From 4aed4868b300948e736889aef2454f1bb02ad3ca Mon Sep 17 00:00:00 2001
From: Ivan William Harsono <ivanwilliam.md@gmail.com>
Date: Wed, 10 Apr 2024 14:32:53 +0700
Subject: [PATCH] added example with exomiser_html_clinical_report

---
 example/example_pipeline_both.sh              |   249 +-
 example/example_pipeline_solo.sh              |   249 +-
 example/example_pipeline_trio.sh              |   249 +-
 ...L04_B5EHOMdmhwXAAAA-515-exomiser-solo.html |  9871 ++++++++++++
 ...L04_B5EHOMdmhwXAAAA-515-exomiser-trio.html | 12976 ++++++++++++++++
 example/iderare_example.yml                   |    44 +-
 6 files changed, 23248 insertions(+), 390 deletions(-)
 create mode 100644 example/exomiser_html_clinical_report/V350145665_L04_B5EHOMdmhwXAAAA-515-exomiser-solo.html
 create mode 100644 example/exomiser_html_clinical_report/V350145665_L04_B5EHOMdmhwXAAAA-515-exomiser-trio.html

diff --git a/example/example_pipeline_both.sh b/example/example_pipeline_both.sh
index 06729a4..7f6ce5c 100644
--- a/example/example_pipeline_both.sh
+++ b/example/example_pipeline_both.sh
@@ -141,14 +141,14 @@ echo "STEP 1: QC - Run fastqp - Optional (if the input is raw untrimmed fastq)"
 if [ ! -z "$proband_name" ] && [ "$trimming" = true ]; then
     echo "STEP 1a : Proband"
 
-    if [ -f ${FASTQ_DIR}/${proband_name}_1.fastq ] && [ -f ${FASTQ_DIR}/${proband_name}_2.fastq ]; then
+    if [ -f "${FASTQ_DIR}/${proband_name}_1.fastq" ] && [ -f "${FASTQ_DIR}/${proband_name}_2.fastq" ]; then
         echo "Raw fastq exist, continue to Trimming"
     else
         echo "File not exist, please check the input directory"
         exit 1
     fi
 
-    if [ -f ${FASTQ_DIR}/${proband_name}_1.fq.gz ] && [ -f ${FASTQ_DIR}/${proband_name}_2.fq.gz ]; then
+    if [ -f "${FASTQ_DIR}/${proband_name}_1.fq.gz" ] && [ -f "${FASTQ_DIR}/${proband_name}_2.fq.gz" ]; then
         echo "Output fq.qz exist, skipping Trimming"
     else
         echo "File not exist, continue to Trimming"
@@ -169,14 +169,14 @@ fi
 if [ ! -z "$mother_name" ] && [ "$trimming" = true ] && [ "$trio_analysis" = true ]; then
     echo "STEP 1b : Mother"
     
-    if [ -f ${FASTQ_DIR}/${mother_name}_1.fastq ] && [ -f ${FASTQ_DIR}/${mother_name}_2.fastq ]; then
+    if [ -f "${FASTQ_DIR}/${mother_name}_1.fastq" ] && [ -f "${FASTQ_DIR}/${mother_name}_2.fastq" ]; then
         echo "Raw fastq exist, continue to Trimming"
     else
         echo "File not exist, please check the input directory"
         exit 1
     fi
 
-    if [ -f ${FASTQ_DIR}/${mother_name}_1.fq.gz ] && [ -f ${FASTQ_DIR}/${mother_name}_2.fq.gz ]; then
+    if [ -f "${FASTQ_DIR}/${mother_name}_1.fq.gz" ] && [ -f "${FASTQ_DIR}/${mother_name}_2.fq.gz" ]; then
         echo "Output fq.qz exist, skipping Trimming"
     else
         echo "File not exist, continue to Trimming"
@@ -197,14 +197,14 @@ fi
 if [ ! -z "$father_name" ] && [ "$trimming" = true ] && [ "$trio_analysis" = true ]; then
     echo "STEP 1C : Father"
     
-    if [ -f ${FASTQ_DIR}/${father_name}_1.fastq ] && [ -f ${FASTQ_DIR}/${father_name}_2.fastq ]; then
+    if [ -f "${FASTQ_DIR}/${father_name}_1.fastq" ] && [ -f "${FASTQ_DIR}/${father_name}_2.fastq" ]; then
         echo "Raw fastq exist, continue to Trimming"
     else
         echo "File not exist, please check the input directory"
         exit 1
     fi
 
-    if [ -f ${FASTQ_DIR}/${father_name}_1.fq.gz ] && [ -f ${FASTQ_DIR}/${father_name}_2.fq.gz ]; then
+    if [ -f "${FASTQ_DIR}/${father_name}_1.fq.gz" ] && [ -f "${FASTQ_DIR}/${father_name}_2.fq.gz" ]; then
         echo "Output fq.qz exist, skipping Trimming"
     else
         echo "File not exist, continue to Trimming"
@@ -230,14 +230,14 @@ echo "STEP 2: Map to reference using BWA-MEM2"
 if [ ! -z "$proband_name" ]; then
     echo "STEP 2a : Proband"
 
-    if [ -f ${FASTQ_DIR}/${proband_name}_1.fq.gz ] && [ -f ${FASTQ_DIR}/${proband_name}_2.fq.gz ]; then
+    if [ -f "${FASTQ_DIR}/${proband_name}_1.fq.gz" ] && [ -f "${FASTQ_DIR}/${proband_name}_2.fq.gz" ]; then
         echo "Paired end fq.qz exist, continue to BWA-MEM2"
     else
         echo "File not exist, please check the input directory"
         exit 1
     fi
 
-    if [-f ${SAM_DIR}/${proband_name}_raw.sam ] || [ -f ${INPUT_DIR}/${proband_name}.bam ]; then
+    if [-f "${SAM_DIR}/${proband_name}_raw.sam" ] || [ -f "${INPUT_DIR}/${proband_name}.bam" ]; then
         echo "SAM file or final BAM file exist, skipping BWA-MEM2"
     else
         # BWA MEM2 Alignment
@@ -255,14 +255,14 @@ fi
 if [ ! -z "$mother_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 2b : Mother"
 
-    if [ -f ${FASTQ_DIR}/${mother_name}_1.fq.gz ] && [ -f ${FASTQ_DIR}/${mother_name}_2.fq.gz ]; then
+    if [ -f "${FASTQ_DIR}/${mother_name}_1.fq.gz" ] && [ -f "${FASTQ_DIR}/${mother_name}_2.fq.gz" ]; then
         echo "Paired end fq.qz exist, continue to BWA-MEM2"
     else
         echo "File not exist, please check the input directory"
         exit 1
     fi
     
-    if [-f ${SAM_DIR}/${mother_name}_raw.sam ] || [ -f ${INPUT_DIR}/${mother_name}.bam ]; then
+    if [-f "${SAM_DIR}/${mother_name}_raw.sam" ] || [ -f "${INPUT_DIR}/${mother_name}.bam" ]; then
         echo "SAM file or final BAM file exist, skipping BWA-MEM2"
     else
         # BWA MEM2 Alignment
@@ -280,14 +280,14 @@ fi
 if [ ! -z "$father_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 2c : Father"
     
-    if [ -f ${FASTQ_DIR}/${father_name}_1.fq.gz ] && [ -f ${FASTQ_DIR}/${father_name}_2.fq.gz ]; then
+    if [ -f "${FASTQ_DIR}/${father_name}_1.fq.gz" ] && [ -f "${FASTQ_DIR}/${father_name}_2.fq.gz" ]; then
         echo "Paired end fq.qz exist, continue to BWA-MEM2"
     else
         echo "File not exist, please check the input directory"
         exit 1
     fi
 
-    if [-f ${SAM_DIR}/${father_name}_raw.sam ] || [ -f ${INPUT_DIR}/${father_name}.bam ]; then
+    if [-f "${SAM_DIR}/${father_name}_raw.sam" ] || [ -f "${INPUT_DIR}/${father_name}.bam" ]; then
         echo "SAM file or final BAM file exist, skipping BWA-MEM2"
     else
         # BWA MEM2 Alignment
@@ -312,7 +312,7 @@ echo "STEP 3: Mark Duplicates and Sort - Sambamba"
 if [ ! -z "$proband_name" ]; then
     echo "STEP 3a : Proband"
 
-    if [ -f ${INPUT_DIR}/${proband_name}.bam ]; then
+    if [ -f "${INPUT_DIR}/${proband_name}.bam" ]; then
         echo "Final BAM file exist, skipping Mark Duplicates and Sort"
     else
         sambamba view -p -t=$(nproc) -l=9 \
@@ -333,7 +333,7 @@ fi
 if [ ! -z "$mother_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 3b : Mother"
 
-    if [ -f ${INPUT_DIR}/${mother_name}.bam ]; then
+    if [ -f "${INPUT_DIR}/${mother_name}.bam" ]; then
         echo "Final BAM file exist, skipping Mark Duplicates and Sort"
     else
         sambamba view -p -t=$(nproc) -l=9 \
@@ -354,7 +354,7 @@ fi
 if [ ! -z "$father_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 3c : Father"
     
-    if [ -f ${INPUT_DIR}/${father_name}.bam ]; then
+    if [ -f "${INPUT_DIR}/${father_name}.bam" ]; then
         echo "Final BAM file exist, skipping Mark Duplicates and Sort"
     else
         sambamba view -p -t=$(nproc) -l=9 \
@@ -373,13 +373,13 @@ fi
 
 ### Remove Intermediate SAM BAM file as it consumes too much spaces
 
-#### Remove all in one folder 
-rm ${SAM_DIR}/*.sam ${SAM_DIR}/*.bam
-
-#### Remove one by one
-rm ${SAM_DIR}/${proband_name}_raw.sam ${SAM_DIR}/${mother_name}_raw.sam ${SAM_DIR}/${father_name}_raw.sam
-rm ${SAM_DIR}/${proband_name}_raw.bam ${SAM_DIR}/${mother_name}_raw.bam ${SAM_DIR}/${father_name}_raw.bam
-rm ${SAM_DIR}/${proband_name}_dedup.bam ${SAM_DIR}/${mother_name}_dedup.bam ${SAM_DIR}/${father_name}_dedup.bam
+# Check if the directory exists
+if [ -d "$SAM_DIR" ]; then
+    echo "Remove all data inside SAM directory to save harddisk space"
+    rm -r "$SAM_DIR"
+else
+    echo "Directory $SAM_DIR does not exist."
+fi
 
 # ----------------------------------------------
 # STEP 4: Variant Calling
@@ -389,8 +389,8 @@ if [ ! -z "$proband_name" ] && [ "$solo_analysis" = true ]; then
     echo "STEP 4a: Variant Calling Proband DeepVariant"
 
     # Further check if ${INPUT_DIR}/${proband_name}.bam all exists
-    if [ -f ${INPUT_DIR}/${proband_name}.bam ]; then
-        if [ -f ${OUTPUT_DIR}/${proband_name}_proband.vcf.gz]; then
+    if [ -f "${INPUT_DIR}/${proband_name}.bam" ]; then
+        if [ -f "${OUTPUT_DIR}/${proband_name}_proband.vcf.gz" ]; then
             echo "VCF file exist, skipping DeepVariant"
         else
             echo "BAM file exist, continue to DeepVariant"
@@ -425,9 +425,9 @@ if [ ! -z "$proband_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 4b: Variant Calling DeepTrio"
 
     # Further check if ${INPUT_DIR}/${father_name}.bam and ${INPUT_DIR}/${mother_name}.bam and ${INPUT_DIR}/${proband_name}.bam all exists
-    if [ -f ${INPUT_DIR}/${father_name}.bam ] && [ -f ${INPUT_DIR}/${mother_name}.bam ] && [ -f ${INPUT_DIR}/${proband_name}.bam ]; then
+    if [ -f "${INPUT_DIR}/${father_name}.bam" ] && [ -f "${INPUT_DIR}/${mother_name}.bam" ] && [ -f "${INPUT_DIR}/${proband_name}.bam" ]; then
 
-        if [ -f ${OUTPUT_DIR}/${proband_name}.g.vcf.gz] && [ -f ${OUTPUT_DIR}/${father_name}.g.vcf.gz] && [ -f ${OUTPUT_DIR}/${mother_name}.g.vcf.gz]; then
+        if [ -f "${OUTPUT_DIR}/${proband_name}.g.vcf.gz" ] && [ -f "${OUTPUT_DIR}/${father_name}.g.vcf.gz" ] && [ -f "${OUTPUT_DIR}/${mother_name}.g.vcf.gz" ]; then
             echo "gVCF file exist, skipping DeepTrio"
         else
             echo "All BAM files exist, continue to DeepTrio"
@@ -474,7 +474,7 @@ fi
 if [ ! -z "$proband_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 5: Merge gVCF files with GLnexus"
 
-    if [ -f ${OUTPUT_DIR}/${proband_name}_trio_merged.vcf.gz ]; then
+    if [ -f "${OUTPUT_DIR}/${proband_name}_trio_merged.vcf.gz" ]; then
         echo "Merged VCF file exist, skipping GLnexus"
     else
         docker run \
@@ -498,22 +498,22 @@ if [ ! -z "$proband_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 6: Calculate Mendelian Violation Rate using RTG Tools"
     #### Reference : https://www.animalgenome.org/bioinfo/resources/manuals/RTGOperationsManual.pdf
 
-    if [ -d ${REFERENCE_DIR}/${REFSEQ_FASTA}.sdf ];
-    then
-        echo "${REFERENCE_DIR}/${REFSEQ_FASTA}.sdf exists. Removing directory."
-        rm -r -f ${REFERENCE_DIR}/${REFSEQ_FASTA}.sdf
-    else
-        echo "${REFERENCE_DIR}/${REFSEQ_FASTA}.sdf directory does not exist. Continue"
-    fi
 
-    if [ -f ${OUTPUT_DIR}/${proband_name}_trio_merged.vcf.gz ]; then
+    if [ -f "${OUTPUT_DIR}/${proband_name}_trio_merged.vcf.gz" ]; then
         echo "Merged VCF file exist, continue to RTG Tools"
 
-        docker run \
-            -v "${INPUT_DIR}":"/input" \
-            -v "${REFERENCE_DIR}":"/reference" \
-            realtimegenomics/rtg-tools format \
-            -o /reference/${REFSEQ_FASTA}.sdf "/reference/${REFSEQ_FASTA}"
+        if [ -d ${REFERENCE_DIR}/${REFSEQ_FASTA}.sdf ];
+        then
+            echo "${REFERENCE_DIR}/${REFSEQ_FASTA}.sdf exists. Didn't create sdf."
+        else
+            echo "${REFERENCE_DIR}/${REFSEQ_FASTA}.sdf directory does not exist. Creating it"
+            docker run \
+                -v "${INPUT_DIR}":"/input" \
+                -v "${REFERENCE_DIR}":"/reference" \
+                realtimegenomics/rtg-tools format \
+                -o /reference/${REFSEQ_FASTA}.sdf "/reference/${REFSEQ_FASTA}"
+        fi
+
 
         docker run \
             -v "${INPUT_DIR}":"/input" \
@@ -543,9 +543,9 @@ if [ ! -z "$proband_name" ] && [ "$trio_analysis" = true ]; then
         echo "Merged VCF file not exist, please check the input directory"
         exit 1
     fi
-    
+fi
 
-elif [ ! -z "$proband_name" ] && [ "$solo_analysis" = true ]; then
+if [ ! -z "$proband_name" ] && [ "$solo_analysis" = true ]; then
     echo "SKIPPED STEP 5: Merge gVCF files with GLnexus, due to solo analysis (Trio)"
     echo "SKIPPED STEP 6: Calculate Mendelian Violation Rate using RTG Tools (Trio)"
 fi
@@ -559,82 +559,82 @@ fi
 if [ ! -z "$proband_name" ] && [ "$solo_analysis" = true ]; then
     echo "STEP 7a: Annotate Variants Proband - SNPEff with latest database, SnpSift ClinVar, SnpSift dbNSFP"
     
-    if [ ! -f ${OUTPUT_DIR}/${proband_name}_proband.vcf.gz] :
+    if [ ! -f "${OUTPUT_DIR}/${proband_name}_proband.vcf.gz" ]; then
         echo "VCF file not exist, please check the input directory"
         exit 1
     fi
 
     # If output file not exist, run annotate
-    if [ ! -f ${proband_name}-converted-deepVariant.vcf] && [ ! -f ${proband_name}-converted-deepVariant.vcf.gz]:
+    if [ ! -f "${proband_name}-converted-deepVariant.vcf" ] && [ ! -f "${proband_name}-converted-deepVariant.vcf.gz" ]; then
         # Create GATK > dbnsfp Chromosome
         bcftools annotate \
-            --rename-chrs ${chr_rename} \
-            --threads nproc -Oz \
-            -o ${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf \
-            ${OUTPUT_DIR}/${proband_name}_proband.vcf.gz
+            --rename-chrs "${chr_rename}" \
+            --threads "$(nproc)" -Oz \
+            -o "${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf" \
+            "${OUTPUT_DIR}/${proband_name}_proband.vcf.gz"
     else
-        echo "Deepvariant converted VCF file exist, skipping conversion"
+        echo "Deepvariant converted VCF file exists, skipping conversion"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf.gz] && [ -f ${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf] :
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf.gz" ] && [ -f "${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf" ]; then
         # SnpEff with recent GRCh38.p14 database
-        SnpEff -v ${snpEff_ver} -dataDir ${snpEff_dir} \
-            -s ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.html \
-            ${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf
+        SnpEff -v "${snpEff_ver}" -dataDir "${snpEff_dir}" \
+            -s "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.html" \
+            "${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf"
     else
-        echo "SnpEff VCF file exist, skipping SnpEff"
+        echo "SnpEff VCF file exists, skipping SnpEff"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf.gz] && [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf] :
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf.gz" ] && [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf" ]; then
         # SnpSift Annotate ClinVar
-        SnpSift annotate -v ${dbSNP} \
-            ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf
+        SnpSift annotate -v "${dbSNP}" \
+            "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf"
     else
-        echo "Annotated dbSNP file exist, skipping annotation"
+        echo "Annotated dbSNP file exists, skipping annotation"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf.gz] && [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf] :
-        SnpSift annotate -v ${ClinVar} \
-            ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf.gz" ] && [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf" ]; then
+        SnpSift annotate -v "${ClinVar}" \
+            "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf"
     else
-        echo "Annotated ClinVar file exist, skipping annotation"
+        echo "Annotated ClinVar file exists, skipping annotation"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf.gz] && [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf] :
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf.gz" ] && [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf" ]; then
         # Annotate using dbNSFP for SNP Only (Indel Give 0 Annotation Result)
-        SnpSift dbnsfp -v -db ${dbnsfp} \
-            ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf
+        SnpSift dbnsfp -v -db "${dbnsfp}" \
+            "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf"
     else
-        echo "Annotated dbNSFP file exist, skipping annotation"
+        echo "Annotated dbNSFP file exists, skipping annotation"
     fi
 
     # Compress file size using bgzip if the previous .vcf file exist
-    if [ -f ${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf] && [ ! -f ${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf.gz]: 
-        bgzip --threads nproc ${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf
+    if [ -f "${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf" ] && [ ! -f "${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf"
     fi
 fi
 
@@ -644,86 +644,87 @@ if [ ! -z "$proband_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 7b: Annotate Variants Trio - SNP Sift"
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf] && [ ! -f ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf.gz]:
+    if [ ! -f "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf" ] && [ ! -f "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf.gz" ]; then
         # Create GATK > dbnsfp Chromosome
         bcftools annotate \
-            --rename-chrs ${chr_rename} \
-            --threads nproc -Oz \
-            -o ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf \
-            ${OUTPUT_DIR}/${proband_name}_trio_annotated.output.vcf.gz
+            --rename-chrs "${chr_rename}" \
+            --threads "$(nproc)" -Oz \
+            -o "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf" \
+            "${OUTPUT_DIR}/${proband_name}_trio_annotated.output.vcf.gz"
     else
-        echo "DeepTrio converted VCF file exist, skipping conversion"
+        echo "DeepTrio converted VCF file exists, skipping conversion"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf.gz] && [ -f ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf] :
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf.gz" ] && [ -f "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf" ]; then
         # SnpEff with recent GRCh38.p14 database
-        SnpEff -v ${snpEff_ver} -dataDir ${snpEff_dir} \
-            -s ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.html \
-            ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf
+        SnpEff -v "${snpEff_ver}" -dataDir "${snpEff_dir}" \
+            -s "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.html" \
+            "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf"
     else
-        echo "SnpEff VCF file exist, skipping SnpEff"
+        echo "SnpEff VCF file exists, skipping SnpEff"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf.gz] && [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf] :
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf.gz" ] && [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf" ]; then
         # SnpSift
-        SnpSift annotate -v ${dbSNP} \
-            ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf
+        SnpSift annotate -v "${dbSNP}" \
+            "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf"
     else
-        echo "Annotated dbSNP file exist, skipping annotation"
+        echo "Annotated dbSNP file exists, skipping annotation"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf.gz] && [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf] :
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf.gz" ] && [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf" ]; then
         # SnpSift Annotate ClinVar
-        SnpSift annotate -v ${ClinVar} \
-            ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf
+        SnpSift annotate -v "${ClinVar}" \
+            "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf"
     else
-        echo "Annotated ClinVar file exist, skipping annotation"
+        echo "Annotated ClinVar file exists, skipping annotation"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf.gz] && [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf] :
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf.gz" ] && [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf" ]; then
         # Annotate using dbNSFP for SNP Only (Indel Give 0 Annotation Result)
-        SnpSift dbnsfp -v -db ${dbnsfp} \
-            ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf
+        SnpSift dbnsfp -v -db "${dbnsfp}" \
+            "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf"
     else
-        echo "Annotated dbNSFP file exist, skipping annotation"
+        echo "Annotated dbNSFP file exists, skipping annotation"
     fi
 
     # Compress file size using bgzip if the previous .vcf file exist
-    if [ -f ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf] && [ ! -f ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf.gz]: 
-        bgzip --threads nproc ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf
+    if [ -f "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf" ] && [ ! -f "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf"
     fi
+fi
 
 # Additional SV Step using Tiddit @ SV_DIR
 
-# Check if proband_name is not null
-if [ ! -z "$proband_name" ]; then
+# Check if proband_name is not null and annotated tiddit output is not yet exist in folder
+if [ ! -z "$proband_name" ] && [ ! -f "${SV_DIR}/output.filtered.dbnsfp.vcf" ]; then
     echo "STEP 8: SV calling using Tiddit, SnpEff annotation, SnpSift dbNSFP annotation"
 
-    if [ -f ${INPUT_DIR}/${proband_name}.bam ]; then
+    if [ -f "${INPUT_DIR}/${proband_name}.bam" ]; then
         echo "Final BAM file exist, continue to Tiddit"
         docker run \
             -v "${INPUT_DIR}":"/input"   \
@@ -752,6 +753,8 @@ if [ ! -z "$proband_name" ]; then
         echo "BAM file not exist, please check the input directory"
         exit 1
     fi
+else
+    echo "SV output folder exist, and there are already final data, skipping Tiddit"  
 fi
 
 # Step using Exomiser @ Exomiser root folder
@@ -764,12 +767,12 @@ fi
 
 # Check if trio_analysis is true
 if [ "$trio_analysis" = true ]; then
-    echo "STEP 9: Exomiser SNP Solo Trio Analysis"
+    echo "STEP 9: Exomiser SNP Trio Analysis"
     exomiser --analysis ${exomiser_trio}
 fi
 
 # Check if SV VCF is true
-if [ -f ${SV_DIR}/output.filtered.dbnsfp.vcf ]; then
-    echo "STEP 9: Exomiser SV Solo Trio Analysis"
+if [ -f "${SV_DIR}/output.filtered.dbnsfp.vcf" ]; then
+    echo "STEP 9: Exomiser SV Solo Analysis"
     exomiser --analysis ${exomiser_solo_sv}
 fi
\ No newline at end of file
diff --git a/example/example_pipeline_solo.sh b/example/example_pipeline_solo.sh
index 08f1aa1..9047eef 100644
--- a/example/example_pipeline_solo.sh
+++ b/example/example_pipeline_solo.sh
@@ -141,14 +141,14 @@ echo "STEP 1: QC - Run fastqp - Optional (if the input is raw untrimmed fastq)"
 if [ ! -z "$proband_name" ] && [ "$trimming" = true ]; then
     echo "STEP 1a : Proband"
 
-    if [ -f ${FASTQ_DIR}/${proband_name}_1.fastq ] && [ -f ${FASTQ_DIR}/${proband_name}_2.fastq ]; then
+    if [ -f "${FASTQ_DIR}/${proband_name}_1.fastq" ] && [ -f "${FASTQ_DIR}/${proband_name}_2.fastq" ]; then
         echo "Raw fastq exist, continue to Trimming"
     else
         echo "File not exist, please check the input directory"
         exit 1
     fi
 
-    if [ -f ${FASTQ_DIR}/${proband_name}_1.fq.gz ] && [ -f ${FASTQ_DIR}/${proband_name}_2.fq.gz ]; then
+    if [ -f "${FASTQ_DIR}/${proband_name}_1.fq.gz" ] && [ -f "${FASTQ_DIR}/${proband_name}_2.fq.gz" ]; then
         echo "Output fq.qz exist, skipping Trimming"
     else
         echo "File not exist, continue to Trimming"
@@ -169,14 +169,14 @@ fi
 if [ ! -z "$mother_name" ] && [ "$trimming" = true ] && [ "$trio_analysis" = true ]; then
     echo "STEP 1b : Mother"
     
-    if [ -f ${FASTQ_DIR}/${mother_name}_1.fastq ] && [ -f ${FASTQ_DIR}/${mother_name}_2.fastq ]; then
+    if [ -f "${FASTQ_DIR}/${mother_name}_1.fastq" ] && [ -f "${FASTQ_DIR}/${mother_name}_2.fastq" ]; then
         echo "Raw fastq exist, continue to Trimming"
     else
         echo "File not exist, please check the input directory"
         exit 1
     fi
 
-    if [ -f ${FASTQ_DIR}/${mother_name}_1.fq.gz ] && [ -f ${FASTQ_DIR}/${mother_name}_2.fq.gz ]; then
+    if [ -f "${FASTQ_DIR}/${mother_name}_1.fq.gz" ] && [ -f "${FASTQ_DIR}/${mother_name}_2.fq.gz" ]; then
         echo "Output fq.qz exist, skipping Trimming"
     else
         echo "File not exist, continue to Trimming"
@@ -197,14 +197,14 @@ fi
 if [ ! -z "$father_name" ] && [ "$trimming" = true ] && [ "$trio_analysis" = true ]; then
     echo "STEP 1C : Father"
     
-    if [ -f ${FASTQ_DIR}/${father_name}_1.fastq ] && [ -f ${FASTQ_DIR}/${father_name}_2.fastq ]; then
+    if [ -f "${FASTQ_DIR}/${father_name}_1.fastq" ] && [ -f "${FASTQ_DIR}/${father_name}_2.fastq" ]; then
         echo "Raw fastq exist, continue to Trimming"
     else
         echo "File not exist, please check the input directory"
         exit 1
     fi
 
-    if [ -f ${FASTQ_DIR}/${father_name}_1.fq.gz ] && [ -f ${FASTQ_DIR}/${father_name}_2.fq.gz ]; then
+    if [ -f "${FASTQ_DIR}/${father_name}_1.fq.gz" ] && [ -f "${FASTQ_DIR}/${father_name}_2.fq.gz" ]; then
         echo "Output fq.qz exist, skipping Trimming"
     else
         echo "File not exist, continue to Trimming"
@@ -230,14 +230,14 @@ echo "STEP 2: Map to reference using BWA-MEM2"
 if [ ! -z "$proband_name" ]; then
     echo "STEP 2a : Proband"
 
-    if [ -f ${FASTQ_DIR}/${proband_name}_1.fq.gz ] && [ -f ${FASTQ_DIR}/${proband_name}_2.fq.gz ]; then
+    if [ -f "${FASTQ_DIR}/${proband_name}_1.fq.gz" ] && [ -f "${FASTQ_DIR}/${proband_name}_2.fq.gz" ]; then
         echo "Paired end fq.qz exist, continue to BWA-MEM2"
     else
         echo "File not exist, please check the input directory"
         exit 1
     fi
 
-    if [-f ${SAM_DIR}/${proband_name}_raw.sam ] || [ -f ${INPUT_DIR}/${proband_name}.bam ]; then
+    if [-f "${SAM_DIR}/${proband_name}_raw.sam" ] || [ -f "${INPUT_DIR}/${proband_name}.bam" ]; then
         echo "SAM file or final BAM file exist, skipping BWA-MEM2"
     else
         # BWA MEM2 Alignment
@@ -255,14 +255,14 @@ fi
 if [ ! -z "$mother_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 2b : Mother"
 
-    if [ -f ${FASTQ_DIR}/${mother_name}_1.fq.gz ] && [ -f ${FASTQ_DIR}/${mother_name}_2.fq.gz ]; then
+    if [ -f "${FASTQ_DIR}/${mother_name}_1.fq.gz" ] && [ -f "${FASTQ_DIR}/${mother_name}_2.fq.gz" ]; then
         echo "Paired end fq.qz exist, continue to BWA-MEM2"
     else
         echo "File not exist, please check the input directory"
         exit 1
     fi
     
-    if [-f ${SAM_DIR}/${mother_name}_raw.sam ] || [ -f ${INPUT_DIR}/${mother_name}.bam ]; then
+    if [-f "${SAM_DIR}/${mother_name}_raw.sam" ] || [ -f "${INPUT_DIR}/${mother_name}.bam" ]; then
         echo "SAM file or final BAM file exist, skipping BWA-MEM2"
     else
         # BWA MEM2 Alignment
@@ -280,14 +280,14 @@ fi
 if [ ! -z "$father_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 2c : Father"
     
-    if [ -f ${FASTQ_DIR}/${father_name}_1.fq.gz ] && [ -f ${FASTQ_DIR}/${father_name}_2.fq.gz ]; then
+    if [ -f "${FASTQ_DIR}/${father_name}_1.fq.gz" ] && [ -f "${FASTQ_DIR}/${father_name}_2.fq.gz" ]; then
         echo "Paired end fq.qz exist, continue to BWA-MEM2"
     else
         echo "File not exist, please check the input directory"
         exit 1
     fi
 
-    if [-f ${SAM_DIR}/${father_name}_raw.sam ] || [ -f ${INPUT_DIR}/${father_name}.bam ]; then
+    if [-f "${SAM_DIR}/${father_name}_raw.sam" ] || [ -f "${INPUT_DIR}/${father_name}.bam" ]; then
         echo "SAM file or final BAM file exist, skipping BWA-MEM2"
     else
         # BWA MEM2 Alignment
@@ -312,7 +312,7 @@ echo "STEP 3: Mark Duplicates and Sort - Sambamba"
 if [ ! -z "$proband_name" ]; then
     echo "STEP 3a : Proband"
 
-    if [ -f ${INPUT_DIR}/${proband_name}.bam ]; then
+    if [ -f "${INPUT_DIR}/${proband_name}.bam" ]; then
         echo "Final BAM file exist, skipping Mark Duplicates and Sort"
     else
         sambamba view -p -t=$(nproc) -l=9 \
@@ -333,7 +333,7 @@ fi
 if [ ! -z "$mother_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 3b : Mother"
 
-    if [ -f ${INPUT_DIR}/${mother_name}.bam ]; then
+    if [ -f "${INPUT_DIR}/${mother_name}.bam" ]; then
         echo "Final BAM file exist, skipping Mark Duplicates and Sort"
     else
         sambamba view -p -t=$(nproc) -l=9 \
@@ -354,7 +354,7 @@ fi
 if [ ! -z "$father_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 3c : Father"
     
-    if [ -f ${INPUT_DIR}/${father_name}.bam ]; then
+    if [ -f "${INPUT_DIR}/${father_name}.bam" ]; then
         echo "Final BAM file exist, skipping Mark Duplicates and Sort"
     else
         sambamba view -p -t=$(nproc) -l=9 \
@@ -373,13 +373,13 @@ fi
 
 ### Remove Intermediate SAM BAM file as it consumes too much spaces
 
-#### Remove all in one folder 
-rm ${SAM_DIR}/*.sam ${SAM_DIR}/*.bam
-
-#### Remove one by one
-rm ${SAM_DIR}/${proband_name}_raw.sam ${SAM_DIR}/${mother_name}_raw.sam ${SAM_DIR}/${father_name}_raw.sam
-rm ${SAM_DIR}/${proband_name}_raw.bam ${SAM_DIR}/${mother_name}_raw.bam ${SAM_DIR}/${father_name}_raw.bam
-rm ${SAM_DIR}/${proband_name}_dedup.bam ${SAM_DIR}/${mother_name}_dedup.bam ${SAM_DIR}/${father_name}_dedup.bam
+# Check if the directory exists
+if [ -d "$SAM_DIR" ]; then
+    echo "Remove all data inside SAM directory to save harddisk space"
+    rm -r "$SAM_DIR"
+else
+    echo "Directory $SAM_DIR does not exist."
+fi
 
 # ----------------------------------------------
 # STEP 4: Variant Calling
@@ -389,8 +389,8 @@ if [ ! -z "$proband_name" ] && [ "$solo_analysis" = true ]; then
     echo "STEP 4a: Variant Calling Proband DeepVariant"
 
     # Further check if ${INPUT_DIR}/${proband_name}.bam all exists
-    if [ -f ${INPUT_DIR}/${proband_name}.bam ]; then
-        if [ -f ${OUTPUT_DIR}/${proband_name}_proband.vcf.gz]; then
+    if [ -f "${INPUT_DIR}/${proband_name}.bam" ]; then
+        if [ -f "${OUTPUT_DIR}/${proband_name}_proband.vcf.gz" ]; then
             echo "VCF file exist, skipping DeepVariant"
         else
             echo "BAM file exist, continue to DeepVariant"
@@ -425,9 +425,9 @@ if [ ! -z "$proband_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 4b: Variant Calling DeepTrio"
 
     # Further check if ${INPUT_DIR}/${father_name}.bam and ${INPUT_DIR}/${mother_name}.bam and ${INPUT_DIR}/${proband_name}.bam all exists
-    if [ -f ${INPUT_DIR}/${father_name}.bam ] && [ -f ${INPUT_DIR}/${mother_name}.bam ] && [ -f ${INPUT_DIR}/${proband_name}.bam ]; then
+    if [ -f "${INPUT_DIR}/${father_name}.bam" ] && [ -f "${INPUT_DIR}/${mother_name}.bam" ] && [ -f "${INPUT_DIR}/${proband_name}.bam" ]; then
 
-        if [ -f ${OUTPUT_DIR}/${proband_name}.g.vcf.gz] && [ -f ${OUTPUT_DIR}/${father_name}.g.vcf.gz] && [ -f ${OUTPUT_DIR}/${mother_name}.g.vcf.gz]; then
+        if [ -f "${OUTPUT_DIR}/${proband_name}.g.vcf.gz" ] && [ -f "${OUTPUT_DIR}/${father_name}.g.vcf.gz" ] && [ -f "${OUTPUT_DIR}/${mother_name}.g.vcf.gz" ]; then
             echo "gVCF file exist, skipping DeepTrio"
         else
             echo "All BAM files exist, continue to DeepTrio"
@@ -474,7 +474,7 @@ fi
 if [ ! -z "$proband_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 5: Merge gVCF files with GLnexus"
 
-    if [ -f ${OUTPUT_DIR}/${proband_name}_trio_merged.vcf.gz ]; then
+    if [ -f "${OUTPUT_DIR}/${proband_name}_trio_merged.vcf.gz" ]; then
         echo "Merged VCF file exist, skipping GLnexus"
     else
         docker run \
@@ -498,22 +498,22 @@ if [ ! -z "$proband_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 6: Calculate Mendelian Violation Rate using RTG Tools"
     #### Reference : https://www.animalgenome.org/bioinfo/resources/manuals/RTGOperationsManual.pdf
 
-    if [ -d ${REFERENCE_DIR}/${REFSEQ_FASTA}.sdf ];
-    then
-        echo "${REFERENCE_DIR}/${REFSEQ_FASTA}.sdf exists. Removing directory."
-        rm -r -f ${REFERENCE_DIR}/${REFSEQ_FASTA}.sdf
-    else
-        echo "${REFERENCE_DIR}/${REFSEQ_FASTA}.sdf directory does not exist. Continue"
-    fi
 
-    if [ -f ${OUTPUT_DIR}/${proband_name}_trio_merged.vcf.gz ]; then
+    if [ -f "${OUTPUT_DIR}/${proband_name}_trio_merged.vcf.gz" ]; then
         echo "Merged VCF file exist, continue to RTG Tools"
 
-        docker run \
-            -v "${INPUT_DIR}":"/input" \
-            -v "${REFERENCE_DIR}":"/reference" \
-            realtimegenomics/rtg-tools format \
-            -o /reference/${REFSEQ_FASTA}.sdf "/reference/${REFSEQ_FASTA}"
+        if [ -d ${REFERENCE_DIR}/${REFSEQ_FASTA}.sdf ];
+        then
+            echo "${REFERENCE_DIR}/${REFSEQ_FASTA}.sdf exists. Didn't create sdf."
+        else
+            echo "${REFERENCE_DIR}/${REFSEQ_FASTA}.sdf directory does not exist. Creating it"
+            docker run \
+                -v "${INPUT_DIR}":"/input" \
+                -v "${REFERENCE_DIR}":"/reference" \
+                realtimegenomics/rtg-tools format \
+                -o /reference/${REFSEQ_FASTA}.sdf "/reference/${REFSEQ_FASTA}"
+        fi
+
 
         docker run \
             -v "${INPUT_DIR}":"/input" \
@@ -543,9 +543,9 @@ if [ ! -z "$proband_name" ] && [ "$trio_analysis" = true ]; then
         echo "Merged VCF file not exist, please check the input directory"
         exit 1
     fi
-    
+fi
 
-elif [ ! -z "$proband_name" ] && [ "$solo_analysis" = true ]; then
+if [ ! -z "$proband_name" ] && [ "$solo_analysis" = true ]; then
     echo "SKIPPED STEP 5: Merge gVCF files with GLnexus, due to solo analysis (Trio)"
     echo "SKIPPED STEP 6: Calculate Mendelian Violation Rate using RTG Tools (Trio)"
 fi
@@ -559,82 +559,82 @@ fi
 if [ ! -z "$proband_name" ] && [ "$solo_analysis" = true ]; then
     echo "STEP 7a: Annotate Variants Proband - SNPEff with latest database, SnpSift ClinVar, SnpSift dbNSFP"
     
-    if [ ! -f ${OUTPUT_DIR}/${proband_name}_proband.vcf.gz] :
+    if [ ! -f "${OUTPUT_DIR}/${proband_name}_proband.vcf.gz" ]; then
         echo "VCF file not exist, please check the input directory"
         exit 1
     fi
 
     # If output file not exist, run annotate
-    if [ ! -f ${proband_name}-converted-deepVariant.vcf] && [ ! -f ${proband_name}-converted-deepVariant.vcf.gz]:
+    if [ ! -f "${proband_name}-converted-deepVariant.vcf" ] && [ ! -f "${proband_name}-converted-deepVariant.vcf.gz" ]; then
         # Create GATK > dbnsfp Chromosome
         bcftools annotate \
-            --rename-chrs ${chr_rename} \
-            --threads nproc -Oz \
-            -o ${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf \
-            ${OUTPUT_DIR}/${proband_name}_proband.vcf.gz
+            --rename-chrs "${chr_rename}" \
+            --threads "$(nproc)" -Oz \
+            -o "${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf" \
+            "${OUTPUT_DIR}/${proband_name}_proband.vcf.gz"
     else
-        echo "Deepvariant converted VCF file exist, skipping conversion"
+        echo "Deepvariant converted VCF file exists, skipping conversion"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf.gz] && [ -f ${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf] :
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf.gz" ] && [ -f "${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf" ]; then
         # SnpEff with recent GRCh38.p14 database
-        SnpEff -v ${snpEff_ver} -dataDir ${snpEff_dir} \
-            -s ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.html \
-            ${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf
+        SnpEff -v "${snpEff_ver}" -dataDir "${snpEff_dir}" \
+            -s "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.html" \
+            "${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf"
     else
-        echo "SnpEff VCF file exist, skipping SnpEff"
+        echo "SnpEff VCF file exists, skipping SnpEff"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf.gz] && [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf] :
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf.gz" ] && [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf" ]; then
         # SnpSift Annotate ClinVar
-        SnpSift annotate -v ${dbSNP} \
-            ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf
+        SnpSift annotate -v "${dbSNP}" \
+            "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf"
     else
-        echo "Annotated dbSNP file exist, skipping annotation"
+        echo "Annotated dbSNP file exists, skipping annotation"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf.gz] && [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf] :
-        SnpSift annotate -v ${ClinVar} \
-            ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf.gz" ] && [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf" ]; then
+        SnpSift annotate -v "${ClinVar}" \
+            "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf"
     else
-        echo "Annotated ClinVar file exist, skipping annotation"
+        echo "Annotated ClinVar file exists, skipping annotation"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf.gz] && [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf] :
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf.gz" ] && [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf" ]; then
         # Annotate using dbNSFP for SNP Only (Indel Give 0 Annotation Result)
-        SnpSift dbnsfp -v -db ${dbnsfp} \
-            ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf
+        SnpSift dbnsfp -v -db "${dbnsfp}" \
+            "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf"
     else
-        echo "Annotated dbNSFP file exist, skipping annotation"
+        echo "Annotated dbNSFP file exists, skipping annotation"
     fi
 
     # Compress file size using bgzip if the previous .vcf file exist
-    if [ -f ${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf] && [ ! -f ${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf.gz]: 
-        bgzip --threads nproc ${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf
+    if [ -f "${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf" ] && [ ! -f "${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf"
     fi
 fi
 
@@ -644,86 +644,87 @@ if [ ! -z "$proband_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 7b: Annotate Variants Trio - SNP Sift"
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf] && [ ! -f ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf.gz]:
+    if [ ! -f "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf" ] && [ ! -f "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf.gz" ]; then
         # Create GATK > dbnsfp Chromosome
         bcftools annotate \
-            --rename-chrs ${chr_rename} \
-            --threads nproc -Oz \
-            -o ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf \
-            ${OUTPUT_DIR}/${proband_name}_trio_annotated.output.vcf.gz
+            --rename-chrs "${chr_rename}" \
+            --threads "$(nproc)" -Oz \
+            -o "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf" \
+            "${OUTPUT_DIR}/${proband_name}_trio_annotated.output.vcf.gz"
     else
-        echo "DeepTrio converted VCF file exist, skipping conversion"
+        echo "DeepTrio converted VCF file exists, skipping conversion"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf.gz] && [ -f ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf] :
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf.gz" ] && [ -f "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf" ]; then
         # SnpEff with recent GRCh38.p14 database
-        SnpEff -v ${snpEff_ver} -dataDir ${snpEff_dir} \
-            -s ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.html \
-            ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf
+        SnpEff -v "${snpEff_ver}" -dataDir "${snpEff_dir}" \
+            -s "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.html" \
+            "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf"
     else
-        echo "SnpEff VCF file exist, skipping SnpEff"
+        echo "SnpEff VCF file exists, skipping SnpEff"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf.gz] && [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf] :
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf.gz" ] && [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf" ]; then
         # SnpSift
-        SnpSift annotate -v ${dbSNP} \
-            ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf
+        SnpSift annotate -v "${dbSNP}" \
+            "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf"
     else
-        echo "Annotated dbSNP file exist, skipping annotation"
+        echo "Annotated dbSNP file exists, skipping annotation"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf.gz] && [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf] :
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf.gz" ] && [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf" ]; then
         # SnpSift Annotate ClinVar
-        SnpSift annotate -v ${ClinVar} \
-            ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf
+        SnpSift annotate -v "${ClinVar}" \
+            "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf"
     else
-        echo "Annotated ClinVar file exist, skipping annotation"
+        echo "Annotated ClinVar file exists, skipping annotation"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf.gz] && [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf] :
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf.gz" ] && [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf" ]; then
         # Annotate using dbNSFP for SNP Only (Indel Give 0 Annotation Result)
-        SnpSift dbnsfp -v -db ${dbnsfp} \
-            ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf
+        SnpSift dbnsfp -v -db "${dbnsfp}" \
+            "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf"
     else
-        echo "Annotated dbNSFP file exist, skipping annotation"
+        echo "Annotated dbNSFP file exists, skipping annotation"
     fi
 
     # Compress file size using bgzip if the previous .vcf file exist
-    if [ -f ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf] && [ ! -f ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf.gz]: 
-        bgzip --threads nproc ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf
+    if [ -f "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf" ] && [ ! -f "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf"
     fi
+fi
 
 # Additional SV Step using Tiddit @ SV_DIR
 
-# Check if proband_name is not null
-if [ ! -z "$proband_name" ]; then
+# Check if proband_name is not null and annotated tiddit output is not yet exist in folder
+if [ ! -z "$proband_name" ] && [ ! -f "${SV_DIR}/output.filtered.dbnsfp.vcf" ]; then
     echo "STEP 8: SV calling using Tiddit, SnpEff annotation, SnpSift dbNSFP annotation"
 
-    if [ -f ${INPUT_DIR}/${proband_name}.bam ]; then
+    if [ -f "${INPUT_DIR}/${proband_name}.bam" ]; then
         echo "Final BAM file exist, continue to Tiddit"
         docker run \
             -v "${INPUT_DIR}":"/input"   \
@@ -752,6 +753,8 @@ if [ ! -z "$proband_name" ]; then
         echo "BAM file not exist, please check the input directory"
         exit 1
     fi
+else
+    echo "SV output folder exist, and there are already final data, skipping Tiddit"  
 fi
 
 # Step using Exomiser @ Exomiser root folder
@@ -764,12 +767,12 @@ fi
 
 # Check if trio_analysis is true
 if [ "$trio_analysis" = true ]; then
-    echo "STEP 9: Exomiser SNP Solo Trio Analysis"
+    echo "STEP 9: Exomiser SNP Trio Analysis"
     exomiser --analysis ${exomiser_trio}
 fi
 
 # Check if SV VCF is true
-if [ -f ${SV_DIR}/output.filtered.dbnsfp.vcf ]; then
-    echo "STEP 9: Exomiser SV Solo Trio Analysis"
+if [ -f "${SV_DIR}/output.filtered.dbnsfp.vcf" ]; then
+    echo "STEP 9: Exomiser SV Solo Analysis"
     exomiser --analysis ${exomiser_solo_sv}
 fi
\ No newline at end of file
diff --git a/example/example_pipeline_trio.sh b/example/example_pipeline_trio.sh
index b711ff6..01c379c 100644
--- a/example/example_pipeline_trio.sh
+++ b/example/example_pipeline_trio.sh
@@ -141,14 +141,14 @@ echo "STEP 1: QC - Run fastqp - Optional (if the input is raw untrimmed fastq)"
 if [ ! -z "$proband_name" ] && [ "$trimming" = true ]; then
     echo "STEP 1a : Proband"
 
-    if [ -f ${FASTQ_DIR}/${proband_name}_1.fastq ] && [ -f ${FASTQ_DIR}/${proband_name}_2.fastq ]; then
+    if [ -f "${FASTQ_DIR}/${proband_name}_1.fastq" ] && [ -f "${FASTQ_DIR}/${proband_name}_2.fastq" ]; then
         echo "Raw fastq exist, continue to Trimming"
     else
         echo "File not exist, please check the input directory"
         exit 1
     fi
 
-    if [ -f ${FASTQ_DIR}/${proband_name}_1.fq.gz ] && [ -f ${FASTQ_DIR}/${proband_name}_2.fq.gz ]; then
+    if [ -f "${FASTQ_DIR}/${proband_name}_1.fq.gz" ] && [ -f "${FASTQ_DIR}/${proband_name}_2.fq.gz" ]; then
         echo "Output fq.qz exist, skipping Trimming"
     else
         echo "File not exist, continue to Trimming"
@@ -169,14 +169,14 @@ fi
 if [ ! -z "$mother_name" ] && [ "$trimming" = true ] && [ "$trio_analysis" = true ]; then
     echo "STEP 1b : Mother"
     
-    if [ -f ${FASTQ_DIR}/${mother_name}_1.fastq ] && [ -f ${FASTQ_DIR}/${mother_name}_2.fastq ]; then
+    if [ -f "${FASTQ_DIR}/${mother_name}_1.fastq" ] && [ -f "${FASTQ_DIR}/${mother_name}_2.fastq" ]; then
         echo "Raw fastq exist, continue to Trimming"
     else
         echo "File not exist, please check the input directory"
         exit 1
     fi
 
-    if [ -f ${FASTQ_DIR}/${mother_name}_1.fq.gz ] && [ -f ${FASTQ_DIR}/${mother_name}_2.fq.gz ]; then
+    if [ -f "${FASTQ_DIR}/${mother_name}_1.fq.gz" ] && [ -f "${FASTQ_DIR}/${mother_name}_2.fq.gz" ]; then
         echo "Output fq.qz exist, skipping Trimming"
     else
         echo "File not exist, continue to Trimming"
@@ -197,14 +197,14 @@ fi
 if [ ! -z "$father_name" ] && [ "$trimming" = true ] && [ "$trio_analysis" = true ]; then
     echo "STEP 1C : Father"
     
-    if [ -f ${FASTQ_DIR}/${father_name}_1.fastq ] && [ -f ${FASTQ_DIR}/${father_name}_2.fastq ]; then
+    if [ -f "${FASTQ_DIR}/${father_name}_1.fastq" ] && [ -f "${FASTQ_DIR}/${father_name}_2.fastq" ]; then
         echo "Raw fastq exist, continue to Trimming"
     else
         echo "File not exist, please check the input directory"
         exit 1
     fi
 
-    if [ -f ${FASTQ_DIR}/${father_name}_1.fq.gz ] && [ -f ${FASTQ_DIR}/${father_name}_2.fq.gz ]; then
+    if [ -f "${FASTQ_DIR}/${father_name}_1.fq.gz" ] && [ -f "${FASTQ_DIR}/${father_name}_2.fq.gz" ]; then
         echo "Output fq.qz exist, skipping Trimming"
     else
         echo "File not exist, continue to Trimming"
@@ -230,14 +230,14 @@ echo "STEP 2: Map to reference using BWA-MEM2"
 if [ ! -z "$proband_name" ]; then
     echo "STEP 2a : Proband"
 
-    if [ -f ${FASTQ_DIR}/${proband_name}_1.fq.gz ] && [ -f ${FASTQ_DIR}/${proband_name}_2.fq.gz ]; then
+    if [ -f "${FASTQ_DIR}/${proband_name}_1.fq.gz" ] && [ -f "${FASTQ_DIR}/${proband_name}_2.fq.gz" ]; then
         echo "Paired end fq.qz exist, continue to BWA-MEM2"
     else
         echo "File not exist, please check the input directory"
         exit 1
     fi
 
-    if [-f ${SAM_DIR}/${proband_name}_raw.sam ] || [ -f ${INPUT_DIR}/${proband_name}.bam ]; then
+    if [-f "${SAM_DIR}/${proband_name}_raw.sam" ] || [ -f "${INPUT_DIR}/${proband_name}.bam" ]; then
         echo "SAM file or final BAM file exist, skipping BWA-MEM2"
     else
         # BWA MEM2 Alignment
@@ -255,14 +255,14 @@ fi
 if [ ! -z "$mother_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 2b : Mother"
 
-    if [ -f ${FASTQ_DIR}/${mother_name}_1.fq.gz ] && [ -f ${FASTQ_DIR}/${mother_name}_2.fq.gz ]; then
+    if [ -f "${FASTQ_DIR}/${mother_name}_1.fq.gz" ] && [ -f "${FASTQ_DIR}/${mother_name}_2.fq.gz" ]; then
         echo "Paired end fq.qz exist, continue to BWA-MEM2"
     else
         echo "File not exist, please check the input directory"
         exit 1
     fi
     
-    if [-f ${SAM_DIR}/${mother_name}_raw.sam ] || [ -f ${INPUT_DIR}/${mother_name}.bam ]; then
+    if [-f "${SAM_DIR}/${mother_name}_raw.sam" ] || [ -f "${INPUT_DIR}/${mother_name}.bam" ]; then
         echo "SAM file or final BAM file exist, skipping BWA-MEM2"
     else
         # BWA MEM2 Alignment
@@ -280,14 +280,14 @@ fi
 if [ ! -z "$father_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 2c : Father"
     
-    if [ -f ${FASTQ_DIR}/${father_name}_1.fq.gz ] && [ -f ${FASTQ_DIR}/${father_name}_2.fq.gz ]; then
+    if [ -f "${FASTQ_DIR}/${father_name}_1.fq.gz" ] && [ -f "${FASTQ_DIR}/${father_name}_2.fq.gz" ]; then
         echo "Paired end fq.qz exist, continue to BWA-MEM2"
     else
         echo "File not exist, please check the input directory"
         exit 1
     fi
 
-    if [-f ${SAM_DIR}/${father_name}_raw.sam ] || [ -f ${INPUT_DIR}/${father_name}.bam ]; then
+    if [-f "${SAM_DIR}/${father_name}_raw.sam" ] || [ -f "${INPUT_DIR}/${father_name}.bam" ]; then
         echo "SAM file or final BAM file exist, skipping BWA-MEM2"
     else
         # BWA MEM2 Alignment
@@ -312,7 +312,7 @@ echo "STEP 3: Mark Duplicates and Sort - Sambamba"
 if [ ! -z "$proband_name" ]; then
     echo "STEP 3a : Proband"
 
-    if [ -f ${INPUT_DIR}/${proband_name}.bam ]; then
+    if [ -f "${INPUT_DIR}/${proband_name}.bam" ]; then
         echo "Final BAM file exist, skipping Mark Duplicates and Sort"
     else
         sambamba view -p -t=$(nproc) -l=9 \
@@ -333,7 +333,7 @@ fi
 if [ ! -z "$mother_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 3b : Mother"
 
-    if [ -f ${INPUT_DIR}/${mother_name}.bam ]; then
+    if [ -f "${INPUT_DIR}/${mother_name}.bam" ]; then
         echo "Final BAM file exist, skipping Mark Duplicates and Sort"
     else
         sambamba view -p -t=$(nproc) -l=9 \
@@ -354,7 +354,7 @@ fi
 if [ ! -z "$father_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 3c : Father"
     
-    if [ -f ${INPUT_DIR}/${father_name}.bam ]; then
+    if [ -f "${INPUT_DIR}/${father_name}.bam" ]; then
         echo "Final BAM file exist, skipping Mark Duplicates and Sort"
     else
         sambamba view -p -t=$(nproc) -l=9 \
@@ -373,13 +373,13 @@ fi
 
 ### Remove Intermediate SAM BAM file as it consumes too much spaces
 
-#### Remove all in one folder 
-rm ${SAM_DIR}/*.sam ${SAM_DIR}/*.bam
-
-#### Remove one by one
-rm ${SAM_DIR}/${proband_name}_raw.sam ${SAM_DIR}/${mother_name}_raw.sam ${SAM_DIR}/${father_name}_raw.sam
-rm ${SAM_DIR}/${proband_name}_raw.bam ${SAM_DIR}/${mother_name}_raw.bam ${SAM_DIR}/${father_name}_raw.bam
-rm ${SAM_DIR}/${proband_name}_dedup.bam ${SAM_DIR}/${mother_name}_dedup.bam ${SAM_DIR}/${father_name}_dedup.bam
+# Check if the directory exists
+if [ -d "$SAM_DIR" ]; then
+    echo "Remove all data inside SAM directory to save harddisk space"
+    rm -r "$SAM_DIR"
+else
+    echo "Directory $SAM_DIR does not exist."
+fi
 
 # ----------------------------------------------
 # STEP 4: Variant Calling
@@ -389,8 +389,8 @@ if [ ! -z "$proband_name" ] && [ "$solo_analysis" = true ]; then
     echo "STEP 4a: Variant Calling Proband DeepVariant"
 
