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diff --git a/api.html b/api.html
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index 33ff04d..cb81f6f 100644
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diff --git a/database-structure.html b/database-structure.html
index 1ad0904..96ab27f 100644
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@@ -259,15 +259,15 @@ <h2><span class="header-section-number">4.2</span> Database schema<a href="datab
 <h2><span class="header-section-number">4.3</span> Variant ontology<a href="database-structure.html#variant-ontology" class="anchor-section" aria-label="Anchor link to header"></a></h2>
 <p>We use the “Variation Ontology” as ontology for the annotation of variation effects and mechanisms.
 Currently active terms are represented in following table. Initially we used 85 variant ontology terms. This was extended to include 11 additional terms for non-coding RNA variation. The column ‘use’ depicts the variant ontology terms used for our curation. The column ‘sort’ is used to display the most commonly used ontology terms first.</p>
-<div class="datatables html-widget html-fill-item" id="htmlwidget-a3f071d3723dae08bdb3" style="width:100%;height:auto;"></div>
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>VariO:0001<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0015\" target=\"_blank\" >VariO:0015<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0017\" target=\"_blank\" >VariO:0017<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0014\" target=\"_blank\" >VariO:0014<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0018\" target=\"_blank\" >VariO:0018<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0040\" target=\"_blank\" >VariO:0040<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0043\" target=\"_blank\" >VariO:0043<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0124\" target=\"_blank\" >VariO:0124<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0161\" target=\"_blank\" >VariO:0161<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0362\" target=\"_blank\" >VariO:0362<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0444\" target=\"_blank\" >VariO:0444<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0446\" target=\"_blank\" >VariO:0446<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0450\" target=\"_blank\" >VariO:0450<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0508\" target=\"_blank\" >VariO:0508<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0509\" target=\"_blank\" >VariO:0509<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0474\" target=\"_blank\" >VariO:0474<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0125\" target=\"_blank\" >VariO:0125<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0135\" target=\"_blank\" >VariO:0135<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0141\" target=\"_blank\" >VariO:0141<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0143\" target=\"_blank\" >VariO:0143<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0142\" target=\"_blank\" >VariO:0142<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0145\" target=\"_blank\" >VariO:0145<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0136\" target=\"_blank\" >VariO:0136<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0144\" target=\"_blank\" >VariO:0144<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0126\" target=\"_blank\" >VariO:0126<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0334\" target=\"_blank\" >VariO:0334<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0497\" target=\"_blank\" >VariO:0497<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0022\" target=\"_blank\" >VariO:0022<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0021\" target=\"_blank\" >VariO:0021<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0153\" target=\"_blank\" >VariO:0153<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0193\" target=\"_blank\" >VariO:0193<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0132\" target=\"_blank\" >VariO:0132<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0187\" target=\"_blank\" >VariO:0187<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0296\" target=\"_blank\" >VariO:0296<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0294\" target=\"_blank\" >VariO:0294<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0151\" target=\"_blank\" >VariO:0151<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0154\" target=\"_blank\" >VariO:0154<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0171\" target=\"_blank\" >VariO:0171<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0175\" target=\"_blank\" >VariO:0175<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0382\" target=\"_blank\" >VariO:0382<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0137\" target=\"_blank\" >VariO:0137<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0401\" target=\"_blank\" >VariO:0401<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0008\" target=\"_blank\" >VariO:0008<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0056\" target=\"_blank\" >VariO:0056<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0064\" target=\"_blank\" >VariO:0064<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0052\" target=\"_blank\" >VariO:0052<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