diff --git a/nixos/modules/module-list.nix b/nixos/modules/module-list.nix
index 92e8db5ee8e1c..14e0731a23091 100644
--- a/nixos/modules/module-list.nix
+++ b/nixos/modules/module-list.nix
@@ -654,6 +654,7 @@
   ./services/home-automation/govee2mqtt.nix
   ./services/home-automation/home-assistant.nix
   ./services/home-automation/matter-server.nix
+  ./services/home-automation/openthread-border-router.nix
   ./services/home-automation/wyoming/faster-whisper.nix
   ./services/home-automation/wyoming/openwakeword.nix
   ./services/home-automation/wyoming/piper.nix
diff --git a/nixos/modules/services/home-automation/openthread-border-router.nix b/nixos/modules/services/home-automation/openthread-border-router.nix
new file mode 100644
index 0000000000000..de23b526d1a5c
--- /dev/null
+++ b/nixos/modules/services/home-automation/openthread-border-router.nix
@@ -0,0 +1,234 @@
+{
+  lib,
+  config,
+  pkgs,
+  ...
+}:
+
+let
+  cfg = config.services.openthread-border-router;
+  logLevelMappings = {
+    "emerg" = 0;
+    "alert" = 1;
+    "crit" = 2;
+    "err" = 3;
+    "warning" = 4;
+    "notice" = 5;
+    "info" = 6;
+    "debug" = 7;
+  };
+  logLevel = lib.getAttr cfg.logLevel logLevelMappings;
+in
+{
+  meta.maintainers = with lib.maintainers; [ mrene ];
+
+  options.services.openthread-border-router = {
+    enable = lib.mkEnableOption "the OpenThread Border Router";
+
+    package = lib.mkPackageOption pkgs "openthread-border-router" { };
+
+    radioDevice = lib.mkOption {
+      type = lib.types.str;
+      default = "/dev/ttyUSB0";
+      description = "The device name of the serial port of the radio device";
+    };
+
+    backboneInterface = lib.mkOption {
+      type = lib.types.str;
+      default = "eth0";
+      description = "The network interface on which to advertise the thread ipv6 mesh prefix";
+    };
+
+    interfaceName = lib.mkOption {
+      type = lib.types.str;
+      default = "wpan0";
+      description = "The network interface to create for thread packets";
+    };
+
+    logLevel = lib.mkOption {
+      type = lib.types.enum [
+        "emerg"
+        "alert"
+        "crit"
+        "err"
+        "warning"
+        "notice"
+        "info"
+        "debug"
+      ];
+      default = "err";
+      description = "The level to use when logging messages";
+    };
+
+    rest = {
+      listenAddress = lib.mkOption {
+        type = lib.types.str;
+        default = "::";
+        description = "The address on which to listen for REST API requests";
+        example = "::";
+      };
+
+      listenPort = lib.mkOption {
+        type = lib.types.port;
+        default = 8081;
+        description = "The port on which to listen for REST API requests";
+      };
+    };
+
+    web = {
+      enable = lib.mkEnableOption "the web interface";
+      listenAddress = lib.mkOption {
+        type = lib.types.str;
+        default = "::";
+        description = "The address on which the web interface should listen";
+        example = "::";
+      };
+
+      listenPort = lib.mkOption {
+        type = lib.types.port;
+        default = 8082;
+        description = "The port on which the web interface should listen";
+      };
+    };
+
+    radio = {
+      device = lib.mkOption {
+        type = lib.types.path;
+        default = "/dev/ttyUSB0";
+        description = "The device name of the serial port of the radio device. Ignored if services.openthread-border-router.radio.url is set.";
+      };
+
+      baudRate = lib.mkOption {
+        type = lib.types.int;
+        default = 115200;
+        description = "The baud rate of the radio device. Ignored if services.openthread-border-router.radio.url is set.";
+      };
+
+      flowControl = lib.mkOption {
+        type = lib.types.bool;
+        default = false;
+        description = "Enable hardware flow control. Ignored if services.openthread-border-router.radio.url is set.";
+      };
+
+      urlQueryString = lib.mkOption {
+        type = lib.types.str;
+        default = "";
+        description = "Extra URL query string parameters. Ignored if services.openthread-border-router.radio.url is set.";
+        example = "bus-latency=100&region=ca";
+      };
+
+      url = lib.mkOption {
+        type = lib.types.nullOr lib.types.str;
+        description = "The URL of the radio device to use";
+        example = "spinel+hdlc+uart:///dev/ttyUSB0?uart-baudrate=460800&uart-flow-control";
+      };
+
+      extraDevices = lib.mkOption {
+        type = lib.types.listOf lib.types.str;
+        default = [ ];
+        description = "Extra devices to add to the radio device";
+        example = "[ \"trel://eth0\" ]";
+      };
+    };
+  };
+
+  config = lib.mkIf cfg.enable {
+    services.openthread-border-router.radio.url = lib.mkDefault (
+      "spinel+hdlc+uart://${cfg.radio.device}?"
