diff --git a/scripts/tests/run_python_test.py b/scripts/tests/run_python_test.py
index 267fb513952437..c67cbf7d75c93d 100755
--- a/scripts/tests/run_python_test.py
+++ b/scripts/tests/run_python_test.py
@@ -116,9 +116,10 @@ def forward_fifo(path: str, f_out: typing.BinaryIO, stop_event: threading.Event)
 @click.option("--quiet/--no-quiet", default=None,
               help="Do not print output from passing tests. Use this flag in CI to keep GitHub log size manageable.")
 @click.option("--load-from-env", default=None, help="YAML file that contains values for environment variables.")
+@click.option("--run", type=str, multiple=True, help="Run only the specified test run(s).")
 def main(app: str, factory_reset: bool, factory_reset_app_only: bool, app_args: str,
          app_ready_pattern: str, app_stdin_pipe: str, script: str, script_args: str,
-         script_gdb: bool, quiet: bool, load_from_env):
+         script_gdb: bool, quiet: bool, load_from_env, run):
     if load_from_env:
         reader = MetadataReader(load_from_env)
         runs = reader.parse_script(script)
@@ -141,7 +142,11 @@ def main(app: str, factory_reset: bool, factory_reset_app_only: bool, app_args:
             "No valid runs were found. Make sure you add runs to your file, see "
             "https://github.com/project-chip/connectedhomeip/blob/master/docs/testing/python.md document for reference/example.")
 
-    # Override runs Metadata with the command line arguments
+    if run:
+        # Filter runs based on the command line arguments
+        runs = [r for r in runs if r.run in run]
+
+    # Override runs Metadata with the command line options
     for run in runs:
         if factory_reset is not None:
             run.factory_reset = factory_reset