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Update README.md
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RJWANGbioinfo committed Feb 28, 2022
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Expand Up @@ -281,8 +281,8 @@ The output contains 4 columns: ‘gene symbol’ describes gene information;
statistical significance based on the Fisher’s exact test; ‘p_adj’ is FDR
adjusted pvalue and ‘APAreg’ is 3’UTR APA regulation pattern in the gene.
We define 3 types in ‘APAreg’, ‘UP’ means aUTR abundance in the treatment group
(‘KD’ in this case) is at least 5% higher than that in control
(‘NT’ in this case), and ‘pvalue’<0.05; ‘DN’ means aUTR abundance is 5% lower
(‘KD’ in this case) is at least 5% lower than that in control
(‘NT’ in this case), and ‘pvalue’<0.05; ‘DN’ means aUTR abundance is 5% higher
in treatment than that in control and p-value<0.05; ‘NC’ are the remaining
genes. With respect to 3’UTR size changes,
‘UP’ means 3’UTR shortening, and ‘DN’ 3’UTR lengthening.
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