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Reproduce Decipher paper figures

This repository contains the notebooks used to produce the figures of the Decipher paper. The Decipher code used in these notebook is available at:

  1. https://github.com/azizilab/decipher at commit: 63b7d25c44bf1bbfa65ca7865e41b6c9b0abcf07.
  2. https://github.com/azizilab/decipher/releases/tag/reproducibility at tag: reproducibility.
  3. included in this repo in the decipher_code directory.

For using Decipher, we recommend using the latest version at https://github.com/azizilab/decipher. It is more documented and has more features.

Figure 1

  • simulated_data.ipynb

Figure 2

  • simulation/
    • Run simulation.py, then generate_figures.py

Figure 3

  • Figure_3_PDAC.ipynb
  • pdac_scvi.ipynb

Figure 4

  • EDF 1.ipynb
  • analysis-aml1.ipynb
  • comparison-aml1-scvi-decipher.ipynb
  • ext-fig-adjustments.ipynb

Figure 5

  • analysis-aml1.ipynb
  • temporal_tf.ipynb

Figure 6

  • temporal_tf.ipynb
  • cohort_comparison.ipynb

Figure 7

Supplementary Figure 1

  • Figure_3_PDAC.ipynb
  • pdac_scvi.ipynb

Supplementary Figure 2

  • EDF 1.ipynb
  • mutation_call.ipynb
  • 00_decipher AML cohort.ipynb

Supplementary Figure 3

  • ext-fig-adjustments.ipynb

Supplementary Figure 4

  • benchmark/1-run-R-methods.ipynb
  • benchmark/2-run-Python-methods.ipynb
  • benchmark/3-evaluate-metric.ipynb

Supplementary Figure 5

  • ext-fig-adjustments.ipynb

Supplementary Figure 6

Supplementary Figure 7

  • temporal_tf.ipynb

Supplementary Figure 8

  • temporal_tf.ipynb

Supplementary Figure 9

  • temporal_tf.ipynb

Supplementary Figure 10

  • temporal_tf.ipynb

Supplementary Figure 11

  • cohort_comparison.ipynb
  • <additional notebook?>

SI Figure 1

SI Figure 2

  • RNA_ATAC_figures.ipynb
  • LIGER_from_ARCHR_merged-AML7.ipynb
  • Example_ArchR.ipynb

SI Figure 3

  • RNA_ATAC_figures.ipynb