From 6df08c55805fd6486ef80b01865b20500b9acedb Mon Sep 17 00:00:00 2001
From: andrewhooker Giulia Lestini,
Martin Fink and Andrew Hooker
- 15 November, 2023
Source: vignettes/examples.Rmd
examples.Rmd
ODE solution of PK model, mult
of describing the same model.
tic(); eval <- evaluate_design(poped.db); toc()
-#> Elapsed time: 2.804 seconds.
+#> Elapsed time: 2.812 seconds.
tic(); eval <- evaluate_design(poped.db.Rcpp); toc()
-#> Elapsed time: 1.353 seconds.
The difference is noticeable and gets larger for more complex ODE models.
@@ -1130,7 +1129,7 @@
ev <- evaluate_design(poped_db_2)
round(ev$ofv,1)
-#> [1] 41.8
+#> [1] 42
round(ev$rse)
vignettes/articles/handling_LOQ.Rmd
handling_LOQ.Rmd
The D2 nmethod is the same as removing the last data point
@@ -394,8 +393,8 @@ULOQ handlinglibrary(ggplot2) plot_model_prediction(poped_db, model_num_points = 500,facet_scales = "free", PI=T, PI_alpha = 0.1) + - geom_hline(yintercept = 2,color="red",linetype="dotted") + - geom_hline(yintercept = 7,color="blue",linetype="dotted")
eval_ul_D6 <-evaluate_design(poped_db,
diff --git a/articles/handling_LOQ_files/figure-html/unnamed-chunk-9-1.png b/articles/handling_LOQ_files/figure-html/unnamed-chunk-9-1.png
index 40667a9570ea30b85f429ec1daea39def7b7aaff..763264039c73e8ca953e1c946c5af932a43135d9 100644
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