0053\" target=\"_blank\" >VariO:0053<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0054\" target=\"_blank\" >VariO:0054<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0038\" target=\"_blank\" >VariO:0038<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0119\" target=\"_blank\" >VariO:0119<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0120\" target=\"_blank\" >VariO:0120<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0051\" target=\"_blank\" >VariO:0051<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0080\" target=\"_blank\" >VariO:0080<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0036\" target=\"_blank\" >VariO:0036<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0058\" target=\"_blank\" >VariO:0058<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0118\" target=\"_blank\" >VariO:0118<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0109\" target=\"_blank\" >VariO:0109<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0121\" target=\"_blank\" >VariO:0121<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0055\" target=\"_blank\" >VariO:0055<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0110\" target=\"_blank\" >VariO:0110<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0034\" target=\"_blank\" >VariO:0034<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0033\" target=\"_blank\" >VariO:0033<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0070\" target=\"_blank\" >VariO:0070<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0152\" target=\"_blank\" >VariO:0152<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0400\" target=\"_blank\" >VariO:0400<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0006\" target=\"_blank\" >VariO:0006<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0104\" target=\"_blank\" >VariO:0104<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0073\" target=\"_blank\" >VariO:0073<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0157\" target=\"_blank\" >VariO:0157<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0156\" target=\"_blank\" >VariO:0156<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0502\" target=\"_blank\" >VariO:0502<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0131\" target=\"_blank\" >VariO:0131<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0030\" target=\"_blank\" >VariO:0030<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0494\" target=\"_blank\" >VariO:0494<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0478\" target=\"_blank\" >VariO:0478<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0190\" target=\"_blank\" >VariO:0190<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0350\" target=\"_blank\" >VariO:0350<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0295\" target=\"_blank\" >VariO:0295<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0158\" target=\"_blank\" >VariO:0158<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0031\" target=\"_blank\" >VariO:0031<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0039\" target=\"_blank\" >VariO:0039<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0493\" target=\"_blank\" >VariO:0493<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0492\" target=\"_blank\" >VariO:0492<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0485\" target=\"_blank\" >VariO:0485<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0191\" target=\"_blank\" >VariO:0191<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0468\" target=\"_blank\" >VariO:0468<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0189\" target=\"_blank\" >VariO:0189<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0138\" target=\"_blank\" >VariO:0138<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0128\" target=\"_blank\" >VariO:0128<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0155\" target=\"_blank\" >VariO:0155<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0297\" target=\"_blank\" >VariO:0297<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0002\" target=\"_blank\" >VariO:0002<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0003\" target=\"_blank\" >VariO:0003<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0060\" target=\"_blank\" >VariO:0060<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0162\" target=\"_blank\" >VariO:0162<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0495\" target=\"_blank\" >VariO:0495<\/a>"],["variation","protein truncation","nonsynonymous variation","amino acid deletion","amino acid insertion","protein gain of function","protein loss of function","protein elongation","variation in intron","effect on RNA splicing","de novo variation","somatic variation","mitochondrial DNA affected","affected splice site","effect on mode of splicing","intron retention","C-terminal protein elongation","DNA chain variation","DNA deletion","DNA indel","DNA insertion","DNA inversion","DNA substitution","DNA translocation","N-terminal protein elongation","RNA splicing change","alternatively terminated mRNA","amino acid indel","amino acid substitution","chromatin variation","chromosomal deletion","chromosomal variation","copy number variation","disease associated","disease causing","effect on DNA repair","effect on DNA replication","effect on DNA tertiary structure","effect on DNA triple helix","effect on RNA secondary structure","effect on RNA tertiary structure","effect on amino acid transfer of RNA","effect on catalytic protein function","effect on enzyme reaction kinetics","effect on protein 3D structure","effect on protein abundance","effect on protein activity","effect on protein affinity","effect on protein aggregation","effect on protein binding site","effect on protein catalytic site","effect on protein degradation","effect on protein helix","effect on protein inclusion body formation","effect on protein interaction","effect on protein interaction site","effect on protein processing","effect on protein quaternary structure","effect on protein specificity","effect on protein splicing","effect on protein stability","effect on protein subcellular localization","effect on protein tertiary structure","effect on regulatory function of DNA","effect on regulatory function of RNA","effect on structural protein","effect on transmembrane polypeptide","effect to protein fold","epigenetic DNA methylation","epigenetic DNA modification","exon skipping","genomic variation","in-frame indel","long non-coding RNA","microRNA","mononucleotide expansion","non-protein coding RNA","not related to clinical phenotype","nucleosome positioning","out-of-frame indel","protein function change","ribosomal RNA","short non-coding RNA","spliceosomal RNA","tetranucleotide expansion","transfer RNA","trinucleotide expansion","variant","variation affecting DNA","variation affecting DNA structure","variation affecting RNA","variation affecting protein","variation affecting protein function","variation affecting protein structure","variation in exon","very long non-coding RNA"],["Alteration in DNA, RNA or protein.","Shortening of protein sequence from terminus.","mRNA variation leading to amino acid change in translated protein. The variant alters the codon so that it encodes another amino acid.","Removal of one or more continuous amino acids from protein.","Addition of one or more amino acids to protein sequence.","Effect of variation causing new or enhanced protein activity.","Effect of variation reducing or abolishing protein activity.","Variation prolonging protein chain at an end.","Variation located in intron.","Effect to process where introns in mRNA are cut away from exons.","Variation that has emerged in a germ cell on one of the parents or in the fertilized egg during early embryogenesis.","Variation that has its origin in a cell in soma.","Variation affecting DNA within mitochondria.","Type of variation affecting splice site.","Variation affecting the type of RNA splicing.","Inclusion intron sequence to mRNA.","Addition of one or more amino acids to protein C-terminus.","Variation at DNA chain.","Removal of one or more continuous nucleotides from DNA sequence.","A complex DNA variation consisting of both nucleotide insertion(s) and deletion(s).","Addition of one or more nucleotides between two adjacent nucleotides in the DNA sequence.","A continuous stretch of DNA sequence inserted to the same position in reverse orientation.","Substitution of a DNA nucleotide.","A continuous stretch of DNA sequence moved to a new position within a chromosome.","Addition of one or more amino acids to protein N-terminus.","Change to RNA splicing.","Variation causing alternative mRNA termination.","A complex protein variation consisting of both amino acid insertion(s) and deletion(s).","Substitution of an amino acid in protein.","Variation affecting chromatin.","Deletion of chromosomal region.","Variation at chromosomal level.","Increase or decrease of the number of copies of a chromosomal region. Sizes of copy number variations range from about 1 kilobase to several megabases.","Variation is disease related.","Variation is causative of disease.","Variation affecting the process of restoring DNA after damage.","Variation originating from semi conservative DNA strand synthesis. The template for replication is either DNA or RNA molecule.","Variation affecting DNA tertiary structure.","Variation affecting DNA helix formed of three strands.","Variation affecting RNA secondary structure.","Variation affecting RNA tertiary structure.","Variation affecting RNA function in amino acid transfer.","Effect of variation on catalytic function of protein.","Effect of variation to enzyme reaction kinetics.","Variation affecting protein three dimensional structure.","Variation affecting abundance of produced protein molecules.","Effect of variation on activity of protein.","Effect of variation on protein affinity to binding molecule(s).","Variation affecting protein aggregation tendency.","Variation affecting region on the surface of a protein that interacts with another molecule.","Variation affecting amino acid(s) in protein catalytic site.","Effect of variation on degradation of protein.","Variation affecting secondary structure conformation where the peptide backbone forms a coil.","Variation affecting the formation of particles of aggregated proteins.","Effect of variation on the interaction of protein with its partner.","Variation affecting ligand binding amino acid(s) in protein.","Variation affecting site of protein maturation by cleavage of peptide bond(s).","Variation affecting three dimensional structure of a protein complex.","Effect of variation on substrate binding specificity of protein.","Variation affecting post-translational removal of