diff --git a/pkgs/by-name/ti/tiddit/package.nix b/pkgs/by-name/ti/tiddit/package.nix
new file mode 100644
index 00000000000000..2e71cec61309c4
--- /dev/null
+++ b/pkgs/by-name/ti/tiddit/package.nix
@@ -0,0 +1,44 @@
+{
+  lib,
+  fermi2,
+  ropebwt2,
+  fetchFromGitHub,
+  python3Packages,
+  stdenv,
+}:
+python3Packages.buildPythonApplication {
+  name = "tiddit";
+  version = "3.6.1";
+  pyproject = true;
+  src = fetchFromGitHub {
+    owner = "SciLifeLab";
+    repo = "TIDDIT";
+    rev = "TIDDIT-3.6.1";
+    hash = "sha256-OeqVQJDw0fmSDWIGab2qtTJCzZxqLY2XzRqaTRuPIdI=";
+  };
+
+  build-system = with python3Packages; [
+    setuptools
+    wheel
+  ];
+
+  dependencies = with python3Packages; [
+    cython
+    joblib
+    numpy
+    pysam
+  ];
+  propagatedBuildInputs = [
+    fermi2
+    ropebwt2
+  ];
+
+  meta = with lib; {
+    homepage = "https://github.com/SciLifeLab/TIDDIT";
+    description = "Identify chromosomal rearrangements using Mate Pair or Paired End sequencing data";
+    mainProgram = "tiddit";
+    license = licenses.gpl3Only;
+    maintainers = with maintainers; [ apraga ];
+    platforms = platforms.unix;
+  };
+}