diff --git a/.Rbuildignore b/.Rbuildignore index 2e9e1dd..007d6cd 100644 --- a/.Rbuildignore +++ b/.Rbuildignore @@ -6,9 +6,8 @@ ^.*\.sh$ ^tests$ ^data-raw$ -^packrat/ ^\.Rprofile$ ^README.*$ -^Figures$ -^rd2pdf\.sh$ +^assets$ +^Makefile$ ^docs$ diff --git a/Figures/MyPlotMultiMyConcTimeMulti-1.png b/Figures/MyPlotMultiMyConcTimeMulti-1.png deleted file mode 100644 index 9007a18..0000000 Binary files a/Figures/MyPlotMultiMyConcTimeMulti-1.png and /dev/null differ diff --git a/Figures/MyPlotMultiPub-1.png b/Figures/MyPlotMultiPub-1.png deleted file mode 100644 index 24c4694..0000000 Binary files a/Figures/MyPlotMultiPub-1.png and /dev/null differ diff --git a/Figures/MyPlotMyConcTime-1.png b/Figures/MyPlotMyConcTime-1.png deleted file mode 100644 index 3035d82..0000000 Binary files a/Figures/MyPlotMyConcTime-1.png and /dev/null differ diff --git a/Figures/MyPlotPub-1.png b/Figures/MyPlotPub-1.png deleted file mode 100644 index 732198d..0000000 Binary files a/Figures/MyPlotPub-1.png and /dev/null differ diff --git a/Makefile b/Makefile new file mode 100644 index 0000000..af942a9 --- /dev/null +++ b/Makefile @@ -0,0 +1,5 @@ +rd2pdf: + rm caffsim.pdf;R CMD rd2pdf ../caffsim + +pkgdown: + rm -rf docs;Rscript -e "Sys.setlocale('LC_ALL', 'C'); pkgdown::build_site()" diff --git a/NAMESPACE b/NAMESPACE index 56aa77c..530588a 100644 --- a/NAMESPACE +++ b/NAMESPACE @@ -1,11 +1,11 @@ # Generated by roxygen2: do not edit by hand -export(ConcTime) -export(ConcTimeMulti) -export(Dataset) -export(DatasetMulti) -export(Plot) -export(PlotMulti) +export(caffConcTime) +export(caffConcTimeMulti) +export(caffDataset) +export(caffDatasetMulti) +export(caffPlot) +export(caffPlotMulti) import(dplyr) import(ggplot2) importFrom(mgcv,rmvn) diff --git a/R.Rproj b/R.Rproj index e45dcec..c28a1cc 100644 --- a/R.Rproj +++ b/R.Rproj @@ -6,7 +6,7 @@ AlwaysSaveHistory: Yes EnableCodeIndexing: Yes UseSpacesForTab: Yes -NumSpacesForTab: 4 +NumSpacesForTab: 2 Encoding: UTF-8 RnwWeave: knitr diff --git a/R/ConcTime.R b/R/ConcTime.R index 75de4db..de2e8b3 100644 --- a/R/ConcTime.R +++ b/R/ConcTime.R @@ -1,6 +1,6 @@ -#' Create a dataset of the concentration-time curve +#' Create a dataset of the concentration-time curve of single oral administration of caffeine #' -#' \code{ConcTime} will create a dataset of the concentration-time curve +#' \code{caffConcTime} will create a dataset of the concentration-time curve #' #' @param Weight Body weight (kg) #' @param Dose Dose of single caffeine (mg) @@ -8,29 +8,29 @@ #' @return The dataset of concentration and time of simulated subjects #' @export #' @examples -#' ConcTime(Weight = 20, Dose = 200, N = 20) -#' ConcTime(20, 200) -#' @seealso \url{http://asancpt.github.io/CaffeineEdison} +#' caffConcTime(Weight = 20, Dose = 200, N = 20) +#' caffConcTime(20, 200) #' @import dplyr +#' @seealso \url{https://asancpt.github.io/caffsim} -ConcTime <- function(Weight, Dose, N = 20){ - #set.seed(Seed) - ggConc <- Dataset(Weight, Dose, N) %>% - select(CL, V, Ka, Ke) %>% - mutate(Subject = row_number()) %>% - left_join(expand.grid( - x = seq(1, N, length.out = N), #Subjecti - y = seq(0,24, by = 0.1)) %>% # Time - select(Subject=x, Time=y), by = "Subject") %>% - mutate(Conc = Dose / V * Ka / (Ka - Ke) * (exp(-Ke * Time) - exp(-Ka * Time))) %>% - select(Subject, Time, Conc) - return(ggConc) +caffConcTime <- function(Weight, Dose, N = 20){ + #set.seed(Seed) + ggConc <- caffDataset(Weight, Dose, N) %>% + select(CL, V, Ka, Ke) %>% + mutate(Subject = row_number()) %>% + left_join(expand.grid( + x = seq(1, N, length.out = N), #Subjecti + y = seq(0,24, by = 0.1)) %>% # Time + select(Subject=x, Time=y), by = "Subject") %>% + mutate(Conc = Dose / V * Ka / (Ka - Ke) * (exp(-Ke * Time) - exp(-Ka * Time))) %>% + select(Subject, Time, Conc) + return(ggConc) } -#' Create a dataset of the concentration-time curve of multiple dosing +#' Create a dataset of the concentration-time curve of multiple dosing of caffeine #' -#' \code{ConcTimeMulti} will create a dataset of the concentration-time curve of multiple dosing +#' \code{caffConcTimeMulti} will create a dataset of the concentration-time curve of multiple oral administrations of caffeine #' #' @param Weight Body weight (kg) #' @param Dose Dose of single caffeine (mg) @@ -40,31 +40,33 @@ ConcTime <- function(Weight, Dose, N = 20){ #' @return The dataset of concentration and time of simulated subjects of multiple dosing #' @export #' @examples -#' ConcTimeMulti(Weight = 20, Dose = 200, N = 20, Tau = 8, Repeat = 4) -#' ConcTimeMulti(20, 200) -#' @seealso \url{http://asancpt.github.io/CaffeineEdison} +#' caffConcTimeMulti(Weight = 20, Dose = 200, N = 20, Tau = 8, Repeat = 4) +#' caffConcTimeMulti(20, 200) #' @import dplyr +#' @seealso \url{https://asancpt.github.io/caffsim} -ConcTimeMulti <- function(Weight, Dose, N = 20, Tau = 8, Repeat = 4){ - Subject <- seq(1, N, length.out = N) # - Time <- seq(0, 96, length.out = 481) # - Grid <- expand.grid(x = Subject, y = Time) %>% select(Subject=x, Time=y) - - ggsuper <- Dataset(Weight, Dose, N) %>% select(CL, V, Ka, Ke) %>% - mutate(Subject = row_number()) %>% - left_join(Grid, by = "Subject") %>% - mutate(Conc = Dose / V * Ka / (Ka - Ke) * (exp(-Ke * Time) - exp(-Ka * Time))) %>% - group_by(Subject) %>% - mutate(ConcOrig = Conc, - ConcTemp = 0) - ## Superposition - for (i in 1:Repeat){ - Frame <- Tau * 5 * i - ggsuper <- ggsuper %>% - mutate(Conc = Conc + ConcTemp) %>% - mutate(ConcTemp = lag(ConcOrig, n = Frame, default = 0)) - } - - ggsuper <- ggsuper %>% select(Subject, Time, Conc) - return(ggsuper) +caffConcTimeMulti <- function(Weight, Dose, N = 20, Tau = 8, Repeat = 4){ + Subject <- seq(1, N, length.out = N) # + Time <- seq(0, 96, length.out = 481) # + Grid <- expand.grid(x = Subject, y = Time) %>% select(Subject=x, Time=y) + + ggsuper <- caffDataset(Weight, Dose, N) %>% + select(CL, V, Ka, Ke) %>% + mutate(Subject = row_number()) %>% + left_join(Grid, by = "Subject") %>% + mutate(Conc = Dose / V * Ka / (Ka - Ke) * (exp(-Ke * Time) - exp(-Ka * Time))) %>% + group_by(Subject) %>% + mutate(ConcOrig = Conc, + ConcTemp = 0) + + ## Superposition + for (i in 1:Repeat){ + Frame <- Tau * 5 * i + ggsuper <- ggsuper %>% + mutate(Conc = Conc + ConcTemp) %>% + mutate(ConcTemp = lag(ConcOrig, n = Frame, default = 0)) + } + + ggsuper <- ggsuper %>% select(Subject, Time, Conc) + return(ggsuper) } diff --git a/R/Dataset.R b/R/Dataset.R index b14621b..65ddc93 100644 --- a/R/Dataset.R +++ b/R/Dataset.R @@ -1,6 +1,6 @@ #' Create a dataset for simulation of single dose of caffeine #' -#' \code{Dataset} will create a dataset for simulation of single dose of caffeine +#' \code{caffDataset} will create a dataset for simulation of single dose of caffeine #' #' @param Weight Body weight (kg) #' @param Dose Dose of single caffeine (mg) @@ -8,14 +8,14 @@ #' @return The dataset of pharmacokinetic parameters of subjects after single caffeine dose following multivariate normal #' @export #' @examples -#' Dataset(Weight = 20, Dose = 200, N = 20) -#' Dataset(20,500) -#' @seealso \url{http://asancpt.github.io/CaffeineEdison} +#' caffDataset(Weight = 20, Dose = 200, N = 20) +#' caffDataset(20,500) #' @importFrom mgcv rmvn #' @import dplyr +#' @seealso \url{https://asancpt.github.io/caffsim} -Dataset <- function(Weight, Dose, N = 20){ - MVN <- rmvn(N, CaffMu, CaffSigma); +caffDataset <- function(Weight, Dose, N = 20){ + MVN <- mgcv::rmvn(N, CaffMu, CaffSigma) MVNdata <- data.frame(MVN, stringsAsFactors = FALSE) %>% select(eta1 = X1, eta2 = X2, eta3 = X3) %>% mutate(CL = 0.09792 * Weight * exp(eta1), # L/hr @@ -31,7 +31,7 @@ Dataset <- function(Weight, Dose, N = 20){ #' Create a dataset for simulation of multiple dose of caffeine #' -#' \code{DatasetMulti} will create a dataset for simulation of multiple dose of caffeine +#' \code{caffDatasetMulti} will create a dataset for simulation of multiple dose of caffeine #' #' @param Weight Body weight (kg) #' @param Dose Dose of multiple caffeine (mg) @@ -40,32 +40,31 @@ Dataset <- function(Weight, Dose, N = 20){ #' @return The dataset of pharmacokinetic parameters of subjects after multiple caffeine dose following multivariate normal #' @export #' @examples -#' DatasetMulti(Weight = 20, Dose = 200, N = 20, Tau = 8) -#' DatasetMulti(20,500) -#' @seealso \url{http://asancpt.github.io/CaffeineEdison} +#' caffDatasetMulti(Weight = 20, Dose = 200, N = 20, Tau = 8) +#' caffDatasetMulti(20,500) #' @importFrom mgcv rmvn #' @import dplyr +#' @seealso \url{https://asancpt.github.io/caffsim} -DatasetMulti <- function(Weight, Dose, N = 20, Tau = 24){ - #set.seed(20140523+1) - MVN <- rmvn(N, CaffMu, CaffSigma); - MVNdata <- data.frame(MVN, stringsAsFactors = FALSE) %>% - select(eta1 = X1, eta2 = X2, eta3 = X3) %>% - mutate(CL = 0.09792 * Weight * exp(eta1), # L/hr - V = 0.7219 * Weight * exp(eta2), # L, TVV =THETA[2] * (1 + ABST*THETA[7]) [1] 0.7218775 - Ka = 4.268 * exp(eta3), # /hr - Ke = CL / V, - Half_life = 0.693 / Ke, - Tmax = (log(Ka) - log(Ke)) / (Ka - Ke), - Cmax = Dose / V * Ka / (Ka - Ke) * (exp(-Ke * Tmax) - exp(-Ka * Tmax)), - AUC = Dose / CL - ) %>% - mutate(AI = 1/(1-exp(-1*Ke*Tau)), - Aavss = 1.44 * Dose * Half_life / Tau, - Cavss = Dose / (CL * Tau), - Cminss = Dose * exp(-Ke * Tau) / (V * (1 - exp(-Ke * Tau))), - Cmaxss = Dose / (V * (1 - exp(-Ke * Tau)))) %>% - select(TmaxS = Tmax, CmaxS = Cmax, AUCS = AUC, AI, Aavss, Cavss, Cmaxss, Cminss) - return(MVNdata) +caffDatasetMulti <- function(Weight, Dose, N = 20, Tau = 24){ + #set.seed(20140523+1) + MVN <- mgcv::rmvn(N, CaffMu, CaffSigma) + MVNdata <- data.frame(MVN, stringsAsFactors = FALSE) %>% + select(eta1 = X1, eta2 = X2, eta3 = X3) %>% + mutate(CL = 0.09792 * Weight * exp(eta1), # L/hr + V = 0.7219 * Weight * exp(eta2), # L, TVV =THETA[2] * (1 + ABST*THETA[7]) [1] 0.7218775 + Ka = 4.268 * exp(eta3), # /hr + Ke = CL / V, + Half_life = 0.693 / Ke, + Tmax = (log(Ka) - log(Ke)) / (Ka - Ke), + Cmax = Dose / V * Ka / (Ka - Ke) * (exp(-Ke * Tmax) - exp(-Ka * Tmax)), + AUC = Dose / CL + ) %>% + mutate(AI = 1/(1-exp(-1*Ke*Tau)), + Aavss = 1.44 * Dose * Half_life / Tau, + Cavss = Dose / (CL * Tau), + Cminss = Dose * exp(-Ke * Tau) / (V * (1 - exp(-Ke * Tau))), + Cmaxss = Dose / (V * (1 - exp(-Ke * Tau)))) %>% + select(TmaxS = Tmax, CmaxS = Cmax, AUCS = AUC, AI, Aavss, Cavss, Cmaxss, Cminss) + return(MVNdata) } - diff --git a/R/Plot.R b/R/Plot.R index 865d452..5382b56 100644 --- a/R/Plot.R +++ b/R/Plot.R @@ -7,25 +7,25 @@ #' @return The concentration-time curve #' @export #' @examples -#' Plot(ConcTime(Weight = 20, Dose = 200, N = 20)) -#' @seealso \url{http://asancpt.github.io/CaffeineEdison} +#' caffPlot(caffConcTime(Weight = 20, Dose = 200, N = 20)) #' @import dplyr #' @import ggplot2 +#' @seealso \url{https://asancpt.github.io/caffsim} -Plot <- function(ConcTime, log = FALSE){ - p <- ggplot(ConcTime, aes(x=Time, y=Conc)) + - xlab("Time (hour)") + ylab("Concentration (mg/L)") + - scale_x_continuous(breaks = seq(from = 0, to = 24, by = 4)) + - #scale_color_gradient2() + - #scale_colour_gradient(low="navy", high="red", space="Lab") + - geom_line(aes(group = Subject, colour = Conc)) + - stat_summary(fun.y = "mean", colour = "#F0E442", size = 1, geom = "line") + - geom_hline(yintercept = 80, colour="red") + - geom_hline(yintercept = 40, colour="blue") + - geom_hline(yintercept = 10, colour="green") + theme_linedraw() - - if (log == TRUE) p <- p + scale_y_log10() #limits = c(0.1, max(80, ggConc$Conc)))) - return(p) +caffPlot <- function(caffConcTime, log = FALSE){ + p <- ggplot(caffConcTime, aes(x=Time, y=Conc)) + + xlab("Time (hour)") + ylab("Concentration (mg/L)") + + scale_x_continuous(breaks = seq(from = 0, to = 24, by = 4)) + + #scale_color_gradient2() + + #scale_colour_gradient(low="navy", high="red", space="Lab") + + geom_line(aes(group = Subject, colour = Conc)) + + stat_summary(fun.y = "mean", colour = "#F0E442", size = 1, geom = "line") + + geom_hline(yintercept = 80, colour="red") + + geom_hline(yintercept = 40, colour="blue") + + geom_hline(yintercept = 10, colour="green") + theme_linedraw() + + if (log == TRUE) p <- p + scale_y_log10() #limits = c(0.1, max(80, ggConc$Conc)))) + return(p) } #' Create concentration-time curve after multiple doses of caffeine @@ -37,22 +37,22 @@ Plot <- function(ConcTime, log = FALSE){ #' @return The concentration-time curve #' @export #' @examples -#' PlotMulti(ConcTimeMulti(Weight = 20, Dose = 200, N = 20, Tau = 8, Repeat = 4)) -#' @seealso \url{http://asancpt.github.io/CaffeineEdison} +#' caffPlotMulti(ConcTimeMulti(Weight = 20, Dose = 200, N = 20, Tau = 8, Repeat = 4)) #' @import dplyr #' @import ggplot2 +#' @seealso \url{https://asancpt.github.io/caffsim} -PlotMulti <- function(ConcTimeMulti, log = FALSE){ - p <- ggplot(ConcTimeMulti, aes(x=Time, y=Conc)) + #, group=Subject, colour = Conc)) + #Subject)) + - xlab("Time (hour)") + ylab("Concentration (mg/L)") + - scale_x_continuous(breaks = seq(0, 96, 12)) + - #scale_colour_gradient(low="navy", high="red", space="Lab") + - geom_line(aes(group = Subject, colour = Conc)) + - stat_summary(fun.y = "mean", colour = "#F0E442", size = 1, geom = "line") + - geom_hline(yintercept = 80, colour="red") + - geom_hline(yintercept = 40, colour="blue") + - geom_hline(yintercept = 10, colour="green") + theme_linedraw() - - if (log == TRUE) p <- p + scale_y_log10() #limits = c(0.1, max(80, ggConc$Conc)))) - return(p) +caffPlotMulti <- function(caffConcTimeMulti, log = FALSE){ + p <- ggplot(caffConcTimeMulti, aes(x=Time, y=Conc)) + #, group=Subject, colour = Conc)) + #Subject)) + + xlab("Time (hour)") + ylab("Concentration (mg/L)") + + scale_x_continuous(breaks = seq(0, 96, 12)) + + #scale_colour_gradient(low="navy", high="red", space="Lab") + + geom_line(aes(group = Subject, colour = Conc)) + + stat_summary(fun.y = "mean", colour = "#F0E442", size = 1, geom = "line") + + geom_hline(yintercept = 80, colour="red") + + geom_hline(yintercept = 40, colour="blue") + + geom_hline(yintercept = 10, colour="green") + theme_linedraw() + + if (log == TRUE) p <- p + scale_y_log10() #limits = c(0.1, max(80, ggConc$Conc)))) + return(p) } diff --git a/R/data.R b/R/data.R index 8368c5a..4ccd2f5 100644 --- a/R/data.R +++ b/R/data.R @@ -7,6 +7,6 @@ #' \item{Parameters}{Abbreviated pharmacokinetic parameters} #' \item{Parameter}{Pharmacokinetic parameters in full name} #' } -#' @source \url{http://asancpt.github.io/CaffeineEdison} +#' @seealso \url{https://asancpt.github.io/caffsim} "UnitTable" \ No newline at end of file diff --git a/R/sysdata.rda b/R/sysdata.rda index f17b20e..bf18a66 100644 Binary files a/R/sysdata.rda and b/R/sysdata.rda differ diff --git a/README.Rmd b/README.Rmd index 464a90f..d520409 100644 --- a/README.Rmd +++ b/README.Rmd @@ -9,7 +9,7 @@ editor_options: ```{r include = FALSE} knitr::opts_chunk$set(collapse = TRUE, #comment = "#>", - fig.width = 7, fig.height = 7, fig.align = "center") + fig.width = 7, fig.height = 7, fig.align = "center") ``` # R package: caffsim @@ -21,13 +21,13 @@ knitr::opts_chunk$set(collapse = TRUE, #comment = "#>", - Reproducible research is expected. ```{r setup, include = FALSE} -library(caffsim) + knitr::opts_chunk$set(fig.width=8, fig.height=4, dev = 'png', dpi = 150, - #out.width = '5%', out.height = '5%',# For word dpi = 72 - #out.extra ='WIDTH="10%"', - fig.path='Figures/', echo=TRUE, warning=FALSE, message=FALSE, - cache=TRUE, - results = 'asis') + #out.width = '5%', out.height = '5%',# For word dpi = 72 + #out.extra ='WIDTH="10%"', + fig.path='assets/figures/', echo=TRUE, warning=FALSE, message=FALSE, + cache=TRUE, + results = 'asis') ``` ## Installation @@ -37,10 +37,10 @@ install.pacakges("devtools") devtools::install_github("asancpt/caffsim") # Simply create single dose dataset -caffsim::Dataset(Weight = 20, Dose = 200, N = 20) +caffsim::caffDataset(Weight = 20, Dose = 200, N = 20) # Simply create multiple dose dataset -caffsim::DatasetMulti(Weight = 20, Dose = 200, N = 20, Tau = 12) +caffsim::caffDatasetMulti(Weight = 20, Dose = 200, N = 20, Tau = 12) ``` ## Single dose @@ -48,21 +48,22 @@ caffsim::DatasetMulti(Weight = 20, Dose = 200, N = 20, Tau = 12) ### Create a PK dataset for caffeine single dose ```{r} -MyDataset <- caffsim::Dataset(Weight = 20, Dose = 200, N = 20) +library(caffsim) +MyDataset <- caffDataset(Weight = 20, Dose = 200, N = 20) knitr::kable(head(MyDataset), format = "markdown") ``` ### Create a dataset for concentration-time curve ```{r} -MyConcTime <- ConcTime(Weight = 20, Dose = 200, N = 20) +MyConcTime <- caffConcTime(Weight = 20, Dose = 200, N = 20) knitr::kable(head(MyConcTime), format = "markdown") ``` ### Create a concentration-time curve ```{r MyPlotMyConcTime} -Plot(MyConcTime) +caffPlot(MyConcTime) ``` ### Create plots for publication (according to the amount of caffeine) @@ -74,16 +75,16 @@ Plot(MyConcTime) library(cowplot) MyPlotPub <- lapply( - c(seq(100, 800, by = 100)), - function(x) PlotMulti(ConcTime(20, x, 20)) + - theme(legend.position="none") + - labs(title = paste0("Single Dose ", x, "mg"))) - -plot(plot_grid(MyPlotPub[[1]], MyPlotPub[[2]], - MyPlotPub[[3]], MyPlotPub[[4]], - MyPlotPub[[5]], MyPlotPub[[6]], - MyPlotPub[[7]], MyPlotPub[[8]], - labels=LETTERS[1:8], ncol = 2, nrow = 4)) + c(seq(100, 800, by = 100)), + function(x) caffPlotMulti(caffConcTime(20, x, 20)) + + theme(legend.position="none") + + labs(title = paste0("Single Dose ", x, "mg"))) + +plot_grid(MyPlotPub[[1]], MyPlotPub[[2]], + MyPlotPub[[3]], MyPlotPub[[4]], + MyPlotPub[[5]], MyPlotPub[[6]], + MyPlotPub[[7]], MyPlotPub[[8]], + labels=LETTERS[1:8], ncol = 2, nrow = 4) ``` ## Multiple dose @@ -91,21 +92,21 @@ plot(plot_grid(MyPlotPub[[1]], MyPlotPub[[2]], ### Create a PK dataset for caffeine multiple doses ```{r} -MyDatasetMulti <- DatasetMulti(Weight = 20, Dose = 200, N = 20, Tau = 12) +MyDatasetMulti <- caffDatasetMulti(Weight = 20, Dose = 200, N = 20, Tau = 12) knitr::kable(head(MyDatasetMulti), format = "markdown") ``` ### Create a dataset for concentration-time curve ```{r} -MyConcTimeMulti <- ConcTimeMulti(Weight = 20, Dose = 200, N = 20, Tau = 12, Repeat = 10) +MyConcTimeMulti <- caffConcTimeMulti(Weight = 20, Dose = 200, N = 20, Tau = 12, Repeat = 10) knitr::kable(head(MyConcTimeMulti), format = "markdown") ``` ### Create a concentration-time curve ```{r MyPlotMultiMyConcTimeMulti} -PlotMulti(MyConcTimeMulti) +caffPlotMulti(MyConcTimeMulti) ``` ### Create plots for publication (according to dosing interval) @@ -117,14 +118,14 @@ PlotMulti(MyConcTimeMulti) library(cowplot) MyPlotMultiPub <- lapply( - c(seq(4, 32, by = 4)), - function(x) PlotMulti(ConcTimeMulti(20, 250, 20, x, 15)) + - theme(legend.position="none") + - labs(title = paste0("q", x, "hr" ))) - -plot(plot_grid(MyPlotMultiPub[[1]], MyPlotMultiPub[[2]], - MyPlotMultiPub[[3]], MyPlotMultiPub[[4]], - MyPlotMultiPub[[5]], MyPlotMultiPub[[6]], - MyPlotMultiPub[[7]], MyPlotMultiPub[[8]], - labels=LETTERS[1:8], ncol = 2, nrow = 4)) + c(seq(4, 32, by = 4)), + function(x) caffPlotMulti(caffConcTimeMulti(20, 250, 20, x, 15)) + + theme(legend.position="none") + + labs(title = paste0("q", x, "hr" ))) + +plot_grid(MyPlotMultiPub[[1]], MyPlotMultiPub[[2]], + MyPlotMultiPub[[3]], MyPlotMultiPub[[4]], + MyPlotMultiPub[[5]], MyPlotMultiPub[[6]], + MyPlotMultiPub[[7]], MyPlotMultiPub[[8]], + labels=LETTERS[1:8], ncol = 2, nrow = 4) ``` diff --git a/README.html b/README.html index a2ab774..3ee8480 100644 --- a/README.html +++ b/README.html @@ -135,16 +135,17 @@

Installation

devtools::install_github("asancpt/caffsim") # Simply create single dose dataset -caffsim::Dataset(Weight = 20, Dose = 200, N = 20) +caffsim::caffDataset(Weight = 20, Dose = 200, N = 20) # Simply create multiple dose dataset -caffsim::DatasetMulti(Weight = 20, Dose = 200, N = 20, Tau = 12) +caffsim::caffDatasetMulti(Weight = 20, Dose = 200, N = 20, Tau = 12)

Single dose

Create a PK dataset for caffeine single dose

-
MyDataset <- caffsim::Dataset(Weight = 20, Dose = 200, N = 20)
+
library(caffsim)
+MyDataset <- caffDataset(Weight = 20, Dose = 200, N = 20)
 knitr::kable(head(MyDataset), format = "markdown")
@@ -161,71 +162,71 @@

Create a PK dataset for caffeine single dose

- - - - - - - - + + + + + + + + - - - - - - - - + + + + + + + + - - - - - - - - + + + + + + + + - - - - - - - - + + + + + + + + - - - - - - - - + + + + + + + + - - - - - - - - + + + + + + + +
0.810715911.825709103.744465.4879521.92781415.266594.54665710.12627660.750695010.90455699.339495.7687552.01329816.759345.1181240.1201299
0.943756810.87149371.347133.8348972.80319615.512223.23876310.18070890.97562809.53519478.965505.0152622.53275118.329603.4302600.1381782
1.063219611.995621191.4341110.2955381.04474615.521243.88067680.06731070.886980714.09155581.221703.3190752.46239611.793473.3315900.2087931
1.49979049.44854178.293344.5755262.55449616.866031.80292810.15145800.645847012.05857095.708975.0322682.08966815.174275.9753850.1377113
2.766940912.938048148.358865.6645661.34808311.019200.80182130.12233950.24660918.60729272.154055.6358302.77184722.5420820.9594150.1229632
0.70048637.44773567.333725.7588122.97028024.682955.60343820.12033730.274734412.55845767.175183.5112092.97729015.0849816.2526690.1973679

Create a dataset for concentration-time curve

-
MyConcTime <- ConcTime(Weight = 20, Dose = 200, N = 20)
+
MyConcTime <- caffConcTime(Weight = 20, Dose = 200, N = 20)
 knitr::kable(head(MyConcTime), format = "markdown")
@@ -244,35 +245,35 @@

Create a dataset for concentration-time curve

- + - + - + - + - +
1 0.15.5682535.117929
1 0.28.3778977.721610
1 0.39.7523209.025087
1 0.410.3807209.656359
1 0.510.6220089.940279

Create a concentration-time curve

-
Plot(MyConcTime)
-

+
caffPlot(MyConcTime)
+

Create plots for publication (according to the amount of caffeine)

@@ -283,24 +284,24 @@

Create plots for publication (according to the amount of caffeine)

library(cowplot) MyPlotPub <- lapply( - c(seq(100, 800, by = 100)), - function(x) PlotMulti(ConcTime(20, x, 20)) + - theme(legend.position="none") + - labs(title = paste0("Single Dose ", x, "mg"))) - -plot(plot_grid(MyPlotPub[[1]], MyPlotPub[[2]], - MyPlotPub[[3]], MyPlotPub[[4]], - MyPlotPub[[5]], MyPlotPub[[6]], - MyPlotPub[[7]], MyPlotPub[[8]], - labels=LETTERS[1:8], ncol = 2, nrow = 4))
-

+ c(seq(100, 800, by = 100)), + function(x) caffPlotMulti(caffConcTime(20, x, 20)) + + theme(legend.position="none") + + labs(title = paste0("Single Dose ", x, "mg"))) + +plot_grid(MyPlotPub[[1]], MyPlotPub[[2]], + MyPlotPub[[3]], MyPlotPub[[4]], + MyPlotPub[[5]], MyPlotPub[[6]], + MyPlotPub[[7]], MyPlotPub[[8]], + labels=LETTERS[1:8], ncol = 2, nrow = 4)
+

Multiple dose

Create a PK dataset for caffeine multiple doses

-
MyDatasetMulti <- DatasetMulti(Weight = 20, Dose = 200, N = 20, Tau = 12)
+
MyDatasetMulti <- caffDatasetMulti(Weight = 20, Dose = 200, N = 20, Tau = 12)
 knitr::kable(head(MyDatasetMulti), format = "markdown")
@@ -317,71 +318,71 @@

