Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Further refine dealing with dead cells #648

Open
aarmey opened this issue Oct 5, 2020 · 3 comments
Open

Further refine dealing with dead cells #648

aarmey opened this issue Oct 5, 2020 · 3 comments
Assignees
Labels
wontfix This will not be worked on

Comments

@aarmey
Copy link
Member

aarmey commented Oct 5, 2020

We have more death observations now that we're not throwing out cells. We should evaluate how they're distributed. It looks like the times are potentially exponentially distributed, which would make fitting them much easier.

I'm not sure we need to include this in the current paper, but the death times could be interesting as follow-up on their own.

@Farnazmdi
Copy link
Contributor

Farnazmdi commented Oct 23, 2020

Forgot to mention it here, I fitted an exponential to each concentration in #676 in the figure13. I can try and write a distribution function for them and add them to the likelihood. I remember you said it is not urgent for now, please let me know if it is a reasonable time to start working on it, or there are other priorities.

@aarmey
Copy link
Member Author

aarmey commented Oct 23, 2020

I think it's reasonable to try. It could be good to get Readthedocs working... I don't think there's one urgent thing.

@Farnazmdi Farnazmdi self-assigned this Oct 23, 2020
@Farnazmdi
Copy link
Contributor

note for me to remember: the last time we visited this, we figured that since the distribution of death times is not independent of the phase duration times, due to censoring, it is not very straight forward to pursue this.

@aarmey aarmey added the wontfix This will not be worked on label Dec 31, 2020
Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
wontfix This will not be worked on
Projects
None yet
Development

No branches or pull requests

2 participants