diff --git a/data/QALY_model/interim/long_COVID/average_QALY_losses_per_age.csv b/data/QALY_model/interim/long_COVID/average_QALY_losses_per_age.csv deleted file mode 100644 index fe0c1f79a..000000000 --- a/data/QALY_model/interim/long_COVID/average_QALY_losses_per_age.csv +++ /dev/null @@ -1,425 +0,0 @@ -hospitalisation,age,mean,sd,lower,upper -Non-hospitalised,0,0.8215390373308605,0.29465763266328043,0.28036124200002444,1.3797523076334535 -Non-hospitalised,1,0.810249580714112,0.29039818992861366,0.2769852774180494,1.3604003061293022 -Non-hospitalised,2,0.7981948554741376,0.285841919474182,0.27336024506043904,1.3397172228972618 -Non-hospitalised,3,0.7861726683690834,0.2812976613337425,0.26974367302420305,1.3190924627289895 -Non-hospitalised,4,0.7742310181904402,0.276783850148402,0.2661507395802473,1.2986074017144333 -Non-hospitalised,5,0.7623597824208911,0.27229641074371363,0.2625778752224441,1.2782420165438027 -Non-hospitalised,6,0.7505922324068292,0.26784813880903346,0.2590356229257264,1.2580539885393545 -Non-hospitalised,7,0.7389196539971072,0.2634355489131123,0.2555209651842476,1.2380278926619026 -Non-hospitalised,8,0.7273542025615221,0.259063273581703,0.25203767740157956,1.218184709131199 -Non-hospitalised,9,0.7159051930829388,0.2547348558457339,0.24858864057367006,1.1985405009581087 -Non-hospitalised,10,0.704568700036771,0.2504487039642586,0.24517247189117855,1.1790882910847285 -Non-hospitalised,11,0.6933479110049804,0.24620599839128626,0.2417901124386,1.1598335208408852 -Non-hospitalised,12,0.6822595958667521,0.24201320806696178,0.23844691263031265,1.140805310123417 -Non-hospitalised,13,0.6712855507910495,0.23786321376135258,0.23513692718204116,1.1219718783957662 -Non-hospitalised,14,0.6604554956016628,0.23376753369291944,0.23186971738301207,1.10338493008675 -Non-hospitalised,15,0.6497375691042816,0.22971375050461335,0.22863495739734038,1.0849889390772687 -Non-hospitalised,16,0.6391690977596199,0.2257163523277481,0.22544467946264515,1.0668488728915135 -Non-hospitalised,17,0.6287199619089534,0.22176360952483382,0.2222891510867207,1.0489122747100692 -Non-hospitalised,18,0.6184072718800155,0.21786216044036844,0.21917389236395854,1.031208929548278 -Non-hospitalised,19,0.6082509363286763,0.2140197339549186,0.21610531778646627,1.0137734845239275 -Non-hospitalised,20,0.598200152231286,0.2102165763688773,0.21306708176341793,0.9965175450927654 -Non-hospitalised,21,0.5882756723827264,0.2064607556955396,0.21006589820754556,0.9794772599247389 -Non-hospitalised,22,0.5785078412994047,0.20276406566922078,0.20711154608006413,0.9627054419513457 -Non-hospitalised,23,0.5688423364657366,0.1991054066250663,0.20418660929655075,0.9461076457203343 -Non-hospitalised,24,0.559299452502155,0.1954926778626316,0.20129765905211638,0.9297192286101269 -Non-hospitalised,25,0.5498785228893656,0.1919256370900449,0.19844453421813824,0.9135390915604021 -Non-hospitalised,26,0.5405653281882314,0.1883987861595056,0.19562274317967335,0.8975425899679833 -Non-hospitalised,27,0.5313920257941709,0.18492462748434868,0.19284263386094147,0.8817856748317611 -Non-hospitalised,28,0.5223203972698036,0.1814883584027685,0.19009205143212551,0.8662020138746829 -Non-hospitalised,29,0.5133651678985742,0.1780957221096589,0.18737577383266538,0.8508172732403577 -Non-hospitalised,30,0.504521799341788,0.17474499095773946,0.18469242488322107,0.8356236534864001 -Non-hospitalised,31,0.4957973572704282,0.17143893481701297,0.18204432492666953,0.8206335018920143 -Non-hospitalised,32,0.48716238573097215,0.1681661843613463,0.17939377719391136,0.8057957857426612 -Non-hospitalised,33,0.47862334494482295,0.1649292868911291,0.17675354775773436,0.7911218246594802 -Non-hospitalised,34,0.4701890260689875,0.1617316860536543,0.17414676953091013,0.776626966349164 -Non-hospitalised,35,0.4618373685210375,0.1585648973442301,0.1715669232946057,0.7622730547589391 -Non-hospitalised,36,0.4535833572093073,0.155434760235213,0.16901822859732585,0.7480861768957078 -Non-hospitalised,37,0.44540930948113655,0.1523344927312203,0.16649541316375474,0.7340357867203892 -Non-hospitalised,38,0.43733100049974966,0.14927023198289396,0.16400295074401017,0.7201493213119681 -Non-hospitalised,39,0.4293281995354428,0.14623422028009536,0.16153480875983017,0.7063918334141682 -Non-hospitalised,40,0.4214224334707542,0.1432348026790002,0.15909717271329082,0.6928006985199666 -Non-hospitalised,41,0.4135860735160336,0.14026137772728842,0.1566818242978751,0.6793281732947786 -Non-hospitalised,42,0.4058014658770356,0.1373072053472055,0.15428342724158417,0.6659438204324394 -Non-hospitalised,43,0.39811088562422303,0.13438860300398603,0.15191431258083338,0.6527208900038631 -Non-hospitalised,44,0.390460410151424,0.13148487872982212,0.149558447784905,0.6395661966249212 -Non-hospitalised,45,0.3828775544216494,0.12860666389251516,0.1472238316247107,0.626527437341959 -Non-hospitalised,46,0.37538356567990244,0.1257621555057488,0.14491667174133224,0.6136414190496952 -Non-hospitalised,47,0.3679168179491672,0.12292773840486991,0.14261856474817317,0.6008017091694056 -Non-hospitalised,48,0.3605119432856676,0.12011675236057387,0.14033968122711746,0.5880682588416734 -Non-hospitalised,49,0.3531379616026996,0.11731736315277197,0.1380706765317534,0.5753876386072225 -Non-hospitalised,50,0.3458385656403181,0.1145463553642724,0.13582449286245354,0.5628353946963154 -Non-hospitalised,51,0.3385618545904483,0.11178388612546244,0.13358551764958249,0.550321982563712 -Non-hospitalised,52,0.33135481922366394,0.10904798141564866,0.13136773176880925,0.5379286007722702 -Non-hospitalised,53,0.3241749003208389,0.10632238793707893,0.12915828661098816,0.5255818592343968 -Non-hospitalised,54,0.31704325670912287,0.10361523209026473,0.12696345028274256,0.5133183417201846 -Non-hospitalised,55,0.3099551815911332,0.1009247413296398,0.12478173544090514,0.501129985486209 -Non-hospitalised,56,0.3028779702004582,0.0982384548509314,0.12260319352244585,0.48896045449766096 -Non-hospitalised,57,0.29582956476274375,0.09556325897401566,0.12043314855159899,0.47684076385310425 -Non-hospitalised,58,0.28881191908110476,0.09289992572273993,0.11827211919644792,0.46477434040520327 -Non-hospitalised,59,0.2818361148344583,0.09025270310541998,0.1161234037259792,0.45278033193629663 -Non-hospitalised,60,0.27484680394061467,0.08760051314867955,0.11397014017168997,0.4407634185486647 -Non-hospitalised,61,0.26794380858012273,0.08498142150581658,0.11184259326643163,0.42889563156866717 -Non-hospitalised,62,0.2610917353145221,0.08238194136308324,0.10972999940014931,0.41711600127070186 -Non-hospitalised,63,0.25432520161373046,0.079815256335934,0.1076428965507532,0.4054841522054895 -Non-hospitalised,64,0.247586218898992,0.07725929159838732,0.10556359741017085,0.39390023399428786 -Non-hospitalised,65,0.2408863488939791,0.07471845931246644,0.10349559690834549,0.38238418027738297 -Non-hospitalised,66,0.2342277461649845,0.07219358738553895,0.10143953091867877,0.37093971822823135 -Non-hospitalised,67,0.22752822469347891,0.06965344011174374,0.09937020214209752,0.35942543693161805 -Non-hospitalised,68,0.22092827133882642,0.06715144264973379,0.09733060282400066,0.34808312520745227 -Non-hospitalised,69,0.2141929206147025,0.06459831444866929,0.09524864170971621,0.3365085401691877 -Non-hospitalised,70,0.2075883277837957,0.06209520765338958,0.09320594159770919,0.325159615422559 -Non-hospitalised,71,0.20103976239484728,0.059613724412468,0.09117959243420541,0.31390776707284707 -Non-hospitalised,72,0.1944783171733291,0.0571277123157421,0.08914838825088399,0.3026344965636937 -Non-hospitalised,73,0.18800229636620622,0.05467450214092357,0.08714257866195978,0.29150885836952317 -Non-hospitalised,74,0.1815540843840758,0.05223223445022761,0.08514443057022125,0.2804317737372173 -Non-hospitalised,75,0.17519820704003888,0.0498254006192376,0.08317385624070082,0.2695141621146458 -Non-hospitalised,76,0.16884053797190265,0.04741831487325376,0.08120181812352226,0.25859421332379123 -Non-hospitalised,77,0.1623966392309089,0.0449790091537707,0.07920218081597095,0.24752684256718743 -Non-hospitalised,78,0.15622095215118487,0.04264186571279184,0.07728454129997278,0.23692115506720438 -Non-hospitalised,79,0.14991068962779747,0.04025426351717106,0.0753243342380585,0.226084979313972 -Non-hospitalised,80,0.14378937109095363,0.037938828949273994,0.07342170829500086,0.2155741897595765 -Non-hospitalised,81,0.13780366998374308,0.03567538096786722,0.07156023385145904,0.20529709676524885 -Non-hospitalised,82,0.1318268133144025,0.03341598511448448,0.0697006398907472,0.19503589965289256 -Non-hospitalised,83,0.12601593000617897,0.031220188606581146,0.0678917076680402,0.18506046509950685 -Non-hospitalised,84,0.1204662387515517,0.02912405113942511,0.06616310372339515,0.17553424426075548 -Non-hospitalised,85,0.11499292647383268,0.0270577611134951,0.06445750304738462,0.16613978200304064 -Non-hospitalised,86,0.10983067601930302,0.025110101241605298,0.06284792671356508,0.15728001067681757 -Non-hospitalised,87,0.10491181845750684,0.0232555524783403,0.06131345411161404,0.1488386389154069 -Non-hospitalised,88,0.10036913608228248,0.021544257640149042,0.05989551932563392,0.14104354705962574 -Non-hospitalised,89,0.09612443047250667,0.019946708017952546,0.05856990794796159,0.1337603796673272 -Non-hospitalised,90,0.09200616960066314,0.01839837064692916,0.05728327629875338,0.12669460662955054 -Non-hospitalised,91,0.08840992877601823,0.017048140044741235,0.056123355923305286,0.12052283661702154 -Non-hospitalised,92,0.08509828260039594,0.015806554908086853,0.05504671819333304,0.11479637556570743 -Non-hospitalised,93,0.08169343976287013,0.014532026312261572,0.05393948350208276,0.10890828375675707 -Non-hospitalised,94,0.0785673878910018,0.013364364548968444,0.0529222268477569,0.10350217089774663 -Non-hospitalised,95,0.0758705453625101,0.012359605159546915,0.05204383529605412,0.09883846172266919 -Non-hospitalised,96,0.07348176786679582,0.011472120796686226,0.051262631030770466,0.09470769769527977 -Non-hospitalised,97,0.07134359864680294,0.010680244223530581,0.050557306874158776,0.09101059553458023 -Non-hospitalised,98,0.0694559412908773,0.00998365148768083,0.0499338748182454,0.08774713947399093 -Non-hospitalised,99,0.06740964899695494,0.00923145729557726,0.04925774329907314,0.08422707995557979 -Non-hospitalised,100,0.06608122861709463,0.008746019463868774,0.0488170521652858,0.08204061446506078 -Non-hospitalised,101,0.06349814663050812,0.0078071286548533755,0.048063465387941144,0.07778832720880326 -Non-hospitalised,102,0.061633094600094786,0.007137742351746698,0.04761806121273492,0.07462547382567204 -Non-hospitalised,103,0.05821378280490502,0.005939419359532592,0.04662975609626849,0.06898462239083715 -Non-hospitalised,104,0.05311435366572785,0.004318582116959235,0.0448510807525614,0.06162076593508076 -Non-hospitalised,105,0.04206999186763898,0.0023423025213870114,0.03782041704658469,0.04660198148526385 -Cohort,0,2.1109592359388683,0.9573039559566742,0.5826490213148227,3.9016252326650354 -Cohort,1,2.0846751453417154,0.9456313379056966,0.5759744074327631,3.8550329756897628 -Cohort,2,2.0549959507678124,0.9321309725703107,0.5684590656723775,3.801034115709317 -Cohort,3,2.0252999576516686,0.9186056805455942,0.5609405290390753,3.7469258724949492 -Cohort,4,1.9957636109575103,0.9051466835601342,0.5534627646504601,3.693076683930409 -Cohort,5,1.9663187081841949,0.8917146895203816,0.5460090702358529,3.639327238790562 -Cohort,6,1.9370897885294895,0.8783743851734922,0.5386104512117379,3.585938807943071 -Cohort,7,1.9080229446701185,0.865095012980713,0.5312536788189423,3.5327869016292572 -Cohort,8,1.8791573886684052,0.8518961080435611,0.523948571049719,3.4799504170813256 -Cohort,9,1.8505221724509509,0.8387919886555083,0.5167024121234427,3.427487189179358 -Cohort,10,1.8220910857791746,0.8257674930719923,0.5095087801776805,3.3753360659265668 -Cohort,11,1.793870352191352,0.8128250586034095,0.5023692757117838,3.323507047832017 -Cohort,12,1.7659258223417404,0.7999992860485063,0.4953002643006312,3.2721399314188573 -Cohort,13,1.7381745862580587,0.7872450547027167,0.4882812390859978,3.221052871797392 -Cohort,14,1.7107399096023856,0.7746280173492553,0.4813427786771932,3.1705109036213375 -Cohort,15,1.6834832658139813,0.7620734875190732,0.4744505722149135,3.120213096944752 -Cohort,16,1.6565614508768056,0.7496652608813339,0.4676435000078387,3.0704975375057146 -Cohort,17,1.6298458532393614,0.7373342236794079,0.4608896899005634,3.0210859141012794 -Cohort,18,1.6034086688470848,0.725118969643949,0.45420704256412914,2.9721340496524364 -Cohort,19,1.577333251629283,0.7130640318363778,0.4476162296074043,2.92382154149705 -Cohort,20,1.5514084207780028,0.7010565403550623,0.4410648730504166,2.875694099033964 -Cohort,21,1.5257232876578677,0.6891443471637283,0.43457505540931557,2.827944788659531 -Cohort,22,1.500405134151319,0.677395547264305,0.42817833935469274,2.780847969121763 -Cohort,23,1.4752331457811705,0.6656926494813022,0.4218199196567176,2.7339310340362197 -Cohort,24,1.45029492282973,0.6540827822723286,0.41552150080924066,2.6873839888750095 -Cohort,25,1.425591921217893,0.6425671597404542,0.4092834132942347,2.641212002352794 -Cohort,26,1.4010717039323788,0.6311184656624579,0.40309260203537245,2.595305487384723 -Cohort,27,1.3768679551981733,0.6198081461194253,0.3969822258234029,2.549952029153434 -Cohort,28,1.3528332118296884,0.6085586267915897,0.39091562445452155,2.5048399028142145 -Cohort,29,1.3290318403811177,0.5974046631290039,0.3849087400461826,2.460109093814503 -Cohort,30,1.3054516897158877,0.5863405080467775,0.3789585091665342,2.4157366984280935 -Cohort,31,1.2821258538596105,0.5753842754056974,0.37307311301499535,2.371795702387016 -Cohort,32,1.2589469702971172,0.5644802646999062,0.36722580986972014,2.3280624168899675 -Cohort,33,1.235947388606476,0.5536464054178332,0.36142458291478446,2.2846090804122205 -Cohort,34,1.2131672472549826,0.5429045812643141,0.35567936145188844,2.2415237708847737 -Cohort,35,1.1905305587940145,0.5322159624180263,0.34997118091893414,2.1986505986447367 -Cohort,36,1.1681006316399825,0.5216145389669897,0.3443157367721894,2.1561262428302514 -Cohort,37,1.1458191742285595,0.5110708992330136,0.33869845730616077,2.1138326388183195 -Cohort,38,1.1237510616840658,0.5006196787149009,0.33313543941259705,2.0719090079209797 -Cohort,39,1.1018296295563732,0.49022725219123103,0.32761001795054917,2.0302203433536214 -Cohort,40,1.0801388969096068,0.47993794501621134,0.32214307382244384,1.9889447521392614 -Cohort,41,1.0585866794792127,0.46970509510959974,0.3167115728659061,1.9478948514992425 -Cohort,42,1.0371188317068485,0.4595019992394979,0.3113019414059486,1.9069634360531176 -Cohort,43,1.0158900689721901,0.4494089889382976,0.30595271188516165,1.8664731992999886 -Cohort,44,0.994720067834006,0.43933473488157987,0.300618830027346,1.8260573526103003 -Cohort,45,0.9737110355063819,0.42933251050996224,0.29532573817860097,1.785929898466281 -Cohort,46,0.9529401724687594,0.41944232377490537,0.29009266835226477,1.7462515498229634 -Cohort,47,0.9322058835423843,0.40956273935327075,0.2848692095115763,1.7066149395223082 -Cohort,48,0.9116310650112264,0.3997570462868545,0.2796860022463032,1.6672742889018262 -Cohort,49,0.8911195756669013,0.3899776571447156,0.2745189559966026,1.6280385100332802 -Cohort,50,0.8708202769241786,0.38030036441378706,0.26940523927404886,1.5892120419248745 -Cohort,51,0.8505697216730774,0.37064388609188625,0.2643039200133498,1.5504684832963587 -Cohort,52,0.8305245564121887,0.36108747228517646,0.259254142099856,1.5121261650996234 -Cohort,53,0.8105533308109701,0.35156615520188733,0.2542229609406009,1.4739242231595264 -Cohort,54,0.7907281013561739,0.34211660812004235,0.24922836842089732,1.436010002712291 -Cohort,55,0.7710380465948953,0.33273406736528305,0.2442676151890034,1.3983644388870555 -Cohort,56,0.7513863439447492,0.32337134434570797,0.23930156360798657,1.3607981048593791 -Cohort,57,0.7318336047803936,0.3140592082785574,0.23430619288011473,1.3234346534127261 -Cohort,58,0.7123898501053612,0.30480323287751215,0.22933671528254165,1.2862965569597677 -Cohort,59,0.6930919612697113,0.2956220512194034,0.22440205332030946,1.249458728199507 -Cohort,60,0.6737774935728171,0.2864367272533515,0.2194614498397292,1.2126043116689231 -Cohort,61,0.6547476257120742,0.27739493911768626,0.2145898470679814,1.1763263694575101 -Cohort,62,0.6358974148276509,0.26844550856330496,0.20976099598742853,1.1404194794030322 -Cohort,63,0.6173289432957002,0.25963809790811343,0.20500047271510682,1.1050830860644183 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-Cohort,86,0.23293722329253225,0.07953984404625641,0.10524512976394278,0.3824292632929682 -Cohort,87,0.22034133304968503,0.07374612289770281,0.10192201140707913,0.3591288758563814 -Cohort,88,0.20874058612497287,0.06842131086622323,0.0988580745638195,0.3377337365496325 -Cohort,89,0.19792729999693504,0.06346864157725325,0.0959992985524287,0.31803924187260846 -Cohort,90,0.18745864811350946,0.058684654789261916,0.09322933501729376,0.2990110866470877 -Cohort,91,0.17833882736614765,0.054528206896980624,0.09081361747595876,0.28245765135546136 -Cohort,92,0.16995677712674362,0.05071820487795464,0.08859140998095401,0.26725981546034905 -Cohort,93,0.16135142063660052,0.04681778584354298,0.08630882416933058,0.25167013456332843 -Cohort,94,0.1534650873822014,0.04325623199623116,0.08408960638654624,0.23739812185031003 -Cohort,95,0.1466737534723419,0.04020173571182653,0.08194159390833738,0.2251208076276278 -Cohort,96,0.14066697378022877,0.03751178164100134,0.08073012797904137,0.21427176311204893 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-ICU,38,1.7336665663616984,0.6567122899867329,0.5562690010140071,2.873152927253137 -ICU,39,1.6989296543226546,0.6430487535118012,0.5459057275813489,2.8145458793232714 -ICU,40,1.6645637133666906,0.6295179534001016,0.535653275220738,2.756524422503991 -ICU,41,1.6304251455966194,0.6160572199453627,0.5254689040416722,2.6988273760041035 -ICU,42,1.5964290161437122,0.602630999607059,0.515327312428498,2.6413048122136717 -ICU,43,1.5628146310755744,0.5893480687833208,0.5052996639195566,2.584405073192938 -ICU,44,1.5293011472238112,0.5760857424716344,0.49530237105133945,2.527616959486887 -ICU,45,1.4960464825523296,0.5629162434022352,0.48538238826111907,2.471237659305351 -ICU,46,1.4631701099345105,0.5498937095773656,0.4755752462462367,2.4154905151677295 -ICU,47,1.4303575007005527,0.5368821718760829,0.4657873108632113,2.3598073015635905 -ICU,48,1.3977991802554763,0.5239671002899865,0.4560752559283744,2.3045415869406543 -ICU,49,1.365344489980321,0.5110850498188182,0.44639420640782485,2.2494262657494546 -ICU,50,1.3332249314131486,0.49833800037026776,0.43681305195959336,2.1948853505802384 -ICU,51,1.301184692229258,0.4856174154925237,0.4272556081893818,2.1404628688856895 -ICU,52,1.2694678006505038,0.47302970521370735,0.4177945080962772,2.0866025351662283 -ICU,53,1.2378681835472365,0.46048829284846493,0.408368367714035,2.032939637478222 -ICU,54,1.2064979030927137,0.448042509087842,0.3990105344709311,1.9796793965010868 -ICU,55,1.1753394957917924,0.43568625672328276,0.38971578811631674,1.926794724663835 -ICU,56,1.1442406118246538,0.4233569416180547,0.380438726664505,1.8740202977679343 -ICU,57,1.113295573630636,0.41109591168463067,0.37120742081136865,1.8215283882353313 -ICU,58,1.0825195559049487,0.3989108545221115,0.36202637106933777,1.7693499499079253 -ICU,59,1.0519700206308646,0.3868267611690566,0.3529126809396508,1.7175894080719254 -ICU,60,1.0213911644447808,0.374739027998324,0.3437901106228139,1.6658027792522898 -ICU,61,0.9912560975209448,0.36284389309206316,0.33479962388969664,1.6148200486129811 -ICU,62,0.961399715371353,0.3510734420995161,0.32589201850182214,1.5643535076380306 -ICU,63,0.9319826996788482,0.33949347457507184,0.3171151819052837,1.5146825611087134 -ICU,64,0.9027387150562983,0.32799548226002795,0.308389729220345,1.4653462012047413 -ICU,65,0.8737234041307198,0.31660269859433476,0.2997322363766216,1.4164426624055906 -ICU,66,0.8449483801389642,0.305320222892751,0.29114615873053107,1.3679933450426593 -ICU,67,0.8160465285048037,0.29400104431164226,0.28252203478772603,1.3193706275307484 -ICU,68,0.7876517766300809,0.2829004831350002,0.2740488572021394,1.2716632439090572 -ICU,69,0.7587188250316734,0.27160110225346723,0.26541493570172997,1.2230874541783896 -ICU,70,0.7304347932067441,0.26057762822049246,0.2569742375604374,1.1756713980737934 -ICU,71,0.7024657533823115,0.2496963059736741,0.24862719693598956,1.128844100034679 -ICU,72,0.6745102934284791,0.23883801913354172,0.24028391859703718,1.0820952282571408 -ICU,73,0.6469986914642151,0.22817277224459506,0.2320727309149109,1.036153524309092 -ICU,74,0.6196790968941701,0.21760108114417637,0.22391851959592948,0.9905927056106607 -ICU,75,0.592829398737976,0.2072315959841317,0.2159041811922538,0.9458798184029484 -ICU,76,0.5660435116788716,0.19690530103015247,0.20790858027284073,0.901331780266286 -ICU,77,0.5389640894386964,0.1864840419833057,0.1998250932325681,0.8563530782980868 -ICU,78,0.5131000361582162,0.17655346765982344,0.19210390638842414,0.8134655738804437 -ICU,79,0.4867382007817616,0.1664490994355415,0.18423388977418195,0.7698073226510415 -ICU,80,0.4612467975840336,0.15669969484807308,0.1766232902140073,0.7276576675857767 -ICU,81,0.4363940538031199,0.14721415465349888,0.16920297649324254,0.6866253656865154 -ICU,82,0.4116460141195492,0.137786840715763,0.16181361885175993,0.6458226832171595 -ICU,83,0.38765596247222234,0.1286674304935994,0.15465018845675477,0.6063287174776496 -ICU,84,0.364811336141263,0.1200018439291317,0.14782834933976796,0.5687763865173018 -ICU,85,0.34233969406512815,0.1114942517011578,0.1411175848010615,0.5318863823495149 -ICU,86,0.3212037129988957,0.10350907933203282,0.13480525635394833,0.4972379643214899 -ICU,87,0.3011150598854247,0.09593463575260637,0.1288053400623785,0.46434902617358165 -ICU,88,0.28260887560557646,0.08897094082425652,0.12327761601824438,0.43408938963813154 -ICU,89,0.26535504044053726,0.0824908365094184,0.11812358107728047,0.40590958748067973 -ICU,90,0.24864767888328265,0.07622726703034442,0.11313253885874656,0.378649739667356 -ICU,91,0.23409024901379452,0.07078092725357613,0.1087832041555242,0.3549240461223025 -ICU,92,0.22070842167725047,0.06578358667632574,0.10419476654227489,0.33313378997283916 -ICU,93,0.206968001139338,0.06066099927603088,0.0993833732199374,0.31077526580830395 -ICU,94,0.19437412083179162,0.055975886018670706,0.09496629157149848,0.29030002568893104 -ICU,95,0.1835282993863489,0.05195028704359591,0.09115611632650283,0.27268169127682657 -ICU,96,0.17393568653336444,0.048397720947271614,0.08778155836033638,0.2571337670699489 -ICU,97,0.16536106707812628,0.04522928270792874,0.0847415157518348,0.24328999113453553 -ICU,98,0.15780135630659056,0.04244241045619333,0.08203460930579379,0.23109248241505237 -ICU,99,0.1496122467177502,0.03943025492897487,0.0791002864499026,0.21788428809810245 -ICU,100,0.1443108481374491,0.03748701583500701,0.07719630597717707,0.20934230944404836 -ICU,101,0.1339969611975639,0.03371514573123381,0.07349365560880153,0.19272101584469187 -ICU,102,0.12658113221824718,0.031019241869526055,0.07082318749690954,0.1807836918228434 -ICU,103,0.11308143733539941,0.02615742701798706,0.06435091615096654,0.15908012127403895 -ICU,104,0.0937666580317278,0.019427244438138615,0.05764752375996203,0.1282153229007603 -ICU,105,0.062468520502315404,0.010324282153352576,0.043172180417829005,0.08019481966980326 -Non-hospitalised (no AD),0,0.06029255359492132,0.0031930620711356763,0.05334779675495315,0.0666896801150587 -Non-hospitalised (no AD),1,0.06029176427928104,0.0031930620711356755,0.053347007439312887,0.06668889079941842 -Non-hospitalised (no AD),2,0.06029055916491195,0.003193062071135676,0.05334580232494379,0.06668768568504933 -Non-hospitalised (no AD),3,0.06028905939139321,0.0031930620711356737,0.053344302551425034,0.06668618591153058 -Non-hospitalised (no AD),4,0.06028731676040839,0.003193062071135674,0.05334255992044022,0.06668444328054576 -Non-hospitalised (no AD),5,0.06028536263832295,0.003193062071135676,0.0533406057983548,0.06668248915846033 -Non-hospitalised (no AD),6,0.06028321870846666,0.0031930620711356733,0.05333846186849849,0.06668034522860404 -Non-hospitalised (no AD),7,0.06028090113002562,0.003193062071135676,0.053336144290057445,0.066678027650163 -Non-hospitalised (no AD),8,0.06027842255151544,0.0031930620711356768,0.05333366571154727,0.06667554907165282 -Non-hospitalised (no AD),9,0.06027579322412005,0.003193062071135675,0.05333103638415189,0.06667291974425744 -Non-hospitalised (no AD),10,0.060273021675130954,0.003193062071135677,0.053328264835162786,0.06667014819526833 -Non-hospitalised (no AD),11,0.06027011514278785,0.0031930620711356737,0.053325358302819696,0.06666724166292522 -Non-hospitalised (no AD),12,0.06026707987141093,0.0031930620711356785,0.05332232303144276,0.06666420639154831 -Non-hospitalised (no AD),13,0.0602639213197678,0.0031930620711356763,0.05331916447979963,0.06666104783990519 -Non-hospitalised (no AD),14,0.060260644312967605,0.0031930620711356763,0.05331588747299945,0.06665777083310499 -Non-hospitalised (no AD),15,0.060257253156165626,0.003193062071135676,0.05331249631619746,0.066654379676303 -Non-hospitalised (no AD),16,0.060253751721605416,0.0031930620711356755,0.053308994881637255,0.06665087824174279 -Non-hospitalised (no AD),17,0.0602501435165371,0.0031930620711356763,0.053305386676568936,0.06664727003667446 -Non-hospitalised (no AD),18,0.060246431737097705,0.0031930620711356763,0.05330167489712953,0.06664355825723507 -Non-hospitalised (no AD),19,0.060242619311677154,0.0031930620711356755,0.05329786247170899,0.06663974583181453 -Non-hospitalised (no AD),20,0.060238708936269834,0.003193062071135676,0.05329395209630166,0.06663583545640721 -Non-hospitalised (no AD),21,0.060234703103620474,0.003193062071135675,0.05328994626365231,0.06663182962375785 -Non-hospitalised (no AD),22,0.06023060412749874,0.003193062071135676,0.05328584728753057,0.06662773064763612 -Non-hospitalised (no AD),23,0.060226414163101094,0.0031930620711356763,0.05328165732313292,0.06662354068323847 -Non-hospitalised (no AD),24,0.06022213522434054,0.0031930620711356755,0.053277378384372374,0.06661926174447792 -Non-hospitalised (no AD),25,0.06021776919860827,0.003193062071135676,0.053273012358640105,0.06661489571874565 -Non-hospitalised (no AD),26,0.0602133178594639,0.003193062071135674,0.05326856101949574,0.06661044437960126 -Non-hospitalised (no AD),27,0.060208782877613415,0.003193062071135676,0.05326402603764525,0.0666059093977508 -Non-hospitalised (no AD),28,0.06020416583046093,0.0031930620711356737,0.05325940899049278,0.06660129235059832 -Non-hospitalised (no AD),29,0.06019946821046347,0.0031930620711356776,0.053254711370495304,0.06659659473060084 -Non-hospitalised (no AD),30,0.06019469143247587,0.003193062071135677,0.0532499345925077,0.06659181795261325 -Non-hospitalised (no AD),31,0.06018983684023626,0.0031930620711356746,0.05324508000026809,0.06658696336037363 -Non-hospitalised (no AD),32,0.06018490571211828,0.003193062071135677,0.05324014887215012,0.06658203223225566 -Non-hospitalised (no AD),33,0.06017989926625244,0.0031930620711356746,0.05323514242628427,0.06657702578638983 -Non-hospitalised (no AD),34,0.06017481866510344,0.003193062071135673,0.05323006182513529,0.06657194518524083 -Non-hospitalised (no AD),35,0.06016966501957544,0.0031930620711356746,0.05322490817960727,0.0665667915397128 -Non-hospitalised (no AD),36,0.06016443939270538,0.003193062071135674,0.05321968255273722,0.06656156591284276 -Non-hospitalised (no AD),37,0.060159142802997286,0.0031930620711356724,0.053214385963029125,0.06655626932313466 -Non-hospitalised (no AD),38,0.0601537762274399,0.0031930620711356763,0.05320901938747172,0.06655090274757727 -Non-hospitalised (no AD),39,0.060148340604246106,0.003193062071135677,0.053203583764277945,0.0665454671243835 -Non-hospitalised (no AD),40,0.06014283683534594,0.003193062071135675,0.053198079995377776,0.06653996335548332 -Non-hospitalised (no AD),41,0.06013726578866109,0.003193062071135674,0.05319250894869293,0.06653439230879847 -Non-hospitalised (no AD),42,0.060131628300184696,0.003193062071135676,0.05318687146021653,0.06652875482032207 -Non-hospitalised (no AD),43,0.060125925175887544,0.0031930620711356733,0.0531811683359194,0.06652305169602492 -Non-hospitalised (no AD),44,0.06012015719346896,0.003193062071135676,0.05317540035350079,0.06651728371360634 -Non-hospitalised (no AD),45,0.060114325103967865,0.0031930620711356785,0.0531695682639997,0.06651145162410524 -Non-hospitalised (no AD),46,0.06010842963324836,0.003193062071135678,0.0531636727932802,0.06650555615338576 -Non-hospitalised (no AD),47,0.06010247148337229,0.003193062071135677,0.053157714643404116,0.06649959800350967 -Non-hospitalised (no AD),48,0.06009645133386903,0.003193062071135674,0.053151694493900864,0.0664935778540064 -Non-hospitalised (no AD),49,0.060090369842912716,0.003193062071135677,0.053145613002944556,0.0664874963630501 -Non-hospitalised (no AD),50,0.06008422764841499,0.0031930620711356737,0.053139470808446825,0.06648135416855237 -Non-hospitalised (no AD),51,0.06007802536904155,0.003193062071135677,0.05313326852907337,0.06647515188917894 -Non-hospitalised (no AD),52,0.06007176360515836,0.0031930620711356763,0.05312700676519019,0.06646889012529575 -Non-hospitalised (no AD),53,0.06006544293971397,0.0031930620711356737,0.05312068609974581,0.06646256945985134 -Non-hospitalised (no AD),54,0.06005906393906416,0.003193062071135675,0.053114307099095995,0.06645619045920155 -Non-hospitalised (no AD),55,0.060052627153741954,0.003193062071135676,0.053107870313773786,0.06644975367387934 -Non-hospitalised (no AD),56,0.06004613311917954,0.003193062071135676,0.05310137627921138,0.06644325963931692 -Non-hospitalised (no AD),57,0.06003958235638426,0.003193062071135676,0.05309482551641609,0.06643670887652164 -Non-hospitalised (no AD),58,0.06003297537257349,0.0031930620711356746,0.053088218532605334,0.06643010189271088 -Non-hospitalised (no AD),59,0.06002631266177076,0.003193062071135674,0.05308155582180259,0.06642343918190813 -Non-hospitalised (no AD),60,0.06001959470536669,0.003193062071135675,0.05307483786539854,0.06641672122550409 -Non-hospitalised (no AD),61,0.06001282197264703,0.003193062071135674,0.053068065132678845,0.06640994849278442 -Non-hospitalised (no AD),62,0.060005994921290225,0.003193062071135673,0.05306123808132205,0.06640312144142758 -Non-hospitalised (no AD),63,0.05999911399783718,0.003193062071135676,0.05305435715786902,0.06639624051797458 -Non-hospitalised (no AD),64,0.05999217963813454,0.0031930620711356768,0.05304742279816637,0.06638930615827192 -Non-hospitalised (no AD),65,0.05998519226775367,0.0031930620711356746,0.0530404354277855,0.06638231878789104 -Non-hospitalised (no AD),66,0.05997815230238733,0.003193062071135678,0.053033395462419156,0.06637527882252471 -Non-hospitalised (no AD),67,0.05997106014822497,0.0031930620711356776,0.05302630330825679,0.06636818666836235 -Non-hospitalised (no AD),68,0.059963916202308475,0.003193062071135676,0.05301915936234031,0.06636104272244586 -Non-hospitalised (no AD),69,0.05995672085286967,0.003193062071135676,0.05301196401290151,0.06635384737300705 -Non-hospitalised (no AD),70,0.05994947447965047,0.0031930620711356724,0.05300471763968231,0.06634660099978784 -Non-hospitalised (no AD),71,0.05994217745420721,0.0031930620711356746,0.05299742061423904,0.06633930397434458 -Non-hospitalised (no AD),72,0.05993483014019958,0.0031930620711356746,0.052990073300231415,0.06633195666033695 -Non-hospitalised (no AD),73,0.05992743289366595,0.003193062071135676,0.05298267605369779,0.06632455941380332 -Non-hospitalised (no AD),74,0.05991998606328523,0.0031930620711356755,0.05297522922331707,0.0663171125834226 -Non-hospitalised (no AD),75,0.05991248999062619,0.003193062071135675,0.05296773315065802,0.06630961651076357 -Non-hospitalised (no AD),76,0.059904945010385256,0.003193062071135676,0.05296018817041709,0.06630207153052263 -Non-hospitalised (no AD),77,0.059897351450613485,0.0031930620711356768,0.052952594610645325,0.06629447797075086 -Non-hospitalised (no AD),78,0.05988970963293282,0.00319306207113567,0.05294495279296467,0.06628683615307018 -Non-hospitalised (no AD),79,0.05988201987274277,0.0031930620711356364,0.052937263032774684,0.06627914639288006 -Non-hospitalised (no AD),80,0.05987428247941585,0.003193062071135402,0.05292952563944828,0.06627140899955268 -Non-hospitalised (no AD),81,0.05986649775647407,0.0031930620711337915,0.05292174091650999,0.06626362427660766 -Non-hospitalised (no AD),82,0.059858666001684664,0.003193062071123015,0.05291390916174404,0.06625579252179668 -Non-hospitalised (no AD),83,0.059850787506742026,0.003193062071056676,0.052906030666945686,0.06624791402672113 -Non-hospitalised (no AD),84,0.05984286255495859,0.0031930620706910476,0.05289810571595747,0.06623998907420517 -Non-hospitalised (no AD),85,0.05983489140801366,0.00319306206873612,0.052890134573264413,0.06623201792334366 -Non-hospitalised (no AD),86,0.059826874253511464,0.0031930620595796884,0.05288211743867702,0.06622400075049706 -Non-hospitalised (no AD),87,0.05981881099352319,0.003193062020262887,0.0528740542642009,0.06621593741173969 -Non-hospitalised (no AD),88,0.05981070064253304,0.003193061873988036,0.052865944231351526,0.06620782676769582 -Non-hospitalised (no AD),89,0.05980253949778719,0.0031930613802687415,0.052857784160421466,0.06619966463381016 -Non-hospitalised (no AD),90,0.05979431488017847,0.003193059762162378,0.05284956306211648,0.06619143677441319 -Non-hospitalised (no AD),91,0.059786001628082425,0.003193055512139497,0.05284125905361633,0.06618311500762701 -Non-hospitalised (no AD),92,0.05977753903779032,0.003193045038102848,0.052832819243851525,0.06617463143317108 -Non-hospitalised (no AD),93,0.059768731933064034,0.003193016891267665,0.0528240733571416,0.0661657679377885 -Non-hospitalised (no AD),94,0.05975925335043598,0.0031929521396936397,0.052814735606081034,0.066156159628897 -Non-hospitalised (no AD),95,0.05974868116597643,0.00319282661176662,0.05280443643884145,0.06614533595605013 -Non-hospitalised (no AD),96,0.05973633737288206,0.0031926016303583573,0.052792581969518144,0.0661325414249177 -Non-hospitalised (no AD),97,0.05972131022845656,0.0031922255124567146,0.05277837286348711,0.06611676074869428 -Non-hospitalised (no AD),98,0.05970271481623804,0.0031916485895821223,0.05276103223084701,0.0660970095028155 -Non-hospitalised (no AD),99,0.05967525246705556,0.0031905702904732086,0.05273591513050257,0.06606738683990512 -Non-hospitalised (no AD),100,0.059647360324840124,0.0031894726892766232,0.05271041021823998,0.06603729571327699 -Non-hospitalised (no AD),101,0.059573037673724835,0.003185756547273082,0.05264416999772655,0.06595552797339303 -Non-hospitalised (no AD),102,0.05947847975289102,0.0031809211356009976,0.052560128865334566,0.06585128256777059 -Non-hospitalised (no AD),103,0.05914189828026596,0.003162609149460371,0.052263375084176306,0.06547801402500196 -Non-hospitalised (no AD),104,0.057688624947724386,0.0030829074112927795,0.050983449209017505,0.06386506258675051 -Non-hospitalised (no AD),105,0.04757983852739725,0.0025353059430420445,0.04206566971479698,0.05265918635201617 diff --git a/data/QALY_model/interim/long_COVID/average_QALY_losses_per_age_SMR100.csv b/data/QALY_model/interim/long_COVID/average_QALY_losses_per_age_SMR100.csv new file mode 100644 index 000000000..a16c772c1 --- /dev/null +++ b/data/QALY_model/interim/long_COVID/average_QALY_losses_per_age_SMR100.csv @@ -0,0 +1,425 @@ +hospitalisation,age,mean,sd,lower,upper +Non-hospitalised,0,,,, +Non-hospitalised,1,,,, +Non-hospitalised,2,,,, +Non-hospitalised,3,,,, +Non-hospitalised,4,,,, +Non-hospitalised,5,,,, +Non-hospitalised,6,,,, +Non-hospitalised,7,,,, +Non-hospitalised,8,,,, +Non-hospitalised,9,,,, +Non-hospitalised,10,,,, +Non-hospitalised,11,,,, +Non-hospitalised,12,,,, +Non-hospitalised,13,,,, +Non-hospitalised,14,,,, +Non-hospitalised,15,,,, +Non-hospitalised,16,,,, +Non-hospitalised,17,,,, +Non-hospitalised,18,,,, +Non-hospitalised,19,,,, +Non-hospitalised,20,,,, +Non-hospitalised,21,,,, +Non-hospitalised,22,,,, +Non-hospitalised,23,,,, +Non-hospitalised,24,,,, +Non-hospitalised,25,,,, 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+Non-hospitalised,99,0.05893216363182444,0.006917901396237798,0.047480459961681466,0.0735471354749697 +Non-hospitalised,100,0.05841113554170002,0.006721574235632432,0.047217699380334446,0.07250741796315739 +Non-hospitalised,101,0.056792687648659544,0.0061184691960879025,0.0463669201575408,0.0693903268888641 +Non-hospitalised,102,0.0561004570630279,0.0058678217266162356,0.045997641783945116,0.06814937572294409 +Non-hospitalised,103,0.0541670890468859,0.005193189829185163,0.04493278572752034,0.06474419863070667 +Non-hospitalised,104,0.05076425143864377,0.004161015296416293,0.04321347389191943,0.0593286141058432 +Non-hospitalised,105,0.04217416684953291,0.002648531198275986,0.03715099723197867,0.04768969718325404 +Hospitalised (no IC),0,2.060550970737883,0.7888757196302463,0.6683595904619504,3.7080219762562714 +Hospitalised (no IC),1,2.0363948202710738,0.7799912186269522,0.6614378642869501,3.6678680157507286 +Hospitalised (no IC),2,2.0066300146995264,0.7685883415828335,0.6527012154780786,3.615680579885052 +Hospitalised (no IC),3,1.9767622645757577,0.7571249807566349,0.6439242124415689,3.5631826091994325 +Hospitalised (no IC),4,1.9470639385572024,0.7457203382515437,0.6351935804767438,3.5109397957901076 +Hospitalised (no IC),5,1.917411121602378,0.7343165027963666,0.6264682878053354,3.4586737659404925 +Hospitalised (no IC),6,1.887996684635413,0.722998220164478,0.6178098753534833,3.406402183796311 +Hospitalised (no IC),7,1.8587240532969935,0.7117206190903365,0.6091864940758075,3.3536834296939855 +Hospitalised (no IC),8,1.8296497929397404,0.7005078452200524,0.6006158978208778,3.301286014019721 +Hospitalised (no IC),9,1.8008149053594045,0.6893772690400981,0.5921109003751648,3.2492885153371676 +Hospitalised (no IC),10,1.7721714304894183,0.6783064877394303,0.5836556597464475,3.1975933984151923 +Hospitalised (no IC),11,1.7437250070515968,0.6672973290792279,0.575251723111404,3.1462100509968733 +Hospitalised (no IC),12,1.715578664625572,0.6563954710136762,0.5669321305400534,3.0953414646270807 +Hospitalised (no IC),13,1.6875947786429562,0.6455386920630447,0.558652297886863,3.044713512318828 +Hospitalised (no IC),14,1.6599703629537774,0.6348150427980326,0.5504756696954926,2.994716104684617 +Hospitalised (no IC),15,1.6324791639201583,0.6241227966077958,0.5423291962508108,2.944900195458608 +Hospitalised (no IC),16,1.6053729570970605,0.6135746756221053,0.5342940141263027,2.895764453980293 +Hospitalised (no IC),17,1.5784428586749673,0.6030769866476617,0.52630279556631,2.846895047878617 +Hospitalised (no IC),18,1.551804549619825,0.5926815610594294,0.5183928468174056,2.798521266412659 +Hospitalised (no IC),19,1.5255915294755835,0.5824481301164379,0.5106071589886956,2.7509073212490027 +Hospitalised (no IC),20,1.4994641704860123,0.5722249321031965,0.5028365364401912,2.703382142405479 +Hospitalised (no IC),21,1.4735661643391043,0.5620764963394806,0.49512736355927656,2.6562308359768565 +Hospitalised (no IC),22,1.448101912946431,0.5520942628396454,0.4875454270861814,2.609950794307127 +Hospitalised (no IC),23,1.4227188005764955,0.5421212374137793,0.4799776330877759,2.563757793983562 +Hospitalised (no IC),24,1.397558374419206,0.5322210135811685,0.4724696665901301,2.5179194820521773 +Hospitalised (no IC),25,1.3726244868686008,0.5223957696210195,0.4650229877975357,2.472445291860925 +Hospitalised (no IC),26,1.3478355459022227,0.5126098077876864,0.4576117254538307,2.4271746232736193 +Hospitalised (no IC),27,1.3234059815327435,0.5029588358051352,0.4503047672260066,2.3825364980368464 +Hospitalised (no IC),28,1.299103893583911,0.4933405834805126,0.44302818782783226,2.3380714043640185 +Hospitalised (no IC),29,1.275033830631171,0.48380204312932285,0.4357333863968854,2.293989660744019 +Hospitalised (no IC),30,1.2511791637152294,0.4743365105811507,0.42845019319101235,2.250260529823485 +Hospitalised (no IC),31,1.2275947432541539,0.4649688127898837,0.42124949472075984,2.2069949299607927 +Hospitalised (no IC),32,1.2041146482911393,0.45562663091777283,0.414080687693152,2.163867032340474 +Hospitalised (no IC),33,1.1807931940121141,0.4463347768720132,0.4069603316604516,2.1209874237538986 +Hospitalised (no IC),34,1.1576966011112484,0.43712310824617834,0.3999086180474428,2.0784895593360924 +Hospitalised (no IC),35,1.1347096628384705,0.4279420391244117,0.3928904071591954,2.036149316271681 +Hospitalised (no IC),36,1.1119348212749152,0.41883724043990694,0.38593693735933526,1.9941713465465947 +Hospitalised (no IC),37,1.0892851785055717,0.40977169332640256,0.37902170150031494,1.9523878743519205 +Hospitalised (no IC),38,1.0668651724575868,0.4007916950487877,0.3721765480293014,1.9110066270134398 +Hospitalised (no IC),39,1.0445755054844943,0.39185497119085927,0.3653711871702948,1.8698359602586208 +Hospitalised (no IC),40,1.0225495907053996,0.38302008303668533,0.3586463065018931,1.8291392696018636 +Hospitalised (no IC),41,1.000649440502176,0.37422816784898505,0.3519598146954451,1.7886498365728896 +Hospitalised (no IC),42,0.9787965784726628,0.36544648480122605,0.3452877696023148,1.748218424552922 +Hospitalised (no IC),43,0.9572316691529349,0.35677934464091293,0.3387035747815571,1.7083157233604436 +Hospitalised (no IC),44,0.9356839618999959,0.3481114507425498,0.3321246396840985,1.6684190445568392 +Hospitalised (no IC),45,0.9143133324694183,0.33951221338854837,0.325599726465226,1.628841455949311 +Hospitalised (no IC),46,0.8932402363993908,0.33103355768071074,0.3191655762523056,1.5898176049593817 +Hospitalised (no IC),47,0.8721644862294633,0.32254848379809625,0.3127306142721532,1.5507707375412783 +Hospitalised (no IC),48,0.8512754837125669,0.3141383488625056,0.3063526128716732,1.5120688471873907 +Hospitalised (no IC),49,0.8304333803905739,0.30574475886624514,0.2999889059241259,1.473445811604065 +Hospitalised (no IC),50,0.8098643916743308,0.2974639125008499,0.29370850020255573,1.4353379302643092 +Hospitalised (no IC),51,0.789329141098889,0.2891956140387329,0.2874383658496502,1.3972888723739183 +Hospitalised (no IC),52,0.7690636005480476,0.2810396227556537,0.28125048908228667,1.3597518069083083 +Hospitalised (no IC),53,0.7488771478207469,0.2729165671787418,0.27508671187206407,1.3223647416360154 +Hospitalised (no IC),54,0.7288794443674487,0.26487288963003575,0.2689804874989621,1.285338564936116 +Hospitalised (no IC),55,0.7090578060306445,0.25690372093547004,0.2629279439970828,1.2486505887240185 +Hospitalised (no IC),56,0.6892746424888133,0.24895247976012233,0.2568870992042889,1.2120419041355088 +Hospitalised (no IC),57,0.669621646513413,0.24105786151344777,0.25088592565535417,1.17568839947958 +Hospitalised (no IC),58,0.6501163317047317,0.23322757092691113,0.24492976460327445,1.1396247413595229 +Hospitalised (no IC),59,0.6308143176892278,0.22548487110612575,0.23903558507297085,1.1039569317606805 +Hospitalised (no IC),60,0.611485883624957,0.2177357743699606,0.23304443138255534,1.0682542939821327 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IC),70,0.43205292098132664,0.14619608775028822,0.17653053966077273,0.7381421768707311 +Hospitalised (no IC),71,0.4151868176493833,0.13951294849575946,0.1711266537008419,0.7072491054099141 +Hospitalised (no IC),72,0.39835329890232346,0.13285053219197604,0.16571037181028667,0.6764407843963799 +Hospitalised (no IC),73,0.38191411342017706,0.12635336717717063,0.16024655973448065,0.6463834179770777 +Hospitalised (no IC),74,0.36565454757621274,0.1199356980242615,0.15482588917130707,0.6166810579088422 +Hospitalised (no IC),75,0.3498027773163508,0.11368813616858364,0.14973148832193164,0.5877518328130839 +Hospitalised (no IC),76,0.3340182386601056,0.10747549069598747,0.14490243656055263,0.5589704493095778 +Hospitalised (no IC),77,0.3180029461803833,0.1011805551231043,0.14000069351300753,0.5297929316074147 +Hospitalised (no IC),78,0.30298137479174536,0.09528709164041528,0.13540014573446865,0.5024571512684358 +Hospitalised (no IC),79,0.28755736798598447,0.0892443731843655,0.13067445669509287,0.47441179611162076 +Hospitalised (no IC),80,0.27282035243880326,0.08348167510154365,0.125844390671124,0.4476440350581566 +Hospitalised (no IC),81,0.2585733811533326,0.07792105031463101,0.1209786167532723,0.421791848871391 +Hospitalised (no IC),82,0.24438100083920958,0.07239222228660891,0.11611940899566298,0.39606201818275544 +Hospitalised (no IC),83,0.23073703034311946,0.06708866348390205,0.11139342298390445,0.3713506691116126 +Hospitalised (no IC),84,0.21792322150520188,0.06211969071444573,0.1069185950796418,0.34816551376265276 +Hospitalised (no IC),85,0.2053264552057001,0.057246933705098306,0.1025085000244945,0.3253950828365652 +Hospitalised (no IC),86,0.19365353462160778,0.05274461484152754,0.09848198868833823,0.30435626767023455 +Hospitalised (no IC),87,0.18266613967090842,0.04851995829939202,0.09549991035389635,0.2850679085411586 +Hospitalised (no IC),88,0.17274289023299091,0.044717952153326794,0.09272031190004255,0.26777587283928833 +Hospitalised (no IC),89,0.16362982039231586,0.041239735497187756,0.09001613480213659,0.25191634840927724 +Hospitalised (no IC),90,0.15479149656729563,0.03788087574375309,0.08814644178588242,0.2365693917882648 +Hospitalised (no IC),91,0.1473728083565635,0.03507601192806938,0.08573085957313575,0.22370403636039893 +Hospitalised (no IC),92,0.14069995245735223,0.03256666807000206,0.08291113301529572,0.2119696812968471 +Hospitalised (no IC),93,0.13366081178898603,0.029936002197673287,0.08090523762304913,0.1990284689556939 +Hospitalised (no IC),94,0.12725829629858107,0.027562963860101538,0.07859788753181257,0.18729465358390862 +Hospitalised (no IC),95,0.1219077102207862,0.025598894383694813,0.07639351227874588,0.17727217936153702 +Hospitalised (no IC),96,0.11729776582159515,0.023924613747140715,0.07448855663963723,0.16859330845804624 +Hospitalised (no IC),97,0.11330456853718457,0.022491443853305388,0.07289939831098828,0.1612881694906993 +Hospitalised (no IC),98,0.1099988045428584,0.021320261534055585,0.0717728375345348,0.15543668204437266 +Hospitalised (no IC),99,0.10630053325954805,0.02002921503266152,0.0713475752385462,0.14852536501773733 +Hospitalised (no IC),100,0.10483647136874269,0.019527028120279524,0.07089971572898067,0.14594823614286248 +Hospitalised (no IC),101,0.10026883155297457,0.01798384349840153,0.06858688552190723,0.1381692591299623 +Hospitalised (no IC),102,0.09832344937394583,0.017345152340223734,0.06763556008471919,0.1352190706002572 +Hospitalised (no IC),103,0.09289679949439703,0.015625968544237506,0.0652563342906566,0.12612494947192782 +Hospitalised (no IC),104,0.08358195426944316,0.01298138279387945,0.06166624145534747,0.11183932523663703 +Hospitalised (no IC),105,0.06348426539360642,0.00879683576174061,0.04815228817165056,0.0814516592376916 +Hospitalised (IC),0,3.178450340383496,1.0623170074535604,1.3140975497574938,5.430456992554764 +Hospitalised (IC),1,3.140496962398689,1.0505792649017696,1.298580852651232,5.367496468356843 +Hospitalised (IC),2,3.093835175490928,1.03533720984766,1.2796523814220357,5.288435482108783 +Hospitalised (IC),3,3.0470171615833,1.020006165181638,1.260667594641326,5.209030263626919 +Hospitalised (IC),4,3.0004665128356662,1.0047510036712164,1.2417934932155936,5.130052433213498 +Hospitalised (IC),5,2.953991281067552,0.9894904546821763,1.2229555822550293,5.051139385055839 +Hospitalised (IC),6,2.9078913634876313,0.9743418357590797,1.2042719913114273,4.9728385265597135 +Hospitalised (IC),7,2.8620171018559604,0.9592422631145874,1.185684537832481,4.894868228560734 +Hospitalised (IC),8,2.816456595187438,0.9442249432286011,1.1672281418607244,4.817386895868006 +Hospitalised (IC),9,2.7712737298417123,0.9293137231377602,1.1489281668300257,4.740508949441524 +Hospitalised (IC),10,2.7263941960965883,0.9144771840947087,1.1307557420825851,4.664094345371307 +Hospitalised (IC),11,2.681826885054892,0.8997176644258332,1.11271455685302,4.588157252815025 +Hospitalised (IC),12,2.6377319179162613,0.8850985246896663,1.09486755911838,4.512993391405647 +Hospitalised (IC),13,2.593895628036395,0.8705331134856282,1.0771310862924195,4.438216581184943 +Hospitalised (IC),14,2.5506240705080776,0.8561437694425108,1.0596252599428762,4.364378267826749 +Hospitalised (IC),15,2.507565857968617,0.8417890014375862,1.042212310292444,4.290829378563812 +Hospitalised (IC),16,2.465112088511329,0.8276254745651972,1.025045693906665,4.218291042717379 +Hospitalised (IC),17,2.422938294695457,0.8135229506946552,1.007998112854624,4.146164846742787 +Hospitalised (IC),18,2.381224156664237,0.7995534855159903,0.9911400502226164,4.074782310850455 +Hospitalised (IC),19,2.340177062002841,0.7858000768891152,0.9745529018532879,4.004525577701261 +Hospitalised (IC),20,2.2992693180804413,0.7720519632788023,0.9580294384205942,3.9344236799763537 +Hospitalised (IC),21,2.2587240904997077,0.7583988896411518,0.9416571674758797,3.864888745413267 +Hospitalised (IC),22,2.218858930879599,0.7449678917028844,0.9255607475866986,3.7965056166428996 +Hospitalised (IC),23,2.179125828465366,0.7315411406260464,0.9095247690182702,3.7282682132507987 +Hospitalised (IC),24,2.139744621968403,0.7182070785168433,0.8936354396074567,3.6605824630861927 +Hospitalised (IC),25,2.100721185805665,0.7049688905997434,0.8778949072994459,3.593460978211861 +Hospitalised (IC),26,2.061928566454241,0.6917772635862789,0.8622530553262622,3.526673114798387 +Hospitalised (IC),27,2.02369995825727,0.6787650742115274,0.8468407740756976,3.460831493191233 +Hospitalised (IC),28,1.9856747327824613,0.6657907546783706,0.8315159825651262,3.3952777362074706 +Hospitalised (IC),29,1.9480152703745148,0.6529196556024611,0.8163423635735789,3.3303115997799377 +Hospitalised (IC),30,1.910695568813772,0.6401427087129619,0.8013094677364597,3.2658879337807165 +Hospitalised (IC),31,1.8738007821269194,0.6274944945786368,0.7864506375713674,3.2021645390991056 +Hospitalised (IC),32,1.837072697738092,0.614875189225124,0.7716638689151254,3.138673100085246 +Hospitalised (IC),33,1.800595590762051,0.6023194232245622,0.756982090344825,3.075570577274101 +Hospitalised (IC),34,1.7644722968182258,0.5898687420333392,0.7424456099704978,3.013047058529257 +Hospitalised (IC),35,1.728523391189749,0.5774549075757732,0.7279833518850591,2.9507793406642793 +Hospitalised (IC),36,1.6929080742215767,0.5651412992030072,0.7136578843480955,2.8890598092664455 +Hospitalised (IC),37,1.6574909280748922,0.5528770991570338,0.6994154459227953,2.8276458669248665 +Hospitalised (IC),38,1.6224343131722392,0.5407264682185543,0.685319931450076,2.766834746376942 +Hospitalised (IC),39,1.587583484026745,0.5286313810999885,0.6713098996137408,2.706349300490202 +Hospitalised (IC),40,1.5531459721294658,0.516672805049435,0.6574672038718309,2.6465673972563875 +Hospitalised (IC),41,1.518906763581826,0.5047699056029838,0.6437065106414784,2.5871035282680546 +Hospitalised (IC),42,1.4847434184150972,0.4928779642889045,0.629978999689619,2.52774073046308 +Hospitalised (IC),43,1.4510305890137483,0.48114076896758284,0.6164328519513979,2.4691564965191093 +Hospitalised (IC),44,1.417346347618302,0.4694000521782775,0.6029005545543752,2.410595012147343 +Hospitalised (IC),45,1.3839395546746855,0.4577515275106836,0.5894805001996748,2.352506699793231 +Hospitalised (IC),46,1.350997788135381,0.4462666744703075,0.5762469659962149,2.2952297782196984 +Hospitalised (IC),47,1.3180530702887951,0.43477143414500374,0.5630139006142704,2.2379288323775093 +Hospitalised (IC),48,1.2854004065768512,0.4233777081270147,0.5498982092215218,2.181134775364892 +Hospitalised (IC),49,1.252821615305268,0.4120057158766751,0.53681291273776,2.124460806104398 +Hospitalised (IC),50,1.2206692477730154,0.40078745356212503,0.5238980189104191,2.068538030681997 +Hospitalised (IC),51,1.1885698980994226,0.3895859495794265,0.511004742941351,2.012703610402248 +Hospitalised (IC),52,1.1568914475116003,0.37853788975816866,0.49827936079569163,1.957614056106107 +Hospitalised (IC),53,1.1253364529658516,0.3675349042656585,0.4856032261563164,1.9027428318073212 +Hospitalised (IC),54,1.0940758583742176,0.3566406447813631,0.47304428247966274,1.848395303290754 +Hospitalised (IC),55,1.0630897817513585,0.34584858687685427,0.46059446985893227,1.7945377373563083 +Hospitalised (IC),56,1.0321633778120387,0.3350817037672996,0.4481678695737955,1.7407970522058631 +Hospitalised (IC),57,1.0014396087291353,0.3243929753526299,0.4358213446186215,1.687423749421175 +Hospitalised (IC),58,0.9709457118803051,0.31379303519049856,0.4235656295893165,1.6344668753979474 +Hospitalised (IC),59,0.9407684502514716,0.3033136527300779,0.4114352981871076,1.582080352982992 +Hospitalised (IC),60,0.9105490161088274,0.29282703288644574,0.39928671199017823,1.5296349799776798 +Hospitalised (IC),61,0.8809611766832122,0.2825745060509121,0.3873893382836306,1.478315124692939 +Hospitalised (IC),62,0.8517733155140552,0.272473054138603,0.37565054593360203,1.4277136263018941 +Hospitalised (IC),63,0.82321155846687,0.26260260109439554,0.36416095711683677,1.378225915981521 +Hospitalised (IC),64,0.7949059992330235,0.25283185900695515,0.35277240953189226,1.3292042292688182 +Hospitalised (IC),65,0.7669361610729237,0.24318912524430705,0.34151673606956273,1.280788041150603 +Hospitalised (IC),66,0.7393196311127035,0.23368061316190716,0.33040098099958143,1.233008151742061 +Hospitalised (IC),67,0.7115559434847096,0.22413126105055114,0.31922423385659715,1.1849932170861937 +Hospitalised (IC),68,0.6845106071031025,0.214844302924399,0.30833385245128253,1.1382512399671412 +Hospitalised (IC),69,0.6567686814005423,0.20532650516172138,0.29716151564787585,1.09032202656409 +Hospitalised (IC),70,0.6299308373006038,0.1961358540254393,0.2863428776396084,1.0439888054427102 +Hospitalised (IC),71,0.6035453832757195,0.18711437964332836,0.2757009008899831,0.9984651833656782 +Hospitalised (IC),72,0.577209341210449,0.17812262650472813,0.26507591424977434,0.9530525235333872 +Hospitalised (IC),73,0.5514885040423124,0.169355867468065,0.2546956586893134,0.9087306624368511 +Hospitalised (IC),74,0.5260470823416233,0.16069796777904977,0.24442503506721774,0.8649175411910917 +Hospitalised (IC),75,0.5012420880167279,0.1522711079848149,0.23440798987445918,0.8222292898559429 +Hospitalised (IC),76,0.476540740238586,0.14389244098464096,0.22442984893021767,0.7797451895322494 +Hospitalised (IC),77,0.45147666732546443,0.13540355566145776,0.21404539178387194,0.7366625098748018 +Hospitalised (IC),78,0.4279661070294624,0.1274570939497992,0.20423866713390265,0.6962821724336845 +Hospitalised (IC),79,0.4038241276770303,0.11930935074987145,0.19415297869754974,0.6548407384220591 +Hospitalised (IC),80,0.3807558724525932,0.11153914623811369,0.18449644519953928,0.615271509006565 +Hospitalised (IC),81,0.3584532624449723,0.10404071870032378,0.17512762194306664,0.577041656114385 +Hospitalised (IC),82,0.33623466843088956,0.09658365415472273,0.16577266552722827,0.5389796928214013 +Hospitalised (IC),83,0.31487329910379763,0.08942825518727149,0.1567612434781212,0.5024109999405115 +Hospitalised (IC),84,0.29481054321984823,0.08272135046462945,0.14828143700872198,0.46808850488371634 +Hospitalised (IC),85,0.27508647867798053,0.07614018080958271,0.13993075000452534,0.43436819013912803 +Hospitalised (IC),86,0.25680814310524336,0.07005431544654477,0.13217829036933013,0.4031415583609756 +Hospitalised (IC),87,0.23960253994807792,0.06433765356055053,0.12486900717239502,0.3737646380224387 +Hospitalised (IC),88,0.22406294548199507,0.05918605314455494,0.11889575724762283,0.3472473790266164 +Hospitalised (IC),89,0.2097918531646645,0.05446552196626553,0.11391920066584302,0.3229069661893453 +Hospitalised (IC),90,0.19595081505170234,0.04989771799077956,0.10803987482357108,0.29931029448694807 +Hospitalised (IC),91,0.1843337448232302,0.04607421047952968,0.10298904775246374,0.27951499219775483 +Hospitalised (IC),92,0.17388575631911285,0.042644409768577855,0.0988827420745966,0.2617117649103643 +Hospitalised (IC),93,0.1628662186502877,0.03903681514329209,0.09455022645447252,0.24292257380643764 +Hospitalised (IC),94,0.15284848953061633,0.03576898848833136,0.09045584130992376,0.22614812726947917 +Hospitalised (IC),95,0.14448499343880086,0.03305187887385551,0.08630960918447507,0.21199627438760493 +Hospitalised (IC),96,0.13729040251162458,0.030724506692199567,0.083241358224625,0.19982841102490476 +Hospitalised (IC),97,0.13107254069655977,0.028722383519109176,0.08018611456142465,0.18931810746958325 +Hospitalised (IC),98,0.12594083461900138,0.027078241754561274,0.07743782826497345,0.18072539825871725 +Hospitalised (IC),99,0.12022346025521988,0.025256207251366757,0.07509774098897389,0.17141239987937967 +Hospitalised (IC),100,0.117972260603411,0.02454435582090534,0.07414414172231953,0.16779963403947112 +Hospitalised (IC),101,0.1109885998504508,0.022345421644977444,0.07142426864982918,0.156243505005749 +Hospitalised (IC),102,0.10804594024855034,0.021429685533756654,0.0701351362355526,0.15121509500937927 +Hospitalised (IC),103,0.09996451647776601,0.01894843674298452,0.06565638516597942,0.13784225519565388 +Hospitalised (IC),104,0.08679749694370059,0.015097732650710212,0.058989713517278074,0.11675783755954876 +Hospitalised (IC),105,0.06264459472043725,0.0092638766896983,0.044327411029311606,0.08061347171951193 +Non-hospitalised (no AD),0,0.060151384765614165,0.00296199242598553,0.0545442758177448,0.0658390978440777 +Non-hospitalised (no AD),1,0.060150551911818555,0.0029619924259855247,0.0545434429639492,0.06583826499028207 +Non-hospitalised (no AD),2,0.06014929602261962,0.0029619924259855265,0.054542187074750254,0.06583700910108314 +Non-hospitalised (no AD),3,0.06014774372921092,0.0029619924259855273,0.05454063478134155,0.06583545680767444 +Non-hospitalised (no AD),4,0.06014594860766808,0.002961992425985528,0.05453883965979872,0.06583366168613161 +Non-hospitalised (no AD),5,0.06014394292144243,0.0029619924259855265,0.05453683397357306,0.06583165599990594 +Non-hospitalised (no AD),6,0.06014174888653472,0.0029619924259855247,0.054534639938665364,0.06582946196499823 +Non-hospitalised (no AD),7,0.06013938300791945,0.0029619924259855247,0.05453227406005009,0.06582709608638297 +Non-hospitalised (no AD),8,0.060136858171694355,0.0029619924259855273,0.05452974922382499,0.06582457125015787 +Non-hospitalised (no AD),9,0.060134184798727404,0.0029619924259855273,0.05452707585085804,0.06582189787719092 +Non-hospitalised (no AD),10,0.06013137154086451,0.0029619924259855265,0.05452426259299515,0.06581908461932803 +Non-hospitalised (no AD),11,0.060128425729574345,0.0029619924259855273,0.054521316781704986,0.06581613880803786 +Non-hospitalised (no AD),12,0.06012535367991527,0.002961992425985526,0.05451824473204591,0.0658130667583788 +Non-hospitalised (no AD),13,0.06012216090480143,0.0029619924259855265,0.05451505195693206,0.06580987398326493 +Non-hospitalised (no AD),14,0.06011885227097529,0.0029619924259855273,0.05451174332310592,0.06580656534943881 +Non-hospitalised (no AD),15,0.060115432115613134,0.0029619924259855273,0.05450832316774377,0.06580314519407666 +Non-hospitalised (no AD),16,0.06011190433548072,0.002961992425985527,0.05450479538761135,0.06579961741394424 +Non-hospitalised (no AD),17,0.060108272456423674,0.002961992425985526,0.054501163508554315,0.06579598553488719 +Non-hospitalised (no AD),18,0.06010453968843771,0.002961992425985528,0.05449743074056834,0.06579225276690122 +Non-hospitalised (no AD),19,0.06010070896994915,0.002961992425985527,0.05449360002207979,0.06578842204841266 +Non-hospitalised (no AD),20,0.060096783003879384,0.0029619924259855273,0.05448967405601002,0.06578449608234291 +Non-hospitalised (no AD),21,0.060092764287352544,0.0029619924259855286,0.054485655339483186,0.06578047736581606 +Non-hospitalised (no AD),22,0.06008865513641798,0.002961992425985529,0.054481546188548606,0.06577636821488149 +Non-hospitalised (no AD),23,0.06008445770681233,0.002961992425985526,0.05447734875894296,0.06577217078527585 +Non-hospitalised (no AD),24,0.06008017401154179,0.002961992425985528,0.05447306506367242,0.06576788709000529 +Non-hospitalised (no AD),25,0.06007580593588244,0.002961992425985527,0.054468696988013064,0.06576351901434593 +Non-hospitalised (no AD),26,0.060071355250267515,0.002961992425985529,0.054464246302398156,0.06575906832873105 +Non-hospitalised (no AD),27,0.06006682362142825,0.0029619924259855265,0.05445971467355889,0.06575453669989177 +Non-hospitalised (no AD),28,0.06006221262208148,0.0029619924259855278,0.05445510367421212,0.06574992570054498 +Non-hospitalised (no AD),29,0.06005752373939834,0.0029619924259855273,0.05445041479152897,0.06574523681786186 +Non-hospitalised (no AD),30,0.060052758382444595,0.0029619924259855256,0.05444564943457523,0.06574047146090811 +Non-hospitalised (no AD),31,0.06004791788874731,0.002961992425985528,0.054440808940877945,0.06573563096721083 +Non-hospitalised (no AD),32,0.06004300353011553,0.0029619924259855286,0.05443589458224616,0.06573071660857906 +Non-hospitalised (no AD),33,0.0600380165178201,0.0029619924259855247,0.054430907569950726,0.06572572959628362 +Non-hospitalised (no AD),34,0.060032958007221075,0.002961992425985528,0.05442584905935171,0.06572067108568459 +Non-hospitalised (no AD),35,0.06002782910191531,0.0029619924259855278,0.05442072015404595,0.06571554218037882 +Non-hospitalised (no AD),36,0.060022630857467146,0.0029619924259855273,0.05441552190959777,0.06571034393593066 +Non-hospitalised (no AD),37,0.060017364284773556,0.0029619924259855265,0.05441025533690418,0.06570507736323708 +Non-hospitalised (no AD),38,0.06001203035310963,0.002961992425985528,0.05440492140524027,0.06569974343157314 +Non-hospitalised (no AD),39,0.06000662999289129,0.002961992425985525,0.05439952104502191,0.0656943430713548 +Non-hospitalised (no AD),40,0.060001164098188696,0.002961992425985528,0.05439405515031934,0.06568887717665221 +Non-hospitalised (no AD),41,0.05999563352901845,0.0029619924259855295,0.05438852458114909,0.06568334660748197 +Non-hospitalised (no AD),42,0.05999003911343858,0.002961992425985527,0.05438293016556921,0.0656777521919021 +Non-hospitalised (no AD),43,0.05998438164946832,0.0029619924259855265,0.05437727270159896,0.06567209472793184 +Non-hospitalised (no AD),44,0.05997866190685012,0.0029619924259855273,0.054371552958980746,0.06566637498531362 +Non-hospitalised (no AD),45,0.05997288062867103,0.0029619924259855265,0.05436577168080165,0.06566059370713455 +Non-hospitalised (no AD),46,0.05996703853285703,0.002961992425985528,0.05435992958498767,0.06565475161132053 +Non-hospitalised (no AD),47,0.05996113631355274,0.0029619924259855273,0.05435402736568336,0.06564884939201625 +Non-hospitalised (no AD),48,0.059955174642398135,0.0029619924259855265,0.05434806569452877,0.06564288772086166 +Non-hospitalised (no AD),49,0.05994915416971135,0.002961992425985527,0.05434204522184198,0.06563686724817487 +Non-hospitalised (no AD),50,0.05994307552558635,0.002961992425985529,0.054335966577716985,0.06563078860404985 +Non-hospitalised (no AD),51,0.05993693932091356,0.002961992425985527,0.0543298303730442,0.06562465239937709 +Non-hospitalised (no AD),52,0.059930746148329675,0.0029619924259855256,0.05432363720046031,0.0656184592267932 +Non-hospitalised (no AD),53,0.05992449658310352,0.0029619924259855286,0.05431738763523415,0.06561220966156704 +Non-hospitalised (no AD),54,0.05991819118396275,0.0029619924259855278,0.05431108223609338,0.06560590426242625 +Non-hospitalised (no AD),55,0.0599118304938666,0.0029619924259855273,0.05430472154599724,0.06559954357233012 +Non-hospitalised (no AD),56,0.059905415040729465,0.002961992425985528,0.0542983060928601,0.06559312811919298 +Non-hospitalised (no AD),57,0.05989894533809844,0.0029619924259855265,0.05429183639022908,0.06558665841656197 +Non-hospitalised (no AD),58,0.05989242188578975,0.0029619924259855247,0.054285312937920396,0.06558013496425327 +Non-hospitalised (no AD),59,0.05988584517048555,0.002961992425985527,0.05427873622261618,0.06557355824894907 +Non-hospitalised (no AD),60,0.0598792156662961,0.0029619924259855265,0.054272106718426735,0.06556692874475961 +Non-hospitalised (no AD),61,0.05987253383528822,0.0029619924259855273,0.05426542488741885,0.06556024691375173 +Non-hospitalised (no AD),62,0.05986580012798342,0.002961992425985526,0.05425869118011405,0.06555351320644694 +Non-hospitalised (no AD),63,0.05985901498382799,0.0029619924259855286,0.05425190603595862,0.0655467280622915 +Non-hospitalised (no AD),64,0.05985217883163641,0.002961992425985528,0.05424506988376704,0.06553989191009991 +Non-hospitalised (no AD),65,0.05984529209001051,0.002961992425985527,0.05423818314214115,0.06553300516847403 +Non-hospitalised (no AD),66,0.05983835516773617,0.0029619924259855286,0.0542312462198668,0.06552606824619968 +Non-hospitalised (no AD),67,0.05983136846415836,0.002961992425985527,0.054224259516289,0.06551908154262187 +Non-hospitalised (no AD),68,0.05982433236953692,0.002961992425985528,0.05421722342166756,0.06551204544800045 +Non-hospitalised (no AD),69,0.05981724726538352,0.002961992425985525,0.05421013831751414,0.06550496034384704 +Non-hospitalised (no AD),70,0.059810113524781744,0.0029619924259855256,0.05420300457691238,0.06549782660324525 +Non-hospitalised (no AD),71,0.05980293151269091,0.0029619924259855273,0.05419582256482154,0.06549064459115443 +Non-hospitalised (no AD),72,0.05979570158623467,0.002961992425985528,0.05418859263836531,0.06548341466469819 +Non-hospitalised (no AD),73,0.059788424094975916,0.002961992425985526,0.05418131514710654,0.06547613717343942 +Non-hospitalised (no AD),74,0.059781099381177843,0.002961992425985525,0.054173990433308485,0.06546881245964137 +Non-hospitalised (no AD),75,0.05977372778005308,0.0029619924259855187,0.054166618832183745,0.06546144085851657 +Non-hospitalised (no AD),76,0.05976630962000039,0.002961992425985462,0.05415920067213113,0.06545402269846379 +Non-hospitalised (no AD),77,0.05975884522282727,0.002961992425985072,0.05415173627495876,0.06544655830128991 +Non-hospitalised (no AD),78,0.05975133490394828,0.0029619924259827114,0.05414422595608425,0.06543904798240639 +Non-hospitalised (no AD),79,0.05974377897245998,0.002961992425967488,0.05413667002462476,0.06543149205088886 +Non-hospitalised (no AD),80,0.0597361777306891,0.0029619924258806355,0.0541290687830183,0.06542389080895121 +Non-hospitalised (no AD),81,0.05972853147101418,0.0029619924254175823,0.05412142252421995,0.0654162445483871 +Non-hospitalised (no AD),82,0.059720840457756816,0.002961992422965953,0.05411373151560356,0.06540855353042205 +Non-hospitalised (no AD),83,0.0597131048489438,0.002961992411117426,0.05410599592922004,0.06540081789885711 +Non-hospitalised (no AD),84,0.059705324406612144,0.0029619923602921083,0.05409821558310168,0.06539303735892905 +Non-hospitalised (no AD),85,0.05969749719255081,0.002961992145710998,0.05409038877524655,0.06538520973282218 +Non-hospitalised (no AD),86,0.059689616185669474,0.0029619913612522284,0.05408250925336083,0.06537732721959788 +Non-hospitalised (no AD),87,0.05968165825446967,0.0029619887167859167,0.0540745563281869,0.06536936421040887 +Non-hospitalised (no AD),88,0.0596735658581732,0.0029619810583400986,0.05406647842947648,0.06536125710811853 +Non-hospitalised (no AD),89,0.05966519940247553,0.0029619608178980844,0.054058150289327,0.0653528517860734 +Non-hospitalised (no AD),90,0.0596561801444678,0.0029619076289401306,0.05404923171904536,0.0653437303929187 +Non-hospitalised (no AD),91,0.059646086879081385,0.0029617991891914687,0.05403934373220042,0.06533342889804078 +Non-hospitalised (no AD),92,0.0596340299366675,0.0029615884192543762,0.05402768578135376,0.06532096722841786 +Non-hospitalised (no AD),93,0.059616979025086655,0.0029611152603646112,0.054011530568702226,0.0653030077419258 +Non-hospitalised (no AD),94,0.059591917699052054,0.0029602229583945393,0.05398815838755426,0.06527623298896254 +Non-hospitalised (no AD),95,0.05955707111500113,0.002958821550246423,0.05395596469623121,0.06523869537593316 +Non-hospitalised (no AD),96,0.059509588642845807,0.0029567648500134812,0.053912375597393807,0.06518726356187178 +Non-hospitalised (no AD),97,0.05944746717267621,0.002953951657707706,0.0538555795546667,0.06511974010939815 +Non-hospitalised (no AD),98,0.05937359886409686,0.0029505351834561797,0.05378817869792073,0.06503931137712826 +Non-hospitalised (no AD),99,0.05925888523413763,0.0029450089355844123,0.0536839263620614,0.06491398606834795 +Non-hospitalised (no AD),100,0.05919630323462208,0.0029421904019287294,0.053626679901267016,0.06484599182989659 +Non-hospitalised (no AD),101,0.058953077102324634,0.002930050387804295,0.05340643505049724,0.0645794540522004 +Non-hospitalised (no AD),102,0.05880807253458037,0.002922995178198106,0.053274786130986546,0.06442090184415958 +Non-hospitalised (no AD),103,0.05824884476222712,0.0028947026780712375,0.05276911660855563,0.06380734590351586 +Non-hospitalised (no AD),104,0.05643806458432899,0.002802833215054626,0.05113224710092026,0.06182015502931518 +Non-hospitalised (no AD),105,0.04747111402113421,0.002351835584009087,0.04301904377567188,0.05198718431632196 diff --git a/data/QALY_model/interim/long_COVID/average_QALY_losses_per_age_group.csv b/data/QALY_model/interim/long_COVID/average_QALY_losses_per_age_group.csv deleted file mode 100644 index 4c2e9eb73..000000000 --- a/data/QALY_model/interim/long_COVID/average_QALY_losses_per_age_group.csv +++ /dev/null @@ -1,41 +0,0 @@ -hospitalisation,age_group,mean,sd,lower,upper -Non-hospitalised,"[0, 12)",0.7549139354806483,0.2694793460593751,0.26033009381509126,1.2654616489762913 -Non-hospitalised,"[12, 18)",0.6557682465121549,0.2319941046629199,0.23045372285893342,1.0953384536860604 -Non-hospitalised,"[18, 25)",0.5880445016279974,0.2063723398223531,0.20999398363634544,0.9790782480476492 -Non-hospitalised,"[25, 35)",0.5091859479830138,0.1765102746143206,0.186103734244279,0.8436328969220431 -Non-hospitalised,"[35, 45)",0.42584808226184356,0.1449126549567518,0.1604649496836378,0.7004064743683598 -Non-hospitalised,"[45, 55)",0.3491923396383036,0.11581944544988457,0.1368567772399197,0.5686024656989533 -Non-hospitalised,"[55, 65)",0.27969699686034233,0.08944193486207846,0.1154619020140246,0.44910453369341524 -Non-hospitalised,"[65, 75)",0.2126266394094571,0.06400609633358172,0.09476051283649502,0.3338201724504505 -Non-hospitalised,"[75, 85)",0.14939012711229085,0.04005908402606354,0.07515845558458831,0.22519449849936593 -Non-hospitalised,"[85, 120)",0.09828109776916907,0.020763278513057953,0.05923471330586266,0.13746974820739163 -Cohort,"[0, 12)",1.947344085248101,0.8829639350355141,0.5412114592110516,3.604281750091514 -Cohort,"[12, 18)",1.6987183071446816,0.7690716896261184,0.4783040910288788,3.1482470035334598 -Cohort,"[18, 25)",1.5249729878066711,0.6887680123577957,0.434387154298585,2.8264323232466313 -Cohort,"[25, 35)",1.3175888898488481,0.5919806641239077,0.38202444758207266,2.438351224528888 -Cohort,"[35, 45)",1.0920935043268636,0.4855752793860406,0.3251580085312155,2.01155621562992 -Cohort,"[45, 55)",0.8801245695316176,0.3847321499777779,0.2717491661845526,1.6069922740029907 -Cohort,"[55, 65)",0.687311735355322,0.29289620531534105,0.2229126837437332,1.238524417668631 -Cohort,"[65, 75)",0.504013524458945,0.20608777240492873,0.17585731883702357,0.8902525649839934 -Cohort,"[75, 85)",0.33570615664482356,0.1271930468929509,0.1322131364633784,0.5737736324455484 -Cohort,"[85, 120)",0.2035409329616504,0.06606929554916093,0.09746170546937125,0.3283851787805579 -ICU,"[0, 12)",3.0458057335864352,1.1556055055051586,0.9479553850387902,5.033795329043032 -ICU,"[12, 18)",2.6483296474992724,1.0077417622788762,0.8292613202990119,4.389522587765419 -ICU,"[18, 25)",2.3712176184520075,0.9031283363394529,0.7465306849634975,3.935484401607709 -ICU,"[25, 35)",2.041279732573488,0.7765853791756424,0.6480557113435373,3.3887197036126837 -ICU,"[35, 45)",1.6835328129672527,0.6369160143929701,0.5413132363211832,2.788335483444341 -ICU,"[45, 55)",1.3479507354630411,0.5041738109373548,0.4412056820786608,2.219865106898985 -ICU,"[55, 65)",1.0427993720331827,0.3832494824727844,0.3501759277790381,1.7022073769061836 -ICU,"[65, 75)",0.752297215384547,0.2691716929942119,0.2634972701683917,1.2125534296753606 -ICU,"[75, 85)",0.484877070693285,0.16581782726261002,0.1836767039998967,0.7669847660173886 -ICU,"[85, 120)",0.2743083448199896,0.08590104372637732,0.12078862220202156,0.4206731519138677 -Non-hospitalised (no AD),"[0, 12)",0.060282821089509275,0.0031930620711356746,0.05333806424954111,0.06667994760964666 -Non-hospitalised (no AD),"[12, 18)",0.060258956115156394,0.0031930620711356768,0.05331419927518823,0.06665608263529377 -Non-hospitalised (no AD),"[18, 25)",0.06023431230082882,0.003193062071135676,0.05328955546086065,0.0666314388209662 -Non-hospitalised (no AD),"[25, 35)",0.06019667198670331,0.003193062071135676,0.05325191514673514,0.06659379850684069 -Non-hospitalised (no AD),"[35, 45)",0.06014543739797787,0.003193062071135674,0.05320068055800971,0.06654256391811524 -Non-hospitalised (no AD),"[45, 55)",0.060086650014045964,0.0031930620711356763,0.05314189317407779,0.06648377653418333 -Non-hospitalised (no AD),"[55, 65)",0.06002388450843266,0.003193062071135675,0.05307912766846448,0.06642101102857004 -Non-hospitalised (no AD),"[65, 75)",0.05995463758703485,0.003193062071135675,0.05300988074706668,0.06635176410717222 -Non-hospitalised (no AD),"[75, 85)",0.05988066945971605,0.0031930620710924457,0.05293591261984191,0.06627779597976682 -Non-hospitalised (no AD),"[85, 120)",0.05978895111949516,0.003192267062301329,0.05284592338560672,0.06618448488259096 diff --git a/data/QALY_model/interim/long_COVID/average_QALY_losses_per_age_group_SMR100.csv b/data/QALY_model/interim/long_COVID/average_QALY_losses_per_age_group_SMR100.csv new file mode 100644 index 000000000..679fd35f5 --- /dev/null +++ b/data/QALY_model/interim/long_COVID/average_QALY_losses_per_age_group_SMR100.csv @@ -0,0 +1,41 @@ +hospitalisation,age_group,mean,sd,lower,upper +Non-hospitalised,"[0, 12)",,,, +Non-hospitalised,"[12, 18)",,,, +Non-hospitalised,"[18, 25)",,,, +Non-hospitalised,"[25, 35)",,,, +Non-hospitalised,"[35, 45)",,,, +Non-hospitalised,"[45, 55)",,,, +Non-hospitalised,"[55, 65)",,,, +Non-hospitalised,"[65, 75)",,,, +Non-hospitalised,"[75, 85)",,,, +Non-hospitalised,"[85, 120)",,,, +Hospitalised (no IC),"[0, 12)",,,, +Hospitalised (no IC),"[12, 18)",,,, +Hospitalised (no IC),"[18, 25)",,,, +Hospitalised (no IC),"[25, 35)",,,, +Hospitalised (no IC),"[35, 45)",,,, +Hospitalised (no IC),"[45, 55)",,,, +Hospitalised (no IC),"[55, 65)",,,, +Hospitalised (no IC),"[65, 75)",,,, +Hospitalised (no IC),"[75, 85)",,,, +Hospitalised (no IC),"[85, 120)",,,, +Hospitalised (IC),"[0, 12)",,,, +Hospitalised (IC),"[12, 18)",,,, +Hospitalised (IC),"[18, 25)",,,, +Hospitalised (IC),"[25, 35)",,,, +Hospitalised (IC),"[35, 45)",,,, +Hospitalised (IC),"[45, 55)",,,, +Hospitalised (IC),"[55, 65)",,,, +Hospitalised (IC),"[65, 75)",,,, +Hospitalised (IC),"[75, 85)",,,, +Hospitalised (IC),"[85, 120)",,,, +Non-hospitalised (no AD),"[0, 12)",,,, +Non-hospitalised (no AD),"[12, 18)",,,, +Non-hospitalised (no AD),"[18, 25)",,,, +Non-hospitalised (no AD),"[25, 35)",,,, +Non-hospitalised (no AD),"[35, 45)",,,, +Non-hospitalised (no AD),"[45, 55)",,,, +Non-hospitalised (no AD),"[55, 65)",,,, +Non-hospitalised (no AD),"[65, 75)",,,, +Non-hospitalised (no AD),"[75, 85)",,,, +Non-hospitalised (no AD),"[85, 120)",,,, diff --git a/data/QALY_model/interim/long_COVID/average_QALY_losses_per_age_group_SMR150.csv b/data/QALY_model/interim/long_COVID/average_QALY_losses_per_age_group_SMR150.csv new file mode 100644 index 000000000..34f728f7e --- /dev/null +++ b/data/QALY_model/interim/long_COVID/average_QALY_losses_per_age_group_SMR150.csv @@ -0,0 +1,41 @@ +hospitalisation,age_group,mean,sd,lower,upper +Non-hospitalised,"[0, 12)",0.668462419110261,0.2582313828457331,0.2036324547925269,1.2266842634252282 +Non-hospitalised,"[12, 18)",0.5798944237428355,0.22187795956279144,0.18094233731503914,1.0596337319588378 +Non-hospitalised,"[18, 25)",0.5190581364867876,0.1968431158317833,0.16537131828772747,0.9447050484446313 +Non-hospitalised,"[25, 35)",0.44763489426351,0.16736730072686784,0.1471094089416646,0.8092417221722648 +Non-hospitalised,"[35, 45)",0.37120795187222455,0.13572307883109985,0.12759033988719307,0.6642768756212402 +Non-hospitalised,"[45, 55)",0.3002411506332599,0.10627491577506192,0.10947793400313126,0.5297938114190412 +Non-hospitalised,"[55, 65)",0.23622082675172743,0.07971458883081076,0.0929959256939798,0.4084045703816341 +Non-hospitalised,"[65, 75)",0.17618743525018343,0.05486694992256693,0.07783840424384207,0.29459863667090785 +Non-hospitalised,"[75, 85)",0.12206526711280687,0.03255206915706073,0.06381993641723875,0.1920038620032939 +Non-hospitalised,"[85, 120)",0.08103127670002823,0.015751336483312568,0.05284996746867399,0.1150524706145426 +Hospitalised (no IC),"[0, 12)",1.8980894392621346,0.7267827620017653,0.6207356011360611,3.4240096409038068 +Hospitalised (no IC),"[12, 18)",1.6478459932072107,0.6300813814747115,0.546874783644301,2.9726944049100523 +Hospitalised (no IC),"[18, 25)",1.472820461853593,0.5617587044599202,0.49489406166793193,2.654800869057853 +Hospitalised (no IC),"[25, 35)",1.2634184870428975,0.47914425110921366,0.4321870750253125,2.272532748393311 +Hospitalised (no IC),"[35, 45)",1.0346805795675365,0.3878601694223998,0.3623500214659087,1.8514667391139488 +Hospitalised (no IC),"[45, 55)",0.8193694351258769,0.30129304663868833,0.2966104797693478,1.4529560947554594 +Hospitalised (no IC),"[55, 65)",0.6252626513069367,0.22328391548470894,0.23728421113389478,1.0937858217247964 +Hospitalised (no IC),"[65, 75)",0.44562604115188553,0.15161325700772058,0.18080980173221772,0.7631334746039069 +Hospitalised (no IC),"[75, 85)",0.28685503228783793,0.08900307321463005,0.13044941001272536,0.4732435233307565 +Hospitalised (no IC),"[85, 120)",0.16891493919738063,0.04328019853546922,0.09158887797754195,0.2612073485364238 +Hospitalised (IC),"[0, 12)",2.9237322020738303,0.9793705841671974,1.2107236313271368,4.999388921316399 +Hospitalised (IC),"[12, 18)",2.531638312858393,0.8497821429058505,1.0519529833728634,4.331883645375432 +Hospitalised (IC),"[18, 25)",2.257562381291156,0.757962284073033,0.9411960051611258,3.8628058096578908 +Hospitalised (IC),"[25, 35)",1.9298543316512762,0.6466155391861154,0.8090419079356348,3.2987897263962442 +Hospitalised (IC),"[35, 45)",1.5721185906351458,0.5232154765316691,0.6651014247066298,2.679412531598891 +Hospitalised (IC),"[45, 55)",1.2355267693612049,0.40597563326945363,0.5298650819811873,2.094388339582217 +Hospitalised (IC),"[55, 65)",0.9320835477121102,0.3003429071567427,0.40793600939386565,1.56709365027751 +Hospitalised (IC),"[65, 75)",0.6511568673099988,0.2034594772850809,0.2948885959200651,1.0807438310262218 +Hospitalised (IC),"[75, 85)",0.4027184979804148,0.1189921363368849,0.1936167990895866,0.6530541829319151 +Hospitalised (IC),"[85, 120)",0.21808592502322638,0.057238589088626377,0.11680411982667387,0.33711143404710353 +Non-hospitalised (no AD),"[0, 12)",0.06014137527980275,0.002961992425985527,0.05453426633193338,0.06582908835826626 +Non-hospitalised (no AD),"[12, 18)",0.06011715444004468,0.002961992425985527,0.054510045492175314,0.0658048675185082 +Non-hospitalised (no AD),"[18, 25)",0.06009237832769276,0.0029619924259855273,0.05448526937982339,0.06578009140615626 +Non-hospitalised (no AD),"[25, 35)",0.06005474395604065,0.0029619924259855278,0.054447635008171284,0.06574245703450415 +Non-hospitalised (no AD),"[35, 45)",0.06000375519059451,0.002961992425985528,0.054396646242725145,0.06569146826905803 +Non-hospitalised (no AD),"[45, 55)",0.059945480395673406,0.002961992425985528,0.05433837144780404,0.06563319347413692 +Non-hospitalised (no AD),"[55, 65)",0.05988345587040076,0.002961992425985525,0.054276346922531395,0.06557116894886428 +Non-hospitalised (no AD),"[65, 75)",0.05981520268326211,0.0029619924259855247,0.054208093735392746,0.06550291576172562 +Non-hospitalised (no AD),"[75, 85)",0.05974245826449364,0.0029619924191818985,0.05413534932950368,0.06543017132989262 +Non-hospitalised (no AD),"[85, 120)",0.05963967771162379,0.0029605970042578026,0.05403521032407272,0.06532471125642572 diff --git a/data/covid19_DTM/interim/sciensano/vacc_incidence_national.pkl b/data/covid19_DTM/interim/sciensano/vacc_incidence_national.pkl index bc0b8f29a..55f095e20 100644 Binary files a/data/covid19_DTM/interim/sciensano/vacc_incidence_national.pkl and b/data/covid19_DTM/interim/sciensano/vacc_incidence_national.pkl differ diff --git a/notebooks/analysis/woldmuyn_long_COVID.py b/notebooks/analysis/woldmuyn_long_COVID.py index 1346733de..311e5c635 100644 --- a/notebooks/analysis/woldmuyn_long_COVID.py +++ b/notebooks/analysis/woldmuyn_long_COVID.py @@ -38,8 +38,6 @@ ## Define simulation settings ## ################################ - # Number of simulations - #N=50 # Number of neg. binomial draws/ simulation K=10 # Number of cpu's @@ -47,7 +45,7 @@ # Number of age groups age_stratification_size=10 # End of simulation - end_sim='2021-12-31' + end_sim='2021-07-01' # Confidence level used to visualise model fit conf_int=0.05 @@ -116,14 +114,12 @@ ax.grid(False) ax.tick_params(axis='both', which='major', labelsize=10) ax.tick_params(axis='x', which='major', rotation=30) - ax.set_ylim([0,7000]) + ax.set_ylim([0,6600]) axes[0].legend(loc=2, framealpha=1, fontsize=10) axes[0].set_ylabel('QALYs lost per 100K inhab.', size=10) plt.tight_layout() - plt.show() - fig.savefig('QALY_losses_per_age_group.pdf') - plt.close() + fig.savefig(result_folder+'QALY_losses_per_age_group.pdf') # Wolf's code starts here label_font = font_manager.FontProperties(family='CMU Sans Serif', @@ -206,6 +202,6 @@ lower = np.quantile(total,0.025) upper = np.quantile(total,0.975) - QALY_table[total_label]['Total'] = f'{mean:.0f}\n({lower:.0f};{upper:.0f})' + QALY_table[total_label]['Total'] = f'{mean:.0f}\n({lower:.0f}; {upper:.0f})' QALY_table.to_csv(os.path.join(result_folder,f'Long_COVID_summary_SMR{SMR*100:.0f}.csv')) \ No newline at end of file diff --git a/notebooks/preprocessing/woldmuyn_long_covid_average_QALY_loss.py b/notebooks/preprocessing/woldmuyn_long_covid_average_QALY_loss.py index a9109227d..47411bffc 100644 --- a/notebooks/preprocessing/woldmuyn_long_covid_average_QALY_loss.py +++ b/notebooks/preprocessing/woldmuyn_long_covid_average_QALY_loss.py @@ -97,14 +97,6 @@ # results # # ------- # -# latex font -label_font = font_manager.FontProperties(family='CMU Sans Serif', - style='normal', - size=10) -legend_font = font_manager.FontProperties(family='CMU Sans Serif', - style='normal', - size=8) - # result folders data_result_folder = '../../data/QALY_model/interim/long_COVID/' fig_result_folder = '../../results/QALY_model/direct_QALYs/prepocessing/' @@ -247,7 +239,7 @@ def log_probability(theta, tau, x, y, bounds): ) samplers.update({hospitalisation:sampler}) # run sampler - sampler.run_mcmc(pos, 25000, progress=True) + sampler.run_mcmc(pos, 50000, progress=True) # extract chains flat_samples = sampler.get_chain(discard=5000, thin=100, flat=True) # print results @@ -256,6 +248,8 @@ def log_probability(theta, tau, x, y, bounds): p_AD_summary['lower'][hospitalisation] = np.quantile(flat_samples,0.025,axis=0) p_AD_summary['upper'][hospitalisation] = np.quantile(flat_samples,0.975,axis=0) +print(p_AD_summary) + # visualise MCMC results fig,axes = plt.subplots(nrows=1,ncols=3,figsize=(8.3,0.25*11.7),sharey=True) @@ -305,8 +299,8 @@ def log_probability(theta, tau, x, y, bounds): ax.set_xlabel('Age (years)',size=10) ax.set_ylabel('QoL (-)',size=10) ax.set_ylim([0.5, 0.9]) -ax.grid(False) ax.tick_params(axis='both', which='major', labelsize=10) +ax.grid(False) plt.tight_layout() fig.savefig(os.path.join(abs_dir,fig_result_folder,'QoL_Belgium_fit.pdf')) @@ -323,7 +317,7 @@ def QALY_loss_func(t,tau,p_AD,age,QoL_after): beta = QoL_Belgium_func(age+t/12)-QoL_after return prevalence_func(t,tau,p_AD) * max(0,beta) -draws = 1000 +draws = 500 # Pre-allocate new multi index series with index=hospitalisation,age,draw multi_index = pd.MultiIndex.from_product([hospitalisation_groups+['Non-hospitalised (no AD)'],np.arange(draws),LE_table.index.values],names=['hospitalisation','draw','age']) @@ -351,8 +345,8 @@ def QALY_loss_func(t,tau,p_AD,age,QoL_after): QoL_after = QoL_Belgium_func(age)-beta # integrate QALY_loss_func from 0 to LE (OPM: kan ook discreet) QALY_loss = quad(QALY_loss_func,0,LE,args=(tau,p_AD,age,QoL_after))[0]/12 - average_QALY_losses.iloc[idx] = QALY_loss - + average_QALY_losses_per_age.iloc[idx] = QALY_loss + print('\n(4.2) Bin average QALY loss per age to age groups\n') # bin data @@ -394,13 +388,12 @@ def get_sd(x): print('\n(6) Visualise results\n') -# Visualise results (TWA) +# QALY loss per age group fig,axes = plt.subplots(nrows=1,ncols=3,figsize=(8.3,0.25*11.7),sharey=True) - for ax,hospitalisation in zip(axes,hospitalisation_groups): - mean = average_QALY_losses_summary.loc[hospitalisation]['mean'] - lower = average_QALY_losses_summary.loc[hospitalisation]['lower'] - upper = average_QALY_losses_summary.loc[hospitalisation]['upper'] + mean = average_QALY_losses_per_age_summary.loc[hospitalisation]['mean'] + lower = average_QALY_losses_per_age_summary.loc[hospitalisation]['lower'] + upper = average_QALY_losses_per_age_summary.loc[hospitalisation]['upper'] ax.plot(LE_table.index.values,mean,color='black',linewidth=1.5, linestyle='--') ax.plot(LE_table.index.values,lower,color='black',linewidth=1, linestyle='-') ax.plot(LE_table.index.values,upper,color='black',linewidth=1, linestyle='-') @@ -413,42 +406,24 @@ def get_sd(x): plt.tight_layout() fig.savefig(os.path.join(abs_dir,fig_result_folder,'average_QALY_losses_per_age.pdf')) -# Visualise results (WD) -fig,axs = plt.subplots(1,3,figsize=(6,2.5),sharey=True,sharex=True) -for ax,hospitalisation in zip(axs,hospitalisation_groups): - mean = average_QALY_losses_per_age_summary.loc[hospitalisation]['mean'] - lower = average_QALY_losses_per_age_summary.loc[hospitalisation]['lower'] - upper = average_QALY_losses_per_age_summary.loc[hospitalisation]['upper'] - ax.plot(LE_table.index.values,mean,color=palette_colors[color_dict[hospitalisation]],linestyle='--',label=f'{hospitalisation}',linewidth=1) - ax.fill_between(LE_table.index.values,lower,upper,alpha=0.20, color=palette_colors[color_dict[hospitalisation]]) - - ax.grid(False) - ax.set_xlabel('Age when infected (years)',font=label_font) - ax.tick_params(axis='both', which='major', labelsize=8) - ax.set_title(hospitalisation,font=label_font) - -axs[0].set_ylabel('Average QALY loss',font=label_font) -fig.tight_layout() -fig.savefig(os.path.join(abs_dir,fig_result_folder,f'average_QALY_losses_per_age_SMR{SMR*100:.0f}.png'),dpi=600,bbox_inches='tight') - # QALY losses due COVID death fig,ax = plt.subplots(figsize=(5,3)) -ax.plot(Life_table.compute_QALY_D_x(r=0,SMR=SMR),color=palette_colors['black'],label=r'$r=0\%$',linewidth=2) -ax.plot(Life_table.compute_QALY_D_x(r=0.03,SMR=SMR),color=palette_colors['black'],linestyle=':',label=r'$r=3\%$',linewidth=2) +ax.plot(Life_table.compute_QALY_D_x(r=0,SMR=SMR),color='black',label=r'$r=0\%$',linewidth=2) +ax.plot(Life_table.compute_QALY_D_x(r=0.03,SMR=SMR),color='black',linestyle=':',label=r'$r=3\%$',linewidth=2) ax.grid(False) -ax.set_xlabel('Age (years)',font=label_font) -ax.set_ylabel(r'$QALY_D$',font=label_font) +ax.set_xlabel('Age (years)') +ax.set_ylabel(r'$QALY_D$') ax.tick_params(axis='both', which='major', labelsize=8) -ax.legend(prop=legend_font) +ax.legend() fig.tight_layout() -fig.savefig(os.path.join(abs_dir,fig_result_folder,f'QALY_D_SMR{SMR*100:.0f}.png'),dpi=600,bbox_inches='tight') +fig.savefig(os.path.join(abs_dir,fig_result_folder,f'QALY_D_SMR{SMR*100:.0f}.pdf'),dpi=600,bbox_inches='tight') # Life expectancy fig,ax = plt.subplots(figsize=(3,3)) ax.plot(LE_table,'black',linewidth=1.5) ax.grid(False) -ax.set_ylabel('Life expectancy (years)',font=label_font) -ax.set_xlabel('Age (years)',font=label_font) +ax.set_ylabel('Life expectancy (years)') +ax.set_xlabel('Age (years)') ax.tick_params(axis='both', which='major', labelsize=8) fig.tight_layout() -fig.savefig(os.path.join(abs_dir,fig_result_folder,f'LE_SMR{SMR*100:.0f}.png'),dpi=600,bbox_inches='tight') \ No newline at end of file +fig.savefig(os.path.join(abs_dir,fig_result_folder,f'LE_SMR{SMR*100:.0f}.pdf'),dpi=600,bbox_inches='tight') \ No newline at end of file diff --git a/results/QALY_model/direct_QALYs/analysis/Long_COVID_summary.csv b/results/QALY_model/direct_QALYs/analysis/Long_COVID_summary.csv deleted file mode 100644 index b3acab8e9..000000000 --- a/results/QALY_model/direct_QALYs/analysis/Long_COVID_summary.csv +++ /dev/null @@ -1,89 +0,0 @@ -,Non-hospitalised (no AD),Non-hospitalised (AD),Cohort,ICU,Deaths,Total (no AD),Total (AD) -0-12,"13423 -(12015;14930)","157452 -(49854;274172)","3873 -(894;7006)","166 -(63;312)","0 -(0;0)","17462 -(13893;21468)","161491 -(53118;278452)" -12-18,"6751 -(6057;7499)","68913 -(22364;119343)","1487 -(348;2690)","305 -(131;521)","502 -(245;796)","9045 -(7620;10774)","71208 -(24414;121733)" -18-25,"5288 -(4711;5898)","48488 -(16000;83893)","1420 -(332;2589)","244 -(104;405)","0 -(0;0)","6951 -(5643;8433)","50151 -(17101;85632)" -25-35,"9130 -(8144;10203)","72651 -(24379;126004)","3566 -(846;6414)","531 -(217;913)","2276 -(1328;3406)","15502 -(12285;19277)","79023 -(30135;132496)" -35-45,"11919 -(10635;13240)","79551 -(27815;136155)","4253 -(1053;7658)","1025 -(420;1744)","4989 -(3533;6750)","22185 -(18003;26470)","89817 -(37157;146527)" -45-55,"11049 -(9846;12345)","60648 -(22096;103103)","6004 -(1562;10787)","2016 -(863;3403)","11183 -(8247;14077)","30253 -(24484;36381)","79852 -(40741;123085)" -55-65,"7155 -(6351;8005)","31563 -(12213;52503)","5368 -(1427;9478)","2487 -(1105;4157)","21750 -(18206;25285)","36760 -(31298;43337)","61168 -(40315;82328)" -65-75,"2705 -(2399;3047)","9111 -(3847;14696)","5946 -(1784;10449)","3162 -(1449;5088)","45420 -(40089;50999)","57233 -(49661;64739)","63640 -(54108;73470)" -75-85,"926 -(812;1052)","2208 -(1072;3427)","4248 -(1491;7195)","1382 -(637;2239)","52241 -(47264;57450)","58796 -(52750;64975)","60079 -(53991;66113)" -85+,"462 -(405;525)","735 -(434;1053)","1421 -(597;2318)","99 -(49;164)","19288 -(17760;20972)","21270 -(19371;23250)","21543 -(19687;23538)" -Total,"68807 -(61355;76777)","531321 -(180293;914343)","37586 -(10347;66245)","11416 -(5105;18499)","157649 -(146532;170026)","275458 -(240383;313122)","737971 -(381697;1120947)" diff --git a/results/QALY_model/direct_QALYs/analysis/Long_COVID_summary_SMR100.csv b/results/QALY_model/direct_QALYs/analysis/Long_COVID_summary_SMR100.csv new file mode 100644 index 000000000..e98cae007 --- /dev/null +++ b/results/QALY_model/direct_QALYs/analysis/Long_COVID_summary_SMR100.csv @@ -0,0 +1,89 @@ +,Non-hospitalised (no AD),Non-hospitalised (AD),Cohort,ICU,Deaths,Total (no AD),Total (AD) +0-12,"8308 +(7215;9355)","95784 +(22162;176321)","1809 +(412;3191)","76 +(23;151)","0 +(0;0)","10193 +(8370;11783)","97628 +(23766;179274)" +12-18,"4621 +(4014;5190)","46361 +(11042;84891)","804 +(185;1417)","164 +(59;297)","276 +(137;488)","5865 +(4997;6633)","47583 +(12200;86664)" +18-25,"3757 +(3185;4296)","33873 +(8215;61977)","877 +(204;1554)","153 +(51;274)","0 +(0;0)","4787 +(3891;5629)","34879 +(9154;63328)" +25-35,"6624 +(5627;7564)","51835 +(13067;94287)","2262 +(532;3944)","338 +(122;592)","1474 +(705;2314)","10698 +(8604;12568)","55851 +(16701;99231)" +35-45,"8521 +(7358;9644)","55925 +(14930;100931)","2716 +(669;4743)","662 +(229;1169)","3036 +(2217;3870)","14935 +(12332;17318)","62262 +(20907;107712)" +45-55,"8223 +(7006;9394)","44403 +(12645;79253)","4006 +(1020;6876)","1351 +(470;2344)","7550 +(5781;9224)","21131 +(17319;24750)","57185 +(24322;93054)" +55-65,"4806 +(3960;5570)","20871 +(6446;36750)","3326 +(931;5678)","1554 +(605;2636)","13606 +(11656;15580)","23292 +(19967;26568)","39240 +(23523;55949)" +65-75,"1796 +(1398;2145)","5964 +(2059;10296)","3760 +(1144;6285)","1970 +(738;3282)","29139 +(25712;33036)","36665 +(31782;41731)","40704 +(33922;47521)" +75-85,"512 +(361;662)","1205 +(477;2037)","2261 +(815;3735)","738 +(314;1239)","28582 +(24175;31180)","32093 +(27607;35359)","32726 +(27980;36010)" +85+,"281 +(199;365)","442 +(216;690)","742 +(334;1141)","52 +(25;86)","10232 +(8738;11191)","11307 +(9693;12454)","11457 +(9711;12570)" +Total,"47449 +(40499;54165)","356664 +(91264;647881)","22563 +(6251;38517)","7057 +(2635;11902)","93895 +(82929;101095)","170965 +(148203;191242)","479515 +(209211;779571)" diff --git a/results/QALY_model/direct_QALYs/analysis/Long_COVID_summary_SMR150.csv b/results/QALY_model/direct_QALYs/analysis/Long_COVID_summary_SMR150.csv new file mode 100644 index 000000000..377564f61 --- /dev/null +++ b/results/QALY_model/direct_QALYs/analysis/Long_COVID_summary_SMR150.csv @@ -0,0 +1,89 @@ +,Non-hospitalised (no AD),Non-hospitalised (AD),Cohort,ICU,Deaths,Total (no AD),Total (AD) +0-12,"8270 +(7280;9352)","90236 +(14582;157711)","1794 +(432;3082)","73 +(20;140)","0 +(0;0)","10136 +(8429;11889)","92079 +(16423;159442)" +12-18,"4599 +(4054;5177)","43563 +(7403;75963)","792 +(191;1351)","158 +(43;277)","254 +(125;416)","5804 +(4968;6680)","44756 +(8526;77025)" +18-25,"3739 +(3248;4278)","31716 +(5667;54786)","861 +(209;1480)","147 +(40;256)","0 +(0;0)","4748 +(3934;5613)","32712 +(6479;55825)" +25-35,"6593 +(5730;7541)","48277 +(9210;82875)","2210 +(539;3785)","319 +(83;546)","1358 +(841;1959)","10480 +(8406;12473)","52132 +(12573;86823)" +35-45,"8483 +(7444;9686)","51582 +(10766;87745)","2620 +(666;4434)","606 +(164;1020)","2981 +(2129;3902)","14689 +(12072;16967)","57748 +(16660;93621)" +45-55,"8186 +(7102;9419)","40321 +(9461;67807)","3804 +(1002;6433)","1231 +(356;2044)","6784 +(4865;8396)","20005 +(16666;23280)","52078 +(20886;79521)" +55-65,"4783 +(4088;5562)","18573 +(4998;30583)","3069 +(866;5172)","1398 +(411;2330)","12027 +(10026;14919)","21277 +(17736;24985)","35015 +(21034;48394)" +65-75,"1786 +(1486;2126)","5186 +(1670;8394)","3366 +(1100;5565)","1738 +(575;2832)","24676 +(22406;27343)","31566 +(27673;35399)","34910 +(29820;40108)" +75-85,"507 +(392;630)","1024 +(417;1650)","1976 +(764;3156)","610 +(223;993)","22990 +(20883;25499)","26084 +(23459;28960)","26575 +(23632;29661)" +85+,"278 +(215;346)","375 +(206;556)","621 +(301;956)","41 +(18;71)","7839 +(7043;8729)","8779 +(7932;9755)","8870 +(7957;9836)" +Total,"47225 +(41067;54111)","330853 +(64709;566318)","21113 +(6043;35368)","6321 +(1913;10391)","78909 +(72366;85375)","153568 +(134389; 173180)","436876 +(166479; 673679)" diff --git a/results/QALY_model/direct_QALYs/analysis/QALY_losses_per_age_group.pdf b/results/QALY_model/direct_QALYs/analysis/QALY_losses_per_age_group.pdf new file mode 100644 index 000000000..33e3197d6 Binary files /dev/null and b/results/QALY_model/direct_QALYs/analysis/QALY_losses_per_age_group.pdf differ diff --git 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differ diff --git a/results/QALY_model/direct_QALYs/prepocessing/prevalence_MCMC_fit.png b/results/QALY_model/direct_QALYs/prepocessing/prevalence_MCMC_fit.png deleted file mode 100644 index dd86d0bcf..000000000 Binary files a/results/QALY_model/direct_QALYs/prepocessing/prevalence_MCMC_fit.png and /dev/null differ diff --git a/results/QALY_model/direct_QALYs/prepocessing/prevalence_first_fit.pdf b/results/QALY_model/direct_QALYs/prepocessing/prevalence_first_fit.pdf new file mode 100644 index 000000000..a4fb090e1 Binary files /dev/null and b/results/QALY_model/direct_QALYs/prepocessing/prevalence_first_fit.pdf differ diff --git a/results/QALY_model/direct_QALYs/prepocessing/prevalence_first_fit_AD.png b/results/QALY_model/direct_QALYs/prepocessing/prevalence_first_fit_AD.png deleted file mode 100644 index f2dd5be7e..000000000 Binary files a/results/QALY_model/direct_QALYs/prepocessing/prevalence_first_fit_AD.png and /dev/null differ diff --git a/results/QALY_model/direct_QALYs/prepocessing/prevalence_first_fit_no_AD.png b/results/QALY_model/direct_QALYs/prepocessing/prevalence_first_fit_no_AD.png deleted file mode 100644 index 84c10f03b..000000000 Binary files a/results/QALY_model/direct_QALYs/prepocessing/prevalence_first_fit_no_AD.png and /dev/null differ diff --git a/src/QALY_model/__pycache__/direct_QALYs.cpython-310.pyc b/src/QALY_model/__pycache__/direct_QALYs.cpython-310.pyc index e621651be..bac8351df 100644 Binary files a/src/QALY_model/__pycache__/direct_QALYs.cpython-310.pyc and b/src/QALY_model/__pycache__/direct_QALYs.cpython-310.pyc differ diff --git a/src/QALY_model/direct_QALYs.py b/src/QALY_model/direct_QALYs.py index 55ae4f1ec..b2cbaaa7c 100644 --- a/src/QALY_model/direct_QALYs.py +++ b/src/QALY_model/direct_QALYs.py @@ -467,13 +467,13 @@ def lost_QALYs(out,AD_non_hospitalised=False,SMR=1,draws=500): out_enlarged = xr.concat([out]*int(np.ceil(500/sim_draws)), dim='draws') if AD_non_hospitalised: - hospitalisation_groups = ['Non-hospitalised','Cohort','ICU'] + hospitalisation_groups = ['Non-hospitalised','Hospitalised (no IC)','Hospitalised (IC)'] else: - hospitalisation_groups = ['Non-hospitalised (no AD)','Cohort','ICU'] + hospitalisation_groups = ['Non-hospitalised (no AD)','Hospitalised (no IC)','Hospitalised (IC)'] # Load average QALY losses abs_dir = os.path.dirname(__file__) - rel_dir = '../../../data/covid19_DTM/interim/QALY_model/long_COVID/' + rel_dir = '../../data/QALY_model/interim/long_COVID/' file_name = f'average_QALY_losses_per_age_group_SMR{SMR*100:.0f}.csv' average_QALY_losses = pd.read_csv(os.path.join(abs_dir,rel_dir,file_name),index_col=[0,1]) age_groups = average_QALY_losses.index.get_level_values('age_group').unique()