diff --git a/recipes/stduuid/all/conandata.yml b/recipes/stduuid/all/conandata.yml
index cb02ec2f29148..106008491388a 100644
--- a/recipes/stduuid/all/conandata.yml
+++ b/recipes/stduuid/all/conandata.yml
@@ -8,3 +8,12 @@ sources:
   "1.0":
     url: "https://github.com/mariusbancila/stduuid/archive/v1.0.tar.gz"
     sha256: "e96f2ac7c950c3c24d7e2e44a84236277b7774ee346dcc620edf400d9eda0a3c"
+patches:
+  "1.2.2":
+    - patch_file: "patches/1.2.2-handle-span-header.patch"
+      patch_description: "Conditionally include span header based on compiler definition"
+      patch_type: "conan"
+  "1.2.3":
+    - patch_file: "patches/1.2.3-handle-span-header.patch"
+      patch_description: "Conditionally include span header based on compiler definition"
+      patch_type: "conan"
diff --git a/recipes/stduuid/all/conanfile.py b/recipes/stduuid/all/conanfile.py
index 0ca3e6b2dcb08..740dfa380f1ad 100644
--- a/recipes/stduuid/all/conanfile.py
+++ b/recipes/stduuid/all/conanfile.py
@@ -1,7 +1,7 @@
 from conan import ConanFile
 from conan.errors import ConanInvalidConfiguration
-from conan.tools.build import check_min_cppstd
-from conan.tools.files import copy, get
+from conan.tools.build import check_min_cppstd, valid_min_cppstd
+from conan.tools.files import apply_conandata_patches, copy, export_conandata_patches, get
 from conan.tools.layout import basic_layout
 from conan.tools.scm import Version
 import os
@@ -18,16 +18,14 @@ class StduuidConan(ConanFile):
     homepage = "https://github.com/mariusbancila/stduuid"
     settings = "os", "arch", "compiler", "build_type"
     options = {
+        # True: Use std::span
+        # False: Use gsl::span
         "with_cxx20_span": [True, False],
     }
-    default_options = {
-        "with_cxx20_span": False,
-    }
-    no_copy_source = True
 
     @property
     def _min_cppstd(self):
-        return "20" if self.options.with_cxx20_span else "17"
+        return "20" if self.options.get_safe("with_cxx20_span") else "17"
 
     @property
     def _compilers_minimum_version(self):
@@ -38,13 +36,26 @@ def _compilers_minimum_version(self):
             "msvc": "191",
             "Visual Studio": "15",
         }
+    
+    def export_sources(self):
+        export_conandata_patches(self)
 
     def layout(self):
         basic_layout(self, src_folder="src")
 
+    def config_options(self):
+        if Version(self.version) == "1.0":
+            # Version 1.0 unconditionally depends on gsl span
+            del self.options.with_cxx20_span
+        else:
+            # Conditionally set the default value of with_cxx20_span
+            # if cppstd is set and is 20 or greater
+            self.options.with_cxx20_span = (self.settings.compiler.get_safe("cppstd", False)
+                                            and valid_min_cppstd(self, 20))
+
     def requirements(self):
-        if not self.options.with_cxx20_span:
-            self.requires("ms-gsl/3.1.0", transitive_headers=True)
+        if not self.options.get_safe("with_cxx20_span") or Version(self.version) == "1.0":
+            self.requires("ms-gsl/4.0.0", transitive_headers=True)
         if self.settings.os == "Linux" and Version(self.version) <= "1.0":
             self.requires("util-linux-libuuid/2.39", transitive_headers=True, transitive_libs=True)
 
@@ -52,7 +63,7 @@ def package_id(self):
         self.info.clear()
 
     def validate(self):
-        if self.settings.compiler.get_safe("cppsd"):
+        if self.settings.compiler.get_safe("cppstd"):
             check_min_cppstd(self, self._min_cppstd)
 
         minimum_version = self._compilers_minimum_version.get(str(self.settings.compiler), False)
@@ -62,8 +73,8 @@ def validate(self):
             )
 
     def source(self):
-        get(self, **self.conan_data["sources"][self.version],
-            destination=self.source_folder, strip_root=True)
+        get(self, **self.conan_data["sources"][self.version], strip_root=True)
+        apply_conandata_patches(self)
 
     def build(self):
         pass
@@ -75,5 +86,5 @@ def package(self):
     def package_info(self):
         self.cpp_info.bindirs = []
         self.cpp_info.libdirs = []
-        if not self.options.with_cxx20_span:
-            self.cpp_info.includedirs.append(os.path.join(self.dependencies["ms-gsl"].cpp_info.includedirs[0], "gsl"))
+        if self.options.get_safe("with_cxx20_span"):
+            self.cpp_info.defines = ["LIBUUID_CPP20_OR_GREATER"]
diff --git a/recipes/stduuid/all/patches/1.2.2-handle-span-header.patch b/recipes/stduuid/all/patches/1.2.2-handle-span-header.patch
new file mode 100644
index 0000000000000..840c78174c772
--- /dev/null
+++ b/recipes/stduuid/all/patches/1.2.2-handle-span-header.patch
@@ -0,0 +1,26 @@
+diff --git a/include/uuid.h b/include/uuid.h
+index 600846f..5f00a49 100644
+--- a/include/uuid.h
++++ b/include/uuid.h
+@@ -15,7 +15,11 @@
+ #include <chrono>
+ #include <numeric>
+ #include <atomic>
+-#include <span>
++#if defined(LIBUUID_CPP20_OR_GREATER)
++# include <span>
++#else
++# include <gsl/span>
++#endif
+ 
+ #ifdef _WIN32
+ 
+@@ -51,7 +55,7 @@
+ 
+ namespace uuids
+ {
+-#ifdef __cpp_lib_span
++#if defined(LIBUUID_CPP20_OR_GREATER)
+    template <class ElementType, std::size_t Extent>
+    using span = std::span<ElementType, Extent>;
+ #else
diff --git a/recipes/stduuid/all/patches/1.2.3-handle-span-header.patch b/recipes/stduuid/all/patches/1.2.3-handle-span-header.patch
new file mode 100644
index 0000000000000..fae5f65b66c25
--- /dev/null
+++ b/recipes/stduuid/all/patches/1.2.3-handle-span-header.patch
@@ -0,0 +1,29 @@
+diff --git a/include/uuid.h b/include/uuid.h
+index d48059d..4d14e4d 100644
+--- a/include/uuid.h
++++ b/include/uuid.h
+@@ -17,15 +17,6 @@
+ #include <numeric>
+ #include <atomic>
+ 
+-#ifdef __cplusplus
+-
+-#  if (__cplusplus >= 202002L) || (defined(_MSVC_LANG) && _MSVC_LANG >= 202002L)
+-#    define LIBUUID_CPP20_OR_GREATER
+-#  endif
+-
+-#endif
+-
+-
+ #ifdef LIBUUID_CPP20_OR_GREATER
+ #include <span>
+ #else
+@@ -66,7 +57,7 @@
+ 
+ namespace uuids
+ {
+-#ifdef __cpp_lib_span
++#if defined(LIBUUID_CPP20_OR_GREATER)
+    template <class ElementType, std::size_t Extent>
+    using span = std::span<ElementType, Extent>;
+ #else