diff --git a/.github/workflows/nix.yml b/.github/workflows/nix.yml
new file mode 100644
index 00000000..322d1fb5
--- /dev/null
+++ b/.github/workflows/nix.yml
@@ -0,0 +1,40 @@
+name: Build and cache with Nix
+
+on:
+  workflow_dispatch:
+  push:
+    paths:
+    - '**'
+
+jobs:
+  build-and-cache:
+    runs-on: ${{ matrix.os }}
+    timeout-minutes: 740
+    strategy:
+      fail-fast: false
+      matrix:
+        os: [ubuntu-latest, macos-latest, macos-m1]
+    steps:
+    - name: Checkout repository
+      uses: actions/checkout@v3
+
+    - name: Set up Nix with caching
+      uses: kadena-io/setup-nix-with-cache/by-root@v3
+      with:
+        cache_url: s3://nixcache.chainweb.com?region=us-east-1
+        signing_private_key: ${{ secrets.NIX_CACHE_PRIVATE_KEY }}
+
+    - name: Set up AWS credentials
+      uses: aws-actions/configure-aws-credentials@v2
+      with:
+        aws-access-key-id: ${{ secrets.NIX_CACHE_AWS_ACCESS_KEY_ID }}
+        aws-secret-access-key: ${{ secrets.NIX_CACHE_AWS_SECRET_ACCESS_KEY }}
+        aws-region: us-east-1
+
+    - name: Give root user AWS credentials
+      uses: kadena-io/setup-nix-with-cache/copy-root-aws-credentials@v3
+
+    - name: Build and cache artifacts
+      run: |
+        echo Building the project and its devShell
+        nix build .#check --log-lines 500 --show-trace
diff --git a/flake.nix b/flake.nix
index 2652655f..af866caf 100644
--- a/flake.nix
+++ b/flake.nix
@@ -29,8 +29,22 @@
           defaultNix = import ./default.nix { inherit pkgs; };
           flake = defaultNix.flake;
           executable = defaultNix.default;
+          # This package depends on other packages at buildtime, but its output does not
+          # depend on them. This way, we don't have to download the entire closure to verify
+          # that those packages build.
+          mkCheck = name: package: pkgs.runCommand ("check-"+name) {} ''
+            echo ${name}: ${package}
+            echo works > $out
+          '';
         in  flake // {
           packages.default = executable;
           packages.chainweb-data-docker = defaultNix.dockerImage;
+
+          # Built by CI
+          packages.check = pkgs.runCommand "check" {} ''
+            echo ${self.packages.${system}.default}
+            echo ${mkCheck "devShell" flake.devShell}
+            echo works > $out
+          '';
         });
 }