diff --git a/sycl/test-e2e/lit.cfg.py b/sycl/test-e2e/lit.cfg.py
index c0e9f9c926c20..1ba4d04acb853 100644
--- a/sycl/test-e2e/lit.cfg.py
+++ b/sycl/test-e2e/lit.cfg.py
@@ -6,6 +6,7 @@
 import re
 import subprocess
 import textwrap
+import shlex
 import shutil
 
 import lit.formats
@@ -304,12 +305,18 @@ def open_check_file(file_name):
         file=fp,
     )
 
-config.level_zero_libs_dir = lit_config.params.get(
-    "level_zero_libs_dir", config.level_zero_libs_dir
+config.level_zero_libs_dir = shlex.quote(
+    lit_config.params.get("level_zero_libs_dir", config.level_zero_libs_dir)
 )
-config.level_zero_include = lit_config.params.get(
-    "level_zero_include",
-    (config.level_zero_include if config.level_zero_include else config.sycl_include),
+config.level_zero_include = shlex.quote(
+    lit_config.params.get(
+        "level_zero_include",
+        (
+            config.level_zero_include
+            if config.level_zero_include
+            else config.sycl_include
+        ),
+    )
 )
 
 level_zero_options = level_zero_options = (
@@ -409,10 +416,14 @@ def open_check_file(file_name):
         file=fp,
     )
 
-config.cuda_libs_dir = lit_config.params.get("cuda_libs_dir", config.cuda_libs_dir)
-config.cuda_include = lit_config.params.get(
-    "cuda_include",
-    (config.cuda_include if config.cuda_include else config.sycl_include),
+config.cuda_libs_dir = shlex.quote(
+    lit_config.params.get("cuda_libs_dir", config.cuda_libs_dir)
+)
+config.cuda_include = shlex.quote(
+    lit_config.params.get(
+        "cuda_include",
+        (config.cuda_include if config.cuda_include else config.sycl_include),
+    )
 )
 
 cuda_options = cuda_options = (
@@ -454,10 +465,14 @@ def open_check_file(file_name):
         ),
         file=fp,
     )
-config.hip_libs_dir = lit_config.params.get("hip_libs_dir", config.hip_libs_dir)
-config.hip_include = lit_config.params.get(
-    "hip_include",
-    (config.hip_include if config.hip_include else config.sycl_include),
+config.hip_libs_dir = shlex.quote(
+    lit_config.params.get("hip_libs_dir", config.hip_libs_dir)
+)
+config.hip_include = shlex.quote(
+    lit_config.params.get(
+        "hip_include",
+        (config.hip_include if config.hip_include else config.sycl_include),
+    )
 )
 
 hip_options = hip_options = (