diff --git a/vignettes/a_priori_dosing.Rmd b/vignettes/a_priori_dosing.Rmd
index 593262b..7311fd8 100644
--- a/vignettes/a_priori_dosing.Rmd
+++ b/vignettes/a_priori_dosing.Rmd
@@ -15,7 +15,6 @@ knitr::opts_chunk$set(
 set.seed(1)
 library(rxode2)
 setRxThreads(2L)  # limit the number of threads
-knitr::opts_chunk$set(warning = FALSE, message = FALSE) 
 ```
 
 ```{r setup}