diff --git a/README.md b/README.md
index 2eb697e39..ccc639c77 100644
--- a/README.md
+++ b/README.md
@@ -35,4 +35,7 @@ This project is licensed under the Apache-2.0 License.
 ## Notices
 
 ### Python Version Support
-This project ensures compatibility with the following supported Python versions: 3.8, 3.9, 3.10, 3.11
\ No newline at end of file
+This project ensures compatibility with the following supported Python versions: 3.8, 3.9, 3.10, 3.11
+
+### Note on Amazon CloudWatch Application Signals
+[Amazon CloudWatch Application Signals](https://docs.aws.amazon.com/AmazonCloudWatch/latest/monitoring/CloudWatch-Application-Monitoring-Sections.html) components are designed to seamlessly work with all library instrumentations offered by [OpenTelemetry Python auto-instrumentation](https://github.com/open-telemetry/opentelemetry-python-contrib/blob/main/instrumentation/README.md). While upstream OpenTelemetry Python instrumentations are in beta, Application Signals components are stable, production ready and have also been tested for popular libraries/frameworks such as [Django, Boto3, and others](https://github.com/aws-observability/aws-otel-python-instrumentation/tree/main/contract-tests/images/applications). We will prioritize backward compatibility for Application Signals components, striving to ensure that they remain functional even in the face of potential breaking changes introduced by OpenTelemetry upstream libraries. Please raise any tickets/issues in case you notice Application Signals doesn't work for a particular OpenTelemetry supported library.