Skip to content

Commit

Permalink
Update index.md
Browse files Browse the repository at this point in the history
  • Loading branch information
BlueShark002 authored Oct 7, 2024
1 parent 8252519 commit 3b8a9e1
Showing 1 changed file with 1 addition and 1 deletion.
2 changes: 1 addition & 1 deletion docs/index.md
Original file line number Diff line number Diff line change
Expand Up @@ -8,4 +8,4 @@ Extremophiles, known for their ability to thrive in extreme environments, are va
In response, we developed iExtreme, a comprehensive database containing 1,030 genomes of extremophiles across three categories, alongside a deep learning method for their identification. This method achieved an accuracy of up to 0.99 in predicting extremophile living conditions. Through **iExtreme**, we identified 520 previously unknown extremophilic species and 4,419 extremophilic genomes from various databases. Additionally, we utilized structure-based clustering to discover novel D-psicose 3-epimerases (DPEase) and α-amylases. To further enhance enzyme activity, we developed a directed evolution method using phage-assisted non-continuous evolution in droplets. The evolved DPEase demonstrated a 3-fold increase in activity, a 5.4-fold extension in half-life, and achieved the highest reported yield of 243 g/L D-allulose.


<center>![home](./img/home.png)</center>
<center><img src="./img/home.png"></img></center>

0 comments on commit 3b8a9e1

Please sign in to comment.