     # Further check if ${INPUT_DIR}/${proband_name}.bam all exists
-    if [ -f ${INPUT_DIR}/${proband_name}.bam ]; then
-        if [ -f ${OUTPUT_DIR}/${proband_name}_proband.vcf.gz]; then
+    if [ -f "${INPUT_DIR}/${proband_name}.bam" ]; then
+        if [ -f "${OUTPUT_DIR}/${proband_name}_proband.vcf.gz" ]; then
             echo "VCF file exist, skipping DeepVariant"
         else
             echo "BAM file exist, continue to DeepVariant"
@@ -425,9 +425,9 @@ if [ ! -z "$proband_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 4b: Variant Calling DeepTrio"
 
     # Further check if ${INPUT_DIR}/${father_name}.bam and ${INPUT_DIR}/${mother_name}.bam and ${INPUT_DIR}/${proband_name}.bam all exists
-    if [ -f ${INPUT_DIR}/${father_name}.bam ] && [ -f ${INPUT_DIR}/${mother_name}.bam ] && [ -f ${INPUT_DIR}/${proband_name}.bam ]; then
+    if [ -f "${INPUT_DIR}/${father_name}.bam" ] && [ -f "${INPUT_DIR}/${mother_name}.bam" ] && [ -f "${INPUT_DIR}/${proband_name}.bam" ]; then
 
-        if [ -f ${OUTPUT_DIR}/${proband_name}.g.vcf.gz] && [ -f ${OUTPUT_DIR}/${father_name}.g.vcf.gz] && [ -f ${OUTPUT_DIR}/${mother_name}.g.vcf.gz]; then
+        if [ -f "${OUTPUT_DIR}/${proband_name}.g.vcf.gz" ] && [ -f "${OUTPUT_DIR}/${father_name}.g.vcf.gz" ] && [ -f "${OUTPUT_DIR}/${mother_name}.g.vcf.gz" ]; then
             echo "gVCF file exist, skipping DeepTrio"
         else
             echo "All BAM files exist, continue to DeepTrio"
@@ -474,7 +474,7 @@ fi
 if [ ! -z "$proband_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 5: Merge gVCF files with GLnexus"
 
-    if [ -f ${OUTPUT_DIR}/${proband_name}_trio_merged.vcf.gz ]; then
+    if [ -f "${OUTPUT_DIR}/${proband_name}_trio_merged.vcf.gz" ]; then
         echo "Merged VCF file exist, skipping GLnexus"
     else
         docker run \
@@ -498,22 +498,22 @@ if [ ! -z "$proband_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 6: Calculate Mendelian Violation Rate using RTG Tools"
     #### Reference : https://www.animalgenome.org/bioinfo/resources/manuals/RTGOperationsManual.pdf
 
-    if [ -d ${REFERENCE_DIR}/${REFSEQ_FASTA}.sdf ];
-    then
-        echo "${REFERENCE_DIR}/${REFSEQ_FASTA}.sdf exists. Removing directory."
-        rm -r -f ${REFERENCE_DIR}/${REFSEQ_FASTA}.sdf
-    else
-        echo "${REFERENCE_DIR}/${REFSEQ_FASTA}.sdf directory does not exist. Continue"
-    fi
 
-    if [ -f ${OUTPUT_DIR}/${proband_name}_trio_merged.vcf.gz ]; then
+    if [ -f "${OUTPUT_DIR}/${proband_name}_trio_merged.vcf.gz" ]; then
         echo "Merged VCF file exist, continue to RTG Tools"
 
-        docker run \
-            -v "${INPUT_DIR}":"/input" \
-            -v "${REFERENCE_DIR}":"/reference" \
-            realtimegenomics/rtg-tools format \
-            -o /reference/${REFSEQ_FASTA}.sdf "/reference/${REFSEQ_FASTA}"
+        if [ -d ${REFERENCE_DIR}/${REFSEQ_FASTA}.sdf ];
+        then
+            echo "${REFERENCE_DIR}/${REFSEQ_FASTA}.sdf exists. Didn't create sdf."
+        else
+            echo "${REFERENCE_DIR}/${REFSEQ_FASTA}.sdf directory does not exist. Creating it"
+            docker run \
+                -v "${INPUT_DIR}":"/input" \
+                -v "${REFERENCE_DIR}":"/reference" \
+                realtimegenomics/rtg-tools format \
+                -o /reference/${REFSEQ_FASTA}.sdf "/reference/${REFSEQ_FASTA}"
+        fi
+
 
         docker run \
             -v "${INPUT_DIR}":"/input" \
@@ -543,9 +543,9 @@ if [ ! -z "$proband_name" ] && [ "$trio_analysis" = true ]; then
         echo "Merged VCF file not exist, please check the input directory"
         exit 1
     fi
-    
+fi
 
-elif [ ! -z "$proband_name" ] && [ "$solo_analysis" = true ]; then
+if [ ! -z "$proband_name" ] && [ "$solo_analysis" = true ]; then
     echo "SKIPPED STEP 5: Merge gVCF files with GLnexus, due to solo analysis (Trio)"
     echo "SKIPPED STEP 6: Calculate Mendelian Violation Rate using RTG Tools (Trio)"
 fi
@@ -559,82 +559,82 @@ fi
 if [ ! -z "$proband_name" ] && [ "$solo_analysis" = true ]; then
     echo "STEP 7a: Annotate Variants Proband - SNPEff with latest database, SnpSift ClinVar, SnpSift dbNSFP"
     
-    if [ ! -f ${OUTPUT_DIR}/${proband_name}_proband.vcf.gz] :
+    if [ ! -f "${OUTPUT_DIR}/${proband_name}_proband.vcf.gz" ]; then
         echo "VCF file not exist, please check the input directory"
         exit 1
     fi
 
     # If output file not exist, run annotate
-    if [ ! -f ${proband_name}-converted-deepVariant.vcf] && [ ! -f ${proband_name}-converted-deepVariant.vcf.gz]:
+    if [ ! -f "${proband_name}-converted-deepVariant.vcf" ] && [ ! -f "${proband_name}-converted-deepVariant.vcf.gz" ]; then
         # Create GATK > dbnsfp Chromosome
         bcftools annotate \
-            --rename-chrs ${chr_rename} \
-            --threads nproc -Oz \
-            -o ${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf \
-            ${OUTPUT_DIR}/${proband_name}_proband.vcf.gz
+            --rename-chrs "${chr_rename}" \
+            --threads "$(nproc)" -Oz \
+            -o "${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf" \
+            "${OUTPUT_DIR}/${proband_name}_proband.vcf.gz"
     else
-        echo "Deepvariant converted VCF file exist, skipping conversion"
+        echo "Deepvariant converted VCF file exists, skipping conversion"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf.gz] && [ -f ${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf] :
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf.gz" ] && [ -f "${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf" ]; then
         # SnpEff with recent GRCh38.p14 database
-        SnpEff -v ${snpEff_ver} -dataDir ${snpEff_dir} \
-            -s ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.html \
-            ${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf
+        SnpEff -v "${snpEff_ver}" -dataDir "${snpEff_dir}" \
+            -s "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.html" \
+            "${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf"
     else
-        echo "SnpEff VCF file exist, skipping SnpEff"
+        echo "SnpEff VCF file exists, skipping SnpEff"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf.gz] && [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf] :
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf.gz" ] && [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf" ]; then
         # SnpSift Annotate ClinVar
-        SnpSift annotate -v ${dbSNP} \
-            ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf
+        SnpSift annotate -v "${dbSNP}" \
+            "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf"
     else
-        echo "Annotated dbSNP file exist, skipping annotation"
+        echo "Annotated dbSNP file exists, skipping annotation"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf.gz] && [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf] :
-        SnpSift annotate -v ${ClinVar} \
-            ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf.gz" ] && [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf" ]; then
+        SnpSift annotate -v "${ClinVar}" \
+            "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf"
     else
-        echo "Annotated ClinVar file exist, skipping annotation"
+        echo "Annotated ClinVar file exists, skipping annotation"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf.gz] && [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf] :
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf.gz" ] && [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf" ]; then
         # Annotate using dbNSFP for SNP Only (Indel Give 0 Annotation Result)
-        SnpSift dbnsfp -v -db ${dbnsfp} \
-            ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf
+        SnpSift dbnsfp -v -db "${dbnsfp}" \
+            "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf"
     else
-        echo "Annotated dbNSFP file exist, skipping annotation"
+        echo "Annotated dbNSFP file exists, skipping annotation"
     fi
 
     # Compress file size using bgzip if the previous .vcf file exist
-    if [ -f ${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf] && [ ! -f ${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf.gz]: 
-        bgzip --threads nproc ${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf
+    if [ -f "${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf" ] && [ ! -f "${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${OUTPUT_DIR}/${proband_name}-converted-deepVariant.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepVariant.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepVariant.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepVariant.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf"
     fi
 fi
 
@@ -644,86 +644,87 @@ if [ ! -z "$proband_name" ] && [ "$trio_analysis" = true ]; then
     echo "STEP 7b: Annotate Variants Trio - SNP Sift"
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf] && [ ! -f ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf.gz]:
+    if [ ! -f "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf" ] && [ ! -f "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf.gz" ]; then
         # Create GATK > dbnsfp Chromosome
         bcftools annotate \
-            --rename-chrs ${chr_rename} \
-            --threads nproc -Oz \
-            -o ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf \
-            ${OUTPUT_DIR}/${proband_name}_trio_annotated.output.vcf.gz
+            --rename-chrs "${chr_rename}" \
+            --threads "$(nproc)" -Oz \
+            -o "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf" \
+            "${OUTPUT_DIR}/${proband_name}_trio_annotated.output.vcf.gz"
     else
-        echo "DeepTrio converted VCF file exist, skipping conversion"
+        echo "DeepTrio converted VCF file exists, skipping conversion"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf.gz] && [ -f ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf] :
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf.gz" ] && [ -f "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf" ]; then
         # SnpEff with recent GRCh38.p14 database
-        SnpEff -v ${snpEff_ver} -dataDir ${snpEff_dir} \
-            -s ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.html \
-            ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf
+        SnpEff -v "${snpEff_ver}" -dataDir "${snpEff_dir}" \
+            -s "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.html" \
+            "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf"
     else
-        echo "SnpEff VCF file exist, skipping SnpEff"
+        echo "SnpEff VCF file exists, skipping SnpEff"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf.gz] && [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf] :
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf.gz" ] && [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf" ]; then
         # SnpSift
-        SnpSift annotate -v ${dbSNP} \
-            ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf
+        SnpSift annotate -v "${dbSNP}" \
+            "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf"
     else
-        echo "Annotated dbSNP file exist, skipping annotation"
+        echo "Annotated dbSNP file exists, skipping annotation"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf.gz] && [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf] :
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf.gz" ] && [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf" ]; then
         # SnpSift Annotate ClinVar
-        SnpSift annotate -v ${ClinVar} \
-            ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf
+        SnpSift annotate -v "${ClinVar}" \
+            "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf"
     else
-        echo "Annotated ClinVar file exist, skipping annotation"
+        echo "Annotated ClinVar file exists, skipping annotation"
     fi
 
     # If output file not exist yet, and previous file exist
-    if [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf.gz] && [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf] :
+    if [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf.gz" ] && [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf" ]; then
         # Annotate using dbNSFP for SNP Only (Indel Give 0 Annotation Result)
-        SnpSift dbnsfp -v -db ${dbnsfp} \
-            ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf \
-            > ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf
+        SnpSift dbnsfp -v -db "${dbnsfp}" \
+            "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf" \
+            > "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf"
     else
-        echo "Annotated dbNSFP file exist, skipping annotation"
+        echo "Annotated dbNSFP file exists, skipping annotation"
     fi
 
     # Compress file size using bgzip if the previous .vcf file exist
-    if [ -f ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf] && [ ! -f ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf.gz]: 
-        bgzip --threads nproc ${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf
+    if [ -f "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf" ] && [ ! -f "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${OUTPUT_DIR}/${proband_name}-converted-deepTrio.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-deepTrio.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-deepTrio.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-deepTrio.vcf"
     fi
 
-    if [ -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf] && [ ! -f ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf.gz]: 
-        bgzip --threads nproc ${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf
+    if [ -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf" ] && [ ! -f "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf.gz" ]; then
+        bgzip --threads "$(nproc)" "${ANNOTATED_DIR}/${proband_name}-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf"
     fi
+fi
 
 # Additional SV Step using Tiddit @ SV_DIR
 
-# Check if proband_name is not null
-if [ ! -z "$proband_name" ]; then
+# Check if proband_name is not null and annotated tiddit output is not yet exist in folder
+if [ ! -z "$proband_name" ] && [ ! -f "${SV_DIR}/output.filtered.dbnsfp.vcf" ]; then
     echo "STEP 8: SV calling using Tiddit, SnpEff annotation, SnpSift dbNSFP annotation"
 
-    if [ -f ${INPUT_DIR}/${proband_name}.bam ]; then
+    if [ -f "${INPUT_DIR}/${proband_name}.bam" ]; then
         echo "Final BAM file exist, continue to Tiddit"
         docker run \
             -v "${INPUT_DIR}":"/input"   \
@@ -752,6 +753,8 @@ if [ ! -z "$proband_name" ]; then
         echo "BAM file not exist, please check the input directory"
         exit 1
     fi
+else
+    echo "SV output folder exist, and there are already final data, skipping Tiddit"  
 fi
 
 # Step using Exomiser @ Exomiser root folder
@@ -764,12 +767,12 @@ fi
 
 # Check if trio_analysis is true
 if [ "$trio_analysis" = true ]; then
-    echo "STEP 9: Exomiser SNP Solo Trio Analysis"
+    echo "STEP 9: Exomiser SNP Trio Analysis"
     exomiser --analysis ${exomiser_trio}
 fi
 
 # Check if SV VCF is true
-if [ -f ${SV_DIR}/output.filtered.dbnsfp.vcf ]; then
-    echo "STEP 9: Exomiser SV Solo Trio Analysis"
+if [ -f "${SV_DIR}/output.filtered.dbnsfp.vcf" ]; then
+    echo "STEP 9: Exomiser SV Solo Analysis"
     exomiser --analysis ${exomiser_solo_sv}
 fi
\ No newline at end of file
diff --git a/example/exomiser_html_clinical_report/V350145665_L04_B5EHOMdmhwXAAAA-515-exomiser-solo.html b/example/exomiser_html_clinical_report/V350145665_L04_B5EHOMdmhwXAAAA-515-exomiser-solo.html
new file mode 100644
index 0000000..d4ba26c
--- /dev/null
+++ b/example/exomiser_html_clinical_report/V350145665_L04_B5EHOMdmhwXAAAA-515-exomiser-solo.html
@@ -0,0 +1,9871 @@
+<!--
+  ~ The Exomiser - A tool to annotate and prioritize genomic variants
+  ~
+  ~ Copyright (c) 2016-2021 Queen Mary University of London.
+  ~ Copyright (c) 2012-2016 Charité Universitätsmedizin Berlin and Genome Research Ltd.
+  ~
+  ~ This program is free software: you can redistribute it and/or modify
+  ~ it under the terms of the GNU Affero General Public License as
+  ~ published by the Free Software Foundation, either version 3 of the
+  ~ License, or (at your option) any later version.
+  ~
+  ~ This program is distributed in the hope that it will be useful,
+  ~ but WITHOUT ANY WARRANTY; without even the implied warranty of
+  ~ MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
+  ~ GNU Affero General Public License for more details.
+  ~
+  ~ You should have received a copy of the GNU Affero General Public License
+  ~ along with this program.  If not, see <http://www.gnu.org/licenses/>.
+  -->
+
+<!DOCTYPE html>
+
+<html xmlns="http://www.w3.org/1999/xhtml">
+
+<head>
+    <title>The Exomiser - A Tool to Annotate and Prioritise Whole-Exome Sequencing Data</title>
+    <meta charset="UTF-8"/>
+    <meta name="viewport" content="width=device-width, initial-scale=1.0"/>
+    <style>
+        /*!
+ * Bootstrap v3.3.7 (http://getbootstrap.com)
+ * Copyright 2011-2016 Twitter, Inc.
+ * Licensed under MIT (https://github.com/twbs/bootstrap/blob/master/LICENSE)
+ *//*! normalize.css v3.0.3 | MIT License | github.com/necolas/normalize.css */html{font-family:sans-serif;-webkit-text-size-adjust:100%;-ms-text-size-adjust:100%}body{margin:0}article,aside,details,figcaption,figure,footer,header,hgroup,main,menu,nav,section,summary{display:block}audio,canvas,progress,video{display:inline-block;vertical-align:baseline}audio:not([controls]){display:none;height:0}[hidden],template{display:none}a{background-color:transparent}a:active,a:hover{outline:0}abbr[title]{border-bottom:1px dotted}b,strong{font-weight:700}dfn{font-style:italic}h1{margin:.67em 0;font-size:2em}mark{color:#000;background:#ff0}small{font-size:80%}sub,sup{position:relative;font-size:75%;line-height:0;vertical-align:baseline}sup{top:-.5em}sub{bottom:-.25em}img{border:0}svg:not(:root){overflow:hidden}figure{margin:1em 40px}hr{height:0;-webkit-box-sizing:content-box;-moz-box-sizing:content-box;box-sizing:content-box}pre{overflow:auto}code,kbd,pre,samp{font-family:monospace,monospace;font-size:1em}button,input,optgroup,select,textarea{margin:0;font:inherit;color:inherit}button{overflow:visible}button,select{text-transform:none}button,html input[type=button],input[type=reset],input[type=submit]{-webkit-appearance:button;cursor:pointer}button[disabled],html input[disabled]{cursor:default}button::-moz-focus-inner,input::-moz-focus-inner{padding:0;border:0}input{line-height:normal}input[type=checkbox],input[type=radio]{-webkit-box-sizing:border-box;-moz-box-sizing:border-box;box-sizing:border-box;padding:0}input[type=number]::-webkit-inner-spin-button,input[type=number]::-webkit-outer-spin-button{height:auto}input[type=search]{-webkit-box-sizing:content-box;-moz-box-sizing:content-box;box-sizing:content-box;-webkit-appearance:textfield}input[type=search]::-webkit-search-cancel-button,input[type=search]::-webkit-search-decoration{-webkit-appearance:none}fieldset{padding:.35em .625em .75em;margin:0 2px;border:1px solid silver}legend{padding:0;border:0}textarea{overflow:auto}optgroup{font-weight:700}table{border-spacing:0;border-collapse:collapse}td,th{padding:0}/*! Source: https://github.com/h5bp/html5-boilerplate/blob/master/src/css/main.css */@media print{*,:after,:before{color:#000!important;text-shadow:none!important;background:0 0!important;-webkit-box-shadow:none!important;box-shadow:none!important}a,a:visited{text-decoration:underline}a[href]:after{content:" (" attr(href) ")"}abbr[title]:after{content:" (" attr(title) ")"}a[href^="javascript:"]:after,a[href^="#"]:after{content:""}blockquote,pre{border:1px solid #999;page-break-inside:avoid}thead{display:table-header-group}img,tr{page-break-inside:avoid}img{max-width:100%!important}h2,h3,p{orphans:3;widows:3}h2,h3{page-break-after:avoid}.navbar{display:none}.btn>.caret,.dropup>.btn>.caret{border-top-color:#000!important}.label{border:1px solid #000}.table{border-collapse:collapse!important}.table td,.table th{background-color:#fff!important}.table-bordered td,.table-bordered th{border:1px solid #ddd!important}}@font-face{font-family:'Glyphicons 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print{.visible-print{display:block!important}table.visible-print{display:table!important}tr.visible-print{display:table-row!important}td.visible-print,th.visible-print{display:table-cell!important}}.visible-print-block{display:none!important}@media print{.visible-print-block{display:block!important}}.visible-print-inline{display:none!important}@media print{.visible-print-inline{display:inline!important}}.visible-print-inline-block{display:none!important}@media print{.visible-print-inline-block{display:inline-block!important}}@media print{.hidden-print{display:none!important}}
+        /*# sourceMappingURL=bootstrap.min.css.map */
+    </style>
+    <!--<link rel="stylesheet" type="text/css" media="all" href="../../resources/bootstrap-3.2.0/css/bootstrap.min.css" th:href="@{resources/bootstrap-3.2.0/css/bootstrap.min.css}"/>-->
+</head>
+<body>
+<div id="content" class="container">
+    <h2>
+        Exomiser Analysis Results for
+        Anonymous
+    </h2>
+    <ul class="nav nav-pills" id="tabs">
+        <li><a href="#settings" role="tab" data-toggle="tab"><b>Analysis Settings</b></a></li>
+        <li><a href="#filtering" role="tab" data-toggle="tab"><b>Filtering Summary</b></a></li>
+        <li><a href="#distribution" role="tab" data-toggle="tab"><b>Variant Type Distribution</b></a></li>
+        <li><a href="#prioritisation" role="tab" data-toggle="tab"><b>Prioritised Genes</b></a></li>
+        
+        <li><a href="#about" role="tab" data-toggle="tab"><b>About</b></a></li>
+    </ul>
+    <div class="panel panel-default" id="settings">
+        <div class="panel-heading">
+            <h3>Analysis Settings</h3>
+        </div>
+        <div class="panel-body"><p>Settings used for this analysis:</p>
+            <pre>---
+sample:
+  genomeAssembly: &quot;hg38&quot;
+  vcf: &quot;/home/ivanwilliamharsono/Downloads/trio_patient/annotated/V350145665_L04_B5EHOMdmhwXAAAA-515-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepVariant.vcf.gz&quot;
+  hpoIds:
+  - &quot;HP:0000007&quot;
+  - &quot;HP:0001433&quot;
+  - &quot;HP:0001903&quot;
+  - &quot;HP:0001541&quot;
+  - &quot;HP:0010972&quot;
+  - &quot;HP:0005561&quot;
+  - &quot;HP:0001396&quot;
+  - &quot;HP:0001410&quot;
+  - &quot;HP:0002910&quot;
+  - &quot;HP:0001399&quot;
+  - &quot;HP:0000938&quot;
+  - &quot;HP:0001642&quot;
+  - &quot;HP:0200114&quot;
+  - &quot;HP:0003073&quot;
+  - &quot;HP:0003233&quot;
+  - &quot;HP:0001873&quot;
+  - &quot;HP:0002151&quot;
+  - &quot;HP:0031964&quot;
+  - &quot;HP:0031956&quot;
+  - &quot;HP:0002366&quot;
+  - &quot;HP:0006568&quot;
+  - &quot;HP:0004333&quot;
+  - &quot;HP:0001531&quot;
+  pedigree: {}
+  age: {}
+analysis:
+  inheritanceModes:
+    AUTOSOMAL_RECESSIVE_COMP_HET: 2.0
+    MITOCHONDRIAL: 0.2
+    AUTOSOMAL_RECESSIVE_HOM_ALT: 0.1
+    X_DOMINANT: 0.1
+    AUTOSOMAL_DOMINANT: 0.1
+    X_RECESSIVE_COMP_HET: 2.0
+    X_RECESSIVE_HOM_ALT: 0.1
+  frequencySources:
+  - &quot;THOUSAND_GENOMES&quot;
+  - &quot;TOPMED&quot;
+  - &quot;UK10K&quot;
+  - &quot;ESP_AFRICAN_AMERICAN&quot;
+  - &quot;ESP_EUROPEAN_AMERICAN&quot;
+  - &quot;ESP_ALL&quot;
+  - &quot;EXAC_AFRICAN_INC_AFRICAN_AMERICAN&quot;
+  - &quot;EXAC_AMERICAN&quot;
+  - &quot;EXAC_EAST_ASIAN&quot;
+  - &quot;EXAC_FINNISH&quot;
+  - &quot;EXAC_NON_FINNISH_EUROPEAN&quot;
+  - &quot;EXAC_OTHER&quot;
+  - &quot;EXAC_SOUTH_ASIAN&quot;
+  - &quot;GNOMAD_E_AFR&quot;
+  - &quot;GNOMAD_E_AMR&quot;
+  - &quot;GNOMAD_E_EAS&quot;
+  - &quot;GNOMAD_E_FIN&quot;
+  - &quot;GNOMAD_E_NFE&quot;
+  - &quot;GNOMAD_E_OTH&quot;
+  - &quot;GNOMAD_E_SAS&quot;
+  - &quot;GNOMAD_G_AFR&quot;
+  - &quot;GNOMAD_G_AMR&quot;
+  - &quot;GNOMAD_G_EAS&quot;
+  - &quot;GNOMAD_G_FIN&quot;
+  - &quot;GNOMAD_G_NFE&quot;
+  - &quot;GNOMAD_G_OTH&quot;
+  - &quot;GNOMAD_G_SAS&quot;
+  pathogenicitySources:
+  - &quot;REVEL&quot;
+  - &quot;MVP&quot;
+  steps:
+  - failedVariantFilter: {}
+  - variantEffectFilter:
+      remove:
+      - &quot;CODING_TRANSCRIPT_INTRON_VARIANT&quot;
+      - &quot;FIVE_PRIME_UTR_EXON_VARIANT&quot;
+      - &quot;THREE_PRIME_UTR_EXON_VARIANT&quot;
+      - &quot;FIVE_PRIME_UTR_INTRON_VARIANT&quot;
+      - &quot;THREE_PRIME_UTR_INTRON_VARIANT&quot;
+      - &quot;NON_CODING_TRANSCRIPT_EXON_VARIANT&quot;
+      - &quot;NON_CODING_TRANSCRIPT_INTRON_VARIANT&quot;
+      - &quot;UPSTREAM_GENE_VARIANT&quot;
+      - &quot;DOWNSTREAM_GENE_VARIANT&quot;
+      - &quot;INTERGENIC_VARIANT&quot;
+      - &quot;REGULATORY_REGION_VARIANT&quot;
+  - frequencyFilter:
+      maxFrequency: 2.0
+  - pathogenicityFilter:
+      keepNonPathogenic: true
+  - inheritanceFilter: {}
+  - omimPrioritiser: {}
+  - hiPhivePrioritiser:
+      runParams: &quot;human, mouse, fish, ppi&quot;
+  - phenixPrioritiser: {}
+outputOptions:
+  outputContributingVariantsOnly: true
+  numGenes: 50
+  outputFormats:
+  - &quot;HTML&quot;
+  - &quot;VCF&quot;
+  - &quot;TSV_GENE&quot;
+  - &quot;TSV_VARIANT&quot;
+  - &quot;JSON&quot;
+  outputFileName: &quot;V350145665_L04_B5EHOMdmhwXAAAA-515-exomiser-solo&quot;
+  outputDirectory: &quot;/home/ivanwilliamharsono/Downloads/trio_patient/exomiser&quot;
+</pre>
+        </div>
+    </div>
+
+    <div class="panel panel-default" id="filtering">
+        <div class="panel-heading">
+            <h3>Filtering Summary</h3>
+        </div>
+        <div class="panel-body">
+            <table class="table">
+                <thead>
+                <tr>
+                    <th>Filter</th>
+                    <th>Report</th>
+                    <th>Passed filter</th>
+                    <th>Failed filter</th>
+                </tr>
+                </thead>
+                <tbody>
+                <tr>
+                    <td><b>Failed previous VCF filters</b></td>
+                    <td>
+                        
+                    </td>
+                    <td>648</td>
+                    <td>0</td>
+                </tr>
+                <tr>
+                    <td><b>Variant effect</b></td>
+                    <td>
+                        <ul>Removed variants with effects of type: [CODING_TRANSCRIPT_INTRON_VARIANT, FIVE_PRIME_UTR_EXON_VARIANT, THREE_PRIME_UTR_EXON_VARIANT, FIVE_PRIME_UTR_INTRON_VARIANT, THREE_PRIME_UTR_INTRON_VARIANT, NON_CODING_TRANSCRIPT_EXON_VARIANT, NON_CODING_TRANSCRIPT_INTRON_VARIANT, UPSTREAM_GENE_VARIANT, DOWNSTREAM_GENE_VARIANT, INTERGENIC_VARIANT, REGULATORY_REGION_VARIANT]</ul>
+                    </td>
+                    <td>648</td>
+                    <td>0</td>
+                </tr>
+                <tr>
+                    <td><b>Frequency</b></td>
+                    <td>
+                        <ul>Variants filtered for maximum allele frequency of 2.00%</ul>
+                    </td>
+                    <td>648</td>
+                    <td>0</td>
+                </tr>
+                <tr>
+                    <td><b>Pathogenicity</b></td>
+                    <td>
+                        <ul>Retained all non-pathogenic variants of all types. Scoring was applied, but the filter passed all variants.</ul>
+                    </td>
+                    <td>648</td>
+                    <td>0</td>
+                </tr>
+                <tr>
+                    <td><b>Inheritance</b></td>
+                    <td>
+                        <ul>Genes filtered for compatibility with AUTOSOMAL_DOMINANT, AUTOSOMAL_RECESSIVE, X_RECESSIVE, X_DOMINANT, MITOCHONDRIAL inheritance.</ul>
+                    </td>
+                    <td>500</td>
+                    <td>0</td>
+                </tr>
+                </tbody>
+            </table>
+        </div>
+    </div>
+    <div class="panel panel-default" id="distribution">
+        <div class="panel-heading">
+            <h3>Variant Type Distribution</h3>
+        </div>
+        <div class="panel-body">
+            <table class="table-striped table-condensed">
+                <thead>
+                <tr>
+                    <th>Variant Type</th>
+                    
+                        <th>Proband</th>
+                    
+                </tr>
+                </thead>
+                <tbody>
+                <tr>
+                    <td>FRAMESHIFT_ELONGATION</td>
+                    
+                        <td>4</td>
+                    
+                </tr>
+                <tr>
+                    <td>FRAMESHIFT_TRUNCATION</td>
+                    
+                        <td>3</td>
+                    
+                </tr>
+                <tr>
+                    <td>FRAMESHIFT_VARIANT</td>
+                    
+                        <td>2</td>
+                    
+                </tr>
+                <tr>
+                    <td>INTERNAL_FEATURE_ELONGATION</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>FEATURE_TRUNCATION</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>MNV</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>STOP_GAINED</td>
+                    
+                        <td>6</td>
+                    
+                </tr>
+                <tr>
+                    <td>STOP_LOST</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>START_LOST</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>SPLICE_ACCEPTOR_VARIANT</td>
+                    
+                        <td>1</td>
+                    
+                </tr>
+                <tr>
+                    <td>SPLICE_DONOR_VARIANT</td>
+                    
+                        <td>1</td>
+                    
+                </tr>
+                <tr>
+                    <td>MISSENSE_VARIANT</td>
+                    
+                        <td>352</td>
+                    
+                </tr>
+                <tr>
+                    <td>INFRAME_INSERTION</td>
+                    
+                        <td>2</td>
+                    
+                </tr>
+                <tr>
+                    <td>DISRUPTIVE_INFRAME_INSERTION</td>
+                    
+                        <td>9</td>
+                    
+                </tr>
+                <tr>
+                    <td>INFRAME_DELETION</td>
+                    
+                        <td>1</td>
+                    
+                </tr>
+                <tr>
+                    <td>DISRUPTIVE_INFRAME_DELETION</td>
+                    
+                        <td>12</td>
+                    
+                </tr>
+                <tr>
+                    <td>FIVE_PRIME_UTR_TRUNCATION</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>THREE_PRIME_UTR_TRUNCATION</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>SPLICE_REGION_VARIANT</td>
+                    
+                        <td>49</td>
+                    
+                </tr>
+                <tr>
+                    <td>STOP_RETAINED_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>INITIATOR_CODON_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>SYNONYMOUS_VARIANT</td>
+                    
+                        <td>206</td>
+                    
+                </tr>
+                <tr>
+                    <td>CODING_TRANSCRIPT_INTRON_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>FIVE_PRIME_UTR_EXON_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>THREE_PRIME_UTR_EXON_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>FIVE_PRIME_UTR_INTRON_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>THREE_PRIME_UTR_INTRON_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>NON_CODING_TRANSCRIPT_EXON_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>NON_CODING_TRANSCRIPT_INTRON_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>UPSTREAM_GENE_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>DOWNSTREAM_GENE_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>INTERGENIC_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>REGULATORY_REGION_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                </tbody>
+            </table>
+        </div>
+    </div>
+
+    
+
+    <div class="panel panel-default" id="prioritisation">
+        <div class="panel-heading">
+            <h3>Prioritised Genes</h3>
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="GBE1" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000114480">GBE1</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.931</b>
+                    <data>(p=8.4E-4)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.658</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.985</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.639 to <a href="http://www.omim.org/entry/232500">Glycogen storage disease IV</a> associated with GBE1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0001903, Anemia - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0001541, Ascites - HP:0001541, Ascites</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0001396, Cholestasis - HP:0001399, Hepatic failure</dd><dd>HP:0001410, Decreased liver function - HP:0001399, Hepatic failure</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0001399, Hepatic failure</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001638, Cardiomyopathy</dd><dd>HP:0200114, Metabolic alkalosis - HP:0000969, Edema</dd><dd>HP:0003073, Hypoalbuminemia - HP:0040081, Abnormal circulating creatine kinase concentration</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0040081, Abnormal circulating creatine kinase concentration</dd><dd>HP:0001873, Thrombocytopenia - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0002151, Increased serum lactate - HP:0040081, Abnormal circulating creatine kinase concentration</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001394, Cirrhosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001508, Failure to thrive</dd></dl><dl><dt>Phenotypic similarity 0.658 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=GBE1">GBE1</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0003333, liver fibrosis</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0003333, liver fibrosis</dd><dd>HP:0001410, Decreased liver function - MP:0003333, liver fibrosis</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0003333, liver fibrosis</dd><dd>HP:0001399, Hepatic failure - MP:0003333, liver fibrosis</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - MP:0010090, increased circulating creatine kinase level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0010090, increased circulating creatine kinase level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0003333, liver fibrosis</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0003333, liver fibrosis</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0014074, increased brain glycogen level</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0010400, increased liver glycogen level</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.508 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=GBE1%0DPPP1R3C&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to PPP1R3C</a> and phenotypic similarity 0.604 to mouse mutant of PPP1R3C.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0010398, decreased liver glycogen level</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0010398, decreased liver glycogen level</dd><dd>HP:0001410, Decreased liver function - MP:0010398, decreased liver glycogen level</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0010398, decreased liver glycogen level</dd><dd>HP:0001399, Hepatic failure - MP:0010398, decreased liver glycogen level</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0002833, increased heart weight</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005669, increased circulating leptin level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0005669, increased circulating leptin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0001552, increased circulating triglyceride level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0005669, increased circulating leptin level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0010398, decreased liver glycogen level</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0010398, decreased liver glycogen level</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0010398, decreased liver glycogen level</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 1.57 (p-value: 0.000060)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/232500">OMIM:232500</a> Glycogen storage disease IV - autosomal recessive</dd>
+<dd><a href="http://www.omim.org/entry/263570">OMIM:263570</a> Polyglucosan body disease, adult form - autosomal recessive</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=206583">ORPHA:206583</a> Adult polyglucosan body disease - autosomal recessive</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.931</b>
+                                    <data>(p=8.4E-4)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.658</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.985</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.639 to OMIM:232500 Glycogen storage disease IV</dt>
+                                
+                                    <dt>Phenotypic similarity 0.475 to OMIM:263570 Polyglucosan body disease, adult form</dt>
+                                
+                                    <dt>Phenotypic similarity 0.203 to ORPHA:206583 Adult polyglucosan body disease</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>3-81648954-C-G [1/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting, PP3_Moderate, PP4]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.985</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000429644.7">GBE1:ENST00000429644.7:c.593G&gt;C:p.(Arg198Thr)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.9849782</dd>
+                                    
+                                    <dd>REVEL: 0.873</dd>
+                                    <dd>MVP: 0.985</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="ABCG5" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000138075">ABCG5</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.914</b>
+                    <data>(p=1.4E-3)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.623</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>1.000</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.537 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=391665">Homozygous familial hypercholesterolemia</a> associated with ABCG5.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001397, Hepatic steatosis</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0001397, Hepatic steatosis</dd><dd>HP:0001410, Decreased liver function - HP:0001397, Hepatic steatosis</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0001397, Hepatic steatosis</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0004381, Supravalvular aortic stenosis</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003077, Hyperlipidemia</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003141, Increased LDL cholesterol concentration</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0003077, Hyperlipidemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0001138, Optic neuropathy</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001397, Hepatic steatosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0004416, Precocious atherosclerosis</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.623 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=ABCG5">ABCG5</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000229, abnormal megakaryocyte differentiation</dd><dd>HP:0001903, Anemia - MP:0001585, hemolytic anemia</dd><dd>HP:0001541, Ascites - MP:0005606, increased bleeding time</dd><dd>HP:0010972, Anemia of inadequate production - MP:0000229, abnormal megakaryocyte differentiation</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0002417, abnormal megakaryocyte morphology</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia - MP:0002417, abnormal megakaryocyte morphology</dd><dd>HP:0001642, Pulmonic stenosis - MP:0003141, cardiac fibrosis</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0000180, abnormal circulating cholesterol level</dd><dd>HP:0001873, Thrombocytopenia - MP:0003179, thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0005065, abnormal neutrophil morphology</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.525 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ABCG5%0DABCC6&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to ABCC6</a> and phenotypic similarity 0.632 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=51608">Generalized arterial calcification of infancy</a> associated with ABCC6.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0006559, Hepatic calcification</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - HP:0001541, Ascites</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0004912, Hypophosphatemic rickets</dd><dd>HP:0001396, Cholestasis - HP:0006559, Hepatic calcification</dd><dd>HP:0001410, Decreased liver function - HP:0006559, Hepatic calcification</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0010639, Elevated alkaline phosphatase of bone origin</dd><dd>HP:0001399, Hepatic failure - HP:0006559, Hepatic calcification</dd><dd>HP:0000938, Osteopenia - HP:0002749, Osteomalacia</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001714, Ventricular hypertrophy</dd><dd>HP:0200114, Metabolic alkalosis - HP:0000969, Edema</dd><dd>HP:0003073, Hypoalbuminemia - HP:0010639, Elevated alkaline phosphatase of bone origin</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0010639, Elevated alkaline phosphatase of bone origin</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0000969, Edema</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0010639, Elevated alkaline phosphatase of bone origin</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0010639, Elevated alkaline phosphatase of bone origin</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0006559, Hepatic calcification</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0002647, Aortic dissection</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001531, Failure to thrive in infancy</dd></dl><dl><dt>Proximity score 0.525 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ABCG5%0DABCC6&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to ABCC6</a> and phenotypic similarity 0.489 to mouse mutant of ABCC6.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005553, increased circulating creatinine level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0000186, decreased circulating HDL cholesterol level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0000186, decreased circulating HDL cholesterol level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0005553, increased circulating creatinine level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0006133, calcified artery</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.525 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ABCG5%0DABCC6&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to ABCC6</a> and phenotypic similarity 0.302 to fish mutant of ABCC6.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - ZP:0000038, pericardium edematous, abnormal</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - ZP:0013900, bone mineralization increased occurrence, abnormal</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia - ZP:0013900, bone mineralization increased occurrence, abnormal</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 1.59 (p-value: 0.002410)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/618666">OMIM:618666</a> Sitosterolemia 2 - autosomal recessive</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=391665">ORPHA:391665</a> Homozygous familial hypercholesterolemia - autosomal dominant/recessive</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.914</b>
+                                    <data>(p=1.4E-3)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.623</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>1.000</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.537 to ORPHA:391665 Homozygous familial hypercholesterolemia</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">FRAMESHIFT_ELONGATION</span>
+                            <b>INS</b>
+                            <b>2-43828041-G-GC [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs762031825">rs762031825</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 1.000</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000405322.8">ABCG5:ENST00000405322.8:c.575dup:p.(Ile193Hisfs*5)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>ExAC NFE: 0.0030%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="FBN2" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000138829">FBN2</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.882</b>
+                    <data>(p=2.7E-3)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.634</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.948</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.474 to <a href="http://www.omim.org/entry/121050">Contractural arachnodactyly, congenital</a> associated with FBN2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0000938, Osteopenia</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia - HP:0000938, Osteopenia</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001647, Bicuspid aortic valve</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0002616, Aortic root aneurysm</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.634 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=FBN2">FBN2</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000598, abnormal liver morphology</dd><dd>HP:0001903, Anemia - MP:0003179, thrombocytopenia</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0003179, thrombocytopenia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0003795, abnormal bone structure</dd><dd>HP:0001396, Cholestasis - MP:0000598, abnormal liver morphology</dd><dd>HP:0001410, Decreased liver function - MP:0000598, abnormal liver morphology</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000598, abnormal liver morphology</dd><dd>HP:0001399, Hepatic failure - MP:0000598, abnormal liver morphology</dd><dd>HP:0000938, Osteopenia - MP:0003795, abnormal bone structure</dd><dd>HP:0001642, Pulmonic stenosis - MP:0000266, abnormal heart morphology</dd><dd>HP:0200114, Metabolic alkalosis - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0008805, decreased circulating amylase level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0008805, decreased circulating amylase level</dd><dd>HP:0001873, Thrombocytopenia - MP:0003179, thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000598, abnormal liver morphology</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000598, abnormal liver morphology</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0002152, abnormal brain morphology</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000598, abnormal liver morphology</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0003179, thrombocytopenia</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.227 to zebrafish mutant involving <a href="http://zfin.org/action/quicksearch/query?query=FBN2">FBN2</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - ZP:0001452, trunk edematous, abnormal</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - ZP:0005691, dorsal aorta decreased diameter, abnormal</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=FBN2%0DADAM19&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to ADAM19</a> and phenotypic similarity 0.665 to mouse mutant of ADAM19.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0002754, dilated heart right ventricle</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - MP:0001785, edema</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0006128, pulmonary valve stenosis</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0000273, overriding aortic valve</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=FBN2%0DADAM19&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to ADAM19</a> and phenotypic similarity 0.249 to fish mutant of ADAM19.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - ZP:0107084, hindbrain decreased magnitude axonogenesis, abnormal</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.61 (p-value: 0.988800)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/121050">OMIM:121050</a> Contractural arachnodactyly, congenital - autosomal dominant</dd>
+<dd><a href="http://www.omim.org/entry/616118">OMIM:616118</a> Macular degeneration, early-onset - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=115">ORPHA:115</a> Congenital contractural arachnodactyly - autosomal dominant</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.882</b>
+                                    <data>(p=2.7E-3)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.634</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.948</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.474 to OMIM:121050 Contractural arachnodactyly, congenital</dt>
+                                
+                                    <dt>Phenotypic similarity 0.293 to ORPHA:115 Congenital contractural arachnodactyly</dt>
+                                
+                                    <dt>Phenotypic similarity 0.121 to OMIM:616118 Macular degeneration, early-onset</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>5-128301399-T-C [0/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting, PP3_Moderate]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.948</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000262464.9">FBN2:ENST00000262464.9:c.6029A&gt;G:p.(Asp2010Gly)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.94782615</dd>
+                                    
+                                    <dd>REVEL: 0.881</dd>
+                                    <dd>MVP: 0.948</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="GRN" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000030582">GRN</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.838</b>
+                    <data>(p=5.0E-3)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.555</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.998</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.538 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=100070">Progressive non-fluent aphasia</a> associated with GRN.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0002366, Abnormal lower motor neuron morphology</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001297, Stroke</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.555 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=GRN">GRN</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0008986, abnormal liver parenchyma morphology</dd><dd>HP:0001903, Anemia - MP:0008918, microgliosis</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0008918, microgliosis</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0008918, microgliosis</dd><dd>HP:0001396, Cholestasis - MP:0010080, abnormal hepatocyte physiology</dd><dd>HP:0001410, Decreased liver function - MP:0010080, abnormal hepatocyte physiology</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0010080, abnormal hepatocyte physiology</dd><dd>HP:0001399, Hepatic failure - MP:0010080, abnormal hepatocyte physiology</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - MP:0008918, microgliosis</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0010080, abnormal hepatocyte physiology</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0010080, abnormal hepatocyte physiology</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0002152, abnormal brain morphology</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0008986, abnormal liver parenchyma morphology</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0008918, microgliosis</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.346 to zebrafish mutant involving <a href="http://zfin.org/action/quicksearch/query?query=GRN">GRN</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - ZP:0000720, liver decreased size, abnormal</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - ZP:0004503, liver morphogenesis disrupted, abnormal</dd><dd>HP:0001410, Decreased liver function - ZP:0004503, liver morphogenesis disrupted, abnormal</dd><dd>HP:0002910, Elevated hepatic transaminase - ZP:0004503, liver morphogenesis disrupted, abnormal</dd><dd>HP:0001399, Hepatic failure - ZP:0004503, liver morphogenesis disrupted, abnormal</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - ZP:0004503, liver morphogenesis disrupted, abnormal</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - ZP:0004503, liver morphogenesis disrupted, abnormal</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - ZP:0002078, spinal cord decreased length, abnormal</dd><dd>HP:0006568, Increased hepatic glycogen content - ZP:0004501, hepatocyte differentiation disrupted, abnormal</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.26 (p-value: 0.763320)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/607485">OMIM:607485</a> Aphasia, primary progressive - autosomal dominant</dd>
+<dd><a href="http://www.omim.org/entry/614706">OMIM:614706</a> Ceroid lipofuscinosis, neuronal, 11 - autosomal recessive</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=100069">ORPHA:100069</a> Semantic dementia (susceptibility)</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=100070">ORPHA:100070</a> Progressive non-fluent aphasia (susceptibility)</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=275864">ORPHA:275864</a> Behavioral variant of frontotemporal dementia (susceptibility)</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.838</b>
+                                    <data>(p=5.0E-3)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.555</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.998</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.538 to ORPHA:100070 Progressive non-fluent aphasia</dt>
+                                
+                                    <dt>Phenotypic similarity 0.252 to OMIM:607485 Aphasia, primary progressive</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>17-44350469-T-C [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs774067739">rs774067739</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PP3_Strong]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.998</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000053867.8">GRN:ENST00000053867.8:c.490T&gt;C:p.(Cys164Arg)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.9999497</dd>
+                                    
+                                    <dd>REVEL: 0.940</dd>
+                                    <dd>MVP: 1.000</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>ExAC EAS: 0.0116%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="FABP2" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000145384">FABP2</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.785</b>
+                    <data>(p=8.3E-3)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.520</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>1.000</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.520 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=FABP2">FABP2</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0002981, increased liver weight</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - MP:0002981, increased liver weight</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0003402, decreased liver weight</dd><dd>HP:0001410, Decreased liver function - MP:0003402, decreased liver weight</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0003402, decreased liver weight</dd><dd>HP:0001399, Hepatic failure - MP:0003402, decreased liver weight</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005669, increased circulating leptin level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0005669, increased circulating leptin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0005179, decreased circulating cholesterol level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0005669, increased circulating leptin level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0003402, decreased liver weight</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0003402, decreased liver weight</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0003402, decreased liver weight</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0005658, increased susceptibility to diet-induced obesity</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=FABP2%0DSLCO1B3&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SLCO1B3</a> and phenotypic similarity 0.524 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=3111">Rotor syndrome</a> associated with SLCO1B3.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0031137, Storage in hepatocytes</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0000952, Jaundice</dd><dd>HP:0001410, Decreased liver function - HP:0000952, Jaundice</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0012379, Abnormal circulating enzyme concentration or activity</dd><dd>HP:0001399, Hepatic failure - HP:0000952, Jaundice</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - HP:0002904, Hyperbilirubinemia</dd><dd>HP:0003073, Hypoalbuminemia - HP:0002904, Hyperbilirubinemia</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0002904, Hyperbilirubinemia</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0002904, Hyperbilirubinemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0012379, Abnormal circulating enzyme concentration or activity</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0012379, Abnormal circulating enzyme concentration or activity</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0031137, Storage in hepatocytes</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=FABP2%0DSLCO1B3&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SLCO1B3</a> and phenotypic similarity 0.617 to mouse mutant of SLCO1B3.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000609, abnormal liver physiology</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0000609, abnormal liver physiology</dd><dd>HP:0001410, Decreased liver function - MP:0000609, abnormal liver physiology</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000609, abnormal liver physiology</dd><dd>HP:0001399, Hepatic failure - MP:0000609, abnormal liver physiology</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005568, increased circulating total protein level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0000199, abnormal circulating serum albumin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0005178, increased circulating cholesterol level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0005344, increased circulating bilirubin level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000609, abnormal liver physiology</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000609, abnormal liver physiology</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000609, abnormal liver physiology</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.785</b>
+                                    <data>(p=8.3E-3)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.520</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>1.000</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">FRAMESHIFT_TRUNCATION</span>
+                            <b>DEL</b>
+                            <b>4-119320758-TTGAC-T [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs780659556">rs780659556</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 1.000</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000274024.4">FABP2:ENST00000274024.4:c.148_151del:p.(Val50Lysfs*23)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>TOPMed: 0.0008%</dd>
+                                    <dd>ExAC NFE: 0.0030%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0027%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="ATXN3" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000066427">ATXN3</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.763</b>
+                    <data>(p=1.0E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.507</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>1.000</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.271 to <a href="http://www.omim.org/entry/109150">Machado-Joseph disease</a> associated with ATXN3.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - HP:0002171, Gliosis</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0002503, Spinocerebellar tract degeneration</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.284 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=ATXN3">ATXN3</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005343, increased circulating aspartate transaminase level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0005343, increased circulating aspartate transaminase level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0005343, increased circulating aspartate transaminase level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0005343, increased circulating aspartate transaminase level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.507 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ATXN3%0DTWNK&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to TWNK</a> and phenotypic similarity 0.609 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=254892">Autosomal dominant progressive external ophthalmoplegia</a> associated with TWNK.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001392, Abnormality of the liver</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - HP:0000969, Edema</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0000939, Osteoporosis</dd><dd>HP:0001396, Cholestasis - HP:0001392, Abnormality of the liver</dd><dd>HP:0001410, Decreased liver function - HP:0001392, Abnormality of the liver</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0001399, Hepatic failure - HP:0001392, Abnormality of the liver</dd><dd>HP:0000938, Osteopenia - HP:0000939, Osteoporosis</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001712, Left ventricular hypertrophy</dd><dd>HP:0200114, Metabolic alkalosis - HP:0002151, Increased serum lactate</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003236, Elevated circulating creatine kinase concentration</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003236, Elevated circulating creatine kinase concentration</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0002151, Increased serum lactate</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0009830, Peripheral neuropathy</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0000819, Diabetes mellitus</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001508, Failure to thrive</dd></dl><dl><dt>PhenIX semantic similarity score: 0.38 (p-value: 0.943010)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/109150">OMIM:109150</a> Machado-Joseph disease - autosomal dominant</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.763</b>
+                                    <data>(p=1.0E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.507</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>1.000</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.271 to OMIM:109150 Machado-Joseph disease</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">FRAMESHIFT_ELONGATION</span>
+                            <b>INS</b>
+                            <b>14-92071010-C-CTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTG [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs1555397062">rs1555397062</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                <span class="label label-warning">LIKELY_PATHOGENIC</span>
+                                
+                                
+                                
+                                <b>[PVS1, PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 1.000</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000644486.2">ATXN3:ENST00000644486.2:c.915_916insCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCA:p.(Gly306Glnfs*38)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="CILK1" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000112144">CILK1</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.749</b>
+                    <data>(p=1.2E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>1.000</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.220 to <a href="http://www.omim.org/entry/612651">Endocrine-cerebroosteodysplasia</a> associated with CILK1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0000835, Adrenal hypoplasia</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - HP:0032471, Focal polymicrogyria</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0000835, Adrenal hypoplasia</dd><dd>HP:0001410, Decreased liver function - HP:0000835, Adrenal hypoplasia</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0000835, Adrenal hypoplasia</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0032471, Focal polymicrogyria</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0000835, Adrenal hypoplasia</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.370 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=CILK1">CILK1</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - MP:0001785, edema</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0002896, abnormal bone mineralization</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia - MP:0002896, abnormal bone mineralization</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0012676, dilated brain ventricle</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0000547, short limbs</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=CILK1%0DCPOX&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to CPOX</a> and phenotypic similarity 0.498 to <a href="http://www.omim.org/entry/618892">Harderoporphyria</a> associated with CPOX.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001744, Splenomegaly</dd><dd>HP:0001903, Anemia - HP:0001878, Hemolytic anemia</dd><dd>HP:0001541, Ascites - HP:0002240, Hepatomegaly</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001878, Hemolytic anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001878, Hemolytic anemia</dd><dd>HP:0001396, Cholestasis - HP:0006579, Prolonged neonatal jaundice</dd><dd>HP:0001410, Decreased liver function - HP:0002240, Hepatomegaly</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0002240, Hepatomegaly</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - HP:0003265, Neonatal hyperbilirubinemia</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003281, Increased circulating ferritin concentration</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003281, Increased circulating ferritin concentration</dd><dd>HP:0001873, Thrombocytopenia - HP:0001923, Reticulocytosis</dd><dd>HP:0002151, Increased serum lactate - HP:0003265, Neonatal hyperbilirubinemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0002240, Hepatomegaly</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001878, Hemolytic anemia</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=CILK1%0DCPOX&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to CPOX</a> and phenotypic similarity 0.675 to mouse mutant of CPOX.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000691, enlarged spleen</dd><dd>HP:0001903, Anemia - MP:0002591, decreased mean corpuscular volume</dd><dd>HP:0001541, Ascites - MP:0000691, enlarged spleen</dd><dd>HP:0010972, Anemia of inadequate production - MP:0002810, microcytic anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0011178, increased erythroblast number</dd><dd>HP:0001396, Cholestasis - MP:0008476, increased spleen red pulp amount</dd><dd>HP:0001410, Decreased liver function - MP:0008476, increased spleen red pulp amount</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0008476, increased spleen red pulp amount</dd><dd>HP:0001399, Hepatic failure - MP:0008476, increased spleen red pulp amount</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - MP:0011890, increased circulating ferritin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0011890, increased circulating ferritin level</dd><dd>HP:0001873, Thrombocytopenia - MP:0002447, abnormal erythrocyte morphology</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0008476, increased spleen red pulp amount</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0008476, increased spleen red pulp amount</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0008476, increased spleen red pulp amount</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0002447, abnormal erythrocyte morphology</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.08 (p-value: 1.000000)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/612651">OMIM:612651</a> Endocrine-cerebroosteodysplasia - autosomal recessive</dd>
+<dd><a href="http://www.omim.org/entry/617924">OMIM:617924</a> Epilepsy, juvenile myoclonic, susceptibility to, 10 (susceptibility)</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=307">ORPHA:307</a> Juvenile myoclonic epilepsy - autosomal dominant</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.749</b>
+                                    <data>(p=1.2E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>1.000</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">FRAMESHIFT_TRUNCATION</span>
+                            <b>DEL</b>
+                            <b>6-53006378-TC-T [0/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 1.000</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000676107.1">CILK1:ENST00000676107.1:c.1680del:p.(Glu563Lysfs*11)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.564</b>
+                                    <data>(p=7.8E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.909</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.220 to OMIM:612651 Endocrine-cerebroosteodysplasia</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">FRAMESHIFT_TRUNCATION</span>
+                            <b>DEL</b>
+                            <b>6-53006378-TC-T [0/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                <span class="label label-warning">LIKELY_PATHOGENIC</span>
+                                
+                                
+                                
+                                <b>[PVS1, PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 1.000</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000676107.1">CILK1:ENST00000676107.1:c.1680del:p.(Glu563Lysfs*11)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>6-53006371-T-C [0/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.818</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000676107.1">CILK1:ENST00000676107.1:c.1688A&gt;G:p.(Glu563Gly)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.8177741</dd>
+                                    
+                                    <dd>REVEL: 0.584</dd>
+                                    <dd>MVP: 0.818</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="DIAPH2" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000147202">DIAPH2</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.749</b>
+                    <data>(p=1.2E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>1.000</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.177 to <a href="http://www.omim.org/entry/300511">?Premature ovarian failure 2A</a> associated with DIAPH2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0008232, Elevated circulating follicle stimulating hormone level</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0008232, Elevated circulating follicle stimulating hormone level</dd><dd>HP:0001410, Decreased liver function - HP:0008209, Premature ovarian insufficiency</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0008209, Premature ovarian insufficiency</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - HP:0008232, Elevated circulating follicle stimulating hormone level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0008232, Elevated circulating follicle stimulating hormone level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0008232, Elevated circulating follicle stimulating hormone level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0008232, Elevated circulating follicle stimulating hormone level</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.222 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=DIAPH2">DIAPH2</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0001566, increased circulating phosphate level</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0001566, increased circulating phosphate level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=DIAPH2%0DSLC20A1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SLC20A1</a> and phenotypic similarity 0.604 to mouse mutant of SLC20A1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000691, enlarged spleen</dd><dd>HP:0001903, Anemia - MP:0001577, anemia</dd><dd>HP:0001541, Ascites - MP:0000691, enlarged spleen</dd><dd>HP:0010972, Anemia of inadequate production - MP:0000245, abnormal erythropoiesis</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0002896, abnormal bone mineralization</dd><dd>HP:0001396, Cholestasis - MP:0000689, abnormal spleen morphology</dd><dd>HP:0001410, Decreased liver function - MP:0000689, abnormal spleen morphology</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000689, abnormal spleen morphology</dd><dd>HP:0001399, Hepatic failure - MP:0000689, abnormal spleen morphology</dd><dd>HP:0000938, Osteopenia - MP:0002896, abnormal bone mineralization</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002874, decreased hemoglobin content</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0005280, abnormal fatty acids level</dd><dd>HP:0001873, Thrombocytopenia - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000689, abnormal spleen morphology</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000689, abnormal spleen morphology</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000689, abnormal spleen morphology</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0000245, abnormal erythropoiesis</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001732, postnatal growth retardation</dd></dl><dl><dt>PhenIX semantic similarity score: 0.01 (p-value: 0.858070)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/300511">OMIM:300511</a> ?Premature ovarian failure 2A (unconfirmed)</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>X_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.749</b>
+                                    <data>(p=1.2E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>1.000</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.177 to OMIM:300511 ?Premature ovarian failure 2A</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">STOP_GAINED</span>
+                            <b>SNV</b>
+                            <b>X-97348134-C-T [0/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                <span class="label label-warning">LIKELY_PATHOGENIC</span>
+                                
+                                
+                                
+                                <b>[PVS1, PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 1.000</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000324765.13">DIAPH2:ENST00000324765.13:c.2863C&gt;T:p.(Arg955*)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>X_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.182</b>
+                                    <data>(p=2.3E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.250</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>1.000</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">STOP_GAINED</span>
+                            <b>SNV</b>
+                            <b>X-97348134-C-T [0/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 1.000</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000324765.13">DIAPH2:ENST00000324765.13:c.2863C&gt;T:p.(Arg955*)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="ANKFN1" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000153930">ANKFN1</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.749</b>
+                    <data>(p=1.3E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>1.000</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.265 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=ANKFN1">ANKFN1</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001262, decreased body weight</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ANKFN1%0DSIRPG&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SIRPG</a> and phenotypic similarity 0.619 to mouse mutant of SIRPG.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0002628, hepatic steatosis</dd><dd>HP:0001903, Anemia - MP:0003179, thrombocytopenia</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0003179, thrombocytopenia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0008254, increased megakaryocyte cell number</dd><dd>HP:0001396, Cholestasis - MP:0002628, hepatic steatosis</dd><dd>HP:0001410, Decreased liver function - MP:0002628, hepatic steatosis</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0002628, hepatic steatosis</dd><dd>HP:0001399, Hepatic failure - MP:0002628, hepatic steatosis</dd><dd>HP:0000938, Osteopenia - MP:0008254, increased megakaryocyte cell number</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0002628, hepatic steatosis</dd><dd>HP:0001873, Thrombocytopenia - MP:0003179, thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0002628, hepatic steatosis</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0002628, hepatic steatosis</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0002628, hepatic steatosis</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0005018, decreased T cell number</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001262, decreased body weight</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.749</b>
+                                    <data>(p=1.3E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>1.000</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">FRAMESHIFT_VARIANT</span>
+                            <b>DEL</b>
+                            <b>17-56374681-AG-A [0/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 1.000</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000682825.1">ANKFN1:ENST00000682825.1:c.878del:p.(Ser293Thrfs*6)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="GLT8D1" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000016864">GLT8D1</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.748</b>
+                    <data>(p=1.3E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>1.000</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.464 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=803">Amyotrophic lateral sclerosis</a> associated with GLT8D1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - HP:0000217, Xerostomia</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function - HP:0000217, Xerostomia</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0000217, Xerostomia</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - HP:0000217, Xerostomia</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0000217, Xerostomia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0007373, Motor neuron atrophy</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=GLT8D1%0DSRP54&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SRP54</a> and phenotypic similarity 0.676 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=811">Shwachman-Diamond syndrome</a> associated with SRP54.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0002240, Hepatomegaly</dd><dd>HP:0001903, Anemia - HP:0001903, Anemia</dd><dd>HP:0001541, Ascites - HP:0002240, Hepatomegaly</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001897, Normocytic anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0005528, Bone marrow hypocellularity</dd><dd>HP:0001396, Cholestasis - HP:0002240, Hepatomegaly</dd><dd>HP:0001410, Decreased liver function - HP:0001738, Exocrine pancreatic insufficiency</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0001399, Hepatic failure - HP:0001738, Exocrine pancreatic insufficiency</dd><dd>HP:0000938, Osteopenia - HP:0000938, Osteopenia</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001627, Abnormal heart morphology</dd><dd>HP:0200114, Metabolic alkalosis - HP:0012202, Increased serum bile acid concentration</dd><dd>HP:0003073, Hypoalbuminemia - HP:0410289, Hypoamylasemia</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0012202, Increased serum bile acid concentration</dd><dd>HP:0001873, Thrombocytopenia - HP:0001873, Thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate - HP:0012202, Increased serum bile acid concentration</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0002240, Hepatomegaly</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0040238, Impaired neutrophil chemotaxis</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001508, Failure to thrive</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=GLT8D1%0DSRP54&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SRP54</a> and phenotypic similarity 0.196 to fish mutant of SRP54.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - ZP:0002029, pancreas development disrupted, abnormal</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - ZP:0002029, pancreas development disrupted, abnormal</dd><dd>HP:0001410, Decreased liver function - ZP:0002029, pancreas development disrupted, abnormal</dd><dd>HP:0002910, Elevated hepatic transaminase - ZP:0002029, pancreas development disrupted, abnormal</dd><dd>HP:0001399, Hepatic failure - ZP:0002029, pancreas development disrupted, abnormal</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - ZP:0002029, pancreas development disrupted, abnormal</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - ZP:0002029, pancreas development disrupted, abnormal</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - ZP:0002029, pancreas development disrupted, abnormal</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=803">ORPHA:803</a> Amyotrophic lateral sclerosis (susceptibility)</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.748</b>
+                                    <data>(p=1.3E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>1.000</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.464 to ORPHA:803 Amyotrophic lateral sclerosis</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">FRAMESHIFT_ELONGATION</span>
+                            <b>INS</b>
+                            <b>3-52697811-G-GC [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs754869681">rs754869681</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                <span class="label label-warning">LIKELY_PATHOGENIC</span>
+                                
+                                
+                                
+                                <b>[PVS1]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 1.000</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000266014.11">GLT8D1:ENST00000266014.11:c.238dup:p.(Ala80Glyfs*37)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>gnomAD_E_SAS: 0.0032%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="PTPN7" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000143851">PTPN7</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.748</b>
+                    <data>(p=1.3E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.999</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=PTPN7%0DDUSP16&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to DUSP16</a> and phenotypic similarity 0.644 to mouse mutant of DUSP16.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000691, enlarged spleen</dd><dd>HP:0001903, Anemia - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0001541, Ascites - MP:0000691, enlarged spleen</dd><dd>HP:0010972, Anemia of inadequate production - MP:0002874, decreased hemoglobin content</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0003795, abnormal bone structure</dd><dd>HP:0001396, Cholestasis - MP:0000691, enlarged spleen</dd><dd>HP:0001410, Decreased liver function - MP:0000691, enlarged spleen</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000691, enlarged spleen</dd><dd>HP:0001399, Hepatic failure - MP:0000691, enlarged spleen</dd><dd>HP:0000938, Osteopenia - MP:0003795, abnormal bone structure</dd><dd>HP:0001642, Pulmonic stenosis - MP:0002833, increased heart weight</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005344, increased circulating bilirubin level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002874, decreased hemoglobin content</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0000186, decreased circulating HDL cholesterol level</dd><dd>HP:0001873, Thrombocytopenia - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0002151, Increased serum lactate - MP:0005344, increased circulating bilirubin level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000691, enlarged spleen</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000691, enlarged spleen</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000691, enlarged spleen</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.748</b>
+                                    <data>(p=1.3E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.999</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">STOP_GAINED</span>
+                            <b>SNV</b>
+                            <b>1-202159294-G-A [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs149516769">rs149516769</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.999</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000691036.1">PTPN7:ENST00000691036.1:c.109C&gt;T:p.(Arg37*)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>TOPMed: 0.0011%</dd>
+                                    <dd>ExAC NFE: 0.0030%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0036%</dd>
+                                    <dd>gnomAD_G_NFE: 0.0067%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="ALDH1L2" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000136010">ALDH1L2</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.666</b>
+                    <data>(p=4.3E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.503</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.953</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.442 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=ALDH1L2">ALDH1L2</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0002628, hepatic steatosis</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0002628, hepatic steatosis</dd><dd>HP:0001410, Decreased liver function - MP:0002628, hepatic steatosis</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0002628, hepatic steatosis</dd><dd>HP:0001399, Hepatic failure - MP:0002628, hepatic steatosis</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0014174, decreased fatty acid beta-oxidation</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0002628, hepatic steatosis</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0002628, hepatic steatosis</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0002628, hepatic steatosis</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.503 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ALDH1L2%0DDHFR&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to DHFR</a> and phenotypic similarity 0.632 to <a href="http://www.omim.org/entry/613839">Megaloblastic anemia due to dihydrofolate reductase deficiency</a> associated with DHFR.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0002240, Hepatomegaly</dd><dd>HP:0001903, Anemia - HP:0005518, Increased mean corpuscular volume</dd><dd>HP:0001541, Ascites - HP:0002240, Hepatomegaly</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001889, Megaloblastic anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001876, Pancytopenia</dd><dd>HP:0001396, Cholestasis - HP:0000952, Jaundice</dd><dd>HP:0001410, Decreased liver function - HP:0000952, Jaundice</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0025435, Increased circulating lactate dehydrogenase concentration</dd><dd>HP:0001399, Hepatic failure - HP:0000952, Jaundice</dd><dd>HP:0000938, Osteopenia - HP:0001876, Pancytopenia</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - HP:0040087, Abnormal blood folate concentration</dd><dd>HP:0003073, Hypoalbuminemia - HP:0040087, Abnormal blood folate concentration</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0040087, Abnormal blood folate concentration</dd><dd>HP:0001873, Thrombocytopenia - HP:0001873, Thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate - HP:0040087, Abnormal blood folate concentration</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0025435, Increased circulating lactate dehydrogenase concentration</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0025435, Increased circulating lactate dehydrogenase concentration</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0002240, Hepatomegaly</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001876, Pancytopenia</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0005484, Secondary microcephaly</dd></dl><dl><dt>Proximity score 0.503 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ALDH1L2%0DDHFR&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to DHFR</a> and phenotypic similarity 0.536 to mouse mutant of DHFR.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000600, liver hypoplasia</dd><dd>HP:0001903, Anemia - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0008813, decreased common myeloid progenitor cell number</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0013697, decreased granulocyte monocyte progenitor cell number</dd><dd>HP:0001396, Cholestasis - MP:0000603, pale liver</dd><dd>HP:0001410, Decreased liver function - MP:0000603, pale liver</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000603, pale liver</dd><dd>HP:0001399, Hepatic failure - MP:0000603, pale liver</dd><dd>HP:0000938, Osteopenia - MP:0013697, decreased granulocyte monocyte progenitor cell number</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000603, pale liver</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000603, pale liver</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000600, liver hypoplasia</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0009395, increased nucleated erythrocyte cell number</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.503 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ALDH1L2%0DDHFR&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to DHFR</a> and phenotypic similarity 0.318 to fish mutant of DHFR.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - ZP:0001466, ventral region whole organism edematous, abnormal</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - ZP:0000486, cardiac ventricle structure, abnormal</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - ZP:0017548, axis elongation decreased rate, abnormal</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.666</b>
+                                    <data>(p=4.3E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.503</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.953</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>12-105038171-G-A [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs373348266">rs373348266</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PP3_Moderate]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=2352335%5Balleleid%5D">(criteria provided, single submitter)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.953</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000258494.14">ALDH1L2:ENST00000258494.14:c.2077C&gt;T:p.(Leu693Phe)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.9617639</dd>
+                                    
+                                    <dd>REVEL: 0.826</dd>
+                                    <dd>MVP: 0.962</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>TOPMed: 0.0121%</dd>
+                                    <dd>ESP AA: 0.0681%</dd>
+                                    <dd>ESP All: 0.0231%</dd>
+                                    <dd>ExAC AFR: 0.0484%</dd>
+                                    <dd>gnomAD_E_AFR: 0.0654%</dd>
+                                    <dd>gnomAD_G_AFR: 0.0230%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="NOX5" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000255346">NOX5</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.663</b>
+                    <data>(p=4.4E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.501</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.954</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.123 to zebrafish mutant involving <a href="http://zfin.org/action/quicksearch/query?query=NOX5">NOX5</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - ZP:0005361, cranial nerve II decreased thickness, abnormal</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.501 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=NOX5%0DNOS3&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to NOS3</a> and phenotypic similarity 0.527 to <a href="http://www.omim.org/entry/189800">Hypertension, pregnancy-induced</a> associated with NOS3.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001873, Thrombocytopenia</dd><dd>HP:0001903, Anemia - HP:0001873, Thrombocytopenia</dd><dd>HP:0001541, Ascites - HP:0000969, Edema</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001873, Thrombocytopenia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001873, Thrombocytopenia</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0000822, Hypertension</dd><dd>HP:0200114, Metabolic alkalosis - HP:0000969, Edema</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - HP:0001873, Thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate - HP:0000969, Edema</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001873, Thrombocytopenia</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.501 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=NOX5%0DNOS3&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to NOS3</a> and phenotypic similarity 0.605 to mouse mutant of NOS3.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000607, abnormal hepatocyte morphology</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0001125, abnormal oocyte morphology</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0009345, abnormal trabecular bone thickness</dd><dd>HP:0001396, Cholestasis - MP:0000609, abnormal liver physiology</dd><dd>HP:0001410, Decreased liver function - MP:0000609, abnormal liver physiology</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000609, abnormal liver physiology</dd><dd>HP:0001399, Hepatic failure - MP:0000609, abnormal liver physiology</dd><dd>HP:0000938, Osteopenia - MP:0000063, decreased bone mineral density</dd><dd>HP:0001642, Pulmonic stenosis - MP:0003921, abnormal heart left ventricle morphology</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002727, decreased circulating insulin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0005182, increased circulating estradiol level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000609, abnormal liver physiology</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000609, abnormal liver physiology</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0002882, abnormal neuron morphology</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0002628, hepatic steatosis</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001262, decreased body weight</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.663</b>
+                                    <data>(p=4.4E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.501</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.954</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>15-69035456-G-A [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs748636955">rs748636955</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.954</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000388866.8">NOX5:ENST00000388866.8:c.958G&gt;A:p.(Val320Met)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.9551393</dd>
+                                    
+                                    <dd>REVEL: 0.328</dd>
+                                    <dd>MVP: 0.955</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>ExAC AMR: 0.0087%</dd>
+                                    <dd>ExAC NFE: 0.0030%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0018%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0032%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="PROZ" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000126231">PROZ</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.647</b>
+                    <data>(p=5.0E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.501</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.946</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.223 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=PROZ">PROZ</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - MP:0031121, increased susceptibility to induced thrombosis</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.501 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=PROZ%0DABCC6&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to ABCC6</a> and phenotypic similarity 0.632 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=51608">Generalized arterial calcification of infancy</a> associated with ABCC6.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0006559, Hepatic calcification</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - HP:0001541, Ascites</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0004912, Hypophosphatemic rickets</dd><dd>HP:0001396, Cholestasis - HP:0006559, Hepatic calcification</dd><dd>HP:0001410, Decreased liver function - HP:0006559, Hepatic calcification</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0010639, Elevated alkaline phosphatase of bone origin</dd><dd>HP:0001399, Hepatic failure - HP:0006559, Hepatic calcification</dd><dd>HP:0000938, Osteopenia - HP:0002749, Osteomalacia</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001714, Ventricular hypertrophy</dd><dd>HP:0200114, Metabolic alkalosis - HP:0000969, Edema</dd><dd>HP:0003073, Hypoalbuminemia - HP:0010639, Elevated alkaline phosphatase of bone origin</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0010639, Elevated alkaline phosphatase of bone origin</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0000969, Edema</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0010639, Elevated alkaline phosphatase of bone origin</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0010639, Elevated alkaline phosphatase of bone origin</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0006559, Hepatic calcification</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0002647, Aortic dissection</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001531, Failure to thrive in infancy</dd></dl><dl><dt>Proximity score 0.501 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=PROZ%0DABCC6&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to ABCC6</a> and phenotypic similarity 0.489 to mouse mutant of ABCC6.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005553, increased circulating creatinine level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0000186, decreased circulating HDL cholesterol level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0000186, decreased circulating HDL cholesterol level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0005553, increased circulating creatinine level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0006133, calcified artery</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.501 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=PROZ%0DABCC6&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to ABCC6</a> and phenotypic similarity 0.302 to fish mutant of ABCC6.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - ZP:0000038, pericardium edematous, abnormal</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - ZP:0013900, bone mineralization increased occurrence, abnormal</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia - ZP:0013900, bone mineralization increased occurrence, abnormal</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.647</b>
+                                    <data>(p=5.0E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.501</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.946</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>13-113164614-G-T [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs375926497">rs375926497</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.946</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000375547.7">PROZ:ENST00000375547.7:c.475G&gt;T:p.(Gly159Cys)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.95580864</dd>
+                                    
+                                    <dd>REVEL: 0.537</dd>
+                                    <dd>MVP: 0.956</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0156%</dd>
+                                    <dd>TOPMed: 0.0004%</dd>
+                                    <dd>ExAC EAS: 0.0701%</dd>
+                                    <dd>ExAC NFE: 0.0015%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0464%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0009%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="SCN4A" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000007314">SCN4A</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.644</b>
+                    <data>(p=5.1E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.502</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.944</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.526 to <a href="http://www.omim.org/entry/620369">Congenital myopathy 22B, severe fetal</a> associated with SCN4A.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0002240, Hepatomegaly</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - HP:0001541, Ascites</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0002240, Hepatomegaly</dd><dd>HP:0001410, Decreased liver function - HP:0002240, Hepatomegaly</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0002240, Hepatomegaly</dd><dd>HP:0000938, Osteopenia - HP:0002987, Elbow flexion contracture</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - HP:0002202, Pleural effusion</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0002202, Pleural effusion</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0002240, Hepatomegaly</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001790, Nonimmune hydrops fetalis</dd></dl><dl><dt>Phenotypic similarity 0.415 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=SCN4A">SCN4A</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia - MP:0008935, decreased mean platelet volume</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0008935, decreased mean platelet volume</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function - MP:0002966, decreased circulating alkaline phosphatase level</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0002966, decreased circulating alkaline phosphatase level</dd><dd>HP:0001399, Hepatic failure - MP:0002966, decreased circulating alkaline phosphatase level</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - MP:0008806, increased circulating amylase level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0008806, increased circulating amylase level</dd><dd>HP:0001873, Thrombocytopenia - MP:0008935, decreased mean platelet volume</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0002966, decreased circulating alkaline phosphatase level</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0002966, decreased circulating alkaline phosphatase level</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0008935, decreased mean platelet volume</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.502 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=SCN4A%0DGLRB&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to GLRB</a> and phenotypic similarity 0.163 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=3197">Hereditary hyperekplexia</a> associated with GLRB.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia - HP:0001387, Joint stiffness</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.502 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=SCN4A%0DGLRB&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to GLRB</a> and phenotypic similarity 0.618 to mouse mutant of GLRB.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0004952, increased spleen weight</dd><dd>HP:0001903, Anemia - MP:0000219, increased neutrophil cell number</dd><dd>HP:0001541, Ascites - MP:0004952, increased spleen weight</dd><dd>HP:0010972, Anemia of inadequate production - MP:0000219, increased neutrophil cell number</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0000219, increased neutrophil cell number</dd><dd>HP:0001396, Cholestasis - MP:0004952, increased spleen weight</dd><dd>HP:0001410, Decreased liver function - MP:0002966, decreased circulating alkaline phosphatase level</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0002966, decreased circulating alkaline phosphatase level</dd><dd>HP:0001399, Hepatic failure - MP:0002966, decreased circulating alkaline phosphatase level</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0002833, increased heart weight</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005343, increased circulating aspartate transaminase level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0005419, decreased circulating serum albumin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0005419, decreased circulating serum albumin level</dd><dd>HP:0001873, Thrombocytopenia - MP:0000219, increased neutrophil cell number</dd><dd>HP:0002151, Increased serum lactate - MP:0005343, increased circulating aspartate transaminase level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0002966, decreased circulating alkaline phosphatase level</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0002966, decreased circulating alkaline phosphatase level</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0004952, increased spleen weight</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0000219, increased neutrophil cell number</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.79 (p-value: 0.991310)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/168300">OMIM:168300</a> Paramyotonia congenita - autosomal dominant</dd>
+<dd><a href="http://www.omim.org/entry/170500">OMIM:170500</a> Hyperkalemic periodic paralysis - autosomal dominant</dd>
+<dd><a href="http://www.omim.org/entry/608390">OMIM:608390</a> Myotonia congenita, atypical, acetazolamide-responsive - autosomal dominant</dd>
+<dd><a href="http://www.omim.org/entry/613345">OMIM:613345</a> Hypokalemic periodic paralysis, type 2 - autosomal dominant</dd>
+<dd><a href="http://www.omim.org/entry/614198">OMIM:614198</a> Myasthenic syndrome, congenital, 16 - autosomal recessive</dd>
+<dd><a href="http://www.omim.org/entry/620351">OMIM:620351</a> Congenital myopathy 22A, classic - autosomal recessive</dd>
+<dd><a href="http://www.omim.org/entry/620369">OMIM:620369</a> Congenital myopathy 22B, severe fetal - autosomal recessive</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=681">ORPHA:681</a> Hypokalemic periodic paralysis - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=682">ORPHA:682</a> Hyperkalemic periodic paralysis - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=684">ORPHA:684</a> Paramyotonia congenita of Von Eulenburg - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=98913">ORPHA:98913</a> Postsynaptic congenital myasthenic syndromes - autosomal recessive</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=99734">ORPHA:99734</a> Myotonia fluctuans - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=99735">ORPHA:99735</a> Myotonia permanens - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=99736">ORPHA:99736</a> Acetazolamide-responsive myotonia - autosomal dominant</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.644</b>
+                                    <data>(p=5.1E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.502</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.944</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.326 to ORPHA:681 Hypokalemic periodic paralysis</dt>
+                                
+                                    <dt>Phenotypic similarity 0.307 to ORPHA:682 Hyperkalemic periodic paralysis</dt>
+                                
+                                    <dt>Phenotypic similarity 0.266 to OMIM:608390 Myotonia congenita, atypical, acetazolamide-responsive</dt>
+                                
+                                    <dt>Phenotypic similarity 0.228 to ORPHA:99736 Acetazolamide-responsive myotonia</dt>
+                                
+                                    <dt>Phenotypic similarity 0.193 to ORPHA:684 Paramyotonia congenita of Von Eulenburg</dt>
+                                
+                                    <dt>Phenotypic similarity 0.184 to OMIM:613345 Hypokalemic periodic paralysis, type 2</dt>
+                                
+                                    <dt>Phenotypic similarity 0.184 to OMIM:170500 Hyperkalemic periodic paralysis</dt>
+                                
+                                    <dt>Phenotypic similarity 0.167 to ORPHA:99735 Myotonia permanens</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>17-63943777-T-C [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs754942929">rs754942929</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PP3_Moderate]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=2105407%5Balleleid%5D">(criteria provided, single submitter)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.944</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000435607.3">SCN4A:ENST00000435607.3:c.3986A&gt;G:p.(Lys1329Arg)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.9467736</dd>
+                                    
+                                    <dd>REVEL: 0.871</dd>
+                                    <dd>MVP: 0.947</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>TOPMed: 0.0008%</dd>
+                                    <dd>ExAC SAS: 0.0246%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0058%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0228%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.173</b>
+                                    <data>(p=2.3E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.526</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.681</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.526 to OMIM:620369 Congenital myopathy 22B, severe fetal</dt>
+                                
+                                    <dt>Phenotypic similarity 0.409 to OMIM:620351 Congenital myopathy 22A, classic</dt>
+                                
+                                    <dt>Phenotypic similarity 0.198 to ORPHA:98913 Postsynaptic congenital myasthenic syndromes</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>17-63943777-T-C [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs754942929">rs754942929</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PP3_Moderate]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=2105407%5Balleleid%5D">(criteria provided, single submitter)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.944</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000435607.3">SCN4A:ENST00000435607.3:c.3986A&gt;G:p.(Lys1329Arg)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.9467736</dd>
+                                    
+                                    <dd>REVEL: 0.871</dd>
+                                    <dd>MVP: 0.947</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>TOPMed: 0.0008%</dd>
+                                    <dd>ExAC SAS: 0.0246%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0058%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0228%</dd>
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>17-63940814-G-C [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs376833596">rs376833596</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                
+                                
+                                
+                                
+                                <span class="label label-default">CONFLICTING_PATHOGENICITY_INTERPRETATIONS</span>
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=506287%5Balleleid%5D">(criteria provided, conflicting interpretations)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.417</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000435607.3">SCN4A:ENST00000435607.3:c.5468C&gt;G:p.(Pro1823Arg)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.44369525</dd>
+                                    
+                                    <dd>REVEL: 0.242</dd>
+                                    <dd>MVP: 0.444</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.1874%</dd>
+                                    <dd>TOPMed: 0.0159%</dd>
+                                    <dd>ExAC AFR: 0.0209%</dd>
+                                    <dd>ExAC EAS: 0.2906%</dd>
+                                    <dd>ExAC SAS: 0.3627%</dd>
+                                    <dd>gnomAD_E_AFR: 0.0200%</dd>
+                                    <dd>gnomAD_E_EAS: 0.2990%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0009%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0747%</dd>
+                                    <dd>gnomAD_E_SAS: 0.3349%</dd>
+                                    <dd>gnomAD_G_AFR: 0.0115%</dd>
+                                    <dd>gnomAD_G_EAS: 0.2466%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+                <div class="row">
+                    <div class="col-sm-12">
+                        <b>Other passed variants:</b>
+                    </div>
+                </div>
+                
+                
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                        <b>SNV</b>
+                        <b>17-63959349-G-A [0/1]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs181494727">rs181494727</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    <div class="col-sm-12">
+                        <b>ClinVar: </b>
+                        
+                        
+                            <span class="label label-success">BENIGN_OR_LIKELY_BENIGN</span>
+                            
+                            
+                            
+                            
+                            
+                            <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=442005%5Balleleid%5D">(criteria provided, multiple submitters, no conflicts)</a>
+                        
+                    </div>
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.091</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000435607.3">SCN4A:ENST00000435607.3:c.1935C&gt;T:p.(=)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            
+                            <dd>1000Genomes: 0.0625%</dd>
+                            <dd>TOPMed: 0.0246%</dd>
+                            <dd>ExAC EAS: 0.2670%</dd>
+                            <dd>ExAC SAS: 0.0122%</dd>
+                            <dd>gnomAD_E_EAS: 0.3015%</dd>
+                            <dd>gnomAD_E_NFE: 0.0009%</dd>
+                            <dd>gnomAD_E_OTH: 0.0183%</dd>
+                            <dd>gnomAD_E_SAS: 0.0130%</dd>
+                            <dd>gnomAD_G_EAS: 0.4932%</dd>
+                        </dl>
+                    </div>
+                </div>
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="ACSS2" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000131069">ACSS2</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.631</b>
+                    <data>(p=5.5E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.507</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.932</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Proximity score 0.507 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ACSS2%0DPCCB&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to PCCB</a> and phenotypic similarity 0.611 to <a href="http://www.omim.org/entry/606054">Propionicacidemia</a> associated with PCCB.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0002240, Hepatomegaly</dd><dd>HP:0001903, Anemia - HP:0001903, Anemia</dd><dd>HP:0001541, Ascites - HP:0001944, Dehydration</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001903, Anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001876, Pancytopenia</dd><dd>HP:0001396, Cholestasis - HP:0002240, Hepatomegaly</dd><dd>HP:0001410, Decreased liver function - HP:0002240, Hepatomegaly</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0003353, Propionyl-CoA carboxylase deficiency</dd><dd>HP:0001399, Hepatic failure - HP:0002240, Hepatomegaly</dd><dd>HP:0000938, Osteopenia - HP:0000939, Osteoporosis</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001638, Cardiomyopathy</dd><dd>HP:0200114, Metabolic alkalosis - HP:0001942, Metabolic acidosis</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003353, Propionyl-CoA carboxylase deficiency</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0001987, Hyperammonemia</dd><dd>HP:0001873, Thrombocytopenia - HP:0001873, Thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate - HP:0001942, Metabolic acidosis</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0003353, Propionyl-CoA carboxylase deficiency</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0003353, Propionyl-CoA carboxylase deficiency</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0002240, Hepatomegaly</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001875, Neutropenia</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001508, Failure to thrive</dd></dl><dl><dt>Proximity score 0.507 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ACSS2%0DPCCB&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to PCCB</a> and phenotypic similarity 0.208 to mouse mutant of PCCB.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0001914, hemorrhage</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0003054, spina bifida</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.631</b>
+                                    <data>(p=5.5E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.507</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.932</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>20-34926200-G-A [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs767041380">rs767041380</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PP3]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=2439172%5Balleleid%5D">(criteria provided, single submitter)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.932</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000360596.7">ACSS2:ENST00000360596.7:c.1822G&gt;A:p.(Gly608Ser)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.93637544</dd>
+                                    
+                                    <dd>REVEL: 0.708</dd>
+                                    <dd>MVP: 0.936</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>TOPMed: 0.0015%</dd>
+                                    <dd>ExAC SAS: 0.0182%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0365%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0130%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="THAP11" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000168286">THAP11</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.616</b>
+                    <data>(p=6.1E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.576</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.847</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.576 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=THAP11">THAP11</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0002874, decreased hemoglobin content</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function - MP:0005584, abnormal enzyme/coenzyme activity</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0005584, abnormal enzyme/coenzyme activity</dd><dd>HP:0001399, Hepatic failure - MP:0005584, abnormal enzyme/coenzyme activity</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0010499, abnormal ventricle myocardium morphology</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002874, decreased hemoglobin content</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0002874, decreased hemoglobin content</dd><dd>HP:0001873, Thrombocytopenia - MP:0003179, thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0005584, abnormal enzyme/coenzyme activity</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0005584, abnormal enzyme/coenzyme activity</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0002182, abnormal astrocyte morphology</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0003179, thrombocytopenia</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.207 to zebrafish mutant involving <a href="http://zfin.org/action/quicksearch/query?query=THAP11">THAP11</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - ZP:0102283, neuroblast differentiation disrupted, abnormal</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=THAP11%0DUSP53&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to USP53</a> and phenotypic similarity 0.682 to <a href="http://www.omim.org/entry/619658">Cholestasis, progressive familial intrahepatic, 7, with or without hearing loss</a> associated with USP53.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001744, Splenomegaly</dd><dd>HP:0001903, Anemia - HP:0001744, Splenomegaly</dd><dd>HP:0001541, Ascites - HP:0001744, Splenomegaly</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001744, Splenomegaly</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001744, Splenomegaly</dd><dd>HP:0001396, Cholestasis - HP:0001396, Cholestasis</dd><dd>HP:0001410, Decreased liver function - HP:0001396, Cholestasis</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0031956, Elevated circulating aspartate aminotransferase concentration</dd><dd>HP:0001399, Hepatic failure - HP:0001396, Cholestasis</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - HP:0410053, Elevated circulating gamma-aminobutyric acid concentration</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003155, Elevated circulating alkaline phosphatase concentration</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0410053, Elevated circulating gamma-aminobutyric acid concentration</dd><dd>HP:0001873, Thrombocytopenia - HP:0001744, Splenomegaly</dd><dd>HP:0002151, Increased serum lactate - HP:0410053, Elevated circulating gamma-aminobutyric acid concentration</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0031964, Elevated circulating alanine aminotransferase concentration</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0031956, Elevated circulating aspartate aminotransferase concentration</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001395, Hepatic fibrosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001744, Splenomegaly</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=THAP11%0DUSP53&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to USP53</a> and phenotypic similarity 0.519 to mouse mutant of USP53.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0010124, decreased bone mineral content</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0001399, Hepatic failure - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0000938, Osteopenia - MP:0000063, decreased bone mineral density</dd><dd>HP:0001642, Pulmonic stenosis - MP:0003896, prolonged PR interval</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005568, increased circulating total protein level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0005568, increased circulating total protein level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0005178, increased circulating cholesterol level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0005344, increased circulating bilirubin level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0004738, abnormal auditory brainstem response</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.616</b>
+                                    <data>(p=6.1E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.576</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.847</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">DISRUPTIVE_INFRAME_INSERTION</span>
+                            <b>INS</b>
+                            <b>16-67842884-G-GCAGCAGCAA [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs746671619">rs746671619</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=1926075%5Balleleid%5D">(criteria provided, single submitter)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.847</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000303596.3">THAP11:ENST00000303596.3:c.348_356dup:p.(Gln130_Gln132dup)</a>
+                                        
+                                    </dd>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000562787.6">THAP11:ENST00000562787.6:c.-492+4516_-492+4517insTTGCTGCTG:p.(=)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>gnomAD_E_AMR: 0.0060%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0296%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0019%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0033%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="PKD2L1" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000107593">PKD2L1</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.604</b>
+                    <data>(p=6.5E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.519</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.905</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Proximity score 0.519 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=PKD2L1%0DPKHD1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to PKHD1</a> and phenotypic similarity 0.727 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=53035">Caroli disease</a> associated with PKHD1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001744, Splenomegaly</dd><dd>HP:0001903, Anemia - HP:0001974, Leukocytosis</dd><dd>HP:0001541, Ascites - HP:0001541, Ascites</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001974, Leukocytosis</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001974, Leukocytosis</dd><dd>HP:0001396, Cholestasis - HP:0001396, Cholestasis</dd><dd>HP:0001410, Decreased liver function - HP:0001409, Portal hypertension</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0031964, Elevated circulating alanine aminotransferase concentration</dd><dd>HP:0001399, Hepatic failure - HP:0001409, Portal hypertension</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001409, Portal hypertension</dd><dd>HP:0200114, Metabolic alkalosis - HP:0001945, Fever</dd><dd>HP:0003073, Hypoalbuminemia - HP:0045056, Abnormal circulating alpha-fetoprotein concentration</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0045056, Abnormal circulating alpha-fetoprotein concentration</dd><dd>HP:0001873, Thrombocytopenia - HP:0001974, Leukocytosis</dd><dd>HP:0002151, Increased serum lactate - HP:0002908, Conjugated hyperbilirubinemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0031964, Elevated circulating alanine aminotransferase concentration</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0031964, Elevated circulating alanine aminotransferase concentration</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001394, Cirrhosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001974, Leukocytosis</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001824, Weight loss</dd></dl><dl><dt>Proximity score 0.519 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=PKD2L1%0DPKHD1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to PKHD1</a> and phenotypic similarity 0.548 to mouse mutant of PKHD1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0003327, liver cyst</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0003254, bile duct inflammation</dd><dd>HP:0001410, Decreased liver function - MP:0003254, bile duct inflammation</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0003254, bile duct inflammation</dd><dd>HP:0001399, Hepatic failure - MP:0003254, bile duct inflammation</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0003254, bile duct inflammation</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0003254, bile duct inflammation</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0003333, liver fibrosis</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001732, postnatal growth retardation</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.604</b>
+                                    <data>(p=6.5E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.519</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.905</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>10-100297029-A-G [0/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting, PP3]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.905</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000318222.4">PKD2L1:ENST00000318222.4:c.1136T&gt;C:p.(Leu379Pro)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.9051355</dd>
+                                    
+                                    <dd>REVEL: 0.750</dd>
+                                    <dd>MVP: 0.905</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="BUB1B" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000156970">BUB1B</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.597</b>
+                    <data>(p=6.7E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.513</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.910</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.558 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=1052">Mosaic variegated aneuploidy syndrome</a> associated with BUB1B.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0006721, Acute lymphoblastic leukemia</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - HP:0001541, Ascites</dd><dd>HP:0010972, Anemia of inadequate production - HP:0006721, Acute lymphoblastic leukemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0002797, Osteolysis</dd><dd>HP:0001396, Cholestasis - HP:0000821, Hypothyroidism</dd><dd>HP:0001410, Decreased liver function - HP:0000821, Hypothyroidism</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0000821, Hypothyroidism</dd><dd>HP:0000938, Osteopenia - HP:0002797, Osteolysis</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001682, Subvalvular aortic stenosis</dd><dd>HP:0200114, Metabolic alkalosis - HP:0010880, Increased nuchal translucency</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0010880, Increased nuchal translucency</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0000821, Hypothyroidism</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001679, Abnormal aortic morphology</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.513 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=BUB1B">BUB1B</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0010080, abnormal hepatocyte physiology</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0010080, abnormal hepatocyte physiology</dd><dd>HP:0001410, Decreased liver function - MP:0010080, abnormal hepatocyte physiology</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0010080, abnormal hepatocyte physiology</dd><dd>HP:0001399, Hepatic failure - MP:0010080, abnormal hepatocyte physiology</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0010080, abnormal hepatocyte physiology</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0010080, abnormal hepatocyte physiology</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0010080, abnormal hepatocyte physiology</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001732, postnatal growth retardation</dd></dl><dl><dt>PhenIX semantic similarity score: 1.29 (p-value: 0.893820)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/114500">OMIM:114500</a> Colorectal cancer, somatic - autosomal dominant</dd>
+<dd><a href="http://www.omim.org/entry/257300">OMIM:257300</a> Mosaic variegated aneuploidy syndrome 1 - autosomal recessive</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=1052">ORPHA:1052</a> Mosaic variegated aneuploidy syndrome - autosomal recessive</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.597</b>
+                                    <data>(p=6.7E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.513</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.910</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>15-40212581-G-T [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs2140907754">rs2140907754</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting, BP4]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.910</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000287598.11">BUB1B:ENST00000287598.11:c.2468G&gt;T:p.(Cys823Phe)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.9095185</dd>
+                                    
+                                    <dd>REVEL: 0.184</dd>
+                                    <dd>MVP: 0.910</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="ATN1" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000111676">ATN1</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.580</b>
+                    <data>(p=7.3E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.558</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.850</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.287 to <a href="http://www.omim.org/entry/618494">Congenital hypotonia, epilepsy, developmental delay, and digital anomalies</a> associated with ATN1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0003186, Inverted nipples</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - HP:0010880, Increased nuchal translucency</dd><dd>HP:0010972, Anemia of inadequate production - HP:0002126, Polymicrogyria</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia - HP:0001382, Joint hypermobility</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001629, Ventricular septal defect</dd><dd>HP:0200114, Metabolic alkalosis - HP:0010880, Increased nuchal translucency</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0010880, Increased nuchal translucency</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0002126, Polymicrogyria</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0003186, Inverted nipples</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001680, Coarctation of aorta</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.558 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=ATN1">ATN1</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0005016, decreased lymphocyte cell number</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0000266, abnormal heart morphology</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - MP:0005419, decreased circulating serum albumin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0001552, increased circulating triglyceride level</dd><dd>HP:0001873, Thrombocytopenia - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0000219, increased neutrophil cell number</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ATN1%0DBMP2&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to BMP2</a> and phenotypic similarity 0.638 to <a href="http://www.omim.org/entry/235200">HFE hemochromatosis, modifier of</a> associated with BMP2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001744, Splenomegaly</dd><dd>HP:0001903, Anemia - HP:0001744, Splenomegaly</dd><dd>HP:0001541, Ascites - HP:0001541, Ascites</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001744, Splenomegaly</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0000939, Osteoporosis</dd><dd>HP:0001396, Cholestasis - HP:0001402, Hepatocellular carcinoma</dd><dd>HP:0001410, Decreased liver function - HP:0001394, Cirrhosis</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0001399, Hepatic failure - HP:0001394, Cirrhosis</dd><dd>HP:0000938, Osteopenia - HP:0000939, Osteoporosis</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001640, Cardiomegaly</dd><dd>HP:0200114, Metabolic alkalosis - HP:0001952, Glucose intolerance</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003281, Increased circulating ferritin concentration</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003281, Increased circulating ferritin concentration</dd><dd>HP:0001873, Thrombocytopenia - HP:0001744, Splenomegaly</dd><dd>HP:0002151, Increased serum lactate - HP:0003281, Increased circulating ferritin concentration</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001394, Cirrhosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001744, Splenomegaly</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ATN1%0DBMP2&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to BMP2</a> and phenotypic similarity 0.282 to mouse mutant of BMP2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0000928, incomplete rostral neuropore closure</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001262, decreased body weight</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ATN1%0DBMP2&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to BMP2</a> and phenotypic similarity 0.302 to fish mutant of BMP2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - ZP:0009826, liver development decreased process quality, abnormal</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - ZP:0009826, liver development decreased process quality, abnormal</dd><dd>HP:0001410, Decreased liver function - ZP:0009826, liver development decreased process quality, abnormal</dd><dd>HP:0002910, Elevated hepatic transaminase - ZP:0009826, liver development decreased process quality, abnormal</dd><dd>HP:0001399, Hepatic failure - ZP:0009826, liver development decreased process quality, abnormal</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - ZP:0009826, liver development decreased process quality, abnormal</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - ZP:0009826, liver development decreased process quality, abnormal</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - ZP:0009826, liver development decreased process quality, abnormal</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.21 (p-value: 0.919700)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/125370">OMIM:125370</a> Dentatorubral-pallidoluysian atrophy - autosomal dominant</dd>
+<dd><a href="http://www.omim.org/entry/618494">OMIM:618494</a> Congenital hypotonia, epilepsy, developmental delay, and digital anomalies - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=101">ORPHA:101</a> Dentatorubral pallidoluysian atrophy - autosomal dominant</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.580</b>
+                                    <data>(p=7.3E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.558</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.850</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.287 to OMIM:618494 Congenital hypotonia, epilepsy, developmental delay, and digital anomalies</dt>
+                                
+                                    <dt>Phenotypic similarity 0.138 to ORPHA:101 Dentatorubral pallidoluysian atrophy</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">DISRUPTIVE_INFRAME_DELETION</span>
+                            <b>DEL</b>
+                            <b>12-6936728-ACAGCAGCAGCAGCAG-A [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs60216939">rs60216939</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=1038180%5Balleleid%5D">(criteria provided, single submitter)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.850</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000396684.3">ATN1:ENST00000396684.3:c.1494_1508del:p.(Gln498_Gln502del)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="PITX3" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000107859">PITX3</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.574</b>
+                    <data>(p=7.5E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.662</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.730</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.662 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=PITX3">PITX3</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0002628, hepatic steatosis</dd><dd>HP:0001903, Anemia - MP:0003179, thrombocytopenia</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0000322, increased granulocyte number</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0000221, decreased leukocyte cell number</dd><dd>HP:0001396, Cholestasis - MP:0002628, hepatic steatosis</dd><dd>HP:0001410, Decreased liver function - MP:0002628, hepatic steatosis</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0002628, hepatic steatosis</dd><dd>HP:0001399, Hepatic failure - MP:0002628, hepatic steatosis</dd><dd>HP:0000938, Osteopenia - MP:0004016, decreased bone mass</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0008805, decreased circulating amylase level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0005179, decreased circulating cholesterol level</dd><dd>HP:0001873, Thrombocytopenia - MP:0003179, thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0002628, hepatic steatosis</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0002628, hepatic steatosis</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0011448, decreased dopaminergic neuron number</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0002628, hepatic steatosis</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0000322, increased granulocyte number</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001262, decreased body weight</dd></dl><dl><dt>Proximity score 0.501 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=PITX3%0DMYB&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to MYB</a> and phenotypic similarity 0.628 to mouse mutant of MYB.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000691, enlarged spleen</dd><dd>HP:0001903, Anemia - MP:0001577, anemia</dd><dd>HP:0001541, Ascites - MP:0000691, enlarged spleen</dd><dd>HP:0010972, Anemia of inadequate production - MP:0000245, abnormal erythropoiesis</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0002417, abnormal megakaryocyte morphology</dd><dd>HP:0001396, Cholestasis - MP:0000689, abnormal spleen morphology</dd><dd>HP:0001410, Decreased liver function - MP:0000689, abnormal spleen morphology</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000689, abnormal spleen morphology</dd><dd>HP:0001399, Hepatic failure - MP:0000689, abnormal spleen morphology</dd><dd>HP:0000938, Osteopenia - MP:0002417, abnormal megakaryocyte morphology</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - MP:0005505, thrombocytosis</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000689, abnormal spleen morphology</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000689, abnormal spleen morphology</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000689, abnormal spleen morphology</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0000222, decreased neutrophil cell number</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.501 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=PITX3%0DMYB&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to MYB</a> and phenotypic similarity 0.424 to fish mutant of MYB.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - ZP:0018768, thymus absent, abnormal</dd><dd>HP:0001903, Anemia - ZP:0000547, definitive hemopoiesis disrupted, abnormal</dd><dd>HP:0001541, Ascites - ZP:0001192, heart edematous, abnormal</dd><dd>HP:0010972, Anemia of inadequate production - ZP:0000547, definitive hemopoiesis disrupted, abnormal</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - ZP:0018782, neutrophil differentiation decreased occurrence, abnormal</dd><dd>HP:0001396, Cholestasis - ZP:0018768, thymus absent, abnormal</dd><dd>HP:0001410, Decreased liver function - ZP:0018768, thymus absent, abnormal</dd><dd>HP:0002910, Elevated hepatic transaminase - ZP:0018768, thymus absent, abnormal</dd><dd>HP:0001399, Hepatic failure - ZP:0018768, thymus absent, abnormal</dd><dd>HP:0000938, Osteopenia - ZP:0010649, ossification involved in bone maturation arrested, abnormal</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - ZP:0000547, definitive hemopoiesis disrupted, abnormal</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - ZP:0018768, thymus absent, abnormal</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - ZP:0018768, thymus absent, abnormal</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - ZP:0018768, thymus absent, abnormal</dd><dd>HP:0004333, Bone-marrow foam cells - ZP:0018782, neutrophil differentiation decreased occurrence, abnormal</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.01 (p-value: 0.821160)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/107250">OMIM:107250</a> Anterior segment dysgenesis 1, multiple subtypes - autosomal dominant</dd>
+<dd><a href="http://www.omim.org/entry/610623">OMIM:610623</a> Cataract 11, multiple types - autosomal dominant/recessive</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.574</b>
+                                    <data>(p=7.5E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.662</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.730</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>10-102231979-C-G [0/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.730</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000370002.8">PITX3:ENST00000370002.8:c.102G&gt;C:p.(Lys34Asn)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.73019105</dd>
+                                    
+                                    <dd>REVEL: 0.361</dd>
+                                    <dd>MVP: 0.730</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="KCNH6" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000173826">KCNH6</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.572</b>
+                    <data>(p=7.5E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.912</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.386 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=KCNH6">KCNH6</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0009176, increased pancreatic alpha cell number</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0009176, increased pancreatic alpha cell number</dd><dd>HP:0001410, Decreased liver function - MP:0003339, decreased pancreatic beta cell number</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0003339, decreased pancreatic beta cell number</dd><dd>HP:0001399, Hepatic failure - MP:0003339, decreased pancreatic beta cell number</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0002079, increased circulating insulin level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002079, increased circulating insulin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0002727, decreased circulating insulin level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0002079, increased circulating insulin level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0003339, decreased pancreatic beta cell number</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0003339, decreased pancreatic beta cell number</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0003564, abnormal insulin secretion</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.188 to zebrafish mutant involving <a href="http://zfin.org/action/quicksearch/query?query=KCNH6">KCNH6</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - ZP:0000038, pericardium edematous, abnormal</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - ZP:0005691, dorsal aorta decreased diameter, abnormal</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=KCNH6%0DKCNE2&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to KCNE2</a> and phenotypic similarity 0.227 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=101016">Romano-Ward syndrome</a> associated with KCNE2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001279, Syncope</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - HP:0002900, Hypokalemia</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0002900, Hypokalemia</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0002900, Hypokalemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0012332, Abnormal autonomic nervous system physiology</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=KCNH6%0DKCNE2&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to KCNE2</a> and phenotypic similarity 0.684 to mouse mutant of KCNE2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0008808, decreased spleen iron level</dd><dd>HP:0001903, Anemia - MP:0001577, anemia</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0008388, hypochromic microcytic anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0008388, hypochromic microcytic anemia</dd><dd>HP:0001396, Cholestasis - MP:0008006, increased stomach pH</dd><dd>HP:0001410, Decreased liver function - MP:0008006, increased stomach pH</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0008006, increased stomach pH</dd><dd>HP:0001399, Hepatic failure - MP:0008006, increased stomach pH</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0011285, increased circulating erythropoietin level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0011891, decreased circulating ferritin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0011891, decreased circulating ferritin level</dd><dd>HP:0001873, Thrombocytopenia - MP:0005505, thrombocytosis</dd><dd>HP:0002151, Increased serum lactate - MP:0011285, increased circulating erythropoietin level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0008006, increased stomach pH</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0008006, increased stomach pH</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0004139, abnormal gastric parietal cell morphology</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0001577, anemia</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.572</b>
+                                    <data>(p=7.5E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.912</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>17-63542258-G-T [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs764823797">rs764823797</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PP3_Moderate]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=2283744%5Balleleid%5D">(criteria provided, single submitter)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.912</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000314672.10">KCNH6:ENST00000314672.10:c.1972G&gt;T:p.(Gly658Trp)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.9149335</dd>
+                                    
+                                    <dd>REVEL: 0.899</dd>
+                                    <dd>MVP: 0.915</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>TOPMed: 0.0004%</dd>
+                                    <dd>ExAC SAS: 0.0182%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0058%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0227%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="ANXA5" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000164111">ANXA5</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.572</b>
+                    <data>(p=7.5E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.506</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.905</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Proximity score 0.506 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ANXA5%0DPKD1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to PKD1</a> and phenotypic similarity 0.362 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=730">Autosomal dominant polycystic kidney disease</a> associated with PKD1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001407, Hepatic cysts</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0001407, Hepatic cysts</dd><dd>HP:0001410, Decreased liver function - HP:0001407, Hepatic cysts</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0001407, Hepatic cysts</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001634, Mitral valve prolapse</dd><dd>HP:0200114, Metabolic alkalosis - HP:0003259, Elevated circulating creatinine concentration</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003259, Elevated circulating creatinine concentration</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003259, Elevated circulating creatinine concentration</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0003259, Elevated circulating creatinine concentration</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001407, Hepatic cysts</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0011004, Abnormal systemic arterial morphology</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.506 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ANXA5%0DPKD1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to PKD1</a> and phenotypic similarity 0.712 to mouse mutant of PKD1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0003327, liver cyst</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0002928, abnormal bile duct morphology</dd><dd>HP:0001410, Decreased liver function - MP:0003325, decreased liver function</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0003325, decreased liver function</dd><dd>HP:0001399, Hepatic failure - MP:0003325, decreased liver function</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005328, abnormal circulating creatinine level</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0005328, abnormal circulating creatinine level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0003325, decreased liver function</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0003325, decreased liver function</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000608, dissociated hepatocytes</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.506 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ANXA5%0DPKD1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to PKD1</a> and phenotypic similarity 0.301 to fish mutant of PKD1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - ZP:0006450, liver cystic, abnormal</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - ZP:0001192, heart edematous, abnormal</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - ZP:0006450, liver cystic, abnormal</dd><dd>HP:0001410, Decreased liver function - ZP:0006450, liver cystic, abnormal</dd><dd>HP:0002910, Elevated hepatic transaminase - ZP:0006450, liver cystic, abnormal</dd><dd>HP:0001399, Hepatic failure - ZP:0006450, liver cystic, abnormal</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - ZP:0006450, liver cystic, abnormal</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - ZP:0006450, liver cystic, abnormal</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - ZP:0006450, liver cystic, abnormal</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/614391">OMIM:614391</a> Pregnancy loss, recurrent, susceptibility to, 3 (susceptibility)</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.572</b>
+                                    <data>(p=7.5E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.506</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.905</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>4-121678449-C-T [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs368943069">rs368943069</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.905</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000296511.10">ANXA5:ENST00000296511.10:c.440G&gt;A:p.(Gly147Glu)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.90547425</dd>
+                                    
+                                    <dd>REVEL: 0.490</dd>
+                                    <dd>MVP: 0.905</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="ACVR2A" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000121989">ACVR2A</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.549</b>
+                    <data>(p=8.3E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.503</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.899</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.345 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=ACVR2A">ACVR2A</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0005012, decreased eosinophil cell number</dd><dd>HP:0001903, Anemia - MP:0000222, decreased neutrophil cell number</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0005012, decreased eosinophil cell number</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0005012, decreased eosinophil cell number</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - MP:0000222, decreased neutrophil cell number</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0000222, decreased neutrophil cell number</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.143 to zebrafish mutant involving <a href="http://zfin.org/action/quicksearch/query?query=ACVR2A">ACVR2A</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - ZP:0009676, maxilla fused with maxilla, abnormal</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia - ZP:0009676, maxilla fused with maxilla, abnormal</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.503 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ACVR2A%0DBMP6&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to BMP6</a> and phenotypic similarity 0.618 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=465508">Symptomatic form of HFE-related hemochromatosis</a> associated with BMP6.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001744, Splenomegaly</dd><dd>HP:0001903, Anemia - HP:0001744, Splenomegaly</dd><dd>HP:0001541, Ascites - HP:0001386, Joint swelling</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001744, Splenomegaly</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0000939, Osteoporosis</dd><dd>HP:0001396, Cholestasis - HP:0030153, Cholangiocarcinoma</dd><dd>HP:0001410, Decreased liver function - HP:0100626, Chronic hepatic failure</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0100626, Chronic hepatic failure</dd><dd>HP:0000938, Osteopenia - HP:0000939, Osteoporosis</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001640, Cardiomegaly</dd><dd>HP:0200114, Metabolic alkalosis - HP:0003074, Hyperglycemia</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003281, Increased circulating ferritin concentration</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0040171, Decreased serum testosterone concentration</dd><dd>HP:0001873, Thrombocytopenia - HP:0001744, Splenomegaly</dd><dd>HP:0002151, Increased serum lactate - HP:0003074, Hyperglycemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0009830, Peripheral neuropathy</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001394, Cirrhosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001744, Splenomegaly</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001824, Weight loss</dd></dl><dl><dt>Proximity score 0.503 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ACVR2A%0DBMP6&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to BMP6</a> and phenotypic similarity 0.483 to mouse mutant of BMP6.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000613, abnormal salivary gland morphology</dd><dd>HP:0001903, Anemia - MP:0005641, increased mean corpuscular hemoglobin concentration</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0005561, increased mean corpuscular hemoglobin</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0000613, abnormal salivary gland morphology</dd><dd>HP:0001410, Decreased liver function - MP:0000613, abnormal salivary gland morphology</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000613, abnormal salivary gland morphology</dd><dd>HP:0001399, Hepatic failure - MP:0000613, abnormal salivary gland morphology</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0005333, decreased heart rate</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005343, increased circulating aspartate transaminase level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002941, increased circulating alanine transaminase level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0002941, increased circulating alanine transaminase level</dd><dd>HP:0001873, Thrombocytopenia - MP:0005641, increased mean corpuscular hemoglobin concentration</dd><dd>HP:0002151, Increased serum lactate - MP:0005343, increased circulating aspartate transaminase level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000613, abnormal salivary gland morphology</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000613, abnormal salivary gland morphology</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0002152, abnormal brain morphology</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000613, abnormal salivary gland morphology</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0005641, increased mean corpuscular hemoglobin concentration</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001262, decreased body weight</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.549</b>
+                                    <data>(p=8.3E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.503</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.899</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>2-147927261-A-T [0/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.899</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000241416.12">ACVR2A:ENST00000241416.12:c.1529A&gt;T:p.(Glu510Val)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.8990258</dd>
+                                    
+                                    <dd>REVEL: 0.526</dd>
+                                    <dd>MVP: 0.899</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="MME" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000196549">MME</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.541</b>
+                    <data>(p=8.5E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.510</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.888</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.232 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=497764">Spinocerebellar ataxia type 43</a> associated with MME.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - HP:0003387, Decreased number of large peripheral myelinated nerve fibers</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0003387, Decreased number of large peripheral myelinated nerve fibers</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.424 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=MME">MME</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0005151, diffuse hepatic necrosis</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0005151, diffuse hepatic necrosis</dd><dd>HP:0001410, Decreased liver function - MP:0005151, diffuse hepatic necrosis</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0005151, diffuse hepatic necrosis</dd><dd>HP:0001399, Hepatic failure - MP:0005151, diffuse hepatic necrosis</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - MP:0005416, abnormal circulating protein level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0005416, abnormal circulating protein level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0005151, diffuse hepatic necrosis</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0005151, diffuse hepatic necrosis</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0005404, abnormal axon morphology</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0005151, diffuse hepatic necrosis</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.510 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=MME%0DCR2&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to CR2</a> and phenotypic similarity 0.667 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=1572">Common variable immunodeficiency</a> associated with CR2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001744, Splenomegaly</dd><dd>HP:0001903, Anemia - HP:0001878, Hemolytic anemia</dd><dd>HP:0001541, Ascites - HP:0001744, Splenomegaly</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001878, Hemolytic anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001888, Lymphopenia</dd><dd>HP:0001396, Cholestasis - HP:0001392, Abnormality of the liver</dd><dd>HP:0001410, Decreased liver function - HP:0001392, Abnormality of the liver</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0001399, Hepatic failure - HP:0001392, Abnormality of the liver</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0000979, Purpura</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - HP:0001973, Autoimmune thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001392, Abnormality of the liver</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001888, Lymphopenia</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001531, Failure to thrive in infancy</dd></dl><dl><dt>Proximity score 0.510 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=MME%0DCR2&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to CR2</a> and phenotypic similarity 0.362 to mouse mutant of CR2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0002359, abnormal spleen germinal center morphology</dd><dd>HP:0001903, Anemia - MP:0000222, decreased neutrophil cell number</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0004940, abnormal B-1 B cell morphology</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0004940, abnormal B-1 B cell morphology</dd><dd>HP:0001396, Cholestasis - MP:0002359, abnormal spleen germinal center morphology</dd><dd>HP:0001410, Decreased liver function - MP:0002359, abnormal spleen germinal center morphology</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0002359, abnormal spleen germinal center morphology</dd><dd>HP:0001399, Hepatic failure - MP:0002359, abnormal spleen germinal center morphology</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - MP:0000222, decreased neutrophil cell number</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0002359, abnormal spleen germinal center morphology</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0002359, abnormal spleen germinal center morphology</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0002359, abnormal spleen germinal center morphology</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0000222, decreased neutrophil cell number</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.13 (p-value: 0.999760)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/617017">OMIM:617017</a> Charcot-Marie-Tooth disease, axonal, type 2T - autosomal dominant/recessive</dd>
+<dd><a href="http://www.omim.org/entry/617018">OMIM:617018</a> ?Spinocerebellar ataxia 43 (unconfirmed)</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=497764">ORPHA:497764</a> Spinocerebellar ataxia type 43 - autosomal dominant/recessive</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.541</b>
+                                    <data>(p=8.5E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.510</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.888</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.232 to ORPHA:497764 Spinocerebellar ataxia type 43</dt>
+                                
+                                    <dt>Phenotypic similarity 0.183 to OMIM:617018 ?Spinocerebellar ataxia 43</dt>
+                                
+                                    <dt>Phenotypic similarity 0.183 to OMIM:617017 Charcot-Marie-Tooth disease, axonal, type 2T</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>3-155116718-A-G [0/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.888</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000360490.7">MME:ENST00000360490.7:c.494A&gt;G:p.(Tyr165Cys)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.8877893</dd>
+                                    
+                                    <dd>REVEL: 0.514</dd>
+                                    <dd>MVP: 0.888</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="SLC7A10" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000130876">SLC7A10</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.538</b>
+                    <data>(p=8.6E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.502</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.895</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.265 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=SLC7A10">SLC7A10</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001262, decreased body weight</dd></dl><dl><dt>Proximity score 0.502 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=SLC7A10%0DSLC7A7&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SLC7A7</a> and phenotypic similarity 0.789 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=470">Lysinuric protein intolerance</a> associated with SLC7A7.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0001903, Anemia - HP:0001903, Anemia</dd><dd>HP:0001541, Ascites - HP:0002240, Hepatomegaly</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001903, Anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0031020, Bone marrow hypercellularity</dd><dd>HP:0001396, Cholestasis - HP:0001399, Hepatic failure</dd><dd>HP:0001410, Decreased liver function - HP:0001399, Hepatic failure</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0001399, Hepatic failure - HP:0001399, Hepatic failure</dd><dd>HP:0000938, Osteopenia - HP:0000938, Osteopenia</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001627, Abnormal heart morphology</dd><dd>HP:0200114, Metabolic alkalosis - HP:0001987, Hyperammonemia</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003281, Increased circulating ferritin concentration</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003233, Decreased HDL cholesterol concentration</dd><dd>HP:0001873, Thrombocytopenia - HP:0001873, Thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate - HP:0003348, Hyperalaninemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0012280, Hepatic amyloidosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0012156, Hemophagocytosis</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001508, Failure to thrive</dd></dl><dl><dt>Proximity score 0.502 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=SLC7A10%0DSLC7A7&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SLC7A7</a> and phenotypic similarity 0.519 to mouse mutant of SLC7A7.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0004953, decreased spleen weight</dd><dd>HP:0001903, Anemia - MP:0000219, increased neutrophil cell number</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0000219, increased neutrophil cell number</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0005016, decreased lymphocyte cell number</dd><dd>HP:0001396, Cholestasis - MP:0000597, delayed hepatic development</dd><dd>HP:0001410, Decreased liver function - MP:0000597, delayed hepatic development</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000597, delayed hepatic development</dd><dd>HP:0001399, Hepatic failure - MP:0000597, delayed hepatic development</dd><dd>HP:0000938, Osteopenia - MP:0020137, decreased bone mineralization</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - MP:0000219, increased neutrophil cell number</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000597, delayed hepatic development</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000597, delayed hepatic development</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000597, delayed hepatic development</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0000219, increased neutrophil cell number</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0008489, slow postnatal weight gain</dd></dl><dl><dt>Proximity score 0.502 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=SLC7A10%0DSLC7A7&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SLC7A7</a> and phenotypic similarity 0.323 to fish mutant of SLC7A7.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - ZP:0016849, microglia development decreased occurrence, abnormal</dd><dd>HP:0001903, Anemia - ZP:0016849, microglia development decreased occurrence, abnormal</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - ZP:0016849, microglia development decreased occurrence, abnormal</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - ZP:0016849, microglia development decreased occurrence, abnormal</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - ZP:0016849, microglia development decreased occurrence, abnormal</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - ZP:0016849, microglia development decreased occurrence, abnormal</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - ZP:0016849, microglia development decreased occurrence, abnormal</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.538</b>
+                                    <data>(p=8.6E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.502</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.895</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>19-33215803-C-T [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs567938130">rs567938130</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.895</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000253188.8">SLC7A10:ENST00000253188.8:c.322G&gt;A:p.(Ala108Thr)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.9017956</dd>
+                                    
+                                    <dd>REVEL: 0.401</dd>
+                                    <dd>MVP: 0.902</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0312%</dd>
+                                    <dd>TOPMed: 0.0110%</dd>
+                                    <dd>ExAC NFE: 0.0535%</dd>
+                                    <dd>ExAC SAS: 0.0247%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0112%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0162%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0056%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0164%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.395</b>
+                                    <data>(p=1.3E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.502</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.832</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>19-33215803-C-T [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs567938130">rs567938130</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.895</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000253188.8">SLC7A10:ENST00000253188.8:c.322G&gt;A:p.(Ala108Thr)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.9017956</dd>
+                                    
+                                    <dd>REVEL: 0.401</dd>
+                                    <dd>MVP: 0.902</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0312%</dd>
+                                    <dd>TOPMed: 0.0110%</dd>
+                                    <dd>ExAC NFE: 0.0535%</dd>
+                                    <dd>ExAC SAS: 0.0247%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0112%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0162%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0056%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0164%</dd>
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SPLICE_REGION_VARIANT</span>
+                            <b>SNV</b>
+                            <b>19-33210906-T-C [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs375747229">rs375747229</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.770</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000253188.8">SLC7A10:ENST00000253188.8:c.1017-8A&gt;G:p.?</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0625%</dd>
+                                    <dd>TOPMed: 0.0068%</dd>
+                                    <dd>ExAC AFR: 0.0108%</dd>
+                                    <dd>ExAC EAS: 0.2005%</dd>
+                                    <dd>ExAC SAS: 0.0621%</dd>
+                                    <dd>gnomAD_E_EAS: 0.1803%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0184%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0455%</dd>
+                                    <dd>gnomAD_G_EAS: 0.2469%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="ZNF787" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000142409">ZNF787</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.526</b>
+                    <data>(p=9.0E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.537</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.850</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.537 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=ZNF787">ZNF787</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0002833, increased heart weight</dd><dd>HP:0001903, Anemia - MP:0003179, thrombocytopenia</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0003179, thrombocytopenia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0002833, increased heart weight</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - MP:0000186, decreased circulating HDL cholesterol level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0000186, decreased circulating HDL cholesterol level</dd><dd>HP:0001873, Thrombocytopenia - MP:0003179, thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0005293, impaired glucose tolerance</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0003179, thrombocytopenia</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.526</b>
+                                    <data>(p=9.0E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.537</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.850</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">DISRUPTIVE_INFRAME_INSERTION</span>
+                            <b>INS</b>
+                            <b>19-56088071-C-CTCG [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs5828672">rs5828672</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.850</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000610935.2">ZNF787:ENST00000610935.2:c.1098_1100dup:p.(Asp366dup)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="PDE6B" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000133256">PDE6B</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.522</b>
+                    <data>(p=9.1E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.503</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.887</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.317 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=791">Retinitis pigmentosa</a> associated with PDE6B.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0000842, Hyperinsulinemia</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0000135, Hypogonadism</dd><dd>HP:0001410, Decreased liver function - HP:0000135, Hypogonadism</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0000135, Hypogonadism</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - HP:0000842, Hyperinsulinemia</dd><dd>HP:0003073, Hypoalbuminemia - HP:0000842, Hyperinsulinemia</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0000842, Hyperinsulinemia</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0000842, Hyperinsulinemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0000648, Optic atrophy</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0005978, Type II diabetes mellitus</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001513, Obesity</dd></dl><dl><dt>Phenotypic similarity 0.460 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=PDE6B">PDE6B</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia - MP:0005641, increased mean corpuscular hemoglobin concentration</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0005641, increased mean corpuscular hemoglobin concentration</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0012311, decreased defecation amount</dd><dd>HP:0001410, Decreased liver function - MP:0012311, decreased defecation amount</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0012311, decreased defecation amount</dd><dd>HP:0001399, Hepatic failure - MP:0012311, decreased defecation amount</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005627, increased circulating potassium level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0008805, decreased circulating amylase level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0002644, decreased circulating triglyceride level</dd><dd>HP:0001873, Thrombocytopenia - MP:0005641, increased mean corpuscular hemoglobin concentration</dd><dd>HP:0002151, Increased serum lactate - MP:0005627, increased circulating potassium level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0012311, decreased defecation amount</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0012311, decreased defecation amount</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0005641, increased mean corpuscular hemoglobin concentration</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001262, decreased body weight</dd></dl><dl><dt>Proximity score 0.503 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=PDE6B%0DENTPD5&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to ENTPD5</a> and phenotypic similarity 0.690 to mouse mutant of ENTPD5.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000599, enlarged liver</dd><dd>HP:0001903, Anemia - MP:0008114, abnormal Kupffer cell morphology</dd><dd>HP:0001541, Ascites - MP:0000599, enlarged liver</dd><dd>HP:0010972, Anemia of inadequate production - MP:0008114, abnormal Kupffer cell morphology</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0008114, abnormal Kupffer cell morphology</dd><dd>HP:0001396, Cholestasis - MP:0010042, abnormal oval cell physiology</dd><dd>HP:0001410, Decreased liver function - MP:0010042, abnormal oval cell physiology</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0010042, abnormal oval cell physiology</dd><dd>HP:0001399, Hepatic failure - MP:0010042, abnormal oval cell physiology</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0005419, decreased circulating serum albumin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0003983, decreased cholesterol level</dd><dd>HP:0001873, Thrombocytopenia - MP:0008114, abnormal Kupffer cell morphology</dd><dd>HP:0002151, Increased serum lactate - MP:0005344, increased circulating bilirubin level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0010042, abnormal oval cell physiology</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0010042, abnormal oval cell physiology</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000607, abnormal hepatocyte morphology</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0008114, abnormal Kupffer cell morphology</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001262, decreased body weight</dd></dl><dl><dt>Proximity score 0.503 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=PDE6B%0DENTPD5&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to ENTPD5</a> and phenotypic similarity 0.324 to fish mutant of ENTPD5.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - ZP:0002797, bone mineralization disrupted, abnormal</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia - ZP:0002797, bone mineralization disrupted, abnormal</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - ZP:0009437, phosphate ion homeostasis disrupted, abnormal</dd><dd>HP:0003073, Hypoalbuminemia - ZP:0009437, phosphate ion homeostasis disrupted, abnormal</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - ZP:0009437, phosphate ion homeostasis disrupted, abnormal</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - ZP:0009437, phosphate ion homeostasis disrupted, abnormal</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - ZP:0009437, phosphate ion homeostasis disrupted, abnormal</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.26 (p-value: 0.997250)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/163500">OMIM:163500</a> Night blindness, congenital stationary, autosomal dominant 2 - autosomal dominant</dd>
+<dd><a href="http://www.omim.org/entry/613801">OMIM:613801</a> Retinitis pigmentosa-40 - autosomal recessive</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=215">ORPHA:215</a> Congenital stationary night blindness - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=791">ORPHA:791</a> Retinitis pigmentosa - autosomal recessive</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.522</b>
+                                    <data>(p=9.1E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.503</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.887</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>4-662556-G-A [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs369416193">rs369416193</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PP3_Moderate]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=2727786%5Balleleid%5D">(criteria provided, single submitter)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.887</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000496514.6">PDE6B:ENST00000496514.6:c.1770G&gt;A:p.(Met590Ile)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.8875141</dd>
+                                    
+                                    <dd>REVEL: 0.805</dd>
+                                    <dd>MVP: 0.888</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>gnomAD_E_AMR: 0.0030%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="CACNA1G" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000006283">CACNA1G</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.516</b>
+                    <data>(p=9.3E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.502</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.886</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.225 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=CACNA1G">CACNA1G</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0003354, astrocytosis</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0000876, Purkinje cell degeneration</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.502 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=CACNA1G%0DCACNA1D&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to CACNA1D</a> and phenotypic similarity 0.618 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=369929">Primary hyperaldosteronism-seizures-neurological abnormalities syndrome</a> associated with CACNA1D.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0008221, Adrenal hyperplasia</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0008221, Adrenal hyperplasia</dd><dd>HP:0001410, Decreased liver function - HP:0000859, Hyperaldosteronism</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0000859, Hyperaldosteronism</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001714, Ventricular hypertrophy</dd><dd>HP:0200114, Metabolic alkalosis - HP:0200114, Metabolic alkalosis</dd><dd>HP:0003073, Hypoalbuminemia - HP:0040084, Abnormal circulating renin</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0000859, Hyperaldosteronism</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0200114, Metabolic alkalosis</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0008221, Adrenal hyperplasia</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0002170, Intracranial hemorrhage</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.502 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=CACNA1G%0DCACNA1D&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to CACNA1D</a> and phenotypic similarity 0.423 to mouse mutant of CACNA1D.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0009176, increased pancreatic alpha cell number</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0009175, abnormal pancreatic beta cell differentiation</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0005215, abnormal pancreatic islet morphology</dd><dd>HP:0001410, Decreased liver function - MP:0003339, decreased pancreatic beta cell number</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0003339, decreased pancreatic beta cell number</dd><dd>HP:0001399, Hepatic failure - MP:0003339, decreased pancreatic beta cell number</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0004231, abnormal calcium ion homeostasis</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002727, decreased circulating insulin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0002727, decreased circulating insulin level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0004231, abnormal calcium ion homeostasis</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0003339, decreased pancreatic beta cell number</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0003339, decreased pancreatic beta cell number</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0004434, abnormal cochlear outer hair cell physiology</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0009175, abnormal pancreatic beta cell differentiation</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001262, decreased body weight</dd></dl><dl><dt>Proximity score 0.502 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=CACNA1G%0DCACNA1D&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to CACNA1D</a> and phenotypic similarity 0.192 to fish mutant of CACNA1D.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - ZP:0011236, ribbon synapse neuromast hair cell morphology, abnormal</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.47 (p-value: 0.999670)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/616795">OMIM:616795</a> Spinocerebellar ataxia 42 - autosomal dominant</dd>
+<dd><a href="http://www.omim.org/entry/618087">OMIM:618087</a> Spinocerebellar ataxia 42, early-onset, severe, with neurodevelopmental deficits - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=458803">ORPHA:458803</a> Spinocerebellar ataxia type 42 - autosomal dominant</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.516</b>
+                                    <data>(p=9.3E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.502</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.886</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>17-50578553-T-C [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs1199012971">rs1199012971</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PP3]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.886</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000359106.10">CACNA1G:ENST00000359106.10:c.2290T&gt;C:p.(Tyr764His)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.8858178</dd>
+                                    
+                                    <dd>REVEL: 0.695</dd>
+                                    <dd>MVP: 0.886</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>gnomAD_E_NFE: 0.0011%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="SLC7A11" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000151012">SLC7A11</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.512</b>
+                    <data>(p=9.5E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.503</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.883</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.318 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=SLC7A11">SLC7A11</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia - MP:0004725, decreased platelet serotonin level</dd><dd>HP:0001541, Ascites - MP:0005606, increased bleeding time</dd><dd>HP:0010972, Anemia of inadequate production - MP:0004725, decreased platelet serotonin level</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0005606, increased bleeding time</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - MP:0004725, decreased platelet serotonin level</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0004725, decreased platelet serotonin level</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.503 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=SLC7A11%0DTNFSF11&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to TNFSF11</a> and phenotypic similarity 0.548 to <a href="http://www.omim.org/entry/259710">Osteopetrosis, autosomal recessive 2</a> associated with TNFSF11.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0001903, Anemia - HP:0001903, Anemia</dd><dd>HP:0001541, Ascites - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001978, Extramedullary hematopoiesis</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001876, Pancytopenia</dd><dd>HP:0001396, Cholestasis - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0001410, Decreased liver function - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0000938, Osteopenia - HP:0011002, Osteopetrosis</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - HP:0001873, Thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0001293, Cranial nerve compression</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001876, Pancytopenia</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.503 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=SLC7A11%0DTNFSF11&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to TNFSF11</a> and phenotypic similarity 0.690 to mouse mutant of TNFSF11.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0004952, increased spleen weight</dd><dd>HP:0001903, Anemia - MP:0002811, macrocytic anemia</dd><dd>HP:0001541, Ascites - MP:0010249, lactation failure</dd><dd>HP:0010972, Anemia of inadequate production - MP:0002811, macrocytic anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0004985, decreased osteoclast cell number</dd><dd>HP:0001396, Cholestasis - MP:0001823, thymus hypoplasia</dd><dd>HP:0001410, Decreased liver function - MP:0010249, lactation failure</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0010249, lactation failure</dd><dd>HP:0001399, Hepatic failure - MP:0010249, lactation failure</dd><dd>HP:0000938, Osteopenia - MP:0000062, increased bone mineral density</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - MP:0004985, decreased osteoclast cell number</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0010249, lactation failure</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0010249, lactation failure</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0001823, thymus hypoplasia</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0004985, decreased osteoclast cell number</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001732, postnatal growth retardation</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.512</b>
+                                    <data>(p=9.5E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.503</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.883</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>4-138214610-T-C [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs35186416">rs35186416</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PP3_Moderate]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.883</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000280612.9">SLC7A11:ENST00000280612.9:c.766A&gt;G:p.(Thr256Ala)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.883</dd>
+                                    
+                                    <dd>REVEL: 0.883</dd>
+                                    <dd>MVP: 0.881</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>TOPMed: 0.0004%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="ITPR1" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000150995">ITPR1</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.501</b>
+                    <data>(p=9.8E-2)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.507</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.874</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.168 to <a href="http://www.omim.org/entry/206700">Gillespie syndrome</a> associated with ITPR1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001660, Truncus arteriosus</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.254 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=ITPR1">ITPR1</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0003059, decreased insulin secretion</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0003059, decreased insulin secretion</dd><dd>HP:0001410, Decreased liver function - MP:0003059, decreased insulin secretion</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0003059, decreased insulin secretion</dd><dd>HP:0001399, Hepatic failure - MP:0003059, decreased insulin secretion</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0003059, decreased insulin secretion</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0003059, decreased insulin secretion</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0003059, decreased insulin secretion</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.507 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ITPR1%0DSTIM1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to STIM1</a> and phenotypic similarity 0.546 to <a href="http://www.omim.org/entry/185070">Stormorken syndrome</a> associated with STIM1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0006270, Hypoplastic spleen</dd><dd>HP:0001903, Anemia - HP:0001903, Anemia</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001903, Anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001903, Anemia</dd><dd>HP:0001396, Cholestasis - HP:0001746, Asplenia</dd><dd>HP:0001410, Decreased liver function - HP:0001746, Asplenia</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0025435, Increased circulating lactate dehydrogenase concentration</dd><dd>HP:0001399, Hepatic failure - HP:0001746, Asplenia</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001892, Abnormal bleeding</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003236, Elevated circulating creatine kinase concentration</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003236, Elevated circulating creatine kinase concentration</dd><dd>HP:0001873, Thrombocytopenia - HP:0001873, Thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate - HP:0003236, Elevated circulating creatine kinase concentration</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0025435, Increased circulating lactate dehydrogenase concentration</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0025435, Increased circulating lactate dehydrogenase concentration</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001746, Asplenia</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001903, Anemia</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.507 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ITPR1%0DSTIM1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to STIM1</a> and phenotypic similarity 0.630 to mouse mutant of STIM1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000691, enlarged spleen</dd><dd>HP:0001903, Anemia - MP:0003179, thrombocytopenia</dd><dd>HP:0001541, Ascites - MP:0005048, abnormal thrombosis</dd><dd>HP:0010972, Anemia of inadequate production - MP:0000228, abnormal thrombopoiesis</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0011747, myelofibrosis</dd><dd>HP:0001396, Cholestasis - MP:0008476, increased spleen red pulp amount</dd><dd>HP:0001410, Decreased liver function - MP:0008476, increased spleen red pulp amount</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0008476, increased spleen red pulp amount</dd><dd>HP:0001399, Hepatic failure - MP:0008476, increased spleen red pulp amount</dd><dd>HP:0000938, Osteopenia - MP:0002397, abnormal bone marrow morphology</dd><dd>HP:0001642, Pulmonic stenosis - MP:0005606, increased bleeding time</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - MP:0003179, thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0008476, increased spleen red pulp amount</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0008476, increased spleen red pulp amount</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0008476, increased spleen red pulp amount</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0011747, myelofibrosis</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.507 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ITPR1%0DSTIM1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to STIM1</a> and phenotypic similarity 0.182 to fish mutant of STIM1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - ZP:0138468, CaP motoneuron decreased occurrence axon guidance, abnormal</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - ZP:0138469, CaP motoneuron arrested axon extension involved in axon guidance, abnormal</dd></dl><dl><dt>PhenIX semantic similarity score: 0.09 (p-value: 0.999560)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/117360">OMIM:117360</a> Spinocerebellar ataxia 29, congenital nonprogressive - autosomal dominant</dd>
+<dd><a href="http://www.omim.org/entry/206700">OMIM:206700</a> Gillespie syndrome - autosomal dominant/recessive</dd>
+<dd><a href="http://www.omim.org/entry/606658">OMIM:606658</a> Spinocerebellar ataxia 15 - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=1065">ORPHA:1065</a> Aniridia-cerebellar ataxia-intellectual disability syndrome - autosomal dominant/recessive</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=208513">ORPHA:208513</a> Spinocerebellar ataxia type 29 - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=98769">ORPHA:98769</a> Spinocerebellar ataxia type 15/16 - autosomal dominant</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.501</b>
+                                    <data>(p=9.8E-2)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.507</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.874</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.168 to OMIM:206700 Gillespie syndrome</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>3-4669692-A-G [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs1389594446">rs1389594446</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.874</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000649015.2">ITPR1:ENST00000649015.2:c.1925A&gt;G:p.(Asn642Ser)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.87393194</dd>
+                                    
+                                    <dd>REVEL: 0.427</dd>
+                                    <dd>MVP: 0.874</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>gnomAD_E_NFE: 0.0009%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="TMPRSS9" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000178297">TMPRSS9</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.489</b>
+                    <data>(p=1.0E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.876</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.213 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=TMPRSS9">TMPRSS9</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001260, increased body weight</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=TMPRSS9%0DSLC25A13&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SLC25A13</a> and phenotypic similarity 0.769 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=247598">Neonatal intrahepatic cholestasis due to citrin deficiency</a> associated with SLC25A13.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0001903, Anemia - HP:0001903, Anemia</dd><dd>HP:0001541, Ascites - HP:0002240, Hepatomegaly</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001903, Anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001903, Anemia</dd><dd>HP:0001396, Cholestasis - HP:0001396, Cholestasis</dd><dd>HP:0001410, Decreased liver function - HP:0001396, Cholestasis</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0001399, Hepatic failure - HP:0001396, Cholestasis</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001892, Abnormal bleeding</dd><dd>HP:0200114, Metabolic alkalosis - HP:0001987, Hyperammonemia</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003073, Hypoalbuminemia</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003233, Decreased HDL cholesterol concentration</dd><dd>HP:0001873, Thrombocytopenia - HP:0001903, Anemia</dd><dd>HP:0002151, Increased serum lactate - HP:0003128, Lactic acidosis</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001397, Hepatic steatosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001903, Anemia</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001531, Failure to thrive in infancy</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=TMPRSS9%0DSLC25A13&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SLC25A13</a> and phenotypic similarity 0.461 to mouse mutant of SLC25A13.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0002628, hepatic steatosis</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0009355, increased liver triglyceride level</dd><dd>HP:0001410, Decreased liver function - MP:0009355, increased liver triglyceride level</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0009355, increased liver triglyceride level</dd><dd>HP:0001399, Hepatic failure - MP:0009355, increased liver triglyceride level</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002727, decreased circulating insulin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0002727, decreased circulating insulin level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0009355, increased liver triglyceride level</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0009355, increased liver triglyceride level</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0002628, hepatic steatosis</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.489</b>
+                                    <data>(p=1.0E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.876</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>19-2425144-G-A [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs536020211">rs536020211</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.876</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000696167.1">TMPRSS9:ENST00000696167.1:c.2860G&gt;A:p.(Glu954Lys)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.885597</dd>
+                                    
+                                    <dd>REVEL: 0.636</dd>
+                                    <dd>MVP: 0.886</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0625%</dd>
+                                    <dd>TOPMed: 0.0625%</dd>
+                                    <dd>ExAC EAS: 0.0773%</dd>
+                                    <dd>ExAC SAS: 0.0091%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0248%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0105%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="MTOR" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000198793">MTOR</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.486</b>
+                    <data>(p=1.0E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.509</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.865</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.477 to <a href="http://www.omim.org/entry/616638">Smith-Kingsmore syndrome</a> associated with MTOR.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001873, Thrombocytopenia</dd><dd>HP:0001903, Anemia - HP:0001873, Thrombocytopenia</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001873, Thrombocytopenia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001873, Thrombocytopenia</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - HP:0001943, Hypoglycemia</dd><dd>HP:0003073, Hypoalbuminemia - HP:0001943, Hypoglycemia</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0001943, Hypoglycemia</dd><dd>HP:0001873, Thrombocytopenia - HP:0001873, Thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate - HP:0001943, Hypoglycemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0012650, Perisylvian polymicrogyria</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001943, Hypoglycemia</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001873, Thrombocytopenia</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001520, Large for gestational age</dd></dl><dl><dt>Phenotypic similarity 0.460 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=MTOR">MTOR</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia - MP:0005561, increased mean corpuscular hemoglobin</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0005561, increased mean corpuscular hemoglobin</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - MP:0005561, increased mean corpuscular hemoglobin</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0000183, decreased circulating LDL cholesterol level</dd><dd>HP:0001873, Thrombocytopenia - MP:0005561, increased mean corpuscular hemoglobin</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0005561, increased mean corpuscular hemoglobin</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.394 to zebrafish mutant involving <a href="http://zfin.org/action/quicksearch/query?query=MTOR">MTOR</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - ZP:0000720, liver decreased size, abnormal</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - ZP:0015598, liver low brightness, abnormal</dd><dd>HP:0001410, Decreased liver function - ZP:0015598, liver low brightness, abnormal</dd><dd>HP:0002910, Elevated hepatic transaminase - ZP:0015598, liver low brightness, abnormal</dd><dd>HP:0001399, Hepatic failure - ZP:0015598, liver low brightness, abnormal</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - ZP:0021359, whole organism decreased occurrence cholesterol biosynthetic process, abnormal</dd><dd>HP:0003073, Hypoalbuminemia - ZP:0021359, whole organism decreased occurrence cholesterol biosynthetic process, abnormal</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - ZP:0021359, whole organism decreased occurrence cholesterol biosynthetic process, abnormal</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - ZP:0021359, whole organism decreased occurrence cholesterol biosynthetic process, abnormal</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - ZP:0015598, liver low brightness, abnormal</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - ZP:0015598, liver low brightness, abnormal</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - ZP:0021361, myelin sheath spinal cord decreased thickness, abnormal</dd><dd>HP:0006568, Increased hepatic glycogen content - ZP:0000720, liver decreased size, abnormal</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.509 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=MTOR%0DMEFV&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to MEFV</a> and phenotypic similarity 0.588 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=342">Familial Mediterranean fever</a> associated with MEFV.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001744, Splenomegaly</dd><dd>HP:0001903, Anemia - HP:0002716, Lymphadenopathy</dd><dd>HP:0001541, Ascites - HP:0001541, Ascites</dd><dd>HP:0010972, Anemia of inadequate production - HP:0002716, Lymphadenopathy</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0002716, Lymphadenopathy</dd><dd>HP:0001396, Cholestasis - HP:0006554, Acute hepatic failure</dd><dd>HP:0001410, Decreased liver function - HP:0006554, Acute hepatic failure</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0006554, Acute hepatic failure</dd><dd>HP:0000938, Osteopenia - HP:0001369, Arthritis</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001658, Myocardial infarction</dd><dd>HP:0200114, Metabolic alkalosis - HP:0001945, Fever</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - HP:0002716, Lymphadenopathy</dd><dd>HP:0002151, Increased serum lactate - HP:0001945, Fever</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0006554, Acute hepatic failure</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0002633, Vasculitis</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.509 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=MTOR%0DMEFV&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to MEFV</a> and phenotypic similarity 0.616 to mouse mutant of MEFV.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000691, enlarged spleen</dd><dd>HP:0001903, Anemia - MP:0001577, anemia</dd><dd>HP:0001541, Ascites - MP:0000691, enlarged spleen</dd><dd>HP:0010972, Anemia of inadequate production - MP:0001577, anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0000218, increased leukocyte cell number</dd><dd>HP:0001396, Cholestasis - MP:0001860, liver inflammation</dd><dd>HP:0001410, Decreased liver function - MP:0001860, liver inflammation</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0001860, liver inflammation</dd><dd>HP:0001399, Hepatic failure - MP:0001860, liver inflammation</dd><dd>HP:0000938, Osteopenia - MP:0002933, joint inflammation</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0008553, increased circulating tumor necrosis factor level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0008553, increased circulating tumor necrosis factor level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0008553, increased circulating tumor necrosis factor level</dd><dd>HP:0001873, Thrombocytopenia - MP:0000322, increased granulocyte number</dd><dd>HP:0002151, Increased serum lactate - MP:0008553, increased circulating tumor necrosis factor level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0001860, liver inflammation</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0001860, liver inflammation</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0001860, liver inflammation</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0005425, increased macrophage cell number</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001732, postnatal growth retardation</dd></dl><dl><dt>PhenIX semantic similarity score: 0.87 (p-value: 0.850660)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/607341">OMIM:607341</a> Focal cortical dysplasia, type II, somatic - somatic</dd>
+<dd><a href="http://www.omim.org/entry/616638">OMIM:616638</a> Smith-Kingsmore syndrome - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=457485">ORPHA:457485</a> Macrocephaly-intellectual disability-neurodevelopmental disorder-small thorax syndrome - autosomal dominant</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.486</b>
+                                    <data>(p=1.0E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.509</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.865</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.477 to OMIM:616638 Smith-Kingsmore syndrome</dt>
+                                
+                                    <dt>Phenotypic similarity 0.292 to ORPHA:457485 Macrocephaly-intellectual disability-neurodevelopmental disorder-small thorax syndrome</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>1-11199603-C-A [0/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting, PP3]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.865</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000361445.9">MTOR:ENST00000361445.9:c.4045G&gt;T:p.(Asp1349Tyr)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.86453384</dd>
+                                    
+                                    <dd>REVEL: 0.644</dd>
+                                    <dd>MVP: 0.865</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="TYW1B" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000277149">TYW1B</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.483</b>
+                    <data>(p=1.0E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.565</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.800</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.565 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=TYW1B">TYW1B</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia - MP:0000208, decreased hematocrit</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0000208, decreased hematocrit</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function - MP:0002966, decreased circulating alkaline phosphatase level</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0002966, decreased circulating alkaline phosphatase level</dd><dd>HP:0001399, Hepatic failure - MP:0002966, decreased circulating alkaline phosphatase level</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - MP:0005419, decreased circulating serum albumin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0005419, decreased circulating serum albumin level</dd><dd>HP:0001873, Thrombocytopenia - MP:0000208, decreased hematocrit</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0002966, decreased circulating alkaline phosphatase level</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0002966, decreased circulating alkaline phosphatase level</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0006243, impaired pupillary reflex</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0005641, increased mean corpuscular hemoglobin concentration</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.483</b>
+                                    <data>(p=1.0E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.565</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.800</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SPLICE_REGION_VARIANT</span>
+                            <b>SNV</b>
+                            <b>7-72629004-C-T [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs782670276">rs782670276</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.800</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000620995.5">TYW1B:ENST00000620995.5:c.1507-7G&gt;A:p.?</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>TOPMed: 0.0004%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="SLC25A31" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000151475">SLC25A31</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.482</b>
+                    <data>(p=1.0E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.501</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.872</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.124 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=SLC25A31">SLC25A31</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0014052, increased male germ cell apoptosis</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.501 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=SLC25A31%0DSLC25A4&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SLC25A4</a> and phenotypic similarity 0.609 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=254892">Autosomal dominant progressive external ophthalmoplegia</a> associated with SLC25A4.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001392, Abnormality of the liver</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - HP:0000969, Edema</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0000939, Osteoporosis</dd><dd>HP:0001396, Cholestasis - HP:0001392, Abnormality of the liver</dd><dd>HP:0001410, Decreased liver function - HP:0001392, Abnormality of the liver</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0001399, Hepatic failure - HP:0001392, Abnormality of the liver</dd><dd>HP:0000938, Osteopenia - HP:0000939, Osteoporosis</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001712, Left ventricular hypertrophy</dd><dd>HP:0200114, Metabolic alkalosis - HP:0002151, Increased serum lactate</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003236, Elevated circulating creatine kinase concentration</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003236, Elevated circulating creatine kinase concentration</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0002151, Increased serum lactate</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0009830, Peripheral neuropathy</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0000819, Diabetes mellitus</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001508, Failure to thrive</dd></dl><dl><dt>Proximity score 0.501 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=SLC25A31%0DSLC25A4&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SLC25A4</a> and phenotypic similarity 0.472 to mouse mutant of SLC25A4.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0001625, cardiac hypertrophy</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0001625, cardiac hypertrophy</dd><dd>HP:0200114, Metabolic alkalosis - MP:0030673, increased circulating alanine level</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0013405, increased circulating lactate level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.482</b>
+                                    <data>(p=1.0E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.501</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.872</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>4-127768852-C-T [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs372171427">rs372171427</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PP3_Moderate]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=2368923%5Balleleid%5D">(criteria provided, single submitter)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.872</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000281154.6">SLC25A31:ENST00000281154.6:c.734C&gt;T:p.(Thr245Ile)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.8798723</dd>
+                                    
+                                    <dd>REVEL: 0.785</dd>
+                                    <dd>MVP: 0.880</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>TOPMed: 0.0113%</dd>
+                                    <dd>ESP AA: 0.0454%</dd>
+                                    <dd>ESP All: 0.0154%</dd>
+                                    <dd>ExAC AFR: 0.0481%</dd>
+                                    <dd>ExAC AMR: 0.0087%</dd>
+                                    <dd>ExAC EAS: 0.0116%</dd>
+                                    <dd>gnomAD_E_AFR: 0.0470%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0032%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0181%</dd>
+                                    <dd>gnomAD_G_AFR: 0.0573%</dd>
+                                    <dd>gnomAD_G_EAS: 0.0619%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="DNAJB5" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000137094">DNAJB5</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.474</b>
+                    <data>(p=1.1E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.503</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.867</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.197 to zebrafish mutant involving <a href="http://zfin.org/action/quicksearch/query?query=DNAJB5">DNAJB5</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - ZP:0018468, axon peripheral neuron morphology, abnormal</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.503 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=DNAJB5%0DCLPB&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to CLPB</a> and phenotypic similarity 0.640 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=445038">3-methylglutaconic aciduria type 7</a> associated with CLPB.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001397, Hepatic steatosis</dd><dd>HP:0001903, Anemia - HP:0005528, Bone marrow hypocellularity</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001875, Neutropenia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0005528, Bone marrow hypocellularity</dd><dd>HP:0001396, Cholestasis - HP:0001397, Hepatic steatosis</dd><dd>HP:0001410, Decreased liver function - HP:0000821, Hypothyroidism</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0001399, Hepatic failure - HP:0000821, Hypothyroidism</dd><dd>HP:0000938, Osteopenia - HP:0005528, Bone marrow hypocellularity</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001638, Cardiomyopathy</dd><dd>HP:0200114, Metabolic alkalosis - HP:0002151, Increased serum lactate</dd><dd>HP:0003073, Hypoalbuminemia - HP:0002151, Increased serum lactate</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0001397, Hepatic steatosis</dd><dd>HP:0001873, Thrombocytopenia - HP:0001875, Neutropenia</dd><dd>HP:0002151, Increased serum lactate - HP:0002151, Increased serum lactate</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001397, Hepatic steatosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001875, Neutropenia</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.503 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=DNAJB5%0DCLPB&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to CLPB</a> and phenotypic similarity 0.212 to fish mutant of CLPB.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - ZP:0012655, axon cerebellum morphology, abnormal</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.474</b>
+                                    <data>(p=1.1E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.503</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.867</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>9-34996780-G-A [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs562575065">rs562575065</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.867</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000682809.1">DNAJB5:ENST00000682809.1:c.943G&gt;A:p.(Val315Ile)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.87513155</dd>
+                                    
+                                    <dd>REVEL: 0.399</dd>
+                                    <dd>MVP: 0.875</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0625%</dd>
+                                    <dd>TOPMed: 0.0068%</dd>
+                                    <dd>ExAC EAS: 0.0699%</dd>
+                                    <dd>ExAC SAS: 0.0305%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0581%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0018%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0228%</dd>
+                                    <dd>gnomAD_G_EAS: 0.0617%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="ATAD3A" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000197785">ATAD3A</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.462</b>
+                    <data>(p=1.1E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.864</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.553 to <a href="http://www.omim.org/entry/618810">Pontocerebellar hypoplasia, hypotonia, and respiratory insufficiency syndrome, neonatal lethal</a> associated with ATAD3A.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0002240, Hepatomegaly</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - HP:0002240, Hepatomegaly</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0002240, Hepatomegaly</dd><dd>HP:0001410, Decreased liver function - HP:0002240, Hepatomegaly</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0002240, Hepatomegaly</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001639, Hypertrophic cardiomyopathy</dd><dd>HP:0200114, Metabolic alkalosis - HP:0002151, Increased serum lactate</dd><dd>HP:0003073, Hypoalbuminemia - HP:0002151, Increased serum lactate</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003146, Hypocholesterolemia</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0002151, Increased serum lactate</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0003477, Peripheral axonal neuropathy</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0002240, Hepatomegaly</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.458 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=ATAD3A">ATAD3A</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - MP:0000186, decreased circulating HDL cholesterol level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0000186, decreased circulating HDL cholesterol level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ATAD3A%0DUSB1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to USB1</a> and phenotypic similarity 0.640 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=1775">Dyskeratosis congenita</a> associated with USB1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001744, Splenomegaly</dd><dd>HP:0001903, Anemia - HP:0001903, Anemia</dd><dd>HP:0001541, Ascites - HP:0002240, Hepatomegaly</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001903, Anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0005528, Bone marrow hypocellularity</dd><dd>HP:0001396, Cholestasis - HP:0001399, Hepatic failure</dd><dd>HP:0001410, Decreased liver function - HP:0001399, Hepatic failure</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0001399, Hepatic failure</dd><dd>HP:0000938, Osteopenia - HP:0000939, Osteoporosis</dd><dd>HP:0001642, Pulmonic stenosis - HP:0100585, Telangiectasia of the skin</dd><dd>HP:0200114, Metabolic alkalosis - HP:0000819, Diabetes mellitus</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - HP:0001873, Thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate - HP:0000819, Diabetes mellitus</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001394, Cirrhosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001874, Abnormality of neutrophils</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ATAD3A%0DUSB1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to USB1</a> and phenotypic similarity 0.279 to mouse mutant of USB1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - MP:0001785, edema</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ATAD3A%0DUSB1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to USB1</a> and phenotypic similarity 0.208 to fish mutant of USB1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - ZP:0001452, trunk edematous, abnormal</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.46 (p-value: 0.988820)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/617183">OMIM:617183</a> Harel-Yoon syndrome - autosomal dominant/recessive</dd>
+<dd><a href="http://www.omim.org/entry/618810">OMIM:618810</a> Pontocerebellar hypoplasia, hypotonia, and respiratory insufficiency syndrome, neonatal lethal - autosomal recessive</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=496790">ORPHA:496790</a> Ocular anomalies-axonal neuropathy-developmental delay syndrome - autosomal dominant/recessive</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.462</b>
+                                    <data>(p=1.1E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.864</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.485 to ORPHA:496790 Ocular anomalies-axonal neuropathy-developmental delay syndrome</dt>
+                                
+                                    <dt>Phenotypic similarity 0.465 to OMIM:617183 Harel-Yoon syndrome</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>1-1524324-G-A [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs1338018303">rs1338018303</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PP3_Moderate]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.864</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000378756.8">ATAD3A:ENST00000378756.8:c.1141G&gt;A:p.(Val381Met)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.8663908</dd>
+                                    
+                                    <dd>REVEL: 0.809</dd>
+                                    <dd>MVP: 0.866</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>gnomAD_E_NFE: 0.0018%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0183%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="ATXN1" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000124788">ATXN1</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.447</b>
+                    <data>(p=1.2E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.507</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.850</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.288 to <a href="http://www.omim.org/entry/164400">Spinocerebellar ataxia 1</a> associated with ATXN1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0007006, Dorsal column degeneration</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.392 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=ATXN1">ATXN1</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0004191, neuronal intranuclear inclusions</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0008489, slow postnatal weight gain</dd></dl><dl><dt>Proximity score 0.507 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ATXN1%0DATXN2&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to ATXN2</a> and phenotypic similarity 0.464 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=803">Amyotrophic lateral sclerosis</a> associated with ATXN2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - HP:0000217, Xerostomia</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function - HP:0000217, Xerostomia</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0000217, Xerostomia</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - HP:0000217, Xerostomia</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0000217, Xerostomia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0007373, Motor neuron atrophy</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.507 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ATXN1%0DATXN2&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to ATXN2</a> and phenotypic similarity 0.675 to mouse mutant of ATXN2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0002628, hepatic steatosis</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0002628, hepatic steatosis</dd><dd>HP:0001410, Decreased liver function - MP:0002628, hepatic steatosis</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0002628, hepatic steatosis</dd><dd>HP:0001399, Hepatic failure - MP:0002628, hepatic steatosis</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0002079, increased circulating insulin level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002079, increased circulating insulin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0005178, increased circulating cholesterol level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0002079, increased circulating insulin level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0002628, hepatic steatosis</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0002628, hepatic steatosis</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0010400, increased liver glycogen level</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0005455, increased susceptibility to weight gain</dd></dl><dl><dt>PhenIX semantic similarity score: 0.38 (p-value: 0.844500)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/164400">OMIM:164400</a> Spinocerebellar ataxia 1 - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=98755">ORPHA:98755</a> Spinocerebellar ataxia type 1 - autosomal dominant</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.447</b>
+                                    <data>(p=1.2E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.507</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.850</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.288 to OMIM:164400 Spinocerebellar ataxia 1</dt>
+                                
+                                    <dt>Phenotypic similarity 0.204 to ORPHA:98755 Spinocerebellar ataxia type 1</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">DISRUPTIVE_INFRAME_DELETION</span>
+                            <b>DEL</b>
+                            <b>6-16327684-ATGC-A [-/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs193922926">rs193922926</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=207394%5Balleleid%5D">(criteria provided, single submitter)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.850</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000436367.6">ATXN1:ENST00000436367.6:c.624_626del:p.(Gln208del)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.055</b>
+                                    <data>(p=3.4E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.253</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.850</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">DISRUPTIVE_INFRAME_INSERTION</span>
+                            <b>INS</b>
+                            <b>6-16327684-A-ATGCTGC [-/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs193922926">rs193922926</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                
+                                
+                                
+                                <span class="label label-danger">PATHOGENIC</span>
+                                
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=1770475%5Balleleid%5D">(no assertion criteria provided)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.850</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000436367.6">ATXN1:ENST00000436367.6:c.621_626dup:p.(Gln207_Gln208dup)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">DISRUPTIVE_INFRAME_DELETION</span>
+                            <b>DEL</b>
+                            <b>6-16327684-ATGC-A [-/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs193922926">rs193922926</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=207394%5Balleleid%5D">(criteria provided, single submitter)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.850</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000436367.6">ATXN1:ENST00000436367.6:c.624_626del:p.(Gln208del)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="MUC12" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000205277">MUC12</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.445</b>
+                    <data>(p=1.2E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.506</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.850</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Proximity score 0.506 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=MUC12%0DGALNT1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to GALNT1</a> and phenotypic similarity 0.745 to mouse mutant of GALNT1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0001903, Anemia - MP:0002607, decreased basophil cell number</dd><dd>HP:0001541, Ascites - MP:0005606, increased bleeding time</dd><dd>HP:0010972, Anemia of inadequate production - MP:0005012, decreased eosinophil cell number</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0002607, decreased basophil cell number</dd><dd>HP:0001396, Cholestasis - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0001410, Decreased liver function - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0001399, Hepatic failure - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0006128, pulmonary valve stenosis</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - MP:0005419, decreased circulating serum albumin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0005419, decreased circulating serum albumin level</dd><dd>HP:0001873, Thrombocytopenia - MP:0002607, decreased basophil cell number</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0010470, dilated ascending aorta</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.445</b>
+                                    <data>(p=1.2E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.506</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.850</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">INFRAME_INSERTION</span>
+                            <b>INS</b>
+                            <b>7-100969674-A-ACTG [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs150485202">rs150485202</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting, PM4]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.850</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000536621.6">MUC12:ENST00000536621.6:c.54_55insGCT:p.(Thr18_Thr19insAla)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.389</b>
+                                    <data>(p=1.4E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.506</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.825</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">INFRAME_INSERTION</span>
+                            <b>INS</b>
+                            <b>7-100969674-A-ACTG [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs150485202">rs150485202</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting, PM4]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.850</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000536621.6">MUC12:ENST00000536621.6:c.54_55insGCT:p.(Thr18_Thr19insAla)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SPLICE_REGION_VARIANT</span>
+                            <b>SNV</b>
+                            <b>7-100969688-A-G [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs73168328">rs73168328</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.800</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000536621.6">MUC12:ENST00000536621.6:c.66A&gt;G:p.(=)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+                <div class="row">
+                    <div class="col-sm-12">
+                        <b>Other passed variants:</b>
+                    </div>
+                </div>
+                
+                
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">MISSENSE_VARIANT</span>
+                        <b>SNV</b>
+                        <b>7-100969671-G-A [0/1]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs79881008">rs79881008</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.012</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000536621.6">MUC12:ENST00000536621.6:c.49G&gt;A:p.(Val17Ile)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            <dd>Best Score: 0.012</dd>
+                            
+                            <dd>REVEL: 0.012</dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            <dd>No frequency data</dd>
+                            
+                        </dl>
+                    </div>
+                </div>
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="CEL" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000170835">CEL</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.437</b>
+                    <data>(p=1.2E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.517</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.834</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.476 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=552">MODY</a> associated with CEL.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0012028, Hepatocellular adenoma</dd><dd>HP:0001903, Anemia - HP:0040217, Elevated hemoglobin A1c</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - HP:0040217, Elevated hemoglobin A1c</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0040217, Elevated hemoglobin A1c</dd><dd>HP:0001396, Cholestasis - HP:0012028, Hepatocellular adenoma</dd><dd>HP:0001410, Decreased liver function - HP:0001738, Exocrine pancreatic insufficiency</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0001738, Exocrine pancreatic insufficiency</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - HP:0000825, Hyperinsulinemic hypoglycemia</dd><dd>HP:0003073, Hypoalbuminemia - HP:0030794, Abnormal circulating C-peptide concentration</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0030794, Abnormal circulating C-peptide concentration</dd><dd>HP:0001873, Thrombocytopenia - HP:0040217, Elevated hemoglobin A1c</dd><dd>HP:0002151, Increased serum lactate - HP:0000825, Hyperinsulinemic hypoglycemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0000831, Insulin-resistant diabetes mellitus</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0040217, Elevated hemoglobin A1c</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001520, Large for gestational age</dd></dl><dl><dt>Phenotypic similarity 0.236 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=CEL">CEL</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0005342, abnormal intestinal lipid absorption</dd><dd>HP:0001410, Decreased liver function - MP:0005342, abnormal intestinal lipid absorption</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0005342, abnormal intestinal lipid absorption</dd><dd>HP:0001399, Hepatic failure - MP:0005342, abnormal intestinal lipid absorption</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0005342, abnormal intestinal lipid absorption</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0005342, abnormal intestinal lipid absorption</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0005342, abnormal intestinal lipid absorption</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.517 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=CEL%0DLIPA&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to LIPA</a> and phenotypic similarity 0.854 to <a href="http://www.omim.org/entry/278000">Cholesteryl ester storage disease</a> associated with LIPA.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0001903, Anemia - HP:0001903, Anemia</dd><dd>HP:0001541, Ascites - HP:0001538, Protuberant abdomen</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001903, Anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001882, Leukopenia</dd><dd>HP:0001396, Cholestasis - HP:0001399, Hepatic failure</dd><dd>HP:0001410, Decreased liver function - HP:0001399, Hepatic failure</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0031964, Elevated circulating alanine aminotransferase concentration</dd><dd>HP:0001399, Hepatic failure - HP:0001399, Hepatic failure</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001409, Portal hypertension</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003282, Low alkaline phosphatase</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003233, Decreased HDL cholesterol concentration</dd><dd>HP:0001873, Thrombocytopenia - HP:0001873, Thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate - HP:0002155, Hypertriglyceridemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0031964, Elevated circulating alanine aminotransferase concentration</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0031956, Elevated circulating aspartate aminotransferase concentration</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001397, Hepatic steatosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0004333, Bone-marrow foam cells</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001508, Failure to thrive</dd></dl><dl><dt>Proximity score 0.517 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=CEL%0DLIPA&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to LIPA</a> and phenotypic similarity 0.706 to mouse mutant of LIPA.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0031058, hepatosplenomegaly</dd><dd>HP:0001903, Anemia - MP:0008245, abnormal alveolar macrophage morphology</dd><dd>HP:0001541, Ascites - MP:0002981, increased liver weight</dd><dd>HP:0010972, Anemia of inadequate production - MP:0008245, abnormal alveolar macrophage morphology</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0008245, abnormal alveolar macrophage morphology</dd><dd>HP:0001396, Cholestasis - MP:0000598, abnormal liver morphology</dd><dd>HP:0001410, Decreased liver function - MP:0000598, abnormal liver morphology</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000598, abnormal liver morphology</dd><dd>HP:0001399, Hepatic failure - MP:0000598, abnormal liver morphology</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0002079, increased circulating insulin level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002079, increased circulating insulin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0000186, decreased circulating HDL cholesterol level</dd><dd>HP:0001873, Thrombocytopenia - MP:0008245, abnormal alveolar macrophage morphology</dd><dd>HP:0002151, Increased serum lactate - MP:0001554, increased circulating free fatty acids level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000598, abnormal liver morphology</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000598, abnormal liver morphology</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0000820, abnormal choroid plexus morphology</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0002628, hepatic steatosis</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0008245, abnormal alveolar macrophage morphology</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001262, decreased body weight</dd></dl><dl><dt>PhenIX semantic similarity score: 0.63 (p-value: 0.000390)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/609812">OMIM:609812</a> Maturity-onset diabetes of the young, type VIII - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=552">ORPHA:552</a> MODY - autosomal dominant</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.437</b>
+                                    <data>(p=1.2E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.517</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.834</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.476 to ORPHA:552 MODY</dt>
+                                
+                                    <dt>Phenotypic similarity 0.434 to OMIM:609812 Maturity-onset diabetes of the young, type VIII</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>9-133068761-G-A [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs746397927">rs746397927</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.834</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000372080.8">CEL:ENST00000372080.8:c.985G&gt;A:p.(Asp329Asn)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.841606</dd>
+                                    
+                                    <dd>REVEL: 0.269</dd>
+                                    <dd>MVP: 0.842</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>gnomAD_E_AFR: 0.0167%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0324%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0020%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0200%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0071%</dd>
+                                    <dd>gnomAD_G_AFR: 0.0247%</dd>
+                                    <dd>gnomAD_G_EAS: 0.0632%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="MADCAM1" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000099866">MADCAM1</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.433</b>
+                    <data>(p=1.2E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.501</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.850</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.277 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=MADCAM1">MADCAM1</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0008135, small Peyer's patches</dd><dd>HP:0001903, Anemia - MP:0005017, decreased B cell number</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0005017, decreased B cell number</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0005017, decreased B cell number</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - MP:0005017, decreased B cell number</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0005017, decreased B cell number</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.501 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=MADCAM1%0DIL10&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to IL10</a> and phenotypic similarity 0.493 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=536">Systemic lupus erythematosus</a> associated with IL10.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0002716, Lymphadenopathy</dd><dd>HP:0001903, Anemia - HP:0001878, Hemolytic anemia</dd><dd>HP:0001541, Ascites - HP:0100755, Abnormality of salivation</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001878, Hemolytic anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001882, Leukopenia</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia - HP:0001369, Arthritis</dd><dd>HP:0001642, Pulmonic stenosis - HP:0000822, Hypertension</dd><dd>HP:0200114, Metabolic alkalosis - HP:0100755, Abnormality of salivation</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - HP:0001873, Thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate - HP:0100755, Abnormality of salivation</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001882, Leukopenia</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.501 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=MADCAM1%0DIL10&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to IL10</a> and phenotypic similarity 0.742 to mouse mutant of IL10.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0008477, decreased spleen red pulp amount</dd><dd>HP:0001903, Anemia - MP:0001577, anemia</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0002810, microcytic anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0008246, abnormal leukocyte morphology</dd><dd>HP:0001396, Cholestasis - MP:0000609, abnormal liver physiology</dd><dd>HP:0001410, Decreased liver function - MP:0000609, abnormal liver physiology</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000609, abnormal liver physiology</dd><dd>HP:0001399, Hepatic failure - MP:0000609, abnormal liver physiology</dd><dd>HP:0000938, Osteopenia - MP:0002896, abnormal bone mineralization</dd><dd>HP:0001642, Pulmonic stenosis - MP:0003037, increased myocardial infarct size</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005554, decreased circulating creatinine level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0000199, abnormal circulating serum albumin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0005179, decreased circulating cholesterol level</dd><dd>HP:0001873, Thrombocytopenia - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0002151, Increased serum lactate - MP:0005554, decreased circulating creatinine level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000609, abnormal liver physiology</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000609, abnormal liver physiology</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0009355, increased liver triglyceride level</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0000322, increased granulocyte number</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001732, postnatal growth retardation</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.433</b>
+                                    <data>(p=1.2E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.501</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.850</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">DISRUPTIVE_INFRAME_INSERTION</span>
+                            <b>INS</b>
+                            <b>19-501743-T-TCTCCCGACACCACCTCCCCGGAGTCTCCCGACACCACCTCCCAGGAGC [-/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.850</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000215637.8">MADCAM1:ENST00000215637.8:c.760_761insCGGAGTCTCCCGACACCACCTCCCAGGAGCCTCCCGACACCACCTCCC:p.(Ser253_Gln254insProGluSerProAspThrThrSerGlnGluProProAspThrThrSer)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="KCNN3" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000143603">KCNN3</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.430</b>
+                    <data>(p=1.2E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.850</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.394 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=3473">Zimmermann-Laband syndrome</a> associated with KCNN3.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001744, Splenomegaly</dd><dd>HP:0001903, Anemia - HP:0001744, Splenomegaly</dd><dd>HP:0001541, Ascites - HP:0002240, Hepatomegaly</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001744, Splenomegaly</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001744, Splenomegaly</dd><dd>HP:0001396, Cholestasis - HP:0002240, Hepatomegaly</dd><dd>HP:0001410, Decreased liver function - HP:0002240, Hepatomegaly</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0002240, Hepatomegaly</dd><dd>HP:0000938, Osteopenia - HP:0001382, Joint hypermobility</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - HP:0001744, Splenomegaly</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0002240, Hepatomegaly</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001744, Splenomegaly</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=KCNN3%0DBPNT1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to BPNT1</a> and phenotypic similarity 0.638 to mouse mutant of BPNT1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000599, enlarged liver</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - MP:0011738, anasarca</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0000603, pale liver</dd><dd>HP:0001410, Decreased liver function - MP:0000603, pale liver</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000603, pale liver</dd><dd>HP:0001399, Hepatic failure - MP:0000603, pale liver</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005343, increased circulating aspartate transaminase level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0005419, decreased circulating serum albumin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0003983, decreased cholesterol level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0005343, increased circulating aspartate transaminase level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000603, pale liver</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000603, pale liver</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000607, abnormal hepatocyte morphology</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/618658">OMIM:618658</a> Zimmermann-Laband syndrome 3 - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=3473">ORPHA:3473</a> Zimmermann-Laband syndrome - autosomal dominant</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.430</b>
+                                    <data>(p=1.2E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.850</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.394 to ORPHA:3473 Zimmermann-Laband syndrome</dt>
+                                
+                                    <dt>Phenotypic similarity 0.179 to OMIM:618658 Zimmermann-Laband syndrome 3</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">DISRUPTIVE_INFRAME_DELETION</span>
+                            <b>DEL</b>
+                            <b>1-154869723-GGCTGCTGCT-G [-/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs3831942">rs3831942</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting, BP6]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    <span class="label label-success">BENIGN</span>
+                                
+                                
+                                
+                                
+                                
+                                
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=1677442%5Balleleid%5D">(criteria provided, single submitter)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.850</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000271915.9">KCNN3:ENST00000271915.9:c.233_241del:p.(Gln78_Gln80del)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="SCRT2" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000215397">SCRT2</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.430</b>
+                    <data>(p=1.2E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.850</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.254 to zebrafish mutant involving <a href="http://zfin.org/action/quicksearch/query?query=SCRT2">SCRT2</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - ZP:0003800, spinal cord has extra parts of type neuron, abnormal</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=SCRT2%0DIRF2BP2&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to IRF2BP2</a> and phenotypic similarity 0.667 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=1572">Common variable immunodeficiency</a> associated with IRF2BP2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001744, Splenomegaly</dd><dd>HP:0001903, Anemia - HP:0001878, Hemolytic anemia</dd><dd>HP:0001541, Ascites - HP:0001744, Splenomegaly</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001878, Hemolytic anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001888, Lymphopenia</dd><dd>HP:0001396, Cholestasis - HP:0001392, Abnormality of the liver</dd><dd>HP:0001410, Decreased liver function - HP:0001392, Abnormality of the liver</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0001399, Hepatic failure - HP:0001392, Abnormality of the liver</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0000979, Purpura</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - HP:0001973, Autoimmune thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001392, Abnormality of the liver</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001888, Lymphopenia</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001531, Failure to thrive in infancy</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=SCRT2%0DIRF2BP2&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to IRF2BP2</a> and phenotypic similarity 0.543 to mouse mutant of IRF2BP2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000598, abnormal liver morphology</dd><dd>HP:0001903, Anemia - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0004229, abnormal embryonic erythropoiesis</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0002416, abnormal proerythroblast morphology</dd><dd>HP:0001396, Cholestasis - MP:0000598, abnormal liver morphology</dd><dd>HP:0001410, Decreased liver function - MP:0000598, abnormal liver morphology</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000598, abnormal liver morphology</dd><dd>HP:0001399, Hepatic failure - MP:0000598, abnormal liver morphology</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000598, abnormal liver morphology</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000598, abnormal liver morphology</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000598, abnormal liver morphology</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0002416, abnormal proerythroblast morphology</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001732, postnatal growth retardation</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.430</b>
+                                    <data>(p=1.2E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.850</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">INFRAME_INSERTION</span>
+                            <b>INS</b>
+                            <b>20-663718-T-TGGCGCAGGCCGCCTC [0/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting, PM4]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.850</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000246104.7">SCRT2:ENST00000246104.7:c.862_876dup:p.(Glu288_Ala292dup)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="UTF1" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000171794">UTF1</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.430</b>
+                    <data>(p=1.2E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.850</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.326 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=UTF1">UTF1</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0000060, delayed bone ossification</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia - MP:0000060, delayed bone ossification</dd><dd>HP:0001642, Pulmonic stenosis - MP:0002652, thin myocardium</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0004201, fetal growth retardation</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=UTF1%0DZSCAN10&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to ZSCAN10</a> and phenotypic similarity 0.676 to mouse mutant of ZSCAN10.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0002981, increased liver weight</dd><dd>HP:0001903, Anemia - MP:0002599, increased mean platelet volume</dd><dd>HP:0001541, Ascites - MP:0002981, increased liver weight</dd><dd>HP:0010972, Anemia of inadequate production - MP:0005014, increased B cell number</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0004016, decreased bone mass</dd><dd>HP:0001396, Cholestasis - MP:0002981, increased liver weight</dd><dd>HP:0001410, Decreased liver function - MP:0002981, increased liver weight</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0002981, increased liver weight</dd><dd>HP:0001399, Hepatic failure - MP:0002981, increased liver weight</dd><dd>HP:0000938, Osteopenia - MP:0004016, decreased bone mass</dd><dd>HP:0001642, Pulmonic stenosis - MP:0003921, abnormal heart left ventricle morphology</dd><dd>HP:0200114, Metabolic alkalosis - MP:0003020, decreased circulating chloride level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0005419, decreased circulating serum albumin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0002665, decreased circulating corticosterone level</dd><dd>HP:0001873, Thrombocytopenia - MP:0003179, thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate - MP:0005553, increased circulating creatinine level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0002981, increased liver weight</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0002981, increased liver weight</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0002981, increased liver weight</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0003944, abnormal T cell subpopulation ratio</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001262, decreased body weight</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.430</b>
+                                    <data>(p=1.2E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.850</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">DISRUPTIVE_INFRAME_DELETION</span>
+                            <b>DEL</b>
+                            <b>10-133230985-CCGCCCG-C [0/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.850</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000304477.3">UTF1:ENST00000304477.3:c.572_577del:p.(Ala191_Arg192del)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="LNP1" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000206535">LNP1</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.430</b>
+                    <data>(p=1.2E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.850</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=LNP1%0DSCO1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SCO1</a> and phenotypic similarity 0.675 to <a href="http://www.omim.org/entry/619048">Mitochondrial complex IV deficiency, nuclear type 4</a> associated with SCO1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0002240, Hepatomegaly</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - HP:0002240, Hepatomegaly</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0002240, Hepatomegaly</dd><dd>HP:0001410, Decreased liver function - HP:0002240, Hepatomegaly</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0031956, Elevated circulating aspartate aminotransferase concentration</dd><dd>HP:0001399, Hepatic failure - HP:0002240, Hepatomegaly</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001714, Ventricular hypertrophy</dd><dd>HP:0200114, Metabolic alkalosis - HP:0001942, Metabolic acidosis</dd><dd>HP:0003073, Hypoalbuminemia - HP:0002151, Increased serum lactate</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0008315, Decreased plasma free carnitine</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0002151, Increased serum lactate</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0031964, Elevated circulating alanine aminotransferase concentration</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0031956, Elevated circulating aspartate aminotransferase concentration</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001397, Hepatic steatosis</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001508, Failure to thrive</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.430</b>
+                                    <data>(p=1.2E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.850</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">DISRUPTIVE_INFRAME_INSERTION</span>
+                            <b>INS</b>
+                            <b>3-100451756-A-ATCCTAGAAGGCATTCTCATGAGGACCAGGAATTCCGATGCCGATCGTCTGACCGTCT [1/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs71132521">rs71132521</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.850</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000383693.8">LNP1:ENST00000383693.8:c.221_222insGGAATTCCGATGCCGATCGTCTGACCGTCTTCCTAGAAGGCATTCTCATGAGGACCA:p.(Ser80_His81insSerAspArgLeuProArgArgHisSerHisGluAspGlnGluPheArgCysArgSer)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="CORO6" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000167549">CORO6</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.429</b>
+                    <data>(p=1.2E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.502</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.848</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Proximity score 0.502 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=CORO6%0DMYO5B&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to MYO5B</a> and phenotypic similarity 0.716 to <a href="http://www.omim.org/entry/619868">Cholestasis, progressive familial intrahepatic, 10</a> associated with MYO5B.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001744, Splenomegaly</dd><dd>HP:0001903, Anemia - HP:0001744, Splenomegaly</dd><dd>HP:0001541, Ascites - HP:0002240, Hepatomegaly</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001744, Splenomegaly</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001744, Splenomegaly</dd><dd>HP:0001396, Cholestasis - HP:0011985, Acholic stools</dd><dd>HP:0001410, Decreased liver function - HP:0011985, Acholic stools</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0031956, Elevated circulating aspartate aminotransferase concentration</dd><dd>HP:0001399, Hepatic failure - HP:0011985, Acholic stools</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - HP:0003573, Increased total bilirubin</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003073, Hypoalbuminemia</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003124, Hypercholesterolemia</dd><dd>HP:0001873, Thrombocytopenia - HP:0001744, Splenomegaly</dd><dd>HP:0002151, Increased serum lactate - HP:0003573, Increased total bilirubin</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0031964, Elevated circulating alanine aminotransferase concentration</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0031956, Elevated circulating aspartate aminotransferase concentration</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0002240, Hepatomegaly</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001744, Splenomegaly</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001508, Failure to thrive</dd></dl><dl><dt>Proximity score 0.502 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=CORO6%0DMYO5B&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to MYO5B</a> and phenotypic similarity 0.330 to mouse mutant of MYO5B.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0005036, diarrhea</dd><dd>HP:0001410, Decreased liver function - MP:0005036, diarrhea</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0005036, diarrhea</dd><dd>HP:0001399, Hepatic failure - MP:0005036, diarrhea</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0005036, diarrhea</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0005036, diarrhea</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000189, hypoglycemia</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001262, decreased body weight</dd></dl><dl><dt>Proximity score 0.502 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=CORO6%0DMYO5B&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to MYO5B</a> and phenotypic similarity 0.245 to fish mutant of MYO5B.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - ZP:0006598, cardiac ventricle hypotrophic, abnormal</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - ZP:0011709, cranial nerve II has fewer parts of type axon retinal ganglion cell, abnormal</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - ZP:0107218, cardiac ventricle decreased occurrence cardiac chamber ballooning, abnormal</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.429</b>
+                                    <data>(p=1.2E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.502</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.848</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>17-29616744-A-G [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs377223092">rs377223092</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.848</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000388767.8">CORO6:ENST00000388767.8:c.962T&gt;C:p.(Met321Thr)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.8591861</dd>
+                                    
+                                    <dd>REVEL: 0.639</dd>
+                                    <dd>MVP: 0.859</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0937%</dd>
+                                    <dd>TOPMed: 0.0937%</dd>
+                                    <dd>ExAC EAS: 0.0925%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0812%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0182%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0097%</dd>
+                                    <dd>gnomAD_G_NFE: 0.0067%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="DSPP" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000152591">DSPP</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.428</b>
+                    <data>(p=1.2E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.501</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.848</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.247 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=DSPP">DSPP</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0030484, abnormal osteocyte lacuna morphology</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia - MP:0030484, abnormal osteocyte lacuna morphology</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.501 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=DSPP%0DHSPG2&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to HSPG2</a> and phenotypic similarity 0.507 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=1606">1p36 deletion syndrome</a> associated with HSPG2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001743, Abnormality of the spleen</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0000902, Rib fusion</dd><dd>HP:0001396, Cholestasis - HP:0001392, Abnormality of the liver</dd><dd>HP:0001410, Decreased liver function - HP:0001392, Abnormality of the liver</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0001392, Abnormality of the liver</dd><dd>HP:0000938, Osteopenia - HP:0000902, Rib fusion</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001636, Tetralogy of Fallot</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0001397, Hepatic steatosis</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0003416, Spinal canal stenosis</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001397, Hepatic steatosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0005113, Aortic arch aneurysm</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001508, Failure to thrive</dd></dl><dl><dt>Proximity score 0.501 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=DSPP%0DHSPG2&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to HSPG2</a> and phenotypic similarity 0.609 to mouse mutant of HSPG2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000602, dilated liver sinusoidal space</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - MP:0005244, hemopericardium</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0000065, abnormal bone marrow cavity morphology</dd><dd>HP:0001396, Cholestasis - MP:0000602, dilated liver sinusoidal space</dd><dd>HP:0001410, Decreased liver function - MP:0000602, dilated liver sinusoidal space</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000602, dilated liver sinusoidal space</dd><dd>HP:0001399, Hepatic failure - MP:0000602, dilated liver sinusoidal space</dd><dd>HP:0000938, Osteopenia - MP:0008272, abnormal endochondral bone ossification</dd><dd>HP:0001642, Pulmonic stenosis - MP:0002748, abnormal pulmonary valve morphology</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000602, dilated liver sinusoidal space</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000602, dilated liver sinusoidal space</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0002152, abnormal brain morphology</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000602, dilated liver sinusoidal space</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0010472, abnormal ascending aorta and coronary artery attachment</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0000547, short limbs</dd></dl><dl><dt>Proximity score 0.501 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=DSPP%0DHSPG2&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to HSPG2</a> and phenotypic similarity 0.222 to fish mutant of HSPG2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - ZP:0000038, pericardium edematous, abnormal</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - ZP:0006851, cardiac ventricle elongated, abnormal</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - ZP:0000530, dorsal aorta collapsed, abnormal</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.03 (p-value: 0.999050)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/125420">OMIM:125420</a> Dentin dysplasia, type II - autosomal dominant</dd>
+<dd><a href="http://www.omim.org/entry/125490">OMIM:125490</a> Dentinogenesis imperfecta, Shields type II - autosomal dominant</dd>
+<dd><a href="http://www.omim.org/entry/125500">OMIM:125500</a> Dentinogenesis imperfecta, Shields type III - autosomal dominant</dd>
+<dd><a href="http://www.omim.org/entry/605594">OMIM:605594</a> Deafness, autosomal dominant 39, with dentinogenesis - autosomal dominant</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.428</b>
+                                    <data>(p=1.2E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.501</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.848</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">DISRUPTIVE_INFRAME_DELETION</span>
+                            <b>DEL</b>
+                            <b>4-87615776-CAGCAGCGAT-C [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs763791363">rs763791363</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.848</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000651931.1">DSPP:ENST00000651931.1:c.3120_3128del:p.(Asp1053_Ser1055del)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>gnomAD_E_AMR: 0.0048%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0114%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0062%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0048%</dd>
+                                    <dd>gnomAD_G_NFE: 0.0173%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="EDC4" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000038358">EDC4</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.427</b>
+                    <data>(p=1.2E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.849</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.355 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=EDC4">EDC4</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=EDC4%0DSKIC3&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SKIC3</a> and phenotypic similarity 0.689 to <a href="http://www.omim.org/entry/222470">Trichohepatoenteric syndrome 1</a> associated with SKIC3.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001744, Splenomegaly</dd><dd>HP:0001903, Anemia - HP:0011877, Increased mean platelet volume</dd><dd>HP:0001541, Ascites - HP:0002240, Hepatomegaly</dd><dd>HP:0010972, Anemia of inadequate production - HP:0011877, Increased mean platelet volume</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0011877, Increased mean platelet volume</dd><dd>HP:0001396, Cholestasis - HP:0001396, Cholestasis</dd><dd>HP:0001410, Decreased liver function - HP:0001399, Hepatic failure</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0001399, Hepatic failure</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001642, Pulmonic stenosis</dd><dd>HP:0200114, Metabolic alkalosis - HP:0003235, Hypermethioninemia</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003073, Hypoalbuminemia</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003073, Hypoalbuminemia</dd><dd>HP:0001873, Thrombocytopenia - HP:0001894, Thrombocytosis</dd><dd>HP:0002151, Increased serum lactate - HP:0003235, Hypermethioninemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001395, Hepatic fibrosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0011877, Increased mean platelet volume</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001508, Failure to thrive</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=EDC4%0DTTC37&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to TTC37</a> and phenotypic similarity 0.361 to mouse mutant of TTC37.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0011874, enlarged urinary bladder</dd><dd>HP:0001903, Anemia - MP:0005641, increased mean corpuscular hemoglobin concentration</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0005641, increased mean corpuscular hemoglobin concentration</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005627, increased circulating potassium level</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - MP:0005641, increased mean corpuscular hemoglobin concentration</dd><dd>HP:0002151, Increased serum lactate - MP:0005627, increased circulating potassium level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0005641, increased mean corpuscular hemoglobin concentration</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.427</b>
+                                    <data>(p=1.2E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.849</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">DISRUPTIVE_INFRAME_DELETION</span>
+                            <b>DEL</b>
+                            <b>16-67879894-CAGCAGCAGT-C [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs769592693">rs769592693</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.849</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000358933.10">EDC4:ENST00000358933.10:c.1875_1883del:p.(Ser627_Ser629del)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>ExAC NFE: 0.0031%</dd>
+                                    <dd>ExAC SAS: 0.0122%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0030%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0036%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0097%</dd>
+                                    <dd>gnomAD_G_AFR: 0.0115%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="LMOD2" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000170807">LMOD2</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.426</b>
+                    <data>(p=1.2E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.848</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.379 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=154">Familial isolated dilated cardiomyopathy</a> associated with LMOD2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001874, Abnormality of neutrophils</dd><dd>HP:0001903, Anemia - HP:0001874, Abnormality of neutrophils</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001874, Abnormality of neutrophils</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001874, Abnormality of neutrophils</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001644, Dilated cardiomyopathy</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003236, Elevated circulating creatine kinase concentration</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003236, Elevated circulating creatine kinase concentration</dd><dd>HP:0001873, Thrombocytopenia - HP:0001874, Abnormality of neutrophils</dd><dd>HP:0002151, Increased serum lactate - HP:0003236, Elevated circulating creatine kinase concentration</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001874, Abnormality of neutrophils</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.327 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=LMOD2">LMOD2</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0002833, increased heart weight</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0000280, thin ventricular wall</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001262, decreased body weight</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=LMOD2%0DTCF4&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to TCF4</a> and phenotypic similarity 0.727 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=171">Primary sclerosing cholangitis</a> associated with TCF4.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0001903, Anemia - HP:0001879, Abnormal eosinophil morphology</dd><dd>HP:0001541, Ascites - HP:0001541, Ascites</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001879, Abnormal eosinophil morphology</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001879, Abnormal eosinophil morphology</dd><dd>HP:0001396, Cholestasis - HP:0001396, Cholestasis</dd><dd>HP:0001410, Decreased liver function - HP:0100626, Chronic hepatic failure</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0001399, Hepatic failure - HP:0100626, Chronic hepatic failure</dd><dd>HP:0000938, Osteopenia - HP:0000938, Osteopenia</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001635, Congestive heart failure</dd><dd>HP:0200114, Metabolic alkalosis - HP:0001945, Fever</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003073, Hypoalbuminemia</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0100512, Low levels of vitamin D</dd><dd>HP:0001873, Thrombocytopenia - HP:0001879, Abnormal eosinophil morphology</dd><dd>HP:0002151, Increased serum lactate - HP:0003073, Hypoalbuminemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001394, Cirrhosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0100727, Histiocytosis</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001824, Weight loss</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=LMOD2%0DTCF4&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to TCF4</a> and phenotypic similarity 0.315 to mouse mutant of TCF4.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0005090, increased double-negative T cell number</dd><dd>HP:0001903, Anemia - MP:0002145, abnormal T cell differentiation</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0002145, abnormal T cell differentiation</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0002145, abnormal T cell differentiation</dd><dd>HP:0001396, Cholestasis - MP:0005090, increased double-negative T cell number</dd><dd>HP:0001410, Decreased liver function - MP:0005090, increased double-negative T cell number</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0005090, increased double-negative T cell number</dd><dd>HP:0001399, Hepatic failure - MP:0005090, increased double-negative T cell number</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - MP:0002145, abnormal T cell differentiation</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0005090, increased double-negative T cell number</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0005090, increased double-negative T cell number</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0005090, increased double-negative T cell number</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0002145, abnormal T cell differentiation</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/619897">OMIM:619897</a> Cardiomyopathy, dilated, 2G - autosomal recessive</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=154">ORPHA:154</a> Familial isolated dilated cardiomyopathy - autosomal recessive</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.426</b>
+                                    <data>(p=1.2E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.848</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.379 to ORPHA:154 Familial isolated dilated cardiomyopathy</dt>
+                                
+                                    <dt>Phenotypic similarity 0.259 to OMIM:619897 Cardiomyopathy, dilated, 2G</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">DISRUPTIVE_INFRAME_DELETION</span>
+                            <b>DEL</b>
+                            <b>7-123662846-ACCT-A [1/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs577158076">rs577158076</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.848</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000458573.3">LMOD2:ENST00000458573.3:c.1272_1274del:p.(Pro433del)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>gnomAD_E_AFR: 0.0147%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0032%</dd>
+                                    <dd>gnomAD_E_FIN: 0.0048%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0020%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="FN1" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000115414">FN1</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.409</b>
+                    <data>(p=1.3E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.538</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.797</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.538 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=93315">Spondylometaphyseal dysplasia, 'corner fracture' type</a> associated with FN1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001891, Iron deficiency anemia</dd><dd>HP:0001903, Anemia - HP:0001891, Iron deficiency anemia</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001891, Iron deficiency anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001891, Iron deficiency anemia</dd><dd>HP:0001396, Cholestasis - HP:0031427, Abnormal circulating osteocalcin level</dd><dd>HP:0001410, Decreased liver function - HP:0031427, Abnormal circulating osteocalcin level</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0031427, Abnormal circulating osteocalcin level</dd><dd>HP:0000938, Osteopenia - HP:0004349, Reduced bone mineral density</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - HP:0031427, Abnormal circulating osteocalcin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0031427, Abnormal circulating osteocalcin level</dd><dd>HP:0001873, Thrombocytopenia - HP:0001891, Iron deficiency anemia</dd><dd>HP:0002151, Increased serum lactate - HP:0031427, Abnormal circulating osteocalcin level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0031427, Abnormal circulating osteocalcin level</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001891, Iron deficiency anemia</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.437 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=FN1">FN1</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia - MP:0001577, anemia</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0001577, anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0000292, distended pericardium</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - MP:0001577, anemia</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0003400, kinked neural tube</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0001577, anemia</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.222 to zebrafish mutant involving <a href="http://zfin.org/action/quicksearch/query?query=FN1">FN1</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - ZP:0001722, atrioventricular valve morphology, abnormal</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.519 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=FN1%0DFGL1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to FGL1</a> and phenotypic similarity 0.605 to mouse mutant of FGL1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0004847, abnormal liver weight</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0004847, abnormal liver weight</dd><dd>HP:0001410, Decreased liver function - MP:0004847, abnormal liver weight</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0004847, abnormal liver weight</dd><dd>HP:0001399, Hepatic failure - MP:0004847, abnormal liver weight</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0002702, decreased circulating free fatty acids level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0000186, decreased circulating HDL cholesterol level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0000186, decreased circulating HDL cholesterol level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0002702, decreased circulating free fatty acids level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0004847, abnormal liver weight</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0004847, abnormal liver weight</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0031115, macrovesicular hepatic steatosis</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001260, increased body weight</dd></dl><dl><dt>PhenIX semantic similarity score: 0.90 (p-value: 0.714220)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/184255">OMIM:184255</a> Spondylometaphyseal dysplasia, corner fracture type - autosomal dominant</dd>
+<dd><a href="http://www.omim.org/entry/601894">OMIM:601894</a> Glomerulopathy with fibronectin deposits 2 - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=84090">ORPHA:84090</a> Fibronectin glomerulopathy - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=93315">ORPHA:93315</a> Spondylometaphyseal dysplasia, 'corner fracture' type - autosomal dominant</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.409</b>
+                                    <data>(p=1.3E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.538</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.797</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.538 to ORPHA:93315 Spondylometaphyseal dysplasia, &#39;corner fracture&#39; type</dt>
+                                
+                                    <dt>Phenotypic similarity 0.507 to ORPHA:84090 Fibronectin glomerulopathy</dt>
+                                
+                                    <dt>Phenotypic similarity 0.132 to OMIM:601894 Glomerulopathy with fibronectin deposits 2</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SPLICE_REGION_VARIANT</span>
+                            <b>SNV</b>
+                            <b>2-215433325-T-C [0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs368265641">rs368265641</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=1371493%5Balleleid%5D">(criteria provided, single submitter)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.797</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000354785.11">FN1:ENST00000354785.11:c.414A&gt;G:p.(=)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0156%</dd>
+                                    <dd>TOPMed: 0.0008%</dd>
+                                    <dd>ExAC EAS: 0.0231%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0232%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0032%</dd>
+                                    <dd>gnomAD_G_NFE: 0.0067%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+
+    
+
+    <div id="about">
+        <h3>About</h3>
+        <p>
+            The Exomizer is a Java program that functionally annotates variants from whole-exome
+            sequencing data starting from a VCF file (version 4). The functional annotation code is
+            based on <a href="https://github.com/charite/jannovar/">Jannovar</a> and uses
+            <a href="https://genome.ucsc.edu/">UCSC</a> KnownGene transcript definitions and
+            hg19 genomic coordinates
+        </p>
+        <p>
+            Variants are prioritized according to user-defined criteria on variant frequency, pathogenicity,
+            quality, inheritance pattern, and model organism phenotype data. Predicted pathogenicity data
+            was extracted from the <a href="https://www.ncbi.nlm.nih.gov/pubmed/21520341">dbNSFP</a> resource.
+        </p>
+        <p>
+            Developed by the Computational Biology and Bioinformatics group at the
+            <a href="https://genetik.charite.de/">Institute for Medical Genetics and Human Genetics</a> of the
+            <a href="https://www.charite.de">Charit&eacute; - Universit&auml;tsmedizin Berlin</a>, the Mouse
+            Informatics Group at the <a href="https://www.sanger.ac.uk/">Sanger Institute</a> and the Smedley group at
+            <a href="https://qmul.ac.uk/whri">Queen Mary University of London</a>.
+        </p>
+
+
+        <p>Problems, suggestions, or comments? Please <a href="mailto:peter.robinson@charite.de">let us know</a></p>
+    </div>
+</div>
+</body>
+</html>
diff --git a/example/exomiser_html_clinical_report/V350145665_L04_B5EHOMdmhwXAAAA-515-exomiser-trio.html b/example/exomiser_html_clinical_report/V350145665_L04_B5EHOMdmhwXAAAA-515-exomiser-trio.html
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@@ -0,0 +1,12976 @@
+<!--
+  ~ The Exomiser - A tool to annotate and prioritize genomic variants
+  ~
+  ~ Copyright (c) 2016-2021 Queen Mary University of London.
+  ~ Copyright (c) 2012-2016 Charité Universitätsmedizin Berlin and Genome Research Ltd.
+  ~
+  ~ This program is free software: you can redistribute it and/or modify
+  ~ it under the terms of the GNU Affero General Public License as
+  ~ published by the Free Software Foundation, either version 3 of the
+  ~ License, or (at your option) any later version.
+  ~
+  ~ This program is distributed in the hope that it will be useful,
+  ~ but WITHOUT ANY WARRANTY; without even the implied warranty of
+  ~ MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
+  ~ GNU Affero General Public License for more details.
+  ~
+  ~ You should have received a copy of the GNU Affero General Public License
+  ~ along with this program.  If not, see <http://www.gnu.org/licenses/>.
+  -->
+
+<!DOCTYPE html>
+
+<html xmlns="http://www.w3.org/1999/xhtml">
+
+<head>
+    <title>The Exomiser - A Tool to Annotate and Prioritise Whole-Exome Sequencing Data</title>
+    <meta charset="UTF-8"/>
+    <meta name="viewport" content="width=device-width, initial-scale=1.0"/>
+    <style>
+        /*!
+ * Bootstrap v3.3.7 (http://getbootstrap.com)
+ * Copyright 2011-2016 Twitter, Inc.
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print{.visible-print{display:block!important}table.visible-print{display:table!important}tr.visible-print{display:table-row!important}td.visible-print,th.visible-print{display:table-cell!important}}.visible-print-block{display:none!important}@media print{.visible-print-block{display:block!important}}.visible-print-inline{display:none!important}@media print{.visible-print-inline{display:inline!important}}.visible-print-inline-block{display:none!important}@media print{.visible-print-inline-block{display:inline-block!important}}@media print{.hidden-print{display:none!important}}
+        /*# sourceMappingURL=bootstrap.min.css.map */
+    </style>
+    <!--<link rel="stylesheet" type="text/css" media="all" href="../../resources/bootstrap-3.2.0/css/bootstrap.min.css" th:href="@{resources/bootstrap-3.2.0/css/bootstrap.min.css}"/>-->
+</head>
+<body>
+<div id="content" class="container">
+    <h2>
+        Exomiser Analysis Results for
+        child
+    </h2>
+    <ul class="nav nav-pills" id="tabs">
+        <li><a href="#settings" role="tab" data-toggle="tab"><b>Analysis Settings</b></a></li>
+        <li><a href="#filtering" role="tab" data-toggle="tab"><b>Filtering Summary</b></a></li>
+        <li><a href="#distribution" role="tab" data-toggle="tab"><b>Variant Type Distribution</b></a></li>
+        <li><a href="#prioritisation" role="tab" data-toggle="tab"><b>Prioritised Genes</b></a></li>
+        
+        <li><a href="#about" role="tab" data-toggle="tab"><b>About</b></a></li>
+    </ul>
+    <div class="panel panel-default" id="settings">
+        <div class="panel-heading">
+            <h3>Analysis Settings</h3>
+        </div>
+        <div class="panel-body"><p>Settings used for this analysis:</p>
+            <pre>---
+sample:
+  genomeAssembly: &quot;hg38&quot;
+  vcf: &quot;/home/ivanwilliamharsono/Downloads/trio_patient/annotated/V350145665_L04_B5EHOMdmhwXAAAA-515-SnpEff-dbSNP-ClinVar-dbNSFP_annotated-deepTrio.vcf.gz&quot;
+  proband: &quot;child&quot;
+  hpoIds:
+  - &quot;HP:0000007&quot;
+  - &quot;HP:0001433&quot;
+  - &quot;HP:0001903&quot;
+  - &quot;HP:0001541&quot;
+  - &quot;HP:0010972&quot;
+  - &quot;HP:0005561&quot;
+  - &quot;HP:0001396&quot;
+  - &quot;HP:0001410&quot;
+  - &quot;HP:0002910&quot;
+  - &quot;HP:0001399&quot;
+  - &quot;HP:0000938&quot;
+  - &quot;HP:0001642&quot;
+  - &quot;HP:0200114&quot;
+  - &quot;HP:0003073&quot;
+  - &quot;HP:0003233&quot;
+  - &quot;HP:0001873&quot;
+  - &quot;HP:0002151&quot;
+  - &quot;HP:0031964&quot;
+  - &quot;HP:0031956&quot;
+  - &quot;HP:0002366&quot;
+  - &quot;HP:0006568&quot;
+  - &quot;HP:0004333&quot;
+  - &quot;HP:0001531&quot;
+  pedigree:
+    persons:
+    - familyId: &quot;1&quot;
+      individualId: &quot;child&quot;
+      paternalId: &quot;father&quot;
+      maternalId: &quot;mother&quot;
+      sex: &quot;MALE&quot;
+      affectedStatus: &quot;AFFECTED&quot;
+    - familyId: &quot;1&quot;
+      individualId: &quot;father&quot;
+      sex: &quot;MALE&quot;
+      affectedStatus: &quot;UNAFFECTED&quot;
+    - familyId: &quot;1&quot;
+      individualId: &quot;mother&quot;
+      sex: &quot;FEMALE&quot;
+      affectedStatus: &quot;UNAFFECTED&quot;
+  sex: &quot;MALE&quot;
+  age: {}
+analysis:
+  inheritanceModes:
+    AUTOSOMAL_RECESSIVE_COMP_HET: 2.0
+    MITOCHONDRIAL: 0.2
+    AUTOSOMAL_RECESSIVE_HOM_ALT: 0.1
+    X_DOMINANT: 0.1
+    AUTOSOMAL_DOMINANT: 0.1
+    X_RECESSIVE_COMP_HET: 2.0
+    X_RECESSIVE_HOM_ALT: 0.1
+  frequencySources:
+  - &quot;THOUSAND_GENOMES&quot;
+  - &quot;TOPMED&quot;
+  - &quot;UK10K&quot;
+  - &quot;ESP_AFRICAN_AMERICAN&quot;
+  - &quot;ESP_EUROPEAN_AMERICAN&quot;
+  - &quot;ESP_ALL&quot;
+  - &quot;EXAC_AFRICAN_INC_AFRICAN_AMERICAN&quot;
+  - &quot;EXAC_AMERICAN&quot;
+  - &quot;EXAC_EAST_ASIAN&quot;
+  - &quot;EXAC_FINNISH&quot;
+  - &quot;EXAC_NON_FINNISH_EUROPEAN&quot;
+  - &quot;EXAC_OTHER&quot;
+  - &quot;EXAC_SOUTH_ASIAN&quot;
+  - &quot;GNOMAD_E_AFR&quot;
+  - &quot;GNOMAD_E_AMR&quot;
+  - &quot;GNOMAD_E_EAS&quot;
+  - &quot;GNOMAD_E_FIN&quot;
+  - &quot;GNOMAD_E_NFE&quot;
+  - &quot;GNOMAD_E_OTH&quot;
+  - &quot;GNOMAD_E_SAS&quot;
+  - &quot;GNOMAD_G_AFR&quot;
+  - &quot;GNOMAD_G_AMR&quot;
+  - &quot;GNOMAD_G_EAS&quot;
+  - &quot;GNOMAD_G_FIN&quot;
+  - &quot;GNOMAD_G_NFE&quot;
+  - &quot;GNOMAD_G_OTH&quot;
+  - &quot;GNOMAD_G_SAS&quot;
+  pathogenicitySources:
+  - &quot;REVEL&quot;
+  - &quot;MVP&quot;
+  steps:
+  - failedVariantFilter: {}
+  - variantEffectFilter:
+      remove:
+      - &quot;CODING_TRANSCRIPT_INTRON_VARIANT&quot;
+      - &quot;FIVE_PRIME_UTR_EXON_VARIANT&quot;
+      - &quot;THREE_PRIME_UTR_EXON_VARIANT&quot;
+      - &quot;FIVE_PRIME_UTR_INTRON_VARIANT&quot;