Create a PK dataset for caffeine multiple doses

- - - - - - - - + + + + + + + + - - - - - - - - + + + + + + + + - - - - - - - - + + + + + + + + - - - - - - - - + + + + + + + + - - - - - - - - + + + + + + + + - - - - - - - - + + + + + + + +
1.055587913.14951176.401731.606035204.7885714.70014423.008948.68239450.923610012.730981122.836451.334606144.2667710.23637118.899864.7384847
2.028251411.49687125.476531.331292143.4921910.45637819.362084.81825402.251575612.207227158.306921.464930173.9027413.19224322.179667.0392348
1.212883712.64804119.422261.296532135.284339.95185519.035564.35365520.217843112.46911483.513131.185915107.709686.95942715.293192.3974994
0.896063815.90481153.631801.337576144.9596812.80265023.577445.95044680.62287407.48780643.613231.10845085.863703.6344369.364170.9161845
0.794228810.96006106.004481.346524147.041768.83370616.145164.15491254.00273039.990159146.936291.413289162.3256812.24469121.277336.2221419
1.207241511.3863363.237081.05886869.068295.26975716.124240.89642750.74948839.44818855.460291.10305884.193264.62169112.085031.1291008

Create a dataset for concentration-time curve

-
MyConcTimeMulti <- ConcTimeMulti(Weight = 20, Dose = 200, N = 20, Tau = 12, Repeat = 10)
+
MyConcTimeMulti <- caffConcTimeMulti(Weight = 20, Dose = 200, N = 20, Tau = 12, Repeat = 10)
 knitr::kable(head(MyConcTimeMulti), format = "markdown")
@@ -400,35 +401,35 @@

Create a dataset for concentration-time curve

- + - + - + - + - +
1 0.210.5030412.974553
1 0.410.1445045.015058
1 0.69.7662576.390925
1 0.89.4020127.294470
1 1.09.0513527.862957

Create a concentration-time curve

-
PlotMulti(MyConcTimeMulti)
-

+
caffPlotMulti(MyConcTimeMulti)
+

Create plots for publication (according to dosing interval)

@@ -439,17 +440,17 @@

Create plots for publication (according to dosing interval)

library(cowplot) MyPlotMultiPub <- lapply( - c(seq(4, 32, by = 4)), - function(x) PlotMulti(ConcTimeMulti(20, 250, 20, x, 15)) + - theme(legend.position="none") + - labs(title = paste0("q", x, "hr" ))) - -plot(plot_grid(MyPlotMultiPub[[1]], MyPlotMultiPub[[2]], - MyPlotMultiPub[[3]], MyPlotMultiPub[[4]], - MyPlotMultiPub[[5]], MyPlotMultiPub[[6]], - MyPlotMultiPub[[7]], MyPlotMultiPub[[8]], - labels=LETTERS[1:8], ncol = 2, nrow = 4))
-

+ c(seq(4, 32, by = 4)), + function(x) caffPlotMulti(caffConcTimeMulti(20, 250, 20, x, 15)) + + theme(legend.position="none") + + labs(title = paste0("q", x, "hr" ))) + +plot_grid(MyPlotMultiPub[[1]], MyPlotMultiPub[[2]], + MyPlotMultiPub[[3]], MyPlotMultiPub[[4]], + MyPlotMultiPub[[5]], MyPlotMultiPub[[6]], + MyPlotMultiPub[[7]], MyPlotMultiPub[[8]], + labels=LETTERS[1:8], ncol = 2, nrow = 4)
+

@@ -477,7 +478,7 @@

Create plots for publication (according to dosing interval)

(function () { var script = document.createElement("script"); script.type = "text/javascript"; - script.src = "https://cdn.mathjax.org/mathjax/latest/MathJax.js?config=TeX-AMS-MML_HTMLorMML"; + script.src = "https://mathjax.rstudio.com/latest/MathJax.js?config=TeX-AMS-MML_HTMLorMML"; document.getElementsByTagName("head")[0].appendChild(script); })(); diff --git a/README.md b/README.md index c64c5c4..f22875a 100644 --- a/README.md +++ b/README.md @@ -19,10 +19,10 @@ install.pacakges("devtools") devtools::install_github("asancpt/caffsim") # Simply create single dose dataset -caffsim::Dataset(Weight = 20, Dose = 200, N = 20) +caffsim::caffDataset(Weight = 20, Dose = 200, N = 20) # Simply create multiple dose dataset -caffsim::DatasetMulti(Weight = 20, Dose = 200, N = 20, Tau = 12) +caffsim::caffDatasetMulti(Weight = 20, Dose = 200, N = 20, Tau = 12) ``` ## Single dose @@ -31,48 +31,49 @@ caffsim::DatasetMulti(Weight = 20, Dose = 200, N = 20, Tau = 12) ```r -MyDataset <- caffsim::Dataset(Weight = 20, Dose = 200, N = 20) +library(caffsim) +MyDataset <- caffDataset(Weight = 20, Dose = 200, N = 20) knitr::kable(head(MyDataset), format = "markdown") ``` -| Tmax| Cmax| AUC| Half_life| CL| V| Ka| Ke| -|---------:|---------:|---------:|---------:|--------:|--------:|---------:|---------:| -| 0.8107159| 11.825709| 103.74446| 5.487952| 1.927814| 15.26659| 4.5466571| 0.1262766| -| 0.9437568| 10.871493| 71.34713| 3.834897| 2.803196| 15.51222| 3.2387631| 0.1807089| -| 1.0632196| 11.995621| 191.43411| 10.295538| 1.044746| 15.52124| 3.8806768| 0.0673107| -| 1.4997904| 9.448541| 78.29334| 4.575526| 2.554496| 16.86603| 1.8029281| 0.1514580| -| 2.7669409| 12.938048| 148.35886| 5.664566| 1.348083| 11.01920| 0.8018213| 0.1223395| -| 0.7004863| 7.447735| 67.33372| 5.758812| 2.970280| 24.68295| 5.6034382| 0.1203373| +| Tmax| Cmax| AUC| Half_life| CL| V| Ka| Ke| +|---------:|---------:|--------:|---------:|--------:|--------:|---------:|---------:| +| 0.7506950| 10.904556| 99.33949| 5.768755| 2.013298| 16.75934| 5.118124| 0.1201299| +| 0.9756280| 9.535194| 78.96550| 5.015262| 2.532751| 18.32960| 3.430260| 0.1381782| +| 0.8869807| 14.091555| 81.22170| 3.319075| 2.462396| 11.79347| 3.331590| 0.2087931| +| 0.6458470| 12.058570| 95.70897| 5.032268| 2.089668| 15.17427| 5.975385| 0.1377113| +| 0.2466091| 8.607292| 72.15405| 5.635830| 2.771847| 22.54208| 20.959415| 0.1229632| +| 0.2747344| 12.558457| 67.17518| 3.511209| 2.977290| 15.08498| 16.252669| 0.1973679| ### Create a dataset for concentration-time curve ```r -MyConcTime <- ConcTime(Weight = 20, Dose = 200, N = 20) +MyConcTime <- caffConcTime(Weight = 20, Dose = 200, N = 20) knitr::kable(head(MyConcTime), format = "markdown") ``` -| Subject| Time| Conc| -|-------:|----:|---------:| -| 1| 0.0| 0.000000| -| 1| 0.1| 5.568253| -| 1| 0.2| 8.377897| -| 1| 0.3| 9.752320| -| 1| 0.4| 10.380720| -| 1| 0.5| 10.622008| +| Subject| Time| Conc| +|-------:|----:|--------:| +| 1| 0.0| 0.000000| +| 1| 0.1| 5.117929| +| 1| 0.2| 7.721610| +| 1| 0.3| 9.025087| +| 1| 0.4| 9.656359| +| 1| 0.5| 9.940279| ### Create a concentration-time curve ```r -Plot(MyConcTime) +caffPlot(MyConcTime) ``` - + ### Create plots for publication (according to the amount of caffeine) @@ -84,19 +85,19 @@ Plot(MyConcTime) library(cowplot) MyPlotPub <- lapply( - c(seq(100, 800, by = 100)), - function(x) PlotMulti(ConcTime(20, x, 20)) + - theme(legend.position="none") + - labs(title = paste0("Single Dose ", x, "mg"))) - -plot(plot_grid(MyPlotPub[[1]], MyPlotPub[[2]], - MyPlotPub[[3]], MyPlotPub[[4]], - MyPlotPub[[5]], MyPlotPub[[6]], - MyPlotPub[[7]], MyPlotPub[[8]], - labels=LETTERS[1:8], ncol = 2, nrow = 4)) + c(seq(100, 800, by = 100)), + function(x) caffPlotMulti(caffConcTime(20, x, 20)) + + theme(legend.position="none") + + labs(title = paste0("Single Dose ", x, "mg"))) + +plot_grid(MyPlotPub[[1]], MyPlotPub[[2]], + MyPlotPub[[3]], MyPlotPub[[4]], + MyPlotPub[[5]], MyPlotPub[[6]], + MyPlotPub[[7]], MyPlotPub[[8]], + labels=LETTERS[1:8], ncol = 2, nrow = 4) ``` - + ## Multiple dose @@ -104,48 +105,48 @@ plot(plot_grid(MyPlotPub[[1]], MyPlotPub[[2]], ```r -MyDatasetMulti <- DatasetMulti(Weight = 20, Dose = 200, N = 20, Tau = 12) +MyDatasetMulti <- caffDatasetMulti(Weight = 20, Dose = 200, N = 20, Tau = 12) knitr::kable(head(MyDatasetMulti), format = "markdown") ``` -| TmaxS| CmaxS| AUCS| AI| Aavss| Cavss| Cmaxss| Cminss| -|---------:|--------:|---------:|--------:|---------:|---------:|--------:|---------:| -| 1.0555879| 13.14951| 176.40173| 1.606035| 204.78857| 14.700144| 23.00894| 8.6823945| -| 2.0282514| 11.49687| 125.47653| 1.331292| 143.49219| 10.456378| 19.36208| 4.8182540| -| 1.2128837| 12.64804| 119.42226| 1.296532| 135.28433| 9.951855| 19.03556| 4.3536552| -| 0.8960638| 15.90481| 153.63180| 1.337576| 144.95968| 12.802650| 23.57744| 5.9504468| -| 0.7942288| 10.96006| 106.00448| 1.346524| 147.04176| 8.833706| 16.14516| 4.1549125| -| 1.2072415| 11.38633| 63.23708| 1.058868| 69.06829| 5.269757| 16.12424| 0.8964275| +| TmaxS| CmaxS| AUCS| AI| Aavss| Cavss| Cmaxss| Cminss| +|---------:|---------:|---------:|--------:|---------:|---------:|--------:|---------:| +| 0.9236100| 12.730981| 122.83645| 1.334606| 144.26677| 10.236371| 18.89986| 4.7384847| +| 2.2515756| 12.207227| 158.30692| 1.464930| 173.90274| 13.192243| 22.17966| 7.0392348| +| 0.2178431| 12.469114| 83.51313| 1.185915| 107.70968| 6.959427| 15.29319| 2.3974994| +| 0.6228740| 7.487806| 43.61323| 1.108450| 85.86370| 3.634436| 9.36417| 0.9161845| +| 4.0027303| 9.990159| 146.93629| 1.413289| 162.32568| 12.244691| 21.27733| 6.2221419| +| 0.7494883| 9.448188| 55.46029| 1.103058| 84.19326| 4.621691| 12.08503| 1.1291008| ### Create a dataset for concentration-time curve ```r -MyConcTimeMulti <- ConcTimeMulti(Weight = 20, Dose = 200, N = 20, Tau = 12, Repeat = 10) +MyConcTimeMulti <- caffConcTimeMulti(Weight = 20, Dose = 200, N = 20, Tau = 12, Repeat = 10) knitr::kable(head(MyConcTimeMulti), format = "markdown") ``` -| Subject| Time| Conc| -|-------:|----:|---------:| -| 1| 0.0| 0.000000| -| 1| 0.2| 10.503041| -| 1| 0.4| 10.144504| -| 1| 0.6| 9.766257| -| 1| 0.8| 9.402012| -| 1| 1.0| 9.051352| +| Subject| Time| Conc| +|-------:|----:|--------:| +| 1| 0.0| 0.000000| +| 1| 0.2| 2.974553| +| 1| 0.4| 5.015058| +| 1| 0.6| 6.390925| +| 1| 0.8| 7.294470| +| 1| 1.0| 7.862957| ### Create a concentration-time curve ```r -PlotMulti(MyConcTimeMulti) +caffPlotMulti(MyConcTimeMulti) ``` - + ### Create plots for publication (according to dosing interval) @@ -157,16 +158,16 @@ PlotMulti(MyConcTimeMulti) library(cowplot) MyPlotMultiPub <- lapply( - c(seq(4, 32, by = 4)), - function(x) PlotMulti(ConcTimeMulti(20, 250, 20, x, 15)) + - theme(legend.position="none") + - labs(title = paste0("q", x, "hr" ))) - -plot(plot_grid(MyPlotMultiPub[[1]], MyPlotMultiPub[[2]], - MyPlotMultiPub[[3]], MyPlotMultiPub[[4]], - MyPlotMultiPub[[5]], MyPlotMultiPub[[6]], - MyPlotMultiPub[[7]], MyPlotMultiPub[[8]], - labels=LETTERS[1:8], ncol = 2, nrow = 4)) + c(seq(4, 32, by = 4)), + function(x) caffPlotMulti(caffConcTimeMulti(20, 250, 20, x, 15)) + + theme(legend.position="none") + + labs(title = paste0("q", x, "hr" ))) + +plot_grid(MyPlotMultiPub[[1]], MyPlotMultiPub[[2]], + MyPlotMultiPub[[3]], MyPlotMultiPub[[4]], + MyPlotMultiPub[[5]], MyPlotMultiPub[[6]], + MyPlotMultiPub[[7]], MyPlotMultiPub[[8]], + labels=LETTERS[1:8], ncol = 2, nrow = 4) ``` - + diff --git a/_pkgdown.yml b/_pkgdown.yml deleted file mode 100644 index 8a4185e..0000000 --- a/_pkgdown.yml +++ /dev/null @@ -1,12 +0,0 @@ -template: - package: tidytemplate - -# params: -# bootswatch: flatly - -# navbar: -# left: -# - text: Intro -# href: articles/pkgdown.html -# - text: Reference -# href: reference/index.html diff --git a/assets/figures/MyPlotMultiMyConcTimeMulti-1.png b/assets/figures/MyPlotMultiMyConcTimeMulti-1.png new file mode 100644 index 0000000..e3923b9 Binary files /dev/null and b/assets/figures/MyPlotMultiMyConcTimeMulti-1.png differ diff --git a/assets/figures/MyPlotMultiPub-1.png b/assets/figures/MyPlotMultiPub-1.png new file mode 100644 index 0000000..239ded7 Binary files /dev/null and b/assets/figures/MyPlotMultiPub-1.png differ diff --git a/assets/figures/MyPlotMyConcTime-1.png b/assets/figures/MyPlotMyConcTime-1.png new file mode 100644 index 0000000..6ad5226 Binary files /dev/null and b/assets/figures/MyPlotMyConcTime-1.png differ diff --git a/assets/figures/MyPlotPub-1.png b/assets/figures/MyPlotPub-1.png new file mode 100644 index 0000000..910b34c Binary files /dev/null and b/assets/figures/MyPlotPub-1.png differ diff --git a/caffsim.pdf b/caffsim.pdf index ab87fa7..d7b743e 100644 Binary files a/caffsim.pdf and b/caffsim.pdf differ diff --git a/clean_site.sh b/clean_site.sh deleted file mode 100644 index 6d786b1..0000000 --- a/clean_site.sh +++ /dev/null @@ -1 +0,0 @@ -Rscript -e "pkgdown::clean_site()" diff --git a/data-raw/use_data.R b/data-raw/use_data.R index 794598b..4daacf1 100644 --- a/data-raw/use_data.R +++ b/data-raw/use_data.R @@ -34,6 +34,8 @@ Get_os <- function(){ tolower(os) } +# save ---- + devtools::use_data(CaffSigma, CaffMu, Seed, @@ -41,4 +43,3 @@ devtools::use_data(CaffSigma, Get_os, UnitTable, internal = TRUE, overwrite = TRUE) - diff --git a/docs/Figures/MyPlotMultiMyConcTimeMulti-1.png b/docs/Figures/MyPlotMultiMyConcTimeMulti-1.png deleted file mode 100644 index ce39bd3..0000000 Binary files a/docs/Figures/MyPlotMultiMyConcTimeMulti-1.png and /dev/null differ diff --git a/docs/Figures/MyPlotMultiPub-1.png b/docs/Figures/MyPlotMultiPub-1.png deleted file mode 100644 index a5b5d53..0000000 Binary files a/docs/Figures/MyPlotMultiPub-1.png and /dev/null differ diff --git a/docs/Figures/MyPlotMyConcTime-1.png b/docs/Figures/MyPlotMyConcTime-1.png deleted file mode 100644 index 67397e3..0000000 Binary files a/docs/Figures/MyPlotMyConcTime-1.png and /dev/null differ diff --git a/docs/Figures/MyPlotPub-1.png b/docs/Figures/MyPlotPub-1.png deleted file mode 100644 index 3088ec6..0000000 Binary files a/docs/Figures/MyPlotPub-1.png and /dev/null differ diff --git a/docs/LICENSE b/docs/LICENSE.html similarity index 83% rename from docs/LICENSE rename to docs/LICENSE.html index 9cecc1d..eb64db3 100644 --- a/docs/LICENSE +++ b/docs/LICENSE.html @@ -1,7 +1,92 @@ - GNU GENERAL PUBLIC LICENSE + + + + + + + + +License • caffsim + + + + + + + + + + + + + + + + + + + + + + + + + + + +
+
+ + + +
+ +
+
+ + +
                    GNU GENERAL PUBLIC LICENSE
                        Version 3, 29 June 2007
 
- Copyright (C) 2007 Free Software Foundation, Inc. 
+ Copyright (C) 2007 Free Software Foundation, Inc. <http://fsf.org/>
  Everyone is permitted to copy and distribute verbatim copies
  of this license document, but changing it is not allowed.
 
@@ -72,35 +157,35 @@
 
   0. Definitions.
 
-  "This License" refers to version 3 of the GNU General Public License.
+  "This License" refers to version 3 of the GNU General Public License.
 
-  "Copyright" also means copyright-like laws that apply to other kinds of
+  "Copyright" also means copyright-like laws that apply to other kinds of
 works, such as semiconductor masks.
 
-  "The Program" refers to any copyrightable work licensed under this
-License.  Each licensee is addressed as "you".  "Licensees" and
-"recipients" may be individuals or organizations.
+  "The Program" refers to any copyrightable work licensed under this
+License.  Each licensee is addressed as "you".  "Licensees" and
+"recipients" may be individuals or organizations.
 
-  To "modify" a work means to copy from or adapt all or part of the work
+  To "modify" a work means to copy from or adapt all or part of the work
 in a fashion requiring copyright permission, other than the making of an
-exact copy.  The resulting work is called a "modified version" of the
-earlier work or a work "based on" the earlier work.
+exact copy.  The resulting work is called a "modified version" of the
+earlier work or a work "based on" the earlier work.
 
-  A "covered work" means either the unmodified Program or a work based
+  A "covered work" means either the unmodified Program or a work based
 on the Program.
 
-  To "propagate" a work means to do anything with it that, without
+  To "propagate" a work means to do anything with it that, without
 permission, would make you directly or secondarily liable for
 infringement under applicable copyright law, except executing it on a
 computer or modifying a private copy.  Propagation includes copying,
 distribution (with or without modification), making available to the
 public, and in some countries other activities as well.
 
-  To "convey" a work means any kind of propagation that enables other
+  To "convey" a work means any kind of propagation that enables other
 parties to make or receive copies.  Mere interaction with a user through
 a computer network, with no transfer of a copy, is not conveying.
 
-  An interactive user interface displays "Appropriate Legal Notices"
+  An interactive user interface displays "Appropriate Legal Notices"
 to the extent that it includes a convenient and prominently visible
 feature that (1) displays an appropriate copyright notice, and (2)
 tells the user that there is no warranty for the work (except to the
@@ -111,27 +196,27 @@
 
   1. Source Code.
 
-  The "source code" for a work means the preferred form of the work
-for making modifications to it.  "Object code" means any non-source
+  The "source code" for a work means the preferred form of the work
+for making modifications to it.  "Object code" means any non-source
 form of a work.
 
-  A "Standard Interface" means an interface that either is an official
+  A "Standard Interface" means an interface that either is an official
 standard defined by a recognized standards body, or, in the case of
 interfaces specified for a particular programming language, one that
 is widely used among developers working in that language.
 
-  The "System Libraries" of an executable work include anything, other
+  The "System Libraries" of an executable work include anything, other
 than the work as a whole, that (a) is included in the normal form of
 packaging a Major Component, but which is not part of that Major
 Component, and (b) serves only to enable use of the work with that
 Major Component, or to implement a Standard Interface for which an
 implementation is available to the public in source code form.  A
-"Major Component", in this context, means a major essential component
+"Major Component", in this context, means a major essential component
 (kernel, window system, and so on) of the specific operating system
 (if any) on which the executable work runs, or a compiler used to
 produce the work, or an object code interpreter used to run it.
 
-  The "Corresponding Source" for a work in object code form means all
+  The "Corresponding Source" for a work in object code form means all
 the source code needed to generate, install, and (for an executable
 work) run the object code and to modify the work, including scripts to
 control those activities.  However, it does not include the work's
@@ -217,7 +302,7 @@
     b) The work must carry prominent notices stating that it is
     released under this License and any conditions added under section
     7.  This requirement modifies the requirement in section 4 to
-    "keep intact all notices".
+    "keep intact all notices".
 
     c) You must license the entire work, as a whole, under this
     License to anyone who comes into possession of a copy.  This
@@ -236,7 +321,7 @@
 works, which are not by their nature extensions of the covered work,
 and which are not combined with it such as to form a larger program,
 in or on a volume of a storage or distribution medium, is called an
-"aggregate" if the compilation and its resulting copyright are not
+"aggregate" if the compilation and its resulting copyright are not
 used to limit the access or legal rights of the compilation's users
 beyond what the individual works permit.  Inclusion of a covered work
 in an aggregate does not cause this License to apply to the other
@@ -294,12 +379,12 @@
 from the Corresponding Source as a System Library, need not be
 included in conveying the object code work.
 
-  A "User Product" is either (1) a "consumer product", which means any
+  A "User Product" is either (1) a "consumer product", which means any
 tangible personal property which is normally used for personal, family,
 or household purposes, or (2) anything designed or sold for incorporation
 into a dwelling.  In determining whether a product is a consumer product,
 doubtful cases shall be resolved in favor of coverage.  For a particular
-product received by a particular user, "normally used" refers to a
+product received by a particular user, "normally used" refers to a
 typical or common use of that class of product, regardless of the status
 of the particular user or of the way in which the particular user
 actually uses, or expects or is expected to use, the product.  A product
@@ -307,7 +392,7 @@
 commercial, industrial or non-consumer uses, unless such uses represent
 the only significant mode of use of the product.
 
-  "Installation Information" for a User Product means any methods,
+  "Installation Information" for a User Product means any methods,
 procedures, authorization keys, or other information required to install
 and execute modified versions of a covered work in that User Product from
 a modified version of its Corresponding Source.  The information must
@@ -342,7 +427,7 @@
 
   7. Additional Terms.
 
-  "Additional permissions" are terms that supplement the terms of this
+  "Additional permissions" are terms that supplement the terms of this
 License by making exceptions from one or more of its conditions.
 Additional permissions that are applicable to the entire Program shall
 be treated as though they were included in this License, to the extent
@@ -385,8 +470,8 @@
     any liability that these contractual assumptions directly impose on
     those licensors and authors.
 
-  All other non-permissive additional terms are considered "further
-restrictions" within the meaning of section 10.  If the Program as you
+  All other non-permissive additional terms are considered "further
+restrictions" within the meaning of section 10.  If the Program as you
 received it, or any part of it, contains a notice stating that it is
 governed by this License along with a term that is a further
 restriction, you may remove that term.  If a license document contains
@@ -450,7 +535,7 @@
 propagate that work, subject to this License.  You are not responsible
 for enforcing compliance by third parties with this License.
 
-  An "entity transaction" is a transaction transferring control of an
+  An "entity transaction" is a transaction transferring control of an
 organization, or substantially all assets of one, or subdividing an
 organization, or merging organizations.  If propagation of a covered
 work results from an entity transaction, each party to that
@@ -470,17 +555,17 @@
 
   11. Patents.
 
-  A "contributor" is a copyright holder who authorizes use under this
+  A "contributor" is a copyright holder who authorizes use under this
 License of the Program or a work on which the Program is based.  The
-work thus licensed is called the contributor's "contributor version".
+work thus licensed is called the contributor's "contributor version".
 
-  A contributor's "essential patent claims" are all patent claims
+  A contributor's "essential patent claims" are all patent claims
 owned or controlled by the contributor, whether already acquired or
 hereafter acquired, that would be infringed by some manner, permitted
 by this License, of making, using, or selling its contributor version,
 but do not include claims that would be infringed only as a
 consequence of further modification of the contributor version.  For
-purposes of this definition, "control" includes the right to grant
+purposes of this definition, "control" includes the right to grant
 patent sublicenses in a manner consistent with the requirements of
 this License.
 
@@ -489,10 +574,10 @@
 make, use, sell, offer for sale, import and otherwise run, modify and
 propagate the contents of its contributor version.
 
-  In the following three paragraphs, a "patent license" is any express
+  In the following three paragraphs, a "patent license" is any express
 agreement or commitment, however denominated, not to enforce a patent
 (such as an express permission to practice a patent or covenant not to
-sue for patent infringement).  To "grant" such a patent license to a
+sue for patent infringement).  To "grant" such a patent license to a
 party means to make such an agreement or commitment not to enforce a
 patent against the party.
 
@@ -504,7 +589,7 @@
 available, or (2) arrange to deprive yourself of the benefit of the
 patent license for this particular work, or (3) arrange, in a manner
 consistent with the requirements of this License, to extend the patent
-license to downstream recipients.  "Knowingly relying" means you have
+license to downstream recipients.  "Knowingly relying" means you have
 actual knowledge that, but for the patent license, your conveying the
 covered work in a country, or your recipient's use of the covered work
 in a country, would infringe one or more identifiable patents in that
@@ -518,7 +603,7 @@
 you grant is automatically extended to all recipients of the covered
 work and works based on it.
 
-  A patent license is "discriminatory" if it does not include within
+  A patent license is "discriminatory" if it does not include within
 the scope of its coverage, prohibits the exercise of, or is
 conditioned on the non-exercise of one or more of the rights that are
 specifically granted under this License.  You may not convey a covered
@@ -569,7 +654,7 @@
 
   Each version is given a distinguishing version number.  If the
 Program specifies that a certain numbered version of the GNU General
-Public License "or any later version" applies to it, you have the
+Public License "or any later version" applies to it, you have the
 option of following the terms and conditions either of that numbered
 version or of any later version published by the Free Software
 Foundation.  If the Program does not specify a version number of the
@@ -590,7 +675,7 @@
 
   THERE IS NO WARRANTY FOR THE PROGRAM, TO THE EXTENT PERMITTED BY
 APPLICABLE LAW.  EXCEPT WHEN OTHERWISE STATED IN WRITING THE COPYRIGHT
-HOLDERS AND/OR OTHER PARTIES PROVIDE THE PROGRAM "AS IS" WITHOUT WARRANTY
+HOLDERS AND/OR OTHER PARTIES PROVIDE THE PROGRAM "AS IS" WITHOUT WARRANTY
 OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING, BUT NOT LIMITED TO,
 THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR
 PURPOSE.  THE ENTIRE RISK AS TO THE QUALITY AND PERFORMANCE OF THE PROGRAM
@@ -629,7 +714,7 @@
   To do so, attach the following notices to the program.  It is safest
 to attach them to the start of each source file to most effectively
 state the exclusion of warranty; and each file should have at least
-the "copyright" line and a pointer to where the full notice is found.
+the "copyright" line and a pointer to where the full notice is found.
 
     {one line to give the program's name and a brief idea of what it does.}
     Copyright (C) {year}  {name of author}
@@ -645,7 +730,7 @@
     GNU General Public License for more details.
 
     You should have received a copy of the GNU General Public License
-    along with this program.  If not, see .
+    along with this program.  If not, see <http://www.gnu.org/licenses/>.
 
 Also add information on how to contact you by electronic and paper mail.
 
@@ -659,16 +744,37 @@
 
 The hypothetical commands `show w' and `show c' should show the appropriate
 parts of the General Public License.  Of course, your program's commands
-might be different; for a GUI interface, you would use an "about box".
+might be different; for a GUI interface, you would use an "about box".
 
   You should also get your employer (if you work as a programmer) or school,
-if any, to sign a "copyright disclaimer" for the program, if necessary.
+if any, to sign a "copyright disclaimer" for the program, if necessary.
 For more information on this, and how to apply and follow the GNU GPL, see
-.
+<http://www.gnu.org/licenses/>.
 
