diff --git a/avogadro/qtplugins/CMakeLists.txt b/avogadro/qtplugins/CMakeLists.txt
index 1c968bc12e..b2c5219a9d 100644
--- a/avogadro/qtplugins/CMakeLists.txt
+++ b/avogadro/qtplugins/CMakeLists.txt
@@ -156,7 +156,9 @@ if(USE_VTK)
   add_subdirectory(plotpdf)
   add_subdirectory(plotrmsd)
   add_subdirectory(plotxrd)
-  add_subdirectory(yaehmop)
+  if(USE_SPGLIB)
+    add_subdirectory(yaehmop)
+  endif()
 endif()
 
 # script plugins (input generators, etc.)