+      - &quot;THREE_PRIME_UTR_INTRON_VARIANT&quot;
+      - &quot;NON_CODING_TRANSCRIPT_EXON_VARIANT&quot;
+      - &quot;NON_CODING_TRANSCRIPT_INTRON_VARIANT&quot;
+      - &quot;UPSTREAM_GENE_VARIANT&quot;
+      - &quot;DOWNSTREAM_GENE_VARIANT&quot;
+      - &quot;INTERGENIC_VARIANT&quot;
+      - &quot;REGULATORY_REGION_VARIANT&quot;
+  - frequencyFilter:
+      maxFrequency: 2.0
+  - pathogenicityFilter:
+      keepNonPathogenic: true
+  - inheritanceFilter: {}
+  - omimPrioritiser: {}
+  - hiPhivePrioritiser:
+      runParams: &quot;human, mouse, fish, ppi&quot;
+  - phenixPrioritiser: {}
+outputOptions:
+  outputContributingVariantsOnly: true
+  numGenes: 50
+  outputFormats:
+  - &quot;HTML&quot;
+  - &quot;VCF&quot;
+  - &quot;TSV_GENE&quot;
+  - &quot;TSV_VARIANT&quot;
+  - &quot;JSON&quot;
+  outputFileName: &quot;V350145665_L04_B5EHOMdmhwXAAAA-515-exomiser-trio&quot;
+  outputDirectory: &quot;/home/ivanwilliamharsono/Downloads/trio_patient/exomiser&quot;
+</pre>
+        </div>
+    </div>
+
+    <div class="panel panel-default" id="filtering">
+        <div class="panel-heading">
+            <h3>Filtering Summary</h3>
+        </div>
+        <div class="panel-body">
+            <table class="table">
+                <thead>
+                <tr>
+                    <th>Filter</th>
+                    <th>Report</th>
+                    <th>Passed filter</th>
+                    <th>Failed filter</th>
+                </tr>
+                </thead>
+                <tbody>
+                <tr>
+                    <td><b>Failed previous VCF filters</b></td>
+                    <td>
+                        
+                    </td>
+                    <td>124</td>
+                    <td>0</td>
+                </tr>
+                <tr>
+                    <td><b>Variant effect</b></td>
+                    <td>
+                        <ul>Removed variants with effects of type: [CODING_TRANSCRIPT_INTRON_VARIANT, FIVE_PRIME_UTR_EXON_VARIANT, THREE_PRIME_UTR_EXON_VARIANT, FIVE_PRIME_UTR_INTRON_VARIANT, THREE_PRIME_UTR_INTRON_VARIANT, NON_CODING_TRANSCRIPT_EXON_VARIANT, NON_CODING_TRANSCRIPT_INTRON_VARIANT, UPSTREAM_GENE_VARIANT, DOWNSTREAM_GENE_VARIANT, INTERGENIC_VARIANT, REGULATORY_REGION_VARIANT]</ul>
+                    </td>
+                    <td>124</td>
+                    <td>0</td>
+                </tr>
+                <tr>
+                    <td><b>Frequency</b></td>
+                    <td>
+                        <ul>Variants filtered for maximum allele frequency of 2.00%</ul>
+                    </td>
+                    <td>124</td>
+                    <td>0</td>
+                </tr>
+                <tr>
+                    <td><b>Pathogenicity</b></td>
+                    <td>
+                        <ul>Retained all non-pathogenic variants of all types. Scoring was applied, but the filter passed all variants.</ul>
+                    </td>
+                    <td>124</td>
+                    <td>0</td>
+                </tr>
+                <tr>
+                    <td><b>Inheritance</b></td>
+                    <td>
+                        <ul>Genes filtered for compatibility with AUTOSOMAL_DOMINANT, AUTOSOMAL_RECESSIVE, X_RECESSIVE, X_DOMINANT, MITOCHONDRIAL inheritance.</ul>
+                    </td>
+                    <td>66</td>
+                    <td>0</td>
+                </tr>
+                </tbody>
+            </table>
+        </div>
+    </div>
+    <div class="panel panel-default" id="distribution">
+        <div class="panel-heading">
+            <h3>Variant Type Distribution</h3>
+        </div>
+        <div class="panel-body">
+            <table class="table-striped table-condensed">
+                <thead>
+                <tr>
+                    <th>Variant Type</th>
+                    
+                        <th>child</th>
+                    
+                        <th>father</th>
+                    
+                        <th>mother</th>
+                    
+                </tr>
+                </thead>
+                <tbody>
+                <tr>
+                    <td>FRAMESHIFT_ELONGATION</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>FRAMESHIFT_TRUNCATION</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>FRAMESHIFT_VARIANT</td>
+                    
+                        <td>1</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>INTERNAL_FEATURE_ELONGATION</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>FEATURE_TRUNCATION</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>MNV</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>STOP_GAINED</td>
+                    
+                        <td>1</td>
+                    
+                        <td>1</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>STOP_LOST</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>START_LOST</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>SPLICE_ACCEPTOR_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>SPLICE_DONOR_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>MISSENSE_VARIANT</td>
+                    
+                        <td>67</td>
+                    
+                        <td>27</td>
+                    
+                        <td>31</td>
+                    
+                </tr>
+                <tr>
+                    <td>INFRAME_INSERTION</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>DISRUPTIVE_INFRAME_INSERTION</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>INFRAME_DELETION</td>
+                    
+                        <td>1</td>
+                    
+                        <td>0</td>
+                    
+                        <td>1</td>
+                    
+                </tr>
+                <tr>
+                    <td>DISRUPTIVE_INFRAME_DELETION</td>
+                    
+                        <td>2</td>
+                    
+                        <td>0</td>
+                    
+                        <td>1</td>
+                    
+                </tr>
+                <tr>
+                    <td>FIVE_PRIME_UTR_TRUNCATION</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>THREE_PRIME_UTR_TRUNCATION</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>SPLICE_REGION_VARIANT</td>
+                    
+                        <td>12</td>
+                    
+                        <td>7</td>
+                    
+                        <td>6</td>
+                    
+                </tr>
+                <tr>
+                    <td>STOP_RETAINED_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>INITIATOR_CODON_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>SYNONYMOUS_VARIANT</td>
+                    
+                        <td>40</td>
+                    
+                        <td>11</td>
+                    
+                        <td>23</td>
+                    
+                </tr>
+                <tr>
+                    <td>CODING_TRANSCRIPT_INTRON_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>FIVE_PRIME_UTR_EXON_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>THREE_PRIME_UTR_EXON_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>FIVE_PRIME_UTR_INTRON_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>THREE_PRIME_UTR_INTRON_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>NON_CODING_TRANSCRIPT_EXON_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>NON_CODING_TRANSCRIPT_INTRON_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>UPSTREAM_GENE_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>DOWNSTREAM_GENE_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>INTERGENIC_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                <tr>
+                    <td>REGULATORY_REGION_VARIANT</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                        <td>0</td>
+                    
+                </tr>
+                </tbody>
+            </table>
+        </div>
+    </div>
+
+    
+
+    <div class="panel panel-default" id="prioritisation">
+        <div class="panel-heading">
+            <h3>Prioritised Genes</h3>
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="GBE1" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000114480">GBE1</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.931</b>
+                    <data>(p=8.4E-4)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.658</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.985</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.639 to <a href="http://www.omim.org/entry/232500">Glycogen storage disease IV</a> associated with GBE1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0001903, Anemia - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0001541, Ascites - HP:0001541, Ascites</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0001396, Cholestasis - HP:0001399, Hepatic failure</dd><dd>HP:0001410, Decreased liver function - HP:0001399, Hepatic failure</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0001399, Hepatic failure</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001638, Cardiomyopathy</dd><dd>HP:0200114, Metabolic alkalosis - HP:0000969, Edema</dd><dd>HP:0003073, Hypoalbuminemia - HP:0040081, Abnormal circulating creatine kinase concentration</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0040081, Abnormal circulating creatine kinase concentration</dd><dd>HP:0001873, Thrombocytopenia - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0002151, Increased serum lactate - HP:0040081, Abnormal circulating creatine kinase concentration</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001394, Cirrhosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001508, Failure to thrive</dd></dl><dl><dt>Phenotypic similarity 0.658 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=GBE1">GBE1</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0003333, liver fibrosis</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0003333, liver fibrosis</dd><dd>HP:0001410, Decreased liver function - MP:0003333, liver fibrosis</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0003333, liver fibrosis</dd><dd>HP:0001399, Hepatic failure - MP:0003333, liver fibrosis</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - MP:0010090, increased circulating creatine kinase level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0010090, increased circulating creatine kinase level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0003333, liver fibrosis</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0003333, liver fibrosis</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0014074, increased brain glycogen level</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0010400, increased liver glycogen level</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.508 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=GBE1%0DPPP1R3C&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to PPP1R3C</a> and phenotypic similarity 0.604 to mouse mutant of PPP1R3C.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0010398, decreased liver glycogen level</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0010398, decreased liver glycogen level</dd><dd>HP:0001410, Decreased liver function - MP:0010398, decreased liver glycogen level</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0010398, decreased liver glycogen level</dd><dd>HP:0001399, Hepatic failure - MP:0010398, decreased liver glycogen level</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0002833, increased heart weight</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005669, increased circulating leptin level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0005669, increased circulating leptin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0001552, increased circulating triglyceride level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0005669, increased circulating leptin level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0010398, decreased liver glycogen level</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0010398, decreased liver glycogen level</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0010398, decreased liver glycogen level</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 1.57 (p-value: 0.000060)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/232500">OMIM:232500</a> Glycogen storage disease IV - autosomal recessive</dd>
+<dd><a href="http://www.omim.org/entry/263570">OMIM:263570</a> Polyglucosan body disease, adult form - autosomal recessive</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=206583">ORPHA:206583</a> Adult polyglucosan body disease - autosomal recessive</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.931</b>
+                                    <data>(p=8.4E-4)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.658</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.985</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.639 to OMIM:232500 Glycogen storage disease IV</dt>
+                                
+                                    <dt>Phenotypic similarity 0.475 to OMIM:263570 Polyglucosan body disease, adult form</dt>
+                                
+                                    <dt>Phenotypic similarity 0.203 to ORPHA:206583 Adult polyglucosan body disease</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>3-81648954-C-G [1/1:0/1:0/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting, PP3_Moderate, PP4]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.985</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000429644.7">GBE1:ENST00000429644.7:c.593G&gt;C:p.(Arg198Thr)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.9849782</dd>
+                                    
+                                    <dd>REVEL: 0.873</dd>
+                                    <dd>MVP: 0.985</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="MATN2" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000132561">MATN2</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.400</b>
+                    <data>(p=1.3E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.837</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=MATN2%0DTWSG1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to TWSG1</a> and phenotypic similarity 0.633 to mouse mutant of TWSG1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0008479, decreased spleen white pulp amount</dd><dd>HP:0001903, Anemia - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0002398, abnormal bone marrow cell morphology/development</dd><dd>HP:0001396, Cholestasis - MP:0003644, thymus atrophy</dd><dd>HP:0001410, Decreased liver function - MP:0009541, increased thymocyte apoptosis</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0009541, increased thymocyte apoptosis</dd><dd>HP:0001399, Hepatic failure - MP:0009541, increased thymocyte apoptosis</dd><dd>HP:0000938, Osteopenia - MP:0020010, decreased bone mineral density of femur</dd><dd>HP:0001642, Pulmonic stenosis - MP:0001634, internal hemorrhage</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - MP:0003179, thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0009541, increased thymocyte apoptosis</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0009541, increased thymocyte apoptosis</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0031109, subarachnoid hemorrhage</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000704, abnormal thymus development</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0000220, increased monocyte cell number</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001732, postnatal growth retardation</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=MATN2%0DTWSG1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to TWSG1</a> and phenotypic similarity 0.179 to fish mutant of TWSG1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - ZP:0104386, caudal artery increased distribution, abnormal</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.400</b>
+                                    <data>(p=1.3E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.837</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>8-98003762-C-A [0/1:0/0:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs371094213">rs371094213</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.858</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000254898.7">MATN2:ENST00000254898.7:c.1306C&gt;A:p.(Pro436Thr)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.9541492</dd>
+                                    
+                                    <dd>REVEL: 0.282</dd>
+                                    <dd>MVP: 0.954</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>TOPMed: 0.0212%</dd>
+                                    <dd>ExAC AFR: 0.0205%</dd>
+                                    <dd>ExAC EAS: 0.2555%</dd>
+                                    <dd>gnomAD_E_AFR: 0.0131%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0060%</dd>
+                                    <dd>gnomAD_E_EAS: 0.3653%</dd>
+                                    <dd>gnomAD_E_OTH: 0.1096%</dd>
+                                    <dd>gnomAD_G_AMR: 0.1193%</dd>
+                                    <dd>gnomAD_G_EAS: 0.5556%</dd>
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>8-98007571-G-A [0/1:0/1:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs372608950">rs372608950</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4_Moderate]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.816</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000254898.7">MATN2:ENST00000254898.7:c.1543G&gt;A:p.(Val515Met)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.8298366</dd>
+                                    
+                                    <dd>REVEL: 0.122</dd>
+                                    <dd>MVP: 0.830</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>TOPMed: 0.0042%</dd>
+                                    <dd>ExAC FIN: 0.0151%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0030%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0058%</dd>
+                                    <dd>gnomAD_E_FIN: 0.0135%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0018%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0097%</dd>
+                                    <dd>gnomAD_G_AMR: 0.1193%</dd>
+                                    <dd>gnomAD_G_NFE: 0.0067%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="SLC7A10" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000130876">SLC7A10</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.395</b>
+                    <data>(p=1.3E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.502</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.832</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.265 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=SLC7A10">SLC7A10</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001262, decreased body weight</dd></dl><dl><dt>Proximity score 0.502 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=SLC7A10%0DSLC7A7&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SLC7A7</a> and phenotypic similarity 0.789 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=470">Lysinuric protein intolerance</a> associated with SLC7A7.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0001903, Anemia - HP:0001903, Anemia</dd><dd>HP:0001541, Ascites - HP:0002240, Hepatomegaly</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001903, Anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0031020, Bone marrow hypercellularity</dd><dd>HP:0001396, Cholestasis - HP:0001399, Hepatic failure</dd><dd>HP:0001410, Decreased liver function - HP:0001399, Hepatic failure</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0001399, Hepatic failure - HP:0001399, Hepatic failure</dd><dd>HP:0000938, Osteopenia - HP:0000938, Osteopenia</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001627, Abnormal heart morphology</dd><dd>HP:0200114, Metabolic alkalosis - HP:0001987, Hyperammonemia</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003281, Increased circulating ferritin concentration</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003233, Decreased HDL cholesterol concentration</dd><dd>HP:0001873, Thrombocytopenia - HP:0001873, Thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate - HP:0003348, Hyperalaninemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0012280, Hepatic amyloidosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0012156, Hemophagocytosis</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001508, Failure to thrive</dd></dl><dl><dt>Proximity score 0.502 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=SLC7A10%0DSLC7A7&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SLC7A7</a> and phenotypic similarity 0.519 to mouse mutant of SLC7A7.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0004953, decreased spleen weight</dd><dd>HP:0001903, Anemia - MP:0000219, increased neutrophil cell number</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0000219, increased neutrophil cell number</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0005016, decreased lymphocyte cell number</dd><dd>HP:0001396, Cholestasis - MP:0000597, delayed hepatic development</dd><dd>HP:0001410, Decreased liver function - MP:0000597, delayed hepatic development</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000597, delayed hepatic development</dd><dd>HP:0001399, Hepatic failure - MP:0000597, delayed hepatic development</dd><dd>HP:0000938, Osteopenia - MP:0020137, decreased bone mineralization</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - MP:0000219, increased neutrophil cell number</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000597, delayed hepatic development</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000597, delayed hepatic development</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000597, delayed hepatic development</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0000219, increased neutrophil cell number</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0008489, slow postnatal weight gain</dd></dl><dl><dt>Proximity score 0.502 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=SLC7A10%0DSLC7A7&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SLC7A7</a> and phenotypic similarity 0.323 to fish mutant of SLC7A7.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - ZP:0016849, microglia development decreased occurrence, abnormal</dd><dd>HP:0001903, Anemia - ZP:0016849, microglia development decreased occurrence, abnormal</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - ZP:0016849, microglia development decreased occurrence, abnormal</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - ZP:0016849, microglia development decreased occurrence, abnormal</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - ZP:0016849, microglia development decreased occurrence, abnormal</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - ZP:0016849, microglia development decreased occurrence, abnormal</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - ZP:0016849, microglia development decreased occurrence, abnormal</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.395</b>
+                                    <data>(p=1.3E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.502</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.832</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>19-33215803-C-T [0/1:0/1:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs567938130">rs567938130</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.895</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000253188.8">SLC7A10:ENST00000253188.8:c.322G&gt;A:p.(Ala108Thr)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.9017956</dd>
+                                    
+                                    <dd>REVEL: 0.401</dd>
+                                    <dd>MVP: 0.902</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0312%</dd>
+                                    <dd>TOPMed: 0.0110%</dd>
+                                    <dd>ExAC NFE: 0.0535%</dd>
+                                    <dd>ExAC SAS: 0.0247%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0112%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0162%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0056%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0164%</dd>
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SPLICE_REGION_VARIANT</span>
+                            <b>SNV</b>
+                            <b>19-33210906-T-C [0/1:0/0:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs375747229">rs375747229</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.770</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000253188.8">SLC7A10:ENST00000253188.8:c.1017-8A&gt;G:p.?</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0625%</dd>
+                                    <dd>TOPMed: 0.0068%</dd>
+                                    <dd>ExAC AFR: 0.0108%</dd>
+                                    <dd>ExAC EAS: 0.2005%</dd>
+                                    <dd>ExAC SAS: 0.0621%</dd>
+                                    <dd>gnomAD_E_EAS: 0.1803%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0184%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0455%</dd>
+                                    <dd>gnomAD_G_EAS: 0.2469%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="MUC12" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000205277">MUC12</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.336</b>
+                    <data>(p=1.5E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.506</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.800</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Proximity score 0.506 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=MUC12%0DGALNT1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to GALNT1</a> and phenotypic similarity 0.745 to mouse mutant of GALNT1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0001903, Anemia - MP:0002607, decreased basophil cell number</dd><dd>HP:0001541, Ascites - MP:0005606, increased bleeding time</dd><dd>HP:0010972, Anemia of inadequate production - MP:0005012, decreased eosinophil cell number</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0002607, decreased basophil cell number</dd><dd>HP:0001396, Cholestasis - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0001410, Decreased liver function - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0001399, Hepatic failure - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0006128, pulmonary valve stenosis</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - MP:0005419, decreased circulating serum albumin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0005419, decreased circulating serum albumin level</dd><dd>HP:0001873, Thrombocytopenia - MP:0002607, decreased basophil cell number</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0010470, dilated ascending aorta</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.336</b>
+                                    <data>(p=1.5E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.506</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.800</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SPLICE_REGION_VARIANT</span>
+                            <b>SNV</b>
+                            <b>7-100969688-A-G [0/1:./.:./.]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs73168328">rs73168328</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.800</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000536621.6">MUC12:ENST00000536621.6:c.66A&gt;G:p.(=)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.017</b>
+                                    <data>(p=4.5E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.506</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.433</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SPLICE_REGION_VARIANT</span>
+                            <b>SNV</b>
+                            <b>7-100969688-A-G [0/1:./.:./.]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs73168328">rs73168328</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.800</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000536621.6">MUC12:ENST00000536621.6:c.66A&gt;G:p.(=)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>7-100991252-A-C [0/1:0/0:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs759776287">rs759776287</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4_Strong]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.066</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000536621.6">MUC12:ENST00000536621.6:c.689A&gt;C:p.(Tyr230Ser)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.06665444</dd>
+                                    
+                                    <dd>REVEL: 0.014</dd>
+                                    <dd>MVP: 0.067</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>gnomAD_E_AFR: 0.0260%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0042%</dd>
+                                    <dd>gnomAD_G_AFR: 0.0115%</dd>
+                                    <dd>gnomAD_G_NFE: 0.0067%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="KDM5A" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000073614">KDM5A</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.327</b>
+                    <data>(p=1.6E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.502</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.800</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.334 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=KDM5A">KDM5A</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0002123, abnormal definitive hematopoiesis</dd><dd>HP:0001903, Anemia - MP:0002123, abnormal definitive hematopoiesis</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0002123, abnormal definitive hematopoiesis</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0000219, increased neutrophil cell number</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - MP:0000219, increased neutrophil cell number</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0000219, increased neutrophil cell number</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.502 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=KDM5A%0DARID4A&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to ARID4A</a> and phenotypic similarity 0.667 to mouse mutant of ARID4A.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000599, enlarged liver</dd><dd>HP:0001903, Anemia - MP:0001577, anemia</dd><dd>HP:0001541, Ascites - MP:0000599, enlarged liver</dd><dd>HP:0010972, Anemia of inadequate production - MP:0002445, abnormal mononuclear cell differentiation</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0011747, myelofibrosis</dd><dd>HP:0001396, Cholestasis - MP:0000599, enlarged liver</dd><dd>HP:0001410, Decreased liver function - MP:0000599, enlarged liver</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000599, enlarged liver</dd><dd>HP:0001399, Hepatic failure - MP:0000599, enlarged liver</dd><dd>HP:0000938, Osteopenia - MP:0002397, abnormal bone marrow morphology</dd><dd>HP:0001642, Pulmonic stenosis - MP:0004834, ovary hemorrhage</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - MP:0003179, thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000599, enlarged liver</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000599, enlarged liver</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000599, enlarged liver</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0000223, decreased monocyte cell number</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.327</b>
+                                    <data>(p=1.6E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.502</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.800</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SPLICE_REGION_VARIANT</span>
+                            <b>INS</b>
+                            <b>12-323210-C-CA [0/1:./.:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs60377454">rs60377454</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.800</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000399788.7">KDM5A:ENST00000399788.7:c.2151-5_2151-4insT:p.?</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="LRRK2" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000188906">LRRK2</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.291</b>
+                    <data>(p=1.7E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.512</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.771</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.296 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=411602">Hereditary late-onset Parkinson disease</a> associated with LRRK2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - HP:0002171, Gliosis</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0004926, Orthostatic hypotension due to autonomic dysfunction</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0002171, Gliosis</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001824, Weight loss</dd></dl><dl><dt>Phenotypic similarity 0.278 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=LRRK2">LRRK2</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia - MP:0008918, microgliosis</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0008918, microgliosis</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0008918, microgliosis</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - MP:0008918, microgliosis</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0008918, microgliosis</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0008918, microgliosis</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.251 to zebrafish mutant involving <a href="http://zfin.org/action/quicksearch/query?query=LRRK2">LRRK2</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - ZP:0019952, otic vesicle edematous, abnormal</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - ZP:0019959, spinal cord has fewer parts of type neuron, abnormal</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.512 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=LRRK2%0DLRRK1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to LRRK1</a> and phenotypic similarity 0.419 to <a href="http://www.omim.org/entry/615198">Osteosclerotic metaphyseal dysplasia</a> associated with LRRK1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0011001, Increased bone mineral density</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0003155, Elevated circulating alkaline phosphatase concentration</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia - HP:0011001, Increased bone mineral density</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003155, Elevated circulating alkaline phosphatase concentration</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003155, Elevated circulating alkaline phosphatase concentration</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0003155, Elevated circulating alkaline phosphatase concentration</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0003155, Elevated circulating alkaline phosphatase concentration</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001508, Failure to thrive</dd></dl><dl><dt>Proximity score 0.512 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=LRRK2%0DLRRK1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to LRRK1</a> and phenotypic similarity 0.631 to mouse mutant of LRRK1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0005012, decreased eosinophil cell number</dd><dd>HP:0001903, Anemia - MP:0010067, increased red blood cell distribution width</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0005012, decreased eosinophil cell number</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0000221, decreased leukocyte cell number</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function - MP:0002966, decreased circulating alkaline phosphatase level</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0002966, decreased circulating alkaline phosphatase level</dd><dd>HP:0001399, Hepatic failure - MP:0002966, decreased circulating alkaline phosphatase level</dd><dd>HP:0000938, Osteopenia - MP:0000062, increased bone mineral density</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005343, increased circulating aspartate transaminase level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0010090, increased circulating creatine kinase level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0001556, increased circulating HDL cholesterol level</dd><dd>HP:0001873, Thrombocytopenia - MP:0003179, thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate - MP:0005343, increased circulating aspartate transaminase level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0002966, decreased circulating alkaline phosphatase level</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0002966, decreased circulating alkaline phosphatase level</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0000219, increased neutrophil cell number</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0002764, short tibia</dd></dl><dl><dt>PhenIX semantic similarity score: 0.46 (p-value: 0.605260)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/607060">OMIM:607060</a> Parkinson disease 8 (susceptibility)</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=2828">ORPHA:2828</a> Young-onset Parkinson disease - autosomal recessive</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=411602">ORPHA:411602</a> Hereditary late-onset Parkinson disease - autosomal dominant</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.291</b>
+                                    <data>(p=1.7E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.512</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.771</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.158 to ORPHA:2828 Young-onset Parkinson disease</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SPLICE_REGION_VARIANT</span>
+                            <b>SNV</b>
+                            <b>12-40315306-T-A [0/1:0/0:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs550610903">rs550610903</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP6]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=787873%5Balleleid%5D">(criteria provided, single submitter)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.787</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000298910.12">LRRK2:ENST00000298910.12:c.4827+6T&gt;A:p.?</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0156%</dd>
+                                    <dd>TOPMed: 0.0156%</dd>
+                                    <dd>ExAC EAS: 0.0809%</dd>
+                                    <dd>ExAC SAS: 0.0121%</dd>
+                                    <dd>gnomAD_E_EAS: 0.1102%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0009%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0065%</dd>
+                                    <dd>gnomAD_G_EAS: 0.0621%</dd>
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>12-40295498-A-G [0/1:0/1:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs573263484">rs573263484</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[PM2_Supporting, BP4_Moderate]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.754</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000298910.12">LRRK2:ENST00000298910.12:c.2950A&gt;G:p.(Ile984Val)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.75450885</dd>
+                                    
+                                    <dd>REVEL: 0.135</dd>
+                                    <dd>MVP: 0.755</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>ExAC NFE: 0.0015%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0027%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="SPDYE5" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000170092">SPDYE5</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.249</b>
+                    <data>(p=1.9E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.289</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>1.000</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.289 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=SPDYE5">SPDYE5</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000689, abnormal spleen morphology</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0000689, abnormal spleen morphology</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0000689, abnormal spleen morphology</dd><dd>HP:0001410, Decreased liver function - MP:0000689, abnormal spleen morphology</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000689, abnormal spleen morphology</dd><dd>HP:0001399, Hepatic failure - MP:0000689, abnormal spleen morphology</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000689, abnormal spleen morphology</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000689, abnormal spleen morphology</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000689, abnormal spleen morphology</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.249</b>
+                                    <data>(p=1.9E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.289</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>1.000</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">FRAMESHIFT_VARIANT</span>
+                            <b>DEL</b>
+                            <b>7-75497938-AG-A [0/1:0/0:0/0]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 1.000</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000625065.4">SPDYE5:ENST00000625065.4:c.613del:p.(Asp205Ilefs*14)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="MYO7A" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000137474">MYO7A</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.248</b>
+                    <data>(p=1.9E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.511</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.747</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.431 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=MYO7A">MYO7A</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0010123, increased bone mineral content</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia - MP:0000063, decreased bone mineral density</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001262, decreased body weight</dd></dl><dl><dt>Phenotypic similarity 0.169 to zebrafish mutant involving <a href="http://zfin.org/action/quicksearch/query?query=MYO7A">MYO7A</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - ZP:0010818, inner ear receptor cell stereocilium organization disrupted, abnormal</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.511 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=MYO7A%0DWHRN&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to WHRN</a> and phenotypic similarity 0.613 to mouse mutant of WHRN.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0002981, increased liver weight</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - MP:0002981, increased liver weight</dd><dd>HP:0010972, Anemia of inadequate production - MP:0000221, decreased leukocyte cell number</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0000221, decreased leukocyte cell number</dd><dd>HP:0001396, Cholestasis - MP:0002981, increased liver weight</dd><dd>HP:0001410, Decreased liver function - MP:0010398, decreased liver glycogen level</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0010398, decreased liver glycogen level</dd><dd>HP:0001399, Hepatic failure - MP:0010398, decreased liver glycogen level</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0002833, increased heart weight</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0001745, increased circulating corticosterone level</dd><dd>HP:0001873, Thrombocytopenia - MP:0000221, decreased leukocyte cell number</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0010398, decreased liver glycogen level</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0010398, decreased liver glycogen level</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0004362, cochlear hair cell degeneration</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0010398, decreased liver glycogen level</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0000221, decreased leukocyte cell number</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001262, decreased body weight</dd></dl><dl><dt>PhenIX semantic similarity score: 0.08 (p-value: 0.999990)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/276900">OMIM:276900</a> Usher syndrome, type 1B - autosomal recessive</dd>
+<dd><a href="http://www.omim.org/entry/600060">OMIM:600060</a> Deafness, autosomal recessive 2 - autosomal recessive</dd>
+<dd><a href="http://www.omim.org/entry/601317">OMIM:601317</a> Deafness, autosomal dominant 11 - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=231169">ORPHA:231169</a> Usher syndrome type 1 - autosomal recessive</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=231178">ORPHA:231178</a> Usher syndrome type 2 - autosomal recessive</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.248</b>
+                                    <data>(p=1.9E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.511</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.747</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>11-77199723-A-G [0/1:0/0:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs201251963">rs201251963</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                
+                                
+                                
+                                
+                                <span class="label label-default">CONFLICTING_PATHOGENICITY_INTERPRETATIONS</span>
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=194096%5Balleleid%5D">(criteria provided, conflicting interpretations)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.755</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000409709.9">MYO7A:ENST00000409709.9:c.4757A&gt;G:p.(Asn1586Ser)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.82669157</dd>
+                                    
+                                    <dd>REVEL: 0.320</dd>
+                                    <dd>MVP: 0.827</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0468%</dd>
+                                    <dd>TOPMed: 0.0336%</dd>
+                                    <dd>UK10K: 0.0132%</dd>
+                                    <dd>ESP AA: 0.1230%</dd>
+                                    <dd>ESP All: 0.0401%</dd>
+                                    <dd>ExAC AFR: 0.0432%</dd>
+                                    <dd>ExAC AMR: 0.0176%</dd>
+                                    <dd>ExAC EAS: 0.4086%</dd>
+                                    <dd>ExAC OTH: 0.2326%</dd>
+                                    <dd>ExAC SAS: 0.0063%</dd>
+                                    <dd>gnomAD_E_AFR: 0.0527%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0149%</dd>
+                                    <dd>gnomAD_E_EAS: 0.4931%</dd>
+                                    <dd>gnomAD_E_OTH: 0.1098%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0098%</dd>
+                                    <dd>gnomAD_G_AFR: 0.1032%</dd>
+                                    <dd>gnomAD_G_EAS: 0.4321%</dd>
+                                    <dd>gnomAD_G_OTH: 0.1022%</dd>
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>11-77204123-G-A [0/1:0/1:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs369424114">rs369424114</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4, BP6]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=738306%5Balleleid%5D">(criteria provided, single submitter)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.739</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000409709.9">MYO7A:ENST00000409709.9:c.5374G&gt;A:p.(Val1792Ile)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.78195363</dd>
+                                    
+                                    <dd>REVEL: 0.254</dd>
+                                    <dd>MVP: 0.782</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0937%</dd>
+                                    <dd>TOPMed: 0.0042%</dd>
+                                    <dd>ESP EA: 0.0119%</dd>
+                                    <dd>ESP All: 0.0080%</dd>
+                                    <dd>ExAC AFR: 0.0233%</dd>
+                                    <dd>ExAC EAS: 0.0949%</dd>
+                                    <dd>ExAC NFE: 0.0033%</dd>
+                                    <dd>ExAC SAS: 0.3376%</dd>
+                                    <dd>gnomAD_E_AFR: 0.0078%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0639%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0010%</dd>
+                                    <dd>gnomAD_E_SAS: 0.2198%</dd>
+                                    <dd>gnomAD_G_NFE: 0.0067%</dd>
+                                    <dd>gnomAD_G_OTH: 0.1020%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="CYP11B2" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000179142">CYP11B2</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.133</b>
+                    <data>(p=2.6E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.506</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.670</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.439 to <a href="http://www.omim.org/entry/610600">Hypoaldosteronism, congenital, due to CMO II deficiency</a> associated with CYP11B2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0020200, Increased circulating 18-hydroxycortisone level</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - HP:0001944, Dehydration</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0020200, Increased circulating 18-hydroxycortisone level</dd><dd>HP:0001410, Decreased liver function - HP:0004319, Decreased circulating aldosterone level</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0004319, Decreased circulating aldosterone level</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001278, Orthostatic hypotension</dd><dd>HP:0200114, Metabolic alkalosis - HP:0000848, Increased circulating renin level</dd><dd>HP:0003073, Hypoalbuminemia - HP:0000848, Increased circulating renin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0004319, Decreased circulating aldosterone level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0000848, Increased circulating renin level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0001278, Orthostatic hypotension</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0004319, Decreased circulating aldosterone level</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001508, Failure to thrive</dd></dl><dl><dt>Phenotypic similarity 0.481 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=CYP11B2">CYP11B2</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0002981, increased liver weight</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - MP:0002981, increased liver weight</dd><dd>HP:0010972, Anemia of inadequate production - MP:0004956, decreased thymus weight</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0002981, increased liver weight</dd><dd>HP:0001410, Decreased liver function - MP:0002981, increased liver weight</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0002981, increased liver weight</dd><dd>HP:0001399, Hepatic failure - MP:0002981, increased liver weight</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0006144, increased systemic arterial systolic blood pressure</dd><dd>HP:0200114, Metabolic alkalosis - MP:0001748, increased circulating adrenocorticotropin level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0003353, decreased circulating renin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0002665, decreased circulating corticosterone level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0001748, increased circulating adrenocorticotropin level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0002981, increased liver weight</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0002981, increased liver weight</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0002176, increased brain weight</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0002981, increased liver weight</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.506 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=CYP11B2%0DAKR1D1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to AKR1D1</a> and phenotypic similarity 0.716 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=79303">Congenital bile acid synthesis defect type 2</a> associated with AKR1D1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0002240, Hepatomegaly</dd><dd>HP:0001903, Anemia - HP:0001978, Extramedullary hematopoiesis</dd><dd>HP:0001541, Ascites - HP:0002240, Hepatomegaly</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001978, Extramedullary hematopoiesis</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001978, Extramedullary hematopoiesis</dd><dd>HP:0001396, Cholestasis - HP:0001396, Cholestasis</dd><dd>HP:0001410, Decreased liver function - HP:0001399, Hepatic failure</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0001399, Hepatic failure - HP:0001399, Hepatic failure</dd><dd>HP:0000938, Osteopenia - HP:0002748, Rickets</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - HP:0030984, Abnormal serum bile acid concentration</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003155, Elevated circulating alkaline phosphatase concentration</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0030984, Abnormal serum bile acid concentration</dd><dd>HP:0001873, Thrombocytopenia - HP:0001978, Extramedullary hematopoiesis</dd><dd>HP:0002151, Increased serum lactate - HP:0030984, Abnormal serum bile acid concentration</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001397, Hepatic steatosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001978, Extramedullary hematopoiesis</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001508, Failure to thrive</dd></dl><dl><dt>Proximity score 0.506 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=CYP11B2%0DAKR1D1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to AKR1D1</a> and phenotypic similarity 0.183 to mouse mutant of AKR1D1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0002833, increased heart weight</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0002833, increased heart weight</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0013278, decreased fasting circulating glucose level</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.92 (p-value: 0.093620)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/203400">OMIM:203400</a> Hypoaldosteronism, congenital, due to CMO I deficiency - autosomal recessive</dd>
+<dd><a href="http://www.omim.org/entry/610600">OMIM:610600</a> Hypoaldosteronism, congenital, due to CMO II deficiency - autosomal recessive</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=403">ORPHA:403</a> Familial hyperaldosteronism type I (unconfirmed)</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.133</b>
+                                    <data>(p=2.6E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.506</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.670</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.439 to OMIM:610600 Hypoaldosteronism, congenital, due to CMO II deficiency</dt>
+                                
+                                    <dt>Phenotypic similarity 0.430 to OMIM:203400 Hypoaldosteronism, congenital, due to CMO I deficiency</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>8-142917102-C-T [1/1:0/1:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs372556807">rs372556807</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                
+                                
+                                
+                                
+                                <span class="label label-default">CONFLICTING_PATHOGENICITY_INTERPRETATIONS</span>
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=313362%5Balleleid%5D">(criteria provided, conflicting interpretations)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.670</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000323110.2">CYP11B2:ENST00000323110.2:c.352G&gt;A:p.(Ala118Thr)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.67928296</dd>
+                                    
+                                    <dd>REVEL: 0.285</dd>
+                                    <dd>MVP: 0.679</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0312%</dd>
+                                    <dd>TOPMed: 0.0034%</dd>
+                                    <dd>ExAC EAS: 0.0925%</dd>
+                                    <dd>ExAC SAS: 0.0061%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0754%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0182%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0097%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="NPHS1" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000161270">NPHS1</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.065</b>
+                    <data>(p=3.3E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.570</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.511</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.570 to <a href="http://www.omim.org/entry/256300">Nephrotic syndrome, type 1</a> associated with NPHS1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0003270, Abdominal distention</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - HP:0000969, Edema</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0000821, Hypothyroidism</dd><dd>HP:0001410, Decreased liver function - HP:0000821, Hypothyroidism</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0000821, Hypothyroidism</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - HP:0000969, Edema</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003073, Hypoalbuminemia</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003077, Hyperlipidemia</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0003075, Hypoproteinemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0000821, Hypothyroidism</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001518, Small for gestational age</dd></dl><dl><dt>Phenotypic similarity 0.313 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=NPHS1">NPHS1</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0003068, enlarged kidney</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - MP:0001785, edema</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002962, increased urine protein level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0002962, increased urine protein level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.219 to zebrafish mutant involving <a href="http://zfin.org/action/quicksearch/query?query=NPHS1">NPHS1</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - ZP:0010821, yolk syncytial layer edematous, abnormal</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - ZP:0010898, pronephric glomerular capillary hypotrophic, abnormal</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.504 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=NPHS1%0DCD2AP&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to CD2AP</a> and phenotypic similarity 0.529 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=656">Genetic steroid-resistant nephrotic syndrome</a> associated with CD2AP.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0002586, Peritonitis</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - HP:0000969, Edema</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0002586, Peritonitis</dd><dd>HP:0001410, Decreased liver function - HP:0002586, Peritonitis</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0002586, Peritonitis</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - HP:0000969, Edema</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003073, Hypoalbuminemia</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003073, Hypoalbuminemia</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0003073, Hypoalbuminemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0002586, Peritonitis</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.504 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=NPHS1%0DCD2AP&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to CD2AP</a> and phenotypic similarity 0.676 to mouse mutant of CD2AP.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0003643, spleen atrophy</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - MP:0005324, ascites</dd><dd>HP:0010972, Anemia of inadequate production - MP:0003643, spleen atrophy</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0003644, thymus atrophy</dd><dd>HP:0001410, Decreased liver function - MP:0003644, thymus atrophy</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0003644, thymus atrophy</dd><dd>HP:0001399, Hepatic failure - MP:0003644, thymus atrophy</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0000274, enlarged heart</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005553, increased circulating creatinine level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0005419, decreased circulating serum albumin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0005419, decreased circulating serum albumin level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0005553, increased circulating creatinine level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0003644, thymus atrophy</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0003644, thymus atrophy</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0003644, thymus atrophy</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0005264, glomerulosclerosis</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001732, postnatal growth retardation</dd></dl><dl><dt>Proximity score 0.504 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=NPHS1%0DCD2AP&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to CD2AP</a> and phenotypic similarity 0.210 to fish mutant of CD2AP.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - ZP:0002202, whole organism edematous, abnormal</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - ZP:0018769, pronephric glomerular capillary distended, abnormal</dd><dd>HP:0001531, Failure to thrive in infancy - ZP:0002202, whole organism edematous, abnormal</dd></dl><dl><dt>PhenIX semantic similarity score: 0.84 (p-value: 0.016680)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/256300">OMIM:256300</a> Nephrotic syndrome, type 1 - autosomal recessive</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=656">ORPHA:656</a> Genetic steroid-resistant nephrotic syndrome - autosomal dominant/recessive</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=839">ORPHA:839</a> Congenital nephrotic syndrome, Finnish type - autosomal recessive</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.065</b>
+                                    <data>(p=3.3E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.570</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.511</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.570 to OMIM:256300 Nephrotic syndrome, type 1</dt>
+                                
+                                    <dt>Phenotypic similarity 0.529 to ORPHA:656 Genetic steroid-resistant nephrotic syndrome</dt>
+                                
+                                    <dt>Phenotypic similarity 0.291 to ORPHA:839 Congenital nephrotic syndrome, Finnish type</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SPLICE_REGION_VARIANT</span>
+                            <b>SNV</b>
+                            <b>19-35844248-G-A [0/1:0/1:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs1973103431">rs1973103431</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[PM2_Supporting, BP6_Strong]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=1148728%5Balleleid%5D">(criteria provided, multiple submitters, no conflicts)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.800</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000378910.10">NPHS1:ENST00000378910.10:c.2072-5C&gt;T:p.?</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>TOPMed: 0.0004%</dd>
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>19-35849273-C-T [0/1:0/0:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs115308424">rs115308424</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4_Moderate, BP6_Strong]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    <span class="label label-success">BENIGN</span>
+                                
+                                
+                                
+                                
+                                
+                                
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=741816%5Balleleid%5D">(criteria provided, multiple submitters, no conflicts)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.222</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000378910.10">NPHS1:ENST00000378910.10:c.803G&gt;A:p.(Arg268Gln)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.35008886</dd>
+                                    
+                                    <dd>REVEL: 0.132</dd>
+                                    <dd>MVP: 0.350</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.6402%</dd>
+                                    <dd>TOPMed: 0.0771%</dd>
+                                    <dd>ESP AA: 0.0681%</dd>
+                                    <dd>ESP All: 0.0231%</dd>
+                                    <dd>ExAC AFR: 0.0405%</dd>
+                                    <dd>ExAC AMR: 0.0087%</dd>
+                                    <dd>ExAC EAS: 1.2050%</dd>
+                                    <dd>ExAC NFE: 0.0046%</dd>
+                                    <dd>ExAC OTH: 0.3401%</dd>
+                                    <dd>ExAC SAS: 0.2926%</dd>
+                                    <dd>gnomAD_E_AFR: 0.0332%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0119%</dd>
+                                    <dd>gnomAD_E_EAS: 1.3077%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0027%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0916%</dd>
+                                    <dd>gnomAD_E_SAS: 0.2665%</dd>
+                                    <dd>gnomAD_G_AFR: 0.0574%</dd>
+                                    <dd>gnomAD_G_EAS: 0.9889%</dd>
+                                    <dd>gnomAD_G_NFE: 0.0067%</dd>
+                                    <dd>gnomAD_G_OTH: 0.1018%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+                <div class="row">
+                    <div class="col-sm-12">
+                        <b>Other passed variants:</b>
+                    </div>
+                </div>
+                
+                
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                        <b>SNV</b>
+                        <b>19-35851580-G-A [0/1:0/0:0/1]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs114385015">rs114385015</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    <div class="col-sm-12">
+                        <b>ClinVar: </b>
+                        
+                        
+                            
+                            
+                            
+                            
+                            
+                            <span class="label label-default">CONFLICTING_PATHOGENICITY_INTERPRETATIONS</span>
+                            <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=348619%5Balleleid%5D">(criteria provided, conflicting interpretations)</a>
+                        
+                    </div>
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.074</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000378910.10">NPHS1:ENST00000378910.10:c.151C&gt;T:p.(=)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            
+                            <dd>1000Genomes: 0.6402%</dd>
+                            <dd>TOPMed: 0.0801%</dd>
+                            <dd>ESP AA: 0.0908%</dd>
+                            <dd>ESP EA: 0.0349%</dd>
+                            <dd>ESP All: 0.0539%</dd>
+                            <dd>ExAC AFR: 0.0218%</dd>
+                            <dd>ExAC AMR: 0.0267%</dd>
+                            <dd>ExAC EAS: 1.0331%</dd>
+                            <dd>ExAC NFE: 0.0158%</dd>
+                            <dd>ExAC OTH: 0.3606%</dd>
+                            <dd>ExAC SAS: 0.2790%</dd>
+                            <dd>gnomAD_E_AFR: 0.0200%</dd>
+                            <dd>gnomAD_E_AMR: 0.0388%</dd>
+                            <dd>gnomAD_E_EAS: 1.0627%</dd>
+                            <dd>gnomAD_E_NFE: 0.0185%</dd>
+                            <dd>gnomAD_E_OTH: 0.0920%</dd>
+                            <dd>gnomAD_E_SAS: 0.2601%</dd>
+                            <dd>gnomAD_G_AFR: 0.0688%</dd>
+                            <dd>gnomAD_G_EAS: 0.7398%</dd>
+                            <dd>gnomAD_G_NFE: 0.0133%</dd>
+                            <dd>gnomAD_G_OTH: 0.1020%</dd>
+                        </dl>
+                    </div>
+                </div>
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="KRT6B" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000185479">KRT6B</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.040</b>
+                    <data>(p=3.7E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.181</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.895</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.337 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=2309">Pachyonychia congenita</a> associated with KRT6B.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - HP:0007490, Linear arrays of macular hyperkeratoses in flexural areas</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001508, Failure to thrive</dd></dl><dl><dt>Phenotypic similarity 0.362 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=KRT6B">KRT6B</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001732, postnatal growth retardation</dd></dl><dl><dt>PhenIX semantic similarity score: 0.64 (p-value: 0.157600)</dt></dl><dl>
+<dt>Known diseases - observed variants incompatible with mode of inheritance:</dt>
+<dd><a href="http://www.omim.org/entry/615728">OMIM:615728</a> Pachyonychia congenita 4 - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=2309">ORPHA:2309</a> Pachyonychia congenita - autosomal dominant</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.040</b>
+                                    <data>(p=3.7E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.181</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.895</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>12-52449543-C-T [1/1:0/1:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs369853484">rs369853484</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.895</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000252252.4">KRT6B:ENST00000252252.4:c.1003G&gt;A:p.(Ala335Thr)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.9026787</dd>
+                                    
+                                    <dd>REVEL: 0.420</dd>
+                                    <dd>MVP: 0.903</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>ESP EA: 0.0116%</dd>
+                                    <dd>ESP All: 0.0077%</dd>
+                                    <dd>ExAC SAS: 0.0606%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0058%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0552%</dd>
+                                    <dd>gnomAD_G_EAS: 0.0619%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="URB2" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000135763">URB2</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.039</b>
+                    <data>(p=3.8E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.531</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.301 to zebrafish mutant involving <a href="http://zfin.org/action/quicksearch/query?query=URB2">URB2</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - ZP:0018768, thymus absent, abnormal</dd><dd>HP:0001903, Anemia - ZP:0018768, thymus absent, abnormal</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - ZP:0018768, thymus absent, abnormal</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - ZP:0018768, thymus absent, abnormal</dd><dd>HP:0001396, Cholestasis - ZP:0018768, thymus absent, abnormal</dd><dd>HP:0001410, Decreased liver function - ZP:0018768, thymus absent, abnormal</dd><dd>HP:0002910, Elevated hepatic transaminase - ZP:0018768, thymus absent, abnormal</dd><dd>HP:0001399, Hepatic failure - ZP:0018768, thymus absent, abnormal</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - ZP:0018768, thymus absent, abnormal</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - ZP:0018768, thymus absent, abnormal</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - ZP:0018768, thymus absent, abnormal</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - ZP:0018768, thymus absent, abnormal</dd><dd>HP:0004333, Bone-marrow foam cells - ZP:0018768, thymus absent, abnormal</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=URB2%0DIRS1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to IRS1</a> and phenotypic similarity 0.258 to <a href="http://www.omim.org/entry/125853">Type 2 diabetes mellitus, susceptibility to</a> associated with IRS1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0005978, Type II diabetes mellitus</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0005978, Type II diabetes mellitus</dd><dd>HP:0001410, Decreased liver function - HP:0005978, Type II diabetes mellitus</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0005978, Type II diabetes mellitus</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - HP:0000855, Insulin resistance</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0000855, Insulin resistance</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0005978, Type II diabetes mellitus</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0031819, Increased waist to hip ratio</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=URB2%0DIRS1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to IRS1</a> and phenotypic similarity 0.638 to mouse mutant of IRS1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0008396, abnormal osteoclast differentiation</dd><dd>HP:0001903, Anemia - MP:0008396, abnormal osteoclast differentiation</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0008396, abnormal osteoclast differentiation</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0004989, decreased osteoblast cell number</dd><dd>HP:0001396, Cholestasis - MP:0003059, decreased insulin secretion</dd><dd>HP:0001410, Decreased liver function - MP:0003059, decreased insulin secretion</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0003059, decreased insulin secretion</dd><dd>HP:0001399, Hepatic failure - MP:0003059, decreased insulin secretion</dd><dd>HP:0000938, Osteopenia - MP:0000063, decreased bone mineral density</dd><dd>HP:0001642, Pulmonic stenosis - MP:0006143, increased systemic arterial diastolic blood pressure</dd><dd>HP:0200114, Metabolic alkalosis - MP:0002079, increased circulating insulin level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002079, increased circulating insulin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0000186, decreased circulating HDL cholesterol level</dd><dd>HP:0001873, Thrombocytopenia - MP:0008396, abnormal osteoclast differentiation</dd><dd>HP:0002151, Increased serum lactate - MP:0001554, increased circulating free fatty acids level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0003059, decreased insulin secretion</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0003059, decreased insulin secretion</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0003059, decreased insulin secretion</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0008396, abnormal osteoclast differentiation</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001262, decreased body weight</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=URB2%0DIRS1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to IRS1</a> and phenotypic similarity 0.300 to fish mutant of IRS1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - ZP:0005798, developmental growth decreased rate, abnormal</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.039</b>
+                                    <data>(p=3.8E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.531</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>1-229635178-A-C [0/1:0/1:0/0]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.613</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000258243.7">URB2:ENST00000258243.7:c.565A&gt;C:p.(Asn189His)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.61290497</dd>
+                                    
+                                    <dd>REVEL: 0.365</dd>
+                                    <dd>MVP: 0.613</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>1-229647556-T-C [0/1:0/0:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs371627284">rs371627284</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4_Moderate]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.449</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000258243.7">URB2:ENST00000258243.7:c.3953T&gt;C:p.(Val1318Ala)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.4515046</dd>
+                                    
+                                    <dd>REVEL: 0.110</dd>
+                                    <dd>MVP: 0.452</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0156%</dd>
+                                    <dd>TOPMed: 0.0079%</dd>
+                                    <dd>ExAC AFR: 0.0192%</dd>
+                                    <dd>ExAC EAS: 0.0116%</dd>
+                                    <dd>ExAC SAS: 0.0242%</dd>
+                                    <dd>gnomAD_E_AFR: 0.0196%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0030%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0232%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0182%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0162%</dd>
+                                    <dd>gnomAD_G_AFR: 0.0344%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="OR10G9" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000236981">OR10G9</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.034</b>
+                    <data>(p=3.9E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.517</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=OR10G9%0DMEFV&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to MEFV</a> and phenotypic similarity 0.588 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=342">Familial Mediterranean fever</a> associated with MEFV.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001744, Splenomegaly</dd><dd>HP:0001903, Anemia - HP:0002716, Lymphadenopathy</dd><dd>HP:0001541, Ascites - HP:0001541, Ascites</dd><dd>HP:0010972, Anemia of inadequate production - HP:0002716, Lymphadenopathy</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0002716, Lymphadenopathy</dd><dd>HP:0001396, Cholestasis - HP:0006554, Acute hepatic failure</dd><dd>HP:0001410, Decreased liver function - HP:0006554, Acute hepatic failure</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0006554, Acute hepatic failure</dd><dd>HP:0000938, Osteopenia - HP:0001369, Arthritis</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001658, Myocardial infarction</dd><dd>HP:0200114, Metabolic alkalosis - HP:0001945, Fever</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - HP:0002716, Lymphadenopathy</dd><dd>HP:0002151, Increased serum lactate - HP:0001945, Fever</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0006554, Acute hepatic failure</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0002633, Vasculitis</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=OR10G9%0DMEFV&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to MEFV</a> and phenotypic similarity 0.616 to mouse mutant of MEFV.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000691, enlarged spleen</dd><dd>HP:0001903, Anemia - MP:0001577, anemia</dd><dd>HP:0001541, Ascites - MP:0000691, enlarged spleen</dd><dd>HP:0010972, Anemia of inadequate production - MP:0001577, anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0000218, increased leukocyte cell number</dd><dd>HP:0001396, Cholestasis - MP:0001860, liver inflammation</dd><dd>HP:0001410, Decreased liver function - MP:0001860, liver inflammation</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0001860, liver inflammation</dd><dd>HP:0001399, Hepatic failure - MP:0001860, liver inflammation</dd><dd>HP:0000938, Osteopenia - MP:0002933, joint inflammation</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0008553, increased circulating tumor necrosis factor level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0008553, increased circulating tumor necrosis factor level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0008553, increased circulating tumor necrosis factor level</dd><dd>HP:0001873, Thrombocytopenia - MP:0000322, increased granulocyte number</dd><dd>HP:0002151, Increased serum lactate - MP:0008553, increased circulating tumor necrosis factor level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0001860, liver inflammation</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0001860, liver inflammation</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0001860, liver inflammation</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0005425, increased macrophage cell number</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001732, postnatal growth retardation</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.034</b>
+                                    <data>(p=3.9E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.517</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>11-124023707-G-C [0/1:0/1:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs767983467">rs767983467</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4_Moderate]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.720</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000375024.1">OR10G9:ENST00000375024.1:c.695G&gt;C:p.(Gly232Ala)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.7209725</dd>
+                                    
+                                    <dd>REVEL: 0.126</dd>
+                                    <dd>MVP: 0.721</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>ExAC EAS: 0.0116%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0116%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0032%</dd>
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>11-124023083-C-G [0/1:0/0:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs113347250">rs113347250</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4_Moderate]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.313</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000375024.1">OR10G9:ENST00000375024.1:c.71C&gt;G:p.(Pro24Arg)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.44500792</dd>
+                                    
+                                    <dd>REVEL: 0.076</dd>
+                                    <dd>MVP: 0.445</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.4841%</dd>
+                                    <dd>TOPMed: 0.3234%</dd>
+                                    <dd>ESP AA: 1.1586%</dd>
+                                    <dd>ESP All: 0.3923%</dd>
+                                    <dd>ExAC AFR: 1.0475%</dd>
+                                    <dd>ExAC AMR: 0.0518%</dd>
+                                    <dd>ExAC SAS: 0.1757%</dd>
+                                    <dd>gnomAD_E_AFR: 0.9344%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0744%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0365%</dd>
+                                    <dd>gnomAD_E_SAS: 0.1819%</dd>
+                                    <dd>gnomAD_G_AFR: 0.8722%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+                <div class="row">
+                    <div class="col-sm-12">
+                        <b>Other passed variants:</b>
+                    </div>
+                </div>
+                
+                
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                        <b>SNV</b>
+                        <b>11-124023660-T-C [0/1:0/0:0/1]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs141129525">rs141129525</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.096</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000375024.1">OR10G9:ENST00000375024.1:c.648T&gt;C:p.(=)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            
+                            <dd>1000Genomes: 0.1093%</dd>
+                            <dd>TOPMed: 0.0672%</dd>
+                            <dd>ESP AA: 0.0909%</dd>
+                            <dd>ESP All: 0.0308%</dd>
+                            <dd>ExAC AFR: 0.1345%</dd>
+                            <dd>ExAC AMR: 0.0518%</dd>
+                            <dd>ExAC EAS: 0.0578%</dd>
+                            <dd>ExAC NFE: 0.0150%</dd>
+                            <dd>gnomAD_E_AFR: 0.1438%</dd>
+                            <dd>gnomAD_E_AMR: 0.0387%</dd>
+                            <dd>gnomAD_E_EAS: 0.0522%</dd>
+                            <dd>gnomAD_E_FIN: 0.0045%</dd>
+                            <dd>gnomAD_E_NFE: 0.0099%</dd>
+                            <dd>gnomAD_E_SAS: 0.0032%</dd>
+                            <dd>gnomAD_G_AFR: 0.2522%</dd>
+                            <dd>gnomAD_G_EAS: 0.1233%</dd>
+                            <dd>gnomAD_G_NFE: 0.0067%</dd>
+                        </dl>
+                    </div>
+                </div>
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">MISSENSE_VARIANT</span>
+                        <b>SNV</b>
+                        <b>11-124023543-G-C [0/1:0/0:0/1]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs200638744">rs200638744</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.095</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000375024.1">OR10G9:ENST00000375024.1:c.531G&gt;C:p.(Leu177Phe)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            <dd>Best Score: 0.13424169</dd>
+                            
+                            <dd>REVEL: 0.076</dd>
+                            <dd>MVP: 0.134</dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            
+                            <dd>1000Genomes: 0.4060%</dd>
+                            <dd>gnomAD_E_AFR: 0.0131%</dd>
+                            <dd>gnomAD_E_AMR: 0.0417%</dd>
+                            <dd>gnomAD_E_EAS: 0.0232%</dd>
+                            <dd>gnomAD_E_FIN: 0.0090%</dd>
+                            <dd>gnomAD_E_NFE: 0.0090%</dd>
+                            <dd>gnomAD_E_OTH: 0.1463%</dd>
+                            <dd>gnomAD_E_SAS: 1.1439%</dd>
+                            <dd>gnomAD_G_AFR: 0.0229%</dd>
+                            <dd>gnomAD_G_FIN: 0.0286%</dd>
+                            <dd>gnomAD_G_NFE: 0.0267%</dd>
+                            <dd>gnomAD_G_OTH: 0.3055%</dd>
+                        </dl>
+                    </div>
+                </div>
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                        <b>SNV</b>
+                        <b>11-124023210-C-T [0/1:0/0:0/1]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs112152472">rs112152472</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.080</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000375024.1">OR10G9:ENST00000375024.1:c.198C&gt;T:p.(=)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            
+                            <dd>1000Genomes: 0.4841%</dd>
+                            <dd>TOPMed: 0.3230%</dd>
+                            <dd>ESP AA: 0.8636%</dd>
+                            <dd>ESP All: 0.2933%</dd>
+                            <dd>gnomAD_E_AFR: 0.9017%</dd>
+                            <dd>gnomAD_E_AMR: 0.0747%</dd>
+                            <dd>gnomAD_E_OTH: 0.0369%</dd>
+                            <dd>gnomAD_E_SAS: 0.1760%</dd>
+                            <dd>gnomAD_G_AFR: 0.8601%</dd>
+                        </dl>
+                    </div>
+                </div>
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                        <b>SNV</b>
+                        <b>11-124023540-T-C [0/1:0/0:0/1]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs569353053">rs569353053</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.068</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000375024.1">OR10G9:ENST00000375024.1:c.528T&gt;C:p.(=)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            
+                            <dd>1000Genomes: 0.4060%</dd>
+                            <dd>gnomAD_E_AFR: 0.0065%</dd>
+                            <dd>gnomAD_E_AMR: 0.0387%</dd>
+                            <dd>gnomAD_E_EAS: 0.0232%</dd>
+                            <dd>gnomAD_E_FIN: 0.0090%</dd>
+                            <dd>gnomAD_E_NFE: 0.0081%</dd>
+                            <dd>gnomAD_E_OTH: 0.1645%</dd>
+                            <dd>gnomAD_E_SAS: 1.2120%</dd>
+                            <dd>gnomAD_G_AFR: 0.0229%</dd>
+                            <dd>gnomAD_G_FIN: 0.0286%</dd>
+                            <dd>gnomAD_G_NFE: 0.0267%</dd>
+                            <dd>gnomAD_G_OTH: 0.3055%</dd>
+                        </dl>
+                    </div>
+                </div>
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                        <b>SNV</b>
+                        <b>11-124023549-T-C [0/1:0/0:0/1]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs2924497">rs2924497</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.050</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000375024.1">OR10G9:ENST00000375024.1:c.537T&gt;C:p.(=)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            
+                            <dd>1000Genomes: 0.4528%</dd>
+                            <dd>TOPMed: 0.0884%</dd>
+                            <dd>gnomAD_E_AFR: 0.0327%</dd>
+                            <dd>gnomAD_E_AMR: 0.0834%</dd>
+                            <dd>gnomAD_E_EAS: 0.0232%</dd>
+                            <dd>gnomAD_E_FIN: 0.0224%</dd>
+                            <dd>gnomAD_E_NFE: 0.0772%</dd>
+                            <dd>gnomAD_E_OTH: 0.1828%</dd>
+                            <dd>gnomAD_E_SAS: 1.5457%</dd>
+                            <dd>gnomAD_G_AFR: 0.0459%</dd>
+                            <dd>gnomAD_G_AMR: 0.1196%</dd>
+                            <dd>gnomAD_G_EAS: 0.0617%</dd>
+                            <dd>gnomAD_G_FIN: 0.0572%</dd>
+                            <dd>gnomAD_G_NFE: 0.0533%</dd>
+                            <dd>gnomAD_G_OTH: 0.4073%</dd>
+                        </dl>
+                    </div>
+                </div>
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="KRT2" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000172867">KRT2</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.034</b>
+                    <data>(p=3.9E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.250</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.799</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.250 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=455">Superficial epidermolytic ichthyosis</a> associated with KRT2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - HP:0000969, Edema</dd><dd>HP:0010972, Anemia of inadequate production - HP:0008064, Ichthyosis</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - HP:0000969, Edema</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0000969, Edema</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.267 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=KRT2">KRT2</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - MP:0002796, impaired skin barrier function</dd><dd>HP:0010972, Anemia of inadequate production - MP:0002656, abnormal keratinocyte differentiation</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=KRT2%0DCYP27A1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to CYP27A1</a> and phenotypic similarity 0.616 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=909">Cerebrotendinous xanthomatosis</a> associated with CYP27A1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001081, Cholelithiasis</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - HP:0002171, Gliosis</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0002659, Increased susceptibility to fractures</dd><dd>HP:0001396, Cholestasis - HP:0006579, Prolonged neonatal jaundice</dd><dd>HP:0001410, Decreased liver function - HP:0000821, Hypothyroidism</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0012379, Abnormal circulating enzyme concentration or activity</dd><dd>HP:0001399, Hepatic failure - HP:0000821, Hypothyroidism</dd><dd>HP:0000938, Osteopenia - HP:0000938, Osteopenia</dd><dd>HP:0001642, Pulmonic stenosis - HP:0011994, Abnormal atrial septum morphology</dd><dd>HP:0200114, Metabolic alkalosis - HP:0002151, Increased serum lactate</dd><dd>HP:0003073, Hypoalbuminemia - HP:0002151, Increased serum lactate</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0002151, Increased serum lactate</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0002151, Increased serum lactate</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0012379, Abnormal circulating enzyme concentration or activity</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0012379, Abnormal circulating enzyme concentration or activity</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0002196, Myelopathy</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001081, Cholelithiasis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0004416, Precocious atherosclerosis</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=KRT2%0DCYP27A1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to CYP27A1</a> and phenotypic similarity 0.632 to mouse mutant of CYP27A1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0002981, increased liver weight</dd><dd>HP:0001903, Anemia - MP:0008935, decreased mean platelet volume</dd><dd>HP:0001541, Ascites - MP:0002981, increased liver weight</dd><dd>HP:0010972, Anemia of inadequate production - MP:0008935, decreased mean platelet volume</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0002981, increased liver weight</dd><dd>HP:0001410, Decreased liver function - MP:0002981, increased liver weight</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0002981, increased liver weight</dd><dd>HP:0001399, Hepatic failure - MP:0002981, increased liver weight</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0000266, abnormal heart morphology</dd><dd>HP:0200114, Metabolic alkalosis - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0000186, decreased circulating HDL cholesterol level</dd><dd>HP:0001873, Thrombocytopenia - MP:0008935, decreased mean platelet volume</dd><dd>HP:0002151, Increased serum lactate - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0002981, increased liver weight</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0002981, increased liver weight</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0002981, increased liver weight</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0008935, decreased mean platelet volume</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.17 (p-value: 0.683470)</dt></dl><dl>
+<dt>Known diseases - observed variants incompatible with mode of inheritance:</dt>
