diff --git a/src/initialization.jl b/src/initialization.jl
index 9f5274eae..eea553005 100644
--- a/src/initialization.jl
+++ b/src/initialization.jl
@@ -225,3 +225,15 @@ function get_initial_values(prob, valp, f, alg::OverrideInit,
 
     return u0, p, success
 end
+
+function is_trivial_initialization(initdata::OverrideInitData)
+    state_values(initdata.initializeprob) === nothing
+end
+
+function is_trivial_initialization(f::AbstractSciMLFunction)
+    has_initialization_data(f) && is_trivial_initialization(f.initialization_data)
+end
+
+function is_trivial_initialization(prob::AbstractSciMLProblem)
+    is_trivial_initialization(prob.f)
+end
diff --git a/src/remake.jl b/src/remake.jl
index 280957671..d008c2e3f 100644
--- a/src/remake.jl
+++ b/src/remake.jl
@@ -114,6 +114,7 @@ function remake(prob::ODEProblem; f = missing,
         interpret_symbolicmap = true,
         build_initializeprob = true,
         use_defaults = false,
+        lazy_initialization = !is_trivial_initialization(prob),
         _kwargs...)
     if tspan === missing
         tspan = prob.tspan
@@ -170,13 +171,21 @@ function remake(prob::ODEProblem; f = missing,
         _f = ODEFunction{isinplace(prob), specialization(prob.f)}(f)
     end
 
-    if kwargs === missing
+    prob = if kwargs === missing
         ODEProblem{isinplace(prob)}(
             _f, newu0, tspan, newp, prob.problem_type; prob.kwargs...,
             _kwargs...)
     else
         ODEProblem{isinplace(prob)}(_f, newu0, tspan, newp, prob.problem_type; kwargs...)
     end
+
+    if !lazy_initialization
+        u0, p, _ = get_initial_values(prob, prob, prob.f, OverrideInit(), Val(isinplace(prob)))
+        @reset prob.u0 = u0
+        @reset prob.p = p
+    end
+
+    return prob
 end
 
 """
diff --git a/test/downstream/modelingtoolkit_remake.jl b/test/downstream/modelingtoolkit_remake.jl
index 228a26dd6..6029a06ab 100644
--- a/test/downstream/modelingtoolkit_remake.jl
+++ b/test/downstream/modelingtoolkit_remake.jl
@@ -274,3 +274,12 @@ end
     @test_throws SciMLBase.CyclicDependencyError remake(
         prob; u0 = [x => 2y + p, y => q + 3], p = [p => x + y, q => p + 3])
 end
+
+@testset "Lazy initialization" begin
+    @variables x(t) [guess = 1.0] y(t) [guess = 1.0]
+    @parameters p = missing [guess = 1.0]
+    @mtkbuild sys = ODESystem([D(x) ~ x, x + y ~ p], t)
+    prob = ODEProblem(sys, [x => 1.0, y => 1.0], (0.0, 1.0))
+    prob2 = remake(prob; u0 = [x => 2.0])
+    @test prob2.ps[p] ≈ 3.0
+end