From 39ac60ee57fc97120f8fa4e32b136e0819d5866e Mon Sep 17 00:00:00 2001
From: Max <63072723+X-E-M-E-X@users.noreply.github.com>
Date: Tue, 8 Oct 2024 17:50:50 +0200
Subject: [PATCH] index.md

---
 docs/index.md | 9 +++++----
 1 file changed, 5 insertions(+), 4 deletions(-)

diff --git a/docs/index.md b/docs/index.md
index a43494f..9193d4e 100644
--- a/docs/index.md
+++ b/docs/index.md
@@ -19,10 +19,11 @@ We are developing a novel approach that exploits the ability of the UPS to more
 
 ## Our Workflow
 1. Identification of reprogrammable E3 ligases and clinically relevant protein targets.
-2. Construction of a E3-ligase activity driven Phage-Assisted Continous Evolution (PACE) system
-3. Evolution of the E3 ligase towards recognising clinically relevant protein targets
-4. Confirmation of evolved E3 activity in bacterial systems and mammalian cell lines
-5. Further work towards clinical use of the evolved E3 ligase for Targeted Protein Degradation.
+2. Construct selection system and test different promoters, linkers, substrates, among other things.
+3. Achieve E3 ligase activity dependent phage propagation in the selection system.
+4. Evolution of the E3 ligase towards recognising clinically relevant protein targets using Phage-Assisted Continous Evolution (PACE).
+5. Confirmation of evolved E3 activity in bacterial system and mammalian cell lines.
+6. Further work towards clinical use of the evolved E3 ligase for Targeted Protein Degradation.
 
 ## Key achievements: