diff --git a/derive/src/lib.rs b/derive/src/lib.rs
index 5017d10..e1b8db2 100644
--- a/derive/src/lib.rs
+++ b/derive/src/lib.rs
@@ -330,6 +330,7 @@ pub fn host_fn(
 
                     #vis unsafe fn #name #generics (#original_inputs) -> Result<#output, extism_pdk::Error> {
                         let res = extism_pdk::Memory::from(#impl_name(#(#into_inputs),*));
+                        extism_pdk::get_host_func_error()?;
                         <#output as extism_pdk::FromBytes>::from_bytes(&res.to_vec())
                     }
                 };
@@ -341,6 +342,7 @@ pub fn host_fn(
 
                     #vis unsafe fn #name #generics (#original_inputs) -> Result<#output, extism_pdk::Error> {
                         let res = #impl_name(#(#into_inputs),*);
+                        extism_pdk::get_host_func_error()?;
                         Ok(res)
                     }
                 };
diff --git a/src/error.rs b/src/error.rs
new file mode 100644
index 0000000..04b84af
--- /dev/null
+++ b/src/error.rs
@@ -0,0 +1,62 @@
+use crate::*;
+use base64::prelude::*;
+use std::sync::LazyLock;
+
+
+/// If the host is appending a sentinel prefix to the host function errors
+/// it will also pass that prefix to the guest, so the guest knows what to
+/// trim off the front of the raw bytes. This is stored in a lazy lock because
+/// it is sent once and never changed. Subsequent calls to get host function
+/// errors will not need to recompute this value.
+static HOST_FUNC_ERROR_PREFIX: LazyLock<Option<Vec<u8>>> = LazyLock::new(|| {
+    std::env::var("EXTISM_HOST_FUNC_ERROR_PREFIX")
+        .ok()
+        .and_then(|p| BASE64_STANDARD.decode(p.as_bytes()).ok())
+});
+
+/// Checks to see if the most recent host function call returned an error.
+/// Retrieves any error set by the host function and stripes any sentinel bytes from it.
+///
+/// This function interacts with the Extism kernel's `error_get` mechanism to fetch any
+/// error currently stored in WASM memory. If an error exists, it determines whether the
+/// error was created by a host function (using sentinel bytes in the prefix).
+///
+/// ### Behavior:
+/// - Calls `extism::error_get` to retrieve the current error's memory offset.
+/// - If no error is present (offset is `0`), returns `Ok(())`.
+/// - Attempts to locate the memory at the given offset and process the error bytes:
+///   - If a known sentinel prefix is found, the function strips the prefix and treats
+///     the remaining bytes as the error message from the host function.
+///   - If no prefix is present, the error is returned as-is.
+/// - Converts the error bytes into a UTF-8 string and wraps it in an `Error::msg`.
+///
+/// ### Notes:
+/// - Errors originating from host functions are marked with a unique sentinel prefix
+///   (defined by `HOST_FUNC_ERROR_PREFIX`). This prefix is appended during serialization
+///   by the host and removed during deserialization here, enabling reliable error
+///   identification and processing.
+pub fn get_host_func_error() -> Result<(), Error> {
+    let offset = unsafe { extism::error_get() };
+    if offset == 0 {
+        return Ok(());
+    }
+
+    // We need to reset the error now that we've read it
+    unsafe { extism::error_set(0) };
+
+    if let Some(mem) = Memory::find(offset).map(|mem| mem.to_vec()) {
+        let message = if let Some(prefix) = HOST_FUNC_ERROR_PREFIX.as_ref() {
+            // Attempt to strip the sentinel prefix for host function errors
+            mem.strip_prefix(prefix.as_slice())
+                .map(|stripped| String::from_utf8_lossy(stripped))
+                .unwrap_or_else(|| String::from_utf8_lossy(&mem))
+        } else {
+            // Handle the memory as a UTF-8 string if no prefix is available
+            String::from_utf8_lossy(&mem)
+        };
+
+        return Err(Error::msg(message.to_string()));
+    }
+
+    Ok(())
+}
\ No newline at end of file
diff --git a/src/extism.rs b/src/extism.rs
index bf7674c..7a835e0 100644
--- a/src/extism.rs
+++ b/src/extism.rs
@@ -9,6 +9,7 @@ extern "C" {
     pub fn free(offs: u64);
     pub fn output_set(offs: u64, length: u64);
     pub fn error_set(offs: u64);
+    pub fn error_get() -> u64;
     pub fn store_u8(offs: u64, data: u8);
     pub fn load_u8(offs: u64) -> u8;
     pub fn store_u64(offs: u64, data: u64);
diff --git a/src/lib.rs b/src/lib.rs
index 2cd9cee..a464789 100644
--- a/src/lib.rs
+++ b/src/lib.rs
@@ -19,6 +19,10 @@ pub mod var;
 /// Types and functions for making HTTP requests
 pub mod http;
 
+/// Functions and utilities for working with host function errors
+mod error;
+pub use error::get_host_func_error;
+
 pub use anyhow::Error;
 pub use extism_convert::*;
 pub use extism_convert::{FromBytes, FromBytesOwned, ToBytes};