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Xenophong committed Mar 27, 2024
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Expand Up @@ -401,7 +401,7 @@ <h1>A list of my academic contributions.</h1>
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<a href="">Under Review, 2024</a>
<a href="">(Manuscript in preparation), 2024</a>
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<h4 class="h02"><a href="">Tissue Specific Regulation of Mitochondria Encoding Genes.</a></h4>
</p>By using linear mixed models (LMMs) and conducting expression quantitative locus (eQTL) mapping, we explored the crosstalk between mitochondria and the cell nucleus across 48 different tissues. Through the integration of our identified eQTLs with various molecular data types like mutation rates, gene expression, and protein-protein interaction data, we applied mendelian randomization, mediation, statistical colocalization, and graph neural networks to unravel the established associations. Our study shows potential for unveiling new therapeutic approaches aimed at a wide range of diseases, from metabolic disorders to neurodegenerative conditions.<p>
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