+<dd><a href="http://www.omim.org/entry/146800">OMIM:146800</a> Ichthyosis bullosa of Siemens - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=455">ORPHA:455</a> Superficial epidermolytic ichthyosis - autosomal dominant</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.034</b>
+                                    <data>(p=3.9E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.250</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.799</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SPLICE_REGION_VARIANT</span>
+                            <b>SNV</b>
+                            <b>12-52647860-T-C [1/1:0/1:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs1354217118">rs1354217118</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.799</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000309680.4">KRT2:ENST00000309680.4:c.1123-5A&gt;G:p.?</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>gnomAD_E_EAS: 0.0058%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="CIP2A" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000163507">CIP2A</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.033</b>
+                    <data>(p=3.9E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.512</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=CIP2A%0DPOU2AF1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to POU2AF1</a> and phenotypic similarity 0.679 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=186">Primary biliary cholangitis</a> associated with POU2AF1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001409, Portal hypertension</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - HP:0001541, Ascites</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0000939, Osteoporosis</dd><dd>HP:0001396, Cholestasis - HP:0000952, Jaundice</dd><dd>HP:0001410, Decreased liver function - HP:0001399, Hepatic failure</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0003155, Elevated circulating alkaline phosphatase concentration</dd><dd>HP:0001399, Hepatic failure - HP:0001399, Hepatic failure</dd><dd>HP:0000938, Osteopenia - HP:0000939, Osteoporosis</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001278, Orthostatic hypotension</dd><dd>HP:0200114, Metabolic alkalosis - HP:0002908, Conjugated hyperbilirubinemia</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003073, Hypoalbuminemia</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003119, Abnormal circulating lipid concentration</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0002908, Conjugated hyperbilirubinemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0003155, Elevated circulating alkaline phosphatase concentration</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0003155, Elevated circulating alkaline phosphatase concentration</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0001278, Orthostatic hypotension</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001395, Hepatic fibrosis</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=CIP2A%0DPOU2AF1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to POU2AF1</a> and phenotypic similarity 0.390 to mouse mutant of POU2AF1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0008474, absent spleen germinal center</dd><dd>HP:0001903, Anemia - MP:0002144, abnormal B cell differentiation</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0002144, abnormal B cell differentiation</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0002144, abnormal B cell differentiation</dd><dd>HP:0001396, Cholestasis - MP:0008474, absent spleen germinal center</dd><dd>HP:0001410, Decreased liver function - MP:0008474, absent spleen germinal center</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0008474, absent spleen germinal center</dd><dd>HP:0001399, Hepatic failure - MP:0008474, absent spleen germinal center</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - MP:0005017, decreased B cell number</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0008474, absent spleen germinal center</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0008474, absent spleen germinal center</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0008474, absent spleen germinal center</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0002144, abnormal B cell differentiation</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001262, decreased body weight</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.033</b>
+                                    <data>(p=3.9E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.512</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>3-108560707-T-C [0/1:0/0:0/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[PM2_Supporting, BP4_Moderate]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.566</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000295746.13">CIP2A:ENST00000295746.13:c.1769A&gt;G:p.(Asp590Gly)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.5658299</dd>
+                                    
+                                    <dd>REVEL: 0.029</dd>
+                                    <dd>MVP: 0.566</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>3-108560731-T-A [0/1:0/1:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs147916833">rs147916833</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4_Moderate]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.457</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000295746.13">CIP2A:ENST00000295746.13:c.1745A&gt;T:p.(Lys582Met)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.5657933</dd>
+                                    
+                                    <dd>REVEL: 0.082</dd>
+                                    <dd>MVP: 0.566</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.1093%</dd>
+                                    <dd>TOPMed: 0.1093%</dd>
+                                    <dd>ESP AA: 0.0227%</dd>
+                                    <dd>ESP All: 0.0077%</dd>
+                                    <dd>ExAC AFR: 0.0096%</dd>
+                                    <dd>ExAC EAS: 0.7518%</dd>
+                                    <dd>gnomAD_E_AFR: 0.0065%</dd>
+                                    <dd>gnomAD_E_EAS: 0.8827%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0183%</dd>
+                                    <dd>gnomAD_G_AFR: 0.0344%</dd>
+                                    <dd>gnomAD_G_EAS: 0.7481%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="RAB3A" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000105649">RAB3A</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.023</b>
+                    <data>(p=4.2E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.521</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.450</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Proximity score 0.521 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=RAB3A%0DRAB3GAP2&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to RAB3GAP2</a> and phenotypic similarity 0.246 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=2510">Micro syndrome</a> associated with RAB3GAP2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0000823, Delayed puberty</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001339, Lissencephaly</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0000823, Delayed puberty</dd><dd>HP:0001410, Decreased liver function - HP:0000823, Delayed puberty</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0000823, Delayed puberty</dd><dd>HP:0000938, Osteopenia - HP:0001387, Joint stiffness</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0009830, Peripheral neuropathy</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0000823, Delayed puberty</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.521 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=RAB3A%0DRAB3GAP2&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to RAB3GAP2</a> and phenotypic similarity 0.601 to mouse mutant of RAB3GAP2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia - MP:0000208, decreased hematocrit</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0000208, decreased hematocrit</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0001399, Hepatic failure - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0005333, decreased heart rate</dd><dd>HP:0200114, Metabolic alkalosis - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0000186, decreased circulating HDL cholesterol level</dd><dd>HP:0001873, Thrombocytopenia - MP:0003179, thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate - MP:0005344, increased circulating bilirubin level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0008259, abnormal optic disk morphology</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0003179, thrombocytopenia</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.023</b>
+                                    <data>(p=4.2E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.521</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.450</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SPLICE_REGION_VARIANT</span>
+                            <b>SNV</b>
+                            <b>19-18198852-A-G [0/1:0/1:0/0]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.800</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000222256.9">RAB3A:ENST00000222256.9:c.348-3T&gt;C:p.?</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                            <b>SNV</b>
+                            <b>19-18197593-C-T [0/1:0/0:0/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.100</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000222256.9">RAB3A:ENST00000222256.9:c.540G&gt;A:p.(=)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="TIAM1" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000156299">TIAM1</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.023</b>
+                    <data>(p=4.2E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.507</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.465</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.298 to <a href="http://www.omim.org/entry/619908">Neurodevelopmental disorder with language delay and seizures</a> associated with TIAM1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0000821, Hypothyroidism</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - HP:0003429, CNS hypomyelination</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0000821, Hypothyroidism</dd><dd>HP:0001410, Decreased liver function - HP:0000821, Hypothyroidism</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0000821, Hypothyroidism</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001629, Ventricular septal defect</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - HP:0002917, Hypomagnesemia</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0002917, Hypomagnesemia</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0002917, Hypomagnesemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0003429, CNS hypomyelination</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0000821, Hypothyroidism</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.192 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=TIAM1">TIAM1</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0000783, abnormal forebrain morphology</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.507 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=TIAM1%0DANK1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to ANK1</a> and phenotypic similarity 0.546 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=822">Hereditary spherocytosis</a> associated with ANK1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001744, Splenomegaly</dd><dd>HP:0001903, Anemia - HP:0001903, Anemia</dd><dd>HP:0001541, Ascites - HP:0003270, Abdominal distention</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001978, Extramedullary hematopoiesis</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001978, Extramedullary hematopoiesis</dd><dd>HP:0001396, Cholestasis - HP:0000952, Jaundice</dd><dd>HP:0001410, Decreased liver function - HP:0001081, Cholelithiasis</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0001081, Cholelithiasis</dd><dd>HP:0000938, Osteopenia - HP:0001997, Gout</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001723, Restrictive cardiomyopathy</dd><dd>HP:0200114, Metabolic alkalosis - HP:0001945, Fever</dd><dd>HP:0003073, Hypoalbuminemia - HP:0002904, Hyperbilirubinemia</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0002904, Hyperbilirubinemia</dd><dd>HP:0001873, Thrombocytopenia - HP:0004444, Spherocytosis</dd><dd>HP:0002151, Increased serum lactate - HP:0002904, Hyperbilirubinemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0002240, Hepatomegaly</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001903, Anemia</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.507 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=TIAM1%0DANK1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to ANK1</a> and phenotypic similarity 0.765 to mouse mutant of ANK1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000599, enlarged liver</dd><dd>HP:0001903, Anemia - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0001541, Ascites - MP:0000599, enlarged liver</dd><dd>HP:0010972, Anemia of inadequate production - MP:0008387, hypochromic anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0002397, abnormal bone marrow morphology</dd><dd>HP:0001396, Cholestasis - MP:0000611, jaundice</dd><dd>HP:0001410, Decreased liver function - MP:0000611, jaundice</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000611, jaundice</dd><dd>HP:0001399, Hepatic failure - MP:0000611, jaundice</dd><dd>HP:0000938, Osteopenia - MP:0002397, abnormal bone marrow morphology</dd><dd>HP:0001642, Pulmonic stenosis - MP:0001625, cardiac hypertrophy</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005637, abnormal iron homeostasis</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002874, decreased hemoglobin content</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0002874, decreased hemoglobin content</dd><dd>HP:0001873, Thrombocytopenia - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0002151, Increased serum lactate - MP:0005637, abnormal iron homeostasis</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000611, jaundice</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000611, jaundice</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0000876, Purkinje cell degeneration</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000599, enlarged liver</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0000218, increased leukocyte cell number</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/619908">OMIM:619908</a> Neurodevelopmental disorder with language delay and seizures - autosomal recessive</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.023</b>
+                                    <data>(p=4.2E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.507</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.465</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.298 to OMIM:619908 Neurodevelopmental disorder with language delay and seizures</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>21-31135955-C-G [0/1:0/0:0/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[PM2_Supporting, BP4_Moderate]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.583</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000541036.6">TIAM1:ENST00000541036.6:c.3861G&gt;C:p.(Lys1287Asn)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.583064</dd>
+                                    
+                                    <dd>REVEL: 0.165</dd>
+                                    <dd>MVP: 0.583</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>21-31165060-T-A [0/1:0/1:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs373619112">rs373619112</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4_Moderate]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.348</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000541036.6">TIAM1:ENST00000541036.6:c.2893A&gt;T:p.(Ser965Cys)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.35421845</dd>
+                                    
+                                    <dd>REVEL: 0.061</dd>
+                                    <dd>MVP: 0.354</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.1093%</dd>
+                                    <dd>TOPMed: 0.0155%</dd>
+                                    <dd>ExAC AFR: 0.0290%</dd>
+                                    <dd>ExAC EAS: 0.1276%</dd>
+                                    <dd>ExAC SAS: 0.0366%</dd>
+                                    <dd>gnomAD_E_AFR: 0.0392%</dd>
+                                    <dd>gnomAD_E_EAS: 0.1102%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0009%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0183%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0357%</dd>
+                                    <dd>gnomAD_G_AFR: 0.0115%</dd>
+                                    <dd>gnomAD_G_EAS: 0.1233%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="KRT72" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000170486">KRT72</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.019</b>
+                    <data>(p=4.4E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.394</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.571</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.394 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=KRT72">KRT72</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000689, abnormal spleen morphology</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0000689, abnormal spleen morphology</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0000598, abnormal liver morphology</dd><dd>HP:0001410, Decreased liver function - MP:0000598, abnormal liver morphology</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000598, abnormal liver morphology</dd><dd>HP:0001399, Hepatic failure - MP:0000598, abnormal liver morphology</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000598, abnormal liver morphology</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000598, abnormal liver morphology</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000598, abnormal liver morphology</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.019</b>
+                                    <data>(p=4.4E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.394</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.571</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>12-52591508-C-T [1/1:0/1:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs747007532">rs747007532</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.571</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000293745.7">KRT72:ENST00000293745.7:c.919G&gt;A:p.(Ala307Thr)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.5721736</dd>
+                                    
+                                    <dd>REVEL: 0.365</dd>
+                                    <dd>MVP: 0.572</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>ExAC EAS: 0.0116%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0060%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0058%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0018%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="CT45A6" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000278289">CT45A6</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.018</b>
+                    <data>(p=4.5E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.365</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.600</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.365 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=CT45A6">CT45A6</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - MP:0001556, increased circulating HDL cholesterol level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0001556, increased circulating HDL cholesterol level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>X_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.018</b>
+                                    <data>(p=4.5E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.365</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.600</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>X-135798830-T-G [1/1:0/0:./.]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs1556582560">rs1556582560</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.600</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000620654.2">CT45A6:ENST00000620654.2:c.164A&gt;C:p.(Glu55Ala)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>X_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.018</b>
+                                    <data>(p=4.5E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.365</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.600</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>X-135798830-T-G [1/1:0/0:./.]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs1556582560">rs1556582560</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.600</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000620654.2">CT45A6:ENST00000620654.2:c.164A&gt;C:p.(Glu55Ala)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="DNAH5" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000039139">DNAH5</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.015</b>
+                    <data>(p=4.7E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.422</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.341 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=244">Primary ciliary dyskinesia</a> associated with DNAH5.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001746, Asplenia</dd><dd>HP:0001903, Anemia - HP:0001746, Asplenia</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001746, Asplenia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001746, Asplenia</dd><dd>HP:0001396, Cholestasis - HP:0001746, Asplenia</dd><dd>HP:0001410, Decreased liver function - HP:0001746, Asplenia</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0001746, Asplenia</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001627, Abnormal heart morphology</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - HP:0001746, Asplenia</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001746, Asplenia</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001669, Transposition of the great arteries</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.445 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=DNAH5">DNAH5</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000689, abnormal spleen morphology</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0000689, abnormal spleen morphology</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0000598, abnormal liver morphology</dd><dd>HP:0001410, Decreased liver function - MP:0000598, abnormal liver morphology</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000598, abnormal liver morphology</dd><dd>HP:0001399, Hepatic failure - MP:0000598, abnormal liver morphology</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0010607, common atrioventricular valve</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000598, abnormal liver morphology</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000598, abnormal liver morphology</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0001891, hydrocephaly</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000598, abnormal liver morphology</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0004113, abnormal aortic arch morphology</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=DNAH5%0DALMS1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to ALMS1</a> and phenotypic similarity 0.691 to <a href="http://www.omim.org/entry/203800">Alstrom syndrome</a> associated with ALMS1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0002240, Hepatomegaly</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - HP:0002240, Hepatomegaly</dd><dd>HP:0010972, Anemia of inadequate production - HP:0000956, Acanthosis nigricans</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0002240, Hepatomegaly</dd><dd>HP:0001410, Decreased liver function - HP:0000821, Hypothyroidism</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0001399, Hepatic failure - HP:0000821, Hypothyroidism</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001644, Dilated cardiomyopathy</dd><dd>HP:0200114, Metabolic alkalosis - HP:0000842, Hyperinsulinemia</dd><dd>HP:0003073, Hypoalbuminemia - HP:0000842, Hyperinsulinemia</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003233, Decreased HDL cholesterol concentration</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0000842, Hyperinsulinemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001397, Hepatic steatosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0002621, Atherosclerosis</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001956, Truncal obesity</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=DNAH5%0DALMS1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to ALMS1</a> and phenotypic similarity 0.519 to mouse mutant of ALMS1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0002981, increased liver weight</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - MP:0002981, increased liver weight</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0002981, increased liver weight</dd><dd>HP:0001410, Decreased liver function - MP:0031115, macrovesicular hepatic steatosis</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0031115, macrovesicular hepatic steatosis</dd><dd>HP:0001399, Hepatic failure - MP:0031115, macrovesicular hepatic steatosis</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0002079, increased circulating insulin level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002079, increased circulating insulin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0005178, increased circulating cholesterol level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0002079, increased circulating insulin level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0031115, macrovesicular hepatic steatosis</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0031115, macrovesicular hepatic steatosis</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0011967, increased or absent threshold for auditory brainstem response</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0031115, macrovesicular hepatic steatosis</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001260, increased body weight</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=DNAH5%0DALMS1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to ALMS1</a> and phenotypic similarity 0.279 to fish mutant of ALMS1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - ZP:0012993, endocrine pancreas morphology, abnormal</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - ZP:0001192, heart edematous, abnormal</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - ZP:0012993, endocrine pancreas morphology, abnormal</dd><dd>HP:0001410, Decreased liver function - ZP:0012993, endocrine pancreas morphology, abnormal</dd><dd>HP:0002910, Elevated hepatic transaminase - ZP:0012993, endocrine pancreas morphology, abnormal</dd><dd>HP:0001399, Hepatic failure - ZP:0012993, endocrine pancreas morphology, abnormal</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - ZP:0005415, cardiac ventricle morphology, abnormal</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - ZP:0012993, endocrine pancreas morphology, abnormal</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - ZP:0012993, endocrine pancreas morphology, abnormal</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - ZP:0012993, endocrine pancreas morphology, abnormal</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.15 (p-value: 0.605320)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/608644">OMIM:608644</a> Ciliary dyskinesia, primary, 3, with or without situs inversus - autosomal recessive</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=244">ORPHA:244</a> Primary ciliary dyskinesia - autosomal recessive</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.015</b>
+                                    <data>(p=4.7E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.422</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.341 to ORPHA:244 Primary ciliary dyskinesia</dt>
+                                
+                                    <dt>Phenotypic similarity 0.147 to OMIM:608644 Ciliary dyskinesia, primary, 3, with or without situs inversus</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>5-13793636-C-G [0/1:0/0:0/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.744</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000265104.5">DNAH5:ENST00000265104.5:c.8103G&gt;C:p.(Gln2701His)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.74420047</dd>
+                                    
+                                    <dd>REVEL: 0.313</dd>
+                                    <dd>MVP: 0.744</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                            <b>SNV</b>
+                            <b>5-13922230-C-T [0/1:0/1:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs370805321">rs370805321</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP6_Strong]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=683707%5Balleleid%5D">(criteria provided, multiple submitters, no conflicts)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.099</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000265104.5">DNAH5:ENST00000265104.5:c.537G&gt;A:p.(=)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>TOPMed: 0.0117%</dd>
+                                    <dd>ExAC AFR: 0.0096%</dd>
+                                    <dd>ExAC EAS: 0.0583%</dd>
+                                    <dd>ExAC NFE: 0.0030%</dd>
+                                    <dd>gnomAD_E_AFR: 0.0196%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0060%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0756%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0054%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0547%</dd>
+                                    <dd>gnomAD_G_AFR: 0.0229%</dd>
+                                    <dd>gnomAD_G_NFE: 0.0067%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="BTN2A2" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000124508">BTN2A2</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.014</b>
+                    <data>(p=4.7E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.420</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=BTN2A2%0DHSPG2&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to HSPG2</a> and phenotypic similarity 0.507 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=1606">1p36 deletion syndrome</a> associated with HSPG2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001743, Abnormality of the spleen</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0000902, Rib fusion</dd><dd>HP:0001396, Cholestasis - HP:0001392, Abnormality of the liver</dd><dd>HP:0001410, Decreased liver function - HP:0001392, Abnormality of the liver</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0001392, Abnormality of the liver</dd><dd>HP:0000938, Osteopenia - HP:0000902, Rib fusion</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001636, Tetralogy of Fallot</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0001397, Hepatic steatosis</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0003416, Spinal canal stenosis</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001397, Hepatic steatosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0005113, Aortic arch aneurysm</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001508, Failure to thrive</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=BTN2A2%0DHSPG2&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to HSPG2</a> and phenotypic similarity 0.609 to mouse mutant of HSPG2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000602, dilated liver sinusoidal space</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - MP:0005244, hemopericardium</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0000065, abnormal bone marrow cavity morphology</dd><dd>HP:0001396, Cholestasis - MP:0000602, dilated liver sinusoidal space</dd><dd>HP:0001410, Decreased liver function - MP:0000602, dilated liver sinusoidal space</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000602, dilated liver sinusoidal space</dd><dd>HP:0001399, Hepatic failure - MP:0000602, dilated liver sinusoidal space</dd><dd>HP:0000938, Osteopenia - MP:0008272, abnormal endochondral bone ossification</dd><dd>HP:0001642, Pulmonic stenosis - MP:0002748, abnormal pulmonary valve morphology</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000602, dilated liver sinusoidal space</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000602, dilated liver sinusoidal space</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0002152, abnormal brain morphology</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000602, dilated liver sinusoidal space</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0010472, abnormal ascending aorta and coronary artery attachment</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0000547, short limbs</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=BTN2A2%0DHSPG2&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to HSPG2</a> and phenotypic similarity 0.222 to fish mutant of HSPG2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - ZP:0000038, pericardium edematous, abnormal</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - ZP:0006851, cardiac ventricle elongated, abnormal</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - ZP:0000530, dorsal aorta collapsed, abnormal</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.014</b>
+                                    <data>(p=4.7E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.420</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>6-26392785-G-A [0/1:0/0:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs375693447">rs375693447</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.539</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000356709.9">BTN2A2:ENST00000356709.9:c.1390G&gt;A:p.(Asp464Asn)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.55155087</dd>
+                                    
+                                    <dd>REVEL: 0.238</dd>
+                                    <dd>MVP: 0.552</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>TOPMed: 0.0053%</dd>
+                                    <dd>ExAC EAS: 0.1502%</dd>
+                                    <dd>ExAC NFE: 0.0015%</dd>
+                                    <dd>gnomAD_E_EAS: 0.1391%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0009%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0032%</dd>
+                                    <dd>gnomAD_G_EAS: 0.0617%</dd>
+                                    <dd>gnomAD_G_OTH: 0.1020%</dd>
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>6-26392596-C-G [0/1:0/1:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs148562624">rs148562624</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4_Moderate]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.300</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000356709.9">BTN2A2:ENST00000356709.9:c.1201C&gt;G:p.(His401Asp)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.3529108</dd>
+                                    
+                                    <dd>REVEL: 0.132</dd>
+                                    <dd>MVP: 0.353</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0799%</dd>
+                                    <dd>TOPMed: 0.0389%</dd>
+                                    <dd>ESP AA: 0.0227%</dd>
+                                    <dd>ESP All: 0.0077%</dd>
+                                    <dd>ExAC AFR: 0.0384%</dd>
+                                    <dd>ExAC AMR: 0.0259%</dd>
+                                    <dd>ExAC EAS: 0.3932%</dd>
+                                    <dd>ExAC FIN: 0.0302%</dd>
+                                    <dd>ExAC NFE: 0.0015%</dd>
+                                    <dd>ExAC OTH: 0.2203%</dd>
+                                    <dd>ExAC SAS: 0.0485%</dd>
+                                    <dd>gnomAD_E_AFR: 0.0457%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0119%</dd>
+                                    <dd>gnomAD_E_EAS: 0.4874%</dd>
+                                    <dd>gnomAD_E_FIN: 0.0224%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0054%</dd>
+                                    <dd>gnomAD_E_OTH: 0.1094%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0487%</dd>
+                                    <dd>gnomAD_G_AFR: 0.0344%</dd>
+                                    <dd>gnomAD_G_AMR: 0.1193%</dd>
+                                    <dd>gnomAD_G_EAS: 0.7417%</dd>
+                                    <dd>gnomAD_G_FIN: 0.0286%</dd>
+                                    <dd>gnomAD_G_OTH: 0.1022%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="PKN2" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000065243">PKN2</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.007</b>
+                    <data>(p=5.5E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.514</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.327</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.514 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=PKN2">PKN2</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005344, increased circulating bilirubin level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0005567, decreased circulating total protein level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0000186, decreased circulating HDL cholesterol level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0005344, increased circulating bilirubin level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.176 to zebrafish mutant involving <a href="http://zfin.org/action/quicksearch/query?query=PKN2">PKN2</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - ZP:0000038, pericardium edematous, abnormal</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=PKN2%0DNCKAP1L&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to NCKAP1L</a> and phenotypic similarity 0.474 to <a href="http://www.omim.org/entry/618982">Immunodeficiency 72 with autoinflammation</a> associated with NCKAP1L.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0001903, Anemia - HP:0032184, Increased proportion of memory T cells</dd><dd>HP:0001541, Ascites - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0010972, Anemia of inadequate production - HP:0032184, Increased proportion of memory T cells</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0032184, Increased proportion of memory T cells</dd><dd>HP:0001396, Cholestasis - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0001410, Decreased liver function - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - HP:0032184, Increased proportion of memory T cells</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0032184, Increased proportion of memory T cells</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=PKN2%0DNCKAP1L&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to NCKAP1L</a> and phenotypic similarity 0.712 to mouse mutant of NCKAP1L.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000693, spleen hyperplasia</dd><dd>HP:0001903, Anemia - MP:0002591, decreased mean corpuscular volume</dd><dd>HP:0001541, Ascites - MP:0000693, spleen hyperplasia</dd><dd>HP:0010972, Anemia of inadequate production - MP:0008388, hypochromic microcytic anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0008801, abnormal erythroid progenitor cell morphology</dd><dd>HP:0001396, Cholestasis - MP:0000598, abnormal liver morphology</dd><dd>HP:0001410, Decreased liver function - MP:0001860, liver inflammation</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0001860, liver inflammation</dd><dd>HP:0001399, Hepatic failure - MP:0001860, liver inflammation</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0003141, cardiac fibrosis</dd><dd>HP:0200114, Metabolic alkalosis - MP:0008596, increased circulating interleukin-6 level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0008596, increased circulating interleukin-6 level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0008596, increased circulating interleukin-6 level</dd><dd>HP:0001873, Thrombocytopenia - MP:0000208, decreased hematocrit</dd><dd>HP:0002151, Increased serum lactate - MP:0008596, increased circulating interleukin-6 level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0001860, liver inflammation</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0001860, liver inflammation</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000598, abnormal liver morphology</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0000219, increased neutrophil cell number</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.007</b>
+                                    <data>(p=5.5E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.514</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.327</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>1-88770437-C-A [1/1:0/1:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs35207128">rs35207128</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.327</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000370521.8">PKN2:ENST00000370521.8:c.590C&gt;A:p.(Ala197Glu)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.71012676</dd>
+                                    
+                                    <dd>REVEL: 0.453</dd>
+                                    <dd>MVP: 0.710</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.2342%</dd>
+                                    <dd>TOPMed: 0.0880%</dd>
+                                    <dd>ExAC EAS: 1.2636%</dd>
+                                    <dd>ExAC SAS: 0.0424%</dd>
+                                    <dd>gnomAD_E_EAS: 1.2699%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0009%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0422%</dd>
+                                    <dd>gnomAD_G_EAS: 1.6069%</dd>
+                                    <dd>gnomAD_G_OTH: 0.1022%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="USP7" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000187555">USP7</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.006</b>
+                    <data>(p=5.7E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.269</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.579</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.355 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=500055">Hao-Fountain syndrome due to 16p13.2 microdeletion</a> associated with USP7.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0000135, Hypogonadism</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0000135, Hypogonadism</dd><dd>HP:0001410, Decreased liver function - HP:0000135, Hypogonadism</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0000135, Hypogonadism</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0000135, Hypogonadism</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001508, Failure to thrive</dd></dl><dl><dt>Phenotypic similarity 0.170 to zebrafish mutant involving <a href="http://zfin.org/action/quicksearch/query?query=USP7">USP7</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - ZP:0000038, pericardium edematous, abnormal</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.538 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=USP7%0DFBXO38&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to FBXO38</a> and phenotypic similarity 0.130 to <a href="http://www.omim.org/entry/615575">Neuronopathy, distal hereditary motor, type IID</a> associated with FBXO38.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0003431, Decreased motor nerve conduction velocity</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.538 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=USP7%0DFBXO38&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to FBXO38</a> and phenotypic similarity 0.603 to mouse mutant of FBXO38.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000601, small liver</dd><dd>HP:0001903, Anemia - MP:0010067, increased red blood cell distribution width</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0010067, increased red blood cell distribution width</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0002606, increased basophil cell number</dd><dd>HP:0001396, Cholestasis - MP:0000601, small liver</dd><dd>HP:0001410, Decreased liver function - MP:0000601, small liver</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000601, small liver</dd><dd>HP:0001399, Hepatic failure - MP:0000601, small liver</dd><dd>HP:0000938, Osteopenia - MP:0000063, decreased bone mineral density</dd><dd>HP:0001642, Pulmonic stenosis - MP:0002626, increased heart rate</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005343, increased circulating aspartate transaminase level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002941, increased circulating alanine transaminase level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0002941, increased circulating alanine transaminase level</dd><dd>HP:0001873, Thrombocytopenia - MP:0002599, increased mean platelet volume</dd><dd>HP:0002151, Increased serum lactate - MP:0005343, increased circulating aspartate transaminase level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000601, small liver</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000601, small liver</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000601, small liver</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0005013, increased lymphocyte cell number</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dl>
+<dt>Known diseases - observed variants incompatible with mode of inheritance:</dt>
+<dd><a href="http://www.omim.org/entry/616863">OMIM:616863</a> Hao-Fountain syndrome - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=500055">ORPHA:500055</a> Hao-Fountain syndrome due to 16p13.2 microdeletion (CNV)</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.006</b>
+                                    <data>(p=5.7E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.269</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.579</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SPLICE_REGION_VARIANT</span>
+                            <b>DEL</b>
+                            <b>16-8894647-GA-G [1/1:0/1:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs373482138">rs373482138</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP6]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    <span class="label label-success">BENIGN</span>
+                                
+                                
+                                
+                                
+                                
+                                
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=2098649%5Balleleid%5D">(criteria provided, single submitter)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.579</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000344836.9">USP7:ENST00000344836.9:c.3112-8del:p.?</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.3435%</dd>
+                                    <dd>TOPMed: 0.3435%</dd>
+                                    <dd>ExAC AFR: 0.0300%</dd>
+                                    <dd>ExAC AMR: 0.0087%</dd>
+                                    <dd>ExAC EAS: 0.8429%</dd>
+                                    <dd>ExAC NFE: 0.0015%</dd>
+                                    <dd>ExAC SAS: 0.0485%</dd>
+                                    <dd>gnomAD_E_AFR: 0.0395%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0061%</dd>
+                                    <dd>gnomAD_E_EAS: 0.8011%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0027%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0185%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0394%</dd>
+                                    <dd>gnomAD_G_AFR: 0.0577%</dd>
+                                    <dd>gnomAD_G_EAS: 1.1125%</dd>
+                                    <dd>gnomAD_G_OTH: 0.1035%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="DNAH1" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000114841">DNAH1</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.006</b>
+                    <data>(p=5.7E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.341</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.497</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.341 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=244">Primary ciliary dyskinesia</a> associated with DNAH1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001746, Asplenia</dd><dd>HP:0001903, Anemia - HP:0001746, Asplenia</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001746, Asplenia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001746, Asplenia</dd><dd>HP:0001396, Cholestasis - HP:0001746, Asplenia</dd><dd>HP:0001410, Decreased liver function - HP:0001746, Asplenia</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0001746, Asplenia</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001627, Abnormal heart morphology</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - HP:0001746, Asplenia</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001746, Asplenia</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001669, Transposition of the great arteries</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.09 (p-value: 0.958770)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/617576">OMIM:617576</a> Spermatogenic failure 18 - autosomal recessive</dd>
+<dd><a href="http://www.omim.org/entry/617577">OMIM:617577</a> Ciliary dyskinesia, primary, 37 - autosomal recessive</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=244">ORPHA:244</a> Primary ciliary dyskinesia - autosomal recessive</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.006</b>
+                                    <data>(p=5.7E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.341</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.497</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.341 to ORPHA:244 Primary ciliary dyskinesia</dt>
+                                
+                                    <dt>Phenotypic similarity 0.267 to OMIM:617577 Ciliary dyskinesia, primary, 37</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>3-52392945-A-G [0/1:0/0:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs375477856">rs375477856</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=965669%5Balleleid%5D">(criteria provided, multiple submitters, no conflicts)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.530</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000420323.7">DNAH1:ENST00000420323.7:c.10394A&gt;G:p.(Asn3465Ser)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.53119737</dd>
+                                    
+                                    <dd>REVEL: 0.272</dd>
+                                    <dd>MVP: 0.531</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>ESP EA: 0.0119%</dd>
+                                    <dd>ESP All: 0.0079%</dd>
+                                    <dd>ExAC NFE: 0.0105%</dd>
+                                    <dd>ExAC SAS: 0.0061%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0081%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0182%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0065%</dd>
+                                    <dd>gnomAD_G_AFR: 0.0115%</dd>
+                                    <dd>gnomAD_G_NFE: 0.0134%</dd>
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>3-52399696-T-C [0/1:0/1:0/0]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.464</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000420323.7">DNAH1:ENST00000420323.7:c.12593T&gt;C:p.(Ile4198Thr)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.46435556</dd>
+                                    
+                                    <dd>REVEL: 0.339</dd>
+                                    <dd>MVP: 0.464</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="FAM47A" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000185448">FAM47A</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.004</b>
+                    <data>(p=6.1E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.000</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.850</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>No phenotype or PPI evidence</dt></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>X_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.004</b>
+                                    <data>(p=6.1E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.000</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.850</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">INFRAME_DELETION</span>
+                            <b>DEL</b>
+                            <b>X-34130760-CCGAGCGGAGACTGGACGTCCGACGAGTCTTGGGAGGCTG-C [1/1:0/0:0/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting, PM4]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.850</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000346193.5">FAM47A:ENST00000346193.5:c.1480_1518del:p.(Gln494_Ser506del)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="SPANXB1" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000227234">SPANXB1</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.004</b>
+                    <data>(p=6.1E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.000</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.850</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>No phenotype or PPI evidence</dt></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>X_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.004</b>
+                                    <data>(p=6.1E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.000</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.850</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">DISRUPTIVE_INFRAME_DELETION</span>
+                            <b>DEL</b>
+                            <b>X-141002745-TCCAACGAGG-T [0/1:0/0:./.]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs1259923760">rs1259923760</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.850</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000449283.2">SPANXB1:ENST00000449283.2:c.66_74del:p.(Glu26_Asn28del)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>X_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.004</b>
+                                    <data>(p=6.1E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.000</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.850</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">DISRUPTIVE_INFRAME_DELETION</span>
+                            <b>DEL</b>
+                            <b>X-141002745-TCCAACGAGG-T [0/1:0/0:./.]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs1259923760">rs1259923760</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.850</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000449283.2">SPANXB1:ENST00000449283.2:c.66_74del:p.(Glu26_Asn28del)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="ARHGAP4" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000089820">ARHGAP4</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.004</b>
+                    <data>(p=6.2E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.275</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ARHGAP4%0DSLC12A1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SLC12A1</a> and phenotypic similarity 0.629 to <a href="http://www.omim.org/entry/601678">Bartter syndrome, type 1</a> associated with SLC12A1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0000843, Hyperparathyroidism</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - HP:0001944, Dehydration</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0000938, Osteopenia</dd><dd>HP:0001396, Cholestasis - HP:0000841, Hyperactive renin-angiotensin system</dd><dd>HP:0001410, Decreased liver function - HP:0000843, Hyperparathyroidism</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0000843, Hyperparathyroidism</dd><dd>HP:0000938, Osteopenia - HP:0000938, Osteopenia</dd><dd>HP:0001642, Pulmonic stenosis - HP:0002632, Low-to-normal blood pressure</dd><dd>HP:0200114, Metabolic alkalosis - HP:0001960, Hypokalemic metabolic alkalosis</dd><dd>HP:0003073, Hypoalbuminemia - HP:0000848, Increased circulating renin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003566, Increased serum prostaglandin E2</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0000848, Increased circulating renin level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0000848, Increased circulating renin level</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001508, Failure to thrive</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ARHGAP4%0DSLC12A1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SLC12A1</a> and phenotypic similarity 0.550 to mouse mutant of SLC12A1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia - MP:0002608, increased hematocrit</dd><dd>HP:0001541, Ascites - MP:0001784, abnormal fluid regulation</dd><dd>HP:0010972, Anemia of inadequate production - MP:0002608, increased hematocrit</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function - MP:0005582, increased renin activity</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0005582, increased renin activity</dd><dd>HP:0001399, Hepatic failure - MP:0005582, increased renin activity</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0012551, metabolic acidosis</dd><dd>HP:0003073, Hypoalbuminemia - MP:0005568, increased circulating total protein level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0005568, increased circulating total protein level</dd><dd>HP:0001873, Thrombocytopenia - MP:0002608, increased hematocrit</dd><dd>HP:0002151, Increased serum lactate - MP:0012551, metabolic acidosis</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0005582, increased renin activity</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0005582, increased renin activity</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0005560, decreased circulating glucose level</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0002608, increased hematocrit</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001732, postnatal growth retardation</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>X_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.004</b>
+                                    <data>(p=6.2E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.275</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>X-153920694-C-T [0/1:0/0:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs147143769">rs147143769</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4_Moderate]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.275</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000350060.10">ARHGAP4:ENST00000350060.10:c.613G&gt;A:p.(Ala205Thr)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.27715346</dd>
+                                    
+                                    <dd>REVEL: 0.025</dd>
+                                    <dd>MVP: 0.277</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>TOPMed: 0.0068%</dd>
+                                    <dd>ESP EA: 0.0446%</dd>
+                                    <dd>ESP All: 0.0284%</dd>
+                                    <dd>ExAC NFE: 0.0065%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0064%</dd>
+                                    <dd>gnomAD_G_AFR: 0.0167%</dd>
+                                    <dd>gnomAD_G_NFE: 0.0096%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+                <div class="row">
+                    <div class="col-sm-12">
+                        <b>Other passed variants:</b>
+                    </div>
+                </div>
+                
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                        <b>SNV</b>
+                        <b>X-153921709-G-A [0/1:0/0:0/1]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs377321582">rs377321582</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.088</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000350060.10">ARHGAP4:ENST00000350060.10:c.168C&gt;T:p.(=)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            
+                            <dd>1000Genomes: 0.0833%</dd>
+                            <dd>TOPMed: 0.0249%</dd>
+                            <dd>UK10K: 0.0152%</dd>
+                            <dd>ESP AA: 0.0262%</dd>
+                            <dd>ESP All: 0.0095%</dd>
+                            <dd>ExAC AFR: 0.1472%</dd>
+                            <dd>ExAC EAS: 0.2674%</dd>
+                            <dd>ExAC NFE: 0.0162%</dd>
+                            <dd>ExAC OTH: 0.6494%</dd>
+                            <dd>ExAC SAS: 0.0146%</dd>
+                            <dd>gnomAD_E_AFR: 0.0790%</dd>
+                            <dd>gnomAD_E_AMR: 0.0119%</dd>
+                            <dd>gnomAD_E_EAS: 0.2041%</dd>
+                            <dd>gnomAD_E_NFE: 0.0077%</dd>
+                            <dd>gnomAD_E_OTH: 0.2518%</dd>
+                            <dd>gnomAD_E_SAS: 0.0231%</dd>
+                            <dd>gnomAD_G_AFR: 0.0502%</dd>
+                            <dd>gnomAD_G_EAS: 0.1921%</dd>
+                            <dd>gnomAD_G_OTH: 0.1391%</dd>
+                        </dl>
+                    </div>
+                </div>
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="PAPPA2" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000116183">PAPPA2</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.003</b>
+                    <data>(p=6.4E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.503</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.251</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.503 to <a href="http://www.omim.org/entry/619489">Short stature, Dauber-Argente type</a> associated with PAPPA2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0008283, Fasting hyperinsulinemia</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0004349, Reduced bone mineral density</dd><dd>HP:0001396, Cholestasis - HP:0008283, Fasting hyperinsulinemia</dd><dd>HP:0001410, Decreased liver function - HP:0008283, Fasting hyperinsulinemia</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0008283, Fasting hyperinsulinemia</dd><dd>HP:0000938, Osteopenia - HP:0000938, Osteopenia</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - HP:0008283, Fasting hyperinsulinemia</dd><dd>HP:0003073, Hypoalbuminemia - HP:0034184, Increased insulin like growth factor binding protein acid labile subunit concentration</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0034184, Increased insulin like growth factor binding protein acid labile subunit concentration</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0008283, Fasting hyperinsulinemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0008283, Fasting hyperinsulinemia</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.497 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=PAPPA2">PAPPA2</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0002981, increased liver weight</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - MP:0002981, increased liver weight</dd><dd>HP:0010972, Anemia of inadequate production - MP:0004952, increased spleen weight</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0002981, increased liver weight</dd><dd>HP:0001410, Decreased liver function - MP:0002981, increased liver weight</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0002981, increased liver weight</dd><dd>HP:0001399, Hepatic failure - MP:0002981, increased liver weight</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0002833, increased heart weight</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0002981, increased liver weight</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0002981, increased liver weight</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0002176, increased brain weight</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0002981, increased liver weight</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001732, postnatal growth retardation</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=PAPPA2%0DCTSG&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to CTSG</a> and phenotypic similarity 0.622 to mouse mutant of CTSG.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000599, enlarged liver</dd><dd>HP:0001903, Anemia - MP:0001577, anemia</dd><dd>HP:0001541, Ascites - MP:0000599, enlarged liver</dd><dd>HP:0010972, Anemia of inadequate production - MP:0001601, abnormal myelopoiesis</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0000218, increased leukocyte cell number</dd><dd>HP:0001396, Cholestasis - MP:0000599, enlarged liver</dd><dd>HP:0001410, Decreased liver function - MP:0000599, enlarged liver</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000599, enlarged liver</dd><dd>HP:0001399, Hepatic failure - MP:0000599, enlarged liver</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - MP:0003179, thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000599, enlarged liver</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000599, enlarged liver</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000599, enlarged liver</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0000218, increased leukocyte cell number</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/619489">OMIM:619489</a> Short stature, Dauber-Argente type - autosomal recessive</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.003</b>
+                                    <data>(p=6.4E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.503</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.251</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.503 to OMIM:619489 Short stature, Dauber-Argente type</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>1-176594926-G-A [0/1:0/1:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs374840800">rs374840800</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4_Moderate]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=2194332%5Balleleid%5D">(criteria provided, single submitter)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.402</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000367662.5">PAPPA2:ENST00000367662.5:c.1322G&gt;A:p.(Ser441Asn)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.4081723</dd>
+                                    
+                                    <dd>REVEL: 0.100</dd>
+                                    <dd>MVP: 0.408</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>TOPMed: 0.0072%</dd>
+                                    <dd>ExAC EAS: 0.0348%</dd>
+                                    <dd>ExAC SAS: 0.0061%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0290%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0183%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0032%</dd>
+                                    <dd>gnomAD_G_OTH: 0.1018%</dd>
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                            <b>SNV</b>
+                            <b>1-176702685-T-G [0/1:0/0:0/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.100</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000367662.5">PAPPA2:ENST00000367662.5:c.3315T&gt;G:p.(=)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="PRAMEF15" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000204501">PRAMEF15</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.003</b>
+                    <data>(p=6.6E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.401</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.346</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.401 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=PRAMEF15">PRAMEF15</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000691, enlarged spleen</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - MP:0000691, enlarged spleen</dd><dd>HP:0010972, Anemia of inadequate production - MP:0000689, abnormal spleen morphology</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0001944, abnormal pancreas morphology</dd><dd>HP:0001410, Decreased liver function - MP:0001944, abnormal pancreas morphology</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0001944, abnormal pancreas morphology</dd><dd>HP:0001399, Hepatic failure - MP:0001944, abnormal pancreas morphology</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0000266, abnormal heart morphology</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0001944, abnormal pancreas morphology</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0001944, abnormal pancreas morphology</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0001944, abnormal pancreas morphology</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.003</b>
+                                    <data>(p=6.6E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.401</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.346</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>1-13322125-T-G [0/1:0/0:./.]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs1272016578">rs1272016578</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[PM2_Supporting, BP4_Moderate]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.346</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000376152.2">PRAMEF15:ENST00000376152.2:c.1298T&gt;G:p.(Phe433Cys)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.34563237</dd>
+                                    
+                                    <dd>REVEL: 0.035</dd>
+                                    <dd>MVP: 0.346</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+                <div class="row">
+                    <div class="col-sm-12">
+                        <b>Other passed variants:</b>
+                    </div>
+                </div>
+                
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">MISSENSE_VARIANT</span>
+                        <b>SNV</b>
+                        <b>1-13322094-G-A [0/1:0/0:./.]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs1200491508">rs1200491508</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.040</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000376152.2">PRAMEF15:ENST00000376152.2:c.1267G&gt;A:p.(Gly423Ser)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            <dd>Best Score: 0.04010828</dd>
+                            
+                            <dd>REVEL: 0.010</dd>
+                            <dd>MVP: 0.040</dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            <dd>No frequency data</dd>
+                            
+                        </dl>
+                    </div>
+                </div>
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="KRT84" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000161849">KRT84</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.003</b>
+                    <data>(p=6.6E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.000</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.798</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>No phenotype or PPI evidence</dt></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.003</b>
+                                    <data>(p=6.6E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.000</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.798</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>12-52381507-A-G [1/1:0/1:0/1]</b>
+                            
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.798</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000257951.3">KRT84:ENST00000257951.3:c.931T&gt;C:p.(Ser311Pro)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.79798794</dd>
+                                    
+                                    <dd>REVEL: 0.455</dd>
+                                    <dd>MVP: 0.798</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="GOLGA6A" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000159289">GOLGA6A</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.003</b>
+                    <data>(p=6.6E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.000</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.797</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>No phenotype or PPI evidence</dt></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.003</b>
+                                    <data>(p=6.6E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.000</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.797</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SPLICE_REGION_VARIANT</span>
+                            <b>SNV</b>
+                            <b>15-74071548-G-A [0/1:./.:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs1219693041">rs1219693041</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.797</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000290438.3">GOLGA6A:ENST00000290438.3:c.1696+6C&gt;T:p.?</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0156%</dd>
+                                    <dd>TOPMed: 0.0156%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0157%</dd>
+                                    <dd>gnomAD_G_AFR: 0.0241%</dd>
+                                    <dd>gnomAD_G_NFE: 0.0073%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="MRPL45" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000278845">MRPL45</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.002</b>
+                    <data>(p=6.8E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.506</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.207</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Proximity score 0.506 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=MRPL45%0DSMC5&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SMC5</a> and phenotypic similarity 0.561 to <a href="http://www.omim.org/entry/620185">Atelis syndrome 2</a> associated with SMC5.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0000771, Gynecomastia</dd><dd>HP:0001903, Anemia - HP:0001903, Anemia</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001903, Anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001903, Anemia</dd><dd>HP:0001396, Cholestasis - HP:0002925, Elevated circulating thyroid-stimulating hormone concentration</dd><dd>HP:0001410, Decreased liver function - HP:0002925, Elevated circulating thyroid-stimulating hormone concentration</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0002925, Elevated circulating thyroid-stimulating hormone concentration</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001642, Pulmonic stenosis</dd><dd>HP:0200114, Metabolic alkalosis - HP:0000842, Hyperinsulinemia</dd><dd>HP:0003073, Hypoalbuminemia - HP:0000842, Hyperinsulinemia</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0000842, Hyperinsulinemia</dd><dd>HP:0001873, Thrombocytopenia - HP:0001873, Thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate - HP:0000842, Hyperinsulinemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0000842, Hyperinsulinemia</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001903, Anemia</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.506 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=MRPL45%0DSMC5&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SMC5</a> and phenotypic similarity 0.602 to mouse mutant of SMC5.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0005011, increased eosinophil cell number</dd><dd>HP:0001903, Anemia - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0005011, increased eosinophil cell number</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0005016, decreased lymphocyte cell number</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005344, increased circulating bilirubin level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0000186, decreased circulating HDL cholesterol level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0000186, decreased circulating HDL cholesterol level</dd><dd>HP:0001873, Thrombocytopenia - MP:0003179, thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate - MP:0005344, increased circulating bilirubin level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0005560, decreased circulating glucose level</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0000219, increased neutrophil cell number</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.002</b>
+                                    <data>(p=6.8E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.506</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.207</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>17-38297226-T-G [1/1:./.:./.]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs9890011">rs9890011</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4_Moderate]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.207</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000613675.5">MRPL45:ENST00000613675.5:c.43T&gt;G:p.(Phe15Val)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.25778696</dd>
+                                    
+                                    <dd>REVEL: 0.102</dd>
+                                    <dd>MVP: 0.258</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.4685%</dd>
+                                    <dd>TOPMed: 0.2803%</dd>
+                                    <dd>gnomAD_E_AFR: 0.8131%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0687%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0036%</dd>
+                                    <dd>gnomAD_E_OTH: 0.1097%</dd>
+                                    <dd>gnomAD_G_AFR: 0.8953%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="EXOC6B" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000144036">EXOC6B</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.002</b>
+                    <data>(p=6.8E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.505</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.207</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.234 to <a href="http://www.omim.org/entry/618395">Spondyloepimetaphyseal dysplasia with joint laxity, type 3</a> associated with EXOC6B.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001216, Delayed ossification of carpal bones</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia - HP:0001216, Delayed ossification of carpal bones</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001513, Obesity</dd></dl><dl><dt>Phenotypic similarity 0.152 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=EXOC6B">EXOC6B</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0005560, decreased circulating glucose level</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.505 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=EXOC6B%0DRABL2A&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to RABL2A</a> and phenotypic similarity 0.620 to mouse mutant of RABL2A.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0002981, increased liver weight</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - MP:0002981, increased liver weight</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0010124, decreased bone mineral content</dd><dd>HP:0001396, Cholestasis - MP:0002981, increased liver weight</dd><dd>HP:0001410, Decreased liver function - MP:0002981, increased liver weight</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0002981, increased liver weight</dd><dd>HP:0001399, Hepatic failure - MP:0002981, increased liver weight</dd><dd>HP:0000938, Osteopenia - MP:0000063, decreased bone mineral density</dd><dd>HP:0001642, Pulmonic stenosis - MP:0006203, eye hemorrhage</dd><dd>HP:0200114, Metabolic alkalosis - MP:0002079, increased circulating insulin level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002079, increased circulating insulin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0000186, decreased circulating HDL cholesterol level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0002079, increased circulating insulin level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0002981, increased liver weight</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0002981, increased liver weight</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0002981, increased liver weight</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/618395">OMIM:618395</a> Spondyloepimetaphyseal dysplasia with joint laxity, type 3 - autosomal recessive</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.002</b>
+                                    <data>(p=6.8E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.505</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.207</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.234 to OMIM:618395 Spondyloepimetaphyseal dysplasia with joint laxity, type 3</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SPLICE_REGION_VARIANT</span>
+                            <b>SNV</b>
+                            <b>2-72492312-G-C [1/1:0/1:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs181182127">rs181182127</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP6]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    <span class="label label-success">BENIGN</span>
+                                
+                                
+                                
+                                
+                                
+                                
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=730161%5Balleleid%5D">(criteria provided, single submitter)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.207</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000272427.11">EXOC6B:ENST00000272427.11:c.1665+6C&gt;G:p.?</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.3123%</dd>
+                                    <dd>TOPMed: 0.3123%</dd>
+                                    <dd>ExAC EAS: 1.8686%</dd>
+                                    <dd>ExAC OTH: 0.1121%</dd>
+                                    <dd>ExAC SAS: 0.0245%</dd>
+                                    <dd>gnomAD_E_EAS: 1.6943%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0367%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0325%</dd>
+                                    <dd>gnomAD_G_EAS: 1.7348%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="KCNN4" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000104783">KCNN4</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.002</b>
+                    <data>(p=7.1E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.595</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.077</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.657 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=3202">Dehydrated hereditary stomatocytosis</a> associated with KCNN4.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001744, Splenomegaly</dd><dd>HP:0001903, Anemia - HP:0001878, Hemolytic anemia</dd><dd>HP:0001541, Ascites - HP:0000969, Edema</dd><dd>HP:0010972, Anemia of inadequate production - HP:0010972, Anemia of inadequate production</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0010972, Anemia of inadequate production</dd><dd>HP:0001396, Cholestasis - HP:0001046, Intermittent jaundice</dd><dd>HP:0001410, Decreased liver function - HP:0001081, Cholelithiasis</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0025435, Increased circulating lactate dehydrogenase concentration</dd><dd>HP:0001399, Hepatic failure - HP:0001081, Cholelithiasis</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0030950, Pulmonary venous hypertension</dd><dd>HP:0200114, Metabolic alkalosis - HP:0000969, Edema</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003281, Increased circulating ferritin concentration</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003281, Increased circulating ferritin concentration</dd><dd>HP:0001873, Thrombocytopenia - HP:0001901, Polycythemia</dd><dd>HP:0002151, Increased serum lactate - HP:0003573, Increased total bilirubin</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0025435, Increased circulating lactate dehydrogenase concentration</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0025435, Increased circulating lactate dehydrogenase concentration</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0030242, Portal vein thrombosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0010972, Anemia of inadequate production</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.519 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=KCNN4">KCNN4</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000691, enlarged spleen</dd><dd>HP:0001903, Anemia - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0001541, Ascites - MP:0000691, enlarged spleen</dd><dd>HP:0010972, Anemia of inadequate production - MP:0002874, decreased hemoglobin content</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0000598, abnormal liver morphology</dd><dd>HP:0001410, Decreased liver function - MP:0000598, abnormal liver morphology</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000598, abnormal liver morphology</dd><dd>HP:0001399, Hepatic failure - MP:0000598, abnormal liver morphology</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0000266, abnormal heart morphology</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002874, decreased hemoglobin content</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0002874, decreased hemoglobin content</dd><dd>HP:0001873, Thrombocytopenia - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000598, abnormal liver morphology</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000598, abnormal liver morphology</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000601, small liver</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0010067, increased red blood cell distribution width</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.505 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=KCNN4%0DIKZF1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to IKZF1</a> and phenotypic similarity 0.705 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=36426">Stevens-Johnson syndrome</a> associated with IKZF1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0006554, Acute hepatic failure</dd><dd>HP:0001903, Anemia - HP:0001903, Anemia</dd><dd>HP:0001541, Ascites - HP:0003781, Excessive salivation</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001903, Anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001874, Abnormality of neutrophils</dd><dd>HP:0001396, Cholestasis - HP:0006554, Acute hepatic failure</dd><dd>HP:0001410, Decreased liver function - HP:0006554, Acute hepatic failure</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0001399, Hepatic failure - HP:0006554, Acute hepatic failure</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001658, Myocardial infarction</dd><dd>HP:0200114, Metabolic alkalosis - HP:0001960, Hypokalemic metabolic alkalosis</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - HP:0001873, Thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate - HP:0001960, Hypokalemic metabolic alkalosis</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0006554, Acute hepatic failure</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001874, Abnormality of neutrophils</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001824, Weight loss</dd></dl><dl><dt>Proximity score 0.505 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=KCNN4%0DIKZF1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to IKZF1</a> and phenotypic similarity 0.594 to mouse mutant of IKZF1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000600, liver hypoplasia</dd><dd>HP:0001903, Anemia - MP:0001577, anemia</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0001601, abnormal myelopoiesis</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0011176, abnormal erythroblast morphology</dd><dd>HP:0001396, Cholestasis - MP:0000600, liver hypoplasia</dd><dd>HP:0001410, Decreased liver function - MP:0000600, liver hypoplasia</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000600, liver hypoplasia</dd><dd>HP:0001399, Hepatic failure - MP:0000600, liver hypoplasia</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002874, decreased hemoglobin content</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0002874, decreased hemoglobin content</dd><dd>HP:0001873, Thrombocytopenia - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000600, liver hypoplasia</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000600, liver hypoplasia</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000600, liver hypoplasia</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0005425, increased macrophage cell number</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.505 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=KCNN4%0DIKZF1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to IKZF1</a> and phenotypic similarity 0.337 to fish mutant of IKZF1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - ZP:0004774, thymus lacks parts or has fewer parts of type lymphocyte, abnormal</dd><dd>HP:0001903, Anemia - ZP:0004774, thymus lacks parts or has fewer parts of type lymphocyte, abnormal</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - ZP:0010760, lymphoid lineage cell migration into thymus involved in thymus epithelium morphogenesis disrupted, abnormal</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - ZP:0004774, thymus lacks parts or has fewer parts of type lymphocyte, abnormal</dd><dd>HP:0001396, Cholestasis - ZP:0004774, thymus lacks parts or has fewer parts of type lymphocyte, abnormal</dd><dd>HP:0001410, Decreased liver function - ZP:0004774, thymus lacks parts or has fewer parts of type lymphocyte, abnormal</dd><dd>HP:0002910, Elevated hepatic transaminase - ZP:0004774, thymus lacks parts or has fewer parts of type lymphocyte, abnormal</dd><dd>HP:0001399, Hepatic failure - ZP:0004774, thymus lacks parts or has fewer parts of type lymphocyte, abnormal</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - ZP:0004774, thymus lacks parts or has fewer parts of type lymphocyte, abnormal</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - ZP:0004774, thymus lacks parts or has fewer parts of type lymphocyte, abnormal</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - ZP:0004774, thymus lacks parts or has fewer parts of type lymphocyte, abnormal</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - ZP:0010760, lymphoid lineage cell migration into thymus involved in thymus epithelium morphogenesis disrupted, abnormal</dd><dd>HP:0004333, Bone-marrow foam cells - ZP:0004774, thymus lacks parts or has fewer parts of type lymphocyte, abnormal</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 1.20 (p-value: 0.000010)</dt></dl><dl>
+<dt>Known diseases:</dt>
+<dd><a href="http://www.omim.org/entry/616689">OMIM:616689</a> Dehydrated hereditary stomatocytosis 2 - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=3202">ORPHA:3202</a> Dehydrated hereditary stomatocytosis - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=586">ORPHA:586</a> Cystic fibrosis (unconfirmed)</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.002</b>
+                                    <data>(p=7.1E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.595</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.077</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            
+                            <dl class="list-group">
+                                <!--                            th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}">-->
+                                <dt>
+                                    Phenotype matches to diseases consistent with this MOI:
+                                </dt>
+                                <!--                            <dt th:each="diseaseModel: ${geneScore.getCompatibleDiseaseMatches()}"-->
+                                <!--                                th:text="Phenotypic similarity ${diseaseModel.getScore()} to ${diseaseModel.getModel().getDiseaseName()}">-->
+                                <!--                                Phenotypic similarity 0.95 to APERT SYNDROME-->
+                                <!--                            </dt>-->
+                                
+                                    <dt>Phenotypic similarity 0.595 to ORPHA:586 Cystic fibrosis</dt>
+                                
+                            </dl>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                            <b>SNV</b>
+                            <b>19-43780712-C-T [0/1:0/1:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs200169896">rs200169896</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.081</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000648319.1">KCNN4:ENST00000648319.1:c.150G&gt;A:p.(=)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0781%</dd>
+                                    <dd>TOPMed: 0.0781%</dd>
+                                    <dd>ESP AA: 0.0227%</dd>
+                                    <dd>ESP All: 0.0077%</dd>
+                                    <dd>ExAC AMR: 0.0086%</dd>
+                                    <dd>ExAC EAS: 0.5666%</dd>
+                                    <dd>ExAC OTH: 0.2203%</dd>
+                                    <dd>ExAC SAS: 0.0061%</dd>
+                                    <dd>gnomAD_E_AFR: 0.0065%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0119%</dd>
+                                    <dd>gnomAD_E_EAS: 0.6320%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0009%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0731%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0162%</dd>
+                                    <dd>gnomAD_G_AFR: 0.0115%</dd>
+                                    <dd>gnomAD_G_EAS: 0.8642%</dd>
+                                    <dd>gnomAD_G_NFE: 0.0067%</dd>
+                                    <dd>gnomAD_G_OTH: 0.1025%</dd>
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                            <b>SNV</b>
+                            <b>19-43774371-G-A [0/1:0/0:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs551228061">rs551228061</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP6]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    <span class="label label-success">BENIGN</span>
+                                
+                                
+                                
+                                
+                                
+                                
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=728249%5Balleleid%5D">(criteria provided, single submitter)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.072</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000648319.1">KCNN4:ENST00000648319.1:c.504C&gt;T:p.(=)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0468%</dd>
+                                    <dd>TOPMed: 0.0366%</dd>
+                                    <dd>ExAC AFR: 0.0169%</dd>
+                                    <dd>ExAC EAS: 0.7015%</dd>
+                                    <dd>gnomAD_E_AFR: 0.0153%</dd>
+                                    <dd>gnomAD_E_EAS: 0.6373%</dd>
+                                    <dd>gnomAD_G_EAS: 1.1111%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="MUC3A" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000169894">MUC3A</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.001</b>
+                    <data>(p=7.3E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.000</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.725</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>No phenotype or PPI evidence</dt></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.001</b>