   The GNU General Public License does not permit incorporating your program
 into proprietary programs.  If your program is a subroutine library, you
 may consider it more useful to permit linking proprietary applications with
 the library.  If this is what you want to do, use the GNU Lesser General
 Public License instead of this License.  But first, please read
-.
+<http://www.gnu.org/philosophy/why-not-lgpl.html>.
+
+ +
+ +
+ + + +
+ + + diff --git a/docs/assets/figures/MyPlotMultiMyConcTimeMulti-1.png b/docs/assets/figures/MyPlotMultiMyConcTimeMulti-1.png new file mode 100644 index 0000000..10a2cb4 Binary files /dev/null and b/docs/assets/figures/MyPlotMultiMyConcTimeMulti-1.png differ diff --git a/docs/assets/figures/MyPlotMultiPub-1.png b/docs/assets/figures/MyPlotMultiPub-1.png new file mode 100644 index 0000000..5eece9b Binary files /dev/null and b/docs/assets/figures/MyPlotMultiPub-1.png differ diff --git a/docs/assets/figures/MyPlotMyConcTime-1.png b/docs/assets/figures/MyPlotMyConcTime-1.png new file mode 100644 index 0000000..5d3b43b Binary files /dev/null and b/docs/assets/figures/MyPlotMyConcTime-1.png differ diff --git a/docs/assets/figures/MyPlotPub-1.png b/docs/assets/figures/MyPlotPub-1.png new file mode 100644 index 0000000..dc54517 Binary files /dev/null and b/docs/assets/figures/MyPlotPub-1.png differ diff --git a/docs/authors.html b/docs/authors.html index c6b0325..1d61892 100644 --- a/docs/authors.html +++ b/docs/authors.html @@ -10,26 +10,30 @@ - - + + - + + - + + - + + + @@ -43,17 +47,22 @@ - - + caffsim diff --git a/docs/index.html b/docs/index.html index 6399198..9e7319b 100644 --- a/docs/index.html +++ b/docs/index.html @@ -6,10 +6,10 @@ Monte Carlo Simulation of Plasma Caffeine Concentrations by Using Population Pharmacokinetic Model • caffsim - + - - + @@ -24,18 +24,22 @@ - - + caffsim

@@ -86,8 +90,9 @@

Create a PK dataset for caffeine single dose

-
MyDataset <- caffsim::Dataset(Weight = 20, Dose = 200, N = 20)
-knitr::kable(head(MyDataset), format = "markdown")
+
library(caffsim)
+MyDataset <- caffDataset(Weight = 20, Dose = 200, N = 20)
+knitr::kable(head(MyDataset), format = "markdown")
@@ -101,64 +106,64 @@

- - - - - - - - + + + + + + + + - - - - - - - - + + + + + + + + - - - - - - - - + + + + + + + + - - - - - - - - + + + + + + + + - - - - - - - - + + + + + + + + - - - - - - - - + + + + + + + +
Tmax
0.42186418.77650259.348794.3839103.36990921.318009.98538830.15807810.207681917.32248076.823932.9258822.60335510.9915022.0711810.2368516
0.607278012.24005881.041404.1454042.46787514.762396.08677450.16717310.599723711.619144131.300507.4036541.52322316.273337.3749310.0936024
1.130030810.43019991.089755.2070912.19563716.497662.84212920.13308771.251230415.061971153.894416.1494561.29959211.532162.6303920.1126929
2.789091814.041108159.816555.5777471.25143510.072420.78534890.12424370.485723812.395174109.924455.7991831.81943215.225429.0218720.1194996
1.127388612.447478109.441675.2506481.82745713.846082.86046790.13198372.93659099.143911132.919397.7463061.50467116.819110.8602050.0894620
0.476802510.52489961.076523.6757833.27458117.368908.06643110.18853121.47295127.79884772.030355.2743432.77660721.132441.9694110.1313908
@@ -166,8 +171,8 @@

Create a dataset for concentration-time curve

-
MyConcTime <- ConcTime(Weight = 20, Dose = 200, N = 20)
-knitr::kable(head(MyConcTime), format = "markdown")
+
MyConcTime <- caffConcTime(Weight = 20, Dose = 200, N = 20)
+knitr::kable(head(MyConcTime), format = "markdown")
@@ -178,32 +183,32 @@

- + - + - + - + - + - +
Subject
1 0.00.000000.000000
1 0.111.052184.051225
1 0.212.280386.453208
1 0.312.166037.850944
1 0.411.874608.637601
1 0.511.566109.052837
@@ -211,8 +216,8 @@

Create a concentration-time curve

-
Plot(MyConcTime)
-

+
caffPlot(MyConcTime)
+

@@ -225,17 +230,17 @@

library(cowplot) MyPlotPub <- lapply( - c(seq(100, 800, by = 100)), - function(x) PlotMulti(ConcTime(20, x, 20)) + - theme(legend.position="none") + - labs(title = paste0("Single Dose ", x, "mg"))) + c(seq(100, 800, by = 100)), + function(x) caffPlotMulti(caffConcTime(20, x, 20)) + + theme(legend.position="none") + + labs(title = paste0("Single Dose ", x, "mg"))) -plot(plot_grid(MyPlotPub[[1]], MyPlotPub[[2]], - MyPlotPub[[3]], MyPlotPub[[4]], - MyPlotPub[[5]], MyPlotPub[[6]], - MyPlotPub[[7]], MyPlotPub[[8]], - labels=LETTERS[1:8], ncol = 2, nrow = 4))

-

+plot_grid(MyPlotPub[[1]], MyPlotPub[[2]], + MyPlotPub[[3]], MyPlotPub[[4]], + MyPlotPub[[5]], MyPlotPub[[6]], + MyPlotPub[[7]], MyPlotPub[[8]], + labels=LETTERS[1:8], ncol = 2, nrow = 4)

+

@@ -244,8 +249,8 @@

Create a PK dataset for caffeine multiple doses

-
MyDatasetMulti <- DatasetMulti(Weight = 20, Dose = 200, N = 20, Tau = 12)
-knitr::kable(head(MyDatasetMulti), format = "markdown")
+
MyDatasetMulti <- caffDatasetMulti(Weight = 20, Dose = 200, N = 20, Tau = 12)
+knitr::kable(head(MyDatasetMulti), format = "markdown")
@@ -259,64 +264,64 @@

- - - - - - - - + + + + + + + + - - - - - - - - + + + + + + + + - - - - - - - - + + + + + + + + - - - - - - - - + + + + + + + + - - - - - - - - + + + + + + + + - - - - - - - - + + + + + + + +
TmaxS
0.413350613.1794193.367631.197473110.734297.78063616.792842.76927171.465500311.24874299.066481.231604119.436798.25554016.9904263.1950640
1.135128810.8596178.859861.15726699.998246.57165515.178942.06273720.722673611.015475104.377631.338031145.065778.69813616.0122764.0452297
0.781613710.4862857.003121.07869476.237174.75026013.414510.97863281.98310196.75514486.608191.478804176.983597.21734912.0359673.8969791
0.463865522.88723200.639771.307403137.8686416.71998131.645027.44052972.008317310.220530120.366581.397277158.6963110.03054817.6264955.0116031
0.364362618.74429193.559511.427699165.5749616.12995927.758828.31577201.012595214.568618193.922141.601601203.8308916.16017825.3428929.5194178
0.421787012.6635083.496981.166063102.402306.95808115.813492.25205850.86383727.29599133.498561.03755060.134672.7915479.6129040.3478986
@@ -324,8 +329,8 @@

Create a dataset for concentration-time curve

-
MyConcTimeMulti <- ConcTimeMulti(Weight = 20, Dose = 200, N = 20, Tau = 12, Repeat = 10)
-knitr::kable(head(MyConcTimeMulti), format = "markdown")
+
MyConcTimeMulti <- caffConcTimeMulti(Weight = 20, Dose = 200, N = 20, Tau = 12, Repeat = 10)
+knitr::kable(head(MyConcTimeMulti), format = "markdown")
@@ -341,27 +346,27 @@

- + - + - + - + - +
Subject
1 0.23.5314979.355874
1 0.45.9435739.459559
1 0.67.5580339.074773
1 0.88.6051468.680297
1 1.09.2496488.301586
@@ -369,8 +374,8 @@

Create a concentration-time curve

-
PlotMulti(MyConcTimeMulti)
-

+
caffPlotMulti(MyConcTimeMulti)
+

@@ -383,17 +388,17 @@

library(cowplot) MyPlotMultiPub <- lapply( - c(seq(4, 32, by = 4)), - function(x) PlotMulti(ConcTimeMulti(20, 250, 20, x, 15)) + - theme(legend.position="none") + - labs(title = paste0("q", x, "hr" ))) + c(seq(4, 32, by = 4)), + function(x) caffPlotMulti(caffConcTimeMulti(20, 250, 20, x, 15)) + + theme(legend.position="none") + + labs(title = paste0("q", x, "hr" ))) -plot(plot_grid(MyPlotMultiPub[[1]], MyPlotMultiPub[[2]], - MyPlotMultiPub[[3]], MyPlotMultiPub[[4]], - MyPlotMultiPub[[5]], MyPlotMultiPub[[6]], - MyPlotMultiPub[[7]], MyPlotMultiPub[[8]], - labels=LETTERS[1:8], ncol = 2, nrow = 4))

-

+plot_grid(MyPlotMultiPub[[1]], MyPlotMultiPub[[2]], + MyPlotMultiPub[[3]], MyPlotMultiPub[[4]], + MyPlotMultiPub[[5]], MyPlotMultiPub[[6]], + MyPlotMultiPub[[7]], MyPlotMultiPub[[8]], + labels=LETTERS[1:8], ncol = 2, nrow = 4)

+

@@ -401,7 +406,8 @@

- diff --git a/docs/pkgdown.css b/docs/pkgdown.css index 24960c4..209ce57 100644 --- a/docs/pkgdown.css +++ b/docs/pkgdown.css @@ -1,132 +1,104 @@ -img.icon { - float: left; - margin-left: -35px; - width: 30px; - height: 30px; -} - -body {font-size: 16px;} -h1 {font-size: 40px;} -h2 {font-size: 30px;} - -/* Fixes for fixed navbar --------------------------*/ - -body { - position: relative; - padding-top: 65px; +/* Sticker footer */ +body > .container { + display: flex; + padding-top: 60px; + min-height: calc(100vh); + flex-direction: column; } -.contents h1, .contents h2, .contents h3, .contents h4 { - padding-top: 65px; - margin-top: -45px; +body > .container .row { + flex: 1; } -.page-header { - margin-top: 0; - margin-bottom: 10px; - padding-bottom: 0px; +footer { + margin-top: 45px; + padding: 35px 0 36px; + border-top: 1px solid #e5e5e5; + color: #666; + display: flex; } - -/* Static header placement on mobile devices */ -@media (max-width: 767px) { - .navbar-fixed-top { - position: absolute; - } +footer p { + margin-bottom: 0; } - -.navbar-toggle { - margin-top: 8px; - margin-bottom: 5px; +footer div { + flex: 1; } - -/* Table of contents --------------------------*/ - -#sidebar { - /* - Needed to avoid bug in sticky-kit: - https://github.com/leafo/sticky-kit/issues/169 - */ - position:static; +footer .pkgdown { + text-align: right; } - -#sidebar h2 { - font-size: 1.6em; - margin-top: 1em; - margin-bottom: 0.25em; +footer p { + margin-bottom: 0; } -#sidebar .list-unstyled li { - margin-bottom: 0.5em; - line-height: 1.4; +img.icon { + float: right; } -#sidebar small { - color: #777; +img { + max-width: 100%; } -/* Syntax highlighting ---------------------------------------------------- */ +/* Section anchors ---------------------------------*/ -pre { - word-wrap: normal; - word-break: normal; - border: none; -} +a.anchor { + margin-left: -30px; + display:inline-block; + width: 30px; + height: 30px; + visibility: hidden; -pre, code { - background-color: #fafafa; - color: #000000; - -webkit-font-smoothing: subpixel-antialiased; + background-image: url(./link.svg); + background-repeat: no-repeat; + background-size: 20px 20px; + background-position: center center; } -pre img { - background-color: #fff; - display: block; +.hasAnchor:hover a.anchor { + visibility: visible; } -code a, pre a { - color: #375f84; +@media (max-width: 767px) { + .hasAnchor:hover a.anchor { + visibility: hidden; + } } -.fl {color: #1514b5;} -.fu {color: #000000;} /* function */ -.ch,.st {color: #036a07;} /* string */ -.kw {color: #264D66;} /* keyword */ -.co {color: #777777;} /* comment */ - -.message { color: black; font-weight: bolder;} -.error { color: orange; font-weight: bolder;} -.warning { color: orange; font-weight: normal;} +/* Fixes for fixed navbar --------------------------*/ -/* Status --------------------------- */ - -.status-container { - padding-top:32px; +.contents h1, .contents h2, .contents h3, .contents h4 { + padding-top: 60px; + margin-top: -60px; } -.status-container a { - display: block; - margin-bottom: 5px; +/* Static header placement on mobile devices */ +@media (max-width: 767px) { + .navbar-fixed-top { + position: absolute; + } + .navbar { + padding: 0; + } } -/* For shrinking navbar ------------------ */ -/* For big header +/* Sidebar --------------------------*/ - &-brand { - font-family: $font-family-monospace; - font-weight: normal; - font-size: 48px; - padding: 35px 15px; +#sidebar { + margin-top: 30px; +} +#sidebar h2 { + font-size: 1.5em; + margin-top: 1em; +} - padding-left: 84px; - background-image:url(../logo.png); - background-size: 60px auto; - background-repeat: no-repeat; - background-position: 15px center; +#sidebar h2:first-child { + margin-top: 0; +} - } -*/ +#sidebar .list-unstyled li { + margin-bottom: 0.5em; +} /* Reference index & topics ----------------------------------------------- */ @@ -142,81 +114,50 @@ code a, pre a { .ref-arguments th {text-align: right; padding-right: 10px;} .ref-arguments th, .ref-arguments td {vertical-align: top;} -.ref-arguments .name {width: 10%;} -.ref-arguments .desc {width: 90%;} +.ref-arguments .name {width: 20%;} +.ref-arguments .desc {width: 80%;} -/* For the rstudio footer ------- */ +/* Nice scrolling for wide elements --------------------------------------- */ -footer { - margin-top: 45px; - padding: 35px 0 36px; - border-top: 1px solid #e5e5e5; - - display: flex; - color: #666; -} -footer p { - margin-bottom: 0; -} -footer .tidyverse { - flex: 1; -} -footer .author { - flex: 1; - text-align: right; +table { + display: block; + overflow: auto; } -/* ---------------------- hover anchor tags */ +/* Syntax highlighting ---------------------------------------------------- */ -.hasAnchor { - margin-left: -30px; +pre { + word-wrap: normal; + word-break: normal; + border: 1px solid #eee; } -a.anchor { - display:inline-block; - width: 30px; - height: 30px; - visibility: hidden; - - background-image: url(./link.svg); - background-repeat: no-repeat; - background-size: 20px 20px; - background-position: center center; +pre, code { + background-color: #f8f8f8; + color: #333; } -.hasAnchor:hover a.anchor { - visibility: visible; +pre .img { + margin: 5px 0; } -/* Tweak appearance of navigation in sidebar ---------------------- */ - -#sidebar .nav { - padding-left: 0px; - list-style-type: none; - color: #5a9ddb; +pre .img img { + background-color: #fff; + display: block; + height: auto; } -#sidebar .nav > li { - padding: 10px 0 0px 20px; - display: list-item; - line-height: 20px; - background-image: url(./tocBullet.svg); - background-repeat: no-repeat; - background-size: 16px 280px; - background-position: left 0px; +code a, pre a { + color: #375f84; } -#sidebar .nav > li.active { - background-position: left -240px; -} +.fl {color: #1514b5;} +.fu {color: #000000;} /* function */ +.ch,.st {color: #036a07;} /* string */ +.kw {color: #264D66;} /* keyword */ +.co {color: #888888;} /* comment */ -#sidebar a { - padding: 0px; - color: #5a9ddb; - background-color: transparent; -} +.message { color: black; font-weight: bolder;} +.error { color: orange; font-weight: bolder;} +.warning { color: #6A0366; font-weight: bolder;} -#sidebar a:hover { - background-color: transparent; - text-decoration: underline; -} diff --git a/docs/pkgdown.js b/docs/pkgdown.js index da3b067..4b81713 100644 --- a/docs/pkgdown.js +++ b/docs/pkgdown.js @@ -1,8 +1,45 @@ $(function() { - $("#sidebar").stick_in_parent({ - offset_top: $("#sidebar").offset().top - }); + $("#sidebar").stick_in_parent({offset_top: 40}); $('body').scrollspy({ - target: '#sidebar' + target: '#sidebar', + offset: 60 + }); + + var cur_path = paths(location.pathname); + $("#navbar ul li a").each(function(index, value) { + if (value.text == "Home") + return; + if (value.getAttribute("href") === "#") + return; + + var path = paths(value.pathname); + if (is_prefix(cur_path, path)) { + // Add class to parent
  • , and enclosing
  • if in dropdown + var menu_anchor = $(value); + menu_anchor.parent().addClass("active"); + menu_anchor.closest("li.dropdown").addClass("active"); + } }); }); + +function paths(pathname) { + var pieces = pathname.split("/"); + pieces.shift(); // always starts with / + + var end = pieces[pieces.length - 1]; + if (end === "index.html" || end === "") + pieces.pop(); + return(pieces); +} + +function is_prefix(needle, haystack) { + if (needle.length > haystack.lengh) + return(false); + + for (var i = 0; i < haystack.length; i++) { + if (needle[i] != haystack[i]) + return(false); + } + + return(true); +} diff --git a/docs/reference/Plot-2.png b/docs/reference/Plot-2.png deleted file mode 100644 index 994aa41..0000000 Binary files a/docs/reference/Plot-2.png and /dev/null differ diff --git a/docs/reference/PlotMulti-2.png b/docs/reference/PlotMulti-2.png deleted file mode 100644 index 5e7cbea..0000000 Binary files a/docs/reference/PlotMulti-2.png and /dev/null differ diff --git a/docs/reference/UnitTable.html b/docs/reference/UnitTable.html index a6d30ff..1a2bfc4 100644 --- a/docs/reference/UnitTable.html +++ b/docs/reference/UnitTable.html @@ -6,30 +6,34 @@ -Unit data of PK parameters <U+2014> UnitTable bcaffsim +Unit data of PK parameters <U+2014> UnitTable <e2><80><a2> caffsim - - + + - + + - + + - + + + @@ -43,17 +47,22 @@ - - + caffsim @@ -99,31 +108,21 @@

