diff --git a/lib/systems/default.nix b/lib/systems/default.nix
index 00f7f3523aa482..a6bbdf69b30c97 100644
--- a/lib/systems/default.nix
+++ b/lib/systems/default.nix
@@ -91,7 +91,7 @@ let
         && final.parsed.kernel == platform.parsed.kernel;
       isCompatible = _: throw "2022-05-23: isCompatible has been removed in favor of canExecute, refer to the 22.11 changelog for details";
       # Derived meta-data
-      useLLVM = final.isFreeBSD || final.isOpenBSD;
+      useLLVM = final.isFreeBSD || final.isOpenBSD || final.isLLVMLibc;
 
       libc =
         /**/ if final.isDarwin                then "libSystem"
@@ -102,6 +102,7 @@ let
         else if final.isMusl                  then "musl"
         else if final.isUClibc                then "uclibc"
         else if final.isAndroid               then "bionic"
+        else if final.isLLVMLibc              then "llvm"
         else if final.isLinux  /* default */  then "glibc"
         else if final.isFreeBSD               then "fblibc"
         else if final.isOpenBSD               then "oblibc"
diff --git a/lib/systems/inspect.nix b/lib/systems/inspect.nix
index ebc7ab36687634..de4df13cd81166 100644
--- a/lib/systems/inspect.nix
+++ b/lib/systems/inspect.nix
@@ -113,6 +113,7 @@ rec {
     isGnu          = with abis; map (a: { abi = a; }) [ gnuabi64 gnuabin32 gnu gnueabi gnueabihf gnuabielfv1 gnuabielfv2 ];
     isMusl         = with abis; map (a: { abi = a; }) [ musl musleabi musleabihf muslabin32 muslabi64 ];
     isUClibc       = with abis; map (a: { abi = a; }) [ uclibc uclibceabi uclibceabihf ];
+    isLLVMLibc     = [ { abi = abis.llvm; } ];
 
     isEfi = [
       { cpu = { family = "arm"; version = "6"; }; }
diff --git a/lib/systems/parse.nix b/lib/systems/parse.nix
index fa3cc02647aed2..e3e6ef16c6b07d 100644
--- a/lib/systems/parse.nix
+++ b/lib/systems/parse.nix
@@ -416,6 +416,9 @@ rec {
     uclibceabihf = { float = "hard"; };
     uclibc       = {};
 
+    # LLVM libc
+    llvm         = {};
+
     unknown = {};
   };
 
diff --git a/pkgs/top-level/release-attrpaths-superset.nix b/pkgs/top-level/release-attrpaths-superset.nix
index 9a89062bd1749a..f27ec0cbc5b73c 100644
--- a/pkgs/top-level/release-attrpaths-superset.nix
+++ b/pkgs/top-level/release-attrpaths-superset.nix
@@ -50,6 +50,7 @@ let
 
     # cross packagesets
     pkgsLLVM = true;
+    pkgsLLVMLibc = true;
     pkgsMusl = true;
     pkgsStatic = true;
     pkgsCross = true;
@@ -190,6 +191,10 @@ let
       "pkgsLLVM"
       "stdenv"
     ]
+    [
+      "pkgsLLVMLibc"
+      "stdenv"
+    ]
     [
       "pkgsStatic"
       "stdenv"
diff --git a/pkgs/top-level/release.nix b/pkgs/top-level/release.nix
index 0140f0bd9d6a49..167e546654b5fa 100644
--- a/pkgs/top-level/release.nix
+++ b/pkgs/top-level/release.nix
@@ -341,6 +341,7 @@ let
       agdaPackages = packagePlatforms pkgs.agdaPackages;
 
       pkgsLLVM.stdenv = [ "x86_64-linux" "aarch64-linux" ];
+      pkgsLLVMLibc.stdenv = [ "x86_64-linux" "aarch64-linux" ];
       pkgsArocc.stdenv = [ "x86_64-linux" "aarch64-linux" ];
       pkgsZig.stdenv = [ "x86_64-linux" "aarch64-linux" ];
       pkgsMusl.stdenv = [ "x86_64-linux" "aarch64-linux" ];
diff --git a/pkgs/top-level/stage.nix b/pkgs/top-level/stage.nix
index 1cedd8dd184587..3b088d8507dabc 100644
--- a/pkgs/top-level/stage.nix
+++ b/pkgs/top-level/stage.nix
@@ -98,6 +98,10 @@ let
           or lib.systems.parse.abis.musl;
       });
 
+  makeLLVMParsedPlatform = parsed:
+    (parsed // {
+      abi = lib.systems.parse.abis.llvm;
+    });
 
   stdenvAdapters = self: super:
     let
@@ -207,6 +211,20 @@ let
       };
     };
 
+    pkgsLLVMLibc = nixpkgsFun {
+      overlays = [ (self': super': {
+        pkgsLLVMLibc = super';
+      })] ++ overlays;
+      # Bootstrap a cross stdenv using the LLVM toolchain and libc.
+      # This is currently not possible when compiling natively,
+      # so we don't need to check hostPlatform != buildPlatform.
+      crossSystem = stdenv.hostPlatform // {
+        config = lib.systems.parse.tripleFromSystem (makeLLVMParsedPlatform stdenv.hostPlatform.parsed);
+        useLLVM = true;
+        linker = "lld";
+      };
+    };
+
     pkgsArocc = nixpkgsFun {
       overlays = [
         (self': super': {