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fitting LMM with given kinship matrix #47

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GuoanQi1996 opened this issue Apr 12, 2024 · 1 comment
Open

fitting LMM with given kinship matrix #47

GuoanQi1996 opened this issue Apr 12, 2024 · 1 comment

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@GuoanQi1996
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GuoanQi1996 commented Apr 12, 2024

Hi. Is there any detailed documetation about the parameters used in Metida? Like, if I have a kinship matrix, which commonly used in genetic studies reflects the pairwised genetic relatedness, and i want to include it into LMM as a random effect, how could I possibly do it?

@PharmCat
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Hi. Is there any detailed documetation about the parameters used in Metida? Like, if I have a kinship matrix, which commonly used in genetic studies reflects the pairwised genetic relatedness, and i want to include it into LMM as a random effect, how could I possibly do it?

Hi! Sorry for la-a-a-a-a-a-a-te reply... All documentation here: https://pharmcat.github.io/Metida.jl/stable/

Unfortunately I don't know what is kinship matrix exactly. If you try to clarify what you want - maybe I can help to fit LMM with Metida (or something else). Basically Metida can fit any structure of random effect, but you should have tabulated data to fit the model.

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