DESCRIPTION

Package: GAMclust
Title: GAM-clustering: Metabolic Modules Derivig From RNAseq Data
Version: 0.0.0.9000
Authors@R: 
    person(given = "Anastasiia",
           family = "Gainullina",
           role = c("aut", "cre"),
           email = "anastasiia.gainullina@gmail.com",
           comment = c(ORCID = "0000-0003-3796-2337"))
    person(given = "Evgeniia",
           family = "Chikina",
           role = "ctb")
    person(given = "Alexey",
           family = "Sergushichev",
           role = "aut",
           email = "alsergbox@gmail.com",
           comment = c(ORCID = "0000-0003-1159-7220"))
Author: Anastasiia Gainullina [aut, cre],
        Alexey Sergushichev [aut],
Maintainer: Anastasiia Gainullina <anastasiia.gainullina@gmail.com>
Description: The GAM-clustering method reveals metabolic variability within dataset using a novel 
    network-based computational approach. This method utilizes cellular transcriptional profiles as 
    proxies. The metabolic network of reactions is presented as a graph. This graph has vertices 
    corresponding to metabolites and the edges corresponding to the reactions with the expressed genes. 
    In the graph the method tries to find a set of connected subgraphs. Genes of each connected subgraph 
    have highly correlated expression pattern.
biocViews: GeneExpression, Pathways, Network
Depends: 
    R (>= 3.5),
    data.table
Imports:
    Biobase,
    cluster,
    cowplot,
    data.table,
    dplyr,
    fgsea,
    gatom,
    ggplot2,
    igraph,
    limma,
    mwcsr,
    irlba,
    pheatmap
Suggests:
    AnnotationDbi,
    org.Mm.eg.db,
    reactome.db,
    KEGGREST,
    Seurat,
    Rgraphviz,
    rsvg,
    testthat,
    knitr
License: MIT + file LICENSE
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.2.3
VignetteBuilder: knitr
URL: https://github.com/ctlab/GAMclust
BugReports: https://github.com/ctlab/GAMclust/issues