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CRAM compatibility #244

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Jwong684 opened this issue Jun 27, 2022 · 1 comment

Jwong684 commented Jun 27, 2022

Hi Markus,

More of a general question - I was wondering if purecn would eventually be CRAM compatible?

Thank you!

Owner

lima1 commented Jun 27, 2022

I'm using Rsamtools. There is a developer version with CRAM support it seems. Bioconductor/Rsamtools#21

It probably won't work out-of-the-box, but I'm happy to accept a pull request.

You can always use GATK4 to calculate coverages, I would assume they support CRAM?

lbeltrame mentioned this issue

Support creating a PoN with PureCN nf-core/createpanelrefs#36

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