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Pumas Bayesian Workshop

These are the slides and code for the Pumas Bayesian Workshop.

Double your think time!

Outline

  • Participants introduction
  • Why Bayesian?
  • Introduction to probability and Bayesian statistics
  • Hands on: getting started with Pumas on the cloud
  • Bayesian PK model
  • Hands-on
    • Pumas Data Representation (NMTRAN datasets and Population)
    • Pumas model macro and dynamics block
    • Bayesian PK model in Pumas
  • Bayesian Logistic Regression
  • Hands-on: Bayesian logistic regression in Pumas
  • Hierarchical Models in Pumas
  • Bayesian PopPK Model
  • Hands-on: population PK models
  • Bayesian PKPD model
  • Hands-on: population PKPD models
  • Posterior predictions and simulations
  • MCMC, marginal MCMC and NUTS
  • Convergence diagnostics
  • What to do if MCMC fails?
  • Hands-on: diagnostics, simulations, post-processing and plots
  • Crossvalidation and model evaluation
  • Hands-on: cross-validation