peptide sequences from within a protein sequence.","Effect of variation on stability of protein.","Effect of variation on the targeting of a protein within a cell or cellular compartment.","Variation affecting protein three dimensional structure.","Variation affecting regulatory function of DNA.","Variation affecting regulatory function of RNA.","Effect of variation on structural role of protein. Structural proteins are fibrous and involved in increasing rigidity and stiffness of biological systems.","Variation altering membrane spanning protein.","Variation affecting protein tertiary structure.","Inheritable cytosine or adenosine pyrimidine ring methylation regulating gene expression.","Hereditary variation of DNA not affecting primary sequence.","Variation where an exon is completele cleaved out from a mature transcript.","Variation of genomic level.","RNA indel not affecting reading frame after indel position.","Non-coding RNA longer than 200 nucleotides or base pairs.","Short non-coding RNA that binds to complementary region in mRNA and silences and regulates gene expression.","Tandem repetitive sequence consisting of one nucleotide type.","Variation affecting RNA not coding for protein.","Variation is not related to clinical phenotype.","Positioning of nucleosomes to DNA strand.","RNA indel containing a number of nucleotides not divisible by three and therefore causing change to reading frame.","Type of protein function affecting variation.","Non-coding RNA constituent of ribosome.","Non-coding RNA shorter than 200 nucleotides or base pairs.",null,"Tandem repetitive sequence consisting of four nucleotide units.","Transfer RNA involved in protein synthesis. Modiefied tRNA contains amino acid and carries it to ribosome.","Tandem repetitive sequence consisting of three nucleotide units.","A genetic character, organism or individual with a difference to reference state.","Effects of a variation on DNA level.","Variation affecting structure of DNA.","Effects of a variation on RNA level.","Effects of a variation on protein level.","Effect of variation on protein function.","Variation affecting structure of protein.","Variation located in exon.","Non-coding RNA longer than 10 kb."],[1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1],[1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null]],"container":"<table class=\"display\">\n  <thead>\n    <tr>\n      <th> <\/th>\n      <th>vario_id<\/th>\n      <th>vario_name<\/th>\n      <th>definition<\/th>\n      <th>use<\/th>\n      <th>sort<\/th>\n    <\/tr>\n  <\/thead>\n<\/table>","options":{"columnDefs":[{"className":"dt-right","targets":[4,5]},{"orderable":false,"targets":0},{"name":" ","targets":0},{"name":"vario_id","targets":1},{"name":"vario_name","targets":2},{"name":"definition","targets":3},{"name":"use","targets":4},{"name":"sort","targets":5}],"order":[],"autoWidth":false,"orderClasses":false,"orderCellsTop":true}},"evals":[],"jsHooks":[]}</script>
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>VariO:0001<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0015\" target=\"_blank\" >VariO:0015<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0017\" target=\"_blank\" >VariO:0017<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0014\" target=\"_blank\" >VariO:0014<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0018\" target=\"_blank\" >VariO:0018<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0040\" target=\"_blank\" >VariO:0040<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0043\" target=\"_blank\" >VariO:0043<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0124\" target=\"_blank\" >VariO:0124<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0161\" target=\"_blank\" >VariO:0161<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0362\" target=\"_blank\" >VariO:0362<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0444\" target=\"_blank\" >VariO:0444<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0446\" target=\"_blank\" >VariO:0446<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0450\" target=\"_blank\" >VariO:0450<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0508\" target=\"_blank\" >VariO:0508<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0509\" target=\"_blank\" >VariO:0509<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0474\" target=\"_blank\" >VariO:0474<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0125\" target=\"_blank\" >VariO:0125<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0135\" target=\"_blank\" >VariO:0135<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0141\" target=\"_blank\" >VariO:0141<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0143\" target=\"_blank\" >VariO:0143<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0142\" target=\"_blank\" >VariO:0142<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0145\" target=\"_blank\" >VariO:0145<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0136\" target=\"_blank\" >VariO:0136<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0144\" target=\"_blank\" >VariO:0144<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0126\" target=\"_blank\" >VariO:0126<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0334\" target=\"_blank\" >VariO:0334<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0497\" target=\"_blank\" >VariO:0497<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0022\" target=\"_blank\" >VariO:0022<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0021\" target=\"_blank\" >VariO:0021<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0153\" target=\"_blank\" >VariO:0153<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0193\" target=\"_blank\" >VariO:0193<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0132\" target=\"_blank\" >VariO:0132<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0187\" target=\"_blank\" >VariO:0187<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0296\" target=\"_blank\" >VariO:0296<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0294\" target=\"_blank\" >VariO:0294<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0151\" target=\"_blank\" >VariO:0151<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0154\" target=\"_blank\" >VariO:0154<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0171\" target=\"_blank\" >VariO:0171<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0175\" target=\"_blank\" >VariO:0175<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0382\" target=\"_blank\" >VariO:0382<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0137\" target=\"_blank\" >VariO:0137<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0401\" target=\"_blank\" >VariO:0401<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0008\" target=\"_blank\" >VariO:0008<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0056\" target=\"_blank\" >VariO:0056<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0064\" target=\"_blank\" >VariO:0064<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0052\" target=\"_blank\" >VariO:0052<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0053\" target=\"_blank\" >VariO:0053<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0054\" target=\"_blank\" >VariO:0054<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0038\" target=\"_blank\" >VariO:0038<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0119\" target=\"_blank\" >VariO:0119<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0120\" target=\"_blank\" >VariO:0120<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0051\" target=\"_blank\" >VariO:0051<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0080\" target=\"_blank\" >VariO:0080<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0036\" target=\"_blank\" >VariO:0036<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0058\" target=\"_blank\" >VariO:0058<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0118\" target=\"_blank\" >VariO:0118<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0109\" target=\"_blank\" >VariO:0109<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0121\" target=\"_blank\" >VariO:0121<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0055\" target=\"_blank\" >VariO:0055<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0110\" target=\"_blank\" >VariO:0110<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0034\" target=\"_blank\" >VariO:0034<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0033\" target=\"_blank\" >VariO:0033<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0070\" target=\"_blank\" >VariO:0070<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0152\" target=\"_blank\" >VariO:0152<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0400\" target=\"_blank\" >VariO:0400<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0006\" target=\"_blank\" >VariO:0006<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0104\" target=\"_blank\" >VariO:0104<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0073\" target=\"_blank\" >VariO:0073<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0157\" target=\"_blank\" >VariO:0157<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0156\" target=\"_blank\" >VariO:0156<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0502\" target=\"_blank\" >VariO:0502<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0131\" target=\"_blank\" >VariO:0131<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0030\" target=\"_blank\" >VariO:0030<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0494\" target=\"_blank\" >VariO:0494<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0478\" target=\"_blank\" >VariO:0478<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0190\" target=\"_blank\" >VariO:0190<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0350\" target=\"_blank\" >VariO:0350<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0295\" target=\"_blank\" >VariO:0295<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0158\" target=\"_blank\" >VariO:0158<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0031\" target=\"_blank\" >VariO:0031<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0039\" target=\"_blank\" >VariO:0039<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0493\" target=\"_blank\" >VariO:0493<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0492\" target=\"_blank\" >VariO:0492<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0485\" target=\"_blank\" >VariO:0485<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0191\" target=\"_blank\" >VariO:0191<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0468\" target=\"_blank\" >VariO:0468<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0189\" target=\"_blank\" >VariO:0189<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0138\" target=\"_blank\" >VariO:0138<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0128\" target=\"_blank\" >VariO:0128<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0155\" target=\"_blank\" >VariO:0155<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0297\" target=\"_blank\" >VariO:0297<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0002\" target=\"_blank\" >VariO:0002<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0003\" target=\"_blank\" >VariO:0003<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0060\" target=\"_blank\" >VariO:0060<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0162\" target=\"_blank\" >VariO:0162<\/a>","<a