diff --git a/x-pack/packages/security/ui_components/src/kibana_privilege_table/feature_table_expanded_row.tsx b/x-pack/packages/security/ui_components/src/kibana_privilege_table/feature_table_expanded_row.tsx
index 436119884f51d..ad14f76187236 100644
--- a/x-pack/packages/security/ui_components/src/kibana_privilege_table/feature_table_expanded_row.tsx
+++ b/x-pack/packages/security/ui_components/src/kibana_privilege_table/feature_table_expanded_row.tsx
@@ -132,6 +132,7 @@ export const FeatureTableExpandedRow = ({
               onChange={(updatedPrivileges) => onChange(feature.id, updatedPrivileges)}
               selectedFeaturePrivileges={selectedFeaturePrivileges}
               disabled={disabled || !isCustomizing || isDisabledDueToSpaceSelection}
+              allSpacesSelected={allSpacesSelected}
             />
           </EuiFlexItem>
         );
diff --git a/x-pack/packages/security/ui_components/src/kibana_privilege_table/sub_feature_form.tsx b/x-pack/packages/security/ui_components/src/kibana_privilege_table/sub_feature_form.tsx
index 21bf95955328b..f2def06147a7a 100644
--- a/x-pack/packages/security/ui_components/src/kibana_privilege_table/sub_feature_form.tsx
+++ b/x-pack/packages/security/ui_components/src/kibana_privilege_table/sub_feature_form.tsx
@@ -34,6 +34,7 @@ interface Props {
   onChange: (selectedPrivileges: string[]) => void;
   disabled?: boolean;
   categoryId?: string;
+  allSpacesSelected?: boolean;
 }
 
 export const SubFeatureForm = (props: Props) => {
@@ -157,12 +158,18 @@ export const SubFeatureForm = (props: Props) => {
     privilegeGroup: SubFeaturePrivilegeGroup,
     index: number
   ) {
+    const nonePrivilege = {
+      id: NO_PRIVILEGE_VALUE,
+      label: 'None',
+      isDisabled: props.disabled,
+    };
+
     const firstSelectedPrivilege =
       props.privilegeCalculator.getSelectedMutuallyExclusiveSubFeaturePrivilege(
         props.featureId,
         privilegeGroup,
         props.privilegeIndex
-      );
+      ) ?? nonePrivilege;
 
     const options = [
       ...privilegeGroup.privileges.map((privilege, privilegeIndex) => {
@@ -174,11 +181,12 @@ export const SubFeatureForm = (props: Props) => {
       }),
     ];
 
-    options.push({
-      id: NO_PRIVILEGE_VALUE,
-      label: 'None',
-      isDisabled: props.disabled,
-    });
+    options.push(nonePrivilege);
+
+    const idSelected =
+      props.subFeature.requireAllSpaces && !props.allSpacesSelected
+        ? nonePrivilege.id
+        : firstSelectedPrivilege.id;
 
     return (
       <EuiButtonGroup
@@ -187,7 +195,7 @@ export const SubFeatureForm = (props: Props) => {
         data-test-subj="mutexSubFeaturePrivilegeControl"
         isFullWidth
         options={options}
-        idSelected={firstSelectedPrivilege?.id ?? NO_PRIVILEGE_VALUE}
+        idSelected={idSelected}
         isDisabled={props.disabled}
         onChange={(selectedPrivilegeId: string) => {
           // Deselect all privileges which belong to this mutually-exclusive group
diff --git a/x-pack/plugins/security/public/management/roles/edit_role/privileges/kibana/privilege_summary/privilege_summary_expanded_row.tsx b/x-pack/plugins/security/public/management/roles/edit_role/privileges/kibana/privilege_summary/privilege_summary_expanded_row.tsx
index 83f1e26ad1284..46d6fc34fe497 100644
--- a/x-pack/plugins/security/public/management/roles/edit_role/privileges/kibana/privilege_summary/privilege_summary_expanded_row.tsx
+++ b/x-pack/plugins/security/public/management/roles/edit_role/privileges/kibana/privilege_summary/privilege_summary_expanded_row.tsx
@@ -20,6 +20,7 @@ import type { EffectiveFeaturePrivileges } from './privilege_summary_calculator'
 interface Props {
   feature: SecuredFeature;
   effectiveFeaturePrivileges: Array<EffectiveFeaturePrivileges['featureId']>;
+  isAllSpacesSelected: boolean;
 }
 
 export const PrivilegeSummaryExpandedRow = (props: Props) => {
@@ -37,7 +38,9 @@ export const PrivilegeSummaryExpandedRow = (props: Props) => {
               {props.effectiveFeaturePrivileges.map((privs, index) => {
                 return (
                   <EuiFlexItem key={index} data-test-subj={`entry-${index}`}>
-                    {subFeature.getPrivilegeGroups().map(renderPrivilegeGroup(privs.subFeature))}
+                    {subFeature
+                      .getPrivilegeGroups()
+                      .map(renderPrivilegeGroup(privs.subFeature, subFeature.requireAllSpaces))}
                   </EuiFlexItem>
                 );
               })}
@@ -48,7 +51,10 @@ export const PrivilegeSummaryExpandedRow = (props: Props) => {
     </EuiFlexGroup>
   );
 
