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$aesinit.html
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<HTML><HEAD> <TITLE> $aesinit.ctl</TITLE><HEAD>
<BODY BGCOLOR="#FFFFFF">
<PRE>
+--------------------------------------------------------------------+
| |
| $AESINITIAL |
| |
+--------------------------------------------------------------------+
MEANING: Marks the beginning of abbreviated code for the AES routine
CONTEXT: NM-TRAN Control Record
USAGE:
$AESINITIAL
abbreviated code
DISCUSSION:
The $AESINITIAL record is used to compute the amounts in the equilib-
rium compartments at the beginning of an integration interval. It is
used with PREDPP's ADVAN9, ADVAN15, and ADVAN17. May also be coded
$AES0.
(See <A HREF="$.html#$aes">$AES</A>).
General rules for abbreviated code are documented elsewhere
(See <A HREF="a.html#abbreviated_code">abbreviated code</A>).
Specific rules follow.
ASSIGNMENT AND CONDITIONAL STATEMENTS
Left-hand quantities in assignment statements:
A(ncm1+1), A(ncm1+2), ... (Required. The amounts in the equilibrium
compartments at the beginning of the integration interval. ncm1 is the
number of nonequilibrium compartments.)
INIT (Initialization flag.)
INIT=0: The A(n) are approximate.
INIT=1: The A(n) are exact (the default).
AESINITIAL-defined (i.e., PRED-defined) items.
Right-hand quantities in assignment statement and in conditions:
A(1), A(2), ... (Current compartment amounts; may be random vari-
ables.)
P(1), P(2), ... (Post-translation basic PK parameters; may be ran-
dom variables.)
PK-defined items (Implicit basic PK parameters; may be random vari-
ables.)
T (Time at the beginning of the integration interval; may be random
variables.)
AESINITIAL-defined items that appeared earlier as left-hand quanti-
ties.
Data item labels specified on the $INPUT statement.
THETA(n).
Global Variables in Modules
Certain variables in FORTRAN Modules can be used.
(See <A HREF="v.html#variables_in_modules">Variables_in_modules</A>)
Forbidden Variable Names:
IR DA DP DT E(n) ETA(n) EPS(n) ERR(n)
PSEUDO ASSIGNMENT STATEMENTS
COMRES=-1
CALLFL=-1: Call ADVAN and AES with every event record (default).
CALLFL=1: Call ADVAN and AES once per individual record.
(CALLFL may be used only when the TIME data item is not defined.) The
pseudo assignments statements may be enclosed in parentheses. If both
are present within the same set of parentheses, separate them with a
semicolon. Within parentheses, a calling protocol phrase may be used
instead of CALLFL, and either upper or lower case may be used. E.g.,
$AESINIT (ONCE PER IR) ; same as CALLFL=1
$AESINIT (EVERY EVENT) ; same as CALLFL=-1 (default)
(See <A HREF="c.html#calling_protocol_phrase">calling protocol</A>).
RECORD ORDER:
Follows $SUBROUTINES $INPUT $MODEL $PK
Precedes $AES
REFERENCES: Guide IV Section <a href="IV/V.html#C.8.">V.C.8<a/>
REFERENCES: Guide VI Section <a href="VI/VI.html#E.">VI.E<a/>
<pre>Go to <A HREF=index.html>main index</A>.</pre>
<pre>
<hr ALIGN=LEFT WIDTH="450"></pre>
<i><font size=-1>Created by nmhelp2html v. 1.0 written by Niclas Jonsson (Modified by AJB 5/2006,11/2007,10/2012)</font>
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