diff --git a/src/sssom/obo.epm.json b/src/sssom/obo.epm.json
index c6a41bc2..ea70fdf1 100644
--- a/src/sssom/obo.epm.json
+++ b/src/sssom/obo.epm.json
@@ -262,6 +262,20 @@
             "https://purl.obolibrary.org/obo/ATO_"
         ]
     },
+    {
+        "prefix": "AfPO",
+        "prefix_synonyms": [
+            "afpo"
+        ],
+        "uri_prefix": "http://purl.obolibrary.org/obo/AfPO_",
+        "uri_prefix_synonyms": [
+            "http://bioregistry.io/AfPO:",
+            "http://bioregistry.io/afpo:",
+            "https://bioregistry.io/AfPO:",
+            "https://bioregistry.io/afpo:",
+            "https://purl.obolibrary.org/obo/AfPO_"
+        ]
+    },
     {
         "pattern": "^\\d{7}$",
         "prefix": "BCGO",
@@ -9957,10 +9971,10 @@
     },
     {
         "prefix": "cls",
-        "uri_prefix": "https://cls.shop/",
+        "uri_prefix": "https://www.cytion.com/",
         "uri_prefix_synonyms": [
             "http://bioregistry.io/cls:",
-            "http://cls.shop/",
+            "http://www.cytion.com/",
             "https://bioregistry.io/cls:"
         ]
     },
@@ -11732,11 +11746,11 @@
         "uri_prefix_synonyms": [
             "http://bioregistry.io/DSMZCellDive:",
             "http://bioregistry.io/dsmz:",
-            "http://celldive.dsmz.de/cellline/",
+            "http://celldive.dsmz.de/celllines/",
             "http://www.dsmz.de/collection/catalogue/details/culture/",
             "https://bioregistry.io/DSMZCellDive:",
             "https://bioregistry.io/dsmz:",
-            "https://celldive.dsmz.de/cellline/"
+            "https://celldive.dsmz.de/celllines/"
         ]
     },
     {
@@ -11802,8 +11816,10 @@
         "uri_prefix": "https://www.phe-culturecollections.org.uk/products/celllines/generalcell/detail.jsp?collection=ecacc_gc&refId=",
         "uri_prefix_synonyms": [
             "http://bioregistry.io/ecacc:",
+            "http://www.culturecollections.org.uk/products/celllines/detail.jsp?refId=",
             "http://www.phe-culturecollections.org.uk/products/celllines/generalcell/detail.jsp?collection=ecacc_gc&refId=",
-            "https://bioregistry.io/ecacc:"
+            "https://bioregistry.io/ecacc:",
+            "https://www.culturecollections.org.uk/products/celllines/detail.jsp?refId="
         ]
     },
     {
@@ -12524,10 +12540,8 @@
         "uri_prefix": "https://www.ebi.ac.uk/cgi-bin/ipd/estdab/print_cell.cgi?ESTDAB-",
         "uri_prefix_synonyms": [
             "http://bioregistry.io/estdab:",
-            "http://www.ebi.ac.uk/cgi-bin/ipd/estdab/print_cell.cgi?",
             "http://www.ebi.ac.uk/cgi-bin/ipd/estdab/print_cell.cgi?ESTDAB-",
-            "https://bioregistry.io/estdab:",
-            "https://www.ebi.ac.uk/cgi-bin/ipd/estdab/print_cell.cgi?"
+            "https://bioregistry.io/estdab:"
         ]
     },
     {
@@ -19792,12 +19806,14 @@
             "http://n2t.net/omia:",
             "http://omia.angis.org.au/retrieve.shtml?pid=",
             "http://omia.org/OMIA",
+            "http://www.omia.org/OMIA",
             "https://bio2rdf.org/omia:",
             "https://bioregistry.io/omia:",
             "https://identifiers.org/omia/",
             "https://identifiers.org/omia:",
             "https://n2t.net/omia:",
-            "https://omia.angis.org.au/retrieve.shtml?pid="
+            "https://omia.angis.org.au/retrieve.shtml?pid=",
+            "https://www.omia.org/OMIA"
         ]
     },
     {
@@ -20079,9 +20095,9 @@
             "http://identifiers.org/orphanet:",
             "http://n2t.net/orphanet:",
             "http://orphanet.bio2rdf.org/describe/?url=http://bio2rdf.org/orphanet:",
-            "http://www.orpha.net/consor/cgi-bin//OC_Exp.php?lng=EN&Expert=",
             "http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=",
             "http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=",
+            "http://www.orpha.net/en/disease/detail/",
             "https://bio2rdf.org/orphanet:",
             "https://bioregistry.io/ORPHA:",
             "https://bioregistry.io/orphanet:",
@@ -20089,10 +20105,10 @@
             "https://identifiers.org/orphanet:",
             "https://n2t.net/orphanet:",
             "https://orphanet.bio2rdf.org/describe/?url=http://bio2rdf.org/orphanet:",
-            "https://www.orpha.net/consor/cgi-bin//OC_Exp.php?lng=EN&Expert=",
             "https://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=EN&Expert=",
             "https://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=",
-            "https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert="
+            "https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=",
+            "https://www.orpha.net/en/disease/detail/"
         ]
     },
     {