-  function renderPrivilegeGroup(effectiveSubFeaturePrivileges: string[]) {
+  function renderPrivilegeGroup(
+    effectiveSubFeaturePrivileges: string[],
+    requireAllSpaces: boolean
+  ) {
     return (privilegeGroup: SubFeaturePrivilegeGroup, index: number) => {
       switch (privilegeGroup.groupType) {
         case 'independent':
@@ -61,7 +67,8 @@ export const PrivilegeSummaryExpandedRow = (props: Props) => {
           return renderMutuallyExclusivePrivilegeGroup(
             effectiveSubFeaturePrivileges,
             privilegeGroup,
-            index
+            index,
+            requireAllSpaces
           );
         default:
           throw new Error(`Unsupported privilege group type: ${privilegeGroup.groupType}`);
@@ -112,11 +119,14 @@ export const PrivilegeSummaryExpandedRow = (props: Props) => {
   function renderMutuallyExclusivePrivilegeGroup(
     effectiveSubFeaturePrivileges: string[],
     privilegeGroup: SubFeaturePrivilegeGroup,
-    index: number
+    index: number,
+    requireAllSpaces: boolean
   ) {
-    const firstSelectedPrivilege = privilegeGroup.privileges.find((p) =>
-      effectiveSubFeaturePrivileges.includes(p.id)
-    )?.name;
+    const isDisabledDueToSpaceSelection = requireAllSpaces && !props.isAllSpacesSelected;
+
+    const firstSelectedPrivilege = !isDisabledDueToSpaceSelection
+      ? privilegeGroup.privileges.find((p) => effectiveSubFeaturePrivileges.includes(p.id))?.name
+      : null;
 
     return (
       <EuiFlexGroup gutterSize="s" key={index} data-test-subj="mutexPrivilege">
diff --git a/x-pack/plugins/security/public/management/roles/edit_role/privileges/kibana/privilege_summary/privilege_summary_table.tsx b/x-pack/plugins/security/public/management/roles/edit_role/privileges/kibana/privilege_summary/privilege_summary_table.tsx
index 5dc856e5af5d9..82167ed9f1a2d 100644
--- a/x-pack/plugins/security/public/management/roles/edit_role/privileges/kibana/privilege_summary/privilege_summary_table.tsx
+++ b/x-pack/plugins/security/public/management/roles/edit_role/privileges/kibana/privilege_summary/privilege_summary_table.tsx
@@ -52,7 +52,7 @@ function showPrivilege(allSpacesSelected: boolean, primaryFeature?: PrimaryFeatu
   if (
     primaryFeature?.name == null ||
     primaryFeature?.disabled ||
-    (primaryFeature.requireAllSpaces && !allSpacesSelected)
+    (primaryFeature?.requireAllSpaces && !allSpacesSelected)
   ) {
     return 'None';
   }
@@ -218,6 +218,8 @@ export const PrivilegeSummaryTable = (props: PrivilegeSummaryTableProps) => {
       };
     });
 
+    const isAllSpacesSelected = props.spaces.some((space) => space.id === ALL_SPACES_ID);
+
     accordions.push(
       <EuiAccordion
         id={`privilegeSummaryFeatureCategory_${category.id}`}
@@ -242,6 +244,7 @@ export const PrivilegeSummaryTable = (props: PrivilegeSummaryTableProps) => {
                 <PrivilegeSummaryExpandedRow
                   feature={props.kibanaPrivileges.getSecuredFeature(featureId)}
                   effectiveFeaturePrivileges={Object.values(privileges).map((p) => p[featureId])}
+                  isAllSpacesSelected={isAllSpacesSelected}
                 />
               ),
             };
diff --git a/x-pack/plugins/security/public/management/roles/edit_role/privileges/kibana/space_aware_privilege_section/space_aware_privilege_section.tsx b/x-pack/plugins/security/public/management/roles/edit_role/privileges/kibana/space_aware_privilege_section/space_aware_privilege_section.tsx
index 2bb3292932870..2773dd92753ce 100644
--- a/x-pack/plugins/security/public/management/roles/edit_role/privileges/kibana/space_aware_privilege_section/space_aware_privilege_section.tsx
+++ b/x-pack/plugins/security/public/management/roles/edit_role/privileges/kibana/space_aware_privilege_section/space_aware_privilege_section.tsx
@@ -218,7 +218,7 @@ export class SpaceAwarePrivilegeSection extends Component<Props, State> {
     const viewMatrixButton = (
       <PrivilegeSummary
         role={this.props.role}
-        spaces={this.getDisplaySpaces()}
+        spaces={this.getSelectedSpaces()}
         kibanaPrivileges={this.props.kibanaPrivileges}
         canCustomizeSubFeaturePrivileges={this.props.canCustomizeSubFeaturePrivileges}
         spacesApiUi={this.props.spacesApiUi}
@@ -240,6 +240,11 @@ export class SpaceAwarePrivilegeSection extends Component<Props, State> {
     return [this.globalSpaceEntry, ...this.props.spaces];
   };
 
+  private getSelectedSpaces = () =>
+    this.getDisplaySpaces().filter((space) =>
+      this.props.role.kibana.some((entry) => entry.spaces.includes(space.id))
+    );
+
   private getAvailableSpaces = (includeSpacesFromPrivilegeIndex: number = -1) => {
     const spacesToExclude = _.uniq(
       _.flatten(