href=\"https://www.ebi.ac.uk/ols/ontologies/vario/terms?iri=http://purl.obolibrary.org/obo/VariO_0495\" target=\"_blank\" >VariO:0495<\/a>"],["variation","protein truncation","nonsynonymous variation","amino acid deletion","amino acid insertion","protein gain of function","protein loss of function","protein elongation","variation in intron","effect on RNA splicing","de novo variation","somatic variation","mitochondrial DNA affected","affected splice site","effect on mode of splicing","intron retention","C-terminal protein elongation","DNA chain variation","DNA deletion","DNA indel","DNA insertion","DNA inversion","DNA substitution","DNA translocation","N-terminal protein elongation","RNA splicing change","alternatively terminated mRNA","amino acid indel","amino acid substitution","chromatin variation","chromosomal deletion","chromosomal variation","copy number variation","disease associated","disease causing","effect on DNA repair","effect on DNA replication","effect on DNA tertiary structure","effect on DNA triple helix","effect on RNA secondary structure","effect on RNA tertiary structure","effect on amino acid transfer of RNA","effect on catalytic protein function","effect on enzyme reaction kinetics","effect on protein 3D structure","effect on protein abundance","effect on protein activity","effect on protein affinity","effect on protein aggregation","effect on protein binding site","effect on protein catalytic site","effect on protein degradation","effect on protein helix","effect on protein inclusion body formation","effect on protein interaction","effect on protein interaction site","effect on protein processing","effect on protein quaternary structure","effect on protein specificity","effect on protein splicing","effect on protein stability","effect on protein subcellular localization","effect on protein tertiary structure","effect on regulatory function of DNA","effect on regulatory function of RNA","effect on structural protein","effect on transmembrane polypeptide","effect to protein fold","epigenetic DNA methylation","epigenetic DNA modification","exon skipping","genomic variation","in-frame indel","long non-coding RNA","microRNA","mononucleotide expansion","non-protein coding RNA","not related to clinical phenotype","nucleosome positioning","out-of-frame indel","protein function change","ribosomal RNA","short non-coding RNA","spliceosomal RNA","tetranucleotide expansion","transfer RNA","trinucleotide expansion","variant","variation affecting DNA","variation affecting DNA structure","variation affecting RNA","variation affecting protein","variation affecting protein function","variation affecting protein structure","variation in exon","very long non-coding RNA"],["Alteration in DNA, RNA or protein.","Shortening of protein sequence from terminus.","mRNA variation leading to amino acid change in translated protein. The variant alters the codon so that it encodes another amino acid.","Removal of one or more continuous amino acids from protein.","Addition of one or more amino acids to protein sequence.","Effect of variation causing new or enhanced protein activity.","Effect of variation reducing or abolishing protein activity.","Variation prolonging protein chain at an end.","Variation located in intron.","Effect to process where introns in mRNA are cut away from exons.","Variation that has emerged in a germ cell on one of the parents or in the fertilized egg during early embryogenesis.","Variation that has its origin in a cell in soma.","Variation affecting DNA within mitochondria.","Type of variation affecting splice site.","Variation affecting the type of RNA splicing.","Inclusion intron sequence to mRNA.","Addition of one or more amino acids to protein C-terminus.","Variation at DNA chain.","Removal of one or more continuous nucleotides from DNA sequence.","A complex DNA variation consisting of both nucleotide insertion(s) and deletion(s).","Addition of one or more nucleotides between two adjacent nucleotides in the DNA sequence.","A continuous stretch of DNA sequence inserted to the same position in reverse orientation.","Substitution of a DNA nucleotide.","A continuous stretch of DNA sequence moved to a new position within a chromosome.","Addition of one or more amino acids to protein N-terminus.","Change to RNA splicing.","Variation causing alternative mRNA termination.","A complex protein variation consisting of both amino acid insertion(s) and deletion(s).","Substitution of an amino acid in protein.","Variation affecting chromatin.","Deletion of chromosomal region.","Variation at chromosomal level.","Increase or decrease of the number of copies of a chromosomal