From 977b70feef6070ad074d65964e94a7b3ea0ae4ec Mon Sep 17 00:00:00 2001 From: Sebastian Lobentanzer Date: Tue, 16 Jan 2024 00:15:57 +0100 Subject: [PATCH] phrasing and reference --- content/10.introduction.md | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/content/10.introduction.md b/content/10.introduction.md index e860cd0..1b56c63 100644 --- a/content/10.introduction.md +++ b/content/10.introduction.md @@ -7,7 +7,7 @@ In addition, biological events are context-dependent, for instance with respect Large Language Models (LLMs) of the current generation, on the other hand, can access enormous amounts of knowledge, encoded (incomprehensibly) in their billions of parameters [@doi:10.48550/arxiv.2204.02311;@doi:10.48550/arxiv.2201.08239;@doi:10.48550/arxiv.2303.08774]. Trained correctly, they can recall and combine virtually limitless knowledge from their training set. -ChatGPT has taken the world by storm, and many biomedical researchers already use LLMs in their daily work, for general as well as bioinformatics-specific tasks [@doi:10.1101/2023.04.16.537094;@doi:10.1038/s41587-023-01789-6]. +ChatGPT has taken the world by storm, and many biomedical researchers already use LLMs in their daily work, for general as well as research tasks [@doi:10.1038/s41586-023-06792-0;@doi:10.1101/2023.04.16.537094;@doi:10.1038/s41587-023-01789-6]. However, the current, predominantly manual, way of interacting with LLMs is virtually non-reproducible, and their behaviour can be erratic. For instance, they are known to confabulate: they make up facts as they go along, and, to make matters worse, are convinced - and convincing - regarding the truth of their confabulations [@doi:10.1038/s41586-023-05881-4;@doi:10.1038/s41587-023-01789-6]. While current efforts towards Artificial General Intelligence manage to ameliorate some of the shortcomings by ensembling multiple models [@{https://python.langchain.com}] with long-term memory stores [@{https://autogpt.net/}], the current generation of AI does not inspire adequate trust to be applied to biomedical problems without supervision [@doi:10.1038/s41586-023-05881-4].