+      + lib.concatStringsSep "&" (
+        [ "uart-baudrate=${toString cfg.radio.baudRate}" ]
+        ++ lib.optional cfg.radio.flowControl "uart-flow-control"
+        ++ lib.optional (cfg.radio.urlQueryString != "") cfg.radio.urlQueryString
+      )
+    );
+
+    # ot-ctl can be used to query the router instance
+    environment.systemPackages = [ cfg.package ];
+
+    # Make sure we have ipv6 support, and that forwarding is enabled
+    networking.enableIPv6 = true;
+    boot.kernel.sysctl = {
+      "net.ipv4.conf.all.forwarding" = 1;
+      "net.ipv6.conf.all.forwarding" = 1;
+      "net.ipv6.ip_forward" = 1;
+
+      # Make sure we accept IPv6 router advertisements from the local network interface
+      "net.ipv6.conf.${cfg.backboneInterface}.accept_ra" = 2;
+      "net.ipv6.conf.${cfg.backboneInterface}.accept_ra_rt_info_max_plen" = 64;
+    };
+
+    # OTBR needs to publish its addresses via avahi
+    services.avahi = {
+      enable = true;
+      publish = {
+        enable = true;
+        userServices = true;
+      };
+    };
+
+    # Synchronize the services with the unit files defined in the source pacakge
+    systemd.services = {
+      # Sync with: src/agent/otbr-agent.service.in
+      # Manually added otbr-firewall calls because they are handled inside platform-specific scripts
+      # The agent keeps its local state in /var/lib/thread
+      otbr-agent = {
+        description = "OpenThread Border Router Agent";
+        wantedBy = [ "multi-user.target" ];
+        requires = [ "dbus.socket" ];
+        after = [ "dbus.socket" ];
+        environment = {
+          THREAD_IF = cfg.interfaceName;
+        };
+        serviceConfig = {
+          ExecStartPre = "${lib.getExe' cfg.package "otbr-firewall"} start";
+          ExecStart = (
+            lib.concatStringsSep " " (
+              [ (lib.getExe' cfg.package "otbr-agent") ]
+              ++ [
+                "--verbose"
+                "--backbone-ifname ${cfg.backboneInterface}"
+                "--thread-ifname ${cfg.interfaceName}"
+                "--debug-level ${toString logLevel}"
+              ]
+              ++ lib.optional (cfg.rest.listenPort != 0) "--rest-listen-port ${toString cfg.rest.listenPort}"
+              ++ lib.optional (cfg.rest.listenAddress != "") "--rest-listen-address ${cfg.rest.listenAddress}"
+              ++ [ cfg.radio.url ]
+              ++ cfg.radio.extraDevices
+            )
+          );
+          ExecStopPost = "${lib.getExe' cfg.package "otbr-firewall"} stop";
+          KillMode = "mixed";
+          Restart = "on-failure";
+          RestartSec = 5;
+          RestartPreventExitStatus = "SIGKILL";
+        };
+        path = [
+          pkgs.ipset
+          pkgs.iptables
+        ];
+      };
+
+      # Sync with: src/web/otbr-web.service.in
+      otbr-web = {
+        description = "OpenThread Border Router Web";
+        after = [ "otbr-agent.service" ];
+        wantedBy = [ "multi-user.target" ];
+        serviceConfig = {
+          ExecStart = (
+            lib.concatStringsSep " " (
+              [
+                (lib.getExe' cfg.package "otbr-web")
+                "-I"
+                "${cfg.interfaceName}"
+                "-d"
+                "${toString logLevel}"
+              ]
+              ++ lib.optional (cfg.web.listenAddress != "") "-a ${cfg.web.listenAddress}"
+              ++ lib.optional (cfg.web.listenPort != 0) "-p ${toString cfg.web.listenPort}"
+            )
+          );
+        };
+      };
+    };
+  };
+}