diff --git a/pkgs/development/python-modules/django-storages/default.nix b/pkgs/development/python-modules/django-storages/default.nix
index 1014efc09e65d..161012236047f 100644
--- a/pkgs/development/python-modules/django-storages/default.nix
+++ b/pkgs/development/python-modules/django-storages/default.nix
@@ -15,6 +15,8 @@
   pythonOlder,
   rsa,
   setuptools,
+  pynacl,
+  fetchpatch,
 }:
 
 buildPythonPackage rec {
@@ -31,9 +33,19 @@ buildPythonPackage rec {
     hash = "sha256-nlM/XPot3auLzNsnHCVtog2WmiaibDRgbPOw9A5F9QI=";
   };
 
-  nativeBuildInputs = [ setuptools ];
+  patches = [
+    # Add Moto 5 support
+    # https://github.com/jschneier/django-storages/pull/1464
+    (fetchpatch {
+      url = "https://github.com/jschneier/django-storages/commit/e1aedcf2d137f164101d31f2f430f1594eedd78c.patch";
+      hash = "sha256-jSb/uJ0RXvPsXl+WUAzAgDvJl9Y3ad2F30X1SbsCc04=";
+      name = "add_moto_5_support.patch";
+    })
+  ];
+
+  build-system = [ setuptools ];
 
-  propagatedBuildInputs = [ django ];
+  dependencies = [ django ];
 
   optional-dependencies = {
     azure = [ azure-storage-blob ];
@@ -52,26 +64,24 @@ buildPythonPackage rec {
     rsa
   ] ++ lib.flatten (builtins.attrValues optional-dependencies);
 
+  checkInputs = [ pynacl ];
+
   pythonImportsCheck = [ "storages" ];
 
   env.DJANGO_SETTINGS_MODULE = "tests.settings";
 
   disabledTests = [
     # AttributeError: 'str' object has no attribute 'universe_domain'
+    # https://github.com/jschneier/django-storages/issues/1463
     "test_storage_save_gzip"
   ];
 
-  disabledTestPaths = [
-    # ImportError: cannot import name 'mock_s3' from 'moto'
-    "tests/test_s3.py"
-  ];
-
-  meta = with lib; {
+  meta = {
     description = "Collection of custom storage backends for Django";
     changelog = "https://github.com/jschneier/django-storages/blob/${version}/CHANGELOG.rst";
     downloadPage = "https://github.com/jschneier/django-storages/";
     homepage = "https://django-storages.readthedocs.io";
-    license = licenses.bsd3;
-    maintainers = with maintainers; [ mmai ];
+    license = lib.licenses.bsd3;
+    maintainers = with lib.maintainers; [ mmai ];
   };
 }