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DavideTisi committed Aug 28, 2024
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# that are too infrequent to be observed over the time scale (ns-µs) accessible to
# molecular dynamics simulations. You can read one of the many excellent reviews
# on metadynamics (see e.g.
# `Bussi and Branduardi (2015) <https://doi.org/10.1002/9781118889886.ch1>`_)
# `Bussi and Branduardi (2015) <https://doi.org/10.1002/9781118889886.ch1>`_).
# In short, during a metadynamics simulation an adaptive biasing potential is
# built as a superimposition of Gaussians centered over configurations that have
# been previously visited by the trajectory. This discourages the system from remaining
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