    Contents

  • Format
  • -
  • Source
  • +
  • See also
  • diff --git a/docs/reference/ConcTime.html b/docs/reference/caffConcTime.html similarity index 99% rename from docs/reference/ConcTime.html rename to docs/reference/caffConcTime.html index 8fbc559..6caac1d 100644 --- a/docs/reference/ConcTime.html +++ b/docs/reference/caffConcTime.html @@ -6,30 +6,34 @@ -Create a dataset of the concentration-time curve <U+2014> ConcTime bcaffsim +Create a dataset of the concentration-time curve of single oral administration of caffeine <U+2014> caffConcTime <e2><80><a2> caffsim - - + + - + + - + + - + + + @@ -43,17 +47,22 @@ - - + caffsim diff --git a/docs/reference/index.html b/docs/reference/index.html index 61960c6..87ad6e8 100644 --- a/docs/reference/index.html +++ b/docs/reference/index.html @@ -10,26 +10,30 @@ - - + + - + + - + + - + + + @@ -43,17 +47,22 @@ - - + caffsim diff --git a/docs/tidyverse.css b/docs/tidyverse.css deleted file mode 100644 index 1e69196..0000000 --- a/docs/tidyverse.css +++ /dev/null @@ -1,6496 +0,0 @@ -@charset "UTF-8"; -/*! - * Bootstrap v3.3.7 (http://getbootstrap.com) - * Copyright 2011-2016 Twitter, Inc. - * Licensed under MIT (https://github.com/twbs/bootstrap/blob/master/LICENSE) - */ -/*! normalize.css v3.0.3 | MIT License | github.com/necolas/normalize.css */ -@import url("https://fonts.googleapis.com/css?family=Source+Code+Pro:300,400,700|Source+Sans+Pro:300,400,700"); -html { - font-family: sans-serif; - -ms-text-size-adjust: 100%; - -webkit-text-size-adjust: 100%; } - -body { - margin: 0; } - -article, -aside, -details, -figcaption, -figure, -footer, -header, -hgroup, -main, -menu, -nav, -section, -summary { - display: block; } - -audio, -canvas, -progress, -video { - display: inline-block; - vertical-align: baseline; } - -audio:not([controls]) { - display: none; - height: 0; } - -[hidden], -template { - display: none; } - -a { - background-color: transparent; } - -a:active, -a:hover { - outline: 0; } - -abbr[title] { - border-bottom: 1px dotted; } - -b, -strong { - font-weight: bold; } - -dfn { - font-style: italic; } - -h1 { - font-size: 2em; - margin: 0.67em 0; } - -mark { - background: #ff0; - color: #000; } - -small { - font-size: 80%; } - -sub, -sup { - font-size: 75%; - line-height: 0; - position: relative; - vertical-align: baseline; } - -sup { - top: -0.5em; } - -sub { - bottom: -0.25em; } - -img { - border: 0; } - -svg:not(:root) { - overflow: hidden; } - -figure { - margin: 1em 40px; } - -hr { - box-sizing: content-box; - height: 0; } - -pre { - overflow: auto; } - -code, -kbd, -pre, -samp { - font-family: monospace, monospace; - font-size: 1em; } - -button, -input, -optgroup, -select, -textarea { - color: inherit; - font: inherit; - margin: 0; } - -button { - overflow: visible; } - -button, -select { - text-transform: none; } - -button, -html input[type="button"], -input[type="reset"], -input[type="submit"] { - -webkit-appearance: button; - cursor: pointer; } - -button[disabled], -html input[disabled] { - cursor: default; } - -button::-moz-focus-inner, -input::-moz-focus-inner { - border: 0; - padding: 0; } - -input { - line-height: normal; } - -input[type="checkbox"], -input[type="radio"] { - box-sizing: border-box; - padding: 0; } - -input[type="number"]::-webkit-inner-spin-button, -input[type="number"]::-webkit-outer-spin-button { - height: auto; } - -input[type="search"] { - -webkit-appearance: textfield; - box-sizing: content-box; } - -input[type="search"]::-webkit-search-cancel-button, -input[type="search"]::-webkit-search-decoration { - -webkit-appearance: none; } - -fieldset { - border: 1px solid #c0c0c0; - margin: 0 2px; - padding: 0.35em 0.625em 0.75em; } - -legend { - border: 0; - padding: 0; } - -textarea { - overflow: auto; } - -optgroup { - font-weight: bold; } - -table { - border-collapse: collapse; - border-spacing: 0; } - -td, -th { - padding: 0; } - -/*! 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margin-bottom: 13.5px; } - h4 small, - h4 .small, .h4 small, - .h4 .small, - h5 small, - h5 .small, .h5 small, - .h5 .small, - h6 small, - h6 .small, .h6 small, - .h6 .small { - font-size: 75%; } - -h1, .h1 { - font-size: 48px; } - -h2, .h2 { - font-size: 40px; } - -h3, .h3 { - font-size: 32px; } - -h4, .h4 { - font-size: 24px; } - -h5, .h5 { - font-size: 20px; } - -h6, .h6 { - font-size: 14px; } - -p { - margin: 0 0 13.5px; } - -.lead { - margin-bottom: 27px; - font-size: 17px; - font-weight: 300; - line-height: 1.4; } - @media (min-width: 768px) { - .lead { - font-size: 22.5px; } } - -small, -.small { - font-size: 86%; } - -mark, -.mark { - background-color: #ffe0b2; - padding: .2em; } - -.text-left { - text-align: left; } - -.text-right { - text-align: right; } - -.text-center { - text-align: center; } - -.text-justify { - text-align: justify; } - -.text-nowrap { - white-space: nowrap; } - -.text-lowercase { - text-transform: lowercase; } - -.text-uppercase, .initialism { - text-transform: uppercase; } - -.text-capitalize { - text-transform: capitalize; } - -.text-muted { - color: #bbb; } - -.text-primary { - color: #5a9ddb; } - -a.text-primary:hover, -a.text-primary:focus { - color: #3084d2; } - -.text-success { - color: #4CAF50; } - -a.text-success:hover, -a.text-success:focus { - color: #3d8b40; } - -.text-info { - color: #9C27B0; } - -a.text-info:hover, -a.text-info:focus { - color: #771e86; } - -.text-warning { - color: #ff9800; } - -a.text-warning:hover, -a.text-warning:focus { - color: #cc7a00; } - -.text-danger { - color: #e51c23; } - -a.text-danger:hover, -a.text-danger:focus { - color: #b9151b; } - -.bg-primary { - color: #fff; } - -.bg-primary { - background-color: #5a9ddb; } - -a.bg-primary:hover, -a.bg-primary:focus { - background-color: #3084d2; } - -.bg-success { - background-color: #dff0d8; } - -a.bg-success:hover, -a.bg-success:focus { - background-color: #c1e2b3; } - -.bg-info { - background-color: #e1bee7; } - -a.bg-info:hover, -a.bg-info:focus { - background-color: #d099d9; } - -.bg-warning { - background-color: #ffe0b2; } - -a.bg-warning:hover, -a.bg-warning:focus { - background-color: #ffcb7f; } - -.bg-danger { - background-color: #f9bdbb; } - -a.bg-danger:hover, -a.bg-danger:focus { - background-color: #f5908c; } - -.page-header { - padding-bottom: 12.5px; - margin: 54px 0 27px; - border-bottom: 1px solid #eeeeee; } - -ul, -ol { - margin-top: 0; - margin-bottom: 13.5px; } - ul ul, - ul ol, - ol ul, - ol ol { - margin-bottom: 0; } - -.list-unstyled { - padding-left: 0; - list-style: none; } - -.list-inline { - padding-left: 0; - list-style: none; - margin-left: -5px; } - .list-inline > li { - display: inline-block; - padding-left: 5px; - padding-right: 5px; } - -dl { - margin-top: 0; - margin-bottom: 27px; } - -dt, -dd { - line-height: 1.846; } - -dt { - font-weight: bold; } - -dd { - margin-left: 0; } - -.dl-horizontal dd:before, .dl-horizontal dd:after { - content: " "; - display: table; } -.dl-horizontal dd:after { - clear: both; } -@media (min-width: 768px) { - .dl-horizontal dt { - float: left; - width: 160px; - clear: left; - text-align: right; - overflow: hidden; - text-overflow: ellipsis; - white-space: nowrap; } - .dl-horizontal dd { - margin-left: 180px; } } - -abbr[title], -abbr[data-original-title] { - cursor: help; - border-bottom: 1px dotted #bbb; } - -.initialism { - font-size: 90%; } - -blockquote { - padding: 13.5px 27px; - margin: 0 0 27px; - font-size: 18.75px; - border-left: 5px solid #eeeeee; } - blockquote p:last-child, - blockquote ul:last-child, - blockquote ol:last-child { - margin-bottom: 0; } - blockquote footer, - blockquote small, - blockquote .small { - display: block; - font-size: 80%; - line-height: 1.846; - color: #bbb; } - blockquote footer:before, - blockquote small:before, - blockquote .small:before { - content: '\2014 \00A0'; } - -.blockquote-reverse, -blockquote.pull-right { - padding-right: 15px; - padding-left: 0; - border-right: 5px solid #eeeeee; - border-left: 0; - text-align: right; } - .blockquote-reverse footer:before, - .blockquote-reverse small:before, - .blockquote-reverse .small:before, - blockquote.pull-right footer:before, - blockquote.pull-right small:before, - blockquote.pull-right .small:before { - content: ''; } - .blockquote-reverse footer:after, - .blockquote-reverse small:after, - .blockquote-reverse .small:after, - blockquote.pull-right footer:after, - blockquote.pull-right small:after, - blockquote.pull-right .small:after { - content: '\00A0 \2014'; } - -address { - margin-bottom: 27px; - font-style: normal; - line-height: 1.846; } - -code, -kbd, -pre, -samp { - font-family: "Source Code Pro", Menlo, Monaco, Consolas, "Courier New", monospace; } - -code { - padding: 2px 4px; - font-size: 90%; - color: #444; - background-color: #f2f2f2; - border-radius: 3px; } - -kbd { - padding: 2px 4px; - font-size: 90%; - color: #fff; - background-color: #333; - border-radius: 3px; - box-shadow: inset 0 -1px 0 rgba(0, 0, 0, 0.25); } - kbd kbd { - padding: 0; - font-size: 100%; - font-weight: bold; - box-shadow: none; } - -pre { - display: block; - padding: 13px; - margin: 0 0 13.5px; - font-size: 14px; - line-height: 1.846; - word-break: break-all; - word-wrap: break-word; - color: #212121; - background-color: #f5f5f5; - border: 1px solid #ccc; - border-radius: 3px; } - pre code { - padding: 0; - font-size: inherit; - color: inherit; - white-space: pre-wrap; - background-color: transparent; - border-radius: 0; } - -.pre-scrollable { - max-height: 340px; - overflow-y: scroll; } - -.container { - margin-right: auto; - margin-left: auto; - padding-left: 15px; - padding-right: 15px; } - .container:before, .container:after { - content: " "; - display: table; } - .container:after { - clear: both; } - @media (min-width: 768px) { - .container { - width: 750px; } } - @media (min-width: 992px) { - .container { - width: 970px; } } - @media (min-width: 1200px) { - .container { - width: 1170px; } } - -.container-fluid { - margin-right: auto; - margin-left: auto; - padding-left: 15px; - padding-right: 15px; } - .container-fluid:before, .container-fluid:after { - content: " "; - display: table; } - .container-fluid:after { - clear: both; } - -.row { - margin-left: -15px; - margin-right: -15px; } - .row:before, .row:after { - content: " "; - display: table; } - .row:after { - clear: both; } - -.col-xs-1, .col-sm-1, .col-md-1, .col-lg-1, .col-xs-2, .col-sm-2, .col-md-2, .col-lg-2, .col-xs-3, .col-sm-3, .col-md-3, .col-lg-3, .col-xs-4, .col-sm-4, .col-md-4, .col-lg-4, .col-xs-5, .col-sm-5, .col-md-5, .col-lg-5, .col-xs-6, .col-sm-6, .col-md-6, .col-lg-6, .col-xs-7, .col-sm-7, .col-md-7, .col-lg-7, .col-xs-8, .col-sm-8, .col-md-8, .col-lg-8, .col-xs-9, .col-sm-9, .col-md-9, .col-lg-9, .col-xs-10, .col-sm-10, .col-md-10, .col-lg-10, .col-xs-11, .col-sm-11, .col-md-11, .col-lg-11, .col-xs-12, .col-sm-12, .col-md-12, .col-lg-12 { - position: relative; - min-height: 1px; - padding-left: 15px; - padding-right: 15px; } - -.col-xs-1, .col-xs-2, .col-xs-3, .col-xs-4, .col-xs-5, .col-xs-6, .col-xs-7, .col-xs-8, .col-xs-9, .col-xs-10, .col-xs-11, .col-xs-12 { - float: left; } - -.col-xs-1 { - width: 8.33333%; } - -.col-xs-2 { - width: 16.66667%; } - -.col-xs-3 { - width: 25%; } - -.col-xs-4 { - width: 33.33333%; } - -.col-xs-5 { - width: 41.66667%; } - -.col-xs-6 { - width: 50%; } - -.col-xs-7 { - width: 58.33333%; } - -.col-xs-8 { - width: 66.66667%; } - -.col-xs-9 { - width: 75%; } - -.col-xs-10 { - width: 83.33333%; } - -.col-xs-11 { - width: 91.66667%; } - -.col-xs-12 { - width: 100%; } - -.col-xs-pull-0 { - right: auto; } - -.col-xs-pull-1 { - right: 8.33333%; } - -.col-xs-pull-2 { - right: 16.66667%; } - -.col-xs-pull-3 { - right: 25%; } - -.col-xs-pull-4 { - right: 33.33333%; } - -.col-xs-pull-5 { - right: 41.66667%; } - -.col-xs-pull-6 { - right: 50%; } - -.col-xs-pull-7 { - right: 58.33333%; } - -.col-xs-pull-8 { - right: 66.66667%; } - -.col-xs-pull-9 { - right: 75%; } - -.col-xs-pull-10 { - right: 83.33333%; } - -.col-xs-pull-11 { - right: 91.66667%; } - -.col-xs-pull-12 { - right: 100%; } - -.col-xs-push-0 { - left: auto; } - -.col-xs-push-1 { - left: 8.33333%; } - -.col-xs-push-2 { - left: 16.66667%; } - -.col-xs-push-3 { - left: 25%; } - -.col-xs-push-4 { - left: 33.33333%; } - -.col-xs-push-5 { - left: 41.66667%; } - -.col-xs-push-6 { - left: 50%; } - -.col-xs-push-7 { - left: 58.33333%; } - -.col-xs-push-8 { - left: 66.66667%; } - -.col-xs-push-9 { - left: 75%; } - -.col-xs-push-10 { - left: 83.33333%; } - -.col-xs-push-11 { - left: 91.66667%; } - -.col-xs-push-12 { - left: 100%; } - -.col-xs-offset-0 { - margin-left: 0%; } - -.col-xs-offset-1 { - margin-left: 8.33333%; } - -.col-xs-offset-2 { - margin-left: 16.66667%; } - -.col-xs-offset-3 { - margin-left: 25%; } - -.col-xs-offset-4 { - margin-left: 33.33333%; } - -.col-xs-offset-5 { - margin-left: 41.66667%; } - -.col-xs-offset-6 { - margin-left: 50%; } - -.col-xs-offset-7 { - margin-left: 58.33333%; } - -.col-xs-offset-8 { - margin-left: 66.66667%; } - -.col-xs-offset-9 { - margin-left: 75%; } - -.col-xs-offset-10 { - margin-left: 83.33333%; } - -.col-xs-offset-11 { - margin-left: 91.66667%; } - -.col-xs-offset-12 { - margin-left: 100%; } - -@media (min-width: 768px) { - .col-sm-1, .col-sm-2, .col-sm-3, .col-sm-4, .col-sm-5, .col-sm-6, .col-sm-7, .col-sm-8, .col-sm-9, .col-sm-10, .col-sm-11, .col-sm-12 { - float: left; } - - .col-sm-1 { - width: 8.33333%; } - - .col-sm-2 { - width: 16.66667%; } - - .col-sm-3 { - width: 25%; } - - .col-sm-4 { - width: 33.33333%; } - - .col-sm-5 { - width: 41.66667%; } - - .col-sm-6 { - width: 50%; } - - .col-sm-7 { - width: 58.33333%; } - - .col-sm-8 { - width: 66.66667%; } - - .col-sm-9 { - width: 75%; } - - .col-sm-10 { - width: 83.33333%; } - - .col-sm-11 { - width: 91.66667%; } - - .col-sm-12 { - width: 100%; } - - .col-sm-pull-0 { - right: auto; } - - .col-sm-pull-1 { - right: 8.33333%; } - - .col-sm-pull-2 { - right: 16.66667%; } - - .col-sm-pull-3 { - right: 25%; } - - .col-sm-pull-4 { - right: 33.33333%; } - - .col-sm-pull-5 { - right: 41.66667%; } - - .col-sm-pull-6 { - right: 50%; } - - .col-sm-pull-7 { - right: 58.33333%; } - - .col-sm-pull-8 { - right: 66.66667%; } - - .col-sm-pull-9 { - right: 75%; } - - .col-sm-pull-10 { - right: 83.33333%; } - - .col-sm-pull-11 { - right: 91.66667%; } - - .col-sm-pull-12 { - right: 100%; } - - .col-sm-push-0 { - left: auto; } - - .col-sm-push-1 { - left: 8.33333%; } - - .col-sm-push-2 { - left: 16.66667%; } - - .col-sm-push-3 { - left: 25%; } - - .col-sm-push-4 { - left: 33.33333%; } - - .col-sm-push-5 { - left: 41.66667%; } - - .col-sm-push-6 { - left: 50%; } - - .col-sm-push-7 { - left: 58.33333%; } - - .col-sm-push-8 { - left: 66.66667%; } - - .col-sm-push-9 { - left: 75%; } - - .col-sm-push-10 { - left: 83.33333%; } - - .col-sm-push-11 { - left: 91.66667%; } - - .col-sm-push-12 { - left: 100%; } - - .col-sm-offset-0 { - margin-left: 0%; } - - .col-sm-offset-1 { - margin-left: 8.33333%; } - - .col-sm-offset-2 { - margin-left: 16.66667%; } - - .col-sm-offset-3 { - margin-left: 25%; } - - .col-sm-offset-4 { - margin-left: 33.33333%; } - - .col-sm-offset-5 { - margin-left: 41.66667%; } - - .col-sm-offset-6 { - margin-left: 50%; } - - .col-sm-offset-7 { - margin-left: 58.33333%; } - - .col-sm-offset-8 { - margin-left: 66.66667%; } - - .col-sm-offset-9 { - margin-left: 75%; } - - .col-sm-offset-10 { - margin-left: 83.33333%; } - - .col-sm-offset-11 { - margin-left: 91.66667%; } - - .col-sm-offset-12 { - margin-left: 100%; } } -@media (min-width: 992px) { - .col-md-1, .col-md-2, .col-md-3, .col-md-4, .col-md-5, .col-md-6, .col-md-7, .col-md-8, .col-md-9, .col-md-10, .col-md-11, .col-md-12 { - float: left; } - - .col-md-1 { - width: 8.33333%; } - - .col-md-2 { - width: 16.66667%; } - - .col-md-3 { - width: 25%; } - - .col-md-4 { - width: 33.33333%; } - - .col-md-5 { - width: 41.66667%; } - - .col-md-6 { - width: 50%; } - - .col-md-7 { - width: 58.33333%; } - - .col-md-8 { - width: 66.66667%; } - - .col-md-9 { - width: 75%; } - - .col-md-10 { - width: 83.33333%; } - - .col-md-11 { - width: 91.66667%; } - - .col-md-12 { - width: 100%; } - - .col-md-pull-0 { - right: auto; } - - .col-md-pull-1 { - right: 8.33333%; } - - .col-md-pull-2 { - right: 16.66667%; } - - .col-md-pull-3 { - right: 25%; } - - .col-md-pull-4 { - right: 33.33333%; } - - .col-md-pull-5 { - right: 41.66667%; } - - .col-md-pull-6 { - right: 50%; } - - .col-md-pull-7 { - right: 58.33333%; } - - .col-md-pull-8 { - right: 66.66667%; } - - .col-md-pull-9 { - right: 75%; } - - .col-md-pull-10 { - right: 83.33333%; } - - .col-md-pull-11 { - right: 91.66667%; } - - .col-md-pull-12 { - right: 100%; } - - .col-md-push-0 { - left: auto; } - - .col-md-push-1 { - left: 8.33333%; } - - .col-md-push-2 { - left: 16.66667%; } - - .col-md-push-3 { - left: 25%; } - - .col-md-push-4 { - left: 33.33333%; } - - .col-md-push-5 { - left: 41.66667%; } - - .col-md-push-6 { - left: 50%; } - - .col-md-push-7 { - left: 58.33333%; } - - .col-md-push-8 { - left: 66.66667%; } - - .col-md-push-9 { - left: 75%; } - - .col-md-push-10 { - left: 83.33333%; } - - .col-md-push-11 { - left: 91.66667%; } - - .col-md-push-12 { - left: 100%; } - - .col-md-offset-0 { - margin-left: 0%; } - - .col-md-offset-1 { - margin-left: 8.33333%; } - - .col-md-offset-2 { - margin-left: 16.66667%; } - - .col-md-offset-3 { - margin-left: 25%; } - - .col-md-offset-4 { - margin-left: 33.33333%; } - - .col-md-offset-5 { - margin-left: 41.66667%; } - - .col-md-offset-6 { - margin-left: 50%; } - - .col-md-offset-7 { - margin-left: 58.33333%; } - - .col-md-offset-8 { - margin-left: 66.66667%; } - - .col-md-offset-9 { - margin-left: 75%; } - - .col-md-offset-10 { - margin-left: 83.33333%; } - - .col-md-offset-11 { - margin-left: 91.66667%; } - - .col-md-offset-12 { - margin-left: 100%; } } -@media (min-width: 1200px) { - .col-lg-1, .col-lg-2, .col-lg-3, .col-lg-4, .col-lg-5, .col-lg-6, .col-lg-7, .col-lg-8, .col-lg-9, .col-lg-10, .col-lg-11, .col-lg-12 { - float: left; } - - .col-lg-1 { - width: 8.33333%; } - - .col-lg-2 { - width: 16.66667%; } - - .col-lg-3 { - width: 25%; } - - .col-lg-4 { - width: 33.33333%; } - - .col-lg-5 { - width: 41.66667%; } - - .col-lg-6 { - width: 50%; } - - .col-lg-7 { - width: 58.33333%; } - - .col-lg-8 { - width: 66.66667%; } - - .col-lg-9 { - width: 75%; } - - .col-lg-10 { - width: 83.33333%; } - - .col-lg-11 { - width: 91.66667%; } - - .col-lg-12 { - width: 100%; } - - .col-lg-pull-0 { - right: auto; } - - .col-lg-pull-1 { - right: 8.33333%; } - - .col-lg-pull-2 { - right: 16.66667%; } - - .col-lg-pull-3 { - right: 25%; } - - .col-lg-pull-4 { - right: 33.33333%; } - - .col-lg-pull-5 { - right: 41.66667%; } - - .col-lg-pull-6 { - right: 50%; } - - .col-lg-pull-7 { - right: 58.33333%; } - - .col-lg-pull-8 { - right: 66.66667%; } - - .col-lg-pull-9 { - right: 75%; } - - .col-lg-pull-10 { - right: 83.33333%; } - - .col-lg-pull-11 { - right: 91.66667%; } - - .col-lg-pull-12 { - right: 100%; } - - .col-lg-push-0 { - left: auto; } - - .col-lg-push-1 { - left: 8.33333%; } - - .col-lg-push-2 { - left: 16.66667%; } - - .col-lg-push-3 { - left: 25%; } - - .col-lg-push-4 { - left: 33.33333%; } - - .col-lg-push-5 { - left: 41.66667%; } - - .col-lg-push-6 { - left: 50%; } - - .col-lg-push-7 { - left: 58.33333%; } - - .col-lg-push-8 { - left: 66.66667%; } - - .col-lg-push-9 { - left: 75%; } - - .col-lg-push-10 { - left: 83.33333%; } - - .col-lg-push-11 { - left: 91.66667%; } - - .col-lg-push-12 { - left: 100%; } - - .col-lg-offset-0 { - margin-left: 0%; } - - .col-lg-offset-1 { - margin-left: 8.33333%; } - - .col-lg-offset-2 { - margin-left: 16.66667%; } - - .col-lg-offset-3 { - margin-left: 25%; } - - .col-lg-offset-4 { - margin-left: 33.33333%; } - - .col-lg-offset-5 { - margin-left: 41.66667%; } - - .col-lg-offset-6 { - margin-left: 50%; } - - .col-lg-offset-7 { - margin-left: 58.33333%; } - - .col-lg-offset-8 { - margin-left: 66.66667%; } - - .col-lg-offset-9 { - margin-left: 75%; } - - .col-lg-offset-10 { - margin-left: 83.33333%; } - - .col-lg-offset-11 { - margin-left: 91.66667%; } - - .col-lg-offset-12 { - margin-left: 100%; } } -table { - background-color: transparent; } - -caption { - padding-top: 8px; - padding-bottom: 8px; - color: #bbb; - text-align: left; } - -th { - text-align: left; } - -.table { - width: 100%; - max-width: 100%; - margin-bottom: 27px; } - .table > thead > tr > th, - .table > thead > tr > td, - .table > tbody > tr > th, - .table > tbody > tr > td, - .table > tfoot > tr > th, - .table > tfoot > tr > td { - padding: 8px; - line-height: 1.846; - vertical-align: top; - border-top: 1px solid #ddd; } - .table > thead > tr > th { - vertical-align: bottom; - border-bottom: 2px solid #ddd; } - .table > caption + thead > tr:first-child > th, - .table > caption + thead > tr:first-child > td, - .table > colgroup + thead > tr:first-child > th, - .table > colgroup + thead > tr:first-child > td, - .table > thead:first-child > tr:first-child > th, - .table > thead:first-child > tr:first-child > td { - border-top: 0; } - .table > tbody + tbody { - border-top: 2px solid #ddd; } - .table .table { - background-color: #fff; } - -.table-condensed > thead > tr > th, -.table-condensed > thead > tr > td, -.table-condensed > tbody > tr > th, -.table-condensed > tbody > tr > td, -.table-condensed > tfoot > tr > th, -.table-condensed > tfoot > tr > td { - padding: 5px; } - -.table-bordered { - border: 1px solid #ddd; } - .table-bordered > thead > tr > th, - .table-bordered > thead > tr > td, - .table-bordered > tbody > tr > th, - .table-bordered > tbody > tr > td, - .table-bordered > tfoot > tr > th, - .table-bordered > tfoot > tr > td { - border: 1px solid #ddd; } - .table-bordered > thead > tr > th, - .table-bordered > thead > tr > td { - border-bottom-width: 2px; } - -.table-striped > tbody > tr:nth-of-type(odd) { - background-color: #f9f9f9; } - -.table-hover > tbody > tr:hover { - background-color: #f5f5f5; } - -table col[class*="col-"] { - position: static; - float: none; - display: table-column; } - -table td[class*="col-"], -table th[class*="col-"] { - position: static; - float: none; - display: table-cell; } - -.table > thead > tr > td.active, -.table > thead > tr > th.active, .table > thead > tr.active > td, .table > thead > tr.active > th, -.table > tbody > tr > td.active, -.table > tbody > tr > th.active, -.table > tbody > tr.active > td, -.table > tbody > tr.active > th, -.table > tfoot > tr > td.active, -.table > tfoot > tr > th.active, -.table > tfoot > tr.active > td, -.table > tfoot > tr.active > th { - background-color: #f5f5f5; } - -.table-hover > tbody > tr > td.active:hover, -.table-hover > tbody > tr > th.active:hover, .table-hover > tbody > tr.active:hover > td, .table-hover > tbody > tr:hover > .active, .table-hover > tbody > tr.active:hover > th { - background-color: #e8e8e8; } - -.table > thead > tr > td.success, -.table > thead > tr > th.success, .table > thead > tr.success > td, .table > thead > tr.success > th, -.table > tbody > tr > td.success, -.table > tbody > tr > th.success, -.table > tbody > tr.success > td, -.table > tbody > tr.success > th, -.table > tfoot > tr > td.success, -.table > tfoot > tr > th.success, -.table > tfoot > tr.success > td, -.table > tfoot > tr.success > th { - background-color: #dff0d8; } - -.table-hover > tbody > tr > td.success:hover, -.table-hover > tbody > tr > th.success:hover, .table-hover > tbody > tr.success:hover > td, .table-hover > tbody > tr:hover > .success, .table-hover > tbody > tr.success:hover > th { - background-color: #d0e9c6; } - -.table > thead > tr > td.info, -.table > thead > tr > th.info, .table > thead > tr.info > td, .table > thead > tr.info > th, -.table > tbody > tr > td.info, -.table > tbody > tr > th.info, -.table > tbody > tr.info > td, -.table > tbody > tr.info > th, -.table > tfoot > tr > td.info, -.table > tfoot > tr > th.info, -.table > tfoot > tr.info > td, -.table > tfoot > tr.info > th { - background-color: #e1bee7; } - -.table-hover > tbody > tr > td.info:hover, -.table-hover > tbody > tr > th.info:hover, .table-hover > tbody > tr.info:hover > td, .table-hover > tbody > tr:hover > .info, .table-hover > tbody > tr.info:hover > th { - background-color: #d8abe0; } - -.table > thead > tr > td.warning, -.table > thead > tr > th.warning, .table > thead > tr.warning > td, .table > thead > tr.warning > th, -.table > tbody > tr > td.warning, -.table > tbody > tr > th.warning, -.table > tbody > tr.warning > td, -.table > tbody > tr.warning > th, -.table > tfoot > tr > td.warning, -.table > tfoot > tr > th.warning, -.table > tfoot > tr.warning > td, -.table > tfoot > tr.warning > th { - background-color: #ffe0b2; } - -.table-hover > tbody > tr > td.warning:hover, -.table-hover > tbody > tr > th.warning:hover, .table-hover > tbody > tr.warning:hover > td, .table-hover > tbody > tr:hover > .warning, .table-hover > tbody > tr.warning:hover > th { - background-color: #ffd699; } - -.table > thead > tr > td.danger, -.table > thead > tr > th.danger, .table > thead > tr.danger > td, .table > thead > tr.danger > th, -.table > tbody > tr > td.danger, -.table > tbody > tr > th.danger, -.table > tbody > tr.danger > td, -.table > tbody > tr.danger > th, -.table > tfoot > tr > td.danger, -.table > tfoot > tr > th.danger, -.table > tfoot > tr.danger > td, -.table > tfoot > tr.danger > th { - background-color: #f9bdbb; } - -.table-hover > tbody > tr > td.danger:hover, -.table-hover > tbody > tr > th.danger:hover, .table-hover > tbody > tr.danger:hover > td, .table-hover > tbody > tr:hover > .danger, .table-hover > tbody > tr.danger:hover > th { - background-color: #f7a6a4; } - -.table-responsive { - overflow-x: auto; - min-height: 0.01%; } - @media screen and (max-width: 767px) { - .table-responsive { - width: 100%; - margin-bottom: 20.25px; - overflow-y: hidden; - -ms-overflow-style: -ms-autohiding-scrollbar; - border: 1px solid #ddd; } - .table-responsive > .table { - margin-bottom: 0; } - .table-responsive > .table > thead > tr > th, - .table-responsive > .table > thead > tr > td, - .table-responsive > .table > tbody > tr > th, - .table-responsive > .table > tbody > tr > td, - .table-responsive > .table > tfoot > tr > th, - .table-responsive > .table > tfoot > tr > td { - white-space: nowrap; } - .table-responsive > .table-bordered { - border: 0; } - .table-responsive > .table-bordered > thead > tr > th:first-child, - .table-responsive > .table-bordered > thead > tr > td:first-child, - .table-responsive > .table-bordered > tbody > tr > th:first-child, - .table-responsive > .table-bordered > tbody > tr > td:first-child, - .table-responsive > .table-bordered > tfoot > tr > th:first-child, - .table-responsive > .table-bordered > tfoot > tr > td:first-child { - border-left: 0; } - .table-responsive > .table-bordered > thead > tr > th:last-child, - .table-responsive > .table-bordered > thead > tr > td:last-child, - .table-responsive > .table-bordered > tbody > tr > th:last-child, - .table-responsive > .table-bordered > tbody > tr > td:last-child, - .table-responsive > .table-bordered > tfoot > tr > th:last-child, - .table-responsive > .table-bordered > tfoot > tr > td:last-child { - border-right: 0; } - .table-responsive > .table-bordered > tbody > tr:last-child > th, - .table-responsive > .table-bordered > tbody > tr:last-child > td, - .table-responsive > .table-bordered > tfoot > tr:last-child > th, - .table-responsive > .table-bordered > tfoot > tr:last-child > td { - border-bottom: 0; } } - -fieldset { - padding: 0; - margin: 0; - border: 0; - min-width: 0; } - -legend { - display: block; - width: 100%; - padding: 0; - margin-bottom: 27px; - font-size: 22.5px; - line-height: inherit; - color: #212121; - border: 0; - border-bottom: 1px solid #e5e5e5; } - -label { - display: inline-block; - max-width: 100%; - margin-bottom: 5px; - font-weight: bold; } - -input[type="search"] { - -webkit-box-sizing: border-box; - -moz-box-sizing: border-box; - box-sizing: border-box; } - -input[type="radio"], -input[type="checkbox"] { - margin: 4px 0 0; - margin-top: 1px \9; - line-height: normal; } - -input[type="file"] { - display: block; } - -input[type="range"] { - display: block; - width: 100%; } - -select[multiple], -select[size] { - height: auto; } - -input[type="file"]:focus, -input[type="radio"]:focus, -input[type="checkbox"]:focus { - outline: 5px auto -webkit-focus-ring-color; - outline-offset: -2px; } - -output { - display: block; - padding-top: 7px; - font-size: 15px; - line-height: 1.846; - color: #666; } - -.form-control { - display: block; - width: 100%; - height: 41px; - padding: 6px 16px; - font-size: 15px; - line-height: 1.846; - color: #666; - background-color: transparent; - background-image: none; - border: 1px solid transparent; - border-radius: 3px; - -webkit-box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075); - box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075); - -webkit-transition: border-color ease-in-out 0.15s, box-shadow ease-in-out 0.15s; - -o-transition: border-color ease-in-out 0.15s, box-shadow ease-in-out 0.15s; - transition: border-color ease-in-out 0.15s, box-shadow ease-in-out 0.15s; } - .form-control:focus { - border-color: #66afe9; - outline: 0; - -webkit-box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075), 0 0 8px rgba(102, 175, 233, 0.6); - box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075), 0 0 8px rgba(102, 175, 233, 0.6); } - .form-control::-moz-placeholder { - color: #bbb; - opacity: 1; } - .form-control:-ms-input-placeholder { - color: #bbb; } - .form-control::-webkit-input-placeholder { - color: #bbb; } - .form-control::-ms-expand { - border: 0; - background-color: transparent; } - .form-control[disabled], .form-control[readonly], fieldset[disabled] .form-control { - background-color: transparent; - opacity: 1; } - .form-control[disabled], fieldset[disabled] .form-control { - cursor: not-allowed; } - -textarea.form-control { - height: auto; } - -input[type="search"] { - -webkit-appearance: none; } - -@media screen and (-webkit-min-device-pixel-ratio: 0) { - input[type="date"].form-control, - input[type="time"].form-control, - input[type="datetime-local"].form-control, - input[type="month"].form-control { - line-height: 41px; } - input[type="date"].input-sm, .input-group-sm > input[type="date"].form-control, - .input-group-sm > input[type="date"].input-group-addon, - .input-group-sm > .input-group-btn > input[type="date"].btn, .input-group-sm input[type="date"], - input[type="time"].input-sm, - .input-group-sm > input[type="time"].form-control, - .input-group-sm > input[type="time"].input-group-addon, - .input-group-sm > .input-group-btn > input[type="time"].btn, .input-group-sm - input[type="time"], - input[type="datetime-local"].input-sm, - .input-group-sm > input[type="datetime-local"].form-control, - .input-group-sm > input[type="datetime-local"].input-group-addon, - .input-group-sm > .input-group-btn > input[type="datetime-local"].btn, .input-group-sm - input[type="datetime-local"], - input[type="month"].input-sm, - .input-group-sm > input[type="month"].form-control, - .input-group-sm > input[type="month"].input-group-addon, - .input-group-sm > .input-group-btn > input[type="month"].btn, .input-group-sm - input[type="month"] { - line-height: 31px; } - input[type="date"].input-lg, .input-group-lg > input[type="date"].form-control, - .input-group-lg > input[type="date"].input-group-addon, - .input-group-lg > .input-group-btn > input[type="date"].btn, .input-group-lg input[type="date"], - input[type="time"].input-lg, - .input-group-lg > input[type="time"].form-control, - .input-group-lg > input[type="time"].input-group-addon, - .input-group-lg > .input-group-btn > input[type="time"].btn, .input-group-lg - input[type="time"], - input[type="datetime-local"].input-lg, - .input-group-lg > input[type="datetime-local"].form-control, - .input-group-lg > input[type="datetime-local"].input-group-addon, - .input-group-lg > .input-group-btn > input[type="datetime-local"].btn, .input-group-lg - input[type="datetime-local"], - input[type="month"].input-lg, - .input-group-lg > input[type="month"].form-control, - .input-group-lg > input[type="month"].input-group-addon, - .input-group-lg > .input-group-btn > input[type="month"].btn, .input-group-lg - input[type="month"] { - line-height: 48px; } } -.form-group { - margin-bottom: 15px; } - -.radio, -.checkbox { - position: relative; - display: block; - margin-top: 10px; - margin-bottom: 10px; } - .radio label, - .checkbox label { - min-height: 27px; - padding-left: 20px; - margin-bottom: 0; - font-weight: normal; - cursor: pointer; } - -.radio input[type="radio"], -.radio-inline input[type="radio"], -.checkbox input[type="checkbox"], -.checkbox-inline input[type="checkbox"] { - position: absolute; - margin-left: -20px; - margin-top: 4px \9; } - -.radio + .radio, -.checkbox + .checkbox { - margin-top: -5px; } - -.radio-inline, -.checkbox-inline { - position: relative; - display: inline-block; - padding-left: 20px; - margin-bottom: 0; - vertical-align: middle; - font-weight: normal; - cursor: pointer; } - -.radio-inline + .radio-inline, -.checkbox-inline + .checkbox-inline { - margin-top: 0; - margin-left: 10px; } - -input[type="radio"][disabled], input[type="radio"].disabled, fieldset[disabled] input[type="radio"], -input[type="checkbox"][disabled], -input[type="checkbox"].disabled, fieldset[disabled] -input[type="checkbox"] { - cursor: not-allowed; } - -.radio-inline.disabled, fieldset[disabled] .radio-inline, -.checkbox-inline.disabled, fieldset[disabled] -.checkbox-inline { - cursor: not-allowed; } - -.radio.disabled label, fieldset[disabled] .radio label, -.checkbox.disabled label, fieldset[disabled] -.checkbox label { - cursor: not-allowed; } - -.form-control-static { - padding-top: 7px; - padding-bottom: 7px; - margin-bottom: 0; - min-height: 42px; } - .form-control-static.input-lg, .input-group-lg > .form-control-static.form-control, - .input-group-lg > .form-control-static.input-group-addon, - .input-group-lg > .input-group-btn > .form-control-static.btn, .form-control-static.input-sm, .input-group-sm > .form-control-static.form-control, - .input-group-sm > .form-control-static.input-group-addon, - .input-group-sm > .input-group-btn > .form-control-static.btn { - padding-left: 0; - padding-right: 0; } - -.input-sm, .input-group-sm > .form-control, -.input-group-sm > .input-group-addon, -.input-group-sm > .input-group-btn > .btn { - height: 31px; - padding: 5px 10px; - font-size: 13px; - line-height: 1.5; - border-radius: 3px; } - -select.input-sm, .input-group-sm > select.form-control, -.input-group-sm > select.input-group-addon, -.input-group-sm > .input-group-btn > select.btn { - height: 31px; - line-height: 31px; } - -textarea.input-sm, .input-group-sm > textarea.form-control, -.input-group-sm > textarea.input-group-addon, -.input-group-sm > .input-group-btn > textarea.btn, -select[multiple].input-sm, -.input-group-sm > select[multiple].form-control, -.input-group-sm > select[multiple].input-group-addon, -.input-group-sm > .input-group-btn > select[multiple].btn { - height: auto; } - -.form-group-sm .form-control { - height: 31px; - padding: 5px 10px; - font-size: 13px; - line-height: 1.5; - border-radius: 3px; } -.form-group-sm select.form-control { - height: 31px; - line-height: 31px; } -.form-group-sm textarea.form-control, -.form-group-sm select[multiple].form-control { - height: auto; } -.form-group-sm .form-control-static { - height: 31px; - min-height: 40px; - padding: 6px 10px; - font-size: 13px; - line-height: 1.5; } - -.input-lg, .input-group-lg > .form-control, -.input-group-lg > .input-group-addon, -.input-group-lg > .input-group-btn > .btn { - height: 48px; - padding: 10px 16px; - font-size: 19px; - line-height: 1.33333; - border-radius: 3px; } - -select.input-lg, .input-group-lg > select.form-control, -.input-group-lg > select.input-group-addon, -.input-group-lg > .input-group-btn > select.btn { - height: 48px; - line-height: 48px; } - -textarea.input-lg, .input-group-lg > textarea.form-control, -.input-group-lg > textarea.input-group-addon, -.input-group-lg > .input-group-btn > textarea.btn, -select[multiple].input-lg, -.input-group-lg > select[multiple].form-control, -.input-group-lg > select[multiple].input-group-addon, -.input-group-lg > .input-group-btn > select[multiple].btn { - height: auto; } - -.form-group-lg .form-control { - height: 48px; - padding: 10px 16px; - font-size: 19px; - line-height: 1.33333; - border-radius: 3px; } -.form-group-lg select.form-control { - height: 48px; - line-height: 48px; } -.form-group-lg textarea.form-control, -.form-group-lg select[multiple].form-control { - height: auto; } -.form-group-lg .form-control-static { - height: 48px; - min-height: 46px; - padding: 11px 16px; - font-size: 19px; - line-height: 1.33333; } - -.has-feedback { - position: relative; } - .has-feedback .form-control { - padding-right: 51.25px; } - -.form-control-feedback { - position: absolute; - top: 0; - right: 0; - z-index: 2; - display: block; - width: 41px; - height: 41px; - line-height: 41px; - text-align: center; - pointer-events: none; } - -.input-lg + .form-control-feedback, .input-group-lg > .form-control + .form-control-feedback, -.input-group-lg > .input-group-addon + .form-control-feedback, -.input-group-lg > .input-group-btn > .btn + .form-control-feedback, -.input-group-lg + .form-control-feedback, -.form-group-lg .form-control + .form-control-feedback { - width: 48px; - height: 48px; - line-height: 48px; } - -.input-sm + .form-control-feedback, .input-group-sm > .form-control + .form-control-feedback, -.input-group-sm > .input-group-addon + .form-control-feedback, -.input-group-sm > .input-group-btn > .btn + .form-control-feedback, -.input-group-sm + .form-control-feedback, -.form-group-sm .form-control + .form-control-feedback { - width: 31px; - height: 31px; - line-height: 31px; } - -.has-success .help-block, -.has-success .control-label, -.has-success .radio, -.has-success .checkbox, -.has-success .radio-inline, -.has-success .checkbox-inline, .has-success.radio label, .has-success.checkbox label, .has-success.radio-inline label, .has-success.checkbox-inline label { - color: #4CAF50; } -.has-success .form-control { - border-color: #4CAF50; - -webkit-box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075); - box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075); } - .has-success .form-control:focus { - border-color: #3d8b40; - -webkit-box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075), 0 0 6px #92cf94; - box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075), 0 0 6px #92cf94; } -.has-success .input-group-addon { - color: #4CAF50; - border-color: #4CAF50; - background-color: #dff0d8; } -.has-success .form-control-feedback { - color: #4CAF50; } - -.has-warning .help-block, -.has-warning .control-label, -.has-warning .radio, -.has-warning .checkbox, -.has-warning .radio-inline, -.has-warning .checkbox-inline, .has-warning.radio label, .has-warning.checkbox label, .has-warning.radio-inline label, .has-warning.checkbox-inline label { - color: #ff9800; } -.has-warning .form-control { - border-color: #ff9800; - -webkit-box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075); - box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075); } - .has-warning .form-control:focus { - border-color: #cc7a00; - -webkit-box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075), 0 0 6px #ffc166; - box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075), 0 0 6px #ffc166; } -.has-warning .input-group-addon { - color: #ff9800; - border-color: #ff9800; - background-color: #ffe0b2; } -.has-warning .form-control-feedback { - color: #ff9800; } - -.has-error .help-block, -.has-error .control-label, -.has-error .radio, -.has-error .checkbox, -.has-error .radio-inline, -.has-error .checkbox-inline, .has-error.radio label, .has-error.checkbox label, .has-error.radio-inline label, .has-error.checkbox-inline label { - color: #e51c23; } -.has-error .form-control { - border-color: #e51c23; - -webkit-box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075); - box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075); } - .has-error .form-control:focus { - border-color: #b9151b; - -webkit-box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075), 0 0 6px #ef787c; - box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.075), 0 0 6px #ef787c; } -.has-error .input-group-addon { - color: #e51c23; - border-color: #e51c23; - background-color: #f9bdbb; } -.has-error .form-control-feedback { - color: #e51c23; } - -.has-feedback label ~ .form-control-feedback { - top: 32px; } -.has-feedback label.sr-only ~ .form-control-feedback { - top: 0; } - -.help-block { - display: block; - margin-top: 5px; - margin-bottom: 10px; - color: #848484; } - -@media (min-width: 768px) { - .form-inline .form-group { - display: inline-block; - margin-bottom: 0; - vertical-align: middle; } - .form-inline .form-control { - display: inline-block; - width: auto; - vertical-align: middle; } - .form-inline .form-control-static { - display: inline-block; } - .form-inline .input-group { - display: inline-table; - vertical-align: middle; } - .form-inline .input-group .input-group-addon, - .form-inline .input-group .input-group-btn, - .form-inline .input-group .form-control { - width: auto; } - .form-inline .input-group > .form-control { - width: 100%; } - .form-inline .control-label { - margin-bottom: 0; - vertical-align: middle; } - .form-inline .radio, - .form-inline .checkbox { - display: inline-block; - margin-top: 0; - margin-bottom: 0; - vertical-align: middle; } - .form-inline .radio label, - .form-inline .checkbox label { - padding-left: 0; } - .form-inline .radio input[type="radio"], - .form-inline .checkbox input[type="checkbox"] { - position: relative; - margin-left: 0; } - .form-inline .has-feedback .form-control-feedback { - top: 0; } } - -.form-horizontal .radio, -.form-horizontal .checkbox, -.form-horizontal .radio-inline, -.form-horizontal .checkbox-inline { - margin-top: 0; - margin-bottom: 0; - padding-top: 7px; } -.form-horizontal .radio, -.form-horizontal .checkbox { - min-height: 34px; } -.form-horizontal .form-group { - margin-left: -15px; - margin-right: -15px; } - .form-horizontal .form-group:before, .form-horizontal .form-group:after { - content: " "; - display: table; } - .form-horizontal .form-group:after { - clear: both; } -@media (min-width: 768px) { - .form-horizontal .control-label { - text-align: right; - margin-bottom: 0; - padding-top: 7px; } } -.form-horizontal .has-feedback .form-control-feedback { - right: 15px; } -@media (min-width: 768px) { - .form-horizontal .form-group-lg .control-label { - padding-top: 11px; - font-size: 19px; } } -@media (min-width: 768px) { - .form-horizontal .form-group-sm .control-label { - padding-top: 6px; - font-size: 13px; } } - -.btn { - display: inline-block; - margin-bottom: 0; - font-weight: normal; - text-align: center; - vertical-align: middle; - touch-action: manipulation; - cursor: pointer; - background-image: none; - border: 1px solid transparent; - white-space: nowrap; - padding: 6px 16px; - font-size: 15px; - line-height: 1.846; - border-radius: 3px; - -webkit-user-select: none; - -moz-user-select: none; - -ms-user-select: none; - user-select: none; } - .btn:focus, .btn.focus, .btn:active:focus, .btn:active.focus, .btn.active:focus, .btn.active.focus { - outline: 5px auto -webkit-focus-ring-color; - outline-offset: -2px; } - .btn:hover, .btn:focus, .btn.focus { - color: #444; - text-decoration: none; } - .btn:active, .btn.active { - outline: 0; - background-image: none; - -webkit-box-shadow: inset 0 3px 5px rgba(0, 0, 0, 0.125); - box-shadow: inset 0 3px 5px rgba(0, 0, 0, 0.125); } - .btn.disabled, .btn[disabled], fieldset[disabled] .btn { - cursor: not-allowed; - opacity: 0.65; - filter: alpha(opacity=65); - -webkit-box-shadow: none; - box-shadow: none; } - -a.btn.disabled, fieldset[disabled] a.btn { - pointer-events: none; } - -.btn-default { - color: #444; - background-color: #fff; - border-color: transparent; } - .btn-default:focus, .btn-default.focus { - color: #444; - background-color: #e6e6e6; - border-color: transparent; } - .btn-default:hover { - color: #444; - background-color: #e6e6e6; - border-color: transparent; } - .btn-default:active, .btn-default.active, .open > .btn-default.dropdown-toggle { - color: #444; - background-color: #e6e6e6; - border-color: transparent; } - .btn-default:active:hover, .btn-default:active:focus, .btn-default:active.focus, .btn-default.active:hover, .btn-default.active:focus, .btn-default.active.focus, .open > .btn-default.dropdown-toggle:hover, .open > .btn-default.dropdown-toggle:focus, .open > .btn-default.dropdown-toggle.focus { - color: #444; - background-color: #d4d4d4; - border-color: transparent; } - .btn-default:active, .btn-default.active, .open > .btn-default.dropdown-toggle { - background-image: none; } - .btn-default.disabled:hover, .btn-default.disabled:focus, .btn-default.disabled.focus, .btn-default[disabled]:hover, .btn-default[disabled]:focus, .btn-default[disabled].focus, fieldset[disabled] .btn-default:hover, fieldset[disabled] .btn-default:focus, fieldset[disabled] .btn-default.focus { - background-color: #fff; - border-color: transparent; } - .btn-default .badge { - color: #fff; - background-color: #444; } - -.btn-primary { - color: #fff; - background-color: #5a9ddb; - border-color: transparent; } - .btn-primary:focus, .btn-primary.focus { - color: #fff; - background-color: #3084d2; - border-color: transparent; } - .btn-primary:hover { - color: #fff; - background-color: #3084d2; - border-color: transparent; } - .btn-primary:active, .btn-primary.active, .open > .btn-primary.dropdown-toggle { - color: #fff; - background-color: #3084d2; - border-color: transparent; } - .btn-primary:active:hover, .btn-primary:active:focus, .btn-primary:active.focus, .btn-primary.active:hover, .btn-primary.active:focus, .btn-primary.active.focus, .open > .btn-primary.dropdown-toggle:hover, .open > .btn-primary.dropdown-toggle:focus, .open > .btn-primary.dropdown-toggle.focus { - color: #fff; - background-color: #2872b6; - border-color: transparent; } - .btn-primary:active, .btn-primary.active, .open > .btn-primary.dropdown-toggle { - background-image: none; } - .btn-primary.disabled:hover, .btn-primary.disabled:focus, .btn-primary.disabled.focus, .btn-primary[disabled]:hover, .btn-primary[disabled]:focus, .btn-primary[disabled].focus, fieldset[disabled] .btn-primary:hover, fieldset[disabled] .btn-primary:focus, fieldset[disabled] .btn-primary.focus { - background-color: #5a9ddb; - border-color: transparent; } - .btn-primary .badge { - color: #5a9ddb; - background-color: #fff; } - -.btn-success { - color: #fff; - background-color: #4CAF50; - border-color: transparent; } - .btn-success:focus, .btn-success.focus { - color: #fff; - background-color: #3d8b40; - border-color: transparent; } - .btn-success:hover { - color: #fff; - background-color: #3d8b40; - border-color: transparent; } - .btn-success:active, .btn-success.active, .open > .btn-success.dropdown-toggle { - color: #fff; - background-color: #3d8b40; - border-color: transparent; } - .btn-success:active:hover, .btn-success:active:focus, .btn-success:active.focus, .btn-success.active:hover, .btn-success.active:focus, .btn-success.active.focus, .open > .btn-success.dropdown-toggle:hover, .open > .btn-success.dropdown-toggle:focus, .open > .btn-success.dropdown-toggle.focus { - color: #fff; - background-color: #327334; - border-color: transparent; } - .btn-success:active, .btn-success.active, .open > .btn-success.dropdown-toggle { - background-image: none; } - .btn-success.disabled:hover, .btn-success.disabled:focus, .btn-success.disabled.focus, .btn-success[disabled]:hover, .btn-success[disabled]:focus, .btn-success[disabled].focus, fieldset[disabled] .btn-success:hover, fieldset[disabled] .btn-success:focus, fieldset[disabled] .btn-success.focus { - background-color: #4CAF50; - border-color: transparent; } - .btn-success .badge { - color: #4CAF50; - background-color: #fff; } - -.btn-info { - color: #fff; - background-color: #9C27B0; - border-color: transparent; } - .btn-info:focus, .btn-info.focus { - color: #fff; - background-color: #771e86; - border-color: transparent; } - .btn-info:hover { - color: #fff; - background-color: #771e86; - border-color: transparent; } - .btn-info:active, .btn-info.active, .open > .btn-info.dropdown-toggle { - color: #fff; - background-color: #771e86; - border-color: transparent; } - .btn-info:active:hover, .btn-info:active:focus, .btn-info:active.focus, .btn-info.active:hover, .btn-info.active:focus, .btn-info.active.focus, .open > .btn-info.dropdown-toggle:hover, .open > .btn-info.dropdown-toggle:focus, .open > .btn-info.dropdown-toggle.focus { - color: #fff; - background-color: #5d1769; - border-color: transparent; } - .btn-info:active, .btn-info.active, .open > .btn-info.dropdown-toggle { - background-image: none; } - .btn-info.disabled:hover, .btn-info.disabled:focus, .btn-info.disabled.focus, .btn-info[disabled]:hover, .btn-info[disabled]:focus, .btn-info[disabled].focus, fieldset[disabled] .btn-info:hover, fieldset[disabled] .btn-info:focus, fieldset[disabled] .btn-info.focus { - background-color: #9C27B0; - border-color: transparent; } - .btn-info .badge { - color: #9C27B0; - background-color: #fff; } - -.btn-warning { - color: #fff; - background-color: #ff9800; - border-color: transparent; } - .btn-warning:focus, .btn-warning.focus { - color: #fff; - background-color: #cc7a00; - border-color: transparent; } - .btn-warning:hover { - color: #fff; - background-color: #cc7a00; - border-color: transparent; } - .btn-warning:active, .btn-warning.active, .open > .btn-warning.dropdown-toggle { - color: #fff; - background-color: #cc7a00; - border-color: transparent; } - .btn-warning:active:hover, .btn-warning:active:focus, .btn-warning:active.focus, .btn-warning.active:hover, .btn-warning.active:focus, .btn-warning.active.focus, .open > .btn-warning.dropdown-toggle:hover, .open > .btn-warning.dropdown-toggle:focus, .open > .btn-warning.dropdown-toggle.focus { - color: #fff; - background-color: #a86400; - border-color: transparent; } - .btn-warning:active, .btn-warning.active, .open > .btn-warning.dropdown-toggle { - background-image: none; } - .btn-warning.disabled:hover, .btn-warning.disabled:focus, .btn-warning.disabled.focus, .btn-warning[disabled]:hover, .btn-warning[disabled]:focus, .btn-warning[disabled].focus, fieldset[disabled] .btn-warning:hover, fieldset[disabled] .btn-warning:focus, fieldset[disabled] .btn-warning.focus { - background-color: #ff9800; - border-color: transparent; } - .btn-warning .badge { - color: #ff9800; - background-color: #fff; } - -.btn-danger { - color: #fff; - background-color: #e51c23; - border-color: transparent; } - .btn-danger:focus, .btn-danger.focus { - color: #fff; - background-color: #b9151b; - border-color: transparent; } - .btn-danger:hover { - color: #fff; - background-color: #b9151b; - border-color: transparent; } - .btn-danger:active, .btn-danger.active, .open > .btn-danger.dropdown-toggle { - color: #fff; - background-color: #b9151b; - border-color: transparent; } - .btn-danger:active:hover, .btn-danger:active:focus, .btn-danger:active.focus, .btn-danger.active:hover, .btn-danger.active:focus, .btn-danger.active.focus, .open > .btn-danger.dropdown-toggle:hover, .open > .btn-danger.dropdown-toggle:focus, .open > .btn-danger.dropdown-toggle.focus { - color: #fff; - background-color: #991216; - border-color: transparent; } - .btn-danger:active, .btn-danger.active, .open > .btn-danger.dropdown-toggle { - background-image: none; } - .btn-danger.disabled:hover, .btn-danger.disabled:focus, .btn-danger.disabled.focus, .btn-danger[disabled]:hover, .btn-danger[disabled]:focus, .btn-danger[disabled].focus, fieldset[disabled] .btn-danger:hover, fieldset[disabled] .btn-danger:focus, fieldset[disabled] .btn-danger.focus { - background-color: #e51c23; - border-color: transparent; } - .btn-danger .badge { - color: #e51c23; - background-color: #fff; } - -.btn-link { - color: #5a9ddb; - font-weight: normal; - border-radius: 0; } - .btn-link, .btn-link:active, .btn-link.active, .btn-link[disabled], fieldset[disabled] .btn-link { - background-color: transparent; - -webkit-box-shadow: none; - box-shadow: none; } - .btn-link, .btn-link:hover, .btn-link:focus, .btn-link:active { - border-color: transparent; } - .btn-link:hover, .btn-link:focus { - color: #2a77bf; - text-decoration: underline; - background-color: transparent; } - .btn-link[disabled]:hover, .btn-link[disabled]:focus, fieldset[disabled] .btn-link:hover, fieldset[disabled] .btn-link:focus { - color: #bbb; - text-decoration: none; } - -.btn-lg, .btn-group-lg > .btn { - padding: 10px 16px; - font-size: 19px; - line-height: 1.33333; - border-radius: 3px; } - -.btn-sm, .btn-group-sm > .btn { - padding: 5px 10px; - font-size: 13px; - line-height: 1.5; - border-radius: 3px; } - -.btn-xs, .btn-group-xs > .btn { - padding: 1px 5px; - font-size: 13px; - line-height: 1.5; - border-radius: 3px; } - -.btn-block { - display: block; - width: 100%; } - -.btn-block + .btn-block { - margin-top: 5px; } - -input[type="submit"].btn-block, -input[type="reset"].btn-block, -input[type="button"].btn-block { - width: 100%; } - -.fade { - opacity: 0; - -webkit-transition: opacity 0.15s linear; - -o-transition: opacity 0.15s linear; - transition: opacity 0.15s linear; } - .fade.in { - opacity: 1; } - -.collapse { - display: none; } - .collapse.in { - display: block; } - -tr.collapse.in { - display: table-row; } - -tbody.collapse.in { - display: table-row-group; } - -.collapsing { - position: relative; - height: 0; - overflow: hidden; - -webkit-transition-property: height, visibility; - transition-property: height, visibility; - -webkit-transition-duration: 0.35s; - transition-duration: 0.35s; - -webkit-transition-timing-function: ease; - transition-timing-function: ease; } - -.caret { - display: inline-block; - width: 0; - height: 0; - margin-left: 2px; - vertical-align: middle; - border-top: 4px dashed; - border-top: 4px solid \9; - border-right: 4px solid transparent; - border-left: 4px solid transparent; } - -.dropup, -.dropdown { - position: relative; } - -.dropdown-toggle:focus { - outline: 0; } - -.dropdown-menu { - position: absolute; - top: 100%; - left: 0; - z-index: 1000; - display: none; - float: left; - min-width: 160px; - padding: 5px 0; - margin: 2px 0 0; - list-style: none; - font-size: 15px; - text-align: left; - background-color: #fff; - border: 1px solid #ccc; - border: 1px solid rgba(0, 0, 0, 0.15); - border-radius: 3px; - -webkit-box-shadow: 0 6px 12px rgba(0, 0, 0, 0.175); - box-shadow: 0 6px 12px rgba(0, 0, 0, 0.175); - background-clip: padding-box; } - .dropdown-menu.pull-right { - right: 0; - left: auto; } - .dropdown-menu .divider { - height: 1px; - margin: 12.5px 0; - overflow: hidden; - background-color: #e5e5e5; } - .dropdown-menu > li > a { - display: block; - padding: 3px 20px; - clear: both; - font-weight: normal; - line-height: 1.846; - color: #444; - white-space: nowrap; } - -.dropdown-menu > li > a:hover, .dropdown-menu > li > a:focus { - text-decoration: none; - color: #141414; - background-color: #eeeeee; } - -.dropdown-menu > .active > a, .dropdown-menu > .active > a:hover, .dropdown-menu > .active > a:focus { - color: #fff; - text-decoration: none; - outline: 0; - background-color: #5a9ddb; } - -.dropdown-menu > .disabled > a, .dropdown-menu > .disabled > a:hover, .dropdown-menu > .disabled > a:focus { - color: #bbb; } -.dropdown-menu > .disabled > a:hover, .dropdown-menu > .disabled > a:focus { - text-decoration: none; - background-color: transparent; - background-image: none; - filter: progid:DXImageTransform.Microsoft.gradient(enabled = false); - cursor: not-allowed; } - -.open > .dropdown-menu { - display: block; } -.open > a { - outline: 0; } - -.dropdown-menu-right { - left: auto; - right: 0; } - -.dropdown-menu-left { - left: 0; - right: auto; } - -.dropdown-header { - display: block; - padding: 3px 20px; - font-size: 13px; - line-height: 1.846; - color: #bbb; - white-space: nowrap; } - -.dropdown-backdrop { - position: fixed; - left: 0; - right: 0; - bottom: 0; - top: 0; - z-index: 990; } - -.pull-right > .dropdown-menu { - right: 0; - left: auto; } - -.dropup .caret, -.navbar-fixed-bottom .dropdown .caret { - border-top: 0; - border-bottom: 4px dashed; - border-bottom: 4px solid \9; - content: ""; } -.dropup .dropdown-menu, -.navbar-fixed-bottom .dropdown .dropdown-menu { - top: auto; - bottom: 100%; - margin-bottom: 2px; } - -@media (min-width: 768px) { - .navbar-right .dropdown-menu { - right: 0; - left: auto; } - .navbar-right .dropdown-menu-left { - left: 0; - right: auto; } } -.btn-group, -.btn-group-vertical { - position: relative; - display: inline-block; - vertical-align: middle; } - .btn-group > .btn, - .btn-group-vertical > .btn { - position: relative; - float: left; } - .btn-group > .btn:hover, .btn-group > .btn:focus, .btn-group > .btn:active, .btn-group > .btn.active, - .btn-group-vertical > .btn:hover, - .btn-group-vertical > .btn:focus, - .btn-group-vertical > .btn:active, - .btn-group-vertical > .btn.active { - z-index: 2; } - -.btn-group .btn + .btn, -.btn-group .btn + .btn-group, -.btn-group .btn-group + .btn, -.btn-group .btn-group + .btn-group { - margin-left: -1px; } - -.btn-toolbar { - margin-left: -5px; } - .btn-toolbar:before, .btn-toolbar:after { - content: " "; - display: table; } - .btn-toolbar:after { - clear: both; } - .btn-toolbar .btn, - .btn-toolbar .btn-group, - .btn-toolbar .input-group { - float: left; } - .btn-toolbar > .btn, - .btn-toolbar > .btn-group, - .btn-toolbar > .input-group { - margin-left: 5px; } - -.btn-group > .btn:not(:first-child):not(:last-child):not(.dropdown-toggle) { - border-radius: 0; } - -.btn-group > .btn:first-child { - margin-left: 0; } - .btn-group > .btn:first-child:not(:last-child):not(.dropdown-toggle) { - border-bottom-right-radius: 0; - border-top-right-radius: 0; } - -.btn-group > .btn:last-child:not(:first-child), -.btn-group > .dropdown-toggle:not(:first-child) { - border-bottom-left-radius: 0; - border-top-left-radius: 0; } - -.btn-group > .btn-group { - float: left; } - -.btn-group > .btn-group:not(:first-child):not(:last-child) > .btn { - border-radius: 0; } - -.btn-group > .btn-group:first-child:not(:last-child) > .btn:last-child, -.btn-group > .btn-group:first-child:not(:last-child) > .dropdown-toggle { - border-bottom-right-radius: 0; - border-top-right-radius: 0; } - -.btn-group > .btn-group:last-child:not(:first-child) > .btn:first-child { - border-bottom-left-radius: 0; - border-top-left-radius: 0; } - -.btn-group .dropdown-toggle:active, -.btn-group.open .dropdown-toggle { - outline: 0; } - -.btn-group > .btn + .dropdown-toggle { - padding-left: 8px; - padding-right: 8px; } - -.btn-group > .btn-lg + .dropdown-toggle, .btn-group-lg.btn-group > .btn + .dropdown-toggle { - padding-left: 12px; - padding-right: 12px; } - -.btn-group.open .dropdown-toggle { - -webkit-box-shadow: inset 0 3px 5px rgba(0, 0, 0, 0.125); - box-shadow: inset 0 3px 5px rgba(0, 0, 0, 0.125); } - .btn-group.open .dropdown-toggle.btn-link { - -webkit-box-shadow: none; - box-shadow: none; } - -.btn .caret { - margin-left: 0; } - -.btn-lg .caret, .btn-group-lg > .btn .caret { - border-width: 5px 5px 0; - border-bottom-width: 0; } - -.dropup .btn-lg .caret, .dropup .btn-group-lg > .btn .caret { - border-width: 0 5px 5px; } - -.btn-group-vertical > .btn, -.btn-group-vertical > .btn-group, -.btn-group-vertical > .btn-group > .btn { - display: block; - float: none; - width: 100%; - max-width: 100%; } -.btn-group-vertical > .btn-group:before, .btn-group-vertical > .btn-group:after { - content: " "; - display: table; } -.btn-group-vertical > .btn-group:after { - clear: both; } -.btn-group-vertical > .btn-group > .btn { - float: none; } -.btn-group-vertical > .btn + .btn, -.btn-group-vertical > .btn + .btn-group, -.btn-group-vertical > .btn-group + .btn, -.btn-group-vertical > .btn-group + .btn-group { - margin-top: -1px; - margin-left: 0; } - -.btn-group-vertical > .btn:not(:first-child):not(:last-child) { - border-radius: 0; } -.btn-group-vertical > .btn:first-child:not(:last-child) { - border-top-right-radius: 3px; - border-top-left-radius: 3px; - border-bottom-right-radius: 0; - border-bottom-left-radius: 0; } -.btn-group-vertical > .btn:last-child:not(:first-child) { - border-top-right-radius: 0; - border-top-left-radius: 0; - border-bottom-right-radius: 3px; - border-bottom-left-radius: 3px; } - -.btn-group-vertical > .btn-group:not(:first-child):not(:last-child) > .btn { - border-radius: 0; } - -.btn-group-vertical > .btn-group:first-child:not(:last-child) > .btn:last-child, -.btn-group-vertical > .btn-group:first-child:not(:last-child) > .dropdown-toggle { - border-bottom-right-radius: 0; - border-bottom-left-radius: 0; } - -.btn-group-vertical > .btn-group:last-child:not(:first-child) > .btn:first-child { - border-top-right-radius: 0; - border-top-left-radius: 0; } - -.btn-group-justified { - display: table; - width: 100%; - table-layout: fixed; - border-collapse: separate; } - .btn-group-justified > .btn, - .btn-group-justified > .btn-group { - float: none; - display: table-cell; - width: 1%; } - .btn-group-justified > .btn-group .btn { - width: 100%; } - .btn-group-justified > .btn-group .dropdown-menu { - left: auto; } - -[data-toggle="buttons"] > .btn input[type="radio"], -[data-toggle="buttons"] > .btn input[type="checkbox"], -[data-toggle="buttons"] > .btn-group > .btn input[type="radio"], -[data-toggle="buttons"] > .btn-group > .btn input[type="checkbox"] { - position: absolute; - clip: rect(0, 0, 0, 0); - pointer-events: none; } - -.input-group { - position: relative; - display: table; - border-collapse: separate; } - .input-group[class*="col-"] { - float: none; - padding-left: 0; - padding-right: 0; } - .input-group .form-control { - position: relative; - z-index: 2; - float: left; - width: 100%; - margin-bottom: 0; } - .input-group .form-control:focus { - z-index: 3; } - -.input-group-addon, -.input-group-btn, -.input-group .form-control { - display: table-cell; } - .input-group-addon:not(:first-child):not(:last-child), - .input-group-btn:not(:first-child):not(:last-child), - .input-group .form-control:not(:first-child):not(:last-child) { - border-radius: 0; } - -.input-group-addon, -.input-group-btn { - width: 1%; - white-space: nowrap; - vertical-align: middle; } - -.input-group-addon { - padding: 6px 16px; - font-size: 15px; - font-weight: normal; - line-height: 1; - color: #666; - text-align: center; - background-color: transparent; - border: 1px solid transparent; - border-radius: 3px; } - .input-group-addon.input-sm, - .input-group-sm > .input-group-addon, - .input-group-sm > .input-group-btn > .input-group-addon.btn { - padding: 5px 10px; - font-size: 13px; - border-radius: 3px; } - .input-group-addon.input-lg, - .input-group-lg > .input-group-addon, - .input-group-lg > .input-group-btn > .input-group-addon.btn { - padding: 10px 16px; - font-size: 19px; - border-radius: 3px; } - .input-group-addon input[type="radio"], - .input-group-addon input[type="checkbox"] { - margin-top: 0; } - -.input-group .form-control:first-child, -.input-group-addon:first-child, -.input-group-btn:first-child > .btn, -.input-group-btn:first-child > .btn-group > .btn, -.input-group-btn:first-child > .dropdown-toggle, -.input-group-btn:last-child > .btn:not(:last-child):not(.dropdown-toggle), -.input-group-btn:last-child > .btn-group:not(:last-child) > .btn { - border-bottom-right-radius: 0; - border-top-right-radius: 0; } - -.input-group-addon:first-child { - border-right: 0; } - -.input-group .form-control:last-child, -.input-group-addon:last-child, -.input-group-btn:last-child > .btn, -.input-group-btn:last-child > .btn-group > .btn, -.input-group-btn:last-child > .dropdown-toggle, -.input-group-btn:first-child > .btn:not(:first-child), -.input-group-btn:first-child > .btn-group:not(:first-child) > .btn { - border-bottom-left-radius: 0; - border-top-left-radius: 0; } - -.input-group-addon:last-child { - border-left: 0; } - -.input-group-btn { - position: relative; - font-size: 0; - white-space: nowrap; } - .input-group-btn > .btn { - position: relative; } - .input-group-btn > .btn + .btn { - margin-left: -1px; } - .input-group-btn > .btn:hover, .input-group-btn > .btn:focus, .input-group-btn > .btn:active { - z-index: 2; } - .input-group-btn:first-child > .btn, - .input-group-btn:first-child > .btn-group { - margin-right: -1px; } - .input-group-btn:last-child > .btn, - .input-group-btn:last-child > .btn-group { - z-index: 2; - margin-left: -1px; } - -.nav { - margin-bottom: 0; - padding-left: 0; - list-style: none; } - .nav:before, .nav:after { - content: " "; - display: table; } - .nav:after { - clear: both; } - .nav > li { - position: relative; - display: block; } - .nav > li > a { - position: relative; - display: block; - padding: 10px 15px; } - .nav > li > a:hover, .nav > li > a:focus { - text-decoration: none; - background-color: #eeeeee; } - .nav > li.disabled > a { - color: #bbb; } - .nav > li.disabled > a:hover, .nav > li.disabled > a:focus { - color: #bbb; - text-decoration: none; - background-color: transparent; - cursor: not-allowed; } - .nav .open > a, .nav .open > a:hover, .nav .open > a:focus { - background-color: #eeeeee; - border-color: #5a9ddb; } - .nav .nav-divider { - height: 1px; - margin: 12.5px 0; - overflow: hidden; - background-color: #e5e5e5; } - .nav > li > a > img { - max-width: none; } - -.nav-tabs { - border-bottom: 1px solid transparent; } - .nav-tabs > li { - float: left; - margin-bottom: -1px; } - .nav-tabs > li > a { - margin-right: 2px; - line-height: 1.846; - border: 1px solid transparent; - border-radius: 3px 3px 0 0; } - .nav-tabs > li > a:hover { - border-color: #eeeeee #eeeeee transparent; } - .nav-tabs > li.active > a, .nav-tabs > li.active > a:hover, .nav-tabs > li.active > a:focus { - color: #666; - background-color: transparent; - border: 1px solid transparent; - border-bottom-color: transparent; - cursor: default; } - -.nav-pills > li { - float: left; } - .nav-pills > li > a { - border-radius: 3px; } - .nav-pills > li + li { - margin-left: 2px; } - .nav-pills > li.active > a, .nav-pills > li.active > a:hover, .nav-pills > li.active > a:focus { - color: #fff; - background-color: #5a9ddb; } - -.nav-stacked > li { - float: none; } - .nav-stacked > li + li { - margin-top: 2px; - margin-left: 0; } - -.nav-justified, .nav-tabs.nav-justified { - width: 100%; } - .nav-justified > li, .nav-tabs.nav-justified > li { - float: none; } - .nav-justified > li > a, .nav-tabs.nav-justified > li > a { - text-align: center; - margin-bottom: 5px; } - .nav-justified > .dropdown .dropdown-menu { - top: auto; - left: auto; } - @media (min-width: 768px) { - .nav-justified > li, .nav-tabs.nav-justified > li { - display: table-cell; - width: 1%; } - .nav-justified > li > a, .nav-tabs.nav-justified > li > a { - margin-bottom: 0; } } - -.nav-tabs-justified, .nav-tabs.nav-justified { - border-bottom: 0; } - .nav-tabs-justified > li > a, .nav-tabs.nav-justified > li > a { - margin-right: 0; - border-radius: 3px; } - .nav-tabs-justified > .active > a, .nav-tabs.nav-justified > .active > a, - .nav-tabs-justified > .active > a:hover, - .nav-tabs.nav-justified > .active > a:hover, - .nav-tabs-justified > .active > a:focus, - .nav-tabs.nav-justified > .active > a:focus { - border: 1px solid transparent; } - @media (min-width: 768px) { - .nav-tabs-justified > li > a, .nav-tabs.nav-justified > li > a { - border-bottom: 1px solid transparent; - border-radius: 3px 3px 0 0; } - .nav-tabs-justified > .active > a, .nav-tabs.nav-justified > .active > a, - .nav-tabs-justified > .active > a:hover, - .nav-tabs.nav-justified > .active > a:hover, - .nav-tabs-justified > .active > a:focus, - .nav-tabs.nav-justified > .active > a:focus { - border-bottom-color: #fff; } } - -.tab-content > .tab-pane { - display: none; } -.tab-content > .active { - display: block; } - -.nav-tabs .dropdown-menu { - margin-top: -1px; - border-top-right-radius: 0; - border-top-left-radius: 0; } - -.navbar { - position: relative; - min-height: 110px; - margin-bottom: 27px; - border: 1px solid transparent; } - .navbar:before, .navbar:after { - content: " "; - display: table; } - .navbar:after { - clear: both; } - @media (min-width: 768px) { - .navbar { - border-radius: 3px; } } - -.navbar-header:before, .navbar-header:after { - content: " "; - display: table; } -.navbar-header:after { - clear: both; } -@media (min-width: 768px) { - .navbar-header { - float: left; } } - -.navbar-collapse { - overflow-x: visible; - padding-right: 15px; - padding-left: 15px; - border-top: 1px solid transparent; - box-shadow: inset 0 1px 0 rgba(255, 255, 255, 0.1); - -webkit-overflow-scrolling: touch; } - .navbar-collapse:before, .navbar-collapse:after { - content: " "; - display: table; } - .navbar-collapse:after { - clear: both; } - .navbar-collapse.in { - overflow-y: auto; } - @media (min-width: 768px) { - .navbar-collapse { - width: auto; - border-top: 0; - box-shadow: none; } - .navbar-collapse.collapse { - display: block !important; - height: auto !important; - padding-bottom: 0; - overflow: visible !important; } - .navbar-collapse.in { - overflow-y: visible; } - .navbar-fixed-top .navbar-collapse, .navbar-static-top .navbar-collapse, .navbar-fixed-bottom .navbar-collapse { - padding-left: 0; - padding-right: 0; } } - -.navbar-fixed-top .navbar-collapse, -.navbar-fixed-bottom .navbar-collapse { - max-height: 340px; } - @media (max-device-width: 480px) and (orientation: landscape) { - .navbar-fixed-top .navbar-collapse, - .navbar-fixed-bottom .navbar-collapse { - max-height: 200px; } } - -.container > .navbar-header, -.container > .navbar-collapse, -.container-fluid > .navbar-header, -.container-fluid > .navbar-collapse { - margin-right: -15px; - margin-left: -15px; } - @media (min-width: 768px) { - .container > .navbar-header, - .container > .navbar-collapse, - .container-fluid > .navbar-header, - .container-fluid > .navbar-collapse { - margin-right: 0; - margin-left: 0; } } - -.navbar-static-top { - z-index: 1000; - border-width: 0 0 1px; } - @media (min-width: 768px) { - .navbar-static-top { - border-radius: 0; } } - -.navbar-fixed-top, -.navbar-fixed-bottom { - position: fixed; - right: 0; - left: 0; - z-index: 1030; } - @media (min-width: 768px) { - .navbar-fixed-top, - .navbar-fixed-bottom { - border-radius: 0; } } - -.navbar-fixed-top { - top: 0; - border-width: 0 0 1px; } - -.navbar-fixed-bottom { - bottom: 0; - margin-bottom: 0; - border-width: 1px 0 0; } - -.navbar-brand { - float: left; - padding: 41.5px 15px; - font-size: 19px; - line-height: 27px; - height: 110px; } - .navbar-brand:hover, .navbar-brand:focus { - text-decoration: none; } - .navbar-brand > img { - display: block; } - @media (min-width: 768px) { - .navbar > .container .navbar-brand, .navbar > .container-fluid .navbar-brand { - margin-left: -15px; } } - -.navbar-toggle { - position: relative; - float: right; - margin-right: 15px; - padding: 9px 10px; - margin-top: 38px; - margin-bottom: 38px; - background-color: transparent; - background-image: none; - border: 1px solid transparent; - border-radius: 3px; } - .navbar-toggle:focus { - outline: 0; } - .navbar-toggle .icon-bar { - display: block; - width: 22px; - height: 2px; - border-radius: 1px; } - .navbar-toggle .icon-bar + .icon-bar { - margin-top: 4px; } - @media (min-width: 768px) { - .navbar-toggle { - display: none; } } - -.navbar-nav { - margin: 20.75px -15px; } - .navbar-nav > li > a { - padding-top: 10px; - padding-bottom: 10px; - line-height: 27px; } - @media (max-width: 767px) { - .navbar-nav .open .dropdown-menu { - position: static; - float: none; - width: auto; - margin-top: 0; - background-color: transparent; - border: 0; - box-shadow: none; } - .navbar-nav .open .dropdown-menu > li > a, - .navbar-nav .open .dropdown-menu .dropdown-header { - padding: 5px 15px 5px 25px; } - .navbar-nav .open .dropdown-menu > li > a { - line-height: 27px; } - .navbar-nav .open .dropdown-menu > li > a:hover, .navbar-nav .open .dropdown-menu > li > a:focus { - background-image: none; } } - @media (min-width: 768px) { - .navbar-nav { - float: left; - margin: 0; } - .navbar-nav > li { - float: left; } - .navbar-nav > li > a { - padding-top: 41.5px; - padding-bottom: 41.5px; } } - -.navbar-form { - margin-left: -15px; - margin-right: -15px; - padding: 10px 15px; - border-top: 1px solid transparent; - border-bottom: 1px solid transparent; - -webkit-box-shadow: inset 0 1px 0 rgba(255, 255, 255, 0.1), 0 1px 0 rgba(255, 255, 255, 0.1); - box-shadow: inset 0 1px 0 rgba(255, 255, 255, 0.1), 0 1px 0 rgba(255, 255, 255, 0.1); - margin-top: 34.5px; - margin-bottom: 34.5px; } - @media (min-width: 768px) { - .navbar-form .form-group { - display: inline-block; - margin-bottom: 0; - vertical-align: middle; } - .navbar-form .form-control { - display: inline-block; - width: auto; - vertical-align: middle; } - .navbar-form .form-control-static { - display: inline-block; } - .navbar-form .input-group { - display: inline-table; - vertical-align: middle; } - .navbar-form .input-group .input-group-addon, - .navbar-form .input-group .input-group-btn, - .navbar-form .input-group .form-control { - width: auto; } - .navbar-form .input-group > .form-control { - width: 100%; } - .navbar-form .control-label { - margin-bottom: 0; - vertical-align: middle; } - .navbar-form .radio, - .navbar-form .checkbox { - display: inline-block; - margin-top: 0; - margin-bottom: 0; - vertical-align: middle; } - .navbar-form .radio label, - .navbar-form .checkbox label { - padding-left: 0; } - .navbar-form .radio input[type="radio"], - .navbar-form .checkbox input[type="checkbox"] { - position: relative; - margin-left: 0; } - .navbar-form .has-feedback .form-control-feedback { - top: 0; } } - @media (max-width: 767px) { - .navbar-form .form-group { - margin-bottom: 5px; } - .navbar-form .form-group:last-child { - margin-bottom: 0; } } - @media (min-width: 768px) { - .navbar-form { - width: auto; - border: 0; - margin-left: 0; - margin-right: 0; - padding-top: 0; - padding-bottom: 0; - -webkit-box-shadow: none; - box-shadow: none; } } - -.navbar-nav > li > .dropdown-menu { - margin-top: 0; - border-top-right-radius: 0; - border-top-left-radius: 0; } - -.navbar-fixed-bottom .navbar-nav > li > .dropdown-menu { - margin-bottom: 0; - border-top-right-radius: 3px; - border-top-left-radius: 3px; - border-bottom-right-radius: 0; - border-bottom-left-radius: 0; } - -.navbar-btn { - margin-top: 34.5px; - margin-bottom: 34.5px; } - .navbar-btn.btn-sm, .btn-group-sm > .navbar-btn.btn { - margin-top: 39.5px; - margin-bottom: 39.5px; } - .navbar-btn.btn-xs, .btn-group-xs > .navbar-btn.btn { - margin-top: 44px; - margin-bottom: 44px; } - -.navbar-text { - margin-top: 41.5px; - margin-bottom: 41.5px; } - @media (min-width: 768px) { - .navbar-text { - float: left; - margin-left: 15px; - margin-right: 15px; } } - -@media (min-width: 768px) { - .navbar-left { - float: left !important; } - - .navbar-right { - float: right !important; - margin-right: -15px; } - .navbar-right ~ .navbar-right { - margin-right: 0; } } -.navbar-default { - background-color: #fff; - border-color: transparent; } - .navbar-default .navbar-brand { - color: #444; } - .navbar-default .navbar-brand:hover, .navbar-default .navbar-brand:focus { - color: #222; - background-color: transparent; } - .navbar-default .navbar-text { - color: #bbb; } - .navbar-default .navbar-nav > li > a { - color: #444; } - .navbar-default .navbar-nav > li > a:hover, .navbar-default .navbar-nav > li > a:focus { - color: #222; - background-color: transparent; } - .navbar-default .navbar-nav > .active > a, .navbar-default .navbar-nav > .active > a:hover, .navbar-default .navbar-nav > .active > a:focus { - color: #212121; - background-color: #fcfcfc; } - .navbar-default .navbar-nav > .disabled > a, .navbar-default .navbar-nav > .disabled > a:hover, .navbar-default .navbar-nav > .disabled > a:focus { - color: #ccc; - background-color: transparent; } - .navbar-default .navbar-toggle { - border-color: transparent; } - .navbar-default .navbar-toggle:hover, .navbar-default .navbar-toggle:focus { - background-color: transparent; } - .navbar-default .navbar-toggle .icon-bar { - background-color: rgba(0, 0, 0, 0.5); } - .navbar-default .navbar-collapse, - .navbar-default .navbar-form { - border-color: transparent; } - .navbar-default .navbar-nav > .open > a, .navbar-default .navbar-nav > .open > a:hover, .navbar-default .navbar-nav > .open > a:focus { - background-color: #fcfcfc; - color: #212121; } - @media (max-width: 767px) { - .navbar-default .navbar-nav .open .dropdown-menu > li > a { - color: #444; } - .navbar-default .navbar-nav .open .dropdown-menu > li > a:hover, .navbar-default .navbar-nav .open .dropdown-menu > li > a:focus { - color: #222; - background-color: transparent; } - .navbar-default .navbar-nav .open .dropdown-menu > .active > a, .navbar-default .navbar-nav .open .dropdown-menu > .active > a:hover, .navbar-default .navbar-nav .open .dropdown-menu > .active > a:focus { - color: #212121; - background-color: #fcfcfc; } - .navbar-default .navbar-nav .open .dropdown-menu > .disabled > a, .navbar-default .navbar-nav .open .dropdown-menu > .disabled > a:hover, .navbar-default .navbar-nav .open .dropdown-menu > .disabled > a:focus { - color: #ccc; - background-color: transparent; } } - .navbar-default .navbar-link { - color: #444; } - .navbar-default .navbar-link:hover { - color: #222; } - .navbar-default .btn-link { - color: #444; } - .navbar-default .btn-link:hover, .navbar-default .btn-link:focus { - color: #222; } - .navbar-default .btn-link[disabled]:hover, .navbar-default .btn-link[disabled]:focus, fieldset[disabled] .navbar-default .btn-link:hover, fieldset[disabled] .navbar-default .btn-link:focus { - color: #ccc; } - -.navbar-inverse { - background-color: #5a9ddb; - border-color: transparent; } - .navbar-inverse .navbar-brand { - color: #d8e8f6; } - .navbar-inverse .navbar-brand:hover, .navbar-inverse .navbar-brand:focus { - color: #fff; - background-color: transparent; } - .navbar-inverse .navbar-text { - color: #bbb; } - .navbar-inverse .navbar-nav > li > a { - color: #d8e8f6; } - .navbar-inverse .navbar-nav > li > a:hover, .navbar-inverse .navbar-nav > li > a:focus { - color: #fff; - background-color: transparent; } - .navbar-inverse .navbar-nav > .active > a, .navbar-inverse .navbar-nav > .active > a:hover, .navbar-inverse .navbar-nav > .active > a:focus { - color: #fff; - background-color: #3084d2; } - .navbar-inverse .navbar-nav > .disabled > a, .navbar-inverse .navbar-nav > .disabled > a:hover, .navbar-inverse .navbar-nav > .disabled > a:focus { - color: #444; - background-color: transparent; } - .navbar-inverse .navbar-toggle { - border-color: transparent; } - .navbar-inverse .navbar-toggle:hover, .navbar-inverse .navbar-toggle:focus { - background-color: transparent; } - .navbar-inverse .navbar-toggle .icon-bar { - background-color: rgba(0, 0, 0, 0.5); } - .navbar-inverse .navbar-collapse, - .navbar-inverse .navbar-form { - border-color: #3d8cd5; } - .navbar-inverse .navbar-nav > .open > a, .navbar-inverse .navbar-nav > .open > a:hover, .navbar-inverse .navbar-nav > .open > a:focus { - background-color: #3084d2; - color: #fff; } - @media (max-width: 767px) { - .navbar-inverse .navbar-nav .open .dropdown-menu > .dropdown-header { - border-color: transparent; } - .navbar-inverse .navbar-nav .open .dropdown-menu .divider { - background-color: transparent; } - .navbar-inverse .navbar-nav .open .dropdown-menu > li > a { - color: #d8e8f6; } - .navbar-inverse .navbar-nav .open .dropdown-menu > li > a:hover, .navbar-inverse .navbar-nav .open .dropdown-menu > li > a:focus { - color: #fff; - background-color: transparent; } - .navbar-inverse .navbar-nav .open .dropdown-menu > .active > a, .navbar-inverse .navbar-nav .open .dropdown-menu > .active > a:hover, .navbar-inverse .navbar-nav .open .dropdown-menu > .active > a:focus { - color: #fff; - background-color: #3084d2; } - .navbar-inverse .navbar-nav .open .dropdown-menu > .disabled > a, .navbar-inverse .navbar-nav .open .dropdown-menu > .disabled > a:hover, .navbar-inverse .navbar-nav .open .dropdown-menu > .disabled > a:focus { - color: #444; - background-color: transparent; } } - .navbar-inverse .navbar-link { - color: #d8e8f6; } - .navbar-inverse .navbar-link:hover { - color: #fff; } - .navbar-inverse .btn-link { - color: #d8e8f6; } - .navbar-inverse .btn-link:hover, .navbar-inverse .btn-link:focus { - color: #fff; } - .navbar-inverse .btn-link[disabled]:hover, .navbar-inverse .btn-link[disabled]:focus, fieldset[disabled] .navbar-inverse .btn-link:hover, fieldset[disabled] .navbar-inverse .btn-link:focus { - color: #444; } - -.breadcrumb { - padding: 8px 15px; - margin-bottom: 27px; - list-style: none; - background-color: #f5f5f5; - border-radius: 3px; } - .breadcrumb > li { - display: inline-block; } - .breadcrumb > li + li:before { - content: "/ "; - padding: 0 5px; - color: #ccc; } - .breadcrumb > .active { - color: #bbb; } - -.pagination { - display: inline-block; - padding-left: 0; - margin: 27px 0; - border-radius: 3px; } - .pagination > li { - display: inline; } - .pagination > li > a, - .pagination > li > span { - position: relative; - float: left; - padding: 6px 16px; - line-height: 1.846; - text-decoration: none; - color: #5a9ddb; - background-color: #fff; - border: 1px solid #ddd; - margin-left: -1px; } - .pagination > li:first-child > a, - .pagination > li:first-child > span { - margin-left: 0; - border-bottom-left-radius: 3px; - border-top-left-radius: 3px; } - .pagination > li:last-child > a, - .pagination > li:last-child > span { - border-bottom-right-radius: 3px; - border-top-right-radius: 3px; } - .pagination > li > a:hover, .pagination > li > a:focus, - .pagination > li > span:hover, - .pagination > li > span:focus { - z-index: 2; - color: #2a77bf; - background-color: #eeeeee; - border-color: #ddd; } - .pagination > .active > a, .pagination > .active > a:hover, .pagination > .active > a:focus, - .pagination > .active > span, - .pagination > .active > span:hover, - .pagination > .active > span:focus { - z-index: 3; - color: #fff; - background-color: #5a9ddb; - border-color: #5a9ddb; - cursor: default; } - .pagination > .disabled > span, - .pagination > .disabled > span:hover, - .pagination > .disabled > span:focus, - .pagination > .disabled > a, - .pagination > .disabled > a:hover, - .pagination > .disabled > a:focus { - color: #bbb; - background-color: #fff; - border-color: #ddd; - cursor: not-allowed; } - -.pagination-lg > li > a, -.pagination-lg > li > span { - padding: 10px 16px; - font-size: 19px; - line-height: 1.33333; } -.pagination-lg > li:first-child > a, -.pagination-lg > li:first-child > span { - border-bottom-left-radius: 3px; - border-top-left-radius: 3px; } -.pagination-lg > li:last-child > a, -.pagination-lg > li:last-child > span { - border-bottom-right-radius: 3px; - border-top-right-radius: 3px; } - -.pagination-sm > li > a, -.pagination-sm > li > span { - padding: 5px 10px; - font-size: 13px; - line-height: 1.5; } -.pagination-sm > li:first-child > a, -.pagination-sm > li:first-child > span { - border-bottom-left-radius: 3px; - border-top-left-radius: 3px; } -.pagination-sm > li:last-child > a, -.pagination-sm > li:last-child > span { - border-bottom-right-radius: 3px; - border-top-right-radius: 3px; } - -.pager { - padding-left: 0; - margin: 27px 0; - list-style: none; - text-align: center; } - .pager:before, .pager:after { - content: " "; - display: table; } - .pager:after { - clear: both; } - .pager li { - display: inline; } - .pager li > a, - .pager li > span { - display: inline-block; - padding: 5px 14px; - background-color: #fff; - border: 1px solid #ddd; - border-radius: 15px; } - .pager li > a:hover, - .pager li > a:focus { - text-decoration: none; - background-color: #eeeeee; } - .pager .next > a, - .pager .next > span { - float: right; } - .pager .previous > a, - .pager .previous > span { - float: left; } - .pager .disabled > a, - .pager .disabled > a:hover, - .pager .disabled > a:focus, - .pager .disabled > span { - color: #bbb; - background-color: #fff; - cursor: not-allowed; } - -.label { - display: inline; - padding: .2em .6em .3em; - font-size: 75%; - font-weight: bold; - line-height: 1; - color: #fff; - text-align: center; - white-space: nowrap; - vertical-align: baseline; - border-radius: .25em; } - .label:empty { - display: none; } - .btn .label { - position: relative; - top: -1px; } - -a.label:hover, a.label:focus { - color: #fff; - text-decoration: none; - cursor: pointer; } - -.label-default { - background-color: #bbb; } - .label-default[href]:hover, .label-default[href]:focus { - background-color: #a2a2a2; } - -.label-primary { - background-color: #5a9ddb; } - .label-primary[href]:hover, .label-primary[href]:focus { - background-color: #3084d2; } - -.label-success { - background-color: #4CAF50; } - .label-success[href]:hover, .label-success[href]:focus { - background-color: #3d8b40; } - -.label-info { - background-color: #9C27B0; } - .label-info[href]:hover, .label-info[href]:focus { - background-color: #771e86; } - -.label-warning { - background-color: #ff9800; } - .label-warning[href]:hover, .label-warning[href]:focus { - background-color: #cc7a00; } - -.label-danger { - background-color: #e51c23; } - .label-danger[href]:hover, .label-danger[href]:focus { - background-color: #b9151b; } - -.badge { - display: inline-block; - min-width: 10px; - padding: 3px 7px; - font-size: 13px; - font-weight: normal; - color: #fff; - line-height: 1; - vertical-align: middle; - white-space: nowrap; - text-align: center; - background-color: #bbb; - border-radius: 10px; } - .badge:empty { - display: none; } - .btn .badge { - position: relative; - top: -1px; } - .btn-xs .badge, .btn-group-xs > .btn .badge, .btn-group-xs > .btn .badge { - top: 0; - padding: 1px 5px; } - .list-group-item.active > .badge, .nav-pills > .active > a > .badge { - color: #5a9ddb; - background-color: #fff; } - .list-group-item > .badge { - float: right; } - .list-group-item > .badge + .badge { - margin-right: 5px; } - .nav-pills > li > a > .badge { - margin-left: 3px; } - -a.badge:hover, a.badge:focus { - color: #fff; - text-decoration: none; - cursor: pointer; } - -.jumbotron { - padding-top: 30px; - padding-bottom: 30px; - margin-bottom: 30px; - color: inherit; - background-color: #f5f5f5; } - .jumbotron h1, - .jumbotron .h1 { - color: #444; } - .jumbotron p { - margin-bottom: 15px; - font-size: 23px; - font-weight: 200; } - .jumbotron > hr { - border-top-color: gainsboro; } - .container .jumbotron, .container-fluid .jumbotron { - border-radius: 3px; - padding-left: 15px; - padding-right: 15px; } - .jumbotron .container { - max-width: 100%; } - @media screen and (min-width: 768px) { - .jumbotron { - padding-top: 48px; - padding-bottom: 48px; } - .container .jumbotron, .container-fluid .jumbotron { - padding-left: 60px; - padding-right: 60px; } - .jumbotron h1, - .jumbotron .h1 { - font-size: 68px; } } - -.thumbnail { - display: block; - padding: 4px; - margin-bottom: 27px; - line-height: 1.846; - background-color: #fff; - border: 1px solid #ddd; - border-radius: 3px; - -webkit-transition: border 0.2s ease-in-out; - -o-transition: border 0.2s ease-in-out; - transition: border 0.2s ease-in-out; } - .thumbnail > img, - .thumbnail a > img { - display: block; - max-width: 100%; - height: auto; - margin-left: auto; - margin-right: auto; } - .thumbnail .caption { - padding: 9px; - color: #444; } - -a.thumbnail:hover, -a.thumbnail:focus, -a.thumbnail.active { - border-color: #5a9ddb; } - -.alert { - padding: 15px; - margin-bottom: 27px; - border: 1px solid transparent; - border-radius: 3px; } - .alert h4 { - margin-top: 0; - color: inherit; } - .alert .alert-link { - font-weight: bold; } - .alert > p, - .alert > ul { - margin-bottom: 0; } - .alert > p + p { - margin-top: 5px; } - -.alert-dismissable, -.alert-dismissible { - padding-right: 35px; } - .alert-dismissable .close, - .alert-dismissible .close { - position: relative; - top: -2px; - right: -21px; - color: inherit; } - -.alert-success { - background-color: #dff0d8; - border-color: #d6e9c6; - color: #4CAF50; } - .alert-success hr { - border-top-color: #c9e2b3; } - .alert-success .alert-link { - color: #3d8b40; } - -.alert-info { - background-color: #e1bee7; - border-color: #cba4dd; - color: #9C27B0; } - .alert-info hr { - border-top-color: #c191d6; } - .alert-info .alert-link { - color: #771e86; } - -.alert-warning { - background-color: #ffe0b2; - border-color: #ffc599; - color: #ff9800; } - .alert-warning hr { - border-top-color: #ffb67f; } - .alert-warning .alert-link { - color: #cc7a00; } - -.alert-danger { - background-color: #f9bdbb; - border-color: #f7a4af; - color: #e51c23; } - .alert-danger hr { - border-top-color: #f58c9a; } - .alert-danger .alert-link { - color: #b9151b; } - -@-webkit-keyframes progress-bar-stripes { - from { - background-position: 40px 0; } - to { - background-position: 0 0; } } -@keyframes progress-bar-stripes { - from { - background-position: 40px 0; } - to { - background-position: 0 0; } } -.progress { - overflow: hidden; - height: 27px; - margin-bottom: 27px; - background-color: #f5f5f5; - border-radius: 3px; - -webkit-box-shadow: inset 0 1px 2px rgba(0, 0, 0, 0.1); - box-shadow: inset 0 1px 2px rgba(0, 0, 0, 0.1); } - -.progress-bar { - float: left; - width: 0%; - height: 100%; - font-size: 13px; - line-height: 27px; - color: #fff; - text-align: center; - background-color: #5a9ddb; - -webkit-box-shadow: inset 0 -1px 0 rgba(0, 0, 0, 0.15); - box-shadow: inset 0 -1px 0 rgba(0, 0, 0, 0.15); - -webkit-transition: width 0.6s ease; - -o-transition: width 0.6s