+                                    <data>(p=7.3E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.000</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.725</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">DISRUPTIVE_INFRAME_DELETION</span>
+                            <b>DEL</b>
+                            <b>7-100957124-TAGG-T [0/1:./.:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs1422404475">rs1422404475</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.850</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000379458.9">MUC3A:ENST00000379458.9:c.5346_5348del:p.(Gly1783del)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>7-100953812-T-C [0/1:./.:./.]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs1385924525">rs1385924525</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.600</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000379458.9">MUC3A:ENST00000379458.9:c.2033T&gt;C:p.(Val678Ala)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.000</b>
+                                    <data>(p=8.5E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.000</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.600</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>7-100953755-C-G [0/1:0/0:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs879161245">rs879161245</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.600</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000379458.9">MUC3A:ENST00000379458.9:c.1976C&gt;G:p.(Ser659Cys)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+                <div class="row">
+                    <div class="col-sm-12">
+                        <b>Other passed variants:</b>
+                    </div>
+                </div>
+                
+                
+                
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">MISSENSE_VARIANT</span>
+                        <b>SNV</b>
+                        <b>7-100953697-T-C [0/1:./.:0/1]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs1298273392">rs1298273392</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.600</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000379458.9">MUC3A:ENST00000379458.9:c.1918T&gt;C:p.(Ser640Pro)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            <dd>No frequency data</dd>
+                            
+                        </dl>
+                    </div>
+                </div>
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">MISSENSE_VARIANT</span>
+                        <b>SNV</b>
+                        <b>7-100953728-C-T [0/1:0/0:0/1]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs982221309">rs982221309</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.600</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000379458.9">MUC3A:ENST00000379458.9:c.1949C&gt;T:p.(Thr650Met)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            <dd>No frequency data</dd>
+                            
+                        </dl>
+                    </div>
+                </div>
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">MISSENSE_VARIANT</span>
+                        <b>SNV</b>
+                        <b>7-100953770-C-G [0/1:0/0:./.]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs1289165986">rs1289165986</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.600</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000379458.9">MUC3A:ENST00000379458.9:c.1991C&gt;G:p.(Thr664Ser)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            <dd>No frequency data</dd>
+                            
+                        </dl>
+                    </div>
+                </div>
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">MISSENSE_VARIANT</span>
+                        <b>SNV</b>
+                        <b>7-100953776-T-A [0/1:0/0:./.]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs1307985701">rs1307985701</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.600</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000379458.9">MUC3A:ENST00000379458.9:c.1997T&gt;A:p.(Met666Lys)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            <dd>No frequency data</dd>
+                            
+                        </dl>
+                    </div>
+                </div>
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">MISSENSE_VARIANT</span>
+                        <b>SNV</b>
+                        <b>7-100953779-C-T [0/1:0/0:0/1]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs1375512213">rs1375512213</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.600</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000379458.9">MUC3A:ENST00000379458.9:c.2000C&gt;T:p.(Pro667Leu)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            <dd>No frequency data</dd>
+                            
+                        </dl>
+                    </div>
+                </div>
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">MISSENSE_VARIANT</span>
+                        <b>SNV</b>
+                        <b>7-100955779-C-A [1/1:./.:./.]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs1313584776">rs1313584776</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.600</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000379458.9">MUC3A:ENST00000379458.9:c.4000C&gt;A:p.(Pro1334Thr)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            <dd>No frequency data</dd>
+                            
+                        </dl>
+                    </div>
+                </div>
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">MISSENSE_VARIANT</span>
+                        <b>SNV</b>
+                        <b>7-100955888-C-T [0/1:0/1:0/0]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs1443550411">rs1443550411</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.600</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000379458.9">MUC3A:ENST00000379458.9:c.4109C&gt;T:p.(Thr1370Ile)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            <dd>No frequency data</dd>
+                            
+                        </dl>
+                    </div>
+                </div>
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">MISSENSE_VARIANT</span>
+                        <b>SNV</b>
+                        <b>7-100955950-A-G [0/1:0/1:0/0]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs1380133592">rs1380133592</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.600</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000379458.9">MUC3A:ENST00000379458.9:c.4171A&gt;G:p.(Ile1391Val)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            <dd>No frequency data</dd>
+                            
+                        </dl>
+                    </div>
+                </div>
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">MISSENSE_VARIANT</span>
+                        <b>SNV</b>
+                        <b>7-100956008-C-G [0/1:0/1:./.]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs1314196169">rs1314196169</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.600</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000379458.9">MUC3A:ENST00000379458.9:c.4229C&gt;G:p.(Thr1410Ser)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            <dd>No frequency data</dd>
+                            
+                        </dl>
+                    </div>
+                </div>
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">MISSENSE_VARIANT</span>
+                        <b>SNV</b>
+                        <b>7-100956269-C-T [0/1:0/0:0/0]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs1435832477">rs1435832477</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.600</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000379458.9">MUC3A:ENST00000379458.9:c.4490C&gt;T:p.(Pro1497Leu)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            <dd>No frequency data</dd>
+                            
+                        </dl>
+                    </div>
+                </div>
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                        <b>SNV</b>
+                        <b>7-100953741-C-T [0/1:0/0:0/1]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs1181790485">rs1181790485</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.100</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000379458.9">MUC3A:ENST00000379458.9:c.1962C&gt;T:p.(=)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            <dd>No frequency data</dd>
+                            
+                        </dl>
+                    </div>
+                </div>
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                        <b>SNV</b>
+                        <b>7-100953789-T-C [0/1:0/0:0/1]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs1457246080">rs1457246080</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.100</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000379458.9">MUC3A:ENST00000379458.9:c.2010T&gt;C:p.(=)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            <dd>No frequency data</dd>
+                            
+                        </dl>
+                    </div>
+                </div>
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                        <b>SNV</b>
+                        <b>7-100954830-C-G [0/1:./.:0/0]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs1310488669">rs1310488669</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.100</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000379458.9">MUC3A:ENST00000379458.9:c.3051C&gt;G:p.(=)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            <dd>No frequency data</dd>
+                            
+                        </dl>
+                    </div>
+                </div>
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                        <b>SNV</b>
+                        <b>7-100955826-T-G [0/1:0/1:0/0]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs1394171058">rs1394171058</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.100</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000379458.9">MUC3A:ENST00000379458.9:c.4047T&gt;G:p.(=)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            <dd>No frequency data</dd>
+                            
+                        </dl>
+                    </div>
+                </div>
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                        <b>SNV</b>
+                        <b>7-100955898-T-C [0/1:0/1:0/0]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs1346410915">rs1346410915</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.100</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000379458.9">MUC3A:ENST00000379458.9:c.4119T&gt;C:p.(=)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            <dd>No frequency data</dd>
+                            
+                        </dl>
+                    </div>
+                </div>
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                        <b>SNV</b>
+                        <b>7-100955934-C-T [0/1:0/1:0/0]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs1372154399">rs1372154399</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.100</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000379458.9">MUC3A:ENST00000379458.9:c.4155C&gt;T:p.(=)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            <dd>No frequency data</dd>
+                            
+                        </dl>
+                    </div>
+                </div>
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                        <b>SNV</b>
+                        <b>7-100955991-C-T [0/1:0/1:0/0]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs1213586128">rs1213586128</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.100</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000379458.9">MUC3A:ENST00000379458.9:c.4212C&gt;T:p.(=)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            <dd>No frequency data</dd>
+                            
+                        </dl>
+                    </div>
+                </div>
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                        <b>SNV</b>
+                        <b>7-100965843-G-A [0/1:0/0:0/0]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs67377634">rs67377634</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.100</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000379458.9">MUC3A:ENST00000379458.9:c.9588G&gt;A:p.(=)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            <dd>No frequency data</dd>
+                            
+                        </dl>
+                    </div>
+                </div>
+                <div class="row">
+                    <div class="col-sm-12">
+                        <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                        <b>SNV</b>
+                        <b>7-100965798-G-T [0/1:0/0:0/1]</b>
+                        
+                        
+                            <a href="https://www.ncbi.nlm.nih.gov/snp/rs35790618">rs35790618</a>
+                            
+                            
+                            
+                            
+                        
+                    </div>
+                    <!--                    <div class="col-sm-12">-->
+                    <!--                        <b>Exomiser ACMG: </b>-->
+                    <!--                        <th:bloc  th:with="moi =${geneScore.getModeOfInheritance()} , acmgClassification = ${variantEvaluation.acmgAssignmentForMoi(${moi})}"-->
+                    <!--                                  th:switch="${acmgClassification.toString()}">-->
+                    <!--                                    <span th:case="'BENIGN'" class="label label-success"-->
+                    <!--                                          th:text="${acmgClassification}">BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_BENIGN'" class="label label-info"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_BENIGN</span>-->
+                    <!--                            <span th:case="'LIKELY_PATHOGENIC'" class="label label-warning"-->
+                    <!--                                  th:text="${acmgClassification}">LIKELY_PATHOGENIC</span>-->
+                    <!--                            <span th:case="'PATHOGENIC'" class="label label-danger"-->
+                    <!--                                  th:text="${acmgClassification}">PATHOGENIC</span>-->
+                    <!--                            <span th:case="'UNCERTAIN_SIGNIFICANCE'" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">UNCERTAIN_SIGNIFICANCE</span>-->
+                    <!--                            <span th:case="*" class="label label-default"-->
+                    <!--                                  th:text="${acmgClassification}">NOT_AVAILABLE</span>-->
+                    <!--                            <b-->
+                    <!--                                    th:text="${acmgClassification.acmgCriteria()}">-->
+                    <!--                                [PVS1, BP2]-->
+                    <!--                            </b>-->
+                    <!--                        </th:bloc>-->
+                    <!--                    </div>-->
+                    
+                    <div class="col-sm-6">
+                        <b>Variant score: 0.100</b>
+                        
+                        <dl class="list-unstyled">
+                            <dt>Transcripts:</dt>
+                            <dd>
+                                
+                                <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000379458.9">MUC3A:ENST00000379458.9:c.9543G&gt;T:p.(=)</a>
+                                
+                            </dd>
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Pathogenicity Score: 1.00</b>-->
+                        <dl class="list-unstyled">
+                            <dt>Pathogenicity Data:</dt>
+                            
+                            <dd>No
+                                pathogenicity data
+                            </dd>
+                            
+                        </dl>
+                    </div>
+                    <div class="col-sm-3">
+                        <!--<b>Frequency Score: 0.95</b>-->
+                        <dl>
+                            <dt>Frequency Data:</dt>
+                            
+                            <dd>1000Genomes: 0.0200%</dd>
+                            <dd>TOPMed: 0.0200%</dd>
+                        </dl>
+                    </div>
+                </div>
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="CSRNP2" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000110925">CSRNP2</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.001</b>
+                    <data>(p=7.6E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.128</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=CSRNP2%0DPHKB&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to PHKB</a> and phenotypic similarity 0.686 to <a href="http://www.omim.org/entry/261750">Phosphorylase kinase deficiency of liver and muscle, autosomal recessive</a> associated with PHKB.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001744, Splenomegaly</dd><dd>HP:0001903, Anemia - HP:0001744, Splenomegaly</dd><dd>HP:0001541, Ascites - HP:0002240, Hepatomegaly</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001744, Splenomegaly</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001744, Splenomegaly</dd><dd>HP:0001396, Cholestasis - HP:0002240, Hepatomegaly</dd><dd>HP:0001410, Decreased liver function - HP:0002240, Hepatomegaly</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0002240, Hepatomegaly</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - HP:0001943, Hypoglycemia</dd><dd>HP:0003073, Hypoalbuminemia - HP:0002149, Hyperuricemia</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0002149, Hyperuricemia</dd><dd>HP:0001873, Thrombocytopenia - HP:0001744, Splenomegaly</dd><dd>HP:0002151, Increased serum lactate - HP:0001943, Hypoglycemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0006568, Increased hepatic glycogen content</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001744, Splenomegaly</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=CSRNP2%0DPHKB&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to PHKB</a> and phenotypic similarity 0.662 to mouse mutant of PHKB.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000599, enlarged liver</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - MP:0000599, enlarged liver</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0000598, abnormal liver morphology</dd><dd>HP:0001410, Decreased liver function - MP:0000598, abnormal liver morphology</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000598, abnormal liver morphology</dd><dd>HP:0001399, Hepatic failure - MP:0000598, abnormal liver morphology</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0001552, increased circulating triglyceride level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000598, abnormal liver morphology</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000598, abnormal liver morphology</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0010400, increased liver glycogen level</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.001</b>
+                                    <data>(p=7.6E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.128</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SPLICE_REGION_VARIANT</span>
+                            <b>SNV</b>
+                            <b>12-51064672-G-A [1/1:0/1:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs148790966">rs148790966</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.128</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000228515.6">CSRNP2:ENST00000228515.6:c.709-3C&gt;T:p.?</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.3592%</dd>
+                                    <dd>TOPMed: 0.0748%</dd>
+                                    <dd>ExAC EAS: 1.7751%</dd>
+                                    <dd>ExAC SAS: 0.0567%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0047%</dd>
+                                    <dd>gnomAD_E_EAS: 1.8941%</dd>
+                                    <dd>gnomAD_E_OTH: 0.1710%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0506%</dd>
+                                    <dd>gnomAD_G_AFR: 0.0229%</dd>
+                                    <dd>gnomAD_G_EAS: 1.9753%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="PLXNA3" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000130827">PLXNA3</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.001</b>
+                    <data>(p=7.7E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.122</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.241 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=PLXNA3">PLXNA3</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0008960, abnormal axon pruning</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0008960, abnormal axon pruning</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.331 to zebrafish mutant involving <a href="http://zfin.org/action/quicksearch/query?query=PLXNA3">PLXNA3</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - ZP:0012648, axon spinal cord increased branchiness, abnormal</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=PLXNA3%0DSEMA4D&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SEMA4D</a> and phenotypic similarity 0.727 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=171">Primary sclerosing cholangitis</a> associated with SEMA4D.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001433, Hepatosplenomegaly</dd><dd>HP:0001903, Anemia - HP:0001879, Abnormal eosinophil morphology</dd><dd>HP:0001541, Ascites - HP:0001541, Ascites</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001879, Abnormal eosinophil morphology</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001879, Abnormal eosinophil morphology</dd><dd>HP:0001396, Cholestasis - HP:0001396, Cholestasis</dd><dd>HP:0001410, Decreased liver function - HP:0100626, Chronic hepatic failure</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0001399, Hepatic failure - HP:0100626, Chronic hepatic failure</dd><dd>HP:0000938, Osteopenia - HP:0000938, Osteopenia</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001635, Congestive heart failure</dd><dd>HP:0200114, Metabolic alkalosis - HP:0001945, Fever</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003073, Hypoalbuminemia</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0100512, Low levels of vitamin D</dd><dd>HP:0001873, Thrombocytopenia - HP:0001879, Abnormal eosinophil morphology</dd><dd>HP:0002151, Increased serum lactate - HP:0003073, Hypoalbuminemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001394, Cirrhosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0100727, Histiocytosis</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001824, Weight loss</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=PLXNA3%0DSEMA4D&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SEMA4D</a> and phenotypic similarity 0.447 to mouse mutant of SEMA4D.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000691, enlarged spleen</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - MP:0000691, enlarged spleen</dd><dd>HP:0010972, Anemia of inadequate production - MP:0000691, enlarged spleen</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0010124, decreased bone mineral content</dd><dd>HP:0001396, Cholestasis - MP:0000691, enlarged spleen</dd><dd>HP:0001410, Decreased liver function - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0001399, Hepatic failure - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0000938, Osteopenia - MP:0010124, decreased bone mineral content</dd><dd>HP:0001642, Pulmonic stenosis - MP:0000274, enlarged heart</dd><dd>HP:0200114, Metabolic alkalosis - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0002968, increased circulating alkaline phosphatase level</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000691, enlarged spleen</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>X_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.001</b>
+                                    <data>(p=7.7E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.122</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>X-154464030-C-T [1/1:./.:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs369262880">rs369262880</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4_Moderate]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=2440101%5Balleleid%5D">(criteria provided, single submitter)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.122</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000369682.4">PLXNA3:ENST00000369682.4:c.1627C&gt;T:p.(Arg543Trp)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.123314135</dd>
+                                    
+                                    <dd>REVEL: 0.083</dd>
+                                    <dd>MVP: 0.123</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0208%</dd>
+                                    <dd>TOPMed: 0.0042%</dd>
+                                    <dd>UK10K: 0.0152%</dd>
+                                    <dd>ExAC AFR: 0.0315%</dd>
+                                    <dd>ExAC EAS: 0.1020%</dd>
+                                    <dd>ExAC NFE: 0.0031%</dd>
+                                    <dd>gnomAD_E_AFR: 0.0085%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0560%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0256%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0110%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="ZNF205" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000122386">ZNF205</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.001</b>
+                    <data>(p=7.8E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.509</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.096</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.376 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=ZNF205">ZNF205</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia - MP:0002874, decreased hemoglobin content</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0002874, decreased hemoglobin content</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005554, decreased circulating creatinine level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002874, decreased hemoglobin content</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0002874, decreased hemoglobin content</dd><dd>HP:0001873, Thrombocytopenia - MP:0002874, decreased hemoglobin content</dd><dd>HP:0002151, Increased serum lactate - MP:0005554, decreased circulating creatinine level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0002874, decreased hemoglobin content</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.509 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ZNF205%0DMEFV&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to MEFV</a> and phenotypic similarity 0.588 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=342">Familial Mediterranean fever</a> associated with MEFV.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001744, Splenomegaly</dd><dd>HP:0001903, Anemia - HP:0002716, Lymphadenopathy</dd><dd>HP:0001541, Ascites - HP:0001541, Ascites</dd><dd>HP:0010972, Anemia of inadequate production - HP:0002716, Lymphadenopathy</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0002716, Lymphadenopathy</dd><dd>HP:0001396, Cholestasis - HP:0006554, Acute hepatic failure</dd><dd>HP:0001410, Decreased liver function - HP:0006554, Acute hepatic failure</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0006554, Acute hepatic failure</dd><dd>HP:0000938, Osteopenia - HP:0001369, Arthritis</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001658, Myocardial infarction</dd><dd>HP:0200114, Metabolic alkalosis - HP:0001945, Fever</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - HP:0002716, Lymphadenopathy</dd><dd>HP:0002151, Increased serum lactate - HP:0001945, Fever</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0006554, Acute hepatic failure</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0002633, Vasculitis</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.509 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ZNF205%0DMEFV&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to MEFV</a> and phenotypic similarity 0.616 to mouse mutant of MEFV.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000691, enlarged spleen</dd><dd>HP:0001903, Anemia - MP:0001577, anemia</dd><dd>HP:0001541, Ascites - MP:0000691, enlarged spleen</dd><dd>HP:0010972, Anemia of inadequate production - MP:0001577, anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0000218, increased leukocyte cell number</dd><dd>HP:0001396, Cholestasis - MP:0001860, liver inflammation</dd><dd>HP:0001410, Decreased liver function - MP:0001860, liver inflammation</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0001860, liver inflammation</dd><dd>HP:0001399, Hepatic failure - MP:0001860, liver inflammation</dd><dd>HP:0000938, Osteopenia - MP:0002933, joint inflammation</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0008553, increased circulating tumor necrosis factor level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0008553, increased circulating tumor necrosis factor level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0008553, increased circulating tumor necrosis factor level</dd><dd>HP:0001873, Thrombocytopenia - MP:0000322, increased granulocyte number</dd><dd>HP:0002151, Increased serum lactate - MP:0008553, increased circulating tumor necrosis factor level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0001860, liver inflammation</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0001860, liver inflammation</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0001860, liver inflammation</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0005425, increased macrophage cell number</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001732, postnatal growth retardation</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.001</b>
+                                    <data>(p=7.8E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.509</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.096</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                            <b>SNV</b>
+                            <b>16-3119854-C-T [1/1:0/1:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs376806635">rs376806635</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.096</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000219091.9">ZNF205:ENST00000219091.9:c.1194C&gt;T:p.(=)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0000%</dd>
+                                    <dd>TOPMed: 0.0083%</dd>
+                                    <dd>ExAC AMR: 0.0087%</dd>
+                                    <dd>ExAC EAS: 0.1754%</dd>
+                                    <dd>ExAC NFE: 0.0015%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0030%</dd>
+                                    <dd>gnomAD_E_EAS: 0.1747%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0009%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0183%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0130%</dd>
+                                    <dd>gnomAD_G_EAS: 0.2469%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="PLXNB3" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000198753">PLXNB3</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.001</b>
+                    <data>(p=7.8E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.506</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.099</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Proximity score 0.506 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=PLXNB3%0DABCD3&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to ABCD3</a> and phenotypic similarity 0.682 to <a href="http://www.omim.org/entry/616278">?Bile acid synthesis defect, congenital, 5</a> associated with ABCD3.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001744, Splenomegaly</dd><dd>HP:0001903, Anemia - HP:0001891, Iron deficiency anemia</dd><dd>HP:0001541, Ascites - HP:0002240, Hepatomegaly</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001891, Iron deficiency anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001891, Iron deficiency anemia</dd><dd>HP:0001396, Cholestasis - HP:0000952, Jaundice</dd><dd>HP:0001410, Decreased liver function - HP:0001399, Hepatic failure</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0001399, Hepatic failure - HP:0001399, Hepatic failure</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001409, Portal hypertension</dd><dd>HP:0200114, Metabolic alkalosis - HP:0002904, Hyperbilirubinemia</dd><dd>HP:0003073, Hypoalbuminemia - HP:0002904, Hyperbilirubinemia</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0012202, Increased serum bile acid concentration</dd><dd>HP:0001873, Thrombocytopenia - HP:0001891, Iron deficiency anemia</dd><dd>HP:0002151, Increased serum lactate - HP:0002904, Hyperbilirubinemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001395, Hepatic fibrosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001891, Iron deficiency anemia</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.506 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=PLXNB3%0DABCD3&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to ABCD3</a> and phenotypic similarity 0.514 to mouse mutant of ABCD3.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000599, enlarged liver</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - MP:0000599, enlarged liver</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0004773, abnormal bile composition</dd><dd>HP:0001410, Decreased liver function - MP:0004773, abnormal bile composition</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0004773, abnormal bile composition</dd><dd>HP:0001399, Hepatic failure - MP:0004773, abnormal bile composition</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0004773, abnormal bile composition</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0004773, abnormal bile composition</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000599, enlarged liver</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>X_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.001</b>
+                                    <data>(p=7.8E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.506</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.099</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                            <b>SNV</b>
+                            <b>X-153770151-G-A [0/1:0/0:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs201004092">rs201004092</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.099</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000361971.10">PLXNB3:ENST00000361971.10:c.1689G&gt;A:p.(=)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0624%</dd>
+                                    <dd>TOPMed: 0.0087%</dd>
+                                    <dd>UK10K: 0.0152%</dd>
+                                    <dd>ExAC EAS: 0.0151%</dd>
+                                    <dd>ExAC NFE: 0.0148%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0078%</dd>
+                                    <dd>gnomAD_E_FIN: 0.0061%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0150%</dd>
+                                    <dd>gnomAD_G_NFE: 0.0855%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="AGAP4" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000188234">AGAP4</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.001</b>
+                    <data>(p=7.8E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.104</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=AGAP4%0DSEC23B&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SEC23B</a> and phenotypic similarity 0.605 to <a href="http://www.omim.org/entry/224100">Dyserythropoietic anemia, congenital, type II</a> associated with SEC23B.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001744, Splenomegaly</dd><dd>HP:0001903, Anemia - HP:0001923, Reticulocytosis</dd><dd>HP:0001541, Ascites - HP:0001744, Splenomegaly</dd><dd>HP:0010972, Anemia of inadequate production - HP:0010972, Anemia of inadequate production</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0010972, Anemia of inadequate production</dd><dd>HP:0001396, Cholestasis - HP:0000952, Jaundice</dd><dd>HP:0001410, Decreased liver function - HP:0001081, Cholelithiasis</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0003655, Reduced level of N-acetylglucosaminyltransferase II</dd><dd>HP:0001399, Hepatic failure - HP:0001081, Cholelithiasis</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003655, Reduced level of N-acetylglucosaminyltransferase II</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0003655, Reduced level of N-acetylglucosaminyltransferase II</dd><dd>HP:0001873, Thrombocytopenia - HP:0001923, Reticulocytosis</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0003655, Reduced level of N-acetylglucosaminyltransferase II</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0003655, Reduced level of N-acetylglucosaminyltransferase II</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001081, Cholelithiasis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0010972, Anemia of inadequate production</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=AGAP4%0DSEC23B&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SEC23B</a> and phenotypic similarity 0.351 to mouse mutant of SEC23B.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0009165, abnormal endocrine pancreas morphology</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0010148, abnormal exocrine pancreas physiology</dd><dd>HP:0001410, Decreased liver function - MP:0010148, abnormal exocrine pancreas physiology</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0010148, abnormal exocrine pancreas physiology</dd><dd>HP:0001399, Hepatic failure - MP:0010148, abnormal exocrine pancreas physiology</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0010148, abnormal exocrine pancreas physiology</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0010148, abnormal exocrine pancreas physiology</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0009177, decreased pancreatic alpha cell number</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.001</b>
+                                    <data>(p=7.8E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.104</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>10-45826783-T-C [0/1:0/0:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs1282313249">rs1282313249</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4_Moderate]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.112</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000616763.6">AGAP4:ENST00000616763.6:c.1193A&gt;G:p.(Asn398Ser)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.11264884</dd>
+                                    
+                                    <dd>REVEL: 0.090</dd>
+                                    <dd>MVP: 0.113</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>gnomAD_E_EAS: 0.0530%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0579%</dd>
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>10-45826199-G-A [0/1:./.:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs1483564807">rs1483564807</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[PM2_Supporting, BP4_Moderate]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.097</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000616763.6">AGAP4:ENST00000616763.6:c.1777C&gt;T:p.(Arg593Trp)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.097</dd>
+                                    
+                                    <dd>REVEL: 0.097</dd>
+                                    <dd>MVP: 0.095</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.001</b>
+                                    <data>(p=7.9E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.097</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>10-45826199-G-A [0/1:./.:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs1483564807">rs1483564807</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[PM2_Supporting, BP4_Moderate]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.097</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000616763.6">AGAP4:ENST00000616763.6:c.1777C&gt;T:p.(Arg593Trp)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.097</dd>
+                                    
+                                    <dd>REVEL: 0.097</dd>
+                                    <dd>MVP: 0.095</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="VCX3B" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000205642">VCX3B</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.001</b>
+                    <data>(p=7.9E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.099</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=VCX3B%0DIRS1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to IRS1</a> and phenotypic similarity 0.258 to <a href="http://www.omim.org/entry/125853">Type 2 diabetes mellitus, susceptibility to</a> associated with IRS1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0005978, Type II diabetes mellitus</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0005978, Type II diabetes mellitus</dd><dd>HP:0001410, Decreased liver function - HP:0005978, Type II diabetes mellitus</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0005978, Type II diabetes mellitus</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - HP:0000855, Insulin resistance</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0000855, Insulin resistance</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0005978, Type II diabetes mellitus</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0031819, Increased waist to hip ratio</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=VCX3B%0DIRS1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to IRS1</a> and phenotypic similarity 0.638 to mouse mutant of IRS1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0008396, abnormal osteoclast differentiation</dd><dd>HP:0001903, Anemia - MP:0008396, abnormal osteoclast differentiation</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0008396, abnormal osteoclast differentiation</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0004989, decreased osteoblast cell number</dd><dd>HP:0001396, Cholestasis - MP:0003059, decreased insulin secretion</dd><dd>HP:0001410, Decreased liver function - MP:0003059, decreased insulin secretion</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0003059, decreased insulin secretion</dd><dd>HP:0001399, Hepatic failure - MP:0003059, decreased insulin secretion</dd><dd>HP:0000938, Osteopenia - MP:0000063, decreased bone mineral density</dd><dd>HP:0001642, Pulmonic stenosis - MP:0006143, increased systemic arterial diastolic blood pressure</dd><dd>HP:0200114, Metabolic alkalosis - MP:0002079, increased circulating insulin level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002079, increased circulating insulin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0000186, decreased circulating HDL cholesterol level</dd><dd>HP:0001873, Thrombocytopenia - MP:0008396, abnormal osteoclast differentiation</dd><dd>HP:0002151, Increased serum lactate - MP:0001554, increased circulating free fatty acids level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0003059, decreased insulin secretion</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0003059, decreased insulin secretion</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0003059, decreased insulin secretion</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0008396, abnormal osteoclast differentiation</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001262, decreased body weight</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=VCX3B%0DIRS1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to IRS1</a> and phenotypic similarity 0.300 to fish mutant of IRS1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - ZP:0005798, developmental growth decreased rate, abnormal</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>X_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.001</b>
+                                    <data>(p=7.9E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.099</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                            <b>SNV</b>
+                            <b>X-8466206-C-T [0/1:0/0:./.]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs201851798">rs201851798</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.099</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000381032.6">VCX3B:ENST00000381032.6:c.564C&gt;T:p.(=)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>gnomAD_E_AFR: 0.0130%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0092%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0513%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0030%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0069%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>X_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.001</b>
+                                    <data>(p=7.9E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.099</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                            <b>SNV</b>
+                            <b>X-8466206-C-T [0/1:0/0:./.]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs201851798">rs201851798</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.099</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000381032.6">VCX3B:ENST00000381032.6:c.564C&gt;T:p.(=)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>gnomAD_E_AFR: 0.0130%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0092%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0513%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0030%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0069%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="ADAMTS5" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000154736">ADAMTS5</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.001</b>
+                    <data>(p=7.9E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.098</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.175 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=ADAMTS5">ADAMTS5</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia - MP:0003436, decreased susceptibility to induced arthritis</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ADAMTS5%0DIL18BP&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to IL18BP</a> and phenotypic similarity 0.601 to <a href="http://www.omim.org/entry/618549">?Hepatitis, fulminant viral, susceptibility to</a> associated with IL18BP.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0002240, Hepatomegaly</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - HP:0002240, Hepatomegaly</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0000952, Jaundice</dd><dd>HP:0001410, Decreased liver function - HP:0001399, Hepatic failure</dd><dd>HP:0002910, Elevated hepatic transaminase - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0001399, Hepatic failure - HP:0001399, Hepatic failure</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0000225, Gingival bleeding</dd><dd>HP:0200114, Metabolic alkalosis - HP:0100651, Type I diabetes mellitus</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0100651, Type I diabetes mellitus</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - HP:0002910, Elevated hepatic transaminase</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0002240, Hepatomegaly</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=ADAMTS5%0DIL18BP&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to IL18BP</a> and phenotypic similarity 0.562 to mouse mutant of IL18BP.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000599, enlarged liver</dd><dd>HP:0001903, Anemia - MP:0005152, pancytopenia</dd><dd>HP:0001541, Ascites - MP:0000599, enlarged liver</dd><dd>HP:0010972, Anemia of inadequate production - MP:0005152, pancytopenia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0005152, pancytopenia</dd><dd>HP:0001396, Cholestasis - MP:0000599, enlarged liver</dd><dd>HP:0001410, Decreased liver function - MP:0000599, enlarged liver</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000599, enlarged liver</dd><dd>HP:0001399, Hepatic failure - MP:0000599, enlarged liver</dd><dd>HP:0000938, Osteopenia - MP:0005152, pancytopenia</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0008577, increased circulating interferon-gamma level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0011890, increased circulating ferritin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0011890, increased circulating ferritin level</dd><dd>HP:0001873, Thrombocytopenia - MP:0005152, pancytopenia</dd><dd>HP:0002151, Increased serum lactate - MP:0008577, increased circulating interferon-gamma level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000599, enlarged liver</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000599, enlarged liver</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0000599, enlarged liver</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0005425, increased macrophage cell number</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001263, weight loss</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.001</b>
+                                    <data>(p=7.9E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.098</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                            <b>SNV</b>
+                            <b>21-26924251-A-G [1/1:0/1:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs201648090">rs201648090</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.098</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000284987.6">ADAMTS5:ENST00000284987.6:c.2595T&gt;C:p.(=)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.1093%</dd>
+                                    <dd>TOPMed: 0.0042%</dd>
+                                    <dd>ExAC EAS: 0.1387%</dd>
+                                    <dd>ExAC SAS: 0.0182%</dd>
+                                    <dd>gnomAD_E_EAS: 0.1160%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0009%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0182%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0162%</dd>
+                                    <dd>gnomAD_G_AFR: 0.0115%</dd>
+                                    <dd>gnomAD_G_EAS: 0.0617%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="CACNA1E" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000198216">CACNA1E</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.001</b>
+                    <data>(p=7.9E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.251</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.378</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.317 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=CACNA1E">CACNA1E</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0009177, decreased pancreatic alpha cell number</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0009177, decreased pancreatic alpha cell number</dd><dd>HP:0001410, Decreased liver function - MP:0003562, abnormal pancreatic beta cell physiology</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0003562, abnormal pancreatic beta cell physiology</dd><dd>HP:0001399, Hepatic failure - MP:0003562, abnormal pancreatic beta cell physiology</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002696, decreased circulating glucagon level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0002696, decreased circulating glucagon level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0003562, abnormal pancreatic beta cell physiology</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0003562, abnormal pancreatic beta cell physiology</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0003565, abnormal glucagon secretion</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.502 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=CACNA1E%0DCLCN2&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to CLCN2</a> and phenotypic similarity 0.612 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=404">Familial hyperaldosteronism type II</a> associated with CLCN2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0008221, Adrenal hyperplasia</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0008221, Adrenal hyperplasia</dd><dd>HP:0001410, Decreased liver function - HP:0011740, Glucocortocoid-insensitive primary hyperaldosteronism</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0011740, Glucocortocoid-insensitive primary hyperaldosteronism</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0000822, Hypertension</dd><dd>HP:0200114, Metabolic alkalosis - HP:0200114, Metabolic alkalosis</dd><dd>HP:0003073, Hypoalbuminemia - HP:0040084, Abnormal circulating renin</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0011740, Glucocortocoid-insensitive primary hyperaldosteronism</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0200114, Metabolic alkalosis</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0008221, Adrenal hyperplasia</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0002170, Intracranial hemorrhage</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.502 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=CACNA1E%0DCLCN2&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to CLCN2</a> and phenotypic similarity 0.386 to mouse mutant of CLCN2.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0004109, abnormal Sertoli cell development</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0031384, impaired blood-brain barrier function</dd><dd>HP:0200114, Metabolic alkalosis - MP:0003352, increased circulating renin level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0003352, increased circulating renin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0003352, increased circulating renin level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0003352, increased circulating renin level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0000955, abnormal spinal cord morphology</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dl>
+<dt>Known diseases - observed variants incompatible with mode of inheritance:</dt>
+<dd><a href="http://www.omim.org/entry/618285">OMIM:618285</a> Developmental and epileptic encephalopathy 69 - autosomal dominant</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.001</b>
+                                    <data>(p=7.9E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.251</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.378</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>1-181733741-G-A [0/1:0/1:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs768308084">rs768308084</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=1448977%5Balleleid%5D">(criteria provided, multiple submitters, no conflicts)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.657</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000367573.7">CACNA1E:ENST00000367573.7:c.3253G&gt;A:p.(Val1085Met)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.6580741</dd>
+                                    
+                                    <dd>REVEL: 0.374</dd>
+                                    <dd>MVP: 0.658</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>TOPMed: 0.0008%</dd>
+                                    <dd>ExAC FIN: 0.0164%</dd>
+                                    <dd>ExAC NFE: 0.0033%</dd>
+                                    <dd>gnomAD_E_FIN: 0.0051%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0023%</dd>
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                            <b>SNV</b>
+                            <b>1-181762642-C-T [0/1:0/0:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs549521037">rs549521037</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP6]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=2140204%5Balleleid%5D">(criteria provided, single submitter)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.100</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000367573.7">CACNA1E:ENST00000367573.7:c.4674C&gt;T:p.(=)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0156%</dd>
+                                    <dd>TOPMed: 0.0004%</dd>
+                                    <dd>ExAC EAS: 0.0236%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0178%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0187%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="MAGEC1" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000155495">MAGEC1</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.001</b>
+                    <data>(p=8.0E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.090</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=MAGEC1%0DSMC5&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SMC5</a> and phenotypic similarity 0.561 to <a href="http://www.omim.org/entry/620185">Atelis syndrome 2</a> associated with SMC5.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0000771, Gynecomastia</dd><dd>HP:0001903, Anemia - HP:0001903, Anemia</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001903, Anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0001903, Anemia</dd><dd>HP:0001396, Cholestasis - HP:0002925, Elevated circulating thyroid-stimulating hormone concentration</dd><dd>HP:0001410, Decreased liver function - HP:0002925, Elevated circulating thyroid-stimulating hormone concentration</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0002925, Elevated circulating thyroid-stimulating hormone concentration</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0001642, Pulmonic stenosis</dd><dd>HP:0200114, Metabolic alkalosis - HP:0000842, Hyperinsulinemia</dd><dd>HP:0003073, Hypoalbuminemia - HP:0000842, Hyperinsulinemia</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0000842, Hyperinsulinemia</dd><dd>HP:0001873, Thrombocytopenia - HP:0001873, Thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate - HP:0000842, Hyperinsulinemia</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0000842, Hyperinsulinemia</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001903, Anemia</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=MAGEC1%0DSMC5&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SMC5</a> and phenotypic similarity 0.602 to mouse mutant of SMC5.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0005011, increased eosinophil cell number</dd><dd>HP:0001903, Anemia - MP:0002875, decreased erythrocyte cell number</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - MP:0005011, increased eosinophil cell number</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0005016, decreased lymphocyte cell number</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005344, increased circulating bilirubin level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0000186, decreased circulating HDL cholesterol level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0000186, decreased circulating HDL cholesterol level</dd><dd>HP:0001873, Thrombocytopenia - MP:0003179, thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate - MP:0005344, increased circulating bilirubin level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0005560, decreased circulating glucose level</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0000219, increased neutrophil cell number</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>X_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.001</b>
+                                    <data>(p=8.0E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.090</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>X-141905936-A-C [0/1:0/0:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs80314937">rs80314937</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4_Strong]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.090</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000285879.5">MAGEC1:ENST00000285879.5:c.532A&gt;C:p.(Ile178Leu)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.10462268</dd>
+                                    
+                                    <dd>REVEL: 0.015</dd>
+                                    <dd>MVP: 0.105</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>ExAC AFR: 0.3339%</dd>
+                                    <dd>ExAC AMR: 0.0562%</dd>
+                                    <dd>ExAC EAS: 0.0405%</dd>
+                                    <dd>ExAC FIN: 0.0387%</dd>
+                                    <dd>ExAC NFE: 0.0702%</dd>
+                                    <dd>ExAC OTH: 0.4651%</dd>
+                                    <dd>ExAC SAS: 0.0859%</dd>
+                                    <dd>gnomAD_E_AFR: 0.2972%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0556%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0889%</dd>
+                                    <dd>gnomAD_E_FIN: 0.0794%</dd>
+                                    <dd>gnomAD_E_NFE: 0.1027%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0943%</dd>
+                                    <dd>gnomAD_E_SAS: 0.1411%</dd>
+                                    <dd>gnomAD_G_AFR: 0.7056%</dd>
+                                    <dd>gnomAD_G_AMR: 0.5168%</dd>
+                                    <dd>gnomAD_G_FIN: 0.1143%</dd>
+                                    <dd>gnomAD_G_NFE: 0.0921%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="LONRF3" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000175556">LONRF3</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.001</b>
+                    <data>(p=8.2E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.071</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.302 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=LONRF3">LONRF3</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0001554, increased circulating free fatty acids level</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0001554, increased circulating free fatty acids level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0001554, increased circulating free fatty acids level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=LONRF3%0DBBS4&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to BBS4</a> and phenotypic similarity 0.312 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=110">Bardet-Biedl syndrome</a> associated with BBS4.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001395, Hepatic fibrosis</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0001395, Hepatic fibrosis</dd><dd>HP:0001410, Decreased liver function - HP:0001395, Hepatic fibrosis</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0001395, Hepatic fibrosis</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0000822, Hypertension</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001395, Hepatic fibrosis</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001513, Obesity</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=LONRF3%0DBBS4&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to BBS4</a> and phenotypic similarity 0.634 to mouse mutant of BBS4.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0000599, enlarged liver</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - MP:0000599, enlarged liver</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0000609, abnormal liver physiology</dd><dd>HP:0001410, Decreased liver function - MP:0000609, abnormal liver physiology</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0000609, abnormal liver physiology</dd><dd>HP:0001399, Hepatic failure - MP:0000609, abnormal liver physiology</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005343, increased circulating aspartate transaminase level</dd><dd>HP:0003073, Hypoalbuminemia - MP:0002941, increased circulating alanine transaminase level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0001556, increased circulating HDL cholesterol level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0005344, increased circulating bilirubin level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0000609, abnormal liver physiology</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0000609, abnormal liver physiology</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0003729, abnormal photoreceptor outer segment morphology</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0002628, hepatic steatosis</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001262, decreased body weight</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=LONRF3%0DBBS4&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to BBS4</a> and phenotypic similarity 0.270 to fish mutant of BBS4.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - ZP:0018684, exocrine pancreas decreased area, abnormal</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - ZP:0018684, exocrine pancreas decreased area, abnormal</dd><dd>HP:0001410, Decreased liver function - ZP:0018684, exocrine pancreas decreased area, abnormal</dd><dd>HP:0002910, Elevated hepatic transaminase - ZP:0018684, exocrine pancreas decreased area, abnormal</dd><dd>HP:0001399, Hepatic failure - ZP:0018684, exocrine pancreas decreased area, abnormal</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - ZP:0018684, exocrine pancreas decreased area, abnormal</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - ZP:0018684, exocrine pancreas decreased area, abnormal</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - ZP:0006380, photoreceptor cell outer segment organization disrupted, abnormal</dd><dd>HP:0006568, Increased hepatic glycogen content - ZP:0018684, exocrine pancreas decreased area, abnormal</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>X_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.001</b>
+                                    <data>(p=8.2E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.071</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                            <b>SNV</b>
+                            <b>X-118978451-G-A [0/1:0/0:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs140224937">rs140224937</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.071</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000371628.8">LONRF3:ENST00000371628.8:c.924G&gt;A:p.(=)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.1873%</dd>
+                                    <dd>TOPMed: 0.1322%</dd>
+                                    <dd>UK10K: 0.0303%</dd>
+                                    <dd>ESP AA: 0.2868%</dd>
+                                    <dd>ESP All: 0.1041%</dd>
+                                    <dd>ExAC AFR: 0.2820%</dd>
+                                    <dd>ExAC AMR: 0.0322%</dd>
+                                    <dd>ExAC EAS: 0.0151%</dd>
+                                    <dd>ExAC NFE: 0.0125%</dd>
+                                    <dd>ExAC SAS: 1.1387%</dd>
+                                    <dd>gnomAD_E_AFR: 0.3189%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0114%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0078%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0063%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0496%</dd>
+                                    <dd>gnomAD_E_SAS: 1.1526%</dd>
+                                    <dd>gnomAD_G_AFR: 0.3787%</dd>
+                                    <dd>gnomAD_G_OTH: 0.2789%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="SNX29" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000048471">SNX29</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.000</b>
+                    <data>(p=8.3E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.156</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.442</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.156 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=SNX29">SNX29</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0005333, decreased heart rate</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - MP:0004738, abnormal auditory brainstem response</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.000</b>
+                                    <data>(p=8.3E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.156</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.442</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SPLICE_REGION_VARIANT</span>
+                            <b>SNV</b>
+                            <b>16-12568499-C-G [0/1:0/1:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs757805840">rs757805840</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.798</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000566228.6">SNX29:ENST00000566228.6:c.2319-7C&gt;G:p.?</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>ExAC AMR: 0.0173%</dd>
+                                    <dd>gnomAD_E_AMR: 0.0030%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0009%</dd>
+                                </dl>
+                            </div>
+                        </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                            <b>SNV</b>
+                            <b>16-12052013-C-T [0/1:0/0:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs148525738">rs148525738</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.085</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000566228.6">SNX29:ENST00000566228.6:c.915C&gt;T:p.(=)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.1093%</dd>
+                                    <dd>TOPMed: 0.0185%</dd>
+                                    <dd>ESP EA: 0.0233%</dd>
+                                    <dd>ESP All: 0.0154%</dd>
+                                    <dd>ExAC EAS: 0.4507%</dd>
+                                    <dd>ExAC NFE: 0.0030%</dd>
+                                    <dd>gnomAD_E_EAS: 0.4812%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0054%</dd>
+                                    <dd>gnomAD_G_AFR: 0.0229%</dd>
+                                    <dd>gnomAD_G_EAS: 0.7398%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="VCX3A" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000169059">VCX3A</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.000</b>
+                    <data>(p=8.4E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.500</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.040</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=VCX3A%0DPARN&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to PARN</a> and phenotypic similarity 0.640 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=1775">Dyskeratosis congenita</a> associated with PARN.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0001744, Splenomegaly</dd><dd>HP:0001903, Anemia - HP:0001903, Anemia</dd><dd>HP:0001541, Ascites - HP:0002240, Hepatomegaly</dd><dd>HP:0010972, Anemia of inadequate production - HP:0001903, Anemia</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - HP:0005528, Bone marrow hypocellularity</dd><dd>HP:0001396, Cholestasis - HP:0001399, Hepatic failure</dd><dd>HP:0001410, Decreased liver function - HP:0001399, Hepatic failure</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0001399, Hepatic failure</dd><dd>HP:0000938, Osteopenia - HP:0000939, Osteoporosis</dd><dd>HP:0001642, Pulmonic stenosis - HP:0100585, Telangiectasia of the skin</dd><dd>HP:0200114, Metabolic alkalosis - HP:0000819, Diabetes mellitus</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - HP:0001873, Thrombocytopenia</dd><dd>HP:0002151, Increased serum lactate - HP:0000819, Diabetes mellitus</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0001394, Cirrhosis</dd><dd>HP:0004333, Bone-marrow foam cells - HP:0001874, Abnormality of neutrophils</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.500 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=VCX3A%0DPARN&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to PARN</a> and phenotypic similarity 0.324 to fish mutant of PARN.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - ZP:0000451, hemopoiesis disrupted, abnormal</dd><dd>HP:0001903, Anemia - ZP:0000451, hemopoiesis disrupted, abnormal</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production - ZP:0000451, hemopoiesis disrupted, abnormal</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - ZP:0000451, hemopoiesis disrupted, abnormal</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia - ZP:0000451, hemopoiesis disrupted, abnormal</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells - ZP:0000451, hemopoiesis disrupted, abnormal</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>X_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.000</b>
+                                    <data>(p=8.4E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.500</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.040</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>X-6533948-C-T [0/1:0/0:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs753646427">rs753646427</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[BP4_Strong]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.040</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000381089.7">VCX3A:ENST00000381089.7:c.358G&gt;A:p.(Val120Met)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.043077525</dd>
+                                    
+                                    <dd>REVEL: 0.012</dd>
+                                    <dd>MVP: 0.043</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>gnomAD_E_AFR: 0.0189%</dd>
+                                    <dd>gnomAD_E_EAS: 0.0125%</dd>
+                                    <dd>gnomAD_E_FIN: 0.0419%</dd>
+                                    <dd>gnomAD_E_NFE: 0.0192%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0375%</dd>
+                                    <dd>gnomAD_G_AFR: 0.1553%</dd>
+                                    <dd>gnomAD_G_AMR: 0.3960%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="NBPF10" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000271425">NBPF10</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.000</b>
+                    <data>(p=8.5E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.000</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.600</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>No phenotype or PPI evidence</dt></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.000</b>
+                                    <data>(p=8.5E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.000</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.600</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>1-146121575-G-C [0/1:0/0:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs1299657693">rs1299657693</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.600</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000583866.9">NBPF10:ENST00000583866.9:c.2681C&gt;G:p.(Thr894Ser)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.000</b>
+                                    <data>(p=8.5E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.000</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.600</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>1-146069569-C-T [1/1:0/1:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs374175846">rs374175846</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[PM2_Supporting]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.600</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000583866.9">NBPF10:ENST00000583866.9:c.10784G&gt;A:p.(Arg3595His)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="MUC17" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000169876">MUC17</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.000</b>
+                    <data>(p=8.6E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.506</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.014</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Proximity score 0.506 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=MUC17%0DGALNT1&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to GALNT1</a> and phenotypic similarity 0.745 to mouse mutant of GALNT1.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0001903, Anemia - MP:0002607, decreased basophil cell number</dd><dd>HP:0001541, Ascites - MP:0005606, increased bleeding time</dd><dd>HP:0010972, Anemia of inadequate production - MP:0005012, decreased eosinophil cell number</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology - MP:0002607, decreased basophil cell number</dd><dd>HP:0001396, Cholestasis - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0001410, Decreased liver function - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0001399, Hepatic failure - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - MP:0006128, pulmonary valve stenosis</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia - MP:0005419, decreased circulating serum albumin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - MP:0005419, decreased circulating serum albumin level</dd><dd>HP:0001873, Thrombocytopenia - MP:0002607, decreased basophil cell number</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0008482, decreased spleen germinal center number</dd><dd>HP:0004333, Bone-marrow foam cells - MP:0010470, dilated ascending aorta</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>PhenIX semantic similarity score: 0.00 (p-value: 1.000000)</dt></dl><dt>No known disease</dt>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_DOMINANT</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.000</b>
+                                    <data>(p=8.6E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.506</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.014</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">MISSENSE_VARIANT</span>
+                            <b>SNV</b>
+                            <b>7-101037135-T-A [0/1:./.:0/0]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs371070576">rs371070576</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                <span class="label label-info">LIKELY_BENIGN</span>
+                                
+                                
+                                
+                                
+                                <b>[PM2_Supporting, BP4_Strong]</b>
+                            
+                        </div>
+                        
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.014</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000306151.9">MUC17:ENST00000306151.9:c.5719T&gt;A:p.(Ser1907Thr)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    <dd>Best Score: 0.013882241</dd>
+                                    
+                                    <dd>REVEL: 0.006</dd>
+                                    <dd>MVP: 0.014</dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    <dd>No frequency data</dd>
+                                    
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+    <div class="panel panel-default">
+        <div id="SCN8A" class="panel-heading">
+            <div class="row">
+                <div class="col-sm-3">
+                    <h4>
+                        <b></b>
+                        <a href="https://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000196876">SCN8A</a>
+                        
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Exomiser Score: <b>0.000</b>
+                    <data>(p=8.7E-1)</data>
+                    </h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Phenotype Score: <b>0.505</b></h4>
+                </div>
+                <div class="col-sm-3">
+                    <h4>Variant Score: <b>0.000</b></h4>
+                </div>
+            </div>
+        </div>
+        <div class="panel-body">
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Phenotype matches:</b>
+                </div>
+            </div>
+            <div class="row">
+                <div class="col-sm-12">
+                    <dl><dt>Phenotypic similarity 0.327 to <a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=442835">Non-specific early-onset epileptic encephalopathy</a> associated with SCN8A.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - HP:0000648, Optic atrophy</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - HP:0001508, Failure to thrive</dd></dl><dl><dt>Phenotypic similarity 0.355 to mouse mutant involving <a href="http://www.informatics.jax.org/searchtool/Search.do?query=SCN8A">SCN8A</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - MP:0004952, increased spleen weight</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites - MP:0004952, increased spleen weight</dd><dd>HP:0010972, Anemia of inadequate production - MP:0004952, increased spleen weight</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0004952, increased spleen weight</dd><dd>HP:0001410, Decreased liver function - MP:0004952, increased spleen weight</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0004952, increased spleen weight</dd><dd>HP:0001399, Hepatic failure - MP:0004952, increased spleen weight</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0004952, increased spleen weight</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0004952, increased spleen weight</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - MP:0004952, increased spleen weight</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Phenotypic similarity 0.202 to zebrafish mutant involving <a href="http://zfin.org/action/quicksearch/query?query=SCN8A">SCN8A</a>.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis -</dd><dd>HP:0001410, Decreased liver function -</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure -</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis -</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate -</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology - ZP:0000834, neuron differentiation process quality, abnormal</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.505 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=SCN8A%0DSCNN1G&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SCNN1G</a> and phenotypic similarity 0.603 to <a href="http://www.omim.org/entry/618114">Liddle syndrome 2</a> associated with SCNN1G.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly - HP:0003351, Decreased circulating renin level</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - HP:0003351, Decreased circulating renin level</dd><dd>HP:0001410, Decreased liver function - HP:0004319, Decreased circulating aldosterone level</dd><dd>HP:0002910, Elevated hepatic transaminase -</dd><dd>HP:0001399, Hepatic failure - HP:0004319, Decreased circulating aldosterone level</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis - HP:0000822, Hypertension</dd><dd>HP:0200114, Metabolic alkalosis - HP:0200114, Metabolic alkalosis</dd><dd>HP:0003073, Hypoalbuminemia - HP:0003351, Decreased circulating renin level</dd><dd>HP:0003233, Decreased HDL cholesterol concentration - HP:0004319, Decreased circulating aldosterone level</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - HP:0200114, Metabolic alkalosis</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration -</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration -</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content - HP:0003351, Decreased circulating renin level</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy -</dd></dl><dl><dt>Proximity score 0.505 in <a href="http://version10.string-db.org/newstring_cgi/show_network_section.pl?identifiers=SCN8A%0DSCNN1G&required_score=700&network_flavor=evidence&species=9606&limit=20">interactome to SCNN1G</a> and phenotypic similarity 0.354 to mouse mutant of SCNN1G.</dt><dt>Best Phenotype Matches:</dt><dd>HP:0000007, Autosomal recessive inheritance -</dd><dd>HP:0001433, Hepatosplenomegaly -</dd><dd>HP:0001903, Anemia -</dd><dd>HP:0001541, Ascites -</dd><dd>HP:0010972, Anemia of inadequate production -</dd><dd>HP:0005561, Abnormality of bone marrow cell morphology -</dd><dd>HP:0001396, Cholestasis - MP:0014206, decreased intestinal epithelial sodium ion transmembrane transport</dd><dd>HP:0001410, Decreased liver function - MP:0014206, decreased intestinal epithelial sodium ion transmembrane transport</dd><dd>HP:0002910, Elevated hepatic transaminase - MP:0014206, decreased intestinal epithelial sodium ion transmembrane transport</dd><dd>HP:0001399, Hepatic failure - MP:0014206, decreased intestinal epithelial sodium ion transmembrane transport</dd><dd>HP:0000938, Osteopenia -</dd><dd>HP:0001642, Pulmonic stenosis -</dd><dd>HP:0200114, Metabolic alkalosis - MP:0005618, decreased urine potassium level</dd><dd>HP:0003073, Hypoalbuminemia -</dd><dd>HP:0003233, Decreased HDL cholesterol concentration -</dd><dd>HP:0001873, Thrombocytopenia -</dd><dd>HP:0002151, Increased serum lactate - MP:0005627, increased circulating potassium level</dd><dd>HP:0031964, Elevated circulating alanine aminotransferase concentration - MP:0014206, decreased intestinal epithelial sodium ion transmembrane transport</dd><dd>HP:0031956, Elevated circulating aspartate aminotransferase concentration - MP:0014206, decreased intestinal epithelial sodium ion transmembrane transport</dd><dd>HP:0002366, Abnormal lower motor neuron morphology -</dd><dd>HP:0006568, Increased hepatic glycogen content -</dd><dd>HP:0004333, Bone-marrow foam cells -</dd><dd>HP:0001531, Failure to thrive in infancy - MP:0001263, weight loss</dd></dl><dl><dt>PhenIX semantic similarity score: 0.41 (p-value: 0.856380)</dt></dl><dl>
+<dt>Known diseases - observed variants incompatible with mode of inheritance:</dt>
+<dd><a href="http://www.omim.org/entry/614306">OMIM:614306</a> Cognitive impairment with or without cerebellar ataxia - autosomal dominant</dd>
+<dd><a href="http://www.omim.org/entry/614558">OMIM:614558</a> Developmental and epileptic encephalopathy 13 - autosomal dominant</dd>
+<dd><a href="http://www.omim.org/entry/617080">OMIM:617080</a> Seizures, benign familial infantile, 5 - autosomal dominant</dd>
+<dd><a href="http://www.omim.org/entry/618364">OMIM:618364</a> ?Myoclonus, familial, 2 (unconfirmed)</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=306">ORPHA:306</a> Benign familial infantile epilepsy - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=31709">ORPHA:31709</a> Infantile convulsions and choreoathetosis - autosomal dominant</dd>
+<dd><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=442835">ORPHA:442835</a> Non-specific early-onset epileptic encephalopathy - autosomal dominant</dd>
+</dl>
+                </div>
+            </div>
+
+            <div class="row">
+                <div class="col-sm-12">
+                    <b>Gene scores under compatible inheritance modes:</b>
+                </div>
+            </div>
+
+            
+
+            <div class="panel panel-default">
+
+                <!--<div th:if="${not #lists.isEmpty(geneScore.getContributingVariants())}">-->
+                <div class="panel-heading">
+                    <div class="row">
+                        <div class="col-sm-3">
+                            <h4>AUTOSOMAL_RECESSIVE</h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Exomiser Score:
+                                    <b>0.000</b>
+                                    <data>(p=9.3E-1)</data>
+                                </h4>
+                            </div>
+                            <div class="col-sm-3">
+                                <h4>Phenotype Score: <b>0.253</b>
+                                </h4>
+                            </div>
+                        <div class="col-sm-3">
+                            <h4>Variant Score: <b>0.097</b>
+                            </h4>
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>
+                                No phenotype matches to diseases with this MOI.
+                            </b>
+                            
+                        </div>
+                    </div>
+                </div>
+                <div class="panel-body">
+                    <div class="row">
+                        <div class="col-sm-12">
+                            <b>Variants contributing to score:</b>
+                        </div>
+                    </div>
+                    <div class="row">
+                        <div class="col-sm-12">
+                                <span class="label label-danger">SYNONYMOUS_VARIANT</span>
+                            <b>SNV</b>
+                            <b>12-51663087-G-T [1/1:0/1:0/1]</b>
+                            
+                            
+                                <a href="https://www.ncbi.nlm.nih.gov/snp/rs371712630">rs371712630</a>
+                                    
+                                    
+                                    
+                                    
+                                
+                        </div>
+                        <div class="col-sm-12">
+                            <b>Exomiser ACMG: </b>
+                            
+                                    
+                                
+                                
+                                
+                                <span class="label label-default">UNCERTAIN_SIGNIFICANCE</span>
+                                
+                                <b>[]</b>
+                            
+                        </div>
+                        <div class="col-sm-12">
+                            <b>ClinVar: </b>
+                            
+                                    
+                                
+                                
+                                
+                                
+                                
+                                <span class="label label-default">CONFLICTING_PATHOGENICITY_INTERPRETATIONS</span>
+                                <a href="https://www.ncbi.nlm.nih.gov/clinvar/?term=192454%5Balleleid%5D">(criteria provided, conflicting interpretations)</a>
+                                
+                            </div>
+                            <div class="col-sm-6">
+                                <b>Variant score: 0.097</b>
+                                <span class="label label-info">CONTRIBUTING VARIANT</span>
+                                
+                                <dl class="list-unstyled">
+                                    <dt>Transcripts:</dt>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000354534.11">SCN8A:ENST00000354534.11:c.270G&gt;T:p.(=)</a>
+                                        
+                                    </dd>
+                                    <dd>
+                                        
+                                        <a href="https://grch37.ensembl.org/Homo_sapiens/Transcript/Summary?t=ENST00000627620.5">SCN8A:ENST00000627620.5:c.270G&gt;T:p.(=)</a>
+                                        
+                                    </dd>
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Pathogenicity Score: 1.00</b>-->
+                                <dl class="list-unstyled">
+                                    <dt>Pathogenicity Data:</dt>
+                                    
+                                    <dd>No
+                                        pathogenicity data
+                                    </dd>
+                                    
+                                </dl>
+                            </div>
+                            <div class="col-sm-3">
+                                <!--<b>Frequency Score: 0.95</b>-->
+                                <dl>
+                                    <dt>Frequency Data:</dt>
+                                    
+                                    <dd>1000Genomes: 0.0625%</dd>
+                                    <dd>TOPMed: 0.0625%</dd>
+                                    <dd>ExAC EAS: 0.1739%</dd>
+                                    <dd>ExAC SAS: 0.0062%</dd>
+                                    <dd>gnomAD_E_EAS: 0.1218%</dd>
+                                    <dd>gnomAD_E_OTH: 0.0549%</dd>
+                                    <dd>gnomAD_E_SAS: 0.0033%</dd>
+                                    <dd>gnomAD_G_EAS: 0.0617%</dd>
+                                    <dd>gnomAD_G_OTH: 0.1018%</dd>
+                                </dl>
+                            </div>
+                        </div> <!-- end variant row -->
+                    </div> <!-- end panel-body -->
+                <!--</div> &lt;!&ndash; end gene score section&ndash;&gt;-->
+            </div>
+
+            
+
+            
+
+             <!-- end gene scores -->
+            
+        </div>
+    </div>
+
+    
+
+    <div id="about">
+        <h3>About</h3>
+        <p>
+            The Exomizer is a Java program that functionally annotates variants from whole-exome
+            sequencing data starting from a VCF file (version 4). The functional annotation code is
+            based on <a href="https://github.com/charite/jannovar/">Jannovar</a> and uses
+            <a href="https://genome.ucsc.edu/">UCSC</a> KnownGene transcript definitions and
+            hg19 genomic coordinates
+        </p>
+        <p>
+            Variants are prioritized according to user-defined criteria on variant frequency, pathogenicity,
+            quality, inheritance pattern, and model organism phenotype data. Predicted pathogenicity data
+            was extracted from the <a href="https://www.ncbi.nlm.nih.gov/pubmed/21520341">dbNSFP</a> resource.
+        </p>
+        <p>
+            Developed by the Computational Biology and Bioinformatics group at the
+            <a href="https://genetik.charite.de/">Institute for Medical Genetics and Human Genetics</a> of the
+            <a href="https://www.charite.de">Charit&eacute; - Universit&auml;tsmedizin Berlin</a>, the Mouse
+            Informatics Group at the <a href="https://www.sanger.ac.uk/">Sanger Institute</a> and the Smedley group at
+            <a href="https://qmul.ac.uk/whri">Queen Mary University of London</a>.
+        </p>
+
+
+        <p>Problems, suggestions, or comments? Please <a href="mailto:peter.robinson@charite.de">let us know</a></p>
+    </div>
+</div>
+</body>
+</html>
diff --git a/example/iderare_example.yml b/example/iderare_example.yml
index 0bc790f..eb8263b 100644
--- a/example/iderare_example.yml
+++ b/example/iderare_example.yml
@@ -23,27 +23,29 @@ analysis:
 
   # HPO IDs of patient
   hpo_ids:
-    [
-      "HP:0002366",
-      "HP:0005561",
-      "HP:0001903",
-      "HP:0010972",
-      "HP:0001541",
-      "HP:0004333",
-      "HP:0001396",
-      "HP:0002910",
-      "HP:0001531",
-      "HP:0001399",
-      "HP:0001433",
-      "HP:0003073",
-      "HP:0003233",
-      "HP:0006568",
-      "HP:0002151",
-      "HP:0200114",
-      "HP:0001653",
-      "HP:0000938",
-      "HP:0001873",
-    ]
+  - HP:0000007
+  - HP:0001433
+  - HP:0001903
+  - HP:0001541
+  - HP:0010972
+  - HP:0005561
+  - HP:0001396
+  - HP:0001410
+  - HP:0002910
+  - HP:0001399
+  - HP:0000938
+  - HP:0001642
+  - HP:0200114
+  - HP:0003073
+  - HP:0003233
+  - HP:0001873
+  - HP:0002151
+  - HP:0031964
+  - HP:0031956
+  - HP:0002366
+  - HP:0006568
+  - HP:0004333
+  - HP:0001531
 
   # Library Name - Any kind of sequencing method (e.g. AgilentV6)
   library: AgilentV6