization solver for mathematical programming";
     homepage = "https://www.ibm.com/be-en/marketplace/ibm-ilog-cplex";
+    mainProgram = "cplex";
     sourceProvenance = with sourceTypes; [ binaryNativeCode ];
     license = licenses.unfree;
     platforms = [ "x86_64-linux" ];