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mutation_search.html
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<!DOCTYPE html>
<html lang="en">
<head>
<meta charset="utf-8">
<title>Mutation Search - GExplore</title>
<link rel="stylesheet" href="style.css" type="text/css">
<link rel="icon" href="assets/favicon.png" type="image/png">
</head>
<body>
<div class="search-wrapper">
<div id="header">
<a href="home.html">
<img src="assets/GExplore_logo.png" alt="GExplore Logo" class="logo">
</a>
<div id="topnav">
<ul>
<li class="active"><a href="home.html"><span class="text">Home</span></a></li>
<li><a><span class="text">Search</span> <span class="angle"></span></a>
<ul class="dropdown">
<li><a href="gene_search.html">Genes</a></li>
<li><a href="mutation_search.html">Mutations</a></li>
<li><a href="protein_search.html">Proteins</a></li>
<li><a href="expression_stage_search.html">Stage Expressions</a></li>
<li><a href="expression_tissue_search.html">Tissue Expressions</a></li>
<li><a href="expression_embryo_search.html">Embryo Expressions</a></li>
</ul>
</li>
<li><a><span class="text">Tools</span> <span class="angle"></span></a>
<ul class="dropdown">
<li><a href="compare.html">Compare</a></li>
<li><a href="convert.html">Convert</a></li>
</ul>
</li>
<li><a href="help.html"><span class="text">Help</span></a></li>
<li><a href="about.html"><span class="text">About</span></a></li>
</ul>
</div>
</div>
<div id="search-vertical-content">
<!-- Hero Section -->
<div id="search-intro">
<div class="search-hero-section">
<h2>Search for Mutations in <i>C. elegans</i> Genes</h2>
<p>The database includes alleles affecting exons, splice junctions, and those without positional information from Wormbase release 292 (April 2024).</p>
<p>The Million Mutation Project offers over 2,000 heavily mutagenized strains, while the KO consortium is generating null mutations using CRISPR/Cas9.</p>
<a href="help.html#mutation-database" target="_blank">Learn More</a>
</div>
</div>
<!-- Wrapper for padding -->
<div class="search-param-wrapper">
<div id="search-param">
<div class="search-param-column-1">
<!-- Gene Name Group -->
<div class="form-group">
<h4>
Gene Name
<img src="assets/help-icon.png" alt="Help" class="search-page-help-icon">
</h4>
<div class="search-page-help-content">
<p>Enter gene identifiers like WormBase gene IDs, locus names, or gene/protein sequence names. You can use commas, spaces, or wildcards to search multiple genes at once. <a href="help.html#gene-search-field" target="_blank">Learn more</a></p>
</div>
<textarea id="gene-names" name="gene-names" placeholder="Enter a gene name. Separate each additional name with a comma."></textarea>
<div class="splice-variant-row">
<label for="longest-splice-variant">
<input type="checkbox" id="longest-splice-variant" name="longest-splice-variant" checked>
<h5>Only longest splice variant</h5>
</label>
</div>
<div class="more-than-one-gene-deletion">
<label>
<input type="checkbox" id="multiple-affecting-deletion" name="multiple-affecting-deletion" checked>
<h5>Do not show deletions affecting more than one gene</h5>
</label>
</div>
</div>
<!-- Protein Domain group -->
<div class="form-group">
<h4>
Protein Domain
<img src="assets/help-icon.png" alt="Help" class="search-page-help-icon">
</h4>
<div class="search-page-help-content">
<p>Enter domain abbreviations or SMART/Pfam IDs to search for specific protein domains. <a href="help.html#protein-domain-search-fields" target="_blank">Learn more</a></p>
</div>
<h5>Domain</h5>
<textarea id="protein-domain" name="protein-domain" placeholder="Enter a protein domain. Separate each additional domain with a comma."></textarea>
</div>
<!-- Allele Name Group -->
<div class="form-group">
<h4>
Allele Name
<img src="assets/help-icon.png" alt="Help" class="search-page-help-icon">
</h4>
<div class="search-page-help-content">
<p>??? (e.g. gk123, hd126)</p>
</div>
<textarea id="allele" name="allele" placeholder="Enter an allele name. Separate each additional name with a comma."></textarea>
</div>
</div>
<div class="search-param-column-2">
<!-- Mutation Type group -->
<div class="form-group">
<h4>
Select Mutation Type
<img src="assets/help-icon.png" alt="Help" class="search-page-help-icon">
</h4>
<div class="search-page-help-content">
<p>Limit your search results to mutation types like nonsense and deletions that remove a specific percentage of protein. These filters help find mutations with major effects on protein function. <a href="help.html#mutation-search-page" target="_blank">Learn more</a></p>
</div>
<!-- Checkboxes and Inputs -->
<div class="mutation-type-container">
<label>
<input type="checkbox" name="mutation-type" value="missense" checked>
Missense
</label>
<label>
<input type="checkbox" name="mutation-type" value="nonsense-removing" checked>
Nonsense removing greater than
<input type="text" name="nonsense-removing-percentage" style="width: 50px;"> <span style="font-family: 'Consolas', 'Courier New', Courier, monospace;">%</span>
</label>
<label>
<input type="checkbox" name="mutation-type" value="splice-donor-acceptor" checked>
Splice donor / acceptor
</label>
<label>
<input type="checkbox" name="mutation-type" value="deletions-removing" checked>
Deletions removing greater than
<input type="text" name="deletions-removing-percentage" style="width: 50px;"> <span style="font-family: 'Consolas', 'Courier New', Courier, monospace;">%</span>
</label>
<label>
<input type="checkbox" name="mutation-type" value="indels" checked>
Indels
</label>
<label>
<input type="checkbox" name="mutation-type" value="readthroughs" checked>
Readthroughs
</label>
<label>
<input type="checkbox" name="mutation-type" value="unknown" checked>
Unknown
</label>
</div>
</div>
<!-- Mutation Source group -->
<div class="form-group">
<h4>
Select Mutation Source
<img src="assets/help-icon.png" alt="Help" class="search-page-help-icon">
</h4>
<div class="search-page-help-content">
<p>Filter mutations based on their origin, such as the Million Mutation Project or KO Consortium, to focus on mutations with varying impacts. <a href="help.html#mutation-search-page" target="_blank">Learn more</a></p>
</div>
<!-- Checkboxes -->
<div class="mutation-source-container">
<label>
<input type="checkbox" name="mutation-source" value="million-mutation-project" checked>
Million Mutation Project
</label>
<label>
<input type="checkbox" name="mutation-source" value="ko-consortium" checked>
KO consortium
</label>
<label>
<input type="checkbox" name="mutation-source" value="other" checked>
Other
</label>
</div>
</div>
</div>
</div>
</div>
<div class="form-actions">
<button type="reset">Clear</button>
<button type="submit" id="search-button" disabled>Search</button>
</div>
</div>
</div>
<!-- Main JavaScript file -->
<script src="script.js"></script>
<!-- Autosuggest JavaScript files -->
<script src="javascript/autosuggest_list_domains.js"></script>
</body>
</html>