diff --git a/docs/dev-tools/backends/pipx.md b/docs/dev-tools/backends/pipx.md
index 7e3ecae49d..714e5b49cb 100644
--- a/docs/dev-tools/backends/pipx.md
+++ b/docs/dev-tools/backends/pipx.md
@@ -53,22 +53,23 @@ The version will be set in `~/.config/mise/config.toml` with the following forma
 
 Other syntax may work but is unsupported and untested.
 
-## Configuration
+## Settings
 
 Set these with `mise settings set [VARIABLE] [VALUE]` or by setting the environment variable listed.
 
-### `pipx_uvx`
+<script setup>
+import { data } from '/settings.data.ts';
+import Setting from '/components/setting.vue';
+const settings = data.find(s => s.key === 'node').settings;
+</script>
+<Setting v-for="setting in settings" :setting="setting" :key="setting.key" :level="3" />
 
-- Type: `bool`
-- Env: `MISE_PIPX_UVX`
-- Default: `false`
+## Tool Options
 
-If true, mise will use `uvx` instead of `pipx` if
-[`uv`](https://docs.astral.sh/uv/) is installed and on PATH.
-This makes installing CLIs _much_ faster by using `uv` as the package manager.
+The following [tool-options](/dev-tools/#tool-options) are available for the `pipx` backend:
 
-You can install it with mise:
-
-```sh
-mise use -g uv
-```
+| Option      | Description                                            | Example                                                                     |
+| ----------- | ------------------------------------------------------ | --------------------------------------------------------------------------- |
+| `extras`    | Install additional components                          | `"pipx:harlequin" = { version = "latest", extras = "postgres,s3" }          |
+| `pipx_args` | Additional arguments to pass to `pipx` when installing | `"pipx:black" = { version = "latest", pipx_args = "--preinstall" }`         |
+| `uvx_args`  | Additional arguments to pass to `uvx` when installing  | `"pipx:ansible-core" = { version = "latest", uvx_args = "--with ansible" }` |
diff --git a/docs/lang/node.md b/docs/lang/node.md
index 2e4fa455f1..b14a505de1 100644
--- a/docs/lang/node.md
+++ b/docs/lang/node.md
@@ -27,11 +27,8 @@ required system dependencies.
 <script setup>
 import { data } from '/settings.data.ts';
 import Setting from '/components/setting.vue';
-
 const settings = data.find(s => s.key === 'node').settings;
-
 </script>
-
 <Setting v-for="setting in settings" :setting="setting" :key="setting.key" :level="3" />
 
 ### Environment Variables
diff --git a/schema/mise.json b/schema/mise.json
index a8aaca3e0c..cc3fd9fb34 100644
--- a/schema/mise.json
+++ b/schema/mise.json
@@ -297,6 +297,15 @@
           "description": "Default to pinning versions when running `mise use` in mise.toml files.",
           "type": "boolean"
         },
+        "pipx": {
+          "additionalProperties": false,
+          "properties": {
+            "uvx": {
+              "description": "Use uvx instead of pipx if uv is installed and on PATH.",
+              "type": "boolean"
+            }
+          }
+        },
         "pipx_uvx": {
           "description": "Use uvx instead of pipx if uv is installed and on PATH.",
           "type": "boolean"
diff --git a/settings.toml b/settings.toml
index 1023e9d49a..898931515d 100644
--- a/settings.toml
+++ b/settings.toml
@@ -348,10 +348,25 @@ This sets `--pin` by default when running `mise use` in mise.toml files. This ca
 passing `--fuzzy` on the command line.
 """
 
+[pipx.uvx]
+type = "Bool"
+description = "Use uvx instead of pipx if uv is installed and on PATH."
+docs = """
+If true, mise will use `uvx` instead of `pipx` if
+[`uv`](https://docs.astral.sh/uv/) is installed and on PATH.
+This makes installing CLIs _much_ faster by using `uv` as the package manager.
+
+You can install it with mise:
+
+```sh
+mise use -g uv
+```
+"""
+
 [pipx_uvx]
-env = "MISE_PIPX_UVX"
 type = "Bool"
 description = "Use uvx instead of pipx if uv is installed and on PATH."
+hide = true
 
 [plugin_autoupdate_last_check_duration]
 env = "MISE_PLUGIN_AUTOUPDATE_LAST_CHECK_DURATION"
diff --git a/src/backend/pipx.rs b/src/backend/pipx.rs
index 7fe0537f02..64bd8335a3 100644
--- a/src/backend/pipx.rs
+++ b/src/backend/pipx.rs
@@ -85,7 +85,7 @@ impl Backend for PIPXBackend {
             .pipx_request(&ctx.tv.version, &ctx.tv.request.options());
 
         if settings.pipx_uvx {
-            CmdLineRunner::new("uv")
+            let mut cmd = CmdLineRunner::new("uv")
                 .arg("tool")
                 .arg("install")
                 .arg(pipx_request)
@@ -96,10 +96,13 @@ impl Backend for PIPXBackend {
                 .prepend_path(ctx.ts.list_paths())?
                 // Prepend install path so pipx doesn't issue a warning about missing path
                 .prepend_path(vec![ctx.tv.install_path().join("bin")])?
-                .prepend_path(self.dependency_toolset()?.list_paths())?
-                .execute()?;
+                .prepend_path(self.dependency_toolset()?.list_paths())?;
+            if let Some(args) = ctx.tv.request.options().get("uvx_args") {
+                cmd = cmd.args(shell_words::split(args)?);
+            }
+            cmd.execute()?;
         } else {
-            CmdLineRunner::new("pipx")
+            let mut cmd = CmdLineRunner::new("pipx")
                 .arg("install")
                 .arg(pipx_request)
                 .with_pr(ctx.pr.as_ref())
@@ -109,8 +112,11 @@ impl Backend for PIPXBackend {
                 .prepend_path(ctx.ts.list_paths())?
                 // Prepend install path so pipx doesn't issue a warning about missing path
                 .prepend_path(vec![ctx.tv.install_path().join("bin")])?
-                .prepend_path(self.dependency_toolset()?.list_paths())?
-                .execute()?;
+                .prepend_path(self.dependency_toolset()?.list_paths())?;
+            if let Some(args) = ctx.tv.request.options().get("pipx_args") {
+                cmd = cmd.args(shell_words::split(args)?);
+            }
+            cmd.execute()?;
         }
         Ok(())
     }