ease; - transition: width 0.6s ease; } - -.progress-striped .progress-bar, -.progress-bar-striped { - background-image: -webkit-linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent); - background-image: -o-linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent); - background-image: linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent); - background-size: 40px 40px; } - -.progress.active .progress-bar, -.progress-bar.active { - -webkit-animation: progress-bar-stripes 2s linear infinite; - -o-animation: progress-bar-stripes 2s linear infinite; - animation: progress-bar-stripes 2s linear infinite; } - -.progress-bar-success { - background-color: #4CAF50; } - .progress-striped .progress-bar-success { - background-image: -webkit-linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent); - background-image: -o-linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent); - background-image: linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent); } - -.progress-bar-info { - background-color: #9C27B0; } - .progress-striped .progress-bar-info { - background-image: -webkit-linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent); - background-image: -o-linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent); - background-image: linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent); } - -.progress-bar-warning { - background-color: #ff9800; } - .progress-striped .progress-bar-warning { - background-image: -webkit-linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent); - background-image: -o-linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent); - background-image: linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent); } - -.progress-bar-danger { - background-color: #e51c23; } - .progress-striped .progress-bar-danger { - background-image: -webkit-linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent); - background-image: -o-linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent); - background-image: linear-gradient(45deg, rgba(255, 255, 255, 0.15) 25%, transparent 25%, transparent 50%, rgba(255, 255, 255, 0.15) 50%, rgba(255, 255, 255, 0.15) 75%, transparent 75%, transparent); } - -.media { - margin-top: 15px; } - .media:first-child { - margin-top: 0; } - -.media, -.media-body { - zoom: 1; - overflow: hidden; } - -.media-body { - width: 10000px; } - -.media-object { - display: block; } - .media-object.img-thumbnail { - max-width: none; } - -.media-right, -.media > .pull-right { - padding-left: 10px; } - -.media-left, -.media > .pull-left { - padding-right: 10px; } - -.media-left, -.media-right, -.media-body { - display: table-cell; - vertical-align: top; } - -.media-middle { - vertical-align: middle; } - -.media-bottom { - vertical-align: bottom; } - -.media-heading { - margin-top: 0; - margin-bottom: 5px; } - -.media-list { - padding-left: 0; - list-style: none; } - -.list-group { - margin-bottom: 20px; - padding-left: 0; } - -.list-group-item { - position: relative; - display: block; - padding: 10px 15px; - margin-bottom: -1px; - background-color: #fff; - border: 1px solid #ddd; } - .list-group-item:first-child { - border-top-right-radius: 3px; - border-top-left-radius: 3px; } - .list-group-item:last-child { - margin-bottom: 0; - border-bottom-right-radius: 3px; - border-bottom-left-radius: 3px; } - -a.list-group-item, -button.list-group-item { - color: #555; } - a.list-group-item .list-group-item-heading, - button.list-group-item .list-group-item-heading { - color: #333; } - a.list-group-item:hover, a.list-group-item:focus, - button.list-group-item:hover, - button.list-group-item:focus { - text-decoration: none; - color: #555; - background-color: #f5f5f5; } - -button.list-group-item { - width: 100%; - text-align: left; } - -.list-group-item.disabled, .list-group-item.disabled:hover, .list-group-item.disabled:focus { - background-color: #eeeeee; - color: #bbb; - cursor: not-allowed; } - .list-group-item.disabled .list-group-item-heading, .list-group-item.disabled:hover .list-group-item-heading, .list-group-item.disabled:focus .list-group-item-heading { - color: inherit; } - .list-group-item.disabled .list-group-item-text, .list-group-item.disabled:hover .list-group-item-text, .list-group-item.disabled:focus .list-group-item-text { - color: #bbb; } -.list-group-item.active, .list-group-item.active:hover, .list-group-item.active:focus { - z-index: 2; - color: #fff; - background-color: #5a9ddb; - border-color: #5a9ddb; } - .list-group-item.active .list-group-item-heading, - .list-group-item.active .list-group-item-heading > small, - .list-group-item.active .list-group-item-heading > .small, .list-group-item.active:hover .list-group-item-heading, - .list-group-item.active:hover .list-group-item-heading > small, - .list-group-item.active:hover .list-group-item-heading > .small, .list-group-item.active:focus .list-group-item-heading, - .list-group-item.active:focus .list-group-item-heading > small, - .list-group-item.active:focus .list-group-item-heading > .small { - color: inherit; } - .list-group-item.active .list-group-item-text, .list-group-item.active:hover .list-group-item-text, .list-group-item.active:focus .list-group-item-text { - color: white; } - -.list-group-item-success { - color: #4CAF50; - background-color: #dff0d8; } - -a.list-group-item-success, -button.list-group-item-success { - color: #4CAF50; } - a.list-group-item-success .list-group-item-heading, - button.list-group-item-success .list-group-item-heading { - color: inherit; } - a.list-group-item-success:hover, a.list-group-item-success:focus, - button.list-group-item-success:hover, - button.list-group-item-success:focus { - color: #4CAF50; - background-color: #d0e9c6; } - a.list-group-item-success.active, a.list-group-item-success.active:hover, a.list-group-item-success.active:focus, - button.list-group-item-success.active, - button.list-group-item-success.active:hover, - button.list-group-item-success.active:focus { - color: #fff; - background-color: #4CAF50; - border-color: #4CAF50; } - -.list-group-item-info { - color: #9C27B0; - background-color: #e1bee7; } - -a.list-group-item-info, -button.list-group-item-info { - color: #9C27B0; } - a.list-group-item-info .list-group-item-heading, - button.list-group-item-info .list-group-item-heading { - color: inherit; } - a.list-group-item-info:hover, a.list-group-item-info:focus, - button.list-group-item-info:hover, - button.list-group-item-info:focus { - color: #9C27B0; - background-color: #d8abe0; } - a.list-group-item-info.active, a.list-group-item-info.active:hover, a.list-group-item-info.active:focus, - button.list-group-item-info.active, - button.list-group-item-info.active:hover, - button.list-group-item-info.active:focus { - color: #fff; - background-color: #9C27B0; - border-color: #9C27B0; } - -.list-group-item-warning { - color: #ff9800; - background-color: #ffe0b2; } - -a.list-group-item-warning, -button.list-group-item-warning { - color: #ff9800; } - a.list-group-item-warning .list-group-item-heading, - button.list-group-item-warning .list-group-item-heading { - color: inherit; } - a.list-group-item-warning:hover, a.list-group-item-warning:focus, - button.list-group-item-warning:hover, - button.list-group-item-warning:focus { - color: #ff9800; - background-color: #ffd699; } - a.list-group-item-warning.active, a.list-group-item-warning.active:hover, a.list-group-item-warning.active:focus, - button.list-group-item-warning.active, - button.list-group-item-warning.active:hover, - button.list-group-item-warning.active:focus { - color: #fff; - background-color: #ff9800; - border-color: #ff9800; } - -.list-group-item-danger { - color: #e51c23; - background-color: #f9bdbb; } - -a.list-group-item-danger, -button.list-group-item-danger { - color: #e51c23; } - a.list-group-item-danger .list-group-item-heading, - button.list-group-item-danger .list-group-item-heading { - color: inherit; } - a.list-group-item-danger:hover, a.list-group-item-danger:focus, - button.list-group-item-danger:hover, - button.list-group-item-danger:focus { - color: #e51c23; - background-color: #f7a6a4; } - a.list-group-item-danger.active, a.list-group-item-danger.active:hover, a.list-group-item-danger.active:focus, - button.list-group-item-danger.active, - button.list-group-item-danger.active:hover, - button.list-group-item-danger.active:focus { - color: #fff; - background-color: #e51c23; - border-color: #e51c23; } - -.list-group-item-heading { - margin-top: 0; - margin-bottom: 5px; } - -.list-group-item-text { - margin-bottom: 0; - line-height: 1.3; } - -.panel { - margin-bottom: 27px; - background-color: #fff; - border: 1px solid transparent; - border-radius: 3px; - -webkit-box-shadow: 0 1px 1px rgba(0, 0, 0, 0.05); - box-shadow: 0 1px 1px rgba(0, 0, 0, 0.05); } - -.panel-body { - padding: 15px; } - .panel-body:before, .panel-body:after { - content: " "; - display: table; } - .panel-body:after { - clear: both; } - -.panel-heading { - padding: 10px 15px; - border-bottom: 1px solid transparent; - border-top-right-radius: 2px; - border-top-left-radius: 2px; } - .panel-heading > .dropdown .dropdown-toggle { - color: inherit; } - -.panel-title { - margin-top: 0; - margin-bottom: 0; - font-size: 17px; - color: inherit; } - .panel-title > a, - .panel-title > small, - .panel-title > .small, - .panel-title > small > a, - .panel-title > .small > a { - color: inherit; } - -.panel-footer { - padding: 10px 15px; - background-color: #f5f5f5; - border-top: 1px solid #ddd; - border-bottom-right-radius: 2px; - border-bottom-left-radius: 2px; } - -.panel > .list-group, -.panel > .panel-collapse > .list-group { - margin-bottom: 0; } - .panel > .list-group .list-group-item, - .panel > .panel-collapse > .list-group .list-group-item { - border-width: 1px 0; - border-radius: 0; } - .panel > .list-group:first-child .list-group-item:first-child, - .panel > .panel-collapse > .list-group:first-child .list-group-item:first-child { - border-top: 0; - border-top-right-radius: 2px; - border-top-left-radius: 2px; } - .panel > .list-group:last-child .list-group-item:last-child, - .panel > .panel-collapse > .list-group:last-child .list-group-item:last-child { - border-bottom: 0; - border-bottom-right-radius: 2px; - border-bottom-left-radius: 2px; } -.panel > .panel-heading + .panel-collapse > .list-group .list-group-item:first-child { - border-top-right-radius: 0; - border-top-left-radius: 0; } - -.panel-heading + .list-group .list-group-item:first-child { - border-top-width: 0; } - -.list-group + .panel-footer { - border-top-width: 0; } - -.panel > .table, -.panel > .table-responsive > .table, -.panel > .panel-collapse > .table { - margin-bottom: 0; } - .panel > .table caption, - .panel > .table-responsive > .table caption, - .panel > .panel-collapse > .table caption { - padding-left: 15px; - padding-right: 15px; } -.panel > .table:first-child, -.panel > .table-responsive:first-child > .table:first-child { - border-top-right-radius: 2px; - border-top-left-radius: 2px; } - .panel > .table:first-child > thead:first-child > tr:first-child, - .panel > .table:first-child > tbody:first-child > tr:first-child, - .panel > .table-responsive:first-child > .table:first-child > thead:first-child > tr:first-child, - .panel > .table-responsive:first-child > .table:first-child > tbody:first-child > tr:first-child { - border-top-left-radius: 2px; - border-top-right-radius: 2px; } - .panel > .table:first-child > thead:first-child > tr:first-child td:first-child, - .panel > .table:first-child > thead:first-child > tr:first-child th:first-child, - .panel > .table:first-child > tbody:first-child > tr:first-child td:first-child, - .panel > .table:first-child > tbody:first-child > tr:first-child th:first-child, - .panel > .table-responsive:first-child > .table:first-child > thead:first-child > tr:first-child td:first-child, - .panel > .table-responsive:first-child > .table:first-child > thead:first-child > tr:first-child th:first-child, - .panel > .table-responsive:first-child > .table:first-child > tbody:first-child > tr:first-child td:first-child, - .panel > .table-responsive:first-child > .table:first-child > tbody:first-child > tr:first-child th:first-child { - border-top-left-radius: 2px; } - .panel > .table:first-child > thead:first-child > tr:first-child td:last-child, - .panel > .table:first-child > thead:first-child > tr:first-child th:last-child, - .panel > .table:first-child > tbody:first-child > tr:first-child td:last-child, - .panel > .table:first-child > tbody:first-child > tr:first-child th:last-child, - .panel > .table-responsive:first-child > .table:first-child > thead:first-child > tr:first-child td:last-child, - .panel > .table-responsive:first-child > .table:first-child > thead:first-child > tr:first-child th:last-child, - .panel > .table-responsive:first-child > .table:first-child > tbody:first-child > tr:first-child td:last-child, - .panel > .table-responsive:first-child > .table:first-child > tbody:first-child > tr:first-child th:last-child { - border-top-right-radius: 2px; } -.panel > .table:last-child, -.panel > .table-responsive:last-child > .table:last-child { - border-bottom-right-radius: 2px; - border-bottom-left-radius: 2px; } - .panel > .table:last-child > tbody:last-child > tr:last-child, - .panel > .table:last-child > tfoot:last-child > tr:last-child, - .panel > .table-responsive:last-child > .table:last-child > tbody:last-child > tr:last-child, - .panel > .table-responsive:last-child > .table:last-child > tfoot:last-child > tr:last-child { - border-bottom-left-radius: 2px; - border-bottom-right-radius: 2px; } - .panel > .table:last-child > tbody:last-child > tr:last-child td:first-child, - .panel > .table:last-child > tbody:last-child > tr:last-child th:first-child, - .panel > .table:last-child > tfoot:last-child > tr:last-child td:first-child, - .panel > .table:last-child > tfoot:last-child > tr:last-child th:first-child, - .panel > .table-responsive:last-child > .table:last-child > tbody:last-child > tr:last-child td:first-child, - .panel > .table-responsive:last-child > .table:last-child > tbody:last-child > tr:last-child th:first-child, - .panel > .table-responsive:last-child > .table:last-child > tfoot:last-child > tr:last-child td:first-child, - .panel > .table-responsive:last-child > .table:last-child > tfoot:last-child > tr:last-child th:first-child { - border-bottom-left-radius: 2px; } - .panel > .table:last-child > tbody:last-child > tr:last-child td:last-child, - .panel > .table:last-child > tbody:last-child > tr:last-child th:last-child, - .panel > .table:last-child > tfoot:last-child > tr:last-child td:last-child, - .panel > .table:last-child > tfoot:last-child > tr:last-child th:last-child, - .panel > .table-responsive:last-child > .table:last-child > tbody:last-child > tr:last-child td:last-child, - .panel > .table-responsive:last-child > .table:last-child > tbody:last-child > tr:last-child th:last-child, - .panel > .table-responsive:last-child > .table:last-child > tfoot:last-child > tr:last-child td:last-child, - .panel > .table-responsive:last-child > .table:last-child > tfoot:last-child > tr:last-child th:last-child { - border-bottom-right-radius: 2px; } -.panel > .panel-body + .table, -.panel > .panel-body + .table-responsive, -.panel > .table + .panel-body, -.panel > .table-responsive + .panel-body { - border-top: 1px solid #ddd; } -.panel > .table > tbody:first-child > tr:first-child th, -.panel > .table > tbody:first-child > tr:first-child td { - border-top: 0; } -.panel > .table-bordered, -.panel > .table-responsive > .table-bordered { - border: 0; } - .panel > .table-bordered > thead > tr > th:first-child, - .panel > .table-bordered > thead > tr > td:first-child, - .panel > .table-bordered > tbody > tr > th:first-child, - .panel > .table-bordered > tbody > tr > td:first-child, - .panel > .table-bordered > tfoot > tr > th:first-child, - .panel > .table-bordered > tfoot > tr > td:first-child, - .panel > .table-responsive > .table-bordered > thead > tr > th:first-child, - .panel > .table-responsive > .table-bordered > thead > tr > td:first-child, - .panel > .table-responsive > .table-bordered > tbody > tr > th:first-child, - .panel > .table-responsive > .table-bordered > tbody > tr > td:first-child, - .panel > .table-responsive > .table-bordered > tfoot > tr > th:first-child, - .panel > .table-responsive > .table-bordered > tfoot > tr > td:first-child { - border-left: 0; } - .panel > .table-bordered > thead > tr > th:last-child, - .panel > .table-bordered > thead > tr > td:last-child, - .panel > .table-bordered > tbody > tr > th:last-child, - .panel > .table-bordered > tbody > tr > td:last-child, - .panel > .table-bordered > tfoot > tr > th:last-child, - .panel > .table-bordered > tfoot > tr > td:last-child, - .panel > .table-responsive > .table-bordered > thead > tr > th:last-child, - .panel > .table-responsive > .table-bordered > thead > tr > td:last-child, - .panel > .table-responsive > .table-bordered > tbody > tr > th:last-child, - .panel > .table-responsive > .table-bordered > tbody > tr > td:last-child, - .panel > .table-responsive > .table-bordered > tfoot > tr > th:last-child, - .panel > .table-responsive > .table-bordered > tfoot > tr > td:last-child { - border-right: 0; } - .panel > .table-bordered > thead > tr:first-child > td, - .panel > .table-bordered > thead > tr:first-child > th, - .panel > .table-bordered > tbody > tr:first-child > td, - .panel > .table-bordered > tbody > tr:first-child > th, - .panel > .table-responsive > .table-bordered > thead > tr:first-child > td, - .panel > .table-responsive > .table-bordered > thead > tr:first-child > th, - .panel > .table-responsive > .table-bordered > tbody > tr:first-child > td, - .panel > .table-responsive > .table-bordered > tbody > tr:first-child > th { - border-bottom: 0; } - .panel > .table-bordered > tbody > tr:last-child > td, - .panel > .table-bordered > tbody > tr:last-child > th, - .panel > .table-bordered > tfoot > tr:last-child > td, - .panel > .table-bordered > tfoot > tr:last-child > th, - .panel > .table-responsive > .table-bordered > tbody > tr:last-child > td, - .panel > .table-responsive > .table-bordered > tbody > tr:last-child > th, - .panel > .table-responsive > .table-bordered > tfoot > tr:last-child > td, - .panel > .table-responsive > .table-bordered > tfoot > tr:last-child > th { - border-bottom: 0; } -.panel > .table-responsive { - border: 0; - margin-bottom: 0; } - -.panel-group { - margin-bottom: 27px; } - .panel-group .panel { - margin-bottom: 0; - border-radius: 3px; } - .panel-group .panel + .panel { - margin-top: 5px; } - .panel-group .panel-heading { - border-bottom: 0; } - .panel-group .panel-heading + .panel-collapse > .panel-body, - .panel-group .panel-heading + .panel-collapse > .list-group { - border-top: 1px solid #ddd; } - .panel-group .panel-footer { - border-top: 0; } - .panel-group .panel-footer + .panel-collapse .panel-body { - border-bottom: 1px solid #ddd; } - -.panel-default { - border-color: #ddd; } - .panel-default > .panel-heading { - color: #212121; - background-color: #f5f5f5; - border-color: #ddd; } - .panel-default > .panel-heading + .panel-collapse > .panel-body { - border-top-color: #ddd; } - .panel-default > .panel-heading .badge { - color: #f5f5f5; - background-color: #212121; } - .panel-default > .panel-footer + .panel-collapse > .panel-body { - border-bottom-color: #ddd; } - -.panel-primary { - border-color: #5a9ddb; } - .panel-primary > .panel-heading { - color: #fff; - background-color: #5a9ddb; - border-color: #5a9ddb; } - .panel-primary > .panel-heading + .panel-collapse > .panel-body { - border-top-color: #5a9ddb; } - .panel-primary > .panel-heading .badge { - color: #5a9ddb; - background-color: #fff; } - .panel-primary > .panel-footer + .panel-collapse > .panel-body { - border-bottom-color: #5a9ddb; } - -.panel-success { - border-color: #d6e9c6; } - .panel-success > .panel-heading { - color: #fff; - background-color: #4CAF50; - border-color: #d6e9c6; } - .panel-success > .panel-heading + .panel-collapse > .panel-body { - border-top-color: #d6e9c6; } - .panel-success > .panel-heading .badge { - color: #4CAF50; - background-color: #fff; } - .panel-success > .panel-footer + .panel-collapse > .panel-body { - border-bottom-color: #d6e9c6; } - -.panel-info { - border-color: #cba4dd; } - .panel-info > .panel-heading { - color: #fff; - background-color: #9C27B0; - border-color: #cba4dd; } - .panel-info > .panel-heading + .panel-collapse > .panel-body { - border-top-color: #cba4dd; } - .panel-info > .panel-heading .badge { - color: #9C27B0; - background-color: #fff; } - .panel-info > .panel-footer + .panel-collapse > .panel-body { - border-bottom-color: #cba4dd; } - -.panel-warning { - border-color: #ffc599; } - .panel-warning > .panel-heading { - color: #fff; - background-color: #ff9800; - border-color: #ffc599; } - .panel-warning > .panel-heading + .panel-collapse > .panel-body { - border-top-color: #ffc599; } - .panel-warning > .panel-heading .badge { - color: #ff9800; - background-color: #fff; } - .panel-warning > .panel-footer + .panel-collapse > .panel-body { - border-bottom-color: #ffc599; } - -.panel-danger { - border-color: #f7a4af; } - .panel-danger > .panel-heading { - color: #fff; - background-color: #e51c23; - border-color: #f7a4af; } - .panel-danger > .panel-heading + .panel-collapse > .panel-body { - border-top-color: #f7a4af; } - .panel-danger > .panel-heading .badge { - color: #e51c23; - background-color: #fff; } - .panel-danger > .panel-footer + .panel-collapse > .panel-body { - border-bottom-color: #f7a4af; } - -.embed-responsive { - position: relative; - display: block; - height: 0; - padding: 0; - overflow: hidden; } - .embed-responsive .embed-responsive-item, - .embed-responsive iframe, - .embed-responsive embed, - .embed-responsive object, - .embed-responsive video { - position: absolute; - top: 0; - left: 0; - bottom: 0; - height: 100%; - width: 100%; - border: 0; } - -.embed-responsive-16by9 { - padding-bottom: 56.25%; } - -.embed-responsive-4by3 { - padding-bottom: 75%; } - -.well { - min-height: 20px; - padding: 19px; - margin-bottom: 20px; - background-color: #f5f5f5; - border: 1px solid transparent; - border-radius: 3px; - -webkit-box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.05); - box-shadow: inset 0 1px 1px rgba(0, 0, 0, 0.05); } - .well blockquote { - border-color: #ddd; - border-color: rgba(0, 0, 0, 0.15); } - -.well-lg { - padding: 24px; - border-radius: 3px; } - -.well-sm { - padding: 9px; - border-radius: 3px; } - -.close { - float: right; - font-size: 22.5px; - font-weight: normal; - line-height: 1; - color: #000; - text-shadow: none; - opacity: 0.2; - filter: alpha(opacity=20); } - .close:hover, .close:focus { - color: #000; - text-decoration: none; - cursor: pointer; - opacity: 0.5; - filter: alpha(opacity=50); } - -button.close { - padding: 0; - cursor: pointer; - background: transparent; - border: 0; - -webkit-appearance: none; } - -.modal-open { - overflow: hidden; } - -.modal { - display: none; - overflow: hidden; - position: fixed; - top: 0; - right: 0; - bottom: 0; - left: 0; - z-index: 1050; - -webkit-overflow-scrolling: touch; - outline: 0; } - .modal.fade .modal-dialog { - -webkit-transform: translate(0, -25%); - -ms-transform: translate(0, -25%); - -o-transform: translate(0, -25%); - transform: translate(0, -25%); - -webkit-transition: -webkit-transform 0.3s ease-out; - -moz-transition: -moz-transform 0.3s ease-out; - -o-transition: -o-transform 0.3s ease-out; - transition: transform 0.3s ease-out; } - .modal.in .modal-dialog { - -webkit-transform: translate(0, 0); - -ms-transform: translate(0, 0); - -o-transform: translate(0, 0); - transform: translate(0, 0); } - -.modal-open .modal { - overflow-x: hidden; - overflow-y: auto; } - -.modal-dialog { - position: relative; - width: auto; - margin: 10px; } - -.modal-content { - position: relative; - background-color: #fff; - border: 1px solid #999; - border: 1px solid transparent; - border-radius: 3px; - -webkit-box-shadow: 0 3px 9px rgba(0, 0, 0, 0.5); - box-shadow: 0 3px 9px rgba(0, 0, 0, 0.5); - background-clip: padding-box; - outline: 0; } - -.modal-backdrop { - position: fixed; - top: 0; - right: 0; - bottom: 0; - left: 0; - z-index: 1040; - background-color: #000; } - .modal-backdrop.fade { - opacity: 0; - filter: alpha(opacity=0); } - .modal-backdrop.in { - opacity: 0.5; - filter: alpha(opacity=50); } - -.modal-header { - padding: 15px; - border-bottom: 1px solid transparent; } - .modal-header:before, .modal-header:after { - content: " "; - display: table; } - .modal-header:after { - clear: both; } - -.modal-header .close { - margin-top: -2px; } - -.modal-title { - margin: 0; - line-height: 1.846; } - -.modal-body { - position: relative; - padding: 15px; } - -.modal-footer { - padding: 15px; - text-align: right; - border-top: 1px solid transparent; } - .modal-footer:before, .modal-footer:after { - content: " "; - display: table; } - .modal-footer:after { - clear: both; } - .modal-footer .btn + .btn { - margin-left: 5px; - margin-bottom: 0; } - .modal-footer .btn-group .btn + .btn { - margin-left: -1px; } - .modal-footer .btn-block + .btn-block { - margin-left: 0; } - -.modal-scrollbar-measure { - position: absolute; - top: -9999px; - width: 50px; - height: 50px; - overflow: scroll; } - -@media (min-width: 768px) { - .modal-dialog { - width: 600px; - margin: 30px auto; } - - .modal-content { - -webkit-box-shadow: 0 5px 15px rgba(0, 0, 0, 0.5); - box-shadow: 0 5px 15px rgba(0, 0, 0, 0.5); } - - .modal-sm { - width: 300px; } } -@media (min-width: 992px) { - .modal-lg { - width: 900px; } } -.tooltip { - position: absolute; - z-index: 1070; - display: block; - font-family: "Source Sans Pro", "Helvetica Neue", Helvetica, Arial, sans-serif; - font-style: normal; - font-weight: normal; - letter-spacing: normal; - line-break: auto; - line-height: 1.846; - text-align: left; - text-align: start; - text-decoration: none; - text-shadow: none; - text-transform: none; - white-space: normal; - word-break: normal; - word-spacing: normal; - word-wrap: normal; - font-size: 13px; - opacity: 0; - filter: alpha(opacity=0); } - .tooltip.in { - opacity: 0.9; - filter: alpha(opacity=90); } - .tooltip.top { - margin-top: -3px; - padding: 5px 0; } - .tooltip.right { - margin-left: 3px; - padding: 0 5px; } - .tooltip.bottom { - margin-top: 3px; - padding: 5px 0; } - .tooltip.left { - margin-left: -3px; - padding: 0 5px; } - -.tooltip-inner { - max-width: 200px; - padding: 3px 8px; - color: #fff; - text-align: center; - background-color: #727272; - border-radius: 3px; } - -.tooltip-arrow { - position: absolute; - width: 0; - height: 0; - border-color: transparent; - border-style: solid; } - -.tooltip.top .tooltip-arrow { - bottom: 0; - left: 50%; - margin-left: -5px; - border-width: 5px 5px 0; - border-top-color: #727272; } -.tooltip.top-left .tooltip-arrow { - bottom: 0; - right: 5px; - margin-bottom: -5px; - border-width: 5px 5px 0; - border-top-color: #727272; } -.tooltip.top-right .tooltip-arrow { - bottom: 0; - left: 5px; - margin-bottom: -5px; - border-width: 5px 5px 0; - border-top-color: #727272; } -.tooltip.right .tooltip-arrow { - top: 50%; - left: 0; - margin-top: -5px; - border-width: 5px 5px 5px 0; - border-right-color: #727272; } -.tooltip.left .tooltip-arrow { - top: 50%; - right: 0; - margin-top: -5px; - border-width: 5px 0 5px 5px; - border-left-color: #727272; } -.tooltip.bottom .tooltip-arrow { - top: 0; - left: 50%; - margin-left: -5px; - border-width: 0 5px 5px; - border-bottom-color: #727272; } -.tooltip.bottom-left .tooltip-arrow { - top: 0; - right: 5px; - margin-top: -5px; - border-width: 0 5px 5px; - border-bottom-color: #727272; } -.tooltip.bottom-right .tooltip-arrow { - top: 0; - left: 5px; - margin-top: -5px; - border-width: 0 5px 5px; - border-bottom-color: #727272; } - -.popover { - position: absolute; - top: 0; - left: 0; - z-index: 1060; - display: none; - max-width: 276px; - padding: 1px; - font-family: "Source Sans Pro", "Helvetica Neue", Helvetica, Arial, sans-serif; - font-style: normal; - font-weight: normal; - letter-spacing: normal; - line-break: auto; - line-height: 1.846; - text-align: left; - text-align: start; - text-decoration: none; - text-shadow: none; - text-transform: none; - white-space: normal; - word-break: normal; - word-spacing: normal; - word-wrap: normal; - font-size: 15px; - background-color: #fff; - background-clip: padding-box; - border: 1px solid transparent; - border: 1px solid transparent; - border-radius: 3px; - -webkit-box-shadow: 0 5px 10px rgba(0, 0, 0, 0.2); - box-shadow: 0 5px 10px rgba(0, 0, 0, 0.2); } - .popover.top { - margin-top: -10px; } - .popover.right { - margin-left: 10px; } - .popover.bottom { - margin-top: 10px; } - .popover.left { - margin-left: -10px; } - -.popover-title { - margin: 0; - padding: 8px 14px; - font-size: 15px; - background-color: #f7f7f7; - border-bottom: 1px solid #ebebeb; - border-radius: 2px 2px 0 0; } - -.popover-content { - padding: 9px 14px; } - -.popover > .arrow, .popover > .arrow:after { - position: absolute; - display: block; - width: 0; - height: 0; - border-color: transparent; - border-style: solid; } - -.popover > .arrow { - border-width: 11px; } - -.popover > .arrow:after { - border-width: 10px; - content: ""; } - -.popover.top > .arrow { - left: 50%; - margin-left: -11px; - border-bottom-width: 0; - border-top-color: transparent; - border-top-color: fadein(transparent, 12%); - bottom: -11px; } - .popover.top > .arrow:after { - content: " "; - bottom: 1px; - margin-left: -10px; - border-bottom-width: 0; - border-top-color: #fff; } -.popover.right > .arrow { - top: 50%; - left: -11px; - margin-top: -11px; - border-left-width: 0; - border-right-color: transparent; - border-right-color: fadein(transparent, 12%); } - .popover.right > .arrow:after { - content: " "; - left: 1px; - bottom: -10px; - border-left-width: 0; - border-right-color: #fff; } -.popover.bottom > .arrow { - left: 50%; - margin-left: -11px; - border-top-width: 0; - border-bottom-color: transparent; - border-bottom-color: fadein(transparent, 12%); - top: -11px; } - .popover.bottom > .arrow:after { - content: " "; - top: 1px; - margin-left: -10px; - border-top-width: 0; - border-bottom-color: #fff; } -.popover.left > .arrow { - top: 50%; - right: -11px; - margin-top: -11px; - border-right-width: 0; - border-left-color: transparent; - border-left-color: fadein(transparent, 12%); } - .popover.left > .arrow:after { - content: " "; - right: 1px; - border-right-width: 0; - border-left-color: #fff; - bottom: -10px; } - -.carousel { - position: relative; } - -.carousel-inner { - position: relative; - overflow: hidden; - width: 100%; } - .carousel-inner > .item { - display: none; - position: relative; - -webkit-transition: 0.6s ease-in-out left; - -o-transition: 0.6s ease-in-out left; - transition: 0.6s ease-in-out left; } - .carousel-inner > .item > img, - .carousel-inner > .item > a > img { - display: block; - max-width: 100%; - height: auto; - line-height: 1; } - @media all and (transform-3d), (-webkit-transform-3d) { - .carousel-inner > .item { - -webkit-transition: -webkit-transform 0.6s ease-in-out; - -moz-transition: -moz-transform 0.6s ease-in-out; - -o-transition: -o-transform 0.6s ease-in-out; - transition: transform 0.6s ease-in-out; - -webkit-backface-visibility: hidden; - -moz-backface-visibility: hidden; - backface-visibility: hidden; - -webkit-perspective: 1000px; - -moz-perspective: 1000px; - perspective: 1000px; } - .carousel-inner > .item.next, .carousel-inner > .item.active.right { - -webkit-transform: translate3d(100%, 0, 0); - transform: translate3d(100%, 0, 0); - left: 0; } - .carousel-inner > .item.prev, .carousel-inner > .item.active.left { - -webkit-transform: translate3d(-100%, 0, 0); - transform: translate3d(-100%, 0, 0); - left: 0; } - .carousel-inner > .item.next.left, .carousel-inner > .item.prev.right, .carousel-inner > .item.active { - -webkit-transform: translate3d(0, 0, 0); - transform: translate3d(0, 0, 0); - left: 0; } } - .carousel-inner > .active, - .carousel-inner > .next, - .carousel-inner > .prev { - display: block; } - .carousel-inner > .active { - left: 0; } - .carousel-inner > .next, - .carousel-inner > .prev { - position: absolute; - top: 0; - width: 100%; } - .carousel-inner > .next { - left: 100%; } - .carousel-inner > .prev { - left: -100%; } - .carousel-inner > .next.left, - .carousel-inner > .prev.right { - left: 0; } - .carousel-inner > .active.left { - left: -100%; } - .carousel-inner > .active.right { - left: 100%; } - -.carousel-control { - position: absolute; - top: 0; - left: 0; - bottom: 0; - width: 15%; - opacity: 0.5; - filter: alpha(opacity=50); - font-size: 20px; - color: #fff; - text-align: center; - text-shadow: 0 1px 2px rgba(0, 0, 0, 0.6); - background-color: transparent; } - .carousel-control.left { - background-image: -webkit-linear-gradient(left, rgba(0, 0, 0, 0.5) 0%, rgba(0, 0, 0, 0.0001) 100%); - background-image: -o-linear-gradient(left, rgba(0, 0, 0, 0.5) 0%, rgba(0, 0, 0, 0.0001) 100%); - background-image: linear-gradient(to right, rgba(0, 0, 0, 0.5) 0%, rgba(0, 0, 0, 0.0001) 100%); - background-repeat: repeat-x; - filter: progid:DXImageTransform.Microsoft.gradient(startColorstr='#80000000', endColorstr='#00000000', GradientType=1); } - .carousel-control.right { - left: auto; - right: 0; - background-image: -webkit-linear-gradient(left, rgba(0, 0, 0, 0.0001) 0%, rgba(0, 0, 0, 0.5) 100%); - background-image: -o-linear-gradient(left, rgba(0, 0, 0, 0.0001) 0%, rgba(0, 0, 0, 0.5) 100%); - background-image: linear-gradient(to right, rgba(0, 0, 0, 0.0001) 0%, rgba(0, 0, 0, 0.5) 100%); - background-repeat: repeat-x; - filter: progid:DXImageTransform.Microsoft.gradient(startColorstr='#00000000', endColorstr='#80000000', GradientType=1); } - .carousel-control:hover, .carousel-control:focus { - outline: 0; - color: #fff; - text-decoration: none; - opacity: 0.9; - filter: alpha(opacity=90); } - .carousel-control .icon-prev, - .carousel-control .icon-next, - .carousel-control .glyphicon-chevron-left, - .carousel-control .glyphicon-chevron-right { - position: absolute; - top: 50%; - margin-top: -10px; - z-index: 5; - display: inline-block; } - .carousel-control .icon-prev, - .carousel-control .glyphicon-chevron-left { - left: 50%; - margin-left: -10px; } - .carousel-control .icon-next, - .carousel-control .glyphicon-chevron-right { - right: 50%; - margin-right: -10px; } - .carousel-control .icon-prev, - .carousel-control .icon-next { - width: 20px; - height: 20px; - line-height: 1; - font-family: serif; } - .carousel-control .icon-prev:before { - content: '\2039'; } - .carousel-control .icon-next:before { - content: '\203a'; } - -.carousel-indicators { - position: absolute; - bottom: 10px; - left: 50%; - z-index: 15; - width: 60%; - margin-left: -30%; - padding-left: 0; - list-style: none; - text-align: center; } - .carousel-indicators li { - display: inline-block; - width: 10px; - height: 10px; - margin: 1px; - text-indent: -999px; - border: 1px solid #fff; - border-radius: 10px; - cursor: pointer; - background-color: #000 \9; - background-color: transparent; } - .carousel-indicators .active { - margin: 0; - width: 12px; - height: 12px; - background-color: #fff; } - -.carousel-caption { - position: absolute; - left: 15%; - right: 15%; - bottom: 20px; - z-index: 10; - padding-top: 20px; - padding-bottom: 20px; - color: #fff; - text-align: center; - text-shadow: 0 1px 2px rgba(0, 0, 0, 0.6); } - .carousel-caption .btn { - text-shadow: none; } - -@media screen and (min-width: 768px) { - .carousel-control .glyphicon-chevron-left, - .carousel-control .glyphicon-chevron-right, - .carousel-control .icon-prev, - .carousel-control .icon-next { - width: 30px; - height: 30px; - margin-top: -10px; - font-size: 30px; } - .carousel-control .glyphicon-chevron-left, - .carousel-control .icon-prev { - margin-left: -10px; } - .carousel-control .glyphicon-chevron-right, - .carousel-control .icon-next { - margin-right: -10px; } - - .carousel-caption { - left: 20%; - right: 20%; - padding-bottom: 30px; } - - .carousel-indicators { - bottom: 20px; } } -.clearfix:before, .clearfix:after { - content: " "; - display: table; } -.clearfix:after { - clear: both; } - -.center-block { - display: block; - margin-left: auto; - margin-right: auto; } - -.pull-right { - float: right !important; } - -.pull-left { - float: left !important; } - -.hide { - display: none !important; } - -.show { - display: block !important; } - -.invisible { - visibility: hidden; } - -.text-hide { - font: 0/0 a; - color: transparent; - text-shadow: none; - background-color: transparent; - border: 0; } - -.hidden { - display: none !important; } - -.affix { - position: fixed; } - -@-ms-viewport { - width: device-width; } -.visible-xs { - display: none !important; } - -.visible-sm { - display: none !important; } - -.visible-md { - display: none !important; } - -.visible-lg { - display: none !important; } - -.visible-xs-block, -.visible-xs-inline, -.visible-xs-inline-block, -.visible-sm-block, -.visible-sm-inline, -.visible-sm-inline-block, -.visible-md-block, -.visible-md-inline, -.visible-md-inline-block, -.visible-lg-block, -.visible-lg-inline, -.visible-lg-inline-block { - display: none !important; } - -@media (max-width: 767px) { - .visible-xs { - display: block !important; } - - table.visible-xs { - display: table !important; } - - tr.visible-xs { - display: table-row !important; } - - th.visible-xs, - td.visible-xs { - display: table-cell !important; } } -@media (max-width: 767px) { - .visible-xs-block { - display: block !important; } } - -@media (max-width: 767px) { - .visible-xs-inline { - display: inline !important; } } - -@media (max-width: 767px) { - .visible-xs-inline-block { - display: inline-block !important; } } - -@media (min-width: 768px) and (max-width: 991px) { - .visible-sm { - display: block !important; } - - table.visible-sm { - display: table !important; } - - tr.visible-sm { - display: table-row !important; } - - th.visible-sm, - td.visible-sm { - display: table-cell !important; } } -@media (min-width: 768px) and (max-width: 991px) { - .visible-sm-block { - display: block !important; } } - -@media (min-width: 768px) and (max-width: 991px) { - .visible-sm-inline { - display: inline !important; } } - -@media (min-width: 768px) and (max-width: 991px) { - .visible-sm-inline-block { - display: inline-block !important; } } - -@media (min-width: 992px) and (max-width: 1199px) { - .visible-md { - display: block !important; } - - table.visible-md { - display: table !important; } - - tr.visible-md { - display: table-row !important; } - - th.visible-md, - td.visible-md { - display: table-cell !important; } } -@media (min-width: 992px) and (max-width: 1199px) { - .visible-md-block { - display: block !important; } } - -@media (min-width: 992px) and (max-width: 1199px) { - .visible-md-inline { - display: inline !important; } } - -@media (min-width: 992px) and (max-width: 1199px) { - .visible-md-inline-block { - display: inline-block !important; } } - -@media (min-width: 1200px) { - .visible-lg { - display: block !important; } - - table.visible-lg { - display: table !important; } - - tr.visible-lg { - display: table-row !important; } - - th.visible-lg, - td.visible-lg { - display: table-cell !important; } } -@media (min-width: 1200px) { - .visible-lg-block { - display: block !important; } } - -@media (min-width: 1200px) { - .visible-lg-inline { - display: inline !important; } } - -@media (min-width: 1200px) { - .visible-lg-inline-block { - display: inline-block !important; } } - -@media (max-width: 767px) { - .hidden-xs { - display: none !important; } } -@media (min-width: 768px) and (max-width: 991px) { - .hidden-sm { - display: none !important; } } -@media (min-width: 992px) and (max-width: 1199px) { - .hidden-md { - display: none !important; } } -@media (min-width: 1200px) { - .hidden-lg { - display: none !important; } } -.visible-print { - display: none !important; } - -@media print { - .visible-print { - display: block !important; } - - table.visible-print { - display: table !important; } - - tr.visible-print { - display: table-row !important; } - - th.visible-print, - td.visible-print { - display: table-cell !important; } } -.visible-print-block { - display: none !important; } - @media print { - .visible-print-block { - display: block !important; } } - -.visible-print-inline { - display: none !important; } - @media print { - .visible-print-inline { - display: inline !important; } } - -.visible-print-inline-block { - display: none !important; } - @media print { - .visible-print-inline-block { - display: inline-block !important; } } - -@media print { - .hidden-print { - display: none !important; } } -/*! - * tidyverse theme - * Copyright 2016 RStudio, Inc. - */ -.navbar { - border: none; - -webkit-box-shadow: 0 3px 15px 0px rgba(0, 0, 0, 0.1); - box-shadow: 0 3px 15px 0px rgba(0, 0, 0, 0.1); - min-height: 50px; - padding: 5px 0; } - .navbar-brand { - font-family: "Source Code Pro", Menlo, Monaco, Consolas, "Courier New", monospace; - font-weight: normal; - font-size: 32px; - padding: 0 0 0 54px; - height: 50px; - line-height: 50px; - background-image: url(../logo.png); - background-size: 32px auto; - background-repeat: no-repeat; - background-position: 15px center; } - .navbar-nav li a { - padding-top: 10px; - padding-bottom: 0; - line-height: inherit; } - .navbar-inverse .navbar-form input[type=text], - .navbar-inverse .navbar-form input[type=password] { - color: #fff; - -webkit-box-shadow: inset 0 -1px 0 #d8e8f6; - box-shadow: inset 0 -1px 0 #d8e8f6; } - .navbar-inverse .navbar-form input[type=text]::-moz-placeholder, - .navbar-inverse .navbar-form input[type=password]::-moz-placeholder { - color: #d8e8f6; - opacity: 1; } - .navbar-inverse .navbar-form input[type=text]:-ms-input-placeholder, - .navbar-inverse .navbar-form input[type=password]:-ms-input-placeholder { - color: #d8e8f6; } - .navbar-inverse .navbar-form input[type=text]::-webkit-input-placeholder, - .navbar-inverse .navbar-form input[type=password]::-webkit-input-placeholder { - color: #d8e8f6; } - .navbar-inverse .navbar-form input[type=text]:focus, - .navbar-inverse .navbar-form input[type=password]:focus { - -webkit-box-shadow: inset 0 -2px 0 #fff; - box-shadow: inset 0 -2px 0 #fff; } - -.btn-default:focus { - background-color: #fff; } -.btn-default:hover, .btn-default:active:hover { - background-color: #f0f0f0; } -.btn-default:active { - -webkit-box-shadow: 2px 2px 4px rgba(0, 0, 0, 0.4); - box-shadow: 2px 2px 4px rgba(0, 0, 0, 0.4); } - -.btn-primary:focus { - background-color: #5a9ddb; } -.btn-primary:hover, .btn-primary:active:hover { - background-color: #418ed6; } -.btn-primary:active { - -webkit-box-shadow: 2px 2px 4px rgba(0, 0, 0, 0.4); - box-shadow: 2px 2px 4px rgba(0, 0, 0, 0.4); } - -.btn-success:focus { - background-color: #4CAF50; } -.btn-success:hover, .btn-success:active:hover { - background-color: #439a46; } -.btn-success:active { - -webkit-box-shadow: 2px 2px 4px rgba(0, 0, 0, 0.4); - box-shadow: 2px 2px 4px rgba(0, 0, 0, 0.4); } - -.btn-info:focus { - background-color: #9C27B0; } -.btn-info:hover, .btn-info:active:hover { - background-color: #862197; } -.btn-info:active { - -webkit-box-shadow: 2px 2px 4px rgba(0, 0, 0, 0.4); - box-shadow: 2px 2px 4px rgba(0, 0, 0, 0.4); } - -.btn-warning:focus { - background-color: #ff9800; } -.btn-warning:hover, .btn-warning:active:hover { - background-color: #e08600; } -.btn-warning:active { - -webkit-box-shadow: 2px 2px 4px rgba(0, 0, 0, 0.4); - box-shadow: 2px 2px 4px rgba(0, 0, 0, 0.4); } - -.btn-danger:focus { - background-color: #e51c23; } -.btn-danger:hover, .btn-danger:active:hover { - background-color: #cb171e; } -.btn-danger:active { - -webkit-box-shadow: 2px 2px 4px rgba(0, 0, 0, 0.4); - box-shadow: 2px 2px 4px rgba(0, 0, 0, 0.4); } - -.btn-link:focus { - background-color: #fff; } -.btn-link:hover, .btn-link:active:hover { - background-color: #f0f0f0; } -.btn-link:active { - -webkit-box-shadow: 2px 2px 4px rgba(0, 0, 0, 0.4); - box-shadow: 2px 2px 4px rgba(0, 0, 0, 0.4); } - -.btn { - text-transform: uppercase; - border: none; - -webkit-box-shadow: 1px 1px 4px rgba(0, 0, 0, 0.4); - box-shadow: 1px 1px 4px rgba(0, 0, 0, 0.4); - -webkit-transition: all 0.4s; - -o-transition: all 0.4s; - transition: all 0.4s; - position: relative; } - .btn:after { - content: ""; - display: block; - position: absolute; - width: 100%; - height: 100%; - top: 0; - left: 0; - background-image: -webkit-radial-gradient(circle, #000 10%, transparent 10.01%); - background-image: radial-gradient(circle, #000 10%, transparent 10.01%); - background-repeat: no-repeat; - background-size: 1000% 1000%; - background-position: 50%; - opacity: 0; - pointer-events: none; - transition: background .5s, opacity 1s; } - .btn:active:after { - background-size: 0% 0%; - opacity: .2; - transition: 0s; } - .btn-link { - border-radius: 3px; - -webkit-box-shadow: none; - box-shadow: none; - color: #444; } - .btn-link:hover, .btn-link:focus { - -webkit-box-shadow: none; - box-shadow: none; - color: #444; - text-decoration: none; } - .btn-default.disabled { - background-color: rgba(0, 0, 0, 0.1); - color: rgba(0, 0, 0, 0.4); - opacity: 1; } - -.btn-group .btn + .btn, -.btn-group .btn + .btn-group, -.btn-group .btn-group + .btn, -.btn-group .btn-group + .btn-group { - margin-left: 0; } -.btn-group-vertical > .btn + .btn, -.btn-group-vertical > .btn + .btn-group, -.btn-group-vertical > .btn-group + .btn, -.btn-group-vertical > .btn-group + .btn-group { - margin-top: 0; } - -body { - -webkit-font-smoothing: antialiased; - letter-spacing: .1px; } - -p { - margin: 0 0 1em; } - -input, -button { - -webkit-font-smoothing: antialiased; - letter-spacing: .1px; } - -a { - -webkit-transition: all 0.25s; - -o-transition: all 0.25s; - transition: all 0.25s; } - -.table-hover > tbody > tr, -.table-hover > tbody > tr > th, -.table-hover > tbody > tr > td { - -webkit-transition: all 0.2s; - -o-transition: all 0.2s; - transition: all 0.2s; } - -label { - font-weight: normal; } - -textarea, -textarea.form-control, -input.form-control, -input[type=text], -input[type=password], -input[type=email], -input[type=number], -[type=text].form-control, -[type=password].form-control, -[type=email].form-control, -[type=tel].form-control, -[contenteditable].form-control { - padding: 0; - border: none; - border-radius: 0; - -webkit-appearance: none; - -webkit-box-shadow: inset 0 -1px 0 #ddd; - box-shadow: inset 0 -1px 0 #ddd; - font-size: 16px; } - textarea:focus, - textarea.form-control:focus, - input.form-control:focus, - input[type=text]:focus, - input[type=password]:focus, - input[type=email]:focus, - input[type=number]:focus, - [type=text].form-control:focus, - [type=password].form-control:focus, - [type=email].form-control:focus, - [type=tel].form-control:focus, - [contenteditable].form-control:focus { - -webkit-box-shadow: inset 0 -2px 0 #5a9ddb; - box-shadow: inset 0 -2px 0 #5a9ddb; } - textarea[disabled], textarea[readonly], - textarea.form-control[disabled], - textarea.form-control[readonly], - input.form-control[disabled], - input.form-control[readonly], - input[type=text][disabled], - input[type=text][readonly], - input[type=password][disabled], - input[type=password][readonly], - input[type=email][disabled], - input[type=email][readonly], - input[type=number][disabled], - input[type=number][readonly], - [type=text].form-control[disabled], - [type=text].form-control[readonly], - [type=password].form-control[disabled], - [type=password].form-control[readonly], - [type=email].form-control[disabled], - [type=email].form-control[readonly], - [type=tel].form-control[disabled], - [type=tel].form-control[readonly], - [contenteditable].form-control[disabled], - [contenteditable].form-control[readonly] { - -webkit-box-shadow: none; - box-shadow: none; - border-bottom: 1px dotted #ddd; } - textarea.input-sm, .input-group-sm > textarea.form-control, - .input-group-sm > textarea.input-group-addon, - .input-group-sm > .input-group-btn > textarea.btn, - textarea.form-control.input-sm, - .input-group-sm > textarea.form-control, - .input-group-sm > .input-group-btn > textarea.form-control.btn, - input.form-control.input-sm, - .input-group-sm > input.form-control, - .input-group-sm > .input-group-btn > input.form-control.btn, - input[type=text].input-sm, - .input-group-sm > input[type=text].form-control, - .input-group-sm > input[type=text].input-group-addon, - .input-group-sm > .input-group-btn > input[type=text].btn, - input[type=password].input-sm, - .input-group-sm > input[type=password].form-control, - .input-group-sm > input[type=password].input-group-addon, - .input-group-sm > .input-group-btn > input[type=password].btn, - input[type=email].input-sm, - .input-group-sm > input[type=email].form-control, - .input-group-sm > input[type=email].input-group-addon, - .input-group-sm > .input-group-btn > input[type=email].btn, - input[type=number].input-sm, - .input-group-sm > input[type=number].form-control, - .input-group-sm > input[type=number].input-group-addon, - .input-group-sm > .input-group-btn > input[type=number].btn, - [type=text].form-control.input-sm, - .input-group-sm > [type=text].form-control, - .input-group-sm > .input-group-btn > [type=text].form-control.btn, - [type=password].form-control.input-sm, - .input-group-sm > [type=password].form-control, - .input-group-sm > .input-group-btn > [type=password].form-control.btn, - [type=email].form-control.input-sm, - .input-group-sm > [type=email].form-control, - .input-group-sm > .input-group-btn > [type=email].form-control.btn, - [type=tel].form-control.input-sm, - .input-group-sm > [type=tel].form-control, - .input-group-sm > .input-group-btn > [type=tel].form-control.btn, - [contenteditable].form-control.input-sm, - .input-group-sm > [contenteditable].form-control, - .input-group-sm > .input-group-btn > [contenteditable].form-control.btn { - font-size: 13px; } - textarea.input-lg, .input-group-lg > textarea.form-control, - .input-group-lg > textarea.input-group-addon, - .input-group-lg > .input-group-btn > textarea.btn, - textarea.form-control.input-lg, - .input-group-lg > textarea.form-control, - .input-group-lg > .input-group-btn > textarea.form-control.btn, - input.form-control.input-lg, - .input-group-lg > input.form-control, - .input-group-lg > .input-group-btn > input.form-control.btn, - input[type=text].input-lg, - .input-group-lg > input[type=text].form-control, - .input-group-lg > 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0 1px 4px rgba(0, 0, 0, 0.3); - box-shadow: 0 1px 4px rgba(0, 0, 0, 0.3); } - -.carousel-caption h1, .carousel-caption h2, .carousel-caption h3, .carousel-caption h4, .carousel-caption h5, .carousel-caption h6 { - color: inherit; } - -/*# sourceMappingURL=tidyverse.css.map */ diff --git a/docs/tocBullet.svg b/docs/tocBullet.svg deleted file mode 100644 index 29abb51..0000000 --- a/docs/tocBullet.svg +++ /dev/null @@ -1,11 +0,0 @@ - - - - - - - diff --git a/man/ConcTime.Rd b/man/ConcTime.Rd deleted file mode 100644 index 61ee09b..0000000 --- a/man/ConcTime.Rd +++ /dev/null @@ -1,28 +0,0 @@ -% Generated by roxygen2: do not edit by hand -% Please edit documentation in R/ConcTime.R -\name{ConcTime} -\alias{ConcTime} -\title{Create a dataset of the concentration-time curve} -\usage{ -ConcTime(Weight, Dose, N = 20) -} -\arguments{ -\item{Weight}{Body weight (kg)} - -\item{Dose}{Dose of single caffeine (mg)} - -\item{N}{The number of simulated subjects} -} -\value{ -The dataset of concentration and time of simulated subjects -} -\description{ -\code{ConcTime} will create a dataset of the concentration-time curve -} -\examples{ -ConcTime(Weight = 20, Dose = 200, N = 20) -ConcTime(20, 200) -} -\seealso{ -\url{http://asancpt.github.io/CaffeineEdison} -} diff --git a/man/UnitTable.Rd b/man/UnitTable.Rd index 92545ed..b78d722 100644 --- a/man/UnitTable.Rd +++ b/man/UnitTable.Rd @@ -9,13 +9,13 @@ \item{Parameters}{Abbreviated pharmacokinetic parameters} \item{Parameter}{Pharmacokinetic parameters in full name} }} -\source{ -\url{http://asancpt.github.io/CaffeineEdison} -} \usage{ UnitTable } \description{ A dataset containing information regarding unit data of pharmacokinetic parameters } +\seealso{ +\url{https://asancpt.github.io/caffsim} +} \keyword{datasets} diff --git a/man/caffConcTime.Rd b/man/caffConcTime.Rd new file mode 100644 index 0000000..33acf1c --- /dev/null +++ b/man/caffConcTime.Rd @@ -0,0 +1,28 @@ +% Generated by roxygen2: do not edit by hand +% Please edit documentation in R/ConcTime.R +\name{caffConcTime} +\alias{caffConcTime} +\title{Create a dataset of the concentration-time curve of single oral administration of caffeine} +\usage{ +caffConcTime(Weight, Dose, N = 20) +} +\arguments{ +\item{Weight}{Body weight (kg)} + +\item{Dose}{Dose of single caffeine (mg)} + +\item{N}{The number of simulated subjects} +} +\value{ +The dataset of concentration and time of simulated subjects +} +\description{ +\code{caffConcTime} will create a dataset of the concentration-time curve +} +\examples{ +caffConcTime(Weight = 20, Dose = 200, N = 20) +caffConcTime(20, 200) +} +\seealso{ +\url{https://asancpt.github.io/caffsim} +} diff --git a/man/ConcTimeMulti.Rd b/man/caffConcTimeMulti.Rd similarity index 56% rename from man/ConcTimeMulti.Rd rename to man/caffConcTimeMulti.Rd index ce2a897..2275085 100644 --- a/man/ConcTimeMulti.Rd +++ b/man/caffConcTimeMulti.Rd @@ -1,10 +1,10 @@ % Generated by roxygen2: do not edit by hand % Please edit documentation in R/ConcTime.R -\name{ConcTimeMulti} -\alias{ConcTimeMulti} -\title{Create a dataset of the concentration-time curve of multiple dosing} +\name{caffConcTimeMulti} +\alias{caffConcTimeMulti} +\title{Create a dataset of the concentration-time curve of multiple dosing of caffeine} \usage{ -ConcTimeMulti(Weight, Dose, N = 20, Tau = 8, Repeat = 4) +caffConcTimeMulti(Weight, Dose, N = 20, Tau = 8, Repeat = 4) } \arguments{ \item{Weight}{Body weight (kg)} @@ -21,12 +21,12 @@ ConcTimeMulti(Weight, Dose, N = 20, Tau = 8, Repeat = 4) The dataset of concentration and time of simulated subjects of multiple dosing } \description{ -\code{ConcTimeMulti} will create a dataset of the concentration-time curve of multiple dosing +\code{caffConcTimeMulti} will create a dataset of the concentration-time curve of multiple oral administrations of caffeine } \examples{ -ConcTimeMulti(Weight = 20, Dose = 200, N = 20, Tau = 8, Repeat = 4) -ConcTimeMulti(20, 200) +caffConcTimeMulti(Weight = 20, Dose = 200, N = 20, Tau = 8, Repeat = 4) +caffConcTimeMulti(20, 200) } \seealso{ -\url{http://asancpt.github.io/CaffeineEdison} +\url{https://asancpt.github.io/caffsim} } diff --git a/man/Dataset.Rd b/man/caffDataset.Rd similarity index 63% rename from man/Dataset.Rd rename to man/caffDataset.Rd index bd46504..366523e 100644 --- a/man/Dataset.Rd +++ b/man/caffDataset.Rd @@ -1,10 +1,10 @@ % Generated by roxygen2: do not edit by hand % Please edit documentation in R/Dataset.R -\name{Dataset} -\alias{Dataset} +\name{caffDataset} +\alias{caffDataset} \title{Create a dataset for simulation of single dose of caffeine} \usage{ -Dataset(Weight, Dose, N = 20) +caffDataset(Weight, Dose, N = 20) } \arguments{ \item{Weight}{Body weight (kg)} @@ -17,12 +17,12 @@ Dataset(Weight, Dose, N = 20) The dataset of pharmacokinetic parameters of subjects after single caffeine dose following multivariate normal } \description{ -\code{Dataset} will create a dataset for simulation of single dose of caffeine +\code{caffDataset} will create a dataset for simulation of single dose of caffeine } \examples{ -Dataset(Weight = 20, Dose = 200, N = 20) -Dataset(20,500) +caffDataset(Weight = 20, Dose = 200, N = 20) +caffDataset(20,500) } \seealso{ -\url{http://asancpt.github.io/CaffeineEdison} +\url{https://asancpt.github.io/caffsim} } diff --git a/man/DatasetMulti.Rd b/man/caffDatasetMulti.Rd similarity index 62% rename from man/DatasetMulti.Rd rename to man/caffDatasetMulti.Rd index 60a81e9..9e79b19 100644 --- a/man/DatasetMulti.Rd +++ b/man/caffDatasetMulti.Rd @@ -1,10 +1,10 @@ % Generated by roxygen2: do not edit by hand % Please edit documentation in R/Dataset.R -\name{DatasetMulti} -\alias{DatasetMulti} +\name{caffDatasetMulti} +\alias{caffDatasetMulti} \title{Create a dataset for simulation of multiple dose of caffeine} \usage{ -DatasetMulti(Weight, Dose, N = 20, Tau = 24) +caffDatasetMulti(Weight, Dose, N = 20, Tau = 24) } \arguments{ \item{Weight}{Body weight (kg)} @@ -19,12 +19,12 @@ DatasetMulti(Weight, Dose, N = 20, Tau = 24) The dataset of pharmacokinetic parameters of subjects after multiple caffeine dose following multivariate normal } \description{ -\code{DatasetMulti} will create a dataset for simulation of multiple dose of caffeine +\code{caffDatasetMulti} will create a dataset for simulation of multiple dose of caffeine } \examples{ -DatasetMulti(Weight = 20, Dose = 200, N = 20, Tau = 8) -DatasetMulti(20,500) +caffDatasetMulti(Weight = 20, Dose = 200, N = 20, Tau = 8) +caffDatasetMulti(20,500) } \seealso{ -\url{http://asancpt.github.io/CaffeineEdison} +\url{https://asancpt.github.io/caffsim} } diff --git a/man/Plot.Rd b/man/caffPlot.Rd similarity index 73% rename from man/Plot.Rd rename to man/caffPlot.Rd index f5f66bd..86db193 100644 --- a/man/Plot.Rd +++ b/man/caffPlot.Rd @@ -1,15 +1,15 @@ % Generated by roxygen2: do not edit by hand % Please edit documentation in R/Plot.R -\name{Plot} -\alias{Plot} +\name{caffPlot} +\alias{caffPlot} \title{Create concentration-time curve after single dose of caffeine} \usage{ -Plot(ConcTime, log = FALSE) +caffPlot(caffConcTime, log = FALSE) } \arguments{ -\item{ConcTime}{Concentration-time dataset having column names Subject, Time, and Conc (case-sensitive)} - \item{log}{y axis log} + +\item{ConcTime}{Concentration-time dataset having column names Subject, Time, and Conc (case-sensitive)} } \value{ The concentration-time curve @@ -18,8 +18,8 @@ The concentration-time curve \code{Plot} will create concentration-time curve after single dose of caffeine } \examples{ -Plot(ConcTime(Weight = 20, Dose = 200, N = 20)) +caffPlot(caffConcTime(Weight = 20, Dose = 200, N = 20)) } \seealso{ -\url{http://asancpt.github.io/CaffeineEdison} +\url{https://asancpt.github.io/caffsim} } diff --git a/man/PlotMulti.Rd b/man/caffPlotMulti.Rd similarity index 69% rename from man/PlotMulti.Rd rename to man/caffPlotMulti.Rd index 913e739..07fd13c 100644 --- a/man/PlotMulti.Rd +++ b/man/caffPlotMulti.Rd @@ -1,15 +1,15 @@ % Generated by roxygen2: do not edit by hand % Please edit documentation in R/Plot.R -\name{PlotMulti} -\alias{PlotMulti} +\name{caffPlotMulti} +\alias{caffPlotMulti} \title{Create concentration-time curve after multiple doses of caffeine} \usage{ -PlotMulti(ConcTimeMulti, log = FALSE) +caffPlotMulti(caffConcTimeMulti, log = FALSE) } \arguments{ -\item{ConcTimeMulti}{Concentration-time dataset having column names Subject, Time, and Conc (case-sensitive)} - \item{log}{y axis log} + +\item{ConcTimeMulti}{Concentration-time dataset having column names Subject, Time, and Conc (case-sensitive)} } \value{ The concentration-time curve @@ -18,8 +18,8 @@ The concentration-time curve \code{PlotMulti} will create concentration-time curve after multiple doses of caffeine } \examples{ -PlotMulti(ConcTimeMulti(Weight = 20, Dose = 200, N = 20, Tau = 8, Repeat = 4)) +caffPlotMulti(ConcTimeMulti(Weight = 20, Dose = 200, N = 20, Tau = 8, Repeat = 4)) } \seealso{ -\url{http://asancpt.github.io/CaffeineEdison} +\url{https://asancpt.github.io/caffsim} } diff --git a/pkgdown.sh b/pkgdown.sh deleted file mode 100644 index a57a545..0000000 --- a/pkgdown.sh +++ /dev/null @@ -1,3 +0,0 @@ -Rscript -e "Sys.setlocale('LC_ALL', 'C'); pkgdown::build_site()" - - diff --git a/rd2pdf.sh b/rd2pdf.sh deleted file mode 100644 index 4a1daf2..0000000 --- a/rd2pdf.sh +++ /dev/null @@ -1,3 +0,0 @@ -rm caffsim.pdf -R CMD rd2pdf ../caffsim -