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Error running frem with option -model_subdir #263

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hugo-maas opened this issue Sep 4, 2024 · 0 comments
Open

Error running frem with option -model_subdir #263

hugo-maas opened this issue Sep 4, 2024 · 0 comments

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@hugo-maas
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So far tested this with PsN 5.3.1 and 5.4.0

frem run1.mod -covariates=APGR -clean=0 -model_subdir
Fitting the base model.
Starting 1 NONMEM executions. 1 in parallel.
S:1 .. 
All executions started.
F:1 .. 
 Trying to load output but output object is empty, file
<projectdir>/run1/frem_dir1/m1/model_1.lst
 
The number of problems are not the same in from-output <projectdir>/run1/frem_dir1/m1/model_1.lst  (0) and the model to be updated <projectdir>/run1/frem_dir1/m1/model_1.mod (1) at <psndir>/tool/frem.pm line 1131.

Whereas running without -model_subdir, models are evaluated as expected.

frem run1.mod -covariates=APGR -clean=0 -no-model_subdir
Fitting the base model.
Starting 1 NONMEM executions. 1 in parallel.
S:1 .. 
All executions started.
F:1 .. Running evaluation to filter data and add FREMTYPE for FREM data set
Starting 1 NONMEM executions. 1 in parallel.
S:1 .. 
All executions started.
F:1 .. 
Warning: The covariate covariance matrix has 1 (essentially) non-positive
eigenvalue(s). Modified Model 2 covariate $OMEGA block to make is positive
definite.
Evaluating model 2
Starting 1 NONMEM executions. 1 in parallel.
S:1 .. 
All executions started.
F:1 .. Evaluating model 3
Starting 1 NONMEM executions. 1 in parallel.
S:1 .. 
All executions started.
F:1 .. Evaluating model 3b
Starting 1 NONMEM executions. 1 in parallel.
S:1 .. 
All executions started.
F:1 .. Starting model4 from model3b
Estimating model 4
Starting 1 NONMEM executions. 1 in parallel.
S:1 .. 
All executions started.
F:1 .. printed proposal_density.cov for sir -covmat_input option
frem done
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