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Clinical-Lab-Data-Analysis

Demographics

Table 1: Age

Category Drug Group Mean Drug Group Std Dev Control Group Mean Control Group Std Dev
Recipient 41.94 10.62 36.70 11.42
Donor 49.02 11.41 47.67 11.43

Table 2: Relationship of Recipient with Donor

Category Drug Group Records Control Group Records
Related 3 6
Spousal 5 -
Unrelated 2 4
Total 10 10

Table 3: Gender Analysis

Category Drug Group N Control Group N
Recipient 10 1 (female), 8 (male)
Donor 10 (female) 6 (female), 3 (male)

Insights:

A. Age:

  1. Drug Group: Recipients have an average age of 41.94 years (Std Dev: 10.62), while donors average 49.02 years (Std Dev: 11.41).
  2. Control Group: Recipients are younger, averaging 36.70 years (Std Dev: 11.42), with donors at 47.67 years (Std Dev: 11.43).

B. Relationship with Donor:

  1. Drug Group: Most donors are spousal (5), followed by related (3), and unrelated (2).
  2. Control Group: More recipients are related to donors (6) compared to unrelated (4).

C. Gender Analysis:

  1. Drug Group: All recipients are male (10) and all donors are female (10).
  2. Control Group: Recipients are mostly male (8), with one female, while donors are predominantly female (6), with three males.

Lab Data

Table 1: Analysis of Serum Creatinine on Different Days

Day Drug Group N Drug Group Mean Drug Group Std Drug Group Range Control Group N Control Group Mean Control Group Std Control Group Range
day3 10 1.87 1.54 5.30 9 1.83 0.59 1.90
day7 10 1.53 0.73 2.60 9 1.64 0.41 1.30
day15 8 1.58 0.52 1.80 9 1.68 0.62 2.00
day30 7 1.62 0.18 0.50 8 1.46 0.39 1.10
day90 3 1.60 0.10 0.20 4 1.43 0.15 0.30
day180 2 1.55 0.35 0.50 2 1.50 0.14 0.20
day360 2 1.50 0.14 0.20 0 . . .
day720 1 1.50 . 0.00 0 . . .

Table 2: Analysis of HB on Different Days

Day Drug Group N Drug Group Mean Drug Group Std Drug Group Range Control Group N Control Group Mean Control Group Std Control Group Range
day0 8 9.03 1.68 5.70 9 8.39 1.80 5.40
day3 8 8.76 3.41 10.50 9 8.68 2.17 5.80
day7 8 9.23 2.24 7.50 9 8.83 2.60 8.20
day14 8 10.14 1.63 5.80 8 10.33 1.66 4.50
day30 7 10.19 1.45 4.10 8 12.23 1.29 3.40
day90 3 12.57 0.29 0.50 4 11.85 1.42 3.40
day180 2 12.55 1.34 1.90 2 14.10 0.28 0.40
day360 2 13.10 0.99 1.40 0 . . .
day720 0 . . . 0 . . .

Table 3: Analysis of Platelets on Different Days

Day Drug Group N Drug Group Mean Drug Group Std Drug Group Range Control Group N Control Group Mean Control Group Std Control Group Range
day0 4 221.50 62.96 132.00 9 225.7 54.04 166.8
day3 4 166.75 36.37 84.00 9 197.9 34.58 157.7
day7 6 227.67 134.36 397.00 9 9.23 2.24 7.50
day14 3 318.33 112.45 204.00 8 10.14 1.63 5.80
day30 2 168.00 32.53 46.00 7 10.19 1.45 4.10
day90 1 190.00 . 0.00 3 12.57 0.29 0.50
day180 0 . . . 2 12.55 1.34 1.90
day360 2 226.00 155.56 220.00 2 13.10 0.99 1.40
day720 1 287.00 . 0.00 0 . . .

Table 4: Analysis of Urine Test

Day Drug Group Records Observed Control Group Records Observed
day0 0 0
day3 0 1
day7 0 1
day14 4 4
day30 7 5
day90 4 2
day180 2 2
day360 2 0
day720 0 0

Table 5: Analysis of CD3 on Different Days

Day Drug Group N Drug Group Mean Drug Group Std Drug Group Range Control Group N Control Group Mean Control Group Std Control Group Range
day0 5 837.00 509.54 1137.00 2 198.50 72.83 103.00
day3 7 42.29 55.94 122.00 1 298.00 . 0.00
day7 2 543.50 218.50 309.00 0 . . .
day14 0 . . . 1 570.00 . 0.00
day30 4 318.25 246.33 548.00 4 648.75 300.27 663.00
day90 1 236.00 . 0.00 5 943.80 644.86 1287.00
day180 1 523.00 . 0.00 1 780.00 . 0.00
day360 0 . . . 0 . . .
day720 1 1042.00 . 0.00 0 . . .

Table 6: Analysis of CD4 on Different Days

Day Drug Group N Drug Group Mean Drug Group Std Drug Group Range Control Group N Control Group Mean Control Group Std Control Group Range
day0 6 401.83 342.32 859.00 2 98.00 45.25 64.00
day3 7 11.14 23.03 63.00 1 124.00 . 0.00
day7 2 295.00 213.55 302.00 0 . . .
day14 0 . . . 1 157.00 . 0.00
day30 4 107.25 109.54 257.00 4 246.50 140.71 330.00
day90 1 176.00 . 0.00 5 463.40 437.96 890.00
day180 1 306.00 . 0.00 1 306.00 . 0.00
day360 0 . .

Summary of lab data

  1. Serum Creatinine Analysis Day 3: Drug group had a higher mean serum creatinine (1.87) than the control group (1.83). Day 7: Both groups show a reduction in mean serum creatinine, but the control group shows a more significant reduction.
  2. Hemoglobin (HB) Analysis Day 14: Drug group's HB levels increased significantly from 9.23 to 10.14, while the control group's HB rose from 8.83 to 10.33. Day 180: Control group showed a greater increase (14.10) compared to the drug group (12.55).
  3. Platelet Count Analysis Day 14: Drug group had a significantly higher mean platelet count (318.33) compared to the control group. Day 360: The drug group maintained higher platelet counts (226.00) than the control group.
  4. CD3 and CD4 Counts CD3 Day 30: Control group showed higher mean CD3 levels (648.75) compared to the drug group (318.25). CD4 Day 30: Control group also showed higher CD4 levels (246.50) compared to the drug group (107.25).
  5. Viral Infections Both groups reported two cases of viral infection.

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