region. Sizes of copy number variations range from about 1 kilobase to several megabases.","Variation is disease related.","Variation is causative of disease.","Variation affecting the process of restoring DNA after damage.","Variation originating from semi conservative DNA strand synthesis. The template for replication is either DNA or RNA molecule.","Variation affecting DNA tertiary structure.","Variation affecting DNA helix formed of three strands.","Variation affecting RNA secondary structure.","Variation affecting RNA tertiary structure.","Variation affecting RNA function in amino acid transfer.","Effect of variation on catalytic function of protein.","Effect of variation to enzyme reaction kinetics.","Variation affecting protein three dimensional structure.","Variation affecting abundance of produced protein molecules.","Effect of variation on activity of protein.","Effect of variation on protein affinity to binding molecule(s).","Variation affecting protein aggregation tendency.","Variation affecting region on the surface of a protein that interacts with another molecule.","Variation affecting amino acid(s) in protein catalytic site.","Effect of variation on degradation of protein.","Variation affecting secondary structure conformation where the peptide backbone forms a coil.","Variation affecting the formation of particles of aggregated proteins.","Effect of variation on the interaction of protein with its partner.","Variation affecting ligand binding amino acid(s) in protein.","Variation affecting site of protein maturation by cleavage of peptide bond(s).","Variation affecting three dimensional structure of a protein complex.","Effect of variation on substrate binding specificity of protein.","Variation affecting post-translational removal of peptide sequences from within a protein sequence.","Effect of variation on stability of protein.","Effect of variation on the targeting of a protein within a cell or cellular compartment.","Variation affecting protein three dimensional structure.","Variation affecting regulatory function of DNA.","Variation affecting regulatory function of RNA.","Effect of variation on structural role of protein. Structural proteins are fibrous and involved in increasing rigidity and stiffness of biological systems.","Variation altering membrane spanning protein.","Variation affecting protein tertiary structure.","Inheritable cytosine or adenosine pyrimidine ring methylation regulating gene expression.","Hereditary variation of DNA not affecting primary sequence.","Variation where an exon is completele cleaved out from a mature transcript.","Variation of genomic level.","RNA indel not affecting reading frame after indel position.","Non-coding RNA longer than 200 nucleotides or base pairs.","Short non-coding RNA that binds to complementary region in mRNA and silences and regulates gene expression.","Tandem repetitive sequence consisting of one nucleotide type.","Variation affecting RNA not coding for protein.","Variation is not related to clinical phenotype.","Positioning of nucleosomes to DNA strand.","RNA indel containing a number of nucleotides not divisible by three and therefore causing change to reading frame.","Type of protein function affecting variation.","Non-coding RNA constituent of ribosome.","Non-coding RNA shorter than 200 nucleotides or base pairs.",null,"Tandem repetitive sequence consisting of four nucleotide units.","Transfer RNA involved in protein synthesis. Modiefied tRNA contains amino acid and carries it to ribosome.","Tandem repetitive sequence consisting of three nucleotide units.","A genetic character, organism or individual with a difference to reference state.","Effects of a variation on DNA level.","Variation affecting structure of DNA.","Effects of a variation on RNA level.","Effects of a variation on protein level.","Effect of variation on protein function.","Variation affecting structure of protein.","Variation located in exon.","Non-coding RNA longer than 10 kb."],[1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1],[1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null,null]],"container":"<table class=\"display\">\n  <thead>\n    <tr>\n      <th> <\/th>\n      <th>vario_id<\/th>\n      <th>vario_name<\/th>\n      <th>definition<\/th>\n      <th>use<\/th>\n      <th>sort<\/th>\n    <\/tr>\n  <\/thead>\n<\/table>","options":{"columnDefs":[{"className":"dt-right","targets":[4,5]},{"orderable":false,"targets":0},{"name":" ","targets":0},{"name":"vario_id","targets":1},{"name":"vario_name","targets":2},{"name":"definition","targets":3},{"name":"use","targets":4},{"name":"sort","targets":5}],"order":[],"autoWidth":false,"orderClasses":false,"orderCellsTop":true}},"evals":[],"jsHooks":[]}</script>
 </div>
 <div id="mode-of-inheritance-ontology" class="section level2 hasAnchor" number="4.4">
 <h2><span class="header-section-number">4.4</span> Mode of Inheritance ontology<a href="database-structure.html#mode-of-inheritance-ontology" class="anchor-section" aria-label="Anchor link to header"></a></h2>
 <p>We use the “Human Phenotype Ontology” as ontology for the mode of inheritance.
 Currently active terms are represented in following table.</p>
-<div class="datatables html-widget html-fill-item" id="htmlwidget-ef9acd5589aaf69aa9f5" style="width:100%